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2004

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Articles 151 - 180 of 214

Full-Text Articles in Medical Sciences

Serological Evaluation Of Hsv-1 And Hsv-2 Infection In Pregnancy, Ni̇zami̇ Duran Jan 2004

Serological Evaluation Of Hsv-1 And Hsv-2 Infection In Pregnancy, Ni̇zami̇ Duran

Turkish Journal of Medical Sciences

We performed a serological evaluation of herpes simplex virus (HSV) infections at the time of labor. In order to determine the seroprevalence of asymptomatic HSV infections in pregnant women, blood samples were collected for antibody measurement from 130 randomly selected pregnant women. Presence of HSV IgG and IgM antibodies in the serum samples was tested by ELISA. The prevalence of HSV-1 gG1 antibodies was 90% (117/130), that of HSV-2 gG2 antibodies was 63.1% (82/130) and that of HSV-2 IgM antibodies was 13.8% (18/130). Eight (44.4%) of the pregnant women with HSV-2 IgM were at the same time found to have …

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Insulin Sensitivity, B Cell Function And Serum Lipid Levels In Helicobacter Pylori Positive, Non-Obese, Young Adult Males, Mehmet Dursun, Mi̇that Bahceci̇, Alpaslan Tuzcu, Şeri̇f Yilmaz, Fi̇kri̇ Canoruç Jan 2004

Insulin Sensitivity, B Cell Function And Serum Lipid Levels In Helicobacter Pylori Positive, Non-Obese, Young Adult Males, Mehmet Dursun, Mi̇that Bahceci̇, Alpaslan Tuzcu, Şeri̇f Yilmaz, Fi̇kri̇ Canoruç

Turkish Journal of Medical Sciences

It is not clear whether Helicobacter pylori (Hp) infection affects insulin levels and insulin sensitivity. We aimed to determine insulin sensitivity and beta cell function, and to evaluate serum lipids in subjects with and without Hp infection. Eighty non-obese young adult males, 40 of whom were Hp positive and 40 were negative, were included in the study. Two endoscopic biopsy specimens were obtained from each subject. Height, weight and waist-hip circumference were measured, and body mass index (BMI) was calculated. Serum glucose, total, HDL, LDL and VLDL-cholesterol and triglyceride levels were determined. Body fat mass and percentage were determined by …

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The Intellectual And Scientific Basis Of Parathyroid Surgery, Seza A. Güleç, Ömer Uğur Jan 2004

The Intellectual And Scientific Basis Of Parathyroid Surgery, Seza A. Güleç, Ömer Uğur

Turkish Journal of Medical Sciences

No abstract provided.

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Anterior And Inferior St-Segment Elevation, Left Anterior Descending Artery, Ramazan Akdemi̇r, Hüseyi̇n Gündüz, Hakan Özhan, Mehmet Yazici, Enver Erbi̇len, Ci̇hangi̇r Uyan Jan 2004

Anterior And Inferior St-Segment Elevation, Left Anterior Descending Artery, Ramazan Akdemi̇r, Hüseyi̇n Gündüz, Hakan Özhan, Mehmet Yazici, Enver Erbi̇len, Ci̇hangi̇r Uyan

Turkish Journal of Medical Sciences

AKDEMİR^1, Hüseyin GÜNDÜZ^2, Hakan ÖZHAN^1, Mehmet YAZICI^1, Enver ERBİLEN^1, Cihangir UYAN^2 ^1Department of Cardiology, Düzce Faculty of Medicine, Abant Izzet Baysal University, Düzce - Turkey ^2Department of Cardiology, Izzet Baysal Faculty of Medicine, Abant Izzet Baysal University, Bolu - Turkey

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Point Of Entry To The Health Care System A Community Based Study In Edirne, Turkey*, Erkan Meli̇h Şahi̇n, Özlem Öztürk Şahi̇n Jan 2004

Point Of Entry To The Health Care System A Community Based Study In Edirne, Turkey*, Erkan Meli̇h Şahi̇n, Özlem Öztürk Şahi̇n

