Medical Specialties Commons^™

A Comparative Study Of Clinical Profile Of Hospitalized Covid-19 Patients In Relation To Their Vaccination Status, Nisha Kaithwas, Garima Agrawal Varshney, Mohit Garg, Piyush Mishra Statistician, Soumitra Sethia

Journal of Medicine in Scientific Research

Background: The clinical picture, outcome of Covid-19 infection and vaccine effectiveness vary in different individuals. These may depend on multiple variables like age, sex, comorbidities, and immune status against the virus and in general. Objective: To describe demography, clinical profile, vaccination status and its impact on clinical outcome of hospitalized Covid-19 patients. Methods: This retrospective study was conducted on hospitalized Covid-19 patients of N.S.C.G.M.C. Khandwa, a tertiary care centre from central India. We studied 188 Covid-19 positive admitted patients’ demographic profile, clinical profile, co-morbidity, vaccination status, clinical outcome and association of these variables to their vaccination status during second Covid-19 …

Standard Median Sternotomy Versus Minimally Invasive Approach For Atrial Septal Defect Closure In Adults, Ahmed S. Ali, Ahmed G. Abd El Fattah Fahmy, Hatem K. Madkour, Reham M. Salah Eldin Ahmed

Journal of Medicine in Scientific Research

Background

Atrial septal defects (ASDs) in adults and adolescents are not uncommon. Surgical ASD closure through a standard median sternotomy (SMS) has become less attractive approach in favor of minimally invasive techniques, especially in young female patients.

Objective

The aim was to compare early postoperative outcomes of surgically closed secundum ASDs through a SMS approach versus minimally invasive right anterolateral thoracotomy (MIRAT) approach in adults.

Patients and methods

The authors prospectively studied 60 adult patients who had their secundum ASD anomalies surgically closed at National Heart Institute between the period of September 2020 and February 2022. A total of 30 …

Forced Expiratory Volume In The 6 S And Forced Expiratory Volume In The 1 S/Forced Expiratory Volume In The 6 S For Early Detection Of Airflow Obstruction, Therese S. Ghatas, Moheb W. Elfaizy

Journal of Medicine in Scientific Research

Introduction

Use of affordable and simple tools for screening chronic obstructive pulmonary disease (COPD) is limited. In recent years, measurement of forced expiratory volume in the 6 s (FEV6) has been researched as a substitute to replace forced vital capacity measurements. This work was performed to analyze the effectiveness of a simplified handheld forced expiratory flowmeter device and to search an optimal cutoff value of FEV1/FEV6 to detect airflow narrowing and limitation.

Patients and methods

This was a cross-section study for screening and finding of active case among undiagnosed patients with COPD using a simple handheld spirometry device, and the …

Assessment Of The Right Ventricular Function Before And After Coronary Artery Bypass Surgery By Conventional And Tissue Doppler Echocardiography, Emmanuel L. Aziz, Mohamed Abbas, Ashraf Abd-Elaziz, Wayel S. Bebawy

Journal of Medicine in Scientific Research

Aim of the work To study the extent of right ventricular (RV) dysfunction in ischemic patients after coronary artery bypass grafting (CABG). Patients and methods RV function was studied preoperatively and followed for 1 month postoperatively in 40 patients who were scheduled for elective coronary artery bypass surgery and in other 40 controls. We evaluated RV function by tissue Doppler study of the tricuspid annulus and the basal septum, tricuspid annular plane systolic excursion, and RV dimensions. Both LV dimensions, left atrium dimensions, and aortic root dimensions were also measured before and after surgery. Results RV function was significantly reduced …

Mortality Rate Among Preterm Infants With Respiratory Distress Syndrome On Non-Invasive Respiratory Support (Nirs): A ٌRetrospective Multicenter Study, Abeer E.S. Hamed, Alaa A. Rashad, Manar A. El Desouky, Mahmoud H. Dawabah, Mohamed M. A. Shaheen, Heba Allah M. Sherief, Mohamed A. Ibrahim, Sohaila A Abd El-Halim

