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Articles 1 - 30 of 1449

Full-Text Articles in Diseases

A Mixed Methods Study Of Inpatients’ Experiences, Priorities, And Health-Related Quality Of Life During High- Flow Nasal Cannula Therapy, Cintamani H. Ellsworth, Rebecca S. Bartlett Sep 2026

A Mixed Methods Study Of Inpatients’ Experiences, Priorities, And Health-Related Quality Of Life During High- Flow Nasal Cannula Therapy, Cintamani H. Ellsworth, Rebecca S. Bartlett

Journal of Patient-Centered Research and Reviews

Purpose: High-flow nasal cannula (HFNC) is an oxygen delivery method with numerous benefits for severely ill patients. There is a paucity of research focused on the perspectives of patients receiving HFNC oxygen therapy. This study aimed to engage with patients to gain a clearer understanding of their experiences, priorities, and health-related quality of life.

Methods: A cross-sectional, mixed methods study was completed with 10 adult inpatients who had received HFNC oxygen therapy during their hospital admission. Semi-structured interviews and the Patient Reported Outcomes Measurement Information System (PROMIS) Global Health Scale were used to identify participant perceptions of their physical and …


Metastatic Large Cell Neuroendocrine Carcinoma: A Rare Cause Of Hypopituitarism, Smriti Nair, Taskeen Ahmed, Jessica Watari Jul 2026

Metastatic Large Cell Neuroendocrine Carcinoma: A Rare Cause Of Hypopituitarism, Smriti Nair, Taskeen Ahmed, Jessica Watari

Division of Internal Medicine Faculty Papers & Presentations

Pituitary metastases from pulmonary large cell neuroendocrine carcinoma (LCNEC) are exceedingly rare but should be considered in patients presenting with arginine vasopressin deficiency and panhypopituitarism in the context of known or suspected metastatic lung cancer. Early recognition and prompt initiation of hormonal replacement therapy are essential to prevent life-threatening endocrine crises and to improve symptom burden. We describe a case of a 43-year-old male who presented with dyspnea, weight loss, and weakness who was found to have metastatic LCNEC involving the liver. Endocrine evaluation revealed central hypothyroidism, central adrenal insufficiency, and later arginine vasopressin deficiency manifested by polyuria and hypernatremia. …


Navigating Complex Esophageal Perforations: A Case-Specific Approach To Successful Outcomes, Harsimran Kalsi, Anushree Rai, Kobina Essilfie-Quaye, Neeka Akhavan, Yaseen Perbtani, Tony S. Brar Jun 2026

Navigating Complex Esophageal Perforations: A Case-Specific Approach To Successful Outcomes, Harsimran Kalsi, Anushree Rai, Kobina Essilfie-Quaye, Neeka Akhavan, Yaseen Perbtani, Tony S. Brar

HCA Healthcare Journal of Medicine

Esophageal perforation is a life-threatening condition requiring prompt diagnosis and effective management. While self-expanding metal stents (SEMS) are a first-line treatment, persistent leaks often necessitate adjunctive endoscopic interventions. A structured, multimodal approach is critical for optimizing outcomes and avoiding surgical intervention. A 44-year-old man developed an iatrogenic esophageal perforation following surgical leiomyoma enucleation. Initial treatment with overlapping fully covered self-expanding metal stents (FC-SEMS) failed to achieve closure, necessitating endoscopic suturing for defect reinforcement. Despite suturing, persistent leakage required placement of a larger-diameter FC-SEMS, secured with an endoscopic fixation system to prevent migration. Serial imaging confirmed successful defect closure, allowing the …


Hubungan Penggantian Imunosupresan Tidak Terencana Dengan Aktivitas Penyakit Lupus Eritematosus Sistemik: Studi Kohort Retrospektif Di Rsupn Dr. Cipto Mangunkusumo, Jakarta, Rosvitha Amanda, Sukamto Koesnoe, Alvina Widhani, Ikhwan Rinaldi, Adityo Susilo, Juferdy Kurniawan, Rudi Putranto, Birry Karim Jun 2026

Hubungan Penggantian Imunosupresan Tidak Terencana Dengan Aktivitas Penyakit Lupus Eritematosus Sistemik: Studi Kohort Retrospektif Di Rsupn Dr. Cipto Mangunkusumo, Jakarta, Rosvitha Amanda, Sukamto Koesnoe, Alvina Widhani, Ikhwan Rinaldi, Adityo Susilo, Juferdy Kurniawan, Rudi Putranto, Birry Karim

Jurnal Penyakit Dalam Indonesia

Introduction. Systemic lupus erythematosus (SLE) is a complex chronic autoimmune disease with diverse clinical manifestations. Treatment stabilization is crucial for optimal disease control, but the consistency of immunosuppressive therapy may be affected by non-ideal conditions, including drug unavailability or adverse effects. This study aimed to assess the association between unplanned immunosuppressant switching and increased disease activity in SLE patients.

