Epidemiology Commons^™

Analysis Of Strategies For Successful Identification, Reporting, And Prevention Of Carbapenem-Resistant Enterobacteriaceae (Cre) In Acute Health Care Facilities In New York State, Christen Leigh Mayer

Legacy Theses & Dissertations (2009 - 2024)

Background

Health Promoting Lifestyle Profile Of Asian Indians In The U.S. : Analysis Of Data From The Diabetes Among Indian Americans Study, Sanghamitra Siddharam Savadatti

Legacy Theses & Dissertations (2009 - 2024)

This dissertation sought to investigate the associations between health promoting lifestyle behaviors and chronic cardiometabolic conditions among Asian Indians residing in the U.S.

Correlates Of Life-Time History Of Purchasing Sex Services By Men In Saint Petersburg And Leningrad Oblast, Russian Federation, Polina Girchenko

Legacy Theses & Dissertations (2009 - 2024)

Background. Commercial sex workers (CSW) in Russian Federation are at high risk of HIV infection and transmission as a result of unsafe sexual and injecting behaviors. Their clients might be at increased risk of acquiring HIV; however, little is known about the population of men purchasing sex services. This study’s goal is to investigate factors associated with a history of purchasing sex services by men in Saint Petersburg and Leningrad Oblast, Russian Federation.

Study Of Human Ovarian Follicular Fluid High Density Lipoprotein (Hdl) And Embryo Quality During In Vitro Fertilization (Ivf), Keewan Kim

Legacy Theses & Dissertations (2009 - 2024)

Follicular fluid (FF) is in direct contact with granulosa cells that surround a developing oocyte, and high density lipoprotein (HDL) is the sole lipoprotein found in FF. Therefore, we investigated 41 FF HDL particle components, including 26 HDL-cholesterol (HDL-C) subfractions measured for particle size, apolipoproteins, enzymes, and lipophilic micronutrients, in association with embryo quality on 180 women undergoing in vitro fertilization (IVF).

The Relationship Between Area Poverty Rate And Site-Specific Cancer Incidence In The United States, Francis P. Boscoe, Christopher J. Johnson, Recinda L. Sherman, David G. Stinchcomb, Ge Lin, Kevin A. Henry

Epidemiology & Biostatistics Faculty Scholarship

BACKGROUND

The relationship between socioeconomic status and cancer incidence in the United States has not traditionally been a focus of population-based cancer surveillance systems.

METHODS

Nearly 3 million tumors diagnosed between 2005 and 2009 from 16 states plus Los Angeles were assigned into 1 of 4 groupings based on the poverty rate of the residential census tract at time of diagnosis. The sex-specific risk ratio of the highest-to-lowest poverty category was measured using Poisson regression, adjusting for age and race, for 39 cancer sites.

RESULTS

For all sites combined, there was a negligible association between cancer incidence and poverty; however, …

Breast Cancer Susceptibility : An Education Intervention And Genetic Epidemiology Study, Nur Zeinomar

Legacy Theses & Dissertations (2009 - 2024)

Background: Breast cancer is the most frequently diagnosed cancer (aside from non-melanoma skin cancers) and the second leading cause of cancer deaths among women in the United States. Our studies aimed to assess the effectiveness of a breast cancer educational intervention and to investigate genetic influences on the risk of post-menopausal breast cancer. The overarching theme and public health relevance of this dissertation was that our findings provided leads for breast cancer prevention.

Predictors Of Attrition Among Participants In A Worksite Wellness Program, Yvonne A. Johnston

Legacy Theses & Dissertations (2009 - 2024)

Objectives: The purpose of this secondary data analysis was to examine "stage of change" as a predictor of attrition among participants in a worksite wellness program. A Conceptual Model of Attrition was developed to examine health screening, health risk appraisal (HRA), and demographic predictors of attrition as well.

Influenza Hospitalizations In New York State 2007-2013 : Impact Of Vaccine And Antiviral Treatment Effectiveness In Reducing Severity Of Illness, Mary Dundas

Legacy Theses & Dissertations (2009 - 2024)

Background: Underlying medical conditions are known risk factors for increased severity of infectious diseases, including influenza. Although most studies on disease severity, underlying medical conditions, and prevention/treatment effectiveness occurred during the pandemic 2009-2010 season, data is also available for seasons when influenza virus B and influenza virus A subtypes pH1N1, seasonal H1N1, and H3N2 were circulating.

