Medicine and Health Sciences Commons^™

Yeast Particle Encapsulation Of Scaffolded Terpene Compounds For Controlled Terpene Release, Ernesto R. Soto, Florentina Rus, Hanchen Li, Carli Garceau, Jeffrey Chicca, Mostafa Elfawal, David Gazzola, Martin K. Nielsen, Joseph F. Urban Jr., Raffi V. Aroian, Gary R. Ostroff

Maxwell H. Gluck Equine Research Center Faculty Publications

Terpenes are naturally occurring compounds produced by plants that are of great commercial interest in the food, agricultural, cosmetic, and pharmaceutical industries due to their broad spectra of antibacterial, antifungal, anthelmintic, membrane permeation enhancement, and antioxidant biological activities. Applications of terpenes are often limited by their volatility and the need for surfactants or alcohols to produce stable, soluble (non-precipitated) products. Yeast particles (YPs) are hollow, porous microspheres that have been used for the encapsulation of terpenes (YP terpenes) by passive diffusion of terpenes through the porous YP cell walls. We here report the development of a second generation YP encapsulated …

Commencement, Georgia (2021), Philadelphia College Of Osteopathic Medicine

Commencements

Georgia Campus Commencement program, Class of 2021. Degrees include Doctorate in Osteopathic Medicine, Doctorate in Pharmacy, and Doctorate in Physical Therapy.

Long-Term Outcomes In Children With Acute Flaccid Myelitis, Megan D. Henley, Lindie Hill, Sydney Inman, Molly Grace King, Sam Lopez, Carley Mahaffey

Master of Occupational Therapy Student Critically Appraised Topics

The purpose of our critically appraised topic is to combine the best evidence regarding the long-term outcomes in children with acute flaccid myelitis (AFM) regarding posture and movement, gross and fine motor control, and activities of daily living (ADL) performance. The final portfolio contains eight articles. The study designs of these articles include a retrospective cohort study, two retrospective non-randomized studies without a control group, a retrospective review, a nationwide follow-up questionnaire analysis study, a case report, a case series, and a multiple quantitative case study. All studies related directly to our evidence-based PICO question and were used to determine …

Exercise Interventions For Adults With Burn Injuries, Liz Burton, Carolyn Knight, Brittney Malone, Lexie Rivers, Rachel Walker, James Wright

Master of Occupational Therapy Student Critically Appraised Topics

The purpose of this critically appraised topic (CAT) is to provide the highest quality of evidence available on the implementation of exercise interventions in the early burn rehabilitation phase in adult burn victims. This portfolio contains four peer-reviewed research articles from national and international journals. The study designs include one systematic review and meta analyses, one retrospective cohort study and two randomized control trials. These articles covered three types of exercise interventions including resistance training, mobility training, and physiotherapy. Overall, the clinical bottom line of this CAT is that exercise interventions in early burn rehabilitation may be effective in improving …

Reducing Stress, Anxiety, And Depression For Nicu Parents, Amy Patton, Kylie Dunavan, Kyla Key, Steffani Takahashi, Kathryn Tenner, Megan Wilson

Master of Occupational Therapy Student Critically Appraised Topics

This project aims to appraise evidence of the effectiveness of various practices on reducing stress, anxiety, and depression among parents of infants in the neonatal intensive care unit (NICU). The project contains six research articles from both national and international journals. Study designs include one meta-analysis, one randomized controlled trial, one small scale randomized controlled trial, one prospective phase lag cohort study, on pretest-posttest study, and one mixed-methods pretest-posttest study. Recommendations for effective interventions were based on best evidence discovered through quality appraisal and study outcomes. All interventions, except for educational programs and Kangaroo Care, resulted in a statistically significant …

Violence And Abuse Among Working Children In Urban And Suburban Areas Of Lower Sindh, Pakistan, Meesha Iqbal, Zafar Fatmi, Kausar S. Khan, Asaad Ahmed Nafees

Community Health Sciences

Background: Child labourers are exposed to an insecure environment and higher risk of violence. Violence among child labourers is an under-studied phenomenon which requires contextual assessment.
Aims: We applied Bronfenbrenner's ecological model (micro-, exo- and macro-system) to understand the interplay of individual, community, societal and policy context fuelling violence.
Methods: Focus group discussions and family ethnographies of child-labourers working in common occupational sectors of suburban areas of Sindh were carried out to gain in-depth understanding of their immediate environment and abuse (micro-system). Frequency of emotional, physical and sexual violence (5-14 years; n = 634) was also determined. Indepth interviews with …

Digital Technology Needs In Maternal Mental Health: A Qualitative Inquiry, Alexandra Zingg, Laura Carter, Deevakar Rogith, Amy Franklin, Sudhakar Selvaraj, Jerrie Refuerzo, Sahiti Myneni

Faculty, Staff and Student Publications

Digital technologies offer many opportunities to improve mental healthcare management for women seeking pre- and-postnatal care. They provide a discrete, practical medium that is well-suited for the sensitive nature of mental health. Women who are more prone to experiencing peripartum depression (PPD), such as those of low-socioeconomic background or in high-risk pregnancies, can benefit the most from such technologies. However, current digital interventions directed towards this population provide suboptimal support, and their responsiveness to end user needs is quite limited. Our objective is to understand the digital terrain of information needs for low-socioeconomic status women with high-risk pregnancies, specifically within …

Impact Of Local Terminology On The Design Of A Community-Based Diagnostic And Management Algorithm For Postpartum Sepsis: Findings Of Formative Research, Shabina Ariff, Fatima Mir, Wafa Aftab, Farrukh Raza, Shujaat Zaidi, Sheraz Memon, Amnesty Lefevre, Linda A. Bartlett, Peter Winch, Sajid Bashir Soofi, Zulfiqar Ahmed Bhutta

Department of Paediatrics and Child Health

Background: Postpartum sepsis is one of the leading causes of maternal mortality and morbidity in developing countries. This formative research elicits local terms used for postpartum illnesses and symptoms of postpartum sepsis with the aim of improving postpartum diagnosis and management in Pakistan.
Methods: We conducted 34 in-depth interviews with recently delivered women (RDW), traditional birth attendants (TBAs), healthcare providers and family members of RDW from rural Sindh to explore local Sindhi terms used to describe postpartum sepsis and related symptoms. During interviews, all participants were asked to orally free list common symptoms of postpartum illnesses; those who were aware …

Plasma Adenosine Deaminase (Ada)-1 And -2 Demonstrate Robust Ontogeny Across The First Four Months Of Human Life., Oludare A. Odumade, Alec L. Plotkin, Jensen Pak, Olubukola T. Idoko, Matthew A. Pettengill, Tobias R. Kollmann, Al Ozonoff, Beate Kampmann, Ofer Levy, Kinga K. Smolen

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Background: Human adenosine deaminases (ADAs) modulate the immune response: ADA1

Methods: In a subgroup of the EPIC002-study, clinical data and plasma samples were collected from 540 Gambian infants at four time-points: day of birth; first week of life; one month of age; and four months of age. Concentrations of total extracellular ADA, ADA1, and ADA2 were measured by chromogenic assay and evaluated in relation to clinical data. Plasma cytokines/chemokine were measured across the first week of life and correlated to ADA concentrations.

Results: ADA2 demonstrated a steady rise across the first months of life, while ADA1 concentration significantly decreased 0.79-fold …

Characterizing Receptive Vocabulary Knowledge In Minimally Verbal Children With Autism Spectrum Disorder, Allison Menting

LSU Master's Theses

Background: Delayed or impaired language skills are common characteristics of children with autism spectrum disorder (ASD). Currently, there is little research examining the receptive language profile in children with ASD, and even less is known about children with ASD who are minimally verbal. The current study aimed to characterize the receptive vocabulary profile of minimally verbal children with ASD and to examine whether this profile differs from their typically developing peers. Methods: Participants included 31 minimally verbal children with ASD, aged 60-118 months, who were reported to produce between 0-10 words, 124 typical developing toddlers, aged 9-14 months, who were …

They Used Expressive Writing With Their Therapist, Lindsay Mccue

School of Psychology, Family, and Community Research Conference

This study aims to explore the effect that expressive writing could have as an intervention for improving self-compassion, anxiety, depression, and stress associated with relational distress in a therapeutic environment. Participants will be split into two groups, and both will attend therapy with a focus on a relational problem in their life. The control group will receive 8 talk therapy sessions, while the intervention group will receive 5 talk therapy sessions and 3 sessions focusing on an expressive writing assignment. Participants will be screened for recent traumatic events, will need to be over the age of 18, and will need …

Narrative Therapy Effectiveness In Adult Patients Undergoing Chemotherapy Cancer Treatment, Gretchen Hoyum

School of Psychology, Family, and Community Research Conference

It is very common for cancer patients to experience depression while undergoing treatment (Vega et al., 2014). Previous studies have tested the effectiveness of several types of therapeutic interventions for depression in cancer patients. However, few studies have focused on the use of narrative therapy specifically in this population. This study seeks to test the effectiveness of narrative therapy for cancer patients currently undergoing chemotherapy treatment using the PHQ-9 and White's maps of narrative therapy (Kroenke et al. 2001; 2007).

How Effective Is Polyvagal Theory On The Long-Term Reduction Of Ptsd Symptoms In Adolescents?, Kristyna Richards

School of Psychology, Family, and Community Research Conference

This longitudinal study is focused on using the Polyvagal theory and identifying its efficiency in reducing PTSD symptoms in adolescents between the ages of 13-18. Launching into early adulthood with a dysregulated nervous system presents challenges for the client both physiologically and psychologically. While talk-therapy is effective in helping a client psychologically process the trauma, it often does not address the clients physiological state of the stored trauma. Without intervention to the clients physiological system, symptoms of the PTSD can persist and increase risk for psychological and physical comorbidities as well as increase the likelihood of intergenerational trauma within relational …

Exploring The Therapeutic Alliance In Eft When Addressing Race And Cultural Differences., Ashley Kortman, Deyja Kauffman

School of Psychology, Family, and Community Research Conference

This study aims to explore the therapeutic alliance in EFT when addressing race and cultural difference between a non-white client and a white therapist. This quantitative study will survey 100 non-white clients receiving therapy from a white therapist. Subjects will participate in 10 sessions of therapy with a white therapist practicing EFT. Half of the clients will see a traditional EFT therapist, while the other half will see an EFT therapist who has gone through specialized training in cultural attunement. Using a modified Helping Alliance Questionnaire (Luborsky, et al. 1996), with additional questions concerning race and culture, we will measure …

Implications Of Cultural Awareness On Healthcare Access In Marginalized Communities, Allison Davis, Diana Melman

School of Psychology, Family, and Community Research Conference

While the Covid-19 pandemic has had global effects, community inequalities have led to a diversity of specific impacts. Covid-19 has specifically impacted marginalized communities at a higher rate, and a common theme has emerged highlighting a disparity in healthcare access, leading to these communities being left behind. As current literature is being released during the pandemic, data has uncovered some technical details of new challenges in healthcare access. In addition, individuals from marginalized communities may place a higher importance of cultural competency in their health care. This proposal aims to identify the ways in which access to telehealth has impacted …

Integration Of Systemic Family Therapy And Attachment-Focused Approach With Adoptive Families: Impacts On Attachment In Child-Parent Interactions, Julianne Park

School of Psychology, Family, and Community Research Conference

Attachment deficits are prevalent among adoptive children especially after their first year in adoption (van den Dries, 2009). While treatment with the focus on the attachment needs of adopted children and adoptive parents’ attunement has been increasingly discussed, not much has been researched on the effectiveness of the family systems approach, including the exploration of the parents’ emotional experiences around adoption. In addition, more studies that strictly focus on treating adoptive children’s attachment issues after their first year of adoption are needed. By incorporating the Taking Care of Adoption (TCA) model, which is based on the integration of a family …

Assessing Effectiveness Of Minecraft-Based Interventions To Improve Interpersonal Skills Of Youth With Autism Spectrum Disorder, Linh Truong, Susan Dorn

