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Al-Azhar University

Journal

Articles 1201 - 1230 of 1235

Full-Text Articles in Medical Specialties

Impact Of Functional Endoscopic Sinus Surgery For Cases With Nasal Polypi On Pulmonary Function Tests, El-Sayed Siam, Mohammad Al-Morsy, Mahmoud Abouzaid Feb 2020

Impact Of Functional Endoscopic Sinus Surgery For Cases With Nasal Polypi On Pulmonary Function Tests, El-Sayed Siam, Mohammad Al-Morsy, Mahmoud Abouzaid

Al-Azhar International Medical Journal

Background: The upper and lower airways form one contiguous and functionally related organ, and are frequently exposed to similar inflammatory stimuli. There is increasing interest in the possibility that disease processes in one part of the airway may be reflected or manifest in another, thereby providing opportunities for dual diagnosis and therapy. Aim of this work: is to study the effect of removal of nasal polypi by functional endoscopic sinus surgery on pulmonary function tests. Patients and methods: This prospective study was carried out at Al-Azhar University hospitals (Al-Hussein and Bab El-Shaaria) in the period between December 2018 to December …

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Short Term Outcome Of Coronary Artery Bypass Surgery In Patients With Impaired Left Ventricular Systolic Function, Abdallah Mahmoud, Elhusseiny Gamil, Zakaria Al-Mashtoly, Bahaa El Khonizy, Medhat Refaie Feb 2020

Short Term Outcome Of Coronary Artery Bypass Surgery In Patients With Impaired Left Ventricular Systolic Function, Abdallah Mahmoud, Elhusseiny Gamil, Zakaria Al-Mashtoly, Bahaa El Khonizy, Medhat Refaie

Al-Azhar International Medical Journal

Abstract Background: Coronary artery bypass graft surgery (CABG) in patients with left ventricular dysfunction was associated with improved survival compared to medical treatment. We aimed to evaluate the short-term outcome of CABG in patients with an ejection fraction of ≤ 40%. Methods: Forty patients with ejection fraction (EF) ≤40% underwent CABG between December 2015 and August 2019. Patients with moderate to severe mitral regurgitation, concomitant severe liver and kidney impairment, re-operative CABG, who had concomitant procedures with CABG were excluded. The mean age was 56.72±12.44 years; 30 patients (75%) were males. Twenty-six patients (65%) were diabetics, 28 patients (70%) were …

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Evaluation Of The Effect Of Topical Heparin On The Treatment Of Facial Burn, Fawzy Hamza, Ahmed Salim, Hossam Rizk Feb 2020

Evaluation Of The Effect Of Topical Heparin On The Treatment Of Facial Burn, Fawzy Hamza, Ahmed Salim, Hossam Rizk

Al-Azhar International Medical Journal

Background: Burn is a complex disease process; visible disfigurement caused by burns translates into an altered pattern of socialization which can have serious psychological ramifications. Objectives: The aim of this work was to evaluate the efficacy of topical heparin on the treatment of facial burn regarding pain relief, antibiotic requirements and healing time. Patients and Methods: This is a prospective controlled random study. That included 40 patients, 15-60 years of age, males and females having acute thermal burn up to 20% TBSA including the face, They were subjected either to dressing with topical heparin or topical anti-microbial creams. This study …

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Corneal Topographic Changes After Subscleral Trabeculectomy, Mohamed El Ashkar Feb 2020

Corneal Topographic Changes After Subscleral Trabeculectomy, Mohamed El Ashkar

Al-Azhar International Medical Journal

Background: Glaucoma is a cause of permanent blindness and occurs most often in older adults. Although glaucoma can be initially managed by conservative treatments, trabeculectomy, initially described by has traditionally been considered the “gold standard” for filtration surgery. Aim of the study: is to investigate the effect of trabeculectomy on corneal topography, anterior chamber depth, and aberrations by a SIRIUS topography. Patients and methods: The present study was a prospective cohort study including 30 eyes of patients who were scheduled to undergo trabeculectomy at Ophthalmology Department of Al Azhar university hospital during the period from January 2018 to August 2019. …

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Evaluation Of Desarda Technique In Inguinal Herniorrhaphy, Mustafa Khairy, Abd El-Wahab Madbouly, Mohammed Sharaf Feb 2020

Evaluation Of Desarda Technique In Inguinal Herniorrhaphy, Mustafa Khairy, Abd El-Wahab Madbouly, Mohammed Sharaf

