Medicine and Health Sciences Commons^™

Epidemiology, Pathogenesis, And Clinical Manifestations Of Acute Esophageal Necrosis In Adults, Obaid Rehman, Urooj Jaferi, Inderbir Padda, Nimrat Khehra, Harshan Atwal, Mayur Parmar

HPD Articles

Acute esophageal necrosis (AEN), also termed "black esophagus," is a unique and uncommon occurrence observed in severely sick patients. Other terminologies include acute necrotizing esophagitis and Gurvits syndrome. This condition is described as a darkened distal third of the esophagus observed on endoscopy and presents as an upper gastrointestinal (GI) bleed, difficulty swallowing, abdominal pain, fever, syncope, nausea, and vomiting. The etiology of AEN has been linked to several possibilities, such as excessive gastric acid reflux, hypoperfusion, and ischemia due to impaired vascular supply and hemodynamic instability. Risk factors include increased age, sex (male), heart disease, hemodynamic insufficiency, alcohol use, …

Long Non-Coding Rnas And Their Targets As Potential Biomarkers In Breast Cancer., Maryam Khalid, Rehan Zafar Paracha, Maryum Nisar, Sumaira Malik, Salma Tariq, Iqra Arshad, Amnah Siddiqa, Zamir Hussain, Jamil Ahmad, Amjad Ali

Faculty Research 2021

Breast cancer is among the lethal types of cancer with a high mortality rate, globally. Its high prevalence can be controlled through improved analysis and identification of disease-specific biomarkers. Recently, long non-coding RNAs (lncRNAs) have been reported as key contributors of carcinogenesis and regulate various cellular pathways through post-transcriptional regulatory mechanisms. The specific aim of this study was to identify the novel interactions of aberrantly expressed genetic components in breast cancer by applying integrative analysis of publicly available expression profiles of both lncRNAs and mRNAs. Differential expression patterns were identified by comparing the breast cancer expression profiles of samples with …

Network Topology Of Biological Aging And Geroscience-Guided Approaches To Covid-19., Alan Landay, Jenna Bartley, Dishary Banerjee, Geneva Hargis, Laura Haynes, Ali Keshavarzian, Chia-Ling Kuo, Oh Sung Kwon, Sheng Li, Shuzhao Li, Julia Oh, Ibrahim Tarik Ozbolat, Duygu Ucar, Ming Xu, Xudong Yao, Derya Unutmaz, George A Kuchel

Faculty Research 2021

Aging has emerged as the greatest and most prevalent risk factor for the development of severe COVID-19 infection and death following exposure to the SARS-CoV-2 virus. The presence of multiple co-existing chronic diseases and conditions of aging further enhances this risk. Biological aging not only enhances the risk of chronic diseases, but the presence of such conditions further accelerates varied biological processes or "hallmarks" implicated in aging. Given growing evidence that it is possible to slow the rate of many biological aging processes using pharmacological compounds has led to the proposal that such geroscience-guided interventions may help enhance immune resilience …

2021-07-01_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled. It is updated Monday - Friday.
This report is provisional and subject to change. City of Detroit and Wayne County are reported separately. MDHHS began tracking probable cases April 5, 2020. FCI indicates federal correctional institute. MDOC indicates Michigan Department of Corrections. Diagnostic tests, including nucleic acid amplification/real-time polymerase chain reaction (NAAT/RT-PCR) and rapid virus antigen detection point of …

Cerebellum-Seeded Functional Connectivity Changes In Trait-Anxious Individuals Undergoing Attention Bias Modification Training, Katherine Elwell

All NMU Master's Theses

Anxiety and anxiety related disorders are increasing at a drastic rate in the past decade, with the NIMH reporting that 31.1% of U.S. adults will experience an anxiety disorder at some point in their lives. Anxiety is commonly characterized by increased attention bias to threat. Attention Bias Modification (ABM) is a new treatment used to reduce individual’s attention bias towards threat. The extent to which ABM leads to underlying neural changes is still unknown. The cerebellum is a neglected brain structure, with new research provides evidence that cerebellum’s functional connectivity and shared networks with threat processing regions has a direct …

