Medicine and Health Sciences Commons^™

2021-08-03_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated three times a week on Mondays, Wednesdays, and Fridays.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, …

2021-08-03_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled. It is updated Tuesday and Friday.
This report is provisional and subject to change. City of Detroit and Wayne County are reported separately. MDHHS began tracking probable cases April 5, 2020. FCI indicates federal correctional institute. MDOC indicates Michigan Department of Corrections. Diagnostic tests, including nucleic acid amplification/real-time polymerase chain reaction (NAAT/RT-PCR) and rapid virus antigen detection point of …

2021-08-03_Michiganoverview_Covidcounts, Michigan Department Of Health & Human Services

Michigan COVID-19 Confirmed Cases by Date of Onset Data

Data was downloaded as an Excel spreadsheet which appeared in the Public Use Datasets section under the Cumulative Data link of Michigan's Coronavirus webpage, under the url https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173---,00.html.

Cases are aggregated by the date of onset of COVID-19 symptoms, if known, otherwise by laboratory specimen date if known, otherwise by case referral date. Deaths are aggregated by the date of death if known, otherwise by the last date of a change to the case status.

2021-08-03_Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

Contains the tables Statewide Hospital Capacity Report for COVID-19, COVID-19 Metrics, Statewide Hospital Available PPE Tracking for COVID-19, as well as the tables PPE Days On Hand and Patient Census.

Comparison Of Constant Load Exercise Intensity For Verification Of Maximal Oxygen Uptake Following A Graded Exercise Test In Older Adults, Ian R. Villanueva, John C. Campbell, Serena M. Medina, Theresa M. Jorgensen, Shannon L. Wilson, Siddhartha S. Angadi, Glenn A. Gaesser, Jared M. Dickinson

All Faculty Scholarship for the College of Education and Professional Studies

Maximal oxygen uptake (VO₂max) declines with advancing age and is a predictor of morbidity and mortality risk. The purpose here was to assess the utility of constant load tests performed either above or below peak work rate obtained from a graded exercise test for verification of VO₂max in older adults. Twenty-two healthy older adults (9M, 13F, 67 ± 6 years, BMI: 26.3 ± 5.1 kg·m⁻²) participated in the study. Participants were asked to complete two experimental trials in a randomized, counterbalanced cross-over design. Both trials (cycle ergometer) consisted of (1) an identical graded exercise …

Fifteen-Year Trends In Incidence Of Cardiogenic Shock Hospitalization And In-Hospital Mortality In The United States., Mohammed Osman, Moinuddin Syed, Saikrishna Patibandla, Samian Sulaiman, Babikir Kheiri, Mahek K. Shah, Christopher Bianco, Sudarshan Balla, Brijesh Patel

Division of Cardiology Faculty Papers

BACKGROUND: There is a lack of contemporary data on cardiogenic shock (CS) in-hospital mortality trends.

METHODS AND RESULTS: Patients with CS admitted January 1, 2004 to December 31, 2018, were identified from the US National Inpatient Sample. We reported the crude and adjusted trends of in-hospital mortality among the overall population and selected subgroups. Among a total of 563 949 644 hospitalizations during the period from January 1, 2004, to December 30, 2018, 1 254 358 (0.2%) were attributed to CS. There has been a steady increase in hospitalizations attributed to CS from 122 per 100 000 hospitalizations in 2004 …

Integrated Onboarding: Synchronous Teaching To Prepare Learners For Successful Orientation, Nicole Wiswesser Msn, Rn, Cmsrn, Kathleen L. Chenard Msn, Rnc-Ob, Elizabeth A. Posasinski

Department of Education

No abstract provided.

Resilience And Its Associated Factors In Head And Neck Cancer Patients In Pakistan: An Analytical Cross-Sectional Study, Nida Zahid, Wajeeha Zahid, Wardah Khalid, Syed Iqbal Azam, Mubasher Ikram, Aneesa Hassan, Haissan Iftikhar, Shireen Shehzad Bhamani, Adnan Jabbar, Shabbir Akhtar, Moghira Siddiqui, Mohammad Sohail Awan, Nargis Asad, Khabir Ahmad

Department of Surgery Docs

Introduction: The study aimed to assess resilience and its associated factors in head and neck cancer patients, post-treatment in a low middle income country (LMIC) such as Pakistan.
Methods: An analytical cross-sectional study was conducted from November 2019 to May 2020 among head and neck cancer patients aged at least 18 years at the largest private tertiary care hospital, in Karachi, Pakistan. Information regarding their resilience scores was collected through Wagnild and Young's Resilience scale that comprises of 14 items (RS-14). Moreover, depression and anxiety were also assessed via Hospital Anxiety and Depression Scale (HADS) and social support was assessed …

Graduate Commencement, Philadelphia (2021), Philadelphia College Of Osteopathic Medicine

Commencements

Philadelphia Campus Graduate Commencement program, Class of 2021. Degrees include Doctor of Psychology in Clinical Psychology, Doctor of Psychology in Educational Psychology, Doctor of Psychology in School Psychology, Educational Specialist in School Psychology, Master of Science in School Psychology, Master of Science in Counseling and Clinical Health Psychology, Master of Science in Mental Health Counseling, Master of Science in Organizational Development and Leadership, Master of Science in Clinical Psychology, Master of Science in Forensic Medicine, Master of Science in Biomedical Sciences, and Master of Science in Health Sciences – Physician Assistant Studies.

Commencement Speaker: Robert F. Cuzzolino, Ed.D., Vice President …

Segmental Absence Of Intestinal Musculature In A Child With Type Iv Ehlers-Danlos Syndrome, Nicole Zeky, Celia Short, Brent Keith, Randall Craver, Jessica A. Zagory

School of Medicine Faculty Publications

Patients with vascular Ehlers-Danlos syndrome (vEDS) have a defect in the formation of type III collagen. This defect puts patients at risk of vascular rupture, uterine rupture, and bowel perforations. The segmental absence of intestinal musculature is a rare histopathologic finding, wherein there is a lack of a muscularis propria layer in the intestinal wall. Although typically documented in the literature in neonates or adults, it can be seen in children of other ages. This is a case report of a patient who exhibits both rare entities, which has not been described in the literature to date.

Supporting Health Literacy In Adolescent Populations: Distinguishing Pedagogies For Sun Safety Education In Schools, Donna Barwood

Research outputs 2014 to 2021

Purpose: The aim of this paper is to distinguish pedagogies supporting critical health literacy development in adolescent populations. Specifically, for sun safety education in schools.

Design/methodology/approach: The paper draws on an exploratory intrinsic case study design to qualitatively examine the learning conditions that Pre-Service Teachers' (PsTs) mobilise to advance Health Literary (HL) in learning activities.

Findings: This paper presents data that shows the different ways thirty Pre-Service Teachers (PsTs) in Western Australia conceptualise HL in sun safety education for Year 7 students (12–13 years old). Examination of three consecutive lesson plans categorised learning activities (n = 444) according to HL …

Invader Removal Triggers Competitive Release In A Threatened Avian Predator, J. David Wiens, Katie M. Dugger, J. Mark Higley, Damon B. Lesmeister, Alan B. Franklin, Keith A. Hamm, Gary C. White, Krista E. Dilione, David C. Simon, Robin R. Bown, Peter C. Carlson, Charles B. Yackulic, James D. Nichols, James E. Hines, Raymond J. Davis, David W. Lamphear, Christopher Mccafferty, Trent L. Mcdonald, Stan G. Sovern

United States Department of Agriculture Wildlife Services: Staff Publications

Changes in the distribution and abundance of invasive species can have far-reaching ecological consequences. Programs to control invaders are common but gauging the effectiveness of such programs using carefully controlled, large-scale field experiments is rare, especially at higher trophic levels. Experimental manipulations coupled with long-term demographic monitoring can reveal the mechanistic underpinnings of interspecific competition among apex predators and suggest mitigation options for invasive species. We used a large-scale before-after control-impact removal experiment to investigate the effects of an invasive competitor, the barred owl (Strix varia), on the population dynamics of an iconic old-forest native species, the northern spotted owl …

Associations Between Fasting Duration, Timing Of First And Last Meal, And Cardiometabolic Endpoints In The National Health And Nutrition Examination Survey, Michael David Wirth, Longgang Zhao, Gabrielle Turner-Mcgrievy, Andrew Ortaglia

Faculty Publications

Background: Research indicates potential cardiometabolic benefits of energy consumption earlier in the day. This study examined the association between fasting duration, timing of first and last meals, and cardiometabolic endpoints using data from the National Health and Nutrition Examination Survey (NHANES). Methods: Cross-sectional data from NHANES (2005–2016) were utilized. Diet was obtained from one to two 24-h dietary recalls to characterize nighttime fasting duration and timing of first and last meal. Blood samples were obtained for characterization of C-reactive protein (CRP); glycosylated hemoglobin (HbA1c %); insulin; glucose; and high-density lipoprotein (HDL), low-density lipoprotein (LDL), and total cholesterol. Survey design procedures …

Family-Based Obesity Prevention Interventions Among Hispanic Children And Families: A Scoping Review, Erica G Soltero, Armando Peña, Veronica Gonzalez, Edith Hernandez, Guisela Mackey, Chishinga Callender, Jayna M Dave, Debbe Thompson

Children’s Nutrition Research Center Staff Publications

This scoping review examined intervention and sample characteristics of family-based obesity prevention interventions among Hispanic youth. This review also examined the degree to which existing interventions were culturally-adapted, acknowledged social determinants of health (SDoH), and collaborated with community stakeholders. A comprehensive search across Medline Ovid, Embase, Scopus, PsycInfo, and Pubmed was used to identify 13 studies primarily based in the U.S. (92.3%). Data was extracted by two independent reviewers. Most used a randomized control trial design (69.2%), a behavior change theory (84.6%), and reported moderate to high (≥70%) retention (69.2%). Studies targeted improvements in physical activity (69.2%) and fruit and …

A Machine Learning Case-Control Classifier For Schizophrenia Based On Dna Methylation In Blood, Chathura J Gunasekara, Eilis Hannon, Harry Mackay, Cristian Coarfa, Andrew Mcquillin, David St Clair, Jonathan Mill, Robert A Waterland

Children’s Nutrition Research Center Staff Publications

Epigenetic dysregulation is thought to contribute to the etiology of schizophrenia (SZ), but the cell type-specificity of DNA methylation makes population-based epigenetic studies of SZ challenging. To train an SZ case–control classifier based on DNA methylation in blood, therefore, we focused on human genomic regions of systemic interindividual epigenetic variation (CoRSIVs), a subset of which are represented on the Illumina Human Methylation 450K (HM450) array. HM450 DNA methylation data on whole blood of 414 SZ cases and 433 non-psychiatric controls were used as training data for a classification algorithm with built-in feature selection, sparse partial least squares discriminate analysis (SPLS-DA); …

Psychological Impact Of Covid-19 And Lock Down Measures: An Online Cross-Sectional Multicounty Study On Asian University Students, Karuthan Chinna, Sheela Sundarasen, Heba Bakr Khoshaim, Kamilah Kamaludin, Mohammad Nurunnabi, Gul Mohammad Baloch, Syed Far Abid Hossain, Areej Sukayt, Nevi Dalina, Zahid Memon

Centre of Excellence in Women and Child Health

The COVID-19 pandemic and the lockdown measures have taken a toll on every level of the society, worldwide. This study examines their psychological impact on university students in Asia. A cross-sectional online survey was conducted between April and May 2020 in Malaysia, Saudi Arabia, Pakistan, Bangladesh, China, India and Indonesia. The Zung's self-rating anxiety scale (SAS) and questions on adaptive and maladaptive coping strategies were used in this study. A total of 3,679 students from the seven countries participated in this study. Overall, 21.9% and 13.7% of the students in this study experienced mild to moderate and severe to extreme …

Pathophysiology Of Delayed Cerebral Ischemia After Subarachnoid Hemorrhage: A Review., William S. Dodd, Dimitri Laurent, Aaron S. Dumont, David M. Hasan, Pascal M. Jabbour, Robert M. Starke, Koji Hosaka, Adam J. Polifka, Brian L. Hoh, Nohra Chalouhi

Department of Neurosurgery Faculty Papers

Delayed cerebral ischemia is a major predictor of poor outcomes in patients who suffer subarachnoid hemorrhage. Treatment options are limited and often ineffective despite many years of investigation and clinical trials. Modern advances in basic science have produced a much more complex, multifactorial framework in which delayed cerebral ischemia is better understood and novel treatments can be developed. Leveraging this knowledge to improve outcomes, however, depends on a holistic understanding of the disease process. We conducted a review of the literature to analyze the current state of investigation into delayed cerebral ischemia with emphasis on the major themes that have …

Simultaneous Ck2/Tnik/Dyrk1 Inhibition By 108600 Suppresses Triple Negative Breast Cancer Stem Cells And Chemotherapy-Resistant Disease., Katsutoshi Sato, Amol A. Padgaonkar, Stacey J. Baker, Stephen C. Cosenza, Olga Rechkoblit, D.R.C. Venkata Subbaiah, Josep Domingo-Domenech, Alison Bartkowski, Elisa R. Port, Aneel K. Aggarwal, M. V. Ramana Reddy, Hanna Y. Irie, E. Premkumar Reddy

Department of Medical Oncology Faculty Papers

Triple negative breast cancer (TNBC) remains challenging because of heterogeneous responses to chemotherapy. Incomplete response is associated with a greater risk of metastatic progression. Therefore, treatments that target chemotherapy-resistant TNBC and enhance chemosensitivity would improve outcomes for these high-risk patients. Breast cancer stem cell-like cells (BCSCs) have been proposed to represent a chemotherapy-resistant subpopulation responsible for tumor initiation, progression and metastases. Targeting this population could lead to improved TNBC disease control. Here, we describe a novel multi-kinase inhibitor, 108600, that targets the TNBC BCSC population. 108600 treatment suppresses growth, colony and mammosphere forming capacity of BCSCs and induces G2M arrest …

Perceptions And Experiences Of Healthcare Providers During Covid-19 Pandemic In Karachi, Pakistan: An Exploratory Qualitative Study, Anam Shahil Feroz, Nousheen Pradhan, Zarak Hussain Ahmed, Mashal Murad Shah, Nargis Asad, Sarah Saleem, Sameen Siddiqi

Community Health Sciences

Objective: To explore healthcare provider's perspectives and experiences of the barriers and facilitators to treat and manage COVID-19 cases.
Design and setting: We conducted an exploratory qualitative study using a purposive sampling approach, at a private tertiary care teaching hospital in Karachi, Pakistan. Study data were analysed manually using the conventional content analysis technique.
Participants: Key-informant interviews (KIIs) were conducted with senior management and hospital leadership and in-depth interviews (IDIs) were conducted with front-line healthcare providers.
Results: A total of 31 interviews (KIIs=19; IDIs=12) were conducted, between April and May 2020. Three overarching themes emerged. The first was 'challenges faced …

A Standardized Orientation For Newly-Licensed Nurses And Preceptors In The Emergency Department, Judith Baker Bsn, Rn, Michelle Greis Bsn, Rn, Cen, Reza Armaghan Msn, Rn, Cen, Phrn

Department of Emergency Medicine

No abstract provided.

Targeted Provider Education And Pre-Visit Planning Increase Rates Of Formal Depression Screening In Childhood-Onset Sle., Evan Mulvihill, Rebecca Furru, Alana Goldstein-Leever, Kyla Driest, Stephanie Lemle, Darby Macdonald, Emily Frost, Vidya Sivaraman

Department of Pediatrics Faculty Papers

BACKGROUND: Despite being at high risk for depression, patients with childhood-onset systemic lupus erythematosus (c-SLE) are infrequently and inconsistently screened for depression by their pediatric rheumatologists. We aimed to systematically increase rates of formal depression screening for c-SLE patients in an academic Pediatric Rheumatology clinic.

METHODS: Our multi-disciplinary quality improvement (QI) team used electronic health record (EHR) documentation to retroactively calculate baseline rates of documented depression screening using the Patient Health Questionnaire-9 (PHQ-9). We then engaged key stakeholders to develop a clinical workflow for formal depression screening in the clinic. We also provided education to providers regarding mental health disorders …

Polyploid Giant Cancer Cells And Ovarian Cancer: New Insights Into Mitotic Regulators And Polyploidy†, Joanne S Richards, Nicholes R Candelaria, Rainer B Lanz

Faculty, Staff and Students Publications

Current first-line treatment of patients with high-grade serous ovarian cancer (HGSOC) involves the use of cytotoxic drugs that frequently lead to recurrent tumors exhibiting increased resistance to the drugs and poor patient survival. Strong evidence is accumulating to show that HGSOC tumors and cell lines contain a subset of cells called polyploidy giant cancer cells (PGCCs) that act as stem-like, self-renewing cells. These PGCCs appear to play a key role in tumor progression by generating drug-resistant progeny produced, in part, as a consequence of utilizing a modified form of mitosis known as endoreplication. Thus, developing drugs to target PGCCs and …

Catastrophic Antiphospholipid Syndrome (Caps) – A Case Report, Belisha Dmello, Latha T. Bhat, Barkur Ananthakrishna Shastry

Manipal Journal of Nursing and Health Sciences

Catastrophic antiphospholipid syndrome is a rare disease with positive antiphospholipid antibodies that progresses to a life-threatening condition resulting in multiple organ dysfunction and thromboses. Here is a 19-year young woman who presented to the emergency room in a haemodynamically unstable condition requiring immediate mechanical ventilator support. She had involvement of the disease in the respiratory, cardiovascular, renal, and central nervous systems. She also developed gangrene of the left toes for which amputation was done. She was successfully treated with Dexamethasone Cyclophosphamide Pulse (DCP) therapy. The collaborative care by the health team members in the intensive care unit was successful in …

Mayer Rokitansky Kuster Hauser Syndrