Diseases Commons^™

The Essentials Of Heart Failure Management, Emily W. Greene

Doctor of Nursing Practice Projects

Heart failure remains a leading cause of hospitalization among older adult women, often due to delayed recognition of symptom exacerbation and limited knowledge of self-management strategies. The purpose of this quality improvement project was to evaluate whether a brief educational intervention could improve knowledge of heart failure management among older adult women at a community senior center. The DNP project leader conducted two educational sessions focusing on early recognition of heart failure symptoms, heart-healthy diet, and when to contact a healthcare provider. Participants completed a pre- and post-test survey containing four knowledge questions and one Likert-scale question on perceived knowledge …

Procedural-Based Contemporary Management Of Bell's Palsy Long-Term Sequelae: A Narrative Review, Robert M. Frederick, Rhorie Kerr, Eric Dobratz, William Dougherty

Department of Otolaryngology (ENT) Faculty Publications

Objective

To describe the long-term sequelae of Bell's palsy and summarize available treatment options, including recent advances, so that general otolaryngologists and other practitioners are aware of the clinical findings and available interventions.

Data Sources

PubMed.

Review Methods

A literature search was performed on December 18, 2024, via PubMed using keywords such as "synkinesis," "selective myectomy," "selective neurectomy," "botulinum toxin," "intervention" in the context of "Bell's palsy" with preference for articles published within the last 5 to 10 years but inclusion of select older articles that provided necessary context for the current topic. Articles included in the review were written …

Differences In Biologic Clinical Trials For Chronic Rhinosinusitis With Nasal Polyps—Are We Comparing Apples With Oranges?, Marjolein Cornet, Peter W. Hellings, Martin Desrosiers, Martin Wagenmann, Richard Follows, Laura Walrave, Luz Adriana Jimenez, Lee Tombs, Dawn Edwards, Peter Howarth, Joseph K. Han

Department of Otolaryngology (ENT) Faculty Publications

In recent years, several biologics targeting Type 2 inflammation have been developed for treating chronic rhinosinusitis with nasal polyps (CRSwNP). These have been studied in registrational randomized controlled trials (RCTs), which vary in their patient populations, trial design, endpoints, geography, timing, or data-handling processes. While (in)direct treatment comparisons and meta-analyses have been carried out to compare efficacy results from RCTs, often these fail to properly account for these between-study differences. Here, we summarize the key between-study differences that can influence trial outcomes and highlight the resulting challenges faced when comparing outcomes from different Phase III RCTs of biologics in CRSwNP.

Establishment Of A Conditionally Replicating Guinea Pig Cytomegalovirus Model For Molecular Characterization Of Latency, Akshay R. Molakalapalli, Saketh Majeti, Michael A. Mcvoy, Jian Ben Wang

Undergraduate Research Posters

Human cytomegalovirus (HCMV) is a member of the Herpesviridae that establishes life-long latent infections that pose risks of life-threatening disease upon reactivation in immunocompromised individuals. Understanding the molecular mechanisms that govern the latent state is critical for developing effective treatments. However, molecular characterization has been impeded by the scarcity of latently infected cells in vivo and the inability of current in vitro models to support the expansion of clonal latent cell lines. To address these limitations, we developed a novel cell culture model utilizing a conditionally replicating guinea pig cytomegalovirus, a relative of HCMV that mimics HCMV pathology and provides …

Initiation, Timing, And Duration Of Prone Positioning In Icu Ards Patients: An Integrative Research Review (Irr), Amanda Everard Thomas

Covenant Nurses Week 2026

No abstract provided.

Hapi Heroes Initiative: Innovating Patient Turn Strategies Utilizine The Braden Scale To Prevent Hospital Acquired Pressure Injuries (Hapi) In The Cardiac Telemetry Unit-A Reposition Disposition Quality Improvement Project, Kenn Everard Lachenal, Kimberlea Gale Hiett-Gonzales, Charmaine Capili, Jelly Jacob, Melissa Fallorina, Dillon Mckee

Covenant Nurses Week 2026

No abstract provided.

