Medicine and Health Sciences Commons^™

Knowledge, Attitude, Practices, And Barriers Of Pharmacovigilance Among Healthcare Workers: A Cross-Sectional Survey From Lahore, Pakistan, Zia U. Mustafa, Muhammad Salman, Noman Asif, Alina Z. Rao, Qurat U.A. Khan, Asma S. Nawaz, Muhammad W. Mumtaz, Athar Masood, Muhammad F.A. Khan, Naureen Shehzadi, Khalid Hussain

Bulletin of Faculty of Pharmacy Cairo University

Background: Adverse drug reactions (ADRs) are associated with increased length of hospital stay, permanent disability and even death. Objectives: The purpose of this study was to assess knowledge, attitude, practice (KAP), and barriers related to Pharmacovigilance (PV) among Pakistani healthcare workers (HCWs). Methods: A cross-sectional study was conducted in the second largest metropolitan city (Lahore) of Pakistan during a period of 4 months (JuneeSeptember 2018). A self-administered questionnaire was used to collect data from the doctors, pharmacists, and nurses from 8 tertiary care hospitals, recruited via convenient sampling. All data were analyzed in SPSS version 21. Results: A total of …

Study The Effects Of Taurine Oral Supplement Used For Type 2 Diabetic Patients On Body Weight; Glycemic Control And Some Bone Mineralization Biochemical Markers, Falah Hassan Sheri, Hiba Dawood, Jubran K. Hassan, Qais A. Aljazaeari

Bulletin of Faculty of Pharmacy Cairo University

Background: Taurine is sulfur containing semi-essential amino acid that has important roles in many biological processes, but; its effects on glucose homeostasis, weight; growth and bone mineralization were not well defined in human. Objectives: evaluation the effects of oral taurine used for 3 months on bone mineralization biomarker; glycemic control and body weight in type II diabetic patients. Methods: interventional double-blind placebo-controlled study in which 80 patients with type2 diabetes mellitus (age range 45e55) assigned in either control (n ¼ 40) or study (n ¼ 40) group. The last group received 1000 mg capsule of taurine once a -d for …

Qbd Based Design And Characterization Of Proniosomal Transdermal Delivery Of Atenolol And Glibenclamide Combination: An Innovative Approach, P Anitha, S. Ramkanth, S. V. Satyanarayana

Bulletin of Faculty of Pharmacy Cairo University

There are numerous circumstances where chronic disease is associated with other disorders, especially in diseases like diabetes with noncommunicable disease risk factors, such as hypertension. This study shows a novel and innovative combinational proniosomal delivery of combination to beat the reactions by complex therapeutic regimen, and to improve patient compliance after controlling combinational transdermal delivery of Glibenclamide (GLB) and Atenolol (ATN) which have not been tried actually. To achieve the above reason, proniosomes were prepared and optimized utilizing Box-Behnken design. The ideal formulation was chosen by a point prediction method and formulation showed vesicle size of 562 ± 1.223 nm, …

The Use Of Natural Polymers In Formation Of Polyelectrolyte Complexation, Niharika Lal, Athira Nair, Navneet Verma

Bulletin of Faculty of Pharmacy Cairo University

In recent years, great advances have been made towards the development of various techniques for novel drug delivery systems. These techniques focus on the rate of drug delivery, duration of action and site of action. One of such technique in fabricating novel drug delivery system is the use of polymers in development of in-situ drug delivery systems. Polymers used as carriers have revolutionized over the years. The formation of a polymer complex with other oppositely charged polymers resulted in the formation of polyelectrolyte complexes, which possess unique physicochemical properties with high biocompatibility. The polyelectrolyte's themselves are characterized as cationic, anionic …

A Vista Of Kahana Bay, Haryashpal Bhullar

HCA Healthcare Journal of Medicine

This is a picture of Kahana Bay in Honolulu, HI I took when I was visiting my friend stationed at Tripler Army Medical Center last year. Like me, he is a Psychiatry resident and I had not seen him in over a year, so meeting him was quite meaningful to me as we had so much more to talk about. Having this vista behind us while we climbed and shared stories made for one of the best hikes of my life. I often look at this photo and realize the freedom we had to fly to all sorts of beautiful …

Corona, Syed Anjum Khan

HCA Healthcare Journal of Medicine

We all are witnessing unprecedented pain and suffering, enduring unsurpassed tribulations. As a doctor working in an intensive care unit each day, I carry the burden of my patients and their families, my coworkers, my own family and friends. I never think about myself, the burden on my soul.

Yet I believe there will be a better tomorrow. A new day, where COVID times will be remembered with tears in our eyes yet a comfort in our smile that it’s past.

Primary Care Practices In Western North Carolina: Adaptation To The Covid-19 Pandemic And Ongoing Challenges, Hannah R. Friedman, Joseph Konstanzer, Erica Richman, Brian Cass, Bryan Hodge, Sheri Denslow, Jacqueline Halladay

HCA Healthcare Journal of Medicine

Introduction

The COVID-19 pandemic has created unique challenges for primary care practices while also highlighting their importance in the pandemic response. To understand primary care practice needs, a survey was conducted of practices in Western North Carolina.

Methods

Phase 2 of a primary care needs assessment was administered to 63 practices in Western North Carolina over the course of six weeks, from July 23 to August 31, 2021.

Results

Most practices were operating with normal hours, though some still operated with reduced hours. Many practices reported insufficient personal protective equipment (PPE) supplies. While most practices provided at least some care …

An Assessment Of The Diagnostic Value In Syncope Workup: A Retrospective Study, Ashan T. Hatharasinghe, Kayvon Etebar, Ryan Wolsky, Hossein Akhondi, Napatkamon Ayutyanont

HCA Healthcare Journal of Medicine

Background

Patients with syncope often undergo costly testing, despite current guidelines and data supporting the contrary.

Objective

To determine the diagnostic value through positivity rate of electrocardiogram (EKG), computed tomography (CT) of the brain, magnetic resonance imaging (MRI) of the brain, transthoracic echocardiogram, nuclear and pharmacologic cardiac stress test, tilt table test and carotid ultrasound in patients diagnosed with syncope.

Methods

This is a retrospective study of 10,036 adults presenting to the emergency department or hospitalized with a primary diagnosis of syncope at 8 acute care facilities in the southwest United States from January 1, 2019, to December 31, 2019. …

Pharmacy-Led Medication Reconciliation Program Reduces Adverse Drug Events And Improves Satisfaction In A Community Hospital, L. Hayley Burgess, Joan Kramer, Carley Castelein, Joseph M. Parra, Victoria Timmons, Samantha Pickens, Sarah Fraker, Christopher Cameron Skinner

HCA Healthcare Journal of Medicine

Background

Pharmacy-led medication reconciliation identifies and corrects medication errors that can potentially cause moderate to severe harm. This research sought to identify the impact of pharmacy-led medication reconciliation on patient outcomes and describe the changes in healthcare workers’ perceptions of the program.

Methods

A pharmacy-led admission medication reconciliation program pilot started in July 2019, and a discharge medication reconciliation proof of concept was tested in September 2020 at a 432-bed hospital. The following periods were compared: August 2018 to February 2019 (pre-program implementation) and August 2019 to February 2020 (post-program implementation). Endpoints included patient outcomes, workforce productivity and interdisciplinary healthcare …

Jacuzzi-Induced Pneumoperitoneum: Case Report And Literature Review, Obteene Azimi-Ghomi, Dieter Brummund, Vasiliy Ovakimyan, Gerardo Kahane

HCA Healthcare Journal of Medicine

Radiographically-detected pneumoperitoneum in the setting of acute onset abdominal pain is a classic case among surgical emergencies. The spectrum of etiology ranges from benign to catastrophic, and the ability to differentiate depends in large part on the history and physical exam findings. Included among non-surgical types of pneumoperitoneum are (1) post-operative, (2) diagnostic/experimental, (3) gynecologic tract air entry, (4) the difference in intra- and extra-alveolar pressures, pneumothorax-associated and (5) miscellaneous. Jacuzzi-induced pneumoperitoneum is an extremely rare form of non-surgical pneumoperitoneum. We discuss a case of a 32-year-old female presenting with pneumoperitoneum and acute onset abdominal pain secondary to vaginal insertion …

Epidural Anesthesia For Cesarean Section For Parturient With Recently Diagnosed Asymptomatic Chiari Malformation Type I: A Case Report, Ashie Kapoor, Jon Halling

HCA Healthcare Journal of Medicine

Chiari malformations (CMs) are congenital defects of the brain and skull that result in inferior displacement of the cerebellum. There are four types of CMs distinguished by the severity of the anatomic defects and parts of the brain that protrude beyond the foramen magnum. Of these types, CM Type I (CMI) is the least severe. It is characterized by the downward displacement of the cerebellar tonsils beyond the foramen magnum by more than 5 millimeters and goes into the cervical spinal canal. CMI is the most common type with an incidence of 0.1-0.5% in the general population and a predominance …

Steroid-Refractory Lichenoid Eruption Associated With Pembrolizumab In A Patient With Non-Small Cell Lung Cancer, Leon Kou, Sanjay Agarwal, Alyssa Miceli, Logan Kolb, Karthik Krishnamurthy, Shawn Schmieder

HCA Healthcare Journal of Medicine

Programmed cell death receptor 1 (PD-1) inhibitors are promising and effective treatments for various cancers. Cutaneous adverse events, such as lichenoid drug eruptions, are well-known common side effects associated with PD-1 inhibitors. Lichenoid drug eruptions associated with PD-1 inhibitors show rapid improvement with high potency topical steroids and do not require cessation of the offending drug. We present the case of an 84-year-old female with progressive pembrolizumab therapy-associated lichenoid eruption that was resistant to several treatments and ultimately required discontinuation of pembrolizumab and treatment with methotrexate to resolve. This report includes histological findings of the pembrolizumab-associated lichenoid eruption.

The Role Of Physical Activity In Older Adults And Practical Intervention, Se Won Lee, Rebecca Patel, Bryan Werner, Ji Won Yoo, Timothy Tiu

HCA Healthcare Journal of Medicine

Physical inactivity (PI), defined as not meeting guidelines for physical activity beyond baseline daily living activities, is common among older adults (age 65 and older) and contributes to increased morbidity, increased mortality and increased health care spending. Understanding the clinical impact of PI on common medical conditions among older adults will help primary care physicians (PCPs) to educate these patients successfully. Physical activity and exercise are effective in the primary and secondary prevention of chronic diseases that can lead to physical impairments, disability and/or premature death. Physical activity and exercise have been shown to improve cognitive dysfunction and painful musculoskeletal …

Effect Of Sesamol On Biochemical Changes In Diet Induced Obesity (Dio) Model Of Zebra Fish (Danio Rerio), Rashmi Ks

Faculty work

No abstract provided.

Thickness And Width Of The Menisci Of Adult Knee Joint, A Cadaveric Study, B.V. Murlimanju

Faculty work

No abstract provided.

Morphological Study Of The Transverse Ligament Of The Knee Joint In Embalmed Cadavers, B.V. Murlimanju

Faculty work

No abstract provided.

Problems Of Training Qualified Personnel For The Sphere Of Physical Culture And Sports, Abdimalik Nurullaevich Shopulatov

Eurasian Journal of Sport Science

Purpose: To study the issues aimed at increasing the knowledge and experience in the effective use of physical culture and sports in the restoration of public health, as well as to analyze the work being done to train qualified personnel in the field of physical culture and sports and identify problems.

Methods: Methods such as analysis of scientific and methodological literature, pedagogical observation, questionnaire were used in the study.

Results: From the research it was revealed that today it is important to develop the knowledge of the population on physical education and sports, that is, to create educational and scientific …

Analysis Of General And Special Physical Training Of Qualified Greco-Roman Wrestlers, Eldor Tolibjonovich Rakhmonov

Eurasian Journal of Sport Science

Aim: Study and analysis of the features of general and special physical training of qualified Greco-Roman wrestlers.

Methods: The level of development of physical qualities and motor skills of Greco-Roman wrestlers, ensuring the effective performance of combinatorial movements in competitions, was determined using test methods compiled with special exercises that allow determining the level of general and special physical training. Also in the course of the study, the analysis of scientific and methodological literature, pedagogical observation, questionnaires, mathematical statistics were widely used.

Results: In the control group, it was found that the average relative difference between the general and specific …

Protective Role Of Cod Liver Oil On Metabolic And Neurological Parameters In Rat Model Of Diabetic Depression, Roweena Sheryl

Kasturba Medical College, Mangalore Theses and Dissertations

No abstract provided.

Nutritional Status Of Children Living Within Institution-Based Care: A Retrospective Analysis With Funnel Plots And Control Charts For Programme Monitoring, Emily Delacey, Evan Hilberg, Elizabeth Allen, Michael Quiring, Cally J. Tann, Nora Ellen Groce, James Vilus, Ethan A. Bergman, Merzel Demasu-Ay, Hang T. Dam, Marko Kerac

All Faculty Scholarship for the College of Education and Professional Studies

Objectives The aim of this study is to fill a key information gap on the nutrition-related epidemiology of orphaned and vulnerable children living within institution-based care (IBC) across six countries.

Design A retrospective analysis with Shewhart control charts and funnel plots to explore intersite and over time variations in nutritional status.

Setting We conducted a retrospective analysis of records from Holt International’s Child Nutrition Programme from 35 sites in six countries; Mongolia, India, Ethiopia, Vietnam, China and the Philippines.

Participants Deidentified health records from Holt International’s online nutrition screening database included records from 2926 children, 0–18 years old. Data were …

Coronavirus Update 12-30-21, The Coronavirus Planning Team

University Briefings & Virtual Events

What to Do If You Test Positive During Break -- Masking -- Social Distancing -- Stay Home if You Feel Sick -- Testing for Employees -- Booster Clinics -- Study and Travel Abroad.

Consequential Surgeries Limit Recurrence Of Skin Malignancies In Xeroderma Pigmentosum: A Case Report, Ahmad Kurnia, Diani Kartini, Novinda Herwirastri, Zoya M. Adyasa

The New Ropanasuri Journal of Surgery

Xeroderma Pigmentosum (XP) is a rare inherited skin malignancy with no causative treatment options. Reporting a 23-year-old woman with xeroderma pigmentosum who underwent several surgical tumor removals followed by further five procedures to apply tissue expander, facial resurfacing using full-thickness skin grafts with a donor from abdominal. The next series was tumor resection in the chin, forehead, nasal reconstruction, tumor removal on bilateral third digits, and defect closure. No recurrence after nine years of postoperative monitoring with an aesthetically acceptable result.

Different Approaches Of Suspected Unilateral And Bilateral Maxillary Sinus Myxoma, Two Rare Cases Report, Marlinda Adham, Ferucha Moulanda

The New Ropanasuri Journal of Surgery

Maxillary sinus myxoma is a rare benign tumor with locally aggressive behavior and can infiltrate surrounding structures. Surgical intervention is considered the primary procedure with several approaches for wider tumor exposure, complete tumor removal, and better wound healing. In this article, two cases of suspected unilateral and bilateral maxillary sinus myxoma were presented with different approaches applied for both cases. We managed two patients, a 37-year-old male with mass at right maxilla and a 60-year-old male with mass at both maxillae. Physical examination, radiology imaging, and pre-operative histopathology examination showed maxillary sinus myxoma. The total maxillectomy procedure with Weber Ferguson …

Factors Affecting Renal Function On Ileostomy In Dr. Cipto Mangunkusumo General Hospital: A Cross-Sectional Study, Lam Sihardo, Agi S. Putranto

The New Ropanasuri Journal of Surgery

Introduction. Every year, about 30—60 ileostomy with various underlying diseases and indications were created in Dr. Cipto Mangunkusumo General Hospital (CMGH). There were a lot of complications attributable to these creations; one is the decline of renal function. The study goal was to find out factors influencing the renal function of ileostomy in CMGH.

Method. A cross-sectional study was conducted using medical records in April – May 2021. Samples were taken using the purposive sampling method. Inclusion criteria include male or female patients who underwent ileostomy closure in CMGH in the last four years with complete BMI, ileostomy creation and …

Survival Rate Of Critically Ill Coronavirus Disease 2019 Patients On Tracheostomy In Indonesia, Aris Ramdhani, Dita Aditianingsih, Raihanita Zahra, Muhammad A. Putra, Wuryantoro Soeharto, Melvin D.B. Kwa

The New Ropanasuri Journal of Surgery

Introduction. During COVID-19 global pandemic, tracheostomy is often performed on critically ill COVID-19 patients. There is no available data on the survival rate of critically ill COVID-19 patients on tracheostomy in Indonesia. This study aimed to find the survival rate of critically ill COVID-19 patients on tracheostomy in Indonesia.

Methods. A descriptive survival analysis study enrolled critically ill COVID-19 patients in RSUI who underwent a tracheostomy procedure. Baseline data, including clinical characteristics and laboratory findings before tracheostomy, were recorded. Survival analysis was conducted using the Kaplan-Meier plot.

Results. Forty-two subjects were enrolled in the study: 25 males (59.5%) and 17 …

The New Version Of Accreditation For Higher Education In Health, Yefta Moenadjat

The New Ropanasuri Journal of Surgery

No abstract provided.

Prognostic And Predictive Factors Of Mortality In Burn Patients At Dr. Cipto Mangunkusumo General Hospital, Indonesia, Muhamad Irfan A. Hasibuan, Yefta Moenadjat

The New Ropanasuri Journal of Surgery

Introduction. Some prognostic– and predictive factors in burn have never been investigated in Indonesian specific characteristics, which is delayed treatment. A study was conducted to determine prognostic and predictive factors in this specific characteristic.

Method. A retrospective cohort focused on burn mortality in extensive burns managed in CMGH from 1998–2010. Some known prognostic– and predictive factors and unknown ones were the variables of interest. Bivariate and multivariate using logistic regression analysis proceeded to find out these factors.

Results. Out of all factors investigated, the variables that showed a significant correlation were: TBSA, inhalation injury, Baux score, revised …

Cutaneous Horn On The Right Supraclavicular Region In An Adolescent Female, A Rare Case Report, Rohit Gupta, Manoj Kumar, Ruchi Sinha, Reva Shankar Sahu

The New Ropanasuri Journal of Surgery

Cutaneous horn (CH) is an outgrowth from the skin surface, composed of keratin, and associated with benign to malignant skin lesions. We report a case of CH in a 15-year-old female associated with Keratoacanthoma. It is uncommon in young people and is associated with a good prognosis because of its benign nature. This case needs to be reported as it highlights the rare occurrence of this condition in the younger age group and its good prognosis. Surgical excision is the treatment of choice, with histopathologic diagnosis playing a critical role in determining the nature and further treatment of this condition …

Association Between Cigarette Smoking And Breast Milk Levels Of Nesfatin-1, Irisin, And Oxidative Stress Markers, Nesibe Yildiz, Adnan Yilmaz, Hatice Iskender, Eda Dokumacioglu

Makara Journal of Health Research

Background: Breast milk is a very important functional food in the prevention of metabolic and chronic diseases. This study aimed to investigate the effects of smoking during pregnancy on the concentrations of nesfatin-1, irisin, and oxidative stress markers in breast milk.

Methods: This study included two groups of 14 smoking and 14 nonsmoking mothers. Malondialdehyde (MDA) level and superoxide dismutase (SOD) activity were measured according to the spectrophotometric method in breast milk samples. Nesfatin and irisin levels were measured by enzyme-linked immunosorbent assay.

Results: Levels of nesfatin-1 and MDA of the smoking group were significantly higher than …

Ectodermal Dysplasia: A Review, Yasemin Yavuz, Mehmet Sinan Doğan, Myroslav Goncharuk-Khomyn

Makara Journal of Health Research

Background: Ectodermal dysplasia is a complex group of genetic disorders identified through the abnormal development of ectodermal structures. It is a genetic disorder that affects the development or functions of tissues such as the teeth, hair, nails, and sweat glands.

Methods: This review aimed to introduce the outcomes and increase awareness of ectodermal dysplasia reviewing by the literature.

Results: The characteristic features of this disease, including hypodontia, hypohidrosis, and hypotrichosis, have been discussed.

Conclusions: Ectodermal dysplasia is a heterogeneous group of hereditary disorders with similar clinical findings. It leads to the development of tissue malformations and …