Al-Azhar International Medical Journal

Background: Desarda technique for hernia repair is emerging technique for inguinal hernia repair known for its low-cost procedure, less recurrence rate and feasibility of the procedure. Aim of the work: was to evaluate treatment of inguinal hernia with this method in terms of various operative and post-operative parameters. Patients and methods: The present study included 100 male patients, presented to Al-Hussain University Hospital, for elective repair of uncomplicated inguinal hernia, during the period from March 2015 till November 2018. All the 100 patients subjected to Desarda non mesh tissue repair. Results: Mean operating time was 45.25±12.55 min. There were no …

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Surgical Outcome Of Coronary Artery Bypass Graft In Patients With Previous Coronary Stenting, Alaa Mohamed, Elhusseiny Gamil, Medhat Refaie, Ismail El-Sokkary Feb 2020

Surgical Outcome Of Coronary Artery Bypass Graft In Patients With Previous Coronary Stenting, Alaa Mohamed, Elhusseiny Gamil, Medhat Refaie, Ismail El-Sokkary

Al-Azhar International Medical Journal

Background: With the advancement of percutaneous coronary interventions, patients are presenting to coronary artery bypass grafting (CABG) older, with several co-morbidities and with prior coronary stenting. The outcome of surgery after stenting continues to be debated. We evaluated the surgical outcome of coronary artery bypass grafting in patients with previous coronary stenting. Methods: This prospective cohort study included 50 patients with previous coronary stent who underwent CABG between February 2016 and June 2017. Thirty-eight patients were males (76%), and the mean age was 57.66±8.81 years. The mean ejection fraction was 41.43±9.25%. Forty-six patients (92%) had previous one stent, and 4 …

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Endoscopic Transsphenoidal Approach For Extrasellar Extended Pituitary Macroadenomas, Surgical Outcome., Abdelfattah Shehab, Mohammad Eissa, Rabab Abdelkareem, Tawfik Elkholy Feb 2020

Endoscopic Transsphenoidal Approach For Extrasellar Extended Pituitary Macroadenomas, Surgical Outcome., Abdelfattah Shehab, Mohammad Eissa, Rabab Abdelkareem, Tawfik Elkholy

Al-Azhar International Medical Journal

Abstract Words: 246 Background: Transsphenoidal approaches usually are the preferred method for treatment of pituitary tumors because of a lower risk of complications. Recently, endoscope has been Abstract Words: 246 Background: Transsphenoidal approaches usually are the preferred method for treatment of pituitary tumors because of a lower risk of complications. Recently, endoscope has been introduced as an alternative and effective tool in transsphenoidal surgery. This study was conducted at Al-Azhar University Hospitals and Nasr City Health Insurance Hospital to evaluate the role of endoscope in dealing with pituitary tumors with suprasellar and parasellar extensions. Patients and methods: A total of …

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Amenorrhea Induced By Chemotherapy In Premenopausal Breast Cancer Patients (Retrospective Study), El Sayed Raafat, Hassan Khaled, Hesham Abbas Jan 2020

Amenorrhea Induced By Chemotherapy In Premenopausal Breast Cancer Patients (Retrospective Study), El Sayed Raafat, Hassan Khaled, Hesham Abbas

Al-Azhar International Medical Journal

Background: Breast cancer is the most frequently diagnosed cancer globally and is the leading cause of cancer-related death in women. The American Cancer Society estimates that 249, 260 Americans will be diagnosed with invasive breast cancer. Objectives: This is a retrospective study aiming to identify the frequency of amenorrhea (ovarian failure) after different chemotherapy regimens in premenopausal patients with breast cancer as well as the associated other risk factors that could influence the rate of amenorrhea. Patients and Methods: This study will include patients with breast cancer with at least a minimum follow up of six months after last cycle …

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Conservative Treatment Of Grade Iii Acromioclavicular Joint Dislocation, Islam Hashim, Emad Zayed Jan 2020

Conservative Treatment Of Grade Iii Acromioclavicular Joint Dislocation, Islam Hashim, Emad Zayed