Disparities Among Hispanic Ethnicity And Stage At Diagnosis For Invasive Breast And Colorectal Cancer, Raquel Velazquez

Legacy Theses & Dissertations (2009 - 2024)

Objective: To assess the relationship between ethnicity and stage at diagnosis among invasive cases of breast and colorectal cancer.

An Evaluation Of Factors Leading To The Risk And Detection Of Thyroid Cancer, Thomas James O'Grady

Legacy Theses & Dissertations (2009 - 2024)

Abstract:

Paternal Occupational Pesticide Exposure And Neural Tube Defects In The National Birth Defects Prevention Study, Stacy Marie Pettigrew

Legacy Theses & Dissertations (2009 - 2024)

ABSTRACT

Sex Work And Daily Alcohol Use May Increase Hiv Risks Of Women Who Inject Drugs In Ukraine, Tetyana Vasylyeva

Legacy Theses & Dissertations (2009 - 2024)

Background: Between 10 - 50% of female PWID in former USSR countries, where HIV epidemics are driven by injecting drug use, are reported to exchange sex for money, drugs or goods. Research in the region shows contradictory data on the association between exchange sex and HIV for PWID, and suggests that this association might be influenced by other factors. Since female PWID who exchange sex might be a bridge population between PWID and other people, it is important to monitor their risks and suggest timely interventions.

Sleep Duration And Diabetes In An Adult Population Of Rural Upstate New York, Tarak Shrestha

Legacy Theses & Dissertations (2009 - 2024)

Introduction: Within the past five decades, there has been a rapid increase in the number of diabetic cases in the US. The number of diabetic cases increased from 1.5 million in 1959 to 25.8 million in 2011. Around the same time period, the average sleep duration per night decreased from 8 hours to 6.9 hours.

Psychological Features Of Abstinent Heroin Users And Predictors Of Their Improvement During Rehabilitation In Saint-Petersburg, Russia, Timofey Galankin

Legacy Theses & Dissertations (2009 - 2024)

Objective: Find predictors of adherence to post-detoxification rehabilitation programs in opiate intravenous drug users (IDUs) in Russia. Assess whether longer-term rehabilitation programs improve participants' psychological profiles more than shorter-term ones.

Medication Use And Patients Co-Infected With Human Immunodeficiency Virus And Hepatitis C Virus : Quantifying The Prevalence And Identifying The Predictors Of Clinically Significant Drug-Drug Interactions Associated With Therapy Containing First Generation Non-Structural 3a Serine Protease Inhibitors, Nimish Patel

Legacy Theses & Dissertations (2009 - 2024)

This dissertation enhances our understanding of clinically significant drug-drug interactions (CSDDIs) and contraindicated drug interactions among patients with human immunodeficiency virus (HIV) and hepatitis C virus (HCV) coinfection before and after the addition of HCV therapy including first generation non-structural (NS) 3A serine protease inhibitors. This is important to understand because the clinical sequelae of untreated chronic HCV infection are devastating yet drug-drug interactions greatly complicate treatment for these patients. The HIV/HCV coinfected population is a population that is particularly vulnerable because they are using a high volume of medications. Specifically, the standard of care for patients with HIV infection …

Atrazine In Maternal Drinking Water Supply Below The Federal Maximum Contaminant Level And Risk Of Preterm Birth, Small For Gestational Age, Cryptorchidism And Hypospadias, Daniel Rice

Legacy Theses & Dissertations (2009 - 2024)

The prevalence of preterm birth, small for gestational age (SGA), and hypospadias has been increasing for several decades in the U.S resulting in significant morbidity and mortality and direct costs to society. Drinking water provides a mechanism for prolonged chronic exposure to environmental contaminants but is one of the least assessed environmental exposures in pregnancy and birth outcomes. To test the hypothesis that maternal exposure to atrazine through drinking water during pregnancy, or one or more trimesters of gestation, is associated with an increased risk of preterm birth, small for gestational age, cryptorchidism and hypospadias a retrospective cohort study was …