Turkish Journal of Medical Sciences

Being the first contact point in the health system is one of the main features of primary health care. Our aim is to identify whether the primary care institutions in Edirne are used as a first contact point for health services. A survey prepared for this study was carried out by face-to-face interviews with 407 families, a representative sample of the Edirne municipality region. The 1,008 adults and adolescents in these families were asked to answer the questions "to which health care institutions do you apply first when you seek health care?" and "to which health care institution do you …

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Investigation Of The Bactericidal Effects Of Vancomycin And Quinupristin/Dalfopristin On Staphylococcus Aureus Isolates, Mi̇ne Hoşgör Li̇moncu, Şafak Ermertcan, Güner Coşar Jan 2004

Investigation Of The Bactericidal Effects Of Vancomycin And Quinupristin/Dalfopristin On Staphylococcus Aureus Isolates, Mi̇ne Hoşgör Li̇moncu, Şafak Ermertcan, Güner Coşar

Turkish Journal of Medical Sciences

The present study aimed to determine the correlation between the bactericidal activity of vancomycin and quinupristin/dalfopristin (Q/D) on Staphylococcus aureus isolates and their minimal inhibition concentrations. The in-vitro susceptibilities of the 99 S. aureus isolates to vancomycin and Q/D were investigated by agar dilution. Thirty methicillin-resistant S. aureus (MRSA) and 30 methicillin-susceptible S. aureus (MSSA) vancomycin and Q/D susceptible isolates were involved in time-kill studies. While both MRSA and MSSA isolates were susceptible to vancomycin, 96% of both isolates were determined as susceptible to Q/D. In the time-kill test, after 6 h of incubation vancomycin exhibited a bactericidal activity of …

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Thyroid Hemiagenesis In A Patient With Hypothyroidism*, Murat Acar, Ayli̇n Yücel, Bumi̇n Deği̇rmenci̇, Ramazan Albayrak Jan 2004

Thyroid Hemiagenesis In A Patient With Hypothyroidism*, Murat Acar, Ayli̇n Yücel, Bumi̇n Deği̇rmenci̇, Ramazan Albayrak

Turkish Journal of Medical Sciences

AR, Aylin YÜCEL, Bumin DEĞİRMENCİ, Ramazan ALBAYRAK Department of Radiology, Faculty of Medicine, Afyon Kocatepe University, Afyon - TURKEY

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Association Of Invasive Breast Carcinoma And Glioblastoma Multiforme: A Case Report With Histological And Immunohistochemical Features, M. Şerefetti̇n Canda, Meri̇h Güray, R. Serhat Erbayraktar, Feri̇dun Acar, Tülay Canda Jan 2004

Association Of Invasive Breast Carcinoma And Glioblastoma Multiforme: A Case Report With Histological And Immunohistochemical Features, M. Şerefetti̇n Canda, Meri̇h Güray, R. Serhat Erbayraktar, Feri̇dun Acar, Tülay Canda

Turkish Journal of Medical Sciences

ettin CANDA^1, Merih GÜRAY^1, R. Serhat ERBAYRAKTAR^2, Feridun ACAR^2, Tülay CANDA ^1Department of Pathology, Faculty of Medicine, Dokuz Eylül University, İnciraltı, İzmir - TURKEY ^2Department of Neurosurgery, Faculty of Medicine Dokuz Eylül University, İnciraltı, İzmir - TURKEY

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Reconstruction Of Localized Defects Of The Anterior Maxillary Ridge With Autogenous Bone Graft Before Insertion Of A Single Implant, Yilmaz Günaydin, Yavuz Si̇nan Aydintuğ, Keri̇m Ortakoğlu, Meti̇n Şençi̇men, Mehmet Dalkiz Jan 2004