Al-Azhar International Medical Journal

Abstract Background: The acromio-clavicular (AC) joint stability depends on the acromio-clavicular ligaments, the coraco-clavicular (CC) ligaments,and the joint capsule. Treatment of acute type III injuries still controversial We evaluated the results of conservative treatment of type III AC joint dislocation according to clinical and radiological outcome. Patients and Methods: This prospective study included fifteen patients with acute acromio-clavicular joint dislocations type III. There were one woman and fourteen men, with an average age of 29.7 ±10.2 years. All patients underwent clinical assessment according to Constant score and a radiographic study (antero-posterior showing both shoulders, axillary views).All patients were treated conservatively …

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Effect Of High Volume Hemodiafiltration On Secondary Hyperparathyroidism Among Hemodialysis Patients, Ahmed Alsawy Jan 2020

Effect Of High Volume Hemodiafiltration On Secondary Hyperparathyroidism Among Hemodialysis Patients, Ahmed Alsawy

Al-Azhar International Medical Journal

Abstract Background: Despite increasing knowledge of the uraemic syndrome,both morbidity and mortality remain unacceptably high in patients with chronic kidney disease. Study investigates the differences between conventional hemodialysis and hemodiafiltration in the context of chronic kidney disease metabolic bone disease findings, serum calcium (sCa), phosphate (sPO4) and intact parathyroid hormone (PTHint) concentrations. Patients and methods: This prospective cross over study was approved by Almaadi hospital committee and included 95patients with CKD5 on regular hemodialysis for at least 6months.Patients were divided into two groups:Group A:60patients scheduled 6months conventional high flux(hf-HD)(Period1) followed by 6months of post-dilutional –HDF (Period2). Group B:(controls)included 35patients were …

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Combined Anterior Cruciate Ligament Reconstruction And High Tibial Osteotomy In Anterior Cruciate Ligament-Deficient Varus Knees, Hamed Mohammed Jan 2020

Combined Anterior Cruciate Ligament Reconstruction And High Tibial Osteotomy In Anterior Cruciate Ligament-Deficient Varus Knees, Hamed Mohammed

Al-Azhar International Medical Journal

Background: The presence of varus deformity in anterior cruciate ligament (ACL)-deficient knees can be a source of persistent knee pain owing to medial compartment overload. This deformity may threaten the outcome of ACL reconstruction because of increased tension on the graft. Methods: In the period between May 2018 to september 2019, short term pilot study including 10 patients with ACL deficiency and genu varus were treated by anatomical single bundle ACL reconstruction and open medial wedge high tibial osteotomy in same sitting. The selected patients had manifestations of ACL deficiency in association with medial joint line pain with or without …

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Changes Of Corneal Topographic Measurements And Refractive Errors After Horizontal Muscle Surgery. A Case Series, Nour Elwakeel Jan 2020

Changes Of Corneal Topographic Measurements And Refractive Errors After Horizontal Muscle Surgery. A Case Series, Nour Elwakeel

Al-Azhar International Medical Journal

Abstract Background: Refractive and corneal topographic changes after routine strabismus surgery have been reported and can occur even after a successful surgery. Study aims to evaluate the effect of horizontal muscle surgery on refractive errors and corneal measurements. Patients and methods: This study includes 25 eyes of 22 patients who have manifest strabismus. The patients were divided into two groups. Group A (10 eyes of 7 patients) subjected to unilateral lateral rectus recession. Group B (15 eyes of 15 patients) all of them subjected to lateral rectus recession and medial rectus resection in the same eye. Cycloplegic automated refraction (including …

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Endometrial Flushing Versus Endometrial Brush Cytology In High Risk Women For Endometrial Carcinoma, Abdullah Mokbel Jan 2020

Endometrial Flushing Versus Endometrial Brush Cytology In High Risk Women For Endometrial Carcinoma, Abdullah Mokbel

Al-Azhar International Medical Journal

Background: Postmenopausal bleeding (PMB), defined as blood loss occurring at least 12 months after menopause, is a common complaint in general gynecological practice. The prevalence of PMB is approximately 10% immediately after menopause. Aim of work: This study aims to compare between two diagnostic methods Flush and Brush cytology. Patients and Methods: The study population comprises eighty (80) women with postmenopausal bleeding, was conducted over 12 months from April 2018, to April 2019 on postmenopausal women who were approached, managed and followed up in the Gynecology Clinic of Minia General Hospital to compare between two diagnostic methods Flush and Brush …

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Risk Of Recurrent Laryngeal Nerve Injury In Complete Resection Of Recurrent Multi-Nodular Goiter, Khalid Elkhateeb, Amr Elgohary, Mohamed Sharaf Jan 2020

