Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- COVID-19 (110)
- Children (97)
- Oxidative stress (90)
- Inflammation (65)
- Rat (62)
-
- Mortality (59)
- Treatment (57)
- Turkey (57)
- Breast cancer (51)
- Prognosis (51)
- Pregnancy (49)
- Apoptosis (47)
- Prevalence (47)
- Magnetic resonance imaging (46)
- Obesity (46)
- Diabetes mellitus (37)
- Quality of life (36)
- Risk factors (36)
- Diagnosis (34)
- Nitric oxide (32)
- Ultrasonography (32)
- Rheumatoid arthritis (31)
- Epidemiology (30)
- Asthma (29)
- Hypertension (29)
- Reliability (29)
- Child (28)
- Validity (28)
- Depression (26)
- Diabetes (26)
- Publication Year
Articles 391 - 420 of 4871
Full-Text Articles in Medical Sciences
The Potential Mechanism Of Treating Ic/Bps With Hyperbaric Oxygen By Reducing Vascular Endothelial Growth Inhibitor And Hypoxia-Inducible Factor-1Α, Jing Zhang, Jiarui Kang, Liyang Wu
The Potential Mechanism Of Treating Ic/Bps With Hyperbaric Oxygen By Reducing Vascular Endothelial Growth Inhibitor And Hypoxia-Inducible Factor-1Α, Jing Zhang, Jiarui Kang, Liyang Wu
Turkish Journal of Medical Sciences
To investigate the roles of vascular endothelial growth inhibitor (VEGI) and hypoxia-inducible factor-1α (HIF-1α) in the treatment of refractory interstitial cystitis/bladder pain syndrome (IC/BPS) with hyperbaric oxygen (HBO).Materials and methods: A total of 38 patients were included. They were assessed before and 6 months after HBO treatment. Three- day voiding diaries were recorded, and O’leary-Sant scores, visual analog scale (VAS) scores, quality of life (QoL) scores, pelvic pain, and urgency/frequency (PUF) scores were evaluated. Bladder capacity was assessed by cystoscopy. Bladder mucosa was collected for Western blot, qRT-PCR, and immunofluorescence staining to compare the expression of VEGI and HIF-1α before …
Leaky Gut And Inflammatory Biomarkers In A Medication Overuse Headache Model In Male Rats, Doğa Vuralli, Hale Gök Dağidir, Elif Abbasoğlu Topa, Hayrunnisa Bolay Belen
Leaky Gut And Inflammatory Biomarkers In A Medication Overuse Headache Model In Male Rats, Doğa Vuralli, Hale Gök Dağidir, Elif Abbasoğlu Topa, Hayrunnisa Bolay Belen
Turkish Journal of Medical Sciences
Medication overuse is common among chronic migraine patients and nonsteroidal antiinflammatory drugs (NSAIDs)are the most frequently overused drugs. The pathophysiological mechanisms underlying medication overuse headache (MOH) are notcompletely understood. Intestinal hyperpermeability and leaky gut are reported in patients using NSAIDs. The aim of the study is toinvestigate the role of leaky gut and inflammation in an MOH model MOH model in male rats.Methods: The study was conducted in male Sprague Dawley rats. There were two experimental groups. The first group was the chronicNSAID group in which the rats received mefenamic acid (n = 8) for four weeks intraperitoneally (ip) and …
Evaluation Of Eye And Serum Findings In Different Waters In Rabbits By Drowning And Submersion Modeling, Aziz Yilmaz, Erdem Hösükler, Abdulgani Kaymaz, Ahmet Yücel Üçgül, Zehra Zerrin Erkol
Evaluation Of Eye And Serum Findings In Different Waters In Rabbits By Drowning And Submersion Modeling, Aziz Yilmaz, Erdem Hösükler, Abdulgani Kaymaz, Ahmet Yücel Üçgül, Zehra Zerrin Erkol
Turkish Journal of Medical Sciences
This study investigated serum, vitreous, and anterior chamber fluid electrolyte changes, corneal thickness (CT),corneal volume (CV), anterior chamber volume (ACV), and anterior chamber depth (ACD) as an auxiliary diagnostic method in theidentification of drowning in fresh or salt water.Materials and methods: The study used 35 healthy, adult, male, white New Zealand rabbits, seperated into five groups (control, saltwaterdrowning (SWD), saltwater immersion (SWI), freshwater drowning (FWD), freshwater immersion (FWI)). CT, CV, ACV, and ACDmeasurements were made with Pentacam topography at 0, 2, and 4 h in all groups. Magnesium (mg), sodium (Na), and chlorine (Cl)were measured in the blood at 0 …
Effect Of Humic Acid On Oxidative Stress And Neuroprotection In Traumatic Spinal Cord Injury: An Experimental Study, Burak Kinali, Nail Özdemi̇r, Ali Karadağ, Özge Kaya Korkmaz, Ayşe Gülden Di̇ni̇z, Fatma Demet Arslan
Effect Of Humic Acid On Oxidative Stress And Neuroprotection In Traumatic Spinal Cord Injury: An Experimental Study, Burak Kinali, Nail Özdemi̇r, Ali Karadağ, Özge Kaya Korkmaz, Ayşe Gülden Di̇ni̇z, Fatma Demet Arslan
Turkish Journal of Medical Sciences
Traumatic spinal cord injury (TSCI) is an important health problem, especially in developing countries withadditional socioeconomic loss. Humic acid (HA) usually has antioxidant, antiinflammatory, blood circulating, and antiviral effects.Hence, it was aimed herein to show the effect of HA on neuroprotection in a TSCI model.Materials and method: A TSCI model was used, in which 24 Wistar albino rats were divided into 4 groups: control group: subjectedto only laminectomy; sham group: subjected to laminectomy + TSCI; HA 5 mg/kg group: subjected to laminectomy + TSCI +intraperitoneal (IP) injection of 5 mg/kg of HA; and HA 10 mg/kg group: subjected to laminectomy …
Effects Of Glutamine And Omega-3 Fatty Acids On Intestinal Neomucosa Formation On Colon Serosa In Rats, Mehmet Köstek, Uygar Demi̇r, Ramazan Uçak, Burak Yasin Avci, Aydın Ünal, Osman Bilgin Gülçi̇çek, Ozan Çalişkan, Bülent Çi̇tgez, Erdinç Seri̇n, Sıtkı Gürkan Yetki̇n, Mehmet Mi̇hmanli, Mehmet Uludağ
Effects Of Glutamine And Omega-3 Fatty Acids On Intestinal Neomucosa Formation On Colon Serosa In Rats, Mehmet Köstek, Uygar Demi̇r, Ramazan Uçak, Burak Yasin Avci, Aydın Ünal, Osman Bilgin Gülçi̇çek, Ozan Çalişkan, Bülent Çi̇tgez, Erdinç Seri̇n, Sıtkı Gürkan Yetki̇n, Mehmet Mi̇hmanli, Mehmet Uludağ
Turkish Journal of Medical Sciences
Intestinal neomucosa formation is a technique defined for the treatment of short bowel syndrome. This study evaluates the effect of glutamine and omega-3 fatty acids on the growth of intestinal neomucosa on the colonic serosal surface has been evaluated.Materials and methods: Thirty-two adult male Sprague-Dawley rats were randomly divided into 4 groups: sham, control, glutamine, and omega-3. Laparotomy was performed on all groups. For rats other than the sham group, a 1-cm full-thickness incision was made 4 cm proximal to the ileocecal valve, and colonic serosal surface was sutured as a serosal patch over these openings. By using the oral …
Evaluation Of Baseline F-18 Fdg Positron Emission Tomography In The Diagnosis And Assessment Of Giant Cell Arteritis, Burak İnce, Emine Göknur Işik, Zeynep Gözde Özkan, Yasemin Yalçinkaya, Bahar Artım Esen, Ahmet Gül, Murat İnanç
Evaluation Of Baseline F-18 Fdg Positron Emission Tomography In The Diagnosis And Assessment Of Giant Cell Arteritis, Burak İnce, Emine Göknur Işik, Zeynep Gözde Özkan, Yasemin Yalçinkaya, Bahar Artım Esen, Ahmet Gül, Murat İnanç
Turkish Journal of Medical Sciences
The aim of this study is to evaluate the baseline F18-FDG PET/CT findings of individuals diagnosed with giant cellarteritis (GCA) and to explore its association with clinical findings and classification criteria.Materials and methods: We analysed data from patients who underwent F18-FDG PET/CT scans to investigate large vessel (LV)involvement between 2010 and 2019. Only patients with a clinical diagnosis of GCA and at least 6 months of follow-up were included.We compared initial clinical features and laboratory findings based on the presence of LV vasculitis on PET/CT and the maximumstandard uptake value (SUVmax) of vascular territories.Results: Twenty-nine patients (median age at diagnosis: …
A Retrospective Study On The Clinical And Molecular Outcomes Of Calpainopathy In A Turkish Patient Cohort, İzem Olcay Şahi̇n, Emine Karataş, Mikail Demi̇r, Büşra Tan, Hüseyin Per, Yusuf Özkul, Munis Dündar
A Retrospective Study On The Clinical And Molecular Outcomes Of Calpainopathy In A Turkish Patient Cohort, İzem Olcay Şahi̇n, Emine Karataş, Mikail Demi̇r, Büşra Tan, Hüseyin Per, Yusuf Özkul, Munis Dündar
Turkish Journal of Medical Sciences
Calpainopathy, also known as limb-girdle muscular dystrophy recessive type 1, is a progressive muscle disorder that impacts the muscles around the hips and shoulders. The disease is caused by defects in the CAPN3 gene and can be inherited in both recessive and dominant forms. In this retrospective study, we aimed to evaluate the clinical and molecular results of our patients with calpainopathy and to examine the CAPN3 variants in Turkish and global populations.Materials and methods: Molecular analyses were performed using the next-generation sequencing (NGS) method. CAPN3 variants were identified through the examination of various databases.Results: In this retrospective study, the …