The Innovator - Summer 2021, Allison Litera

Faculty Affairs & Research Newsletters - The Innovator

Newsletter published by the Offices of Faculty Affairs & Research

Use Of Ultrasonic Aspirator For Cns Tumour Resection, Noman Ahmad, Saqib Kamran Bakhshi, Muhammad Shahzad Shamim

Section of Neurosurgery

Ultrasonic aspirator (UA), or the Cavitron Ultrasonic Aspirator (CUSA) as it is commonly referred to, utilizes ultrasonic waves of variable range of frequencies to disintegrate and excise tumours. It is developed as a substitute of bipolar diathermy; a tool commonly employed for coagulation that uses focussed electric current and may damage tissues by virtue of contact, or by the heat that it produces. Over the last 30 years, CUSA has become increasingly popular in several soft tissue surgeries, especially brain and spine tumour resection, as it allows reduction in the use of bipolar diathermy. It is assumed that CUSA improves …

Macomb Dental Society Journal Summer 2021

Journal of the Macomb Dental Society

In the Summer 2021 issue, the reader will find the following feature articles:

• Timing Your Next Real Estate Transaction
• 2021 Oakland, Macomb, Wayne Counties Golf Outing

Also included are regular columns from the President, Executive Director and Editor, as well as news shorts and information on upcoming events.

Increasing Pneumococcal Polysaccharide Vaccination Rates In Adults Age 65 Years And Older In A Primary Care Clinic, Ashley Sandbothe

Doctor of Nursing Practice Scholarly Project

The purpose of this study was to increase PPSV23 vaccination rates in adults over the age of 65 years in a Midwestern primary care clinic.

For this project, staff was educated regarding interventions including patient awareness, provider recommendation, staff and provider education, vaccine access, use of the immunization information systems (IIS) and appropriate use of electronic health record (EHR) reminders that have been shown to increase vaccination rates.

Prior to the intervention, data was retrieved, and it was found that between April 1^st-May 31^st 2020, there were 162 patients over the age of 65 that presented to …

The Magnetic Couples Study: Protocol For A Mixed Methods Prospective Cohort Study Of Hiv-Serodifferent Heterosexual Couples’ Perspectives And Use Of Pre-Exposure Prophylaxis (Prep), James M. Mcmahon, Janie Simmons, Jessica E. Haberer, Sharon Mannheimer, Natalie M. Leblanc, Leilani Torres, Robert Quiles, Guillermo Aedo, Anabel Javier, Amy Braksmajer, Graham Harriman, Nicole Trabold, Enrique R. Pouget, Ann Kurth, Martez D. R Smith, Judith Brasch, Eric J. Podsiadly, Peter L. Anderson

Publications and Research

Introduction HIV transmission within serodifferent heterosexual couples plays a key role in sustaining the global HIV pandemic. In the USA, transmission within established mixed-status couples accounts for up to half of all new HIV infections among heterosexuals. Oral HIV pre-exposure prophylaxis (PrEP) is a highly effective prevention method, although underutilised among serodifferent couples. Moreover, there is a dearth of research on US HIV-serodifferent couples’ perspectives and use of PrEP, alone or in combination with other prevention methods. In this paper, we describe the study protocol for the Magnetic Couples Study, designed to fill critical knowledge gaps regarding HIV-serodifferent heterosexual couples’ …

Characteristics Of Patients Presenting With Covid-19 From Balochistan Province And Lessons Learnt, Abida Munir Badini, Aurangzeb Badini, Naeem M. Mengal, Kashmira Nanji

Department of Family Medicine

Objective: With the spread of COVID-19 in Pakistan, Balochistan province with its unique problems of lowest literacy rates in the country, limited resources and a flail health care system is reporting an increasing number of cases of COVID-19. This study discusses the epidemiological and clinical characteristics of COVID-19 patients from the Balochistan province.
Study design: Situation report Place and Duration of Study: The study was conducted in Balochistan province of Pakistan. The completion date for the study was April 30, 2020.
Methodology: The data was retrieved from the daily situation report from the Health Department, Government of Balochistan. Descriptive statistics …

Covid-19 In Hemodialysis Patients, Sonia Yaqub, Amna Hamid, Zarghoona Naeem

Section of Nephrology

No abstract provided.

Brain Abscess Caused By Lactococcus Lactis In A Young Male, Intisar Ahmed, Kashif Aziz, Hameed Tareen, Muhammad Arslan Ahmed

Section of Cardiology

Lactococcus lactis cremoris is one of the gram positive cocci, not known to be pathogenic in humans. We report a case of brain abscess due to lactococcus lactis in an adolescent. An 18-year male with congenitally corrected transposition of great arteries and dextrocardia was admitted with fever, headache and right-sided numbness. Magnetic resonance imaging revealed a well circumscribed irregular heterogeneous abnormal signal intensity lesion in left temporo-parietal lobe having central area of diffusion restriction and peripheral wall enhancement on post-contrast images. He underwent mini-craniotomy for abscess drainage. Pus culture revealed growth of lactococcus lactis. He was treated with ceftriaxone and …

Knowledge, Attitude And Practices On Contraceptives In Married Women Of Odisha, Smitha Moonjelly Vijayan Dr, Mamata Das Mrs, Kajal Patwal Ms, Prachi Parichita Ms, Chhaya Sharma Ms, Vidya Seervi Ms

Manipal Journal of Nursing and Health Sciences

Introduction: In developing countries, maternal and new-born mortality and morbidity rates can be reduced with apt contraceptive usage. This study aimed to assess the knowledge, attitude, and practices regarding contraception among married women

Methods: A descriptive study was conducted among 110 married women attending Obstetrics & Gynaecology OPD of AIIMS Bhubaneswar.

Result: The mean ± S.D. age of participants was 29.13±3.51 years. About half of the women (50.9%) had poor knowledge of contraception. More than half of women (65.17%) had a positive attitude on contraceptive use; however, only 24% of the subjects used a contraceptive, the most preferred contraceptive being …

Increasing Referrals To School Counselors By Integrating An Evidence-Based Program For Educators Identifying Adolescents At Risk For Suicide In A Rural High School, Wendy Holloway

Doctor of Nursing Practice Projects

Background: Addressing suicide in America's youth is imperative. Teachers play an essential role in identifying and intervening with adolescents experiencing psychological distress leading to suicide. Teachers and staff lack professional development addressing the identification of students in psychological distress.

Purpose: This project aimed to increase referrals to school counselors by integrating an evidence-based program for educators identifying adolescents at risk for suicide in a rural high school.

Design Method: This was a quantitative quality improvement project with a pre-/post-test design. Additionally, referrals to the school guidance counselors before implementing the program and after the completion of the program were …

Infectious Disease Screening In A Dedicated Primary Care Clinic For Children In Foster Care, Jill Mcleigh, Sarah Lairmore, Kimberly Stone, Rong Huang

Health Status, Outcomes, and Literacy and Healthcare Utilization

Children in foster care are considered at high risk for infectious diseases, and guidelines recommend screening for tuberculosis, hepatitis B and C, syphilis, gonorrhea and chlamydia. Little is known about the prevalence of infectious disease in children in foster care.

For questions about this study or others, please email [email protected]

childrens.com/fostercare

Jefferson Digital Commons Quarterly Report: April-June 2021, Kelsey Duinkerken, Msi, Larissa Gordon, Mslis, Med, Ma

Jefferson Digital Commons Reports

This quarterly report includes:

• Articles
• CREATE Day Capstone Projects
• Department of Surgery Resident Research Day
• Dissertations
• Grand Rounds and Lectures
• House Staff Quality Improvement and Patient Safety Conference
• JCPH Capstone Presentations
• Journals and Newsletters
• Know Diabetes by Heart Meetings
• MPH Course Projects
• Occupational Therapy Doctorate Capstones
• Posters and Conference Presentations:
• Promotional Video
• Scholarly Inquiry Abstracts
• What People are Saying About the Jefferson Digital Commons

Parent-Infant Bond: The Connection Between Parents And Infants In The Nicu, Megan Casselberry, Anita Fagotti, Ava Gambucci, Emma Sardinskas, Carly Scheiner

Collaborative Research and Evidence shared Among Therapists and Educators (CREATE Day)

Objectives

• Define the challenges of parent-infant relations in the neonatal intensive care unit (NICU) setting
• Discuss the role of occupational therapy in fostering parent-infant bonding in the NICU
• Interpret evidence-based interventions within the scope of occupational therapy practice to promote familial relations and social interactions amongst infants and parents

PICO Question
For infants in the NICU, what are evidence-based interventions within the scope of occupational therapy that increase parent-infant bonding?