Risk Of Recurrent Laryngeal Nerve Injury In Complete Resection Of Recurrent Multi-Nodular Goiter, Khalid Elkhateeb, Amr Elgohary, Mohamed Sharaf

Al-Azhar International Medical Journal

Background: Anatomic and functional preservation of the recurrent laryngeal nerve (RLN) is the gold standard in thyroid and various neck surgery. Aim of the work: To assess incidence and risk factors for (RLN) injury which may be just palsy or permanent injury postoperative after thyroid surgery in patient with recurrent multiple nodular goiter (MNG) and observe the timing of recovery. Methods: This prospective cross-sectional study was done on fifty patients with recurrent MNG. The study was done from December 2018 to October 2019. Patients with voice changes, RLN injury from previous operation and other type of cancer thyroid were excluded …

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Echocardigraphic Assessment Of Right Ventricular Outflow Tract Function In Patients With Chronic Heart Failure, Ehab Alhefny, Yasser Abdelgaleel, Mostafa Saleh Jan 2020

Echocardigraphic Assessment Of Right Ventricular Outflow Tract Function In Patients With Chronic Heart Failure, Ehab Alhefny, Yasser Abdelgaleel, Mostafa Saleh

Al-Azhar International Medical Journal

ABSTRACT Background: Heart failure (HF) is a progressive , clinical disease where a subset of HF patients has symptoms unrelated to the hemodynamic status and left ventricular ejection fraction . The Right ventricular (RV) function is considered to be a reliable prognostic element in HF, although assessing it is a challenge because of the complexity of the RV. Objective: This study aimed to investigate the clinical application of RV outflow tract (RVOT) function measured by transthoracic echocardiography in HF patients. Method: The investigation of 80 chronic HF patients with dilated dimensions and left ventricular systolic dysfunction (EF less than 40%) …

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Original Article Template For Al-Azhar International Medical Journal: Academic Witting To A Scientific Journal, Yasser Helmy Jan 2020

Original Article Template For Al-Azhar International Medical Journal: Academic Witting To A Scientific Journal, Yasser Helmy

Al-Azhar International Medical Journal

This Article is an Editor-in-Chief Lecture. It will help you to understand a lot of Knowledge about Academic writing and preparation of a scientific article to Al-Azhar International Medical Journal (AIMJ) or any other Journal worldwide. It describes the requirements of Academic writing in details. It provides so many of tips for perfect structuring of the Article, that would make a scientific work ready for primary acceptance by most of editors, if really followed up.

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Treatment Outcome In Patients With Metastatic Non-Small Cell Lung Cancer At Presentation (Retrospective Study), Abd Elmonaem Abd Elmonaem Jan 2020

Treatment Outcome In Patients With Metastatic Non-Small Cell Lung Cancer At Presentation (Retrospective Study), Abd Elmonaem Abd Elmonaem

Al-Azhar International Medical Journal

Background: Worldwide, lung cancer representing 13% of all new cancer cases And has the highest mortality rate . In Egypt, lung cancer incidence is about 4.6% of all cancers . recent trials reporting that immune therapy (anti PDL1) showed a significant superior progression-free survival (PFS) and overall survival (OS) if compared with standard chemotherapy Objectives: To assess outcome of treatment in patients with metastatic non-small cell lung cancer at presentation, in term of response to treatment, progression free survival and, overall survival, treatment related toxicity. Patients and Methods: patient related data: Age, sex, special habits, and performance status. Disease related …

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Impact Of Hormonal Treatment In Patients With Metastatic Prostatic Carcinoma (Retrospective Study), Hytham Salama, Mohsen Zikri, Wael El-Sheshtawy Jan 2020

Impact Of Hormonal Treatment In Patients With Metastatic Prostatic Carcinoma (Retrospective Study), Hytham Salama, Mohsen Zikri, Wael El-Sheshtawy

Al-Azhar International Medical Journal

Abstract Background: worldwide, prostate cancer is the second most common cancer and the fifth leading cause of death from cancer in men. Objective: studying the impact of hormonal treatment in patients with metastatic prostatic carcinoma. Subjects and Methods: This retrospective study included all patients diagnosed with metastatic prostate cancer, treated at our center between the year 2007 and 2016, data of patients included was reviewed from the charts and analyzed for outcome. Results: the study included 39 patients, 21 patients (52.6 %) had subjected to primary bilateral orchiectomy as first line management while (18) patients (47.4%) received ADT. Median PFS …