Reconstruction Of Localized Defects Of The Anterior Maxillary Ridge With Autogenous Bone Graft Before Insertion Of A Single Implant, Yilmaz Günaydin, Yavuz Si̇nan Aydintuğ, Keri̇m Ortakoğlu, Meti̇n Şençi̇men, Mehmet Dalkiz

Turkish Journal of Medical Sciences

ÜNAYDIN^1, Yavuz Sinan AYDINTUĞ^1, Kerim ORTAKOĞLU^1, Metin ŞENÇİMEN^1, Mehmet DALKIZ^2 ^1Department of Oral and Maxillofacial Surgery, Gülhane Military Medical Academy, Ankara - Turkey ^2Department of Prosthetic Dentistry, Gülhane Military Medical Academy, Ankara - Turkey

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Reversible Posterior Leukoencephalopathy Syndrome Secondary To Acute Hepatic Failure, Hamza Karabi̇ber, Onur Kutlu, Alpay Alkan, İsa Üzüm, Cengi̇z Yakinci Jan 2004

Reversible Posterior Leukoencephalopathy Syndrome Secondary To Acute Hepatic Failure, Hamza Karabi̇ber, Onur Kutlu, Alpay Alkan, İsa Üzüm, Cengi̇z Yakinci

Turkish Journal of Medical Sciences

RABİBER^1, Onur KUTLU^2, Alpay ALKAN^3, İsa ÜZÜM^2, Cengiz YAKINCI^2 ^1Department of Pediatrics, Faculty of Medicine, Kahramanmaraş Sütçü İmam University, Kahramanmaraş - TURKEY ^2Department of Pediatrics, Faculty of Medicine, İnönü University, Malatya - TURKEY ^3Department of Radiology, Faculty of Medicine, İnönü University, Malatya - TURKEY

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Effect Of Vitamin E On Kidney Preservation Using Isolated Perfused Dog Kidney, Adnan Şahi̇n, Cem Algin, Çağatay Sezgi̇n, Enver İhti̇yar Jan 2004

Effect Of Vitamin E On Kidney Preservation Using Isolated Perfused Dog Kidney, Adnan Şahi̇n, Cem Algin, Çağatay Sezgi̇n, Enver İhti̇yar

Turkish Journal of Medical Sciences

Unsuccessful cadaveric kidney transplantation still remains as an important problem in organ transplantation. Cold storage solutions are not very efficient for kidney preservation. Vitamin E is an important dietary antioxidant, which may play a vital role in preventing free radical perfusion injury. We investigated the effect of vitamin E on kidney preservation with Euro-Collins (EC) solution using the isolated perfused dog kidney model. Recipients were randomly divided into 3 groups: group 1 (n = 6), immediately reperfused with EC solution, given laboratory pelleted diet and drinking water for 4 weeks; and group 2 (n = 6), flushed, and stored with …

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Femoral Sulcus Angle Measurements: An Anatomical Study Of Magnetic Resonance Images And Dry Bones, Khalil Awadh Murshed, Aynur Emi̇ne Çi̇çekci̇başi, Taner Zi̇ylan, Aydin Karabacakoğlu Jan 2004

Femoral Sulcus Angle Measurements: An Anatomical Study Of Magnetic Resonance Images And Dry Bones, Khalil Awadh Murshed, Aynur Emi̇ne Çi̇çekci̇başi, Taner Zi̇ylan, Aydin Karabacakoğlu

Turkish Journal of Medical Sciences

The sulcus angle of the femoral trochlea is particularly important for evaluating the patellofemoral joint. Our experimental study aimed to assess the osseous femoral sulcus angle radiologically in the right and left knees and osteologically in the right and left femurs in males and females. The osseous sulcus angle of 28 male right, 22 male left, 21 female right and 29 female left knees was measured on magnetic resonance images (MRIs) and by a goniometer; the angle was measured in 40 right and 40 left femurs. In MRIs, the mean sulcus angle in males and in females was 134° ± …

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Soft Tissue Profile Changes In Anatolian Turkish Girls And Boys Following Orthodontic Treatment With And Without Extractions, Serpi̇l Hazar, Sercan Akyalçin, Hayal Boyacioğlu Jan 2004