Novel Partner Notification Approaches In New York State, And Antibiotic Resistance In The Management Of Chlamydia Trachomatis Infections, Christopher Frank Davis

Legacy Theses & Dissertations (2009 - 2024)

Chlamydia trachomatis (chlamydia) is the most frequently reported notifiable disease in the United States. This dissertation provides an evaluation of chlamydia treatment and control through three different lenses: 1) patient views on a novel strategy to facilitate treatment, 2) student perceptions about materials to promote treatment of sexual partners, and 3) evidence regarding recurrent infection etiology.

Maternal Characteristics And Factors Associated With Hepatitis C (Hcv) Infection Among Hiv-Positive Pregnant Women In Ukraine, 2010-2011, Liudmyla Slobodianyk

Legacy Theses & Dissertations (2009 - 2024)

Objective: Determine the association between risk factors for Hepatitis C and hepatitis C (HCV) infection among HIV-positive pregnant women in Ukraine.

Social Support And Risky Sexual Behavior Among Male Migrant Market Workers From Central Asia In Almaty, Kazakhstan, Gaukhar Mergenova

Legacy Theses & Dissertations (2009 - 2024)

Background: Many studies have shown that risky sexual behavior leads to increased rates of HIV infection among labor migrants. However, little is known about the role of social support in risky sexual behavior among labor migrants in Kazakhstan. This study explores the potential association between social support and risky sexual behaviors among male migrant market vendors in Almaty, Kazakhstan.

Perfluorinated Compounds, Thyroid Function, And Neuropsychological Status In Older Residents Of Upper Hudson River Communities, Srishti Shrestha

Legacy Theses & Dissertations (2009 - 2024)

Perfluorinated compounds (PFCs) are widespread in the environment. Minimal data exist regarding the neurotoxicity and thyroid disruptive property of PFCs in aging populations and the possible mediating effects of thyroid hormones (THs). In this study, we assessed associations among PFCs, thyroid function, and neuropsychological status, and determined if the neurotoxic effects of PFCs are mediated by changes in THs in an aging population. We measured perfluorooctanoic acid (PFOA), perfluorooctane sulfonate (PFOS), thyroid stimulating hormone (TSH), total thyroxine (T4), free T4 (fT4), and total triiodothyronine (T3) in serum and performed neuropsychological tests in men and women aged 55-74 years and living …

A Population-Based Case-Control Study Of The Association Between Extreme Heat Events And Neural Tube Defects And Oral Clefts, Aida Soim

Legacy Theses & Dissertations (2009 - 2024)

With climate change it is expected that extreme weather events will become more frequent and longer in duration. The health consequences of maternal exposure during pregnancy to extreme heat events are not well understood in spite of biological plausibility for adverse effects suggested by prior findings. There is very limited research that explores the relationship between extreme heat events and birth defects. The overall goal of this line of research was to determine whether heatwaves (HW) are associated with two major classes of birth defects: neural tube defects (NTDs) and oral clefts. One component of this project aimed to describe …

Initiation And Completion Of Adjuvant Chemotherapy Among Colorectal Cancer Patients, Ashar Ata

Legacy Theses & Dissertations (2009 - 2024)

Introduction: For regionally advanced colorectal cancers resection followed by adjuvant chemotherapy (ACT) is the recommended treatment. Despite consensus on benefits, studies have shown that a significant proportion of patients do not initiate it. Among those who initiate the survival benefits of chemotherapy cannot be fully realized without completed treatment. Without supplementing treatment information from insurance claims cancer registries are inadequate for assessment of ACT utilization. This study was aimed at measuring the initiation and completion of ACT among colorectal cancer patients and identifying the associated factors.

Occupational Exposure To Ultraviolet Radiation And Risk Of Non-Melanoma Skin Cancer In A Multinational European Study, Simona Surdu, Edward F. Fitzgerald, Michael S. Bloom, Francis P. Boscoe, David Orlo Carpenter, Richard F. Haase, Eugen S. Gurzau, Peter Rudnai, Kvetoslava Koppova, Joelle Fevotte, Giovanni Leonardi, Marie Vahter, Walter Goessler, Rajiv Kumar, Tony Fletcher

Epidemiology & Biostatistics Faculty Scholarship

Background: Studies suggest that ambient sunlight plays an important role in the pathogenesis of non-melanoma skin cancers (NMSC). However, there is ongoing controversy regarding the relevance of occupational exposure to natural and artificial ultraviolet radiation (UV) radiation.

