Mental Disorders Commons^™

Exercise As An Intervention For Postpartum Depression (Ppd), Kylie P. Mistretta

Honors Scholar Theses

Objective: To illustrate the applications of exercise for preventing the development of postpartum depression (PPD) and addressing associated risk factors identified in the literature. Data Sources: PubMed and EBSCO: Academic Search Premier were accessed using the search terms exercise OR physical activity OR yoga AND postpartum depression OR postnatal depression. A secondary search of PubMed was conducted using the search terms exercise AND pregnancy AND depression OR gestational diabetes OR weight gain OR sleep quality.

Study Selection: Studies selected for inclusion were peer-reviewed, published after January 2012, written in English, and relevant to the PPD risk factors examined. Only clinical …

Mechanisms Of Behavioral Change In Hosts Of Toxoplasma Gondii: A Review, Olivia Grimsley

Senior Honors Theses

The parasite Toxoplasma gondii is a highly ubiquitous parasite that latently infects an estimated 33% percent of the global population. Toxoplasmosis is of obvious clinical significance due to the extremely high risks to the unborn who contract it congenitally. Less attention has been given to a more subtle aspect of latent infection, which is the behavioral alterations that are commonly experienced by those who contract the parasite. Infected individuals commonly display a variety of altered behaviors, such as increased aggression and risk-seeking behaviors, depression, higher tendency towards suicide and self-directed violence, a loss of fear response, and a greatly increased …

Investigating Prefrontal Cortex Neuronal Signatures Of Opioid-Induced Risk-Taking Behavior, Cana Quave

Dissertations and Theses (Open Access)

Opioid use disorder occurs alongside impaired risk-related decision-making, but the underlying neural correlates are unclear. We developed an approach-avoidance conflict task using a modified conditioned place preference procedure to study neural signals of risky opioid seeking in the prefrontal cortex, a region implicated in executive decision-making. Following morphine conditioned place preference, rats underwent a conflict test in which fear-inducing cat odor was introduced in the previously drug-paired side of the apparatus. While the saline-exposed control group avoided cat odor, the morphine group included two subsets of rats that either maintained a preference for the paired side despite the presence of …

Evaluating Referral Rates For Positive Postpartum Depression Screenings At Telehealth And Well-Child Visits: A Scoping Review, Rachel Macklin Barber, Mph, Bsn, Rn, Damaris Amber Brooks, Bsn, Rn, Ashli-Emeria Gary, Bsn, Rn, Margaret Harvey, Phd, Acnp-Bc, Chfn, Kate Fouquier Phd, Aprn, Cnm, Pmh-C, Facnm

Doctor of Nursing Practice Projects

Purpose/Background

Postpartum depression (PPD) affects one in nine women. It has distressing impacts, including behavioral and attachment issues and toveruse of healthcare services. PPD occurs within 4 weeks to 12 months postpartum. A scoping review was conducted to compare referral rates to mental health providers after PPD screenings were conducted via telehealth versus those completed at well-child visits.

Methods

Peer-reviewed articles published within five years before the initial search, beginning September 2022 and ending November 2024, were selected. Articles were sourced from several publications using an online library database with various MeSH terms and Boolean operators. Search results were narrowed …

Childhood Trauma Affects Romantic Relationships In Adulthood, Rhianna Vranka

D.U.Quark

Childhood trauma is when a child experiences sexual, emotional, or physical abuse or neglect. Trauma’s causes aren’t limited to just those factors and can result from a variety of experiences. Childhood trauma makes children more vulnerable to developing issues in adulthood because they are at a critical point in their development. There is insignificant knowledge on why childhood trauma affects romantic relationships in adulthood. Knowledge of warning signs and accurate diagnosis is essential to prevent violence stemming from the psychological effects exhibited by those with childhood trauma in relationships. More research is required to understand how to treat the psychological …

The Use Of Person-Centered Language In Scientific Research Articles Focused On Psychosis, Zach Monahan, Tanner Stone, Vinay Swami, Kelly Dunn, Micah Hartwell

Journal of Patient-Centered Research and Reviews

Purpose: Societal stigma of psychosis leads to delayed treatment for individuals experiencing early symptoms, for fear of being labeled “crazy” or “psychotic.” Delayed treatment can worsen the prognosis of individuals with psychosis. Proper adherence to person-centered language (PCL) guidelines can curb the widely held stigmatized preconceptions about psychotic conditions.