Soft Tissue Profile Changes In Anatolian Turkish Girls And Boys Following Orthodontic Treatment With And Without Extractions, Serpi̇l Hazar, Sercan Akyalçin, Hayal Boyacioğlu

Turkish Journal of Medical Sciences

The choice of extraction is critical in treatment planning, and its impact on the final facial appearance can be quite dramatic. Evaluation of facial profile esthetics both before and after treatment should be made cautiously. An orthodontist should be conscious of changes brought about by treatment and by late adolescent growth as well as differences in the dentofacial structures of various ethnic groups. The purpose of this cephalometric investigation was to determine the changes in the soft tissue profile of Turkish children treated with and without extractions. An assessment of pre- and post-treatment faces, chosen from our clinical records by …

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Use Of Spongious Bone Chips And Fascia Temporalis In Alveolar Bone Defects, Hakan H. Tüz, Ümi̇t K. Akal, Mi̇ne Cambazoğlu, Reha Ş. Ki̇şni̇şçi̇ Jan 2004

Use Of Spongious Bone Chips And Fascia Temporalis In Alveolar Bone Defects, Hakan H. Tüz, Ümi̇t K. Akal, Mi̇ne Cambazoğlu, Reha Ş. Ki̇şni̇şçi̇

Turkish Journal of Medical Sciences

Graft materials are used for inducement of regeneration in bone defects. Organic and synthetic bone graft materials facilitate remodelation or healing of the bone and induce new bone formation in the area of bone resorption caused by pathological, traumatic, and physiological reasons. The aim of this study was to evaluate the effects of spongious allogenic bone graft and fascia temporalis membranous collagen tissue on the healing of bone defects clinically and radiologically. The study was carried out on 90 bone defects of 81 patients who underwent apicoectomy, cystectomy, and curettage of chronic infections in the maxilla and mandible. Defects were …

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Identical Twins Presenting With Hydrocephalus, Ahmet Çolak, Murat Kutlay, Burak O. Boran, Nusret Demi̇rcan Jan 2004

Identical Twins Presenting With Hydrocephalus, Ahmet Çolak, Murat Kutlay, Burak O. Boran, Nusret Demi̇rcan

Turkish Journal of Medical Sciences

LAK, Murat KUTLAY, Burak O. BORAN, Nusret DEMİRCAN Department of Neurosurgery, GATA Haydarpaşa Training Hospital, İstanbul - TURKEY

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Liesegang Rings In Breast Tissue: An Unusual Component Of A Foreign Body Reaction, Banu Si̇s, Tülay Canda, Ömer Harmancioğlu Jan 2004

Liesegang Rings In Breast Tissue: An Unusual Component Of A Foreign Body Reaction, Banu Si̇s, Tülay Canda, Ömer Harmancioğlu

Turkish Journal of Medical Sciences

^1, Tülay CANDA^1, Ömer HARMANCIOĞLU^2 ^1Department of Pathology, Faculty of Medicine, Dokuz Eylül University, İzmir - Turkey ^2Department of General Surgery, Faculty of Medicine, Dokuz Eylül University, İzmir - Turkey

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Adenoid Cystic Carcinoma Of The External Auditory Canal With Pulmonary Metastasis, Bumi̇n Deği̇rmenci̇, Ayli̇n Yücel, Murat Acar, Ramazan Albayrak Jan 2004

Adenoid Cystic Carcinoma Of The External Auditory Canal With Pulmonary Metastasis, Bumi̇n Deği̇rmenci̇, Ayli̇n Yücel, Murat Acar, Ramazan Albayrak

Turkish Journal of Medical Sciences

ĞİRMENCİ, Aylin YÜCEL, Murat ACAR, Ramazan ALBAYRAK Department of Radiology, Faculty of Medicine, Kocatepe University, Afyon - TURKEY

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A Family With Chronic Progressive External Ophthalmoplegia, Ayşe Fi̇li̇z Koç, Suzan Zorludemi̇r, Hacer Bozdemi̇r Jan 2004

A Family With Chronic Progressive External Ophthalmoplegia, Ayşe Fi̇li̇z Koç, Suzan Zorludemi̇r, Hacer Bozdemi̇r

Turkish Journal of Medical Sciences

KOÇ^1, Suzan ZORLUDEMİR^2, Hacer BOZDEMİR^1 ^1Department of Neurology, Faculty of Medicine, Çukurova University, Adana - Turkey ^2Department of Pathology, Faculty of Medicine, Çukurova University, Adana - Turkey

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Spinocerebellar Ataxia With A Novel Chromosomal Defect: Del 5q34 - A Case Report, Ayşe Fi̇li̇z Koç, Yakup Sarica, Di̇lara Süleymanova Karahan Jan 2004

Spinocerebellar Ataxia With A Novel Chromosomal Defect: Del 5q34 - A Case Report, Ayşe Fi̇li̇z Koç, Yakup Sarica, Di̇lara Süleymanova Karahan

Turkish Journal of Medical Sciences

KOÇ^1, Yakup SARICA^1, Dilara SÜLEYMANOVA KARAHAN^2 ^1Department of Neurology, Faculty of Medicine, Çukurova University, Adana - Turkey ^2Department of Molecular Biology, Faculty of Medicine, Çukurova University, Adana - Turkey

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Recovery Of 1-Chloro-2,4-Dinitrobenzene Detoxification By N-Acetyl- L-Cysteine In Glutathione Predepleted Human Erythrocytes, Deni̇z Yildiz, C.Işil Kuran Jan 2004

Recovery Of 1-Chloro-2,4-Dinitrobenzene Detoxification By N-Acetyl- L-Cysteine In Glutathione Predepleted Human Erythrocytes, Deni̇z Yildiz, C.Işil Kuran

Turkish Journal of Medical Sciences

Glutathione is an important thiol-containing compound involved in the detoxification process in erythrocytes. Its thiol group reacts with a variety of xenobiotics in a glutathione S-transferase catalyzed reaction to form conjugates that are effluxed from the erythrocytes by an ATP dependent transport mechanism. A well studied experimental system is the transport of the conjugate of glutathione and 1-chloro-2,4-dinitrobenzene. We investigated whether N-acetyl-L-cysteine protects the free-SH content and restores 1-chloro-2,4-dinitrobenzene detoxification in erythrocytes or replaces glutathione in detoxification process in glutathione predepleted erythrocytes. Our results indicate that N-acetyl-L-cysteine restores the intracellular free-SH content following depletion by 1-chloro-2,4-dinitrobenzene and N-ethylmaleimide. N-acetyl-L-cysteine (10 …

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Comparative Cytotoxicity Of Fludarabine In Human Peripheral Blood Mononuclear Cells And In The Promyelocytic Leukemia Cell Line (Hl60), A. Lale Doğan Jan 2004

Comparative Cytotoxicity Of Fludarabine In Human Peripheral Blood Mononuclear Cells And In The Promyelocytic Leukemia Cell Line (Hl60), A. Lale Doğan

Turkish Journal of Medical Sciences

Fludarabine is an inhibitor of DNA/RNA synthesis with antitumor activity on lymphoproliferative malignancies. We investigated the dose-dependent cytotoxic effects of the drug on human peripheral blood mononuclear cells, the HL60 cell line and the differentiated HL60 cells. Dimethylformamide was used for the neutrophilic differentiation of HL60 cells and the MTT assay was used to estimate drug cytotoxicity. Undifferentiated tumor cells had higher proliferation rates compared to the differentiated subline. There was 57% cell death in HL60 cells at a dose of 5 µg/ml of the drug. On the other hand, in differentiated HL60 cells and nonmalignant cells, cell death did …

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Dr. Thomas Willis’ Famous Eponym: The Circle Of Willis, Çağatay Üstün Jan 2004

Dr. Thomas Willis’ Famous Eponym: The Circle Of Willis, Çağatay Üstün

Turkish Journal of Medical Sciences

No abstract provided.

