Medical Specialties Commons^™

Role Of Progesterone And Inhibin A In Predicting The Adverse Outcome Of Pregnancy, Ahmed Hassan Khedr, Amany Seif Mohammed Soliman, Yasmine M. Amrousy, Shaimaa Elsayed Belal

Journal of Medicine in Scientific Research

Background: The prediction of future miscarriages in patients who have had a first-trimester abortion can be improved by measuring levels of inhibin A and progesterone. Pregnancy outcomes can be improved by using this important information to direct clinical treatment and care Objective. Progesterone and Inhibin A during the first trimester can be used to quickly and precisely detect pregnancy outcomes, improving prenatal services. Methods: A total of 180 women from Badr City Hospital participated in the study, split up into two groups: group b contained ninety women who had undergone a first-trimester abortion, and group a comprised ninety well-being expectant …

One-Year Single Center Initial Experience Of Supine Pcnl, Alaa Ali Mousa, Fayez El Askari, Abdelhamid Khattab

Journal of Medicine in Scientific Research

Objectives: to study the safety and efficacy of supine position in percutaneous nephrolithotomy in treatment of large renal stones. Methods: A retrospective study included 51 patients with large renal stones (more than 2 cm) planned for PCNL operation underwent percutaneous nephrolithotomy (PCNL) in modified flank supine position from October 2022 till August 2023. We excluded from this study as uncorrectable coagulopathy, active urinary tract infection (UTI), and pediatric patients, younger than 18 years. The study protocol was approved by Damanhur National Medical Institute (HD000188/22/11/2023). Results: The most common site of stone was renal pelvis in 17 cases (33.3%) then stag …

Facial Nerve Palsy: A Usual Clinical Presentation In The Post-Covid Patients With Mucormycosis, Anwar Moawad Elbatawy, Ahmed Mohamed Mostafa, Tareq Abdul Ghani, Amr Elshafey, Ahmed Abou El Fotouh, Elham Mohamed Mostafa, Mohammad Mostafa Gaballah

Journal of Medicine in Scientific Research

Background: Mucormycosis emerges as a severe fungal infection in the post-covid uncontrolled diabetic patients with a history of steroid therapy. Facial palsy coexists in these patients due to mucormycosis. We aim to study the prevalence of facial palsy in these critical patients. Methods: we design a retrospective cross-sectional study for 26 patients admitted to El-Gomhorea teaching hospital to assess the prevalence of facial palsy among this group. Results: 46.2% of diabetic post-covid patients present with facial nerve paralysis. We observed the clinical significance of facial palsy among different age groups. Conclusion: facial nerve palsy has become a usual clinical presentation …

Surgical Radiofrequency Ablation Using The Left Modified Maze Procedure In The Treatment Of Chronic Atrial Fibrillation During Mitral Valve Surgery – Early Results, Ahmed A Faragalla, Ahmed M Elshiemy, Sherif A Elhendawy, Ahmed A. Abdelhamid

Journal of Medicine in Scientific Research

ABSTRACT Background: Complex Cox-Maze III is standard for atrial fibrillation in mitral valve surgery. Radiofrequency ablation, a newer energy-based method, might be simpler and less risky. Aim of the work: Assessing the Efficacy of Surgical Radiofrequency Ablation for Chronic Atrial Fibrillation with Left Atrial Modified Maze Procedure in Mitral Valve Surgery. Patients and Methods: A randomised controlled study (80 patients, mitral valve disease + chronic atrial fibrillation) compares a left-modified Maze with radiofrequency ablation (Group A/40) vs. mitral valve surgery alone (Group B/40) at the National Heart Institute—primary outcome: Restoration of sinus rhythm. Results: This randomized controlled study (n=80, mitral …

Predictors Of Residual Vsd After Surgical Versus Transcatheter Closure, Ramdan Ibrahim Mohammed Ouf, Deyaa Ahmed Abdallah Mohamed

Journal of Medicine in Scientific Research

Background: Ventricular septal defect (VSD) repair is a frequently performed cardiac procedure in children, and it is associated with a extremely low likelihood of experiencing post-operative complications. Aim of the study: to identify the incidence of residual shunt across interventricular septum after surgical repair or device closure of isolated VSD or associated with another congenital anomaly. Methods: This is a retrospective study included 60 patients undergoing closure of VSD between January 2021 and January 2023 in National Heart Institute. They were divided into 2 groups: Group I underwent surgical closure (30 patients) and group II underwent transcatheter closure (30 patients). …

The Effect Of Different Types Of Phacoemulsification Surgery On The Postoperative Visual Acuity, Tarek Ibrahim Badr

Journal of Medicine in Scientific Research

Background

The most popular cataract surgery method in the world is phacoemulsification surgery. There are two kinds of phacoemulsification: longitudinal and torsional. Our research compares the impact of longitudinal and torsional phacoemulsification on postoperative visual acuity.

Patients and Methods

We will compare the postoperative best-corrected visual acuity (BCVA) after torsional phacoemulsification against longitudinal phacoemulsification in our prospective randomized trial. Fifty eyes having cataract of nuclear shape ranging in grade from grade 1 to grade 3 going to be involved in our study.

Results

Regarding postoperative visual acuity, the P-value between torsional phaco and longitudinal phaco was 0.557 (> 0.05), indicating …

The Effect Of The Primary Wound Closure Technique In The Surgical Treatment Of Closed Intra-Articular Calcaneal Fractures, Mohamed M. Abd El-Monem Gafar, Ashraf Hassen M. Mohammed, Ahmed A. Elseadawy, Mohamed Salah Labib

Journal of Medicine in Scientific Research

Aim: To assess the impact of the primary wound closure method in the surgical management of closed intra-articular calcaneal fractures, with the aim of improving postoperative wound healing, reducing complications, minimizing expenses, enhancing overall functional outcomes, and restoring foot function and patients' quality of life. Design: Our study, a prospective and retrospective cohort clinical study, was conducted in our hospitals. Patients and Methods: Twenty-eight patients with thirty-one intra-articular calcaneal fractures were enrolled, following stringent inclusion and exclusion criteria for patient selection. These patients underwent open reduction using an extensile lateral approach and internal fixation with plates and screws at our …

Clinical Study Of Combined Arthroscopic Drilling And Platelet Rich Plasma Injection In Knee Osteochondral Lesions In Middle-Aged Patients, Mohamed Salah Labib Mohamed, Mohamed Abd Elmoneam Gafar

Journal of Medicine in Scientific Research

Background: Osteochondral lesions commonly occur in the knee joints and causes detrimental effects on the quality of life. Arthroscopic drilling is the treatment option for mild to moderate lesions. However, it is debatable whether regenerated cartilage from arthroscopic drilling surgery is durable. It is speculated that induction of chondrocyte differentiation from subchondral mesenchymal stem cells is facilitated by platelet-rich plasma (PRP), which is a rich source of diverse growth factors.

Aim of work: To evaluate the procedures of combined arthroscopic drilling and PRP injection intra-articularly for mild to moderate knee osteochondral lesions management.

Patients and Methods: This randomized prospective study …

Safe Monsplasty Technique Combined With Abdominoplasty, Ebrahim Awad Rizk, Maurice Fekry Khalil

Journal of Medicine in Scientific Research

Background: One of the most common procedures for changing the shape of a person's body is abdominoplasty, which often includes monsplasty. It is one of the top five procedures in cosmetic surgery. Abdominoplasty and body lift operations may begin with a monsplasty. Here, we detail a novel method for treating pubic deformities triggered by massive weight reduction.

Aim and objectives; The purpose of this research was to evaluate how happy our patients were with the results of their monsplasty and abdominoplasty procedures following significant weight loss. Our team also tried to develop a surgical care decision-making system.

Subjects and methods; …

Detection Of Cardiac Involvement Using Speckle Tracking Echocardiography In Covid-19 Recovered Patients And Its Relation To Leucocyte Count., Shaimaa Wageeh, Eman H Seddik, Alaa Ramadan Youssuf

Journal of Medicine in Scientific Research

Background: Globally, the coronavirus disease-2019 (COVID-19) pandemic remains a leading cause of morbidity and mortality. Our research aimed to assess the relationship between recovered COVID-19 patients' left ventricular (LV) systolic function and a range of inflammatory and hematological markers

Methods: For cases; baseline clinical and biochemical data such as the complete blood count (CBC), serum ferritin, C-reactive protein (CRP), lactate dehydrogenase (LDH), and D-dimer were measured Echocardiographic parameters of left ventricular (LV) functions, including global longitudinal strain (GLS), myocardial performance index (MPI), left atrial volume index (LAVI), and ejection fraction, were done to all cases and controls.

Results: GLS was …

The Value Of Neutrophil, Platelet-To-Lymphocyte Ratio And Lymphocyte To Monocyte Ratio With Disease Activity In Rheumatoid Arthritis, Lamis Safwat, Shaimaa Mohamed Abd El Aziz

Journal of Medicine in Scientific Research

For rheumatoid arthritis (RA) patients, altering their disease activity is crucial to their treatment plan. Utilising the platelet/lymphocyte ratio (PLR), neutrophil/lymphocyte ratio (NLR), and lymphocyte/monocyte ratio (LMR) as indicators of inflammation as a result of inflammatory process that led to alteration in platelets, neutrophils, monocytes, and lymphocytes absolute number. We aim to provide an overview of the most recent research on the diagnostic potential of three systemic inflammatory ratios as indicators of rheumatoid activity:), platelet/lymphocyte (PLR), neutrophil/lymphocyte (NLR) and lymphocyte/monocyte (LMR) . We concentrated on the research that evaluated blood cell parameters' diagnostic usefulness depending on the ROC ie area …

Effect Of Covid 19 On Pre-Existent Hypertension And Its Impact On Unmasking New Onset Hypertension In Recovered Cases: A Single Center Experience, Devang Kulkarni, Shital Patil, Anant Kulkarni, Gajanan Gondhali

Journal of Medicine in Scientific Research

Introduction New onset hypertension and aggravation of hypertension during the post-COVID period are issues of concern having very limited data published on them. Hence, the current study was conducted with the aim of studying the blood pressure profiles as new onset hypertension, preexistent hypertension and an aggravation of preexistent hypertension in post-COVID patients. Methods Retrospective cohort study conducted between October 2021 to March 2022, included 800 post-COVID patients above 18 years of age treated at the DCC (dedicated covid care center) irrespective of their disease severity and comorbidity after a valid written consent. All the study cases were followed after …

Evaluation Of Iron, Zinc And Vitamin D Deficiencies In Children With Autism Spectrum Disorder At The Hearing And Speech Institute, In Egypt, Azza Samy, Iman Elrouby, Eman S. Eldin, Eman S. Abd El-Ghaffar

Journal of Medicine in Scientific Research

Background Autism spectrum disorder (ASD) is a complex neurodevelopment disorder with a multifactorial etiology. Each iron, zinc and vitamin D are essential for cognitive, behavioral and motor development. Deficiency of any of these micronutrients may affect ASD symptoms.

Objective The aim of this study is to evaluate and compare the level of iron, zinc and vitamin D levels in children with autism spectrum disorder (ASD) with normal children and to associate between the deficiency of these nutrient elements and the severity of ASD symptoms, in order to help in improvement of ASD symptoms by supplying the deficient elements.

Patients and …

Inter-Reader Agreement And Accuracy Of O-Rads Mr Risk Stratification System In Assessment Of Adnexal Lesions, Mena Elerian Youssef Ekladious, Jehan Ibrahim M. Altohamy, Rania Hassan Mostafa Ahmed, Suzan Farouk Ibrahim Salib, Shrouk Mohamed Awadallah

Journal of Medicine in Scientific Research

Background Ultrasound is the initial modality employed to investigate adnexal lesions due to its high sensitivity and specificity in excluding malignancy when classic benign characteristics are observed. Nevertheless, the positive predictive value (PPV) of cancer can vary from 7% to 50% when a lesion has indeterminate imaging features in the US, and the PPV for cancer can range from 29% up to more than 50% when a lesion exhibits characteristics that are concerned for malignancy. (2). MRI has the capacity to enhance the PPV from cancer to 71%, with a negative predictive value of 98%. (3). The MRI's ability to …

Factors Affecting Non-Compliance With Treatment Among Diabetic Students At Sohag University, Rasha Gamal-El-Din Abu-El-Goud, Samah Wagdy Elkhayat, Ahmed Fathy Hamed, Seham Ahmed Abokresha