Longitudinal Changes In Plasma Biomarkers Of Immune Activation, Neuronal Inflammation And Injury In Persons With Hiv Initiating Art, Merle Henderson, Peter Dutey-Magni, Carolina Herrera, Wolfgang Stöhr, Alejandro Arenas-Pinto, Owen Swann, Amanda Heslegrave, Henrik Zetterberg, John Tregoning, Sarah Fidler, François Raffi, Andrea Calcagno, Ab Babiker, Alan Winston

CONRAD Publications

Background

Data on changes in biomarkers of brain health, and their associations with cognitive function in adults commencing either dual- or triple-antiretroviral therapy (ART) are sparse.

Methods

Plasma biomarkers (neurofilament light [NfL], glial fibrillary acidic protein [GFAP], sCD14, CXCL10, neopterin and IL-6) were measured at baseline and after 96 weeks on ART in individuals randomized to darunavir/ritonavir and either tenofovir-DF/emtricitabine (triple-ART, n = 119) or raltegravir (dual-ART, n = 119) in NEAT-001/ANRS143. Regression models examined associations of baseline and week-96 biomarker concentrations with HIV clinical parameters, composite cognitive test scores (Standardized neuropsychological test [NPZ], 7-domains) and treatment arm.

Results

In …

Comparative Analysis Of Serum-Free Culture Conditions On Cell Proliferation And Extracellular Vesicle Production By Adipose-Derived Stem Cells, Ayna Ghulldu

Honors Undergraduate Theses

Adipose-derived stem cells (ADSCs) are promising candidates in regenerative medicine due to their proliferative capacity, self-renewal, and secretion of extracellular vesicles (EVs) that mediate intercellular communication. Serum-free media has been increasingly explored for MSC culture as it eliminates xenogeneic components, improving human therapeutic suitability. However, comparative evaluation of distinct serum-free formulations on ADSC proliferation and EV output simultaneously remains limited. This study compares a serum-containing medium to three proprietary serum-free media prototypes differing in composition, including the presence or absence of extracellular matrix proteins, to inform the optimization of culture conditions for clinical use. Proliferation, EV characteristics, and gene expression …

Long-Term Incidence Trends And Stage Distribution Of Cutaneous Melanoma In The United States (1975–2022): A Seer Population-Based Analysis, Thea Danielle Amadasun, Shahzaib Maqbool

MidAmerica Division GME Healthcare Symposium 2026

No abstract provided.

Smarca4-Deficient Carcinoma Of The Gastroesophageal Junction, Hanna Riga, Austin Lehr

MidAmerica Division GME Healthcare Symposium 2026

No abstract provided.

A Rare Case Of New Onset Lisinopril-Induced Angioedema Improved With Tranexamic Acid: A Case Report, Hafiz Numan Ijaz, Shahzaib Maqbool, Yugandhar Kandimalla

MidAmerica Division GME Healthcare Symposium 2026

No abstract provided.

Atypical Del(5q) Mutation In Myelodysplastic Syndrome Presenting With Thrombocytopenia: A Case Report Of Tp53-Mutated High-Risk Biology, Shahzaib Maqbool, Munaf Siyamwala, Amelia Goslin, Shivani R. Scharf, Katsiaryna Laziuk

MidAmerica Division GME Healthcare Symposium 2026

No abstract provided.

Intestinal Tuberculosis Masquerading As Crohn’S Disease: A High-Risk Diagnostic Mimic, Maikel Tawadrous, Tejaswi Vadde, Subuhee Ahmed, Lawrence San Jose, Chelsea Curry, Aradhana Pandey

MidAmerica Division GME Healthcare Symposium 2026

No abstract provided.

High-Flow Ectatic Anomalous Right Coronary Artery From The Pulmonary Artery With Stimulant-Induced Cardiomyopathy: A Case Report, Prithvi Basu Roy, Danish Bawa, Louis Orlando

MidAmerica Division GME Healthcare Symposium 2026

No abstract provided.

From Focal Peroneal Neuropathy To Complex Regional Pain Syndrome: A Case Of Progressive Unilateral Lower Extremity Pain, Ali Haider, Yu-Shiuan Hsu

MidAmerica Division GME Healthcare Symposium 2026

No abstract provided.

Alpha 1 Antitrypsin Deficiency In Primary Care: A Case Presentation, John Sweetman, Gazala Parvin

MidAmerica Division GME Healthcare Symposium 2026

No abstract provided.

Intermittent Hypoxia In A Middle-Aged Woman With A Probable Bethlem Myopathy Carrier State And Suspected Complex Sleep-Related Hypoventilation, Jonathan Paul Ladera, Louis Orlando

MidAmerica Division GME Healthcare Symposium 2026

No abstract provided.

"Qt Okay, Bowel Not Okay"- Dofetilide Masking An Evolving Small-Bowel Obstruction, Tejaswini Yeshala, Pankti Shah, Syed Ali Abidi, Archana Machavarapu

MidAmerica Division GME Healthcare Symposium 2026

No abstract provided.

Esophageal Stents: How High Can You Go? A Traumatic Injury Treated With High Esophageal Stent Placement, John W. Surbeck, Anthony P. Melillo, James S. Scott

MidAmerica Division GME Healthcare Symposium 2026

No abstract provided.

Type 2 Myocardial Infarction In Adults Admitted For Severe Persistent Asthma With Status Asthmaticus: Evaluating Predictors And Mortality Burden, Kanwar Bir Dhaliwal, Rahul Pawa, Naresh Kodwani

MidAmerica Division GME Healthcare Symposium 2026

No abstract provided.

A Histopathological Mystery: A Rare Atypical Feature Of Microscopic Colitis, Mohammad Mahfouz, Pratyush Kumar, Kumar Abhishek, Archana Machavarapu

MidAmerica Division GME Healthcare Symposium 2026

No abstract provided.

Overcoming Resistance To Car T-Cell Therapy In Hematologic Malignancies: Mechanisms, Counter-Strategies, And The Emerging Triple-Threat Multi-Antigen Approach, Muhammed Salman Ullah

MidAmerica Division GME Healthcare Symposium 2026

No abstract provided.

Impact Of Pharmacist Intervention And Cardiac Rehab In Post-Acute Myocardial Infarction Patients On 90-Day Readmission Rates, Paige Hall, Jennifer Wong, Tricia Walsh

MidAmerica Division GME Healthcare Symposium 2026

No abstract provided.

Baseline Right Ventricular-Pulmonary Arterial Coupling As A Predictor Of Clinical Outcomes In Endobronchial Valve Therapy For Advanced Emphysema, Syed Ali Raza Abidi, Prithvi Basu Roy, Munaf Siyamwala, Amelia Goslin

MidAmerica Division GME Healthcare Symposium 2026

No abstract provided.

Efficacy And Safety Profile Of Busulfan Plus Low Dose Melphalan Versus High Dose Melphalan As A Conditioning Regimen For Autologous Hematopoietic Stem Cells Transplantation In Multiple Myeloma Patients, Shahzaib Maqbool, Munaf Siyamwala

MidAmerica Division GME Healthcare Symposium 2026

No abstract provided.

Beyond Drainage: Can Pleural Effusion Serve As A Natural Tamponade Against Tumor Hemorrhage? A Case Report And Mechanistic Hypothesis, Pratyush Kumar, Kumar Abhishek, Pankti Shah, Amelia Goslin, Archana Machavarapu, Catherine Joyce, Michael Waxman

MidAmerica Division GME Healthcare Symposium 2026

No abstract provided.

Implications Of Glp-1 Receptor Agonist Semaglutide For Hysterectomy Outcomes, Tess Branstetter, Megan Foster, Abbey Fritzel, Kimberly Swan, Alyssa Kozlowski, Jeffrey Durbin, Jordan Martin, Kari Nilsen

MidAmerica Division GME Healthcare Symposium 2026

No abstract provided.

Case Report: Spontaneous Gastric Intramural Hematoma With Intramural Dissection, Pedro De Castro, Rachel Steffes, John Surbeck, Anthony Melillo, Vince Narciso, Mohsin Soliman

MidAmerica Division GME Healthcare Symposium 2026

No abstract provided.

Turning Yellow On Rhythm Control: Dofetilide And The Unexpected Cholestatic Storm, Tejaswi Vadde, Mohammad Mahfouz, Prithvi Basu Roy, Subuhee Ahmed, Archana Machavarapu, Chelsea Curry

MidAmerica Division GME Healthcare Symposium 2026

No abstract provided.

Presentation And Application Of External Fixator Kickstand De-Rotational Bar Modification, Speros Gabriel, Grace Thiel, Cameron Sprong, Molly Black

MidAmerica Division GME Healthcare Symposium 2026

No abstract provided.