Medicine and Health Sciences Commons^™

Gautama Buddha: Illustration Of A Patient’S Vision, Haryashpal Bhullar

HCA Healthcare Journal of Medicine

As a psychiatrist in training, I often have the privilege to connect with the unique thoughts and visions patients may be experiencing. The descriptions shared by one patient during my early psychiatry inpatient rotations stuck with me and eventually inspired me to pursue a residency in the field. While interviewing, she expressed a deep spirituality and often finding solace in the mindfulness teachings of Gautama Buddha whenever she was distressed. She would strengthen this coping mechanism by contemplating him sitting and meditating deeply, within a naturalistic setting, however struggled in describing exactly what she was imagining. I further gathered this …

A Literature Review: An Analysis Of The Widespread Effects Of Solitary Confinement/Social Isolation On Mental Illness And Mortality, Taneasha Muonio

Theses and Graduate Projects

Solitary confinement or isolation is widespread globally and has been used as a form of punishment, reform, reflection, and cleansing throughout time. The devastating impacts of not having social interactions for extended periods of time have been documented and noted.1 These impacts include severe mental health disorders such as schizophrenia, bipolar disorder, anxiety, depression, post-traumatic stress disorder (PTSD), suicide, motor disturbances, biological changes, and increased mortality.1-3 The analysis of how the United States became the country with the largest prison system and mentally ill population is addressed in this thesis including understanding how the prison-industrial complex was built. Understanding how …

The Effectiveness Of Heart Rate Variability Biofeedback In Conjunction With Traditional Treatment For Thoracic Outlet Syndrome In A 25-Year-Old Female: A Case Report, Sepehr Rezaei

San Marcos, Summer 2020

Introduction: Thoracic outlet syndrome (TOS) is a complex condition that causes pain, tingling sensation, hypesthesia, muscle atrophy, weakness, and edematous changes in the upper quadrant (UQ) and down upper extremity (UE). ^3,7,8,16,17 TOS is due to compression of neurovascular bundles in the interscalene triangle, costoclavicular space, and under pectoralis minor and caused by trauma, congenital malformations such as a cervical rib, and abnormal/poor postures from muscle imbalances.^3,7,8,16,17 Interventions for TOS can consist of correcting posture by addressing muscle imbalance, decreasing tone and muscle tightness and rib mobilization, and in rare cases, rib resection. ^{3,7,8,13,16,17} However, there is limited research …

Tricyclic Antidepressant Use And Risk Of Fractures: A Meta-Analysis Of Cohort Studies Through The Use Of Both Frequentist And Bayesian Approaches, Qing Wu, Yingke Xu, Yueyang Bao, Jovan Alvarez, Mikee Lianne Gonzales

School of Medicine Faculty Research

Background: Research findings regarding the association between tricyclic antidepressant (TCA) treatment and the risk of fracture are not consistent; we aimed to assess whether people who take TCAs are at an increased fracture risk. Methods: Relevant studies published through June 2020 were identified through database searches of MEDLINE, EMBASE, Scopus, PsycINFO, ISI Web of Science, WorldCat Dissertations and Theses from each database’s inception, as well as through manual searches of relevant reference lists. Two researchers independently performed literature searches, study selection, data abstraction and study appraisal by using a standardized protocol. Frequentist and Bayesian hierarchical random-effects models were used for …

Bipolar Disorder, Heather Guthrie

Nursing Student Class Projects (Formerly MSN)

Bipolar disorder is a mental disorder that causes severe swings in mood, energy, activity, concentration, and activities of daily living. These mood swings range from extremely euphoric, irritable, or animated behavior (manic) to despondent, apathetic, or dejected periods (depressive). This phenomenon was why this disorder was known as manic-depressive or manic depression. The need to understand the multiple factors regarding the disease process of this disorder, and the importance of treatment is vital for the safety and health of people across the world inflicted by bipolar disorder. Education is the key to how this disorder affects the entire trajectory of …

