Analytical, Diagnostic and Therapeutic Techniques and Equipment Commons^™

Interaoperative Frozen Section Consultation: An Analysis Of Accuracy In A Teaching Hospital., Farrukh Aijaz, Suhail Muzaffar, Akbar Shah Hussainy, Shahid Pervez, Sheema H. Hasan, Hizbullah Sheikh

Department of Pathology and Laboratory Medicine

This Is a retrospective quality assurance study of all frozen sections done at The Aga Khan University Hospital during a six year period (1986 to 1991). There were 1,031 frozen sections out of a cumulative total of 42,985 surgical specimens (2.39%). Nine hundred and seventy-six (94.66%) were concordant. In 92(8.9%) fresh specimens were brought from other hospitals of Karachi, in 37 cases (3.58%) the diagnosis was deferred till the evaluation of permanent paraffin sections and 18 (1,74%) were discordant with 7 (0.67%) false positive and 11(1,06%) false negative. Among the discordant cases, 9 were attributed to misinterpretation, 7 due to …

Update - September 1993, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- Abortion in Context: Individual, Family, and Community
-- Abortion Guidelines, Seventh-day Adventist Church, October 12, 1992
-- Holding Values in Tension: The 1992 Abortion Guidelines
-- Adventist Abortion Guidelines: A Clinical Ethicist's Perspective

[ Behind the Scenes: Development of the Abortion Guidelines ]

Evaluation Of Trismus Associated With Mandibular Fractures As It Relates To The Need For Direct Laryngoscopy And Intubation : A Prospective Study, Stephen T. Goei

Loma Linda University Electronic Theses, Dissertations & Projects

Trismus associated with mandibular fractures is thought to increase the risks of general anesthesia. Nasotracheal intubation is necessary since the dental arches will be occluded at the end of the procedure. To establish an airway, an awake nasal intubation or fiberoptic endoscopy is required if direct laryngoscopy cannot be performed due to trismus. A prospective analysis of fifty-one patients with various types of mandibular fractures indicated that trismus was for the most part due to two factors, pain induced guarding and infection. In this series, direct laryngoscopy was easily performed after induction and paralyzation in cases without infection. Direct laryngoscopy …

Tracking Plasma Lactate Concentration In Vivo With A Catheter-Tip L-Lactate Sensor, Brett T. Weinzapfel, Mark D. Ball, Lee R. Waite, Nacer E. Abrouk, Shun P. Lim

Mathematical Sciences Technical Reports (MSTR)

To circumvent the problems of repeated blood sampling for in vitro analysis, a catheter-tip L-lactate sensor has been developed. The sensor was tested in anesthetized pigs (n=6). The sensor in vivo tracked the lactate concentration non-linearly, seeming to obey Michaelis-Menten kinetics. Calibration time was short, typically 1.5 min per lactate standard. Furthermore, time drift was small, typically -1.3% to -3.3% per hour of in vivo use.

Update - September 1992, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- Euthanasia in the Netherlands - Excepts from an interview with Rob Willem Treep

[ Kevorkian and Assisted Suicide ]
-- Thoughts Provoked by Dr. Kevorkian's Suicide Machine
-- Because Laws Against Euthanasia Send a Broader Signal, Experiments Must be Careful
-- Act of Murder or Active Compassion?

Book Review, Darold T. Barnum

RISK: Health, Safety & Environment (1990-2002)

Review of the following: HELENA CHMURA KRAEMER, EVALUATING MEDICAL TESTS: OBJECTIVE AND QUANTITATIVE GUIDELINES. (Sage Publications 1992). [295 pp.] Foreword A. John Rush, M.D. Acknowledgments, index, list of statistical notations, preface, references, and about the author. ISBN 0- 8039-4611-2 (cloth); 0-8039-4612-0 (paper). [Cloth $45.00, paper $22.50. 2455 Teller Road, Newbury Park CA 91320.1

The Mmpi-2 Clinical Scales And Clinical Diagnosis: Differentiating Between Schizophrenic And Bipolar-Manic Disorders, Laura M. Volkmann

Graduate Theses

The validity of the Minnesota Multiphasic Personality Inventory (MMPI-2) clinical scales in differentiating schizophrenia and bipolar-manic disorders was evaluated in terms of MMPI-2 congruence with psychiatric hospital treatment team diagnoses. From a pool of 286 MMPI-2 profiles, valid profiles were obtained on 5 schizophrenia (paranoid type) inpatients and 5 bipolar-manic disordered psychiatric inpatients and were assessed by using each of four MMPI profile classification methods. Overall, the rate of agreement between treatment team diagnosis and the MMPI profile classification methods for both the schizophrenia (paranoid type) and bipolar-manic disordered groups was inconclusive. The results suggest that the MMPI-2 is of …

Update - May 1992, Loma Linda University Center For Christian Bioethics

Update

In this issue:

[ Faith, Medicine, and Religious Liberty - Part 2, Christian Science ]
-- Spiritual Healing for Children
-- Religious Liberty, Spiritual Healing, and the Health Care of Children
-- Spiritual Healing, Laws, and Constitutional Free Exercise of Religious Rights
-- Baby Theresa: Parental Choice Must Reign in the Case of Brain-Absent Newborns
-- Anencephalic Infants as Organ Donors: Do We Follow Rules or Emotions?

Legal Issues Surrounding Preemployment Physical Examinations In The Coal Industry, Daniel L. Stickler, Albert F. Sebok

West Virginia Law Review

No abstract provided.

Update - February 1992, Loma Linda University Center For Christian Bioethics

Update

In this issue:

[ Faith, Medicine, and Religious Liberty - Part 1, Jehovah's Witnesses ]
-- Blood Transfusions: A Patient's Right to Refuse
-- Jehovah's Witnesses and Blood Transfusion
-- Blood Transfusions: A Patient's Right to Refuse
-- A Patient's Right to Refuse Blood Transfusions: The Legal Rights of Privacy, Autonomy, and Free Exercise of Religion

-- [ Second National Conference on Health Care for the Elderly Co-sponsored by the Center for Christian Bioethics and Multidisciplinary Geriatric Council - March 1 & 2 ]

Improved Recovery Of A Radlolabeled Peptide With An Albumin-Treated Reversed-Phase Hplc Column, David S. Hage, Robert L. Taylor, Pai C. Kao

David Hage Publications

Reversed-phase high-performance liquid chromatography (RP-HPLC) is an important tool in the purification of radiolabeled peptides and proteins for immunoassay. However, for some proteins and peptides it is difficult to achieve reproducible behavior in RP-HPLC because of the low recovery of these compounds. Factors that can be varied to improve recovery include the strength or pH of the mobile phase, the chain length and spacing of groups on the reversed-phase support, and the flow rate or steepness of the elution gradient (1-5). ... In summary, we obtained better recovery and more reproducible chromatographic behavior for labeled 1-34 PTHrP with an albumin-pretreated …

Intact Parathyroid Hormone: Performance And Clinical Utility Of An Automated Assay Based On High-Performance Immunoaffinity Chromatography And Chemiluminescence Detection, David S. Hage, Bob Taylor, Pai C. Kao

David Hage Publications

The performance and clinical utility of an automated assay of intact parathyroid hormone (parathyrin, PTH) are evaluated. The method is based on the extraction of PTH from plasma by an HPLC column containing immobilized anti-(44-68 PTH) antibodies. The PTH retained is detected with a postcolumn reactor and use of anti-(1--34 PTH) chemiluminescent-labeled antibodies. The total cycle time of the assay is 6.5 mm per injection after a 1-h incubation.The lower limit of detection for PTH in a 66-pL plasma sample was 0.5 pmol/L based on peak heights and 0.2 pmol/L based on peak areas. Mean analytical recovery for PTH added …

Update - December 1991, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- The Physician as an Agent of God: An Idea Whose Time Has Come

-- [ Medical Futility: A Value-Dependent Concept ]

An In Vitro Evaluation Of Commercially Available Disposable Prophylaxis Angles, Caren M. Barnes, Lisa S. Fleming, Carl M. Russell

College of Dentistry: Faculty Publications

Although a number of manufacturers are marketing disposable prophylaxis angles, no literature exists regarding the mechanical efficacy and efficiency of these products. It was the purpose of this in vitro evaluation to compare and evaluate five brands of commercially available disposable prophylaxis angles for vibration, noise, heat rise, and torque. Random samples of each brand of disposable prophylaxis angle were utilized. Vibration was measured with a height gauge and running motor; noise was measured with a sound meter and heat rise was measured from 68°F on the head and body of the disposable prophylaxis angles, and torque required to destroy …

An In Vivo Comparison Of Commercially Available Disposable Prophylaxis Angles, Lisa S. Fleming, Caren M. Barnes, Carl M. Russell

College of Dentistry: Faculty Publications

A wide variety of disposable infection control products is being marketed including disposable prophylaxis angles. It was the purpose of this in vivo investigation to evaluate the clinical efficacy of five different brands of commercially available disposable prophylaxis angles. Utilizing a splitmouth design. 11 dental hygienists evaluated disposable prophylaxis angles while completing a routine oral prophylaxis. Fifty samples each of Brahler. Ash/Dentsply, Denticator. and Young Dental angles were compared to a control angle (Teledyne Getz). A questionnaire was completed by each operator following patient treatment (a total of 161 patients was treated). The questionnaire asked questions in which the four …

The Management Of Aerosols With Airpolishing Delivery Systems, Caren M. Barnes

College of Dentistry: Faculty Publications

In summary. aerosol production is inherent with airpolishers. as well as other dental equipment such as handpieces, ultrasonic scalers, and air/water syringes. By practicing prudent infection control techniques and utilizing proper operating techniques, the clinician can continue to enjoy the time-efficient and efficacious benefits of airpolishers, while ensuring a maximum protection from aerosols for the patient and the operator.

The Fracture Strength Of Ceramic Brackets : An Update And Comparison, Christian P. Manley

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study was to compare the fracture strength of ceramic brackets which are currently on the market with ceramic brackets tested in a previous study at Loma Linda. Fracture strengths of standard edgewise ceramic brackets vs. pre-torqued ceramic brackets and bicuspid ceramic brackets vs. central incisor ceramic brackets were also compared.

A total of 160 Polycrystalline brackets, 8 categories in groups if 20, were tested for fracture strength. Each bracket was tested using the same testing model that was used in the previous study at Loma Linda. The brackets were tested by torquing a wire within the …

The Accuracy Of Sonographic Imaging (Dolphintm Digigraph) And Standard Lateral Cephalometric Radiographs : A Comparative Study, Michael D. Teichman

Loma Linda University Electronic Theses, Dissertations & Projects

Radiation due to x-ray exposure is a concern, and the development of the Dolphin™ DigiGraph represents an attempt to limit this exposure. The purpose of this paper was to compare measurements (using Ricketts analysis) obtained from conventional radiographic cephalometric tracings with those obtained by computerized digitizing with the DigiGraph. Forty-six patients from the Loma Linda University School of Dentistry graduate orthodontic clinic were digitized, and the results were compared to the x-ray tracings of these patients. The results showed that seven of the twenty-one variables examined exhibited a statistical similarity between the two methods (DigiGraph and x-ray tracing). An examination …

The Use Of Corrected Occlusal X-Ray For Determination Of Ald : A Comparative Study, Merlin D. Ekvall

Loma Linda University Electronic Theses, Dissertations & Projects

In this study arch length discrepancy or ALD was studied in 50 untreated patients. The measurements obtained from Hilgers' corrected occlusal x-ray using his Occlusal Paralleling Instrument or O.P.I, were compared with those derived by four conventional methods, - "Eye balling," digital caliper determination, conventional mandibular x-ray, and the Rocky Mountain Data Systems computer analysis (31 cases). When using the OPI, results give a higher negative ALD as it takes into consideration the space required to level a curve of Spee.

Measurements were made by the author and 3 faculty members using the above methods. Statistical analysis of the means …

The Effects Of Suxamethonium And Pancuronium On The Haemodynamic Response To Endotracheal Intubation, F A. Khan, R S. Kamal

Department of Anaesthesia

The pharmacological effects of suxamethonium and pancuronium on the cardiovascular system may vary and therefore alter the haemodynamic response to intubation. The arterial blood pressure, the heart rate and the rate pressure product were measured as parameters of haemodynamic change in forty adult ASA. I and II patients undergoing laryngoscopy and endotracheal intubation in a randomised controlled study. The patients were induced with either thiopentone/suxamethonium (Group A) or thiopentone/pancuronium (Group B). There was no significant difference between the groups on comparison of systolic and diastolic blood pressure changes. Pancuronium, however, caused a significantly higher rise in the heart rate after …

Patterns Of Hydroxyproline Excretion In Ovariectomized And Estrogen Treated Rats, Gregg Horras

Presidential Scholars Theses (1990 – 2006)

If nuclear binding sites for estrogens exist in bone cells, then the origin of estrogen-deficiency-induced osteopenia may be at the level of bone matrix protein synthesis. Since collagen is the most abundant protein in the bone matrix, and since hydroxyproline is an imino acid nearly exclusive to collagen, a monitoring of the metabolism of hydroxyproline in ovariectomized and estrogen treated rats may provide insight into the patterns of estrogen-deficiency-induced osteopenia. The purpose of our study was to test the hypothesis that ovariectomy will increase urinary hydroxyproline excretion in the rat and that this increase will be reversed by estrogen treatment …

Update - December 1990, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- The euthanasia debate in the Netherlands: Biolegal, bioethical and biotheological considerations

[ In Vito Fertilization and Divorce ]
-- What Can We Learn?
-- A Legal Perspective
-- Some Thoughts Regarding Frozen Embryos and Devorce

Book Reviews, John M. Gleason

RISK: Health, Safety & Environment (1990-2002)

Reviews of the books: Mark A. Rothstein, Medical Screening and the Employee Health Cost Crisis (BNA Books 1989). Foreword Edward L. Baker, MD, MPH. 296 pp. Notes, figures, tables, glossary of legal terms, glossary of medical and health care terms, table of cases and index. LC 89-977; ISBN 0-87179-628-7.

Robert Decresce, Mark Lifshitz, Adrianne Mazura, & Joseph Tilson, Drug Testing In The Workplace (ASCP Press and BNA Books 1989). Forewords by Edward Miller, JD and George Lundberg, MD. 278 pp. Notes, figures, tables, table of cases and index. LC 88-39191; ISBN 0-89189-260-5 (ASCP), 0-87179-588-4 (BNA). Both of these books deal …

Quantitative Respirator Fit Testing: Probed Facepiece Versus Probed Cartridge, Sonya Melissa Seward

Community & Environmental Health Theses & Dissertations

This study was performed to determine if there is a quantifiable difference between quantitative fit testing using a probed facepiece and a probed cartridge. Four subjects were tested on four different respirators. The respirators used were MSA & 3M full and half face respirator. Each subject performed each method five times per respirator. The results indicated no correlation between the two fit testing methods overall. However, a moderate correlation was found between the MSA respirators and the two methods. This study found many variables which influence fit testing. These include the type of respirator used (brand and facepiece), the probe …

The Long Term Stability Of The Dental Arches Following Rapid Palatal Expansion, Robert C. Stockdale

Loma Linda University Electronic Theses, Dissertations & Projects

The rapid palatal expander is an appliance which has been used to laterally expand the maxillary dental arch, with subsequent mandibular dental arch expansion.

The purpose of this study was to evaluate and quantify long term post treatment changes in the length and width of both dental arches following rapid palatal expansion.

Plaster models from eleven patients treated with rapid palatal expansion were obtained seven or more years after treatment. The dental arches were intact anterior to the first molars and no retreatment had taken place.

Maxillary and mandibular canine, premolar and molar arch width, arch length, arch circumference, and …

Evaluation Of Headgear Safety : A Comparative Study, William J. Pritchard

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study was to determine the relative safety of headgear safety straps. Samples from five different safety headgear straps simulated orthopedic and orthodontic use and data were collected from a series of pulls on an Instron machine. The straps were compared by the distance the face bow traveled before the safety mechanism released, the force built into the face bow at safety release and the force required to remove the inner bow out of the molar tube. The conclusions are as follows: (1) the distance a face bow can travel from the molar tube and still be …

A Modified Nance Unilateral Molar Distalizer, Tracy J. Reiner

Loma Linda University Electronic Theses, Dissertations & Projects

This clinical study evaluated a modified Nance appliance designed by the author to distalize molars unilaterally for Class II correction. This fixed appliance did not rely upon extraoral traction or intraoral elastics. Twelve unilateral Class II patients aged 13 to 17 were treated nonextraction with the appliance. Pretreatment and posttreatment photographs were taken of the palatal soft tissue and did not reveal any untoward changes as a result of the Nance acrylic button. All molars were corrected to an Angle's Class I relationship. Molar correction was evaluated visually and molar distalization was measured using an acrylic jig fitted to the …

Update - May 1990, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- James Walters wins NEH Grant
-- Fraud in Modern Medicine
-- Roy Branson serves as guest professor of medical ethics
-- Cambridge publishes Michael Pearson's study of Adventist ethics

[ RU486: Blessing or Curse? ]
-- Medical Aspects of RU486
-- The Curse of RU486: The Death Pill
-- RU486: A Very Mixed Blessing

-- Robert Wirth sparks aging project

Update - December 1989, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- Australia's Herbert Clifford will lecture at Loma Linda on February 24
-- Claremont Conference endorses "The Right to Choose Death"
-- Michael and Helen Pearson arrive from England
-- Contributors receive monthly audio cassettes

[ Nancy Cruzan and the Courts ]
-- The Persistent Vegetative State
-- Nancy Cruzan is Already Dead
-- Nancy Cruzan is Not a Vegetable
-- My Family's Anguish

-- The Right to Choose Death

Update - June 1989, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- Etienne-Emile Baulieu discusses RU486
-- Walters edits War No More?

[ Abortion: Ethical Issues ]
-- Excerpts of papers presented at the "Abortion: Ethical Issues and Options" international conference

-- Elder, Guy, Provonsha and Winslow assess AIDS at A.P.C.