Journal of Medicine in Scientific Research

Background and objectives: Diabetes mellitus (DM) is a metabolic disease characterized by insufficient insulin synthesis, action, or both. Its prevalence is estimated to be alarmingly increasing. The aim of the study was studying factors influencing the non-compliance of diabetic students at Sohag University with treatment. Methods: Cross-sectional study at Sohag University for 7 months. Total number of diabetic students involved in the study was 153 students chosen from medical reports of administration of medical affairs in the university from May to November 2022; the participants who were studying in a scientific faculty were 51 (33.3%), and in Literary faculty were …

Assessment Of The Eligibility Of Triglyceride;Glucose Index And Triglyceride;High-Density Lipoprotein Cholesterol Ratio As Applicable Insulin Resistance Indices Among Overweight/Obese Egyptians, Ghada A. Omar, Mona A.E A. Hussein, Wafaa S. Hegab

Journal of Medicine in Scientific Research

Background Insulin resistance (IR) means the requirement of a higher insulin concentration to produce the expected biological effect. It was proposed that triglycerides–glucose index (TY G) and triglycerides–high-density lipoprotein cholesterol ratio (TG/HDL) were dependable, applicable, and less-expensive markers of IR. However, their results varied significantly among different ethnic groups. Aim To assess the eligibility of TY G and TG/HDL as IR indices among overweight and/or obese Egyptians. Patients and methods The participants in this cross-sectional study were 328 overweight and/or obese Egyptians. Their fasting blood glucose, TG, HDL, and fasting insulin blood concentrations were estimated. Homeostasis model assessment-insulin resistance (HOMA-IR), …

A Comparative Study On The Effects Of Dextrose Prolotherapy And Local Steroid Injection In Patients With Lateral Epicondylitis: A Randomized Controlled Trial, Abhishek Biswas, Ameed Equebal, Osama Neyaz, Rajkumar Yadav, Suvrat Gupta

Journal of Medicine in Scientific Research

Background Lateral epicondylitis (LE) is the most common condition of elbow pain. Multiple intralesional steroid injections help in the treatment. Prolotherapy is a traditional injection method recently categorized as regenerative treatment. However, there is scarcity of literature that compares its effectiveness with steroids. Objective The aim was to compare the effectiveness of dextrose prolotherapy (DP) against local steroid injection in patients with LE in relieving pain and improving dysfunction. Participants and methods This parallel, randomized controlled trial was conducted at Outpatient Department, National Institute for Locomotor Disabilities (Divyangjan), (erstwhile National Institute for the Orthopaedically Handicapped) Kolkata, from January 2016 to …

Effect Of Different Modalities Of Noninvasive Respiratorys Upport In Preterm Infants With Respiratory Distress Syndrome: A Prospective Multicenter Study, Abeer E. S. Hamed, Alaa A. Rashad, Heba Allah M. Sherief, Magued A. Iskandar, Mahmoud H. Dawabah, Manar A. Eldesouky, Mohamed A. Ibrahim, Sohaila A. Abd El-Halim

Journal of Medicine in Scientific Research

Background The first few hours after birth are very critical for newborns to adapt to the extrauterine environment. However, respiratory distress syndrome (RDS) is very common in newborns, particularly in those with shorter gestation ages, sepsis, and fewer platelet counts. The evaluation of respiratory management with current noninvasive ventilation (NIV) support strategies in preterm infants present within the neonatal intensive care unit, as well as drawbacks of NIV modes including nasal continuous positive airway pressure, nasal intermittent positive pressure ventilation, and high-flow nasal cannula, is also critical for those patients. This study aimed to compare different modes of NIV to …

Comparative Study Between Different Types Of Neonatal Sepsis Among Newborns Admitted To The Neonatal Intensive Care Unit In Mataria Teaching Hospital, Cairo, Nada M. Elsayed, Sohaila A. Abd El-Halim, Youssof M. Hassan

Journal of Medicine in Scientific Research

Background Sepsis is the most frequent cause of neonatal deaths globally, varying in incidence between different countries. Sepsis is a burden on families and health care resources. Objectives To identify prevalence, type of organism, and outcome of early-onset sepsis (EOS) and late-onset sepsis (LOS). Patients and methods A cross-sectional study was conducted at the neonatal ICU of Mataria Teaching Hospital from November 2018 to October 2019. Demographic, clinical, and laboratory data of proved septic neonates were collected. Classification of cases according to the onset of sepsis: EOS (group I), in which sepsis is presented clinically before the third day of …