Methods: Our meta-epidemiological analysis began with a systematic search of literature in PubMed discussing psychosis from 2020-2022. From the 14,522 results, we randomly selected 500 articles in journals with at least 20 articles on psychosis (n = 9,775), of which 241 articles met the inclusion criteria. These papers were screened for …

Psychopathy And The Media: A Dangerous False Perception, Ashton L. Brophy

Harding Undergraduate Research Conference

Characterized by a lack of remorse or empathy, psychopaths– sufferers of Antisocial Personality Disorder– view the world far differently than the average person. This makes psychopathy an intriguing topic of study. However, many members of the general public lack understanding about the complexities of this disorder due to the false media depictions that make it difficult to accurately identify true psychopaths. By correcting the inaccurate narrative of psychopathy fed to the public through the media, it becomes possible to recognize the responsibility that is to be laid at the feet of the psychopathic offenders who chose violence.

Psychological Treatment Behind The Walls:Insights From The Inside, Rogelio Serrano

Psychology Division Scholarship

Repeated eras of mass incarceration, criminalization of marginalized communities, and substance use policies have created a revolving door of justice involved populations. The ever-increasing prison population has repeatedly become the largest contingency of mental health clientele for an overburdened mental health system. Those who work with formerly incarcerated individuals in the community often don’t know the unique set of challenges faced by practitioners within the system. Increased understanding and coordination of care can offer opportunities for sustained recovery and reduced levels of recidivism. In this presentation participants will learn about the unique insights on mental health treatment that can be …

A New Paliperidone Palmitate Formulation: How Is It Different And Where Does It Fit In Our Array Of Choices For Long-Acting Formulations Of Risperidone And Paliperidone?, Justin Faden, Leslie Citrome

Rowan-Virtua School of Osteopathic Medicine Departmental Research

Long-acting injectable (LAI) antipsychotics have been shown to enhance treatment adherence and outcomes in individuals with schizophrenia, schizoaffective disorder, and bipolar disorder. In recent years, the U.S. Food and Drug Administration (FDA) has approved several LAIs with differing amenities of care, such as mode of administration, duration of oral medication supplementation, dosing frequency, needle gauge and size, and injection volume, amongst others. Additionally, several LAIs are distinct formulations of risperidone and paliperidone, making it difficult to distinguish between formulations, and many providers are unfamiliar with these newer agents. In 2024, a once-monthly LAI formulation of paliperidone palmitate, manufactured by Luye …

The Impact Of Perceived Discrimination On Mental And Physical Health Among The Hispanic Immigrant Population, Cheyla Tabares Cuesta

Undergraduate Theses

Discrimination has profoundly shaped the lives of individuals within disadvantaged communities, but its impact on mental and physical health has often been overlooked. In this project, I review literature on perceived discrimination based on immigrant status and its effects on psychological and physical health and examine a potential mediator and moderator of these relationships. Specifically, the relationships between immigration-based discrimination and both mental health and physical health may be mediated by perceived stress, meaning that discrimination may lead to higher stress levels, which results in poorer health outcomes. Furthermore, these relationships may be moderated by psychological resilience; individuals with higher …

A Long Non-Coding Erna Forms R-Loops To Shape Emotional Experience-Induced Behavioral Adaptations, Rose Marie Akiki

MUSC Theses and Dissertations

Emotional experiences often evoke neural plasticity that supports adaptive changes in behavior, including maladaptive plasticity associated with mood and substance use disorders. These adaptations are supported in part by experience-dependent activation of immediate-early response genes, such as Npas4. We discovered that a conserved, long non-coding enhancer RNA (lnc-eRNA) transcribed from an activity-sensitive enhancer produces DNA-RNA hybrid R-loop structures that support 3D chromatin-looping of the enhancer and proximal promoter and stimulus-induced, rapid Npas4 gene induction. We also show that this Npas4 lnceRNA and its R-loops are required for the development of behavioral adaptations produced by chronic psychosocial stress or cocaine exposure, …

Safety And Efficacy Of 112 Mg Intranasal Esketamine In Patients With Treatment-Resistant Depression: A Retrospective Observational Study From Outpatient Community Clinics, Kirsten Brinkmeier, Michael Kritzer, Brandon Doan, Cecilia Li, Nicholas Mischel

Medical Student Research Symposium

This retrospective study examined the safety and efficacy of 56, 84, and 112 mg intranasal (IN) esketamine via medical record review of 24 patients with treatment resistant depression (TRD). Doses ranged from 56 mg to 112 mg and were titrated across sessions to maximize individual response while considering tolerability. Treatment response was defined by reduction in average Patient Health Questionnaire-9 (PHQ-9) scores. Tolerability was defined by blood pressures at baseline, 40 minutes after, and 2 hours after drug administration. Patients ranged from 19 to 60 years old (average 38.87), and 15 (62.5%) were female. Patients received an average of 1 …

Chronic Alcohol Withdrawal-Associated Increases In Vta Hcrtr1 Expression Are Associated With Heightened Nociception And Anxiety-Like Behavior In Female Rats, Shealan Cruise, Maria E. Secci, Leslie K. Kelley, Nathan M. Sharfman, Keishla Rodriguez-Graciani, Tiffany A. Wills, Nicholas W. Gilpin, Elizabeth M. Avegno

School of Medicine Faculty Publications

Alcohol withdrawal is characterized by various symptoms that include pain and negative affect in the absence of the drug. The neural underpinnings of these behaviors are not entirely understood, but orexin has emerged as a candidate target for the treatment of substance use disorders. Here, we explored changes in orexin system-related gene expression in brain regions important for mediating reward and stress, including the ventral tegmental area (VTA) and extended amygdala (including the central amygdala, nucleus accumbens shell, and bed nucleus of the stria terminalis), in adolescent and adult female Wistar rats following chronic alcohol exposure. We observed higher numbers …

Physiological Indicators Of Social Anxiety In Preschoolers With The Fragile X Premutation, Olivia Cyburt

Senior Theses

The Fragile X premutation (FXpm) is a common genetic disorder often characterized by psychiatric impairments, including anxiety. It results from a trinucleotide repeat expansion (CGG) of 55-200 repeats on the FMR1 gene. Despite its association with psychiatric symptoms, there is limited research regarding the relationship between FXpm and anxiety, particularly social anxiety. Early detection of social anxiety is essential for timely intervention, yet it remains challenging to identify in young individuals with FXpm due to limited research. The present study aimed to bridge this gap by examining social anxiety in preschoolers with the FXpm, utilizing both a physiological and behavioral …

From Theory To Practice: A True-Crime Podcast, Lauren V. Peckham

Senior Honors Projects

The Criminal Element is an innovative, victim-centered podcast that bridges the gap between criminological theory and real-world criminal cases. The podcast is designed as an educational resource for undergraduate Criminology and Criminal Justice students, alongside general audience members interested in learning more about criminological theory. Through the lens of true crime, this podcast is an engaging exploration of foundational and advanced theories while avoiding sensationalism and exploitation, a prevalent problem among true crime media. Each episode connects criminological theoretical concepts – such as strain, social learning, and social disorganization – to contemporary and historical cases, providing listeners with accessible and …

Impacts On College-Aged Asian American Mental Health, Zahra Soherwardy

Senior Theses

This study explores the relationship between different forms of racial harassment and mental health issues in Asian American college students. Asian American mental health is a growing concern in the field of public health. Asian Americans have the lowest treatment rates and some of the highest stigma levels of any demographic. They are also impacted by the model minority myth and discrimination, further alienating them from getting help. The topics of subtle racism, blatant racism, and current racial discrimination were compared to depressive symptoms, anxiety, self-esteem, and four domains of aggression using survey data. Subtle racism was found to be …

Understanding How Family Dynamics Affect Mental Health Communication In Inside Out: A Content Analysis, Kataryna Morton

Honors Program: Senior Projects (Public)

This study examines the impact of open communication between family members on mental health and a child’s sense of belonging in the film Inside Out. Previous research has shown the impact of media on children’s socialization, which can influence stigma and make it less likely for vulnerable communication to occur. It is crucial for children to learn to communicate their emotions, and the media can play a key role in shaping these beliefs. Inside Out provides a positive example of mental health communication, which is specifically explored through Riley’s communication with her parents throughout the film. Using a content analysis, …

Screening For Prodromal Symptoms Of Schizophrenia In Primary Care Settings, Thomas S. Christy

Lynchburg Journal of Medical Science

Schizophrenia is a debilitating mental health disorder with severe and wide-ranging consequences. Early detection of prodromal symptoms (subtle warning signs preceding full-blown psychosis) can significantly improve patient outcomes. Primary care settings, where early intervention is typically most feasible, lack standardized tools to screen for prodromal symptoms of schizophrenia, however. This review examines existing psychosis screening questionnaires to determine their suitability for primary care use. In addition to highlighting the significant role of primary care providers in managing mental health conditions, this review outlines the challenges associated with recognizing early signs of schizophrenia, particularly in resource-limited settings, and therefore why utilizing …

Spirituality And Ptsd Outcomes Among Service Members And Military Veterans, Jennifer Urbina Dmsc, Pa-C

Lynchburg Journal of Medical Science

Post-traumatic stress disorder (PTSD) is a prevalent and debilitating condition among military service members and veterans, often co-occurring with moral injury (MI) and spiritual distress (SD). While conventional PTSD treatments include cognitive behavioral therapy (CBT), exposure-based therapies, and pharmacological interventions, growing evidence suggests that spirituality may play a vital role in improving PTSD outcomes. This paper explores the integration of spirituality in PTSD treatment, examining its potential to mitigate symptoms, enhance resilience, and facilitate post-traumatic growth. Military chaplaincy, spiritually integrated therapies, and Department of Defense (DoD) holistic health models provide frameworks for addressing the spiritual dimensions of PTSD. Studies indicate …

Role Of Eye-Tracking Technology And Software Algorithms In Enhancing Adhd Detection And Diagnosis: A Systematic Literature Review, Lauren E. Perkins

Honors College Theses

This systematic literature review explores the role of eye-tracking technology and software algorithms in enhancing the detection and diagnosis of ADHD. ADHD, a neurodevelopmental disorder affecting both children and adults, is traditionally diagnosed through behavioral assessments, which may lack objectivity. Recent studies suggest that eye-tracking, specifically focusing on saccades, fixations, and blink rates, offers the potential for more accurate and objective measures of ADHD. The review examines clinical trials, observational studies, and machine learning research to assess the correlation between ADHD and eye movement patterns. Results indicate that individuals with ADHD exhibit distinct eye movement patterns, which can be quantified …

Fact Sheet: Ketamine, Aaron Hunt, Gabriela Murza, Jenna Hawks, Alyssa Ferrin

All Current Publications

This fact sheet discusses ketamine, which has pain-relieving properties and has gained recent attention for its antidepressant effects. However, as a Schedule III substance, it has a risk of strong psychological and physical dependence. Recreational use can lead to short- and long-term effects on health and risk of overdose and death.

The Athletes’ Plate: Understanding Influences Of Athletes’ Eating Attitudes, Exercise Behaviors, And Body Image Satisfaction, Delanie Patterson, Brooklynn Raacke, Ryssa Schlaefli

SACAD: Scholarly Activities

Delanie Patterson¹, Brooklynn Raacke¹, and Ryssa Schlaefli²

¹Department of Psychology, Fort Hays State University

²Department of Health and Human Performance, Fort Hays State University

Faculty Sponsors: Brooke Mann¹, Ph.D. and Jessica Phelan², Ph.D.

¹Department of Psychology, Fort Hays State University

²Department of Health and Human Performance, Fort Hays State University

Hays, Kansas

Introduction: Disordered eating (DE), compulsive exercise (CE), and body image satisfaction (BIS) negatively affect male and female athletes. These variables each have a core symptomology but continue to evolve with the increased usage of social …

Narcissistic Personality Indicators As Predictors Of Narcissistic Personality Disorder: A Cross-Cultural Study, Wael M. F. Abuhassan, Brigid Unim, Zulfiqar Ullah Siddiqui, Shaheen Falki, Karavadi Vidusha, Fayez Mahamid, Fakher Nabeel Mohammad Khalili, Kamel H. Katalo

An-Najah University Journal for Research - B (Humanities)

Background: Individuals affected by narcissistic personality disorder (NPD) are characterized by lack of empathy, grandiosity, low self-esteem, and a need for attention and special treatment that leads to unstable interpersonal relationships, occupational problems, and significant psychosocial distress. Objectives: The study aims to evaluate which Narcissistic Personality (NP) dimensions are the strongest and most significant predictors of NPD. Methods: The present study followed a cross-cultural research design aimed at determining the strongest and most significant predictors of NPD, therefore the shortened version of the Narcissistic Personality Indicators (NPI) questionnaire (NPI-40) developed by Raskin and Terry (1988) was administered online to those …

The Unfolding Story Of Protein Misfolding Causing Alzheimer Disease In Recipients Of Human Pituitary Growth Hormone, Evan G. Graber, Sayed M. Hadi Hosseini, Darrell M. Wilson, Alan D. Rogol

