Open Access. Powered by Scholars. Published by Universities.®
Pharmaceutics and Drug Design Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Institution
-
- New Jersey Institute of Technology (33)
- University of Kentucky (6)
- Old Dominion University (3)
- Virginia Commonwealth University (3)
- The British University in Egypt (2)
-
- University of Texas at Tyler (2)
- Augustana College (1)
- Chapman University (1)
- City University of New York (CUNY) (1)
- Duquesne University (1)
- Fordham University (1)
- Louisiana Tech University (1)
- Portland State University (1)
- Purdue University (1)
- University of Louisville (1)
- University of Nebraska Medical Center (1)
- University of New Mexico (1)
- West Virginia University (1)
- Keyword
-
- Dissolution testing (6)
- Drug delivery (4)
- Microfluidics (4)
- Minimum agitation speed (3)
- Nanoparticles (3)
-
- Retreat-blade impeller (3)
- Baffling conditions (2)
- Biomedicine (2)
- Dissolution profiles (2)
- Drug encapsulation (2)
- Iontophoresis (2)
- Nanomaterials (2)
- Off-center paddle impeller (2)
- Pharmaceutical hot melt extrusion (HME) (2)
- Solids suspension (2)
- 4D DLP Bioprinting (1)
- 4D EPR Imaging (1)
- 4D Extrusion Bioprinting (1)
- AIDS (1)
- Absurdity (1)
- Active pharmaceutical ingredient (API ) (1)
- Agitation speed (1)
- Agitation systems (1)
- Air gap membrane distillation (AGMD) (1)
- Angle-mounted impellers (1)
- Angled-mounted impellers (1)
- Antibacterial agent (1)
- Antibiotic (1)
- Antimicrobials (1)
- Antioxidant Therapeutics (1)
- Publication Year
- Publication
-
- Theses (33)
- Theses and Dissertations (3)
- Theses and Dissertations--Chemical and Materials Engineering (3)
- Electronic Theses and Dissertations (2)
- Nanotechnology Research Centre (2)
-
- Technology Faculty Publications and Presentations (2)
- Theses and Dissertations--Pharmacy (2)
- Biology: Student Scholarship & Creative Works (1)
- Complex Systems Faculty Publications and Presentations (1)
- Department of Medicine Faculty Publications (1)
- Dissertations, Theses, and Capstone Projects (1)
- Doctoral Dissertations (1)
- Electrical & Computer Engineering Faculty Publications (1)
- Graduate Theses, Dissertations, and Problem Reports (ETD) (1)
- Mechanical & Aerospace Engineering Faculty Publications (1)
- Nanoscience and Microsystems ETDs (1)
- Pharmacy Faculty Articles and Research (1)
- Student Theses 2015-Present (1)
- The Summer Undergraduate Research Fellowship (SURF) Symposium (1)
- Theses & Dissertations (1)
- Theses and Dissertations--Neuroscience (1)
- Publication Type
Articles 61 - 61 of 61
Full-Text Articles in Pharmaceutics and Drug Design
Mathematical Modeling Of Transient State Transdermal Drug Delivery, Alison Nickol Weltner
Mathematical Modeling Of Transient State Transdermal Drug Delivery, Alison Nickol Weltner
Theses
In this work, a two-pathway mathematical model for transdermal drug delivery with iontophoresis is presented. The partial differential equations are described and then solved. An alternative, two-pathway, three-layer model is also presented, and the implications of the coefficients within the equation are discussed. Using Franz cell iontophoretic delivery data from three drug substances (amitriptyline HCl, clomipramine HCl, and nortriptyline HCl), the two-pathway model is regressed to determine the diffusion coefficient and the concentration within the skin at the drug reservoir interface. ANOVA analysis indicates a correlation between iontophoretic current and concentration of drug within the stratum corneum.