Objectives: We investigated potential associations between natural and artificial UV radiation exposure at work with NMSC in a case-control study conducted in Hungary, Romania, and Slovakia. Methods: Occupational exposures were classified by expert assessment for 527 controls and 618 NMSC cases (515 basal cell carcinoma, BCC). Covariate information was collected via interview and multiple logistic regression models were used to assess associations between …

In Utero Exposure To Antiretroviral Medication And Congenital Malformation Outcomes In New York State 1998-2010, Stephen Goins

Legacy Theses & Dissertations (2009 - 2024)

Objective: To examine the relationships between HIV ARV use during pregnancy and congenital malformations outcomes in New York State.

Hypertension Prevalence Among Adults In The United States (Nhanes 2007-2010) : Are There Race And Hispanic Origin Differences?, Philip M. Dimura

Legacy Theses & Dissertations (2009 - 2024)

Purpose: To investigate the prevalence of hypertension across race and ethnic categories in the National Health and Nutrition Examination Survey for years 2007 to 2010.

Alternative Vaccination Schedules (Avs) : Detection Of Avs In New York State Using Immunization Registry Data, Jessica A. Nadeau

Legacy Theses & Dissertations (2009 - 2024)

Intentional deviation from the recommended childhood vaccine schedule (RVS), referred to as an alternative vaccination schedule (AVS) is becoming increasingly prevalent in the United States. Physicians may accommodate vaccine-hesitant parents with an AVS as a compromise position to allow some vaccinations to be given, but in doing so children remain vulnerable to vaccine-preventable disease for a longer period of time. This research expands upon the nascent literature by proposing a unified definition of AVS, quantifying the prevalence of infants following an AVS in New York State (NYS) (exclusive of New York City) by geographic area and community and medical practice …

Exposure To Persistent Organic Pollutants And Metabolic Diseases, Zafar Zayirovich Aminov

Legacy Theses & Dissertations (2009 - 2024)

Background: The metabolic syndrome (MetS) is a group of diseases that tend to occur together, including diabetes, hypertension, central obesity, cardiovascular disease and hyperlipidemia. Exposure to persistent organic pollutants (POPs) such as polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs) have been associated with increased risk of development of several of the components of the MetS.

Quantitative Evaluation Of Antibiotic Exposure-Response Relationships Among Patients With Serious Staphylococcal Infections, Thomas Patrick Lodise

Legacy Theses & Dissertations (2009 - 2024)

This dissertation advances our understanding of antimicrobial exposure-response relationships among patients with serious infections due to Staphylococcus aureus. The need is pressing as treatment of this invasive pathogen has been complicated by the development of antibiotic resistance. One antibiotic resistant phenotype of particular concern is methicillin-resistant S. aureus (MRSA). Due to the multi-drug resistant nature of most MRSA strains, vancomycin emerged as the cornerstone of therapy. Although widely used for serious MRSA infections, many clinicians now question its continued utility due to the emergence of MRSA strains with reduced vancomycin susceptibility phenotypes (rVSPs). The literature is developing rapidly, but characterization …

The Potential For Bridging : Hiv Status Awareness And Risky Sexual Behavior Of Injection Drug Users Who Have Non-Injecting Permanent Partners In Ukraine, Alyona Mazhnaya

Legacy Theses & Dissertations (2009 - 2024)

Abstract

Using Administrative Data To Estimate The Burden Of Chlamydia Among Medicaid Managed Care Enrollees In New York State, Lindsay W. Cogan

Legacy Theses & Dissertations (2009 - 2024)

Infection with Chlamydia trachomatis is of public health concern because of its adverse effects on reproduction. Women infected with Chlamydia can develop pelvic inflammatory disease, which can lead to serious reproductive system morbidity including ectopic pregnancy and infertility.