Occupational Balance For A Better Mood: Occupational Therapy’S Role In Treating Excessive Technology Use In Youth, Emily Danilak, Jenna Higginbotham, Kara Leaman, Tarryn Slattery, Katie Virostek

Collaborative Research and Evidence shared Among Therapists and Educators (CREATE Day)

Objectives

• Understand the implications of excessive screen time on mental health and its pertinence to youth’s leisure time spent in the virtual environment.
• Identify the distinct role that occupational therapy has in addressing mental health needs in children.
• Analyze the current evidence for effective occupational therapy interventions targeting improved mental health in youth with unhealthy internet habits.

PICO Question
In children with excessive screen time, what interventions within the scope of occupational therapy practice improve mental health?

Promoting Social Participation For Young Individuals Following Concussion, Umara Iftikhar, Ann Claire Macalintal, Madeline Rea, Allizey Shields

Collaborative Research and Evidence shared Among Therapists and Educators (CREATE Day)

Objectives

1. Understand the relevance of anxiety and depression amongst young individuals following the onset of a concussion or post-concussive symptoms.
2. Recognize the distinct value of occupational therapy in promoting social skills to enhance relationships and mitigate feelings of isolation for persons with concussive symptoms.
3. Develop evidence-based interventions within the scope of occupational therapy for young individuals experiencing anxiety and depression following diagnosis of a concussion.

PICO Question
Amongst individuals, ages 13-25, experiencing symptoms of anxiety and depression following concussion, what interventions within the scope of Occupational Therapy will increase social participation?

Concussion And Class: Returning To College After A Mild Traumatic Brain Injury (Mtbi), Andrew Friedman, Gabrielle Khalifa, Rebecca Smith, Emily Strickberger

Collaborative Research and Evidence shared Among Therapists and Educators (CREATE Day)

Objectives

• Identify how concussion management to increase academic function falls within the scope of occupational therapy practice
• Describe effective concussion protocols and timelines as they apply to students’ recovery from mTBI and return to academics.
• Apply evidence based practice to treatment plans for patients post-concussion or mTBI injury returning to academics.

PICO Question
In college-aged adults that experienced a concussion, what are effective interventions within the scope of occupational therapy for return to university?

Delirium In The Acute Care Setting: Occupational Therapy’S Role In Delirium Management And Prevention, Regina Antoni, Grace Gaus, Kathleen Greaney, Marisa Ortiz-Brazak

Collaborative Research and Evidence shared Among Therapists and Educators (CREATE Day)

Objectives

• Explain delirium and its prevalence in the hospital setting
• Identify the role of occupational therapy in treatment of acute care patients with delirium
• Apply evidence-based interventions that address and prevent delirium in the acute care setting

PICO Question
What is the role of occupational therapy in delirium management for patients in the acute care setting?

Support For Me Assessment Of Substance Use Treatment And Recovery Services Current Infrastructure And Future Needs: Findings From The Support For Me Youth Survey (Condensed), Evelyn Ali Bs, Katie Rosingana Ba, Mary Lindsey Smith Phd

Substance Use Research & Evaluation

In 2019, Maine’s Department of Health & Human Services received a $2.1 million grant from the Centers for Medicare and Medicaid Services (CMS) SUPPORT Act, establishing the SUPPORT for ME initiative within the Office of MaineCare Services. The primary goal of this planning grant is to increase MaineCare providers’ capacity to deliver Substance Use Disorder (SUD) treatment and recovery services for Medicaid beneficiaries. In collaboration with Maine DHHS, the Cutler Institute conducted a survey for youth and young adults in Maine as part of a needs assessment for the SUPPORT for ME initative. The data collection goals of the survey …

Acute Urinary Retention: Should We Call It A Manifestation Of Appendicitis?, Sadaf Sheikh, Umair Javed, Muhammad Akbar Baig