Depression In Primary Care: With A Focus On First-Line Medications, Michael Danielewicz, Md

Department of Family & Community Medicine Presentations and Grand Rounds

This Lecture Will Cover:

• An overview of selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), bupropion and mirtazapine
• Appropriate selection and dose adjustments of first-line agents for depressive disorders in a primary care setting
• Monitoring and tapering first-line antidepressants
• Special considerations in treatment
• Future directions for antidepressant treatment

The Long-Term Multidimensional Impact Of Persistent Multisite Pain On Physical And Psychological Disability, And Mortality In Community-Dwelling Older Adults, Saurja Thapa

Graduate Doctoral Dissertations

Persistent multisite pain is highly prevalent, affecting 25-43% of community-dwelling older adults. Although existing evidence suggests that persistent multisite pain is associated with physical and psychological disability, studies use a cross-sectional assessment approach that overlooks pain duration or persistence. This study aimed to estimate the persistence of multisite pain and the proportion of incident multisite pain and examine the association between persistent multisite pain and physical (ADL and IADL) and psychological disability (depression and anxiety) at 18 months and six years. Also, the association between baseline persistent multisite pain and mortality was assessed.

Secondary data analysis of the MOBILIZE Boston …

The Relationship Between Sleep Duration And Mood In Adolescents: A Systematic Review And Meta-Analysis, Michelle A. Short, Stephen A. Booth, Omar Omar, Linda Ostlundh, Teresa Arora

All Works

© 2020 Elsevier Ltd Insufficient sleep has been argued to result in deleterious changes to mood in adolescents and offers promise as a modifiable risk factor. A systematic review of the literature regarding sleep duration and mood in adolescents was conducted using the academic databases PsycINFO, PubMed, Medline, Scopus, and EMBASE to identify relevant literature. Seventy-four studies, including 361,505 adolescents were sourced out of the 1534 references identified, 73 of which were appropriate for meta-analysis. Pooled results indicated that less sleep was associated with a 55% increase in the likelihood of mood deficits. Positive mood showed the largest relationship with …

Psychedelics: A Window To Mental Illness; Psilocybin And Depression, Kiomary Rivera Quintana

College of Pharmacy Student Research

No abstract provided.

Association Of Neighborhood Disorder And Minority Stress With Depression Among Young Gay And Bisexual Males In Denver And Chicago, Liesl Gonzales, Douglas Bruce

DePaul Discoveries

Excess risk for poor mental health outcomes has been found within sexual minority populations. This study aimed to examine factors that may contribute to depression rates within two populations of YMSM in Denver and Chicago. 100 HIV-positive and 100 HIV-negative YMSM completed a survey regarding demographic information, minority stress (such as same-sex stigma), and perceived neighborhood disorder. Chicago participants reported higher rates of neighborhood disorder, history of incarceration, and being kicked out of a parent’s house, variables predicted to be positively correlated with depression. Surprisingly, it was found that YMSM in Denver were significantly more likely to have depressive symptoms …

Perceived Risk And Protection From Infection And Depressive Symptoms Among Healthcare Workers In Mainland China And Hong Kong During Covid-19, Simon Ching Lam, Teresa Arora, Ian Grey, Lorna Kwai Ping Suen, Emma Yun Zhi Huang, Daofan Li, Kin Bong Hubert Lam

All Works

© Copyright © 2020 Lam, Arora, Grey, Suen, Huang, Li and Lam. Psychological health among healthcare workers (HCWs) has become a major concern since the COVID-19 outbreak. HCWs perceived risks of contracting COVID-19, in relation to depression were investigated. It was hypothesized that perceived high risk of contracting COVID-19 (close contact with cases, inadequate provision of personal protective equipment, insufficient infection control training, and presence of symptoms) would be significant predictors of depression. Our cross-sectional survey was completed by HCWs across three regions (Hubei, Guangdong, Hong Kong) between March 9 to April 9 2020 using convenience sampling. Depression was assessed …