Methods. A retrospective cohort study of SLE patients meeting the inclusion criteria, whose disease activity was evaluated using the MEX-SLEDAI score during immunosuppressant substitution. Participants were grouped into an exposed group undergoing unplanned immunosuppressant switching due to drug unavailability …


Comparison Of Ecg Features, Cardiac Biomarkers, And Clinical Outcomes In Three Waves Of Hospitalized Covid-19 Pneumonia Patients With Cardiovascular Events, Yuchen Han, Jahnavi Sunkara, Tshura S Ali, Harideep Samanapally, Vidyulata Salunkhe, Fnu Deepti, Emma C. Huang, Justin J. Huang, Maiying Kong, Jiapeng Huang May 2026

Comparison Of Ecg Features, Cardiac Biomarkers, And Clinical Outcomes In Three Waves Of Hospitalized Covid-19 Pneumonia Patients With Cardiovascular Events, Yuchen Han, Jahnavi Sunkara, Tshura S Ali, Harideep Samanapally, Vidyulata Salunkhe, Fnu Deepti, Emma C. Huang, Justin J. Huang, Maiying Kong, Jiapeng Huang

The University of Louisville Journal of Respiratory Infections

Background

Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is a rapidly evolving virus that can severely impact the cardiovascular system. With new variants, it is important to characterize wave-specific (defined by dominant circulating variants) clinical changes.

Methods

A multi-center retrospective cohort study of patients hospitalized with SARS-CoV-2 community acquired pneumonia at eight adult acute-care hospitals in the city of Louisville, KY was conducted. Patients hospitalized with Coronavirus Disease 2019 (COVID-19) community acquired pneumonia who experienced a cardiovascular event between March 2020 and July 2022 were included in this analysis. Variant assignment was based on temporal prevalence rather than genomic confirmation, and …


Optimizing Antibiotic Strategies With A Clinical Pathway Approach: Enhanced Initiation And De-Escalation In Community-Acquired Pneumonia, Ahmad Behzadpour Apr 2026

Optimizing Antibiotic Strategies With A Clinical Pathway Approach: Enhanced Initiation And De-Escalation In Community-Acquired Pneumonia, Ahmad Behzadpour

HCA Healthcare Journal of Medicine

Background

Community-acquired pneumonia (CAP) remains a leading cause of hospitalization, mortality, and health care expenditure worldwide. Inappropriate use of broad-spectrum antibiotics contributes to antimicrobial resistance, adverse drug events, and increased costs. Antibiotic stewardship and standardized clinical pathways are key strategies to improve prescribing practices.

Methods

This quality improvement (QI) initiative was conducted at a 240-bed tertiary care teaching hospital from January 2023 through January 2025. A CAP-specific digital clinical pathway was developed using Curbside Health® and integrated into the electronic health record (EHR), accessible through a structured order set to support real-time clinical decision-making. The intervention included provider education and …


Bilateral Intracranial Subdural Hematoma Following Epidural Anesthesia, Eric B. Cox, Adaeza Onuoha Apr 2026

Bilateral Intracranial Subdural Hematoma Following Epidural Anesthesia, Eric B. Cox, Adaeza Onuoha

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


From Hard Hat To Headache: Cryptococcal Empyema And Meningitis In A Newly Diagnosed Hiv-Positive Construction Worker, Sebastian Echegaray, Collin Vargas, Vy Ngo Apr 2026

From Hard Hat To Headache: Cryptococcal Empyema And Meningitis In A Newly Diagnosed Hiv-Positive Construction Worker, Sebastian Echegaray, Collin Vargas, Vy Ngo

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


Fatal Ochrobactrum Anthropi Bacteremia Following Intravenous Stem Cell Therapy In Immunocompetent Patient, Daler Kudratov, Wendy Martinez, Jonathan Barnett Apr 2026

Fatal Ochrobactrum Anthropi Bacteremia Following Intravenous Stem Cell Therapy In Immunocompetent Patient, Daler Kudratov, Wendy Martinez, Jonathan Barnett

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


Coexisting Systemic Lupus Erythematosus And Acquired Thrombotic Thrombocytopenic Purpura In A Clinically Stable Patient With Class V Lupus Nephritis, Anabel Al Abdallah, Nimmy Joy, Rodrigo Alfaro Apr 2026

Coexisting Systemic Lupus Erythematosus And Acquired Thrombotic Thrombocytopenic Purpura In A Clinically Stable Patient With Class V Lupus Nephritis, Anabel Al Abdallah, Nimmy Joy, Rodrigo Alfaro

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


A Case Of Secondary Hemophagocytic Lymphohistiocytosis, Nafis Deen, Sarita Thanedar, Aaron De La Cruz Apr 2026

A Case Of Secondary Hemophagocytic Lymphohistiocytosis, Nafis Deen, Sarita Thanedar, Aaron De La Cruz

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


Trends And Demographic Disparities In Septicemia-Associated Cardiac Arrest Mortality In The United States, 1999–2023, Muhammad Owais, Maham Mehfooz, Hamza Nazir, Preeti Advani, Roha Riaz, Khanij Arya, Javeria Nawaz, Syed Hadi Raza Rizvi, Murtaza Aslam, Usman Nazeer, Jairo Melo, Bravein Amalakuhan Apr 2026

Trends And Demographic Disparities In Septicemia-Associated Cardiac Arrest Mortality In The United States, 1999–2023, Muhammad Owais, Maham Mehfooz, Hamza Nazir, Preeti Advani, Roha Riaz, Khanij Arya, Javeria Nawaz, Syed Hadi Raza Rizvi, Murtaza Aslam, Usman Nazeer, Jairo Melo, Bravein Amalakuhan

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


Recurrent Ventricular Tachycardia In Young Hcm Patient With Icd, Michael Rollins, Garza, Laura Preece Apr 2026

Recurrent Ventricular Tachycardia In Young Hcm Patient With Icd, Michael Rollins, Garza, Laura Preece

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


Type 2 Diabetes Mellitus And Early Peg Tube Complications, Eric E. Romero Rodriguez, Adrian Reta, Angelo Manuel Piazza, Kuljot Bansi Apr 2026

Type 2 Diabetes Mellitus And Early Peg Tube Complications, Eric E. Romero Rodriguez, Adrian Reta, Angelo Manuel Piazza, Kuljot Bansi

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


Structural Degeneration Of The Neoaortic Valve Leading To Pseudoaneurysm And Neurologic Complications Post-Ross Procedure, Cassandra Millan, Sarita Thanedar, Chandra Kunavarapu Apr 2026

Structural Degeneration Of The Neoaortic Valve Leading To Pseudoaneurysm And Neurologic Complications Post-Ross Procedure, Cassandra Millan, Sarita Thanedar, Chandra Kunavarapu

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


The Future Of Right-Sided Endocarditis?: A Case Report Of Tricuspid Valve Endocarditis Treated With Angiovac And Review Of Current Literature, Saad Masud, Gongkai Liu, Hayyan Yousuf, Bravein Amalakuhan Apr 2026

The Future Of Right-Sided Endocarditis?: A Case Report Of Tricuspid Valve Endocarditis Treated With Angiovac And Review Of Current Literature, Saad Masud, Gongkai Liu, Hayyan Yousuf, Bravein Amalakuhan

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


Severe Gastritis Mimics Acute Coronary Syndrome With Elevated Cardiac Enzymes, Michael Rollins, Laura Preece, Micheline Tantchou Apr 2026

Severe Gastritis Mimics Acute Coronary Syndrome With Elevated Cardiac Enzymes, Michael Rollins, Laura Preece, Micheline Tantchou

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


Welch Allyn Panoptic Fundoscopic Training For Internal Medicine Residents, Vinh Ngo, Huy Vuong, Oscar Garcia Apr 2026

Welch Allyn Panoptic Fundoscopic Training For Internal Medicine Residents, Vinh Ngo, Huy Vuong, Oscar Garcia

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


Rare Clinical Presentation Of Primary Cutaneous Diffuse Large B-Cell Lymphoma (Pcdlbcl), Germinal Center B-Cell Subtype (Gcb), Confined To The Scalp, Anabel Al Abdallah, Angelo Piazza Ortiz, Joshua Rodriguez, Juan Herrada Apr 2026

Rare Clinical Presentation Of Primary Cutaneous Diffuse Large B-Cell Lymphoma (Pcdlbcl), Germinal Center B-Cell Subtype (Gcb), Confined To The Scalp, Anabel Al Abdallah, Angelo Piazza Ortiz, Joshua Rodriguez, Juan Herrada

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


A Rare Complication Of Leukemic Retinopathy Secondary To Chronic Myeloid Leukemia In Blast Phase, Waleed S. Malik, Vinh Ngo, Kuljot Bansi Apr 2026

A Rare Complication Of Leukemic Retinopathy Secondary To Chronic Myeloid Leukemia In Blast Phase, Waleed S. Malik, Vinh Ngo, Kuljot Bansi

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


Organ Function Over Genotype: A Clinical Lesson From Multiple Myeloma With Severe Systemic Al Amyloidosis, Anabel Al Abdallah, Aasia Khan Apr 2026

Organ Function Over Genotype: A Clinical Lesson From Multiple Myeloma With Severe Systemic Al Amyloidosis, Anabel Al Abdallah, Aasia Khan

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


Takotsubo With High Degree Av Block: A Case Report, Huy Vuong, Nimmy Joy, Kuljot Bansi Apr 2026

Takotsubo With High Degree Av Block: A Case Report, Huy Vuong, Nimmy Joy, Kuljot Bansi

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


Advanced Carcinoid Heart Disease: A Case Of Fatal Postoperative Shock, Gongkai Liu, Saad Masud, Sarita Thanedar Apr 2026

Advanced Carcinoid Heart Disease: A Case Of Fatal Postoperative Shock, Gongkai Liu, Saad Masud, Sarita Thanedar

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


High Procedural Success And Functional Improvement After Transcatheter Edge-To-Edge Repair: Insights From A Single-Center Registry, Gongkai Liu, Saad Masud, Taylor Triana, Jorge Alvarez, Daniel Donovan, Jose Fernando Triana Apr 2026

High Procedural Success And Functional Improvement After Transcatheter Edge-To-Edge Repair: Insights From A Single-Center Registry, Gongkai Liu, Saad Masud, Taylor Triana, Jorge Alvarez, Daniel Donovan, Jose Fernando Triana

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


The Unusual Suspects: A Rare Presentation Of Waterhouse-Friderichsen Syndrome, Nafis Deen, Nawsin Baset, Bravein Amalakuhan Apr 2026

The Unusual Suspects: A Rare Presentation Of Waterhouse-Friderichsen Syndrome, Nafis Deen, Nawsin Baset, Bravein Amalakuhan

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


An Unusual Brain Invader: A Case Of Adult Viral Meningitis, Gregory Williams, Jonathan Barnett Apr 2026

An Unusual Brain Invader: A Case Of Adult Viral Meningitis, Gregory Williams, Jonathan Barnett

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


Catheter Directed Thrombolysis And Aspiration Thrombectomy In Patients Treated For Pulmonary Embolisms: In-Hospital Outcomes, Amelia Mellor, Daniel Ortiz, Suzanne Perkins Apr 2026

Catheter Directed Thrombolysis And Aspiration Thrombectomy In Patients Treated For Pulmonary Embolisms: In-Hospital Outcomes, Amelia Mellor, Daniel Ortiz, Suzanne Perkins

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


Progressive Neuropathy With Normal Vitamin B12 Levels And Demyelinating Findings, Michael Rollins, Juan Rodriguez, Laura Preece Apr 2026

Progressive Neuropathy With Normal Vitamin B12 Levels And Demyelinating Findings, Michael Rollins, Juan Rodriguez, Laura Preece

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


An Unlikely Killer: Iatrogenic Botulism And Respiratory Paralysis As A Result Of Botched Botox Injection, Gregory Williams, Anabel Al Abdallah, Jonathan Barnett Apr 2026

An Unlikely Killer: Iatrogenic Botulism And Respiratory Paralysis As A Result Of Botched Botox Injection, Gregory Williams, Anabel Al Abdallah, Jonathan Barnett

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


Symptomatic Chiari 1 Malformation In A 35-Year-Old Female, Ignatius Mmodebelu, Jaime Natividad, Jonathan Carpenter, Juan Rodriguez Apr 2026

Symptomatic Chiari 1 Malformation In A 35-Year-Old Female, Ignatius Mmodebelu, Jaime Natividad, Jonathan Carpenter, Juan Rodriguez

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.