The Effects Of On-Pump And Off-Pump Coronary Artery Bypass Surgery On Oxidative Stress And Cerebral Oxygenation: A Prospective Observational Study, Ökkeş Hakan Mi̇ni̇ksar, Sameh Alagha, Ferit Çi̇çekçi̇oğlu, Mehtap Honca, Ayşe Yeşim Göçmen
The Effects Of On-Pump And Off-Pump Coronary Artery Bypass Surgery On Oxidative Stress And Cerebral Oxygenation: A Prospective Observational Study, Ökkeş Hakan Mi̇ni̇ksar, Sameh Alagha, Ferit Çi̇çekçi̇oğlu, Mehtap Honca, Ayşe Yeşim Göçmen
Turkish Journal of Medical Sciences
In this prospective observational study, our goal was to investigate the relationship between serum levels of oxidative stress (OS) parameters and regional cerebral oxygen saturation (rSO2) in addition to evaluating postoperative clinical outcomes among patients undergoing coronary artery bypass graft surgery (CABG).Materials and methods: This study comprised 64 adult patients undergoing elective CABG (on-pump [n = 48] and off-pump [n = 16]) procedures. Serum OS levels and rSO2 values were measured intraoperatively at three specific time points: T1 (after induction), T2 (15 min before aortic cross-clamp removal or the final distal anastomosis), and T3 (15 min after aortic cross-clamp removal …
Does The Pleth Variability Index Have Any Predictive Value For Intraoperative Respiratory Problems In Bariatric Surgery?, Esra Özayar, Mehmet Şahap, Handan Güleç, Aysun Kurtay, Adem Selvi̇, Hakan Buluş, Özlem Ari
Does The Pleth Variability Index Have Any Predictive Value For Intraoperative Respiratory Problems In Bariatric Surgery?, Esra Özayar, Mehmet Şahap, Handan Güleç, Aysun Kurtay, Adem Selvi̇, Hakan Buluş, Özlem Ari
Turkish Journal of Medical Sciences
We aimed to search the relationship between the preoperative PVI (pleth variability index) and intraoperative respiratory parameters to reveal whether PVI can be used as a prediction tool in bariatric surgery.Materials and methods: Forty patients undergoing bariatric surgery were included. Noninvasive pleth variability index measured via finger probe before induction of general anesthesia. Following intubation each patient was ventilated in controlled mode. Intraoperative blood pressure, peak airway pressure, end-tidal CO2, SpO2, PEEP, and FiO2 were recorded every 5 min for the first 10 min and then every 10 min until extubation. Steroid and bronchodilator requirements were recorded.Results: The systolic pressure-PVI, …
The Effect Of Erector Spinae Plane Block On Postoperative Extubation Time And Laboratory Parameters In Open Heart Surgery: A Retrospective Study, Feyza Çalişir, Yavuz Orak, Ömer Faruk Boran, Metin Ege, Mehmet Emin Karabeki̇roğlu, Hilal Bi̇radli, Adem Doğaner
The Effect Of Erector Spinae Plane Block On Postoperative Extubation Time And Laboratory Parameters In Open Heart Surgery: A Retrospective Study, Feyza Çalişir, Yavuz Orak, Ömer Faruk Boran, Metin Ege, Mehmet Emin Karabeki̇roğlu, Hilal Bi̇radli, Adem Doğaner
Turkish Journal of Medical Sciences
In open heart surgery, sternotomy causes inflammation in tissues, and inflammation causes postoperative pain. This study aims to examine the effects of bilateral erector spinae plane (ESP) blocks on postoperative extubation time and laboratory parameters in open heart surgery.Materials and methods: The study was managed using retrospective data from 85 patients who underwent open-heart surgery. Patients who received intravenous analgesia and were transferred to the intensive care unit with intubation were included in the study. Two groups were formed: those who received preoperative bilateral ESP block (ESB) and those nonblock (NB). Statistical significance was investigated between ESB and NB in …
Survival Benefit Of Resin Cartridge Extracorporeal Blood Purification Therapy In Patients With Septic Shock, Serdar Efe, Pervin Hanci, Volkan İnal
Survival Benefit Of Resin Cartridge Extracorporeal Blood Purification Therapy In Patients With Septic Shock, Serdar Efe, Pervin Hanci, Volkan İnal
Turkish Journal of Medical Sciences
Extracorporeal blood purification (EBP) therapies have shown promise as potential rescue treatments for patientswith septic shock. However, precise evidence regarding their effectiveness is lacking. This case-control study aimed to evaluate the 28-day survival benefit of a resin cartridge-based EBP therapy compared to conventional therapies in patients with septic shock.Materials and methods: The study sample was collected retrospectively from the medical records of patients admitted to the intensivecare unit (ICU) between 2015 and 2020. The study included patients with septic shock aged ≥18 years who had ICU stays >96 h andexcluded those lost to follow-up by 28 days or readmitted. First, …
Reliability And Validity Of New Isokinetic Strength Assessment For Rotator Cuff Muscles In A Muscle Architecture-Based Position, Çağlar Soylu, Mustafa Ertuğrul Yaşa, Pervin Demi̇r, Ahmet Mustafa Ada, Tüzün Firat, Necmiye Ün Yildirim
Reliability And Validity Of New Isokinetic Strength Assessment For Rotator Cuff Muscles In A Muscle Architecture-Based Position, Çağlar Soylu, Mustafa Ertuğrul Yaşa, Pervin Demi̇r, Ahmet Mustafa Ada, Tüzün Firat, Necmiye Ün Yildirim
Turkish Journal of Medical Sciences
Isokinetic strength assessment of the rotator cuff muscle is frequently applied in a variety of shoulder postures, butnone of these consider muscular architecture, which is one of the most important aspects of improving strength development. This studyaimed to examine the test and retest reliability and validity of the muscle architecture-based position (MABP), which is 25° abductionand 20° external rotation, in healthy subjects to be able to select a better isokinetic assessment position for shoulder rotator cuff muscles.Materials and methods: A total of 54 healthy males with a mean age of 21.0 ± 1.2 years and mean body mass index of …
The Effect Of Video-Assisted Training On Upper Extremity Problems And Functions After Rotator Cuff Repair: A Randomized Controlled Trial, Canan Kanat, Gülay Altun Uğraş, Recep Ünal, Servet Can Dönmez, Bahar Taşdelen, Fehmi Volkan Öztuna
The Effect Of Video-Assisted Training On Upper Extremity Problems And Functions After Rotator Cuff Repair: A Randomized Controlled Trial, Canan Kanat, Gülay Altun Uğraş, Recep Ünal, Servet Can Dönmez, Bahar Taşdelen, Fehmi Volkan Öztuna
Turkish Journal of Medical Sciences
The shoulder is the most mobile joint in the body, and is frequently exposed to injuries. The applied surgical treatments, protection of the shoulder after surgery, care in the use of the shoulder in activities of daily living (ADLs) and gradual exercise programs are all vital to the recovery process. The present study investigates the effect of video-assisted training (VAT) on upper extremity complications and functions after rotator cuff repair (RCR).Materials and method: Included in this prospective, parallel two-armed, randomized controlled study were an experimental group (n: 24) that received VAT detailing early postoperative care for RCR and instructions on …
Urologists’ Opinion On Treating Asymptomatic Stones: Would We Treat Ourselves As We Treat Our Patients? Survey From European Association Of Urology, Young Academicurologists, Endourology And Urolithiasis Working Party, Tarık Emre Şener, Thomas Tailly, Yılören Tanidir, Etienne Xavier Keller, Amelia Pietropaolo, Juan Gomez Rivas, Zeeshan Hameed, Vincent De Coninck, Tzevat Tefi̇k, Kemal Sarica, Ali Serdar Gözen, Andreas Skolarikos, Olivier Traxer, Christian Seitz, Bhaskar Somani
Urologists’ Opinion On Treating Asymptomatic Stones: Would We Treat Ourselves As We Treat Our Patients? Survey From European Association Of Urology, Young Academicurologists, Endourology And Urolithiasis Working Party, Tarık Emre Şener, Thomas Tailly, Yılören Tanidir, Etienne Xavier Keller, Amelia Pietropaolo, Juan Gomez Rivas, Zeeshan Hameed, Vincent De Coninck, Tzevat Tefi̇k, Kemal Sarica, Ali Serdar Gözen, Andreas Skolarikos, Olivier Traxer, Christian Seitz, Bhaskar Somani
Turkish Journal of Medical Sciences
Management of asymptomatic kidney stones is an ongoing debate with follow-up and treatment guidelines based on low-level evidence. Our aim was to evaluate current management of asymptomatic urinary stones.Materials and methods: A 70-question survey was designed in collaboration with European Association of Urology, Young Academic Urologists, Section of Uro-Technology and Section of Urolithiasis groups and distributed. Responders filled out hypothetical scenarios from 2 perspectives, either as treating physicians, or as patients themselves.Results: A total of 212 (40.01%) responses were obtained. Median responder age was 39 years. 75% of responders were interested in “urolithiasis”. 82.5% had never experienced a renal colic, …
Diurnal Rhythm Of Urinary Aquaporin-2 In Children With Primary Monosymptomatic Nocturnal Enuresis, Nehal Abdelhamid, Mohamed A. Abd Almawla, Aliaa A. Wahby, Mervat Ismail, Hani Abdelsalam Elmikaty, Hanan M. Hamed, Ingy Ashmawy, Bataul Mohamed Abdelraoaf, Enas Mokhtar Abdelhamid, Hassan M. Salam
Diurnal Rhythm Of Urinary Aquaporin-2 In Children With Primary Monosymptomatic Nocturnal Enuresis, Nehal Abdelhamid, Mohamed A. Abd Almawla, Aliaa A. Wahby, Mervat Ismail, Hani Abdelsalam Elmikaty, Hanan M. Hamed, Ingy Ashmawy, Bataul Mohamed Abdelraoaf, Enas Mokhtar Abdelhamid, Hassan M. Salam
Turkish Journal of Medical Sciences
Nocturnal enuresis can be frustrating for children and their families as the child ages. Our aim is to evaluate urine aquaporin 2 (AQP-2) as a noninvasive biomarker of water balance in children with primary monosymptomatic nocturnal enuresis (PMNE).Material and methods: The study included 90 children; sixty-eight children suffering from PMNE aged (9.57 ± 2.16) years and 22 healthy children with good toilet control, matched sex and age. All enuretic children were subjected to complete history taking, clinical evaluation, and bed wetting diary. Serum arginine vasopressin (AVP) and urine AQP-2 were tested in the morning (at 9–11 am) and evening (at …
Evaluation Of The Aquaporin Molecules Characterization In The Sperm Cells Of Men From Different Aged, Fikret Gevrek, Osman Serden Gencel, Selim Görgün, Mikail Kara, Muzaffer Katar
Evaluation Of The Aquaporin Molecules Characterization In The Sperm Cells Of Men From Different Aged, Fikret Gevrek, Osman Serden Gencel, Selim Görgün, Mikail Kara, Muzaffer Katar
Turkish Journal of Medical Sciences
Male infertility rises for many reasons, along with age; therefore, we aimed to research the characterization of aquaporin-3, 7, and 8 in human sperm belonging to different age groups. Material and methods: This study was conducted on sperm samples of men aged over 18 years. A total of 60 men were included in the study and divided into three age groups: group 1, age 18–25 years (n = 20); group 2, age 26–35 years (n = 20); and group 3, age ≥35 years (n = 20). Sperm ejaculates obtained from each participant were used for spermiogram tests, Kruger strict morphology …
Comparison Of The Clinical Efficacy Of Ultrasound-Guided Gon Blockade Using Low And High Concentrations Of Bupivacaine In Chronic Migraine, Ümit Murat Parpucu, Onur Küçük, Fatih Sağ, Suna Akın Takmaz, Barış Kiran, İsmail Eren Durmuş, Yılmaz Karaduman, Semih Aydemi̇r
Comparison Of The Clinical Efficacy Of Ultrasound-Guided Gon Blockade Using Low And High Concentrations Of Bupivacaine In Chronic Migraine, Ümit Murat Parpucu, Onur Küçük, Fatih Sağ, Suna Akın Takmaz, Barış Kiran, İsmail Eren Durmuş, Yılmaz Karaduman, Semih Aydemi̇r
Turkish Journal of Medical Sciences
In this study, it was aimed to retrospectively compare the effect of greater occipital nerve (GON) block performed with ultrasonography using low (0.3%) and high (0.5%) concentrations of bupivacaine on pain scores and patient satisfaction in chronic migraine (CM).Materials and methods: The mean number of days with pain, the mean duration of pain in the attacks, and the highest numerical rating scale (NRS) scores recorded in the 1 month preblock and 1 and 3 months postblock of 80 patients (40 for Group 1, 0.3% bupivacaine; 40 for Group 2, 0.5% bupivacaine) who underwent ultrasonography-guided GON block were recorded from the …
Sodium-Fluorescein-Guided Awake Surgery For Cerebral Metastases Located In Eloquent Brain Areas: Technical Notes And Preliminary Experiences, Alper Türkkan, Pınar Ocak, Marzieh Karimi Khezri, Ahmet Bekar
Sodium-Fluorescein-Guided Awake Surgery For Cerebral Metastases Located In Eloquent Brain Areas: Technical Notes And Preliminary Experiences, Alper Türkkan, Pınar Ocak, Marzieh Karimi Khezri, Ahmet Bekar
Turkish Journal of Medical Sciences
Awake craniotomy (AC) maximizes the resection of lesions in eloquent brain areas while preserving functionality.Tumor delineation with intraoperative use of sodium fluorescein (NaFl) facilitates total resection. When used with AC, it may allowfor safe resection without increasing the risk of postoperative neurologic deficits. This study investigated the efficacy and safety of thecombined use of NaFl and AC for maximum safe resection in patients with brain metastases.Material and methods: Patients who underwent AC due to brain metastasis in the Department of Neurosurgery of Uludağ University’sFaculty of Medicine between January 1, 2018 and August 1, 2022, were retrospectively analyzed. The study comprised …
Predicting Difficult Airway In Morbidly Obese Patients Using Ultrasound, Sevim Akin, Mustafa Yildirim, Hakan Artaş, Esef Bolat
Predicting Difficult Airway In Morbidly Obese Patients Using Ultrasound, Sevim Akin, Mustafa Yildirim, Hakan Artaş, Esef Bolat
Turkish Journal of Medical Sciences
Difficult mask ventilation and difficult intubation are more common in obese patients. Ultrasound is a reliable andnoninvasive method for evaluating the airway. The aim of this study was to investigate the contribution and availability of anterior necksoft tissue (ANS) thickness at different levels, tongue volume (TV), hyomental distance (HMD), the ratio of preepiglottic distance todistance between the epiglottis and the midpoint of vocal cords (PE/E-VC) measured by ultrasonography in predicting difficult airwayin morbidly obese patients.Materials and methods: Between March 2020 and November 2020, patients aged ≥18 years with a body mass index (BMI) of ≥40 kg/m2who underwent elective surgery under …
Analysis Of Risk Factors And Changes In Myocardial Biomarker Levels In 122 Cases Of Early Neonatal Anemia, Zhenhua Sui
Analysis Of Risk Factors And Changes In Myocardial Biomarker Levels In 122 Cases Of Early Neonatal Anemia, Zhenhua Sui
Turkish Journal of Medical Sciences
Anemia in the first week after birth, which could affect growth, development, and organ function, should be an important warning sign to clinicians. The aim of this study was to assess the related risk factors of early neonatal anemia and to analyze the effect of anemia on the expression levels of myocardial markers in newborns.Materials and methods: Clinical data from 122 confirmed cases of anemic newborns and 108 nonanemic newborns were collected to analyze the independent risk factors for early anemia using logistic regression analyses. Blood samples were collected from both groups for the detection of myocardial markers, including the …
High Amniotic Fluid Fractalkine And Mip-1Β Levels Are Associated With Intrauterine Growth Restriction: A Prospective Cohort Study, Şehmus Pala, Remzi Atilgan, Nevin İlhan
High Amniotic Fluid Fractalkine And Mip-1Β Levels Are Associated With Intrauterine Growth Restriction: A Prospective Cohort Study, Şehmus Pala, Remzi Atilgan, Nevin İlhan
Turkish Journal of Medical Sciences
Proinflammatory chemokines have been shown to play crucial roles in implantation, spiral artery invasion, and thefetomaternal immunological response. In this context, we investigated the levels of fractalkine (CX3CL1) and chemokine CC motifligand 4 (CCL4 or MIP-1β) in maternal serum and amniotic fluids in pregnant women with intrauterine growth restriction (IUGR).Materials and methods: This prospective cohort study was carried out at Fırat University Obstetrics Clinic between January 1, 2022 andJuly 1, 2022. Group (G) 1: The control group consisted of 40 pregnant women who underwent elective cesarean section (CS) at 38–40weeks of gestation. G2: A total of 40 pregnant women with …
Risk Factors Of Congenital Nomalies Of The Kidney And Urinary Tract (Cakut): Exposureto Mobile Phones During Pregnancy, Kübra Çeleğen, Esra Özgül, Zeynep Yeşi̇ldağ, Erdem Yusuf Çamirci, Mehmet Çeleğen, Ayşegül Bükülmez
Risk Factors Of Congenital Nomalies Of The Kidney And Urinary Tract (Cakut): Exposureto Mobile Phones During Pregnancy, Kübra Çeleğen, Esra Özgül, Zeynep Yeşi̇ldağ, Erdem Yusuf Çamirci, Mehmet Çeleğen, Ayşegül Bükülmez
Turkish Journal of Medical Sciences
Congenital anomalies of the kidney and urinary tract(CAKUT) are the leading causes of childhood chronic kidney disease (CKD). The etiology of most of the cases is thought to be multifactorial. In this study, risk factors for CAKUT and the effect of mobile phone-related electromagnetic field (EMF) exposure during pregnancy were investigated.Materials and methods: Fifty-seven cases and 57 healthy controls under 2 years of age were included and their mothers were subjected to a questionnaire. Groups were compared for parents’ demographics, pregestational (chronic disease, body mass index, use of the folic acid supplements) and antenatal variables (gestational disease, weight gain during …
Predictive Values Of Mallampati Score, Tonsillar Size, And Bmi Z-Score In The Presence And Severity Of Obstructive Sleep Apnea In Pediatric Population, Ayşe Kaçar Bayram, Ahu Paketçi̇, Melek Nur Şahbaz, Sevde Daşdelen, Serkan Bilge Koca
Predictive Values Of Mallampati Score, Tonsillar Size, And Bmi Z-Score In The Presence And Severity Of Obstructive Sleep Apnea In Pediatric Population, Ayşe Kaçar Bayram, Ahu Paketçi̇, Melek Nur Şahbaz, Sevde Daşdelen, Serkan Bilge Koca
Turkish Journal of Medical Sciences
Obstructive sleep apnea (OSA) is a common sleep-related breathing disorder in children. Determination of riskfactors for the development of OSA is essential for early diagnosis and treatment of the disease and decreases the risk of negativeconsequences. This study aimed to investigate the predictive values of Mallampati score, tonsillar size, and BMI z-score in the presenceand severity of OSA in children.Materials and methods: This prospective cross-sectional study included 114 children with OSA symptoms. All children were assessedby BMI z-score, Mallampati score, and tonsillar size and underwent overnight polysomnography. They were consecutively selected andassigned to 4 groups as follows: Group 1 included …
Elderly And Aged Asthma Have Different Characteristics: Results Of A Multicenter Study, Ebru Damadoğlu, Özge Öztürk Aktaş, Bilun Gemi̇ci̇oğlu, Nafiye Yilmaz, Fulşen Bozkuş, Vehbi Ayhan, Ayşe Füsun Kalpaklioğlu, Ferda Öner Erkekol, Yavuz Havlucu, Fuat Erel, Ömür Aydin, Aydanur Eki̇ci̇, Ayşe Baççioğlu, Serap Argun Bariş, Gözde Köycü Buhari̇, Berrin Ceyhan, Özlem Göksel, Mehmet Köse, Adile Berna Dursun, Füsun Yildiz, Arzu Yorgancioğlu, Sacide Rana Işik, Dane Edi̇ger, İpek Kıvılcım Oğuzülgen, Ahmet Uğur Demi̇r, Gül Karakaya, Ali Fuat Kalyoncu
Elderly And Aged Asthma Have Different Characteristics: Results Of A Multicenter Study, Ebru Damadoğlu, Özge Öztürk Aktaş, Bilun Gemi̇ci̇oğlu, Nafiye Yilmaz, Fulşen Bozkuş, Vehbi Ayhan, Ayşe Füsun Kalpaklioğlu, Ferda Öner Erkekol, Yavuz Havlucu, Fuat Erel, Ömür Aydin, Aydanur Eki̇ci̇, Ayşe Baççioğlu, Serap Argun Bariş, Gözde Köycü Buhari̇, Berrin Ceyhan, Özlem Göksel, Mehmet Köse, Adile Berna Dursun, Füsun Yildiz, Arzu Yorgancioğlu, Sacide Rana Işik, Dane Edi̇ger, İpek Kıvılcım Oğuzülgen, Ahmet Uğur Demi̇r, Gül Karakaya, Ali Fuat Kalyoncu
Turkish Journal of Medical Sciences
Characteristics of asthma in the elderly population is not well-known. The aim of the present study was to evaluateasthma in the elderly population, to compare disease characteristics between patients diagnosed <60 (aged asthma) and ≥60 (elderlyasthma) years of age.Materials and methods: The study was a prospective, multicenter, cross-sectional type. A questionnaire was filled out to patients 60years of age and over, that have been followed for asthma for at least 3 months. Asthma Control Test (ACT), eight-item MoriskyMedication Adherence Scale (MMAS-8) was filled out, inhaler device technique was assessed.Results: A total of 399 patients were included from 17 tertiary care centers across the country. Mean age was 67.11 years and 331 (83%)were female. The age at asthma diagnosis was ≥60 in 146 (36.6%) patients. Patients diagnosed ≥60 years were older (p < 0.001), hadhigher education level (p < 0.001), more commonly had first-degree relative with asthma (p = 0.038), asthma related comorbidities(p = 0.009) and accompanying rhinitis/rhinosinusitis (p = 0.005), had better asthma control (p = 0.001), were using less controllermedications (p = 0.014). Inhaler technique was correct in 37% of the patients with no difference in between the groups. Treatmentcompliance was better in elderly asthma patients (p < 0.001). In the multivariate logistic regression analysis, having well-controlledasthma (odds ratio = 1.61, CI = 1.04–2.51), and high medication adherence rate (odds ratio = 2.43, CI = 1.48–4.0) were associated withbeing in the elderly asthma group.Conclusion: The characteristics of asthma are different among patients aged 60 years and over which seems to be related to onset age ofasthma. In our cohort, the elderly asthma patients had higher education level, and treatment adherence and asthma control was better.Patients diagnosed ≥60 years of age did not have more severe disease.
Evaluation Of Bone Health In Terms Of Osteoporosis In Adult Patients With Neuromuscular Disease, Özgür Zeliha Karaahmet, Eda Gürçay, Yasemin Tombak Yildizkan, Damla Cankurtaran, Zeynep Tuba Bahti̇yarca, Ebru Umay
Evaluation Of Bone Health In Terms Of Osteoporosis In Adult Patients With Neuromuscular Disease, Özgür Zeliha Karaahmet, Eda Gürçay, Yasemin Tombak Yildizkan, Damla Cankurtaran, Zeynep Tuba Bahti̇yarca, Ebru Umay
Turkish Journal of Medical Sciences
There are no current guidelines to help clinicians decide whether patients with adult neuromuscular disease (NMD) should be screened or treated for osteoporosis (OP). This study was undertaken to investigate the presence of OP in patients with various types of NMD and to examine the relationship between OP evaluation parameters and functional status, daily living activities, balance, and ambulation levels.Materials and methods: This cross-sectional study included 45 patients with NMDs. The patients were divided into 3 groups, depending on the affected component of the motor unit (neuronopathy group, neuropathy group, and myopathy group). The laboratory and demographic data were recorded …
Minipuberty Period Of Children With Atopic Dermatitis Compared To Healthy Children, Serkan Bilge Koca, Hatice Eke Güngör, Murat Cansever
Minipuberty Period Of Children With Atopic Dermatitis Compared To Healthy Children, Serkan Bilge Koca, Hatice Eke Güngör, Murat Cansever
Turkish Journal of Medical Sciences
Atopic dermatitis (AD) is an inflammatory, pruritic, noncontagious, chronic relapsing skin disease. Skin barrierabnormalities, excessive T helper 2 activity, and immune dysregulation are held responsible. Androgens have a negative effect on theintegrity of the epidermal skin barrier, while estrogen has a positive effect. We aimed to investigate whether hormones make a differencebetween healthy children and children with AD during minipuberty.Materials and methods: A total of 96 infants (postnatal 4–13 weeks), 48 diagnosed with AD and 48 controls, were included. Each groupconsisted of 23 girls (47.9%) and 25 boys (52.1%). Anthropometric examinations and hormone measurements were compared.Results: The two groups, having …
Psychometric Properties Of T E Canadian Occupational Performance Measure In Older Individuals, Onur Altuntaş, Medine Nur Özata Değerli̇, Ege Temi̇zkan, Gamze Eki̇ci̇
Psychometric Properties Of T E Canadian Occupational Performance Measure In Older Individuals, Onur Altuntaş, Medine Nur Özata Değerli̇, Ege Temi̇zkan, Gamze Eki̇ci̇
Turkish Journal of Medical Sciences
The Canadian Occupational Performance Measure (COPM) is a person-centered assessment tool frequently used to identify occupational problems in older individuals and establish goals for geriatric rehabilitation. This study aims to assess the validity and reliability of the Turkish version of COPM (COPM-TR) in older people.Materials and methods: One hundred older people completed the COPM-TR, and 25 of them participated in a retest within two weeks. The convergent construct validity analyses of the COPM-TR included conducting correlation analyses between the COPM-TR and the Functional Independence Measure (FIM) and Lawton Brody Instrumental Activities of Daily Living (Lawton-IADL) scales. The Performance and Satisfaction …
The Role Of Probiotics For Preventing Dysbiosis In Periodontal Disease: A Randomized Controlled Trial, Tuğba Şahi̇n, Gülçin Akca, Nurdan Özmeri̇ç
The Role Of Probiotics For Preventing Dysbiosis In Periodontal Disease: A Randomized Controlled Trial, Tuğba Şahi̇n, Gülçin Akca, Nurdan Özmeri̇ç
Turkish Journal of Medical Sciences
Scaling and root planing remain inadequate in periodontitis treatment caused by dysbiotic microbial dental plaque. The aim of this clinical trial is to evaluate the effects of probiotics and kefir consumption in initial periodontal therapy (IPT) on oral microbiota composition and treatment outcomes in patients with periodontitis.Materials and methods: The study was carried out in the Gazi University Department of Periodontology, including a sample size of 36 individuals and utilizing a randomized controlled design. Thirty-six patients with periodontitis were randomly allocated to three groups: one receiving probiotic treatment, another receiving kefir, and a third serving as the control group. Obtaining …
Is Gut Microbiota Of Patients With Als Different From That Of Healthy Individuals?, Zeri̇n Özaydin Aksun, Seyda Erdoğan, Ayşe Kalkanci, Eli̇f Ayça Şahi̇n, Tuğba Çuhadar, H. Özden Şener
Is Gut Microbiota Of Patients With Als Different From That Of Healthy Individuals?, Zeri̇n Özaydin Aksun, Seyda Erdoğan, Ayşe Kalkanci, Eli̇f Ayça Şahi̇n, Tuğba Çuhadar, H. Özden Şener
Turkish Journal of Medical Sciences
Background/aim: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease. Several studies shown that alterations of microbiota, increase the risk of neurodegenerative disorders. We aimed to reveal whether there is a difference in the gut microbiota of patients with ALS.Materials and methods: The participants are divided into three groups. Group 1 formed patients with ALS. Healthy family members living in the same house of the patients formed Group 2. Lastly, sex, age-matched healthy people were included in Group 3. Fecal samples were collected in 15 mL falcon tubes and stored at -80 °C. Genomic DNA isolation was performed on samples. …
Association Of Gait Speed And Handgrip Strength With Falls In Older Adults: The Role Of Cognition, Nesli̇han Kayahan Satiş, Sultan Keski̇n Demi̇rcan, Mehmet İlki̇n Naharci
Association Of Gait Speed And Handgrip Strength With Falls In Older Adults: The Role Of Cognition, Nesli̇han Kayahan Satiş, Sultan Keski̇n Demi̇rcan, Mehmet İlki̇n Naharci
Turkish Journal of Medical Sciences
Background/aim: Fall risk assessment is crucial for older adults because falls are associated with morbidity and mortality. This study investigated the relationship of gait speed (GS) and handgrip strength (HGS) with falls and assessed whether cognition mediates this causality.Materials and methods: The study was conducted in a tertiary referral geriatric outpatient clinic. The physical performance of participants was evaluated by GS and HGS. All falls the previous year were noted and factors associated with falls were analyzed using multivariate regression analysis.Results: A total of 1,018 older adults, with a mean age of 78.8 years (±7.2), of whom 64.2% were female, …