Department of Emergency Medicine

Acute urinary retention (AUR) is a fairly common presentation in the elderly; but interesting to be noted in a healthy young individual as a manifestation of acute appendicitis. We present a case of a 32-year gentleman with decreased urine output with mild tenderness at the supra-pubic region; which was later on, shifted to the right iliac fossa. Computed tomography of the abdomen showed acute appendicitis. Emergency physicians are challenged to recognize the uncommon presentation of acute appendicitis and need to be reminded of this common complaint as a rare presentation of it. This case also stresses on the repeated abdominal …

Online Assessment In Undergraduate Medical Education: Challenges And Solutions From A Lmic University, Syeda Sadia Fatima, Romana Idrees, Kauser Jabeen, Saniya Sabzwari, Sadaf Khan

Department of Biological & Biomedical Sciences

Background and objectives: The Covid-19 pandemic has caused large-scale disruption in almost all educational programs across the world. Planning and rapid implementation of assessment through an online format presents the next set of novel challenges that must be addressed by academic administrations across the globe.
Methods: This cross-sectional study was conducted between March to August 2020 at the Aga Khan University Medical College. Two hundred medical students of year 1 and 2 participated in the study. We describe the planning, processes, and outcomes of online assessments using video communication platforms conducted at a private university in Pakistan. Standardized protocols were …

Using Economic Evaluation To Hasten Health Equity, Maria-Isabel Roldos, Nancy Breen

Publications and Research

Achieving health equity has proven elusive for two reasons. First, most research has focused on changing the behavior of individuals; however, policies that address socioeconomic factors or change the context to facilitate healthy decisions tend to be more effective. Second, health disparity science and evidence are not consistently used to guide policymakers, even those seeking health equity. In this perspective, we discuss economic evaluation tools that researchers can use to assist decision-makers in conducting research or evaluating policy: self-reported health-related quality-of-life surveys and cost–benefit analysis evaluations informed with the willingness to pay for research and analyses.

Alumni Journal - Volume 92, Number 2, Loma Linda University School Of Medicine

Alumni Journal, School of Medicine

Editorials
2 | From the Editor
4 | From the President
6 | From the Dean

News
8 | School of Medicine News
10 | Alumni News
12 | Students
14 | AIMS Report
16 | Department Reports: Radiology and Neurology

Graduation 2021
20 | Graduation Feature

Features
36 | By the Graduates
40 | Malamulo Heart Clinic
42 | The String that Draws Us to Our Alma Mater
44 | Adventist Medical Education
48 | Alumni Spotlight: Reginald R. Sherrill '77-A

In Memoriam
51 | Alumni Remembered

Nurses’ And Patients’ Perceptions Of The Availability Of Post-Hospital Instrumental Support As A Predictor Of 30- And 60-Day Acute Care Utilization, Beth E. Schultz

Theses and Dissertations

Social support is now part of the social determinants of health objective in Healthy People 2030. Positive social support improves health and well-being. Social support is concerned with people having the support they need within the community, including interacting and communicating with others on a regular basis. Instrumental support is a type of social support that is action oriented, involving one person directly assisting another person. A concept analysis of instrumental support was completed and revealed that the concept is well defined, but the terms used to describe it vary. Other terms in the research literature, most commonly “tangible support”, …

Successful Pivot Of A Community Exercise Program To Virtual During The Covid-19 Pandemic, Letracia Rose, James G Beckerman

Articles, Abstracts, and Reports

No abstract provided.

Does Feminine Gender Role Stress Moderate The Relationship Between Disordered Eating And Depression?, Paige Nichols

Masters Theses & Specialist Projects

The purpose of this investigation was to examine the moderating effect of feminine gender role stress on disordered eating behaviors and depression. It was hypothesized that feminine gender role stress would significantly moderate the relationship between disordered eating and depression, such that disordered eating behaviors would be more strongly associated with depression when FGRS total and subscale scores were high. These hypotheses were tested by surveying a sample of 334 university students (mean age = 20.54 years), all of whom were cisgender women. Participants completed self-report measures including the Eating Attitudes Test-26, Beck Depression Inventory, Feminine Gender Role Stress Scale, …