School of Psychology, Family, and Community Research Conference

Teenagers with Autism Spectrum Disorder (ASD) experience bullying and social exclusion more than typically developing teens which can lead to feelings of depression and anxiety. These consequences are related to significant impairments in social reciprocity, a core feature of ASD. Face-to-face social skills training (SST) like the Program for the Education and Enrichment of Relational Skills) for Adolescents (PEERS) has been found to increase social skills for youth with ASD. Can these SSTs be brought online? Minecraft, a versatile online platform and a shared language among teenagers across the globe has been used therapeutically to increase social skills (i.e. social …

Cultural Values And Sexual Satisfaction In Interracial Relationships, Alisha Le Beau, Sierra Phelps

School of Psychology, Family, and Community Research Conference

This research aims to investigate cultural values in interracial couples and its impact on sexual satisfaction. Participants will be recruited to volunteer from interracial couple support groups in Washington state. Based on self-report, we will gather demographic information about our participants’ gender, race, age, relationship status, identified cultures, and faith background. We predict that the greater the differences between cultural value sets and expectations within an interracial couple, the more communication and potential compromise will be needed in order to achieve sexual satisfaction. Therefore, we hypothesize that increased differences in cultural values will decrease sexual satisfaction within interracial couples.

Impact Of Racism On The Use Of Intrusive Interventions, Marissa Mackey

School of Psychology, Family, and Community Research Conference

The American law enforcement’s disproportionate maltreatment and violence against the BIPOC community has become a mainstream social issue. Since racism and discrimination have been interwoven into American society since the country’s origin it is negligent to think that differential and unfair treatment starts and ends with police. Using the data from this study we will examine the relationship between racial minority status and the rate of use of intensive interventions such as restraints and seclusion in inpatient mental health facilities. The results of this study can be used to inspire future research into how to create equity within inpatient organizations, …

Measuring Countertransference And Self-Care For Therapists During Covid-19 And Telehealth, Elliott Duea

School of Psychology, Family, and Community Research Conference

The sudden onset of a global pandemic put therapists in a unique position; therapists that have always practiced in an office found themselves providing therapy from their homes. With this change, this study seeks to measure two things: the first goal of this study is to determine if therapists have encountered more instances of countertransference since practicing in their homes. And the second goal of the study is to determine if it has been more difficult to practice self-care since seeing clients at home over telehealth.

Effectiveness Of Telehealth In Treating Eating Disorders, Kylee Hellstern, Julia Robison

School of Psychology, Family, and Community Research Conference

Eating disorders have been increasing in severity and frequency during the COVID-19 pandemic. Individuals are experiencing lockdown, isolation, increased fear of exposure and contraction, and disruption in regular routine. Clients and clinicians are being encouraged to conduct therapy virtually and through a screen. While almost all treatment has been moved online, little to no research has been done on telehealth’s effectiveness on treatment of eating disorders. The purpose of this proposed study is to collect quantitative data on the effectiveness of telehealth as a means of treatment for eating disorders during the COVID-19 pandemic.

Effects Of Trauma-Informed, Culturally Adaptive Efit Among U.S. Cambodian Refugees, Liane Whang

School of Psychology, Family, and Community Research Conference

The aim of this study is to evaluate the effects of culturally adaptive, trauma-informed Emotionally Focused Individual Therapy (EFIT) on Cambodian refugees with PTSD, depression, and/or somatic symptom disorder. Participants will be drawn from a geographical area with the largest concentration of Cambodian Americans in the Seattle, Washington area. Eligible participants are adults who have been diagnosed with PTSD, major depression, and/or somatoform disorders who have lived in Cambodia at some point during the Khmer Rouge regime before resettling in Seattle. Half of the participants will be offered trauma-focused EFIT while the other half will receive their usual psychiatric and …

Effectiveness Of Emotionally Focused Family Therapy (Efft) In Adults Experiencing Anorexia Nervosa., Lea Fingerhut

School of Psychology, Family, and Community Research Conference

Anorexia nervosa (AN) is one of the most lethal and debilitating psychiatric disorders with a long recovery rate, underscoring the need for efficacious treatment. Although research has made significant advances in individual and systemic treatment options for AN, none have examined the use of family-based treatment options with adults experiencing AN. The following study aims to explore the efficacy of emotionally-focused family therapy (EFFT) in the treatment of AN.