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Brucellosis Seroprevalence In Southeast Turkey (Diyarbakır), Selahatti̇n Atmaca, Tuncer Özeki̇nci̇, Nezahat Akpolat, Saffet Elçi̇, Adnan Suay, Eralp Arikan Jan 2004

Brucellosis Seroprevalence In Southeast Turkey (Diyarbakır), Selahatti̇n Atmaca, Tuncer Özeki̇nci̇, Nezahat Akpolat, Saffet Elçi̇, Adnan Suay, Eralp Arikan

Turkish Journal of Medical Sciences

This study was conducted to determine brucellosis seropositivity in patients suspected of having brucellosis who sought treatment at the Central Laboratory of Dicle University Medical Faculty Hospital in southeast Turkey (Diyarbakır). 20,663 serum samples were collected during the study (1 August 2001-31 December 2002), and 14,480 sera were tested in a 12-month period on a seasonal basis by Rose-Bengal slide agglutination (RBSA), and positive sera were titrated by standard tube agglutination (STA). Titration values of 1/160 and above were considered positive. Of the 20663 sera, 463 (2.2%) tested positive on RBSA. Of these 463 sera, 267 (57.6%) tested positive on …

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Preparation And Evaluation Of Ocular Inserts Containing Norfloxacin, M. Venkateshwar Rao, Somashekar Shyale Jan 2004

Preparation And Evaluation Of Ocular Inserts Containing Norfloxacin, M. Venkateshwar Rao, Somashekar Shyale

Turkish Journal of Medical Sciences

Norfloxacin is a poorly water soluble drug, and to improve its solubility it was complexed with b-cyclodextrin (BCD). Several ocular patches/inserts of norfloxacin-b-cyclodextrin were prepared in hydroxypropyl methyl cellulose (HPMC) matrix. The influence of rate controlling membranes made of ethyl cellulose (EC) alone and in combination with polyvinyl pyrrolidone K30 (PVP K30) in different proportions on drug release kinetics was studied. The data were subjected to regression analysis. Various physical characteristics of the films were evaluated. In vitro release studies were carried out in a fabricated flow through cell. All the films prepared were found to be uniform in thickness, …

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Acute Hepatic Failure In A Case Of Acute Lymphoblastic Leukemia, Sali̇h Cesur, Pervi̇n Topçuoğlu, Ozan Aşik, Serhat Bi̇rengel, Muhi̇t Özcan Jan 2004

Acute Hepatic Failure In A Case Of Acute Lymphoblastic Leukemia, Sali̇h Cesur, Pervi̇n Topçuoğlu, Ozan Aşik, Serhat Bi̇rengel, Muhi̇t Özcan

Turkish Journal of Medical Sciences

SUR^1, Pervin TOPÇUOĞLU^2, Ozan AŞIK^3, Serhat BİRENGEL^3 ,Muhit ÖZCAN^2 ^1Refik Saydam Hygiene Center Tuberculosis Reference Laboratory, Ankara – Turkey ^2 Department of Hematology, Faculty of Medicine, Ankara University, Ankara - Turkey ^3 Department of Infectious Diseases and Clinical Bacteriology, Faculty of Medicine, Ankara University, Ankara - Turkey

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Case Report: Intramesocolic Malposition Of The Gallbladder, Oral Saygun, Kuzey Aydinuraz, Çağatay Daphan, Abdullah Akkus, Fati̇h Ağalar Jan 2004

Case Report: Intramesocolic Malposition Of The Gallbladder, Oral Saygun, Kuzey Aydinuraz, Çağatay Daphan, Abdullah Akkus, Fati̇h Ağalar