Journal of Medicine in Scientific Research

Background: Neonatal acute respiratory distress is a common cause for mortality and morbidity in preterm neonates. Non-invasive ventilation is crucial for preterm neonates, nasal intermittent positive pressure ventilation and nasal continuous positive airway pressure. Recently, heated humidified high-flow nasal cannula modes have been revealed as more efficient non-invasive ventilation mode in improving functional residual capacity however, other studies have questioned its efficacy and safety in comparison to other non-invasive ventilation. Many studies have investigated the common predictive factors that are associated with intubation and failure of spontaneous breathing. Consequently, this study aimed at investigating the common factors associated with prolonged …

Molecular Detection Of Entamoeba Histolytica In Diarrheic Fecal Samples From Patients Attending National Hepatology And Tropical Medicine Research Institute, Azza Hasan Abbas, El Shahat Ahmed Elshahat, Heba Mohamed Abdelglil

Journal of Medicine in Scientific Research

Background: Amoebiasis is a worldwide disease caused by Entamoeba histolytica infection. The true prevalence is unknown due to the difficulty in distinguishing Entamoeba histolytica from non-pathogenic amoebas especially when microscopic diagnosis is performed, to overcome microscopy misidentification. Polymerase Chain Reaction (PCR) assay is necessary as a highly sensitive and specific technique. Objective: To determine the value of Real-Time PCR (RT.PCR) in the diagnosis of Entamoeba histolytica in the stool samples of diarrheic patients attending NHTMI versus microscopy, copro- antigen, and serum antibodies detection techniques. Subjects and Methods: A cross-sectional study was conducted on 150 diarrheic patients. Their stool samples were …

Comparison Of Loss Of Resistance Syringe Technique Versus Balloon Technique For Identification Of Epidural Space: A Prospective, Randomized Controlled Study, Isha Singha, Gayatri Vadaratti, R.D. Patel

Journal of Medicine in Scientific Research

Context Epidural anaesthesia has an important role in modern anaesthetic practice due to its safety and efficacy, and its success depends on the technique used for identification of epidural space. Aims: In this study we compared the of loss of resistance (LOR) technique versus the balloon technique for identification of the epidural space in terms of number of attempts and time taken. Also the efficacy of the two techniques in the hands of experienced and inexperienced anaesthesiologists was compared and complications noted. Settings and design Tertiary care hospital. A prospective randomized controlled study. Methods and material 164 ASA I and …

The Immune Response To Long Term Administration Of Dipravan Compare To Dormicum In Surgical Care Unit, Ashraf Abd El Hameed Soliman, Wael Abd Elateif El Hakeem, Raghad S. Abdellatif

Journal of Medicine in Scientific Research

Introduction : - Immune response may be affected by anesthesia and sedation. In anesthesia, the immue response is temporary as anesthesia is used for short time. However, the immune response more obvious in critical illness patients because of long time of sedation. Diprivan and dormicum are two commonly used medications for sedation and analgesia in critical care unit patients. Dipravan is a good medication for sedation in the surgical care unit. Dormicum in the surgical care unit, usually producing prolonged time of sedation when used for long time in surgical care unit. Patients and methods: - This article was done …

The Relation Between Heart Rate Response During Exercise And Angiographic Severity In Patients With Chronic Coronary Syndrome, Emmanuel Louka

Journal of Medicine in Scientific Research

Introduction Ellestad and colleagues, in 1975, reached to the conclusion that impaired heart rate response to exercise carries a similar risk for future coronary events such as ischemic ‘ST’ segment changes. Mc Neer and colleagues went beyond these observations to include a survival benefit in patients who achieve a higher peak heart rate (PHR), a more advanced level of exercise, and have a normal exercise electrocardiogram. Aim The aim of this work is to clarify the relation between the chronotropic response to exercise and the severity of coronary artery disease in patients with chronic coronary syndrome. Patients and methods The …

Effect Of Empagliflozin Metformin With Clomiphene Citrate Versus Metformin With Clomiphene Citrate On Cases Of Polycystic Ovary Syndrome, Diaa Shams Eldin El Gohary, Mohammed Mohammed Ismail, Ahmed Mahmoud El Khayat, Sherin Barakat Elbohoty