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Reconstruction Of Alar Lining And Nostril Base By Oral Mucosal Flap On Muscular Pedicle, Osama Alshahat, Yasser Helmy Ali, Ayman Farahat, Ibrhim Eldosoky Jan 2020

Reconstruction Of Alar Lining And Nostril Base By Oral Mucosal Flap On Muscular Pedicle, Osama Alshahat, Yasser Helmy Ali, Ayman Farahat, Ibrhim Eldosoky

Al-Azhar International Medical Journal

Background: Nostril base and Alar wings are forming the major part of the nasal vestibule. This study proposes an innovative technique for functional restoration of alar lining and nostril base by myomucosal oral flap. It also evaluates the functional and aesthetic results of this technique after reconstruction of the nostril and alar subunits. Patients and Methods: Case series study for the proposed technique. Study duration is one year, from start of 2018 till start of 2019. Each patient followed for 6 months. Study setting is a university-based plastic surgery practice. 12 Patients were complaining of unilateral nasal opening distortion due …

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Comparative Study Between Antegrade Intramedullary K-Wires Fixation Versus Transfixing K-Wires Of The 5th Metacarpal Neck Fractures, Mohamed Abd El Shafy, Ehab Elzahed, Adnan Sebaie Jan 2020

Comparative Study Between Antegrade Intramedullary K-Wires Fixation Versus Transfixing K-Wires Of The 5th Metacarpal Neck Fractures, Mohamed Abd El Shafy, Ehab Elzahed, Adnan Sebaie

Al-Azhar International Medical Journal

The neck of the 5th metacarpal fractures ‘‘Boxer Fractures’’ are so common fractures of the hand . Mostly, the dominant hand is affected as common mode of trauma is punching .The appropriate treatment for a Boxer’s fracture varies based on whether the fracture is open or closed, the degree of angulation and rotation .The majority of closed Boxer’s fractures treated conservatively. But surgery is preferred for those have palmar angulation exceeds 30o , malrotation , Irreducible or shortening >3 mm. This study aims to compare clinical and radiological results and the complication rates after reduction and fixation of closed Boxer …

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Factors Affecting Heart And Anterior Descending Coronary Artery Radiation Dose During Left Breast Irradiation (Dosimetric Retrospective Study), Wael Mohamed Jan 2020

Factors Affecting Heart And Anterior Descending Coronary Artery Radiation Dose During Left Breast Irradiation (Dosimetric Retrospective Study), Wael Mohamed

Al-Azhar International Medical Journal

Background: Breast cancer is the commonest cancer in females. Radiotherapy is one of the important factors in treatment of breast cancer. Heart and coronary artery are radio-biologically serial organs. Radiation toxicity in the treatment of breast cancer showed significant clinical problem and increased cardiac morbidity and mortality. Aim of the Work: Assessing Factors affecting heart and anterior descending coronary artery dose during left breast irradiation in 3D technique. Patients and Methods: This study included 69 patients with left breast cancer received radiotherapy to the chest wall or breast tissue at Clinical Oncology Department, Al-Hussein University hospital. Results: heart size and …

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The Effect Of Epidural Magnesium Sulfate As An Adjuvant To Fentanyl For Postoperative Analgesia After Lower Limb Orthopedic Surgery, Sameh Seyam, Khaled Elsheshtawy, Mohamed Morsy Jan 2020

The Effect Of Epidural Magnesium Sulfate As An Adjuvant To Fentanyl For Postoperative Analgesia After Lower Limb Orthopedic Surgery, Sameh Seyam, Khaled Elsheshtawy, Mohamed Morsy

Al-Azhar International Medical Journal

Background Magnesium, a physiological antagonist of calcium and N-methyl-D-aspartate receptors (NMDA), has a role in the prevention of pain in patients undergoing surgeries. Patients and Methods A prospective randomized double-blinded controlled study was conducted on 60 patients undergoing lower extremities arthroscopic surgery. Spinal anesthesia was given an epidural catheter inserted prior to surgery for postoperative pain management. Postoperatively, patients were randomly allocated into three equal groups. Group I (S group; n 20 patients) patients received epidural saline at a rate of 1ml/h for 24 hours. Group II (MI; n 20 patients) patients received 50mg magnesium sulfate followed by continuous epidural …