Could Vitamin D3 Be Effective In Prevention Of Risk Of Preeclampsia Among Pregnant Women?, Adel G. Allam, Ibrahim M. El-Maghraby

Journal of Medicine in Scientific Research

Background Preeclampsia, a pregnancy disease marked by high blood pressure and proteinuria, affects 2–8% of all pregnancies. Preeclampsia can be life-threatening for both the mother and the fetus and is still a significant cause of maternal and neonatal morbidity and mortality. The goal of this study was to assess if there was a link between maternal serum vitamin D3 levels and the severity of preeclampsia. Patients and methods A case–control study was conducted on 70 pregnant women at Shebin El Kom Teaching Hospital. All pregnant women were divided into two groups: group A included 30 apparently healthy pregnant women (control …

The Role Of Myocardial Mechanical And Qtc Dispersion In Detecting Significant Coronary Artery Disease, Mohamed R. Badran

Journal of Medicine in Scientific Research

Background Prolonged myocardial contraction and QT interval duration may be found in ischemic viable myocardium, yet it is unclear if noninvasive examination of regional nonhomogeneous myocardial mechanics and QT duration may detect patients with significant coronary artery disease (CAD). Aim To assess the ability of cardiac mechanical and QTc dispersions to identify significant CAD in patients having chest pain with no prior myocardial infarction. Patients and methods We examined 125 patients who had chest pain and evaluated by coronary angiography. They are divided into two groups. CAD group included 75 patients with significant CAD, and control group included 50 patients …

Correlation Between Neutrophil-To-Lymphocyte Ratio After Percutaneous Coronary Intervention And The Size Of Infarction In Patients With Acute Myocardial Infarction, Mohamed R. Badran

Journal of Medicine in Scientific Research

Background Inflammatory processes have a role in the pathogenesis of acute myocardial infarction (AMI), left ventricular remodeling, and repair. Infarct size (IS) is a strong predictor of prognosis following AMI. Several tools are used to predict IS, but most of them are expensive and inaccessible all the time. So, neutrophil-to-lymphocyte ratio (NLR) as a marker of inflammation is an easy and cheap tool to predict IS. Aim To assess if post-percutaneous coronary intervention (PCI) NLR can predict IS in patients with AMI. Patients and methods The study included 11 125 patients with AMI treated with primary PCI. We used cardiovascular …

Early Versus Late Intervention In Patients With High-Risk Non-St;-Elevation Myocardial Infarction, Emmanuel Louka Aziz, Mohamed Abbas Morsy

Journal of Medicine in Scientific Research

Introduction With improvements in percutaneous coronary intervention and the advent of novel adjunctive pharmacotherapy agents (such as GP 2b/3a inhibitors, new antiplatelet agents, and intensive statin regimens), the safety and efficacy of early Percutaneous coronary intervention (PCI) in acute coronary syndrome (ACS) has improved significantly (1). Therefore, the current guidelines recommend a routine invasive strategy (angiography and revascularization if applicable) (2) in high-risk patients with non-'ST'-elevation ACS (NSTE-ACS). Aim The aim was to compare the results of early versus late intervention in patients with high-risk NSTE myocardial infarction (MI). Patients and methods This study was carried out on 60 patients …

The Effect Of Cardiovascular Risk Factors On The Final Outcome In Patients With Covid-19, Emmanuel Louka Aziz, George Ghaly Gerges

Journal of Medicine in Scientific Research

Background Increased cardiovascular risk factors are associated with adverse outcome in patients with coronavirus disease-2019 (COVID-19). In this study, the authors assessed the prevalence of cardiovascular risk factors in patients with COVID-19 and studied the impact of these cardiovascular risk factors on the final outcome in these patients. Aim The authors aimed to study the prevalence of cardiovascular risk factors in patients with COVID-19 as well as the impact of these cardiovascular risk factors on the final outcome in these patients. Patients and methods The study included 200 patients who were admitted in Al-Sahel teaching hospital with COVID- 19-positive PCR. …

A Rare Case Of Dystrophinopathy: Duchenne Muscular Dystrophy;Becker Muscular Dystrophy Intermediate Complex, Manish S. Ahuja, Neena Katoch, Rachna Gulati, Subhendu Pandit, Tathagata Bose

Journal of Medicine in Scientific Research

An 18-year-old boy with no significant perinatal history presented with insidious onset of slowly progressive flaccid paraparesis with muscle wasting in thighs. On examination, the patient had flaccid motor quadriparesis and partial atrophy of proximal thigh muscles. This was accompanied by pseudohypertrophy of calf muscles and extensor muscles in the dorsum of foot. Investigations revealed very high levels of creatinine phosphokinase in the patient (6495 IU/l in contrast to normal range of 55–170 IU/l) and in his sister (718 IU/l). Echocardiography showed dilated cardiomyopathy with severe left ventricular dysfunction. The multiplex ligation-dependent probe amplification revealed deletion of exons 3 to …

Role Of Crp In Covid-19 Pneumonia: A Single-Center Experience Of 1000 Cases In A Tertiary Care Setting In India, Manojkumar Bhadake, Shital Patil, Utreshwar Dhumal

Journal of Medicine in Scientific Research

Introduction Robust data are available for C-reactive protein (CRP) in bacterial infection, and it can be used in this coronavirus disease 2019 (COVID-19) pneumonia pandemic for initial assessment before planning of treatment in indoor settings in comparison with other inflammatory markers and computed tomography (CT) severity. Materials and methods A prospective, observational, follow up study was conducted that included 1000 COVID 19 cases confirmed with RT PCR. All cases were assessed with lung involvement documented and categorized based on high resolution computed tomography (HRCT) thorax, oxygen saturation, and inflammatory markers such as CRP at the entry point and follow up. …

Comparative Study Between Right-Sided Minithoracotomy Versus Upper Partial Ministernotomy In Isolated Mitral Valve Replacement (Early Outcome), Ashraf Abdelaziz, Emmanuel L. Aziz, Hazem G. Bakr

Journal of Medicine in Scientific Research

Background In recent years, minimally invasive surgical techniques have become increasingly popular in heart surgery. The most common incisions used in minimally invasive mitral valve replacement are ministernotomy and minithoracotomy. It is still up for dispute whether one incision is superior to the other. Patients and methods The results of 60 patients who had solitary mitral valve replacement were studied using a prospective comparative analysis. In group A (n = 30), a minimally invasive right anterior minithoracotomy technique was performed, whereas in group B (n = 30), a partial upper ministernotomy procedure was used. Results The results in …

Comparative Study Between Minimally Invasive Right Anterior Minithoracotomy Versus Mini-Upper Sternotomy In Isolated Aortic Valve Replacement (Early Outcome), Ashraf Abdelaziz, Hazem G. Bakr, Ibrahim M. Helmi

Journal of Medicine in Scientific Research

Background Minimally invasive surgical methods have lately become popular in heart surgery. Ministernotomy and minithoracotomy are the most commonly used incisions in minimally invasive aortic valve replacement. It is still debated if one incision is better than the other. Patients and methods A prospective comparative analysis was used to examine the outcomes of 30 patients who underwent isolated aortic valve replacement. A minimally invasive right anterior minithoracotomy approach was used in group A (n = 15), whereas a mini-upper sternotomy method was used in group B (n = 15). Results The results in both groups reveal no statistical …

Erratum: Parents’ Knowledge, Attitude And Practices Toward Oral Health Of Their Children With Primary Dentition: A Cross Sectional Study, Marwa Foad, Mennatallah Helal, Soad Abdel Moneim

Journal of Medicine in Scientific Research

The Erratum statement can be found in the PDF file.

Should Near Systemic Pulmonary Hypertension Be A Contraindication For Rheumatic Mitral Stenosis Valve Surgery In Egyptian Population?, Ahmed Mostafa Omran, Hany Fayed

Journal of Medicine in Scientific Research

Background: pulmonary hypertension is a well known risk factor leading to mortality and morbidity in Mitral stenosis patients, in spite of long term outcome are being comparable regarding severe and mild or moderate pulmonary hypertension but definitely short term results are worse.

Objective: new management protocol to decrease the immediate postoperative differences between patients having Mitral stenosis with near systemic pulmonary hypertension compared to patients with mild or moderate pulmonary hypertension.

Patients and Methods: Prospective cohort single centre study was held in National heart institute, between 2016 and 2022, on patients undergoing Mitral valve surgery for Mitral stenosis with near …