Promising Swellable Floating Bupropion Tablets: Formulation, In Vitro/In Vivo Evaluation And Comparative Pharmacokinetic Study In Human Volunteers, Mahmoud Teaima, Magdi M.A. Hamid, Nabil A. Shoman, Bhaskara R. Jasti, Mohamed A. El-Nabarawi

Pacific Faculty Work

Purpose: Bupropion is an antidepressant drug that facilitates weight loss. It is a highly water-soluble drug that needs multiple dosing, so it is considered a potential candidate for oral controlled-release dosage form. The aim of this research was to formulate and evaluate satiety-inducing swellable floating bupropion tablets by direct compression targeting depression associated with eating disorders. Various combinations of natural and semi-synthetic hydrogels were selected to achieve maximum swelling and remaining buoyant in the stomach. This synergistically enhances weight loss by increasing satiety. Methods: An I-optimal mixture design was conducted to establish the optimal quantitative composition of tablets. Friability, floating …

The Network Structure Of Posttraumatic Stress Disorder Among Filipina Migrant Domestic Workers: Comorbidity With Depression, Melissa R. Garabiles, Chao K. Lao, Brian J. Hall

Psychology Department Faculty Publications

Background

Labour migrants are exposed to potentially traumatic events throughout the migration cycle, making them susceptible to developing mental disorders. Posttraumatic stress disorder (PTSD) is often comorbid with depression. Comorbidity worsens the course of illness, prognosis, treatment response, and increases suicidal risk. Using network analysis, this study examined the structure of PTSD and depression in a sample of migrant domestic workers, an especially vulnerable community of labour migrants. This study sought to derive the central or most important symptoms, strongest edges or relationships among symptoms, and bridge symptoms between PTSD and depression.

Methods

Data were obtained from 1,375 Filipina domestic …

Depression: The Cause, The Signs, The Stigma, Elisabeth Sanderson

Nursing Student Class Projects (Formerly MSN)

Depression is a common phenomenon. According to World Health Organization (2020) there are over 264 million people suffering from depression globally. Takahashi (2019) states that major depressive disorder is the most common mood disorder and additionally notes that it is the leading cause of disability not just in the United States but in the world. From a pathophysiological perspective depression has multiple possible causes. This paper seeks to look at depression as a relevant health care concern and to describe accepted theories on the pathophysiology of depression as well as discussing key signs and symptoms of the disorder. It seeks …

Psychedelics And Mental Health, Angelica Milla

College of Pharmacy Student Research

No abstract provided.

Factors Affecting Sleep Quality In Acute Coronary Syndrome Survivors, Pattaranan Susuthi, Doungrut Wattanakitkrileart, Kanaungnit Pongthavornkamol, Chatkanok Dumavibhat

Chulalongkorn Medical Journal

No abstract provided.

Effect Of Social Skills Training Program On Social Functioning In Patients With Major Depressive Disorder In Outpatient Psychiatric Department, King Chulalongkorn Memorial Hospital, Vanussanun Jannim, Peeraphon Lueboonthavatchai

Chulalongkorn Medical Journal

No abstract provided.

Wellness And Coping Of Residents In A Skilled Nursing Facility, Christine M. Larson

Doctoral Dissertations and Projects

Depression is common among older adults in long-term care (LTC) facilities. As many as 50%-80% of residents will experience depressive symptoms or have a diagnosis of depression. Depression increases the risk of poor health-related outcomes in older adults. A review of the literature suggests that early intervention using movement-based techniques decreases the risk for depression and improves depressive symptoms. This scholarly project aimed to reduce the risk of depression of residents in an LTC located in a suburban area in Midwestern United States. The LTC facility and a Doctor of Nursing Practice (DNP) student implemented the Chair One Fitness program …

Association Between Urinary Enterolignans As A Marker For Gut Microbiome Diversity And Depression In Nhanes, Marie Knoll