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Fixed Versus Adjustable Loop Cortical Suspension Devices In Arthroscopic Anterior Cruciate Ligament Reconstruction, Ramy Mohamed, Mohamed El-Shafie, Mohamed El-Sheikh Jan 2020

Fixed Versus Adjustable Loop Cortical Suspension Devices In Arthroscopic Anterior Cruciate Ligament Reconstruction, Ramy Mohamed, Mohamed El-Shafie, Mohamed El-Sheikh

Al-Azhar International Medical Journal

Background: Anterior cruciate ligament reconstruction has remained the gold (ACL) standard for ACL injuries, especially for young individuals and athletes expose to high level sporting activities aiming to return his or her preinjury level of activity. Cortical suspensory femoral fixation is commonly performed for graft fixation to the femur in anterior cruciate ligament (ACL) reconstruction using hamstring tendons. Aim of the work: The aim of the work was to compare the clinical results between fixed and adjustable loop cortical suspension devices in arthroscopic ACL reconstruction using the Lysholm Knee Scoring Scale after 12 months postoperatively. Methods: This study included a …

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Role Of Serum Glypican 3 As A Predictive Tool For Early Diagnosis Of Hepatocellular Carcinoma (Hcc), Mahmoud Mohamed Jan 2020

Role Of Serum Glypican 3 As A Predictive Tool For Early Diagnosis Of Hepatocellular Carcinoma (Hcc), Mahmoud Mohamed

Al-Azhar International Medical Journal

Abstract Background: Hepatocellular carcinoma (HCC) is one of the most aggressive malignancies worldwide and one of the main causes of cancer-related mortality globally. Serum alpha-fetoprotein (AFP) has insufficient sensitivity and specificity for detection of hepatocellular carcinoma (HCC). Estimation of serum level of certain up regulated proteins as glypican-3 (GPC-3) in HCC could be a promising biomarker for screening and early HCC detection. Recently glypican-3 (GPC-3) was suggested as novel biomarkers for the detection HCC. Objective: To determine the role of serum GPC-3 in the early diagnosis of HCC Methods: The study included eighty subjects: 30 patients with HCC and elevated …

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In Vitro Model For Cryptosporidium Parvum Infection, Ahmed Bayoumy, Tarek Zaalouk, Ahmed Agamawy Jan 2020

In Vitro Model For Cryptosporidium Parvum Infection, Ahmed Bayoumy, Tarek Zaalouk, Ahmed Agamawy

Al-Azhar International Medical Journal

ABSTRACT Background: The in vitro culture system of C. parvum has been investigated using numerous cell lines that support the growth of different stages of the parasite which is less expensive and more convenient for the study of host-parasite interactions than in vivo models. Objective of the study: to evaluate in vitro models of C. parvum and to establish an in vitro culture system for further research studies. Material and Methods: Confluent HT-29 Human Colorectal Adenocarcinoma cell monolayers were infected with 4x105 viable C. parvum oocysts, suspended in 200 l cell culture medium (DMEM). Cells were then incubated for 2 …

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Evaluation Of Coloanal Anastomosis After Resection Low Rectal Cancer, Ahmed Mohammed, Ayman Abdul-Mohaymen, Magdy Hussain Jan 2020

Evaluation Of Coloanal Anastomosis After Resection Low Rectal Cancer, Ahmed Mohammed, Ayman Abdul-Mohaymen, Magdy Hussain

Al-Azhar International Medical Journal

Background: The primary goal for the surgical treatment of rectal cancer is to achieve an oncologic cure while preserving function. Intersphincteric resection and colo anal anastomosis is used to treated low rectal cancer and improve quality of life Aim of the work: This study aimed to evaluate the oncological safety of colo anal anastomosis after resection of low rectal cancer with detection of early post-operative complication. Patient and methods: This study included a total 10 patients who underwent total mesorectal excision and colo anal anastomosis attending at Damanhour Oncology Centerfrom decamber 2018 to novamber 2019. Results: Ten patients were included …

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Study The Potential Nephro-Protective Effect Of Stem Cells Compared To Perindopril On Experimentally Induced Nephropathy, Ahmad Abd Ella, Hassan El-Kotby, Abd El-Lateef Abd El-Lateef, Wagih Abd Elhai Jan 2020

Study The Potential Nephro-Protective Effect Of Stem Cells Compared To Perindopril On Experimentally Induced Nephropathy, Ahmad Abd Ella, Hassan El-Kotby, Abd El-Lateef Abd El-Lateef, Wagih Abd Elhai