Life Satisfaction In Family Caregivers Taking Care Of Someone With Dementia: A Comparison To Informal Caregivers And Non-Caregivers., Raelynn Johnston

School of Psychology, Family, and Community Research Conference

There are an estimated 30 million individuals with dementia and that number is likely to doubles every twenty years. Individuals with dementia typically need additional support, which comes from caregivers. It is important to look at the life satisfaction of caregivers, both family and informal, compared to non-caregivers (Brodaty & Donkin, 2009). Caregivers experience higher rates of depression, stress, health complications, and lower rates of life satisfaction (Borg & Hallberg, 2006). This has clinical implications as it can demonstrate how therapists can provide resources and tools for caregivers to reduce depression, stress, and burden. This study aims to explore the …

Is Solution-Focused Brief Therapy In School-Based Settings Effective In Reducing Self-Harm Tendency Behaviors In Adolescents?, Enas Albar, Violet Ohsiek

School of Psychology, Family, and Community Research Conference

About 16% of adolescents have engaged in deliberate self-harm (Muehlenkamp et al., 2012). These adolescents will experience a range of negative effects and can possibly engage in other high-risk behaviors (Westers & Plener, 2020). Solution-focused brief therapy is known to be cost-effective and applicable in school-based settings (Szlyk, 2018). Since teens are more likely to receive support in school settings, examining the effectiveness of SFBT is beneficial. Applying solution-focused brief therapy in a school-based setting will decrease self-harm tendency behaviors in adolescents. Our sample size will include both male and female participants ages 12-18 years old. Using data from collected …

Association Of Emotional Intelligence Of Primigravida Mothers With Breastfeeding Self Efficacy In The Early Postpartum Period And Exclusive Breastfeeding Rates Up To 6 Months., Priyanka Reddy P

Kasturba Medical College, Mangalore Theses and Dissertations

No abstract provided.

2021-05-26_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …

2021-05-26_Michiganoverview_Covidtestingtimes, Michigan Department Of Health & Human Services

Michigan COVID-19 Testing Turnaround Data

The COVID Testing Turnaround Time page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173-545615--,00.html.

This report was created by the Michigan Department of Health & Human Services, providing data for the past 14 days on the average time it takes for a diagnostic COVID-19 laboratory test to be reported to the state health department. Testing turnaround time data will be updated weekly on Friday mornings.

MDHHS receives results from commercial labs, hospitals, and public health labs. However, public health laboratories perform limited diagnostic testing and disease surveillance for infectious diseases. Total turnaround time is calculated from the difference of …

2021-05-26_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled. It is updated Monday - Saturday.
This report is provisional and subject to change. City of Detroit and Wayne County are reported separately. MDHHS began tracking probable cases April 5, 2020. FCI indicates federal correctional institute. MDOC indicates Michigan Department of Corrections. Diagnostic tests, including nucleic acid amplification/real-time polymerase chain reaction (NAAT/RT-PCR) and rapid virus antigen detection point of …

Phenolic Compounds Of Red Wine Aglianico Del Vulture Modulate The Functional Activity Of Macrophages Via Inhibition Of Nf-Κb And The Citrate Pathway, Anna Santarsiero, Paolo Convertini, Antonio Vassallo, Valentina Santoro, Simona Todisco, Dominga Iacobazzi, Yvonne N. Fondufe-Mittendorf, Giuseppe Martelli, Marcos R. De Oliveira, Rosangela Montanaro, Vincenzo Brancaleone, Johannes Stöckl, Vittoria Infantino

Molecular and Cellular Biochemistry Faculty Publications

Phenolic compounds of red wine powder (RWP) extracted from the Italian red wine Aglianico del Vulture have been investigated for the potential immunomodulatory and anti-inflammatory capacity on human macrophages. These compounds reduce the secretion of IL-1β, IL-6, and TNF-α proinflammatory cytokines and increase the release of IL-10 anti-inflammatory cytokine induced by lipopolysaccharide (LPS). In addition, RWP restores Annexin A1 levels, thus involving activation of proresolutive pathways. Noteworthy, RWP lowers NF-κB protein levels, promoter activity, and nuclear translocation. As a consequence of NF-κB inhibition, reduced promoter activities of SLC25A1—encoding the mitochondrial citrate carrier …