Theses and Dissertations

Depression is a chronic disease which inflicts functional and emotional impairment that has been a growing issue in the United States (US). Depression is the most prevalent mental disorder in the US and is the leading cause of disability in the world. By 2030, It is projected that major depressive disorder will be the second largest contributor to global burden of disease. Causes of depression are still largely unknown and treatments are often expensive, time consuming, and only available to certain populations. Treatment often requires a combination of medicines and therapy to be effective. In recent years, the gut microbiome …

The Association Of Comt Genotype With Buproprion Treatment Response In The Treatment Of Major Depressive Disorder., Jay Fawver Md, Mindy Flanagan, Thomas Smith, Michelle Drouin, Michael Mirro Md

Health Services and Informatics Research

BACKGROUND: Pharmacodynamics and pharmacogenetics are being explored in pharmacological treatment response for major depressive disorder (MDD). Interactions between genotype and treatment response may be dose dependent. In this study, we examined whether MDD patients with Met/Met, Met/Val, and Val/Val COMT genotypes differed in their response to bupropion in terms of depression scores.

METHODS: This study utilized a convenience sample of 241 adult outpatients (≥18 years) who met DSM-5 criteria for MDD and had visits at a Midwest psychopharmacology clinic between February 2016 and January 2017. Exclusion criteria included various comorbid medical, neurological, and psychiatric conditions and current use of benzodiazepines …

The Correlation Between Transforming Growth Factor-Beta (Tgf- Β) Serum Level And Beck Depression Inventory (Bdi) Score In Colorectal Cancer Patients At Rsmh Palembang, Muhammad Ali Apriansyah, Mediarty Syahrir, Muhammad Rosyidi Kgs, Ahmad Faisyar

Jurnal Penyakit Dalam Indonesia

Introduction. Depression not only increase the mortality rate, but also can interfere the quality of life of colorectal cancer patients during treatment. Low levels of systemic inflammation may contribute to the development of depression. The inflammatory process can be seen by measuring serum transforming growth factor-β (TGF-β) levels and depressive symptoms using the beck depression inventory (BDI) score. This study aimed to determine the correlation between TGF-β serum levels with depression in colorectal cancer patients. Methods. Analytical observational research with cross sectional design was conducted among colorectal cancer patients who underwent chemotherapy with a BDI score ≥10 (depression) in the …

Covid-19, Anxiety, And Depression: Evidence From The U.S. Household Pulse Survey, Xiaoyan Zhang

Population Health Research Brief Series

A large share of U.S. adults report feelings of anxiety and depression during COVID-19. The interactive figure allows you to explore demographic differences in reports of depression and anxiety among U.S. adults during COVID-19.

Association Between Self-Reported Dyspnea And Depressive Symptoms In New Mexico Uranium Workers, Shiva Sharma

Biomedical Sciences ETDs

BACKGROUND: Uranium workers risk experiencing dyspnea, a lung disease symptom. Previous studies found associations between dyspnea and depressive symptoms in lung disease, but this requires further study in occupational cohorts.

METHODS: This study evaluated the association between dyspnea and depressive symptoms in former uranium workers screened by New Mexico Radiation Exposure Screening & Education Program. Dyspnea and depressive symptoms were evaluated through questionnaires, Modified Medical Research Council Dyspnea Scale and a modified Patient Health Questionnaire-2, respectively. Logistic regression models were applied to cross-sectional analyses. Generalized linear models were applied to longitudinal analyses.

RESULTS: Cross-sectional analyses demonstrated higher dyspnea scores were …

The Comfort Level Of High School Athletic Trainers When Dealing With Mental Health Conditions, Kassidy Esser, Erika Smith-Goodwin, Jennifer Walker

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Please enjoy Volume 6, Issue 1 of the JSMAHS. In this issue, you will find Professional, Graduate, and Undergraduate research abstracts, and case reports.

Thank you for viewing this 6^th Annual OATA Special Edition.