Al-Azhar International Medical Journal

AKI is as a public health problem worldwide.Gentamicin is one of the leading causes of drug-induced nephrotoxicity.Objective:To assess the reno protective effect of ACEI Perindopril and BMDMCs on gentamicin induced nephrotoxicity in rats.The animals were divided into four groups:group A (Control),GroupB(Gentamicin-treated):It consists of 40 rats received sub-cutaneausly Gentamicin in a dose of 80mg/kg once daily for 7 consecutive days and subdivided into 4 subgroups:B-I:10 rats as acontrol group.B-II:consists of 10 rats on the eighth day after Gentamicin injection they received oral Perindopril at doses of 6 mg/kg per day for4weeks.B-III:consists of10rats on the eighth day after Gentamicin injection, stem cells …

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Evaluation Of The Role Of Fecal Microbiota Transplantation In The Management Of Ulcerative Colitis In Egyptian Patients, Ahmed Ahmed, Gamal Soliman, Mohei Eldin Amer Jan 2020

Evaluation Of The Role Of Fecal Microbiota Transplantation In The Management Of Ulcerative Colitis In Egyptian Patients, Ahmed Ahmed, Gamal Soliman, Mohei Eldin Amer

Al-Azhar International Medical Journal

Background and Aims: Fecal Microbiota Transplantation (FMT) is a novel form of therapeutic microbial manipulation aims to restore the intestinal microbiota in diseased individuals by transferring intestinal microbiota of healthy donors. We aimed to establish the efficacy of, multi donor, fecal microbiota transplantation in active ulcerative colitis(UC) in Egyptian patients. Subjects and Methods: known UC patients (n-50) were divided in two groups, Group one included 25 patients who treated with medical treatment alone and then follow up was done for 24 weeks. Group two included 25 patients who treated with medical treatment and underwent FMT via complete colonoscopy every three …

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Age Related Changes In The Expression Of Tenascin-C In Liver Of Albino Rat, Mohammed Mohammed, Mohammed Mokhtar El Assaly, Hamdino Attia Jan 2020

Age Related Changes In The Expression Of Tenascin-C In Liver Of Albino Rat, Mohammed Mohammed, Mohammed Mokhtar El Assaly, Hamdino Attia

Al-Azhar International Medical Journal

Abstract Background: Aging is a gradual deterioration in the function of tissues and organ systems with loss of the ability to maintain homeostasis, due to structural alteration or dysfunction. Aging impact directly on all the different types of liver cells: hepatocytes, liver sinusoidal endothelial cells (LSECs), Küpffer cells (KCs) and hepatic stellate cells (HSCs). Activation of HSCs leads to deposition of collagen in the space of Disse, decrease of fenestrations of LSECs and formation of basement membrane. These changes called pseudocapillarization. Tenascin-C (TN-C) is an extracellular matrix glycoprotein markedly up-regulated during liver fibrosis. Tenascin-C is highly expressed during embryonic development, …

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The Efficacy Of Bilateral Sphenopalatine Ganglion Block Under General Anesthesia In Trans-Sphenoidal Endoscopic Hypophysectomy, Sawsan Mohamed, Tawfik Elkholy, Mohammad Eissa, Horia Farran Jan 2020

The Efficacy Of Bilateral Sphenopalatine Ganglion Block Under General Anesthesia In Trans-Sphenoidal Endoscopic Hypophysectomy, Sawsan Mohamed, Tawfik Elkholy, Mohammad Eissa, Horia Farran

Al-Azhar International Medical Journal

Background:The most important goal in endoscopic pituitary surgery is bloodless field with better visualization under hemodynamic stability and good analgesia to improve the outcome, the current study was performed to evaluate the intraoperative anesthetic and postoperative analgesic effects of bilateral sphenopalatine ganglion block(SPGB)as adjuvant to general anesthesia in endoscopic transsphenoidal resection of pituitary adenoma. Patients and methods:thirty patients(ASA I-II)aged 22–55 years, randomly assigned into two equal groups. After stabilization of general anesthesia, the patients received bilateral sphenopalatine ganglion block with 2ml of either2% lidocaine: 1:200000 epinephrine(SPGB group)or sterile normal saline(control group). Mean arterial blood pressure was maintained at 60–70mmHg by …

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