Journal of Medicine in Scientific Research

Background: Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women of reproductive age associated with long-term metabolic and cardiovascular consequences. Aim and objectives: In this research, we aimed to assess the impact of Empagliflozin Metformin with Clomiphene Citrate versus Metformin with Clomiphene Citrate on weight reduction and its impact on folliculometry and ovarian volume in cases of Polycyctic Ovary Syndrome. Subjects and Methods: This was a randomized clinical trial; in which 150 Patients were being randomly assigned into two equal groups; Group A: 75 cases received empagliflozin metformin 12.5/500 mg Continously once daily plus clomiphene citrate 50 mg …

Comparative Study Between Intravenous Anesthesia (Propofol) And Inhalational Anesthesia (Sevoflurane) On The Cytokine’S Response To Abdominal Operation, Ashraf A.H. Mahmoud Soliman, Maisa M. Abdel Khalik, Wael A.E. El Hakeem, Raghad S. Abdellatif

Journal of Medicine in Scientific Research

Introduction These days, the need for more information and familiarity with the inflammatory response to different anesthetic drugs increase. Not only some patients suffering from immune reactions against some anesthetic drugs, but all surgical patients are liable to decrease in immunity postoperatively. This may increase the postoperative morbidity and mortality, affects healing, and spread of tumors postoperatively. This decrease in immunity is due to surgery trauma causing imbalance in cytokine response. Patients and methods This article was written on 40 patients, and patients were randomly classified into four equal classes. Class A: inhalational anesthesia on major operation. Class B: intravenous …

Comparative Assessment Of The Efficacy Of Onabotulinumtoxina As Monotherapy And Combined Therapy With Propiverine In Female Refractory Overactive-Bladder Syndrome, Abourjila A. Gamal Eldin, Ayman M. Gabr, Amr M. Elsofy

Journal of Medicine in Scientific Research

Objectives The aim of the study was to compare the efficacy of onabotulinumtoxinA and anticholinergic popeverine in adult females. This is a placebo-controlled study. Introduction The active ingredient, propiverine hydrochloride, blocks muscarinic receptors with a slightly higher affinity for the M3 as compared with the M2 subtype. In addition, it inhibits calcium influx and modulates intracellular calcium in the bladder smooth-muscle cells, which then leads to musculotropic spasmolysis. Patients and methods Between 2015 and 2019, 94 patients received intravesical onabotulinumtoxinA for the treatment of refractory idiopathic detrusor overactivity after its introduction into the Department of Urology of our National Institute …

Effectiveness Of Management Program Of Chronic Functional Constipation In Children Who Are Attending The Pediatric Gastroenterology Clinic At Elbeheira Specialized Children's Hospital, Hamouda E. El-Gazzar, Sabreen Ahmed Ali Elsaka, Eman Adel Elsaid Elhaddad

Journal of Medicine in Scientific Research

Background: A chronic constipation is one of the most common functional gastrointestinal complaints in pediatric outpatient clinics. The prevalence of childhood constipation in the general population ranges widely from 0.7% to 29.6% internationally. Pediatric Gastroenterology Clinic at Elbeheira specialized children's Hospital is a referral center from the whole governorate. Objectives: To evaluate the current approach to management, risk factors associated, and clinical characteristics, the challenge of functional constipation in the pediatrics who are attending the Pediatric Gastroenterology Clinic at Elbeheira Specialized Children's Hospital. Methods: This retrospective study was conducted in Pediatric Gastroenterology Clinic at Elbeheira Children's Specialized Hospital for 6 …

Endovascular Management Of Vein Of Galen Aneurysmal Malformations: Case Series And Review Of The Literature, Mohammed A. El-Din Habiba, Sameh M. Saleh

Journal of Medicine in Scientific Research

Background Neonates with vein of Galen aneurysmal malformations (VGAMs) who present with heart failure have a high rate of morbidity and mortality, while those who present later in childhood have considerably better outcomes. Aim To determine the factors that have the greatest predictive value in predicting long-term results in children with VGAM. Patients and methods Between June 2015 and June 2020, 15 patients (seven infants, eight children) were diagnosed with symptomatic VGAMs, four of whom were suffering from intractable high-output heart failure and received initial endovascular treatment. All of them were treated by endovascular procedures. Staged transarterial route was the …

Different Modalities Of Tongue Tie Management, Wesam Ibrahem Homouda, Esayed Hussien Elmokadem, Mohamed Amr Hamdy Salem

Journal of Medicine in Scientific Research

Background: Tongue-tie or ‘ankyloglossia’ is a congenital anomaly characterized by presence of an abnormally tight lingual frenulum - a string like membrane – that attaches the tongue to the floor of the mouth. It affects the movement of the tongue. For symptomatizing ankyloglossia surgical treatment with different surgical techniques such as (Frenotomy, frenectomy/frenulectomy, and frenuloplasty) is the treatment of choice that gives satisfactory results. Objectives: We built our study to compare between different surgical techniques used for management of ankyloglossia. Patient and method: in our study 60 patients were included 33 were female and 27 were male with age ranging …

A Case Of Congenital Diaphragmatic Hernia Presenting In The Adult As Gastric Volvulus, Sajal Gupta, Ismail Khan, Indu B. Dubey, Mayank Verma

Journal of Medicine in Scientific Research

We report a case of an adult patient who was referred to the surgical emergency for the evaluation of acute abdominal pain and vomiting. Radiograph chest showed a left-sided cavity, which was misleading to lung pathology. A suspicion of gastric volvulus was kept in mind on seeing the stomach in the radiograph. Computed tomography confirmed the diagnosis of diaphragmatic hernia. The insertion of the Ryle’s tube corrected the gastric volvulus. An immediate laparotomy was done for the closure of the diaphragmatic gap and reduction of the herniated contents. The patient responded well and was discharged in a week.

Complete Dorsal Pancreatic Agenesis: A Case Report, Ritish Gupta, Ashima Mittal, Bhavna Arora, Riya Aggarwal

Journal of Medicine in Scientific Research

Complete agenesis of the dorsal pancreas (ADP), an extremely rare congenital anomaly, is caused as ‘the dorsal pancreatic bud fails in developing the body and tail of the pancreas at the time of embryological development.’ There are nearly 100 cases of dorsal pancreatic agenesis till date. Most of the individuals with ADP are without symptoms; however, few may present with clinical manifestations like pancreatitis, epigastric pain, hyperglycemia, and diabetes mellitus. This is a case report of a 19-year-old female with ADP, who was diagnosed incidentally while undergoing radiological assessment for abdominal pain in left hypochondrium. As complete ADP is very …

Role Of High-Resolution Ultrasonography And Electromyography In The Evaluation Of Patients With Flat Foot, Mai M. Kamel, Ahmed Abdelrahman Elatreby, Amr M. Gamil, Gamal Salah Eldin Elmorsy

Journal of Medicine in Scientific Research

Objective: The present work aimed to assess the abductor hallucis (AH) muscle changes using sonographic and electrophysiologic studies in flatfoot patients. Patients and methods: This study included 60 patients with flatfoot deformity (group I) and 20 age and sex-matched healthy individuals as a control group (group II). The patients were subjected to full history taking, clinical assessment, foot x-ray examination, high-resolution ultrasound, and surface electromyography (EMG) of AH muscle. Using a plain x-ray, Meary's angle was measured, and severity grading was categorized for the patient group. Results: The AH ultrasonography revealed a significant difference between patient and control groups regarding …

Community-Acquired Pneumonia Among Hospitalized Children: Risk Factors, Characteristics, And Outcomes, Marwa Taha, Hanaa Abdel-Wahab

Journal of Medicine in Scientific Research

Background Community-acquired pneumonia (CAP) represents one of the main causes of mortality and morbidity among under-five children worldwide. More than 75% of these fatalities are caused by severe pneumonia. Objectives to identify the potential risk factors associated with severe CAP among under-five children hospitalized with CAP. Patients and Methods This prospective observational study was conducted on children, aged 1 to 59 months, who were admitted with CAP to the Department of Pediatrics, Mataria Teaching Hospital, Egypt. Based on World Health Organization (WHO) guidelines, patients were classified into two groups; CAP and severe CAP. Data including demographic, children's history, clinical assessment, …

Vestibular Assessment In Patients With Temporomandibular Joint Dysfunction Attending Otolaryngology And Oral Medicine Outpatient Clinics, Sanaa Mahran Mohamed Andeil, Zienab Shalaby Farid Shalaby, Anwar Moawad Elbatawy

Journal of Medicine in Scientific Research

Introduction: Temporomandibular joint dysfunction (TMD) is caused by inflammation of the ligaments and muscles surrounding the joints. TMD is associated with several comorbidities, one of these comorbidities are otological problems. The otological symptoms related to TMD are tinnitus, otalgia, ear fullness, and Vertigo. Vertigo is observed in many diseases and etiologic factors should be investigated to increase the efficiency of treatment Objective Here we assess VNG and cVEMP findings in patients with TMD via objective vestibular testing tools including VNG and cVEMP recordings. Here, we compare findings of cervical vestibular evoked myogenic potentials (cVEMP) and of the caloric test, to …

The Predictive Ability Of Interleukin-6 For Infection After Major Surgery, Naser T. Elshamy, Salama M. Elshennawy, Mahmoud A. Donia

Journal of Medicine in Scientific Research

Objective The aim was to evaluate the role of interleukin (IL)-6 in prediction of infection after major surgeries. Background An early sensitive and specific marker for postoperative infection would be of interest. The cytokines such as IL-6 and IL-10 have been shown to relate to the severity of postoperative sepsis and patient outcome. Patients and methods The study was conducted prospectively at Shebin Elkom Teaching hospital in the period from January 2015 to October 2016 on 50 consecutive patients undergoing elective major surgical procedures. Septic complications were recorded for 4 days postoperatively. For evaluation, patients were allocated into two groups …

Assessment Of Carotid Intima-Media Thickness And Its Relation To Cardiovascular Risk Factors In Obese Children, Faten A.A. Fathi, Somaya M. Abd El Ghany, Ahmed A.H. Taha, Gihan F.A. Hassan, Eman Fouad

Journal of Medicine in Scientific Research

Background Childhood obesity is one of the most critical public health problems today. This study aims to assess the relation between carotid intima-media thickness (CIMT) and cardiovascular risk factors in obese children. Patients and methods This is a case–control study conducted on 80 Egyptian children aged 6–18 years; 40 children with simple obesity as defined by WHO (2011) and 40 healthy children age matched and sex matched were taken as a control group. Cases were selected from the National Nutritional Institute randomly from December 2017 to March 2018. All patients and control groups were subjected to the following: full history …

Auditory Temporal Processing Abilities In Patients With Diabetes Mellitus Type 1 And Type 2, Abir Omara, Sanaa Mahran, Heba Ramadan

Journal of Medicine in Scientific Research

Introduction: Diabetes mellitus is most common chronic disease characteristic by carbohydrate metabolic disorder in which absolute or relative deficiency in insulin and various pathological changes in the body system. The central nervous system disorders is among system affected by toxic effect and hyperglycemia. Auditory temporal processing is one of the important abilities of the central nervous system which may be affected by diabetes. However, the extent and nature of the central manifestations are still unknown. Objective: The aim of this study was to compare auditory temporal processing in these patients (Diabetics type 1 and Type 2) with normal subjects through …

Outcome Of A Case Of Living Donor Kidney Transplant With High Levels Of Pre-Transplant Donor Specific Antibodies, Ahmed Hassan Elthakaby, Aza Elmenyawi

Journal of Medicine in Scientific Research

For patients with ESRD, kidney transplant offers significant survival and quality-of-life advantages compared with dialysis. Non-sensitized renal transplant recipients when compared to patients with preformed alloantibodies, the latter are at greater risk of cellular, humeral rejection and premature graft failure. In this paper we will present a successful case of young adult who has ESRD and maintained on regular hemodialysis and undergo live related renal transplant with high dose HLA class I and class II antibodies and negative cross match by CDC and flow cytometry.

Prediction Of Response To Disease-Modifying Therapy In Multiple Sclerosis, Abdelrahman M. Abdalla, Azza Abd El-Nasser, Mohamed Fouad, Mahmoud S. Swelam

Journal of Medicine in Scientific Research

Background Multiple sclerosis is an idiopathic inflammatory disease of the central nervous system and the second most common cause of disability in young adults. Choosing an effective treatment is crucial to preventing disability. Aim To identify predictors of disease-modifying therapy (DMT) after 1 year of treatment. Patients and methods In this retrospective study, 150 patients with confirmed diagnosis of relapsing-remittent multiple sclerosis were recruited from the MS Unit at the Neurology Departments from both Ain-Shams University and Cairo University Student Hospital. All of the study population received either interferons or fingolimod. Modified Rio score was used to classify patients to …

An Observational Study Of The Association Of Preoperative Mri Findings And Intraoperative Findings In Patients With Fistula In Ano, Tushar Sharmaa, Nabal K. Mishra, Shyam Lal, Tanweer Karim, Rahul Rohitaj, Gaurav Patel

Journal of Medicine in Scientific Research

Objective To assess the precision of preoperative MRI pelvis for identification of anal fistulas with regard to intraoperative findings. Patients and methods A prospective observational cohort study was done in the Department of General Surgery, over a period of 18 months (October 2019–April 2021) during which all diagnosed cases of fistula in ano admitted for elective surgery were included and operated by an experienced surgeon. MRI and clinical evaluation were done preoperatively and correlated with intraoperative findings. Patients were followed up for 12 weeks during which recurrence and complications were noted. Results The mean age of the patients was 36.98 …

An Analytical Study Of The Risk Factors Affecting The Platelet Aggregation In Patients With Sepsis, Vishnu Priya, Jitender M. Khunger, Anupma Arora

Journal of Medicine in Scientific Research

Objectives (a) To determine the correlation of platelet count and aggregation with sepsis severity and (b) to find the risk factors affecting the platelet aggregation in sepsis. Patients and methods The present observational cross-sectional study was conducted on 30 patients of sepsis over a period of 18 months. All patients underwent complete blood counts, and platelet aggregation to ADP. Pearson correlation coefficient was used to assess the association of Sequential Organ Failure Assessment (SOFA) score and aggregation to ADP and platelet. Linear regression was done to determine the risk factors affecting platelet aggregation in sepsis. A P value of less …

Comparative Study Between Radiofrequency Ablation And Endovenous Laser Ablation In The Management Of Primary Great Saphenous Varicose Veins, E.M Reem, H.T Ahmed, A.A Mohammed, H.A Mohamed

Journal of Medicine in Scientific Research

Background: Varicose veins are a common presentation of chronic venous disease. Multiple risk factors have been specified by epidemiological studies such as female sex, pregnancy, obesity, and prior deep venous thrombosis. Objective This is a prospective, comparative study to compare radiofrequency (RF) ablation versus endovenous laser ablation (EVLA) in the management of primary varicose veins of great saphenous vein (GSV). Patients and methods This study was conducted to 130 patients who had primary great saphenous varicose veins who attended to the vascular department of Ain Shams University Hospitals and El-Sahel Teaching Hospital. The study is a prospective comparative clinical trial. …

A Comparison Of Robotically Assisted Needle Guidance Via The Piga Ct System And Conventional Ct For Percutaneous Lung Biopsies, Virender Malik, K Uday Bhanu, Dhanalakshmi B

Journal of Medicine in Scientific Research

Objective

The aim was to compare the speed, radiation exposure, needle adjustments, diagnostic efficacy, and complication rate using manual guidance and robotically assisted needle guidance via the PIGA computed tomography (CT) system for percutaneous lung biopsy.

Methods

A randomized interventional trial was conducted from September 2020 to March 2021 on 30 patients requiring lung biopsies for suspected malignancy. Random allocation of the 30 patients was done in group A (robot-assisted CT scan) and group B (conventional manual CT scan). The outcomes were compared with respect to the total procedural duration, time taken in the navigation of needle insertion, needle manipulations, …

Repair Vs. Conservative Treatment For Ischemic Patients With A Moderate Degree Of Mitral Incompetence, Ahmed Shafeek Ali, Mohamed Belal Mohamed Abd Elbaki, Haitham Alshahat Ramadan, Reham Mohammed Salah Eldin Ahmed

Journal of Medicine in Scientific Research

Background: Ischemic heart diseases are often associated with a moderate degree of mitral incompetence. The optimal treatment of this condition is still controversial. benefits of repairing moderate mitral incompetence in ischemic patients are uncertain. Objectives: compare outcomes of treating ischemic patients with moderate mitral incompetence either by isolated CABG versus CABG with mitral repair. Patients and methods: We prospectively studied 60 consecutive ischemic patients with a moderate degree of mitral incompetence who were surgically treated at the National Heart Institute between the period of April 2021 to March 2022. 30 patients had isolated CABG surgery while the other 30 patients …