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Articles 511 - 514 of 514
Full-Text Articles in Medical Specialties
Evaluation Of Oxytocin And Serotonin Levels In Autism Spectrum Disorder, Amal El-Ramly, Azza Samy, Eman Soliman, Golnar Oteify
Evaluation Of Oxytocin And Serotonin Levels In Autism Spectrum Disorder, Amal El-Ramly, Azza Samy, Eman Soliman, Golnar Oteify
Journal of Medicine in Scientific Research
Objective Autism spectrum disorder (ASD) is a complex neurological and developmental disorder that affects how a person acts and interacts, communicates with others, and learns. Endocrine and neuropeptide factors are some among the list of possible etiologic or predisposing contenders. Abnormalities in the brain serotonin system are reported in ASD, including evidence of altered serotonin synthesis and receptor binding, as well as dystrophic serotonergic axons. Blood oxytocin levels are also a focus of ASD research. This work aimed to assess oxytocin and serotonin levels as biomarkers in individuals with ASD. Participants and methods Serotonin and oxytocin levels, as biochemical parameters …
Outcome Of Cochlear Implantation In Children With Enlarged Vestibular Aqueduct (Eva) And Mondini Dysplasia (Incomplete Partition Type Ii), Abir Omara, Amr Younes, Azza Sami, Ihab Sefein, Iman Elrouby, Soha Hamada
Outcome Of Cochlear Implantation In Children With Enlarged Vestibular Aqueduct (Eva) And Mondini Dysplasia (Incomplete Partition Type Ii), Abir Omara, Amr Younes, Azza Sami, Ihab Sefein, Iman Elrouby, Soha Hamada
Journal of Medicine in Scientific Research
Background Congenital inner ear abnormality is a major cause of sensorineural hearing loss in children, about 20% of children with congenital sensorineural hearing loss (SNHL) have associated malformations of the temporal bone, and increased experience in cochlear implantation has led to more children with abnormal cochleo-vestibular anatomy submitted to this procedure. Aim To evaluate the outcome of cochlear implantation in cases with enlarged vestibular aqueduct (EVA) and Mondini deformity (incomplete partition type II) following cochlear implantation and comparing the results with cochlear implant cases without inner ear anomalies. Patients and methods 69 children all less than 6 years of age, …
Technical Aspect Of Mechanical Thrombectomy Of Acute Ischemic Stroke, Ahmed El-Bassiouny, Magdy Khalaf, Romany Adly
Technical Aspect Of Mechanical Thrombectomy Of Acute Ischemic Stroke, Ahmed El-Bassiouny, Magdy Khalaf, Romany Adly
Journal of Medicine in Scientific Research
Background and purpose Mechanical thrombectomy was recently reported of having the potential to treat acute ischemic stroke. However, few comparative studies on neurothrombectomy devices are reported. This study aims to compare two retrievable stent systems according to their safety and effectiveness in patients with acute ischemic stroke. Patients and methods In this study, the clinical, radiological, and functional outcomes of 20 patients with acute ischemic stroke are compared prospectively. Patients were treated with either Trevo retriever (TR) or Solitaire stent (ST) according to the neurointerventionalist preference. Successful recanalization was defined as thrombolysis in cerebral ischemia grade 2a to 3. Results …
Association Study Between Polymorphisms Of Dopamine Transporter Gene (Slc6a3), Dopamine D1 Receptor Gene (Drd1), And Autism, Azza Abdel Aziz Azzam, Dina Mohammad Rasheed Bahgat, Ranaih Massoud Azme Nasralla, Rasha Mohamad Hosny Shahin
Association Study Between Polymorphisms Of Dopamine Transporter Gene (Slc6a3), Dopamine D1 Receptor Gene (Drd1), And Autism, Azza Abdel Aziz Azzam, Dina Mohammad Rasheed Bahgat, Ranaih Massoud Azme Nasralla, Rasha Mohamad Hosny Shahin
Journal of Medicine in Scientific Research
Introduction Autism is an etiologically and clinically heterogeneous group of disorders, collectively referred to as 'autism spectrum disorders'. Dopamine (DA) modulates a wide variety of processes, functions, and behaviors that are abnormal in individuals with autism spectrum disorders. The DA transporter gene SLC6A3 (solute carrier family 6, member 3) is a crucial regulator of DA homeostasis and neurotransmission. SLC6A3 gene has many polymorphisms which are associated with hangs in gene expression that may affect extracellular DA levels. The rs2550936 single-nucleotide polymorphism (SNP) at SLC6A3 gene decreased SLC6A3 expression or DA transporter availability. Also, the rs4532 SNP at dopamine D1 receptors …