Turkish Journal of Medical Sciences

GUN, Kuzey AYDINURAZ, Cağatay DAPHAN, Abdullah AKKUS, Fatih AĞALAR Department of General Surgery, Faculty of Medicine, Kırıkkale University, Kırıkkale - TURKEY

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Can The Natural Carbonic Anhydrase Inhibitors In Trout Plasma Be Used In The Treatment Of Some Human Diseases?, Şükrü Beydemi̇r, Olcay Hi̇sar Jan 2004

Can The Natural Carbonic Anhydrase Inhibitors In Trout Plasma Be Used In The Treatment Of Some Human Diseases?, Şükrü Beydemi̇r, Olcay Hi̇sar

Turkish Journal of Medical Sciences

No abstract provided.

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Typing Of Methicillin-Resistant Staphylococcus Aureus By Ribosome Spacer And Arbitrarily Primed Polymerase Chain Reaction, Tamer Essawi, Kamel Adwan, Nael Abu-Hassan, Galeb Adwan, Ahmed Saleh, Ghaleb Mohammad Adwan Jan 2004

Typing Of Methicillin-Resistant Staphylococcus Aureus By Ribosome Spacer And Arbitrarily Primed Polymerase Chain Reaction, Tamer Essawi, Kamel Adwan, Nael Abu-Hassan, Galeb Adwan, Ahmed Saleh, Ghaleb Mohammad Adwan

Turkish Journal of Medical Sciences

Thirty-five methicillin-resistant Staphylococcus aureus (MRSA) clinical isolates were collected from 3 hospitals in the northern and southern parts of Palestine between February and May 1998. These isolates were typed by ribosome spacer PCR (RS-PCR) and arbitrarily primed PCR (AP-PCR). RS-PCR generated 9 different genotypes. The use of AP-PCR provided a high resolution typing method and allowed us to define 11 different clusters. Three major clusters, however, based on the combination of both typing methods, spread throughout the neonatal and intensive care units of Rafidya Hospital during the entire period.

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Effects Of Weight Loss Induced By Eight-Week Orlistat Therapy On Maximal Work Production Capacity In Obese Females, Oğuz Özçeli̇k, Hali̇l Doğan, Haluk Keleşti̇mur Jan 2004

Effects Of Weight Loss Induced By Eight-Week Orlistat Therapy On Maximal Work Production Capacity In Obese Females, Oğuz Özçeli̇k, Hali̇l Doğan, Haluk Keleşti̇mur

Turkish Journal of Medical Sciences

The aim of this study was to examine the effects of weight loss induced by pharmacotherapy combined with a hypocaloric diet for a period of 8-weeks on maximal work (Wmax) production capacity and aerobic fitness in obese patients. Twelve obese females were put on an integrated energy restricted diet with orlistat supplement 3 x 120 mg/day. Each patient performed 3 incremental ramp exercise tests using an electromagnetically braked cycle ergometer: one at onset, one at the end of 4-weeks and one at the end of the 8-weeks to determine Wmax production capacity. The first 4-week therapy period resulted in a …

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Detection And Mapping Of Quantitative Trait Loci That Determine Responsiveness, Janet L. Mueller, E. A. Ellenberger, Linda K. Vaughn, John K. Belknap, Raymond M. Quock Jan 2004

Detection And Mapping Of Quantitative Trait Loci That Determine Responsiveness, Janet L. Mueller, E. A. Ellenberger, Linda K. Vaughn, John K. Belknap, Raymond M. Quock

Biomedical Sciences Faculty Research and Publications

Exposure to 70% N2O evokes a robust antinociceptive effect in C57BL/6 (B6) but not in DBA/2 (D2) inbred mice. This study was conducted to identify quantitative trait loci (QTL) in the mouse genome that might determine responsiveness to N2O. Offspring from the F2 generation bred from B6 and D2 progenitors exhibited a broad range of responsiveness to N2O antinociception as determined by the acetic acid-induced abdominal constriction test. QTL analysis was then used to dissect this continuous trait distribution into component loci, and to map them to broad chromosomal regions. To this end, …

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