Division of Endocrinology, Diabetes and Metabolic Diseases Faculty Papers

Human growth hormone (hGH) has been in clinical use for children with GH deficiency (GHD) since the late 1950s. The original formulations were considered very safe with few adverse events reported. That changed remarkably in 1985 when the first patients with GHD, who had been treated with cadaveric hGH, were diagnosed with Creutzfeldt-Jakob disease (CJD). Fortunately, that same year a robust supply of recombinant hGH was released to the market whose adverse event profile did not include CJD. Patients who had received National Hormone and Pituitary Program hGH have been continuously followed since 1985. It is clear that prions are …

The Development Of Teacher Identity In Counselor Education Doctoral Students, Wes Allen, Joel F. Diambra, Rebecca Gaylor

Journal of Counselor Preparation and Supervision

Abstract

Counselor educators (CE) prepare counselor education doctoral students (CEDS) to work as counselors, scholars, leaders, supervisors, and teachers. While we have a firm understanding of how CEDS develop in general (Limberg et al., 2013; Moss et al., 2014), there is little known about how they develop specifically as teachers. The goal of this research study was to gain insight into how teacher identity develops for CEDS. We interviewed 10 participants using transcendental phenomenology methodology to gain insight into their teaching preparation experiences and identities as teachers. We identified three primary themes from the data: (1) Connection, (2) Confidence, or …

Long-Acting Injectables: A Strategy To Mitigate Nonadherence In Bipolar Disorder, Justin Faden, Elina Maymind

Rowan-Virtua School of Osteopathic Medicine Departmental Research

No abstract provided.

Utilizing Food As An Art Medium In Eating Disorders Treatment, Keren Blumenthal Yanir

Expressive Therapies Dissertations

This research explored food as an art medium in an innovative art therapy intervention for adults with eating disorders (EDs) and what this nontraditional art material can evoke. Several interventions (e.g., food exposure, cooking, and some family-based therapy) incorporate food in ED treatment, but none use it as an art medium.

Six Israeli adults (one with bulimia nervosa, two with atypical anorexia, and three with anorexia nervosa) individually participated in three meetings, each with a 30-min experiential component and an interview. While wearing a GoPro camera, participants created spontaneous artwork using foods (e.g., vegetables, legumes, pasta, flour, candy). The researcher …

Familiarity Of Psychiatric Terms Among College Students, Julia Pekala

CAFE Symposium 2025

Recently, there has been an increase in the usage of psychiatric terminology used among internet users. Terms such as autism, obsessive compulsive disorder, and attention deficit hyperactivity disorder are thrown around without an understanding of these words and their true meaning. These words are picked up and used in a similar context as any other internet lingo, in an ironic, joking manner, without proper consideration of their origins and meaning. Due to most content on the internet being unmoderated and seemingly endless, users are often faced with misleading information about real clinical disorders. The use of these words follows the …

Exploring The Relationship Between Psychiatric Illness And Dermatological Disorders: A Narrative Review, Alan D. Kaye, Rahib K. Islam, Abigayle M. Castine, Grace C. Wester, William T. Barham, Catherine G. Nguyen, Elena Plakotaris, Bradley Dorius, Julian Kim, Patricia Griffin, Amber Edinoff, Sahar Shekoohi, Giustino Varrassi

School of Medicine Faculty Publications

The interplay between psychiatric conditions and dermatological disorders is complex and multifaceted, often resulting in significant challenges for both diagnosis and treatment. This narrative review examines associations between specific psychiatric conditions, trichotillomania, attention deficit hyperactivity disorder, schizophrenia, bipolar disorder, and various dermatological disorders. The present investigation delves into pathophysiological mechanisms, clinical presentations, and management strategies of these comorbid conditions. Psychiatric disorders can exacerbate dermatological conditions through mechanical trauma, medication side effects, and stress-induced exacerbations, while dermatological disorders can lead to significant psychiatric morbidity. The biopsychosocial approach, emphasizing the importance of integrated care involving dermatologists and mental health professionals, is crucial …

A Compelling Case Of The Use Of Electroconvulsive Therapy In Severe Treatment Resistant Depression With Suicidality, Neha Narayanan, Ryan Tam, James Mead

Advances in Clinical Medical Research and Healthcare Delivery

Treatment-resistant depression is a condition that occurs when an individual, experiencing major depressive disorder episodes, has failed the first line of treatment with medication therapy of adequate dose and duration. This is important to be addressed as there is a high likelihood of progression to having thoughts and an intended plan for suicide. Electroconvulsive therapy is a recommended option for those who have failed medication therapy, but it has been controversial in its use due to its stigma and side effects of memory impairment. Here, we present a case of a patient who had undergone several sessions of ECT with …