Diffusion Dispersion Imaging: Mapping Oscillating Gradient Spin-Echo Frequency Dependence In The Human Brain., Aidin Arbabi, Jason Kai, Ali R Khan, Corey A Baron

Brain and Mind Institute Researchers' Publications

PURPOSE: Oscillating gradient spin-echo (OGSE) diffusion MRI provides information about the microstructure of biological tissues by means of the frequency dependence of the apparent diffusion coefficient (ADC). ADC dependence on OGSE frequency has been explored in numerous rodent studies, but applications in the human brain have been limited and have suffered from low contrast between different frequencies, long scan times, and a limited exploration of the nature of the ADC dependence on frequency.

THEORY AND METHODS: Multiple frequency OGSE acquisitions were acquired in healthy subjects at 7T to explore the power-law frequency dependence of ADC, the "diffusion dispersion." Furthermore, a …

Major Depression, Treatment Receipt, And Treatment Sources Among Non-Metropolitan And Metropolitan Adults, Tyrone F. Borders

Rural & Underserved Health Research Center Publications

Overview of Key Findings

• 7.8% of non-metropolitan (weighted number of persons=2,755,020) and 7.1% of metropolitan (weighted number of persons=14,868,655) adults had past year major depression.
• Treatment receipt (seeing a health professional or using prescription medication for depressive feelings) was similar among non-metropolitan (68.0%) and metropolitan (64.6%) adults.
• A closer examination of the type and source of treatment revealed the following:

• Rates of seeing a health professional were similar among non-metropolitan (60.8%) and metropolitan (58.4%) adults, but rates of using prescription medication for depressive feelings were higher among non-metropolitan (58.2%) than metropolitan (48.6%) adults.
• Rates of visiting a general practice/family doctor …

Initial Evaluation Of A Wellness Game, Bing Parkinson, Bruce St. Amour

Capital Division GME Virtual Research Day 2020

Physician wellness has recently been a topic of significant national interest.^1-8 The term “wellness” has many definitions, and was best defined by Around et al. ¹ as “one’s personal recipe for thriving and not just surviving.” Wellness refers to interconnected dimensions of physical, mental, and social well-being that extend beyond the absence of illness. Wellness has traditionally been measured in the negative sense by assessing rates of burnout, emotional exhaustion, and depersonalization. It is known that physician burnout is at its highest point during residency^{1, 4, 5} and burnout is linked to many negative outcomes including: substance abuse …

Scope Of Attention Variation As A Function Of Anxiety And Depression, Kathleen Anne O'Donnell

Electronic Theses, Projects, and Dissertations

As a social species, correct emotional perception is so vital, that the human brain has evolved a mechanism to control attentional choices by exerting a narrowed field of perception during danger, called the scope of attention (SoA). The SoA determines what information will be focused on or ignored by blocking the perception of non-relevant items and increasing selective focus on danger; even if danger is merely a sad-face. The emotional items blocked from perception cannot be remembered because they were never perceived. But, attention-control to emotional stimuli also varies with mood, as seen in mood-disorders. A mood-disorder’s effect upon the …

College Of Public Health News, Georgia Southern University

College of Public Health: News & Publications

• May 2020 Publications

Mental Health Screening For Low Income Adolescents: An Evidence-Based Project, Allison Bryden

Doctor of Nursing Practice Final Manuscripts

Abstract

TITLE: Mental Health Screening For Low-Income Adolescents

BACKGROUND: Nearly 80% of adolescents in the United States will suffer from a mental illness and not receive evaluation or services. Children from low socio-economic backgrounds have an increased risk of mental health disorders which permeate into adulthood, leading to additional negative sequel and lower quality of life. Among adolescent mental health conditions, depression and anxiety are the most common. Literature has suggested provider intuition alone has low sensitivity and specificity for detecting mental illness and that screening tools are indicated.

PURPOSE: The aim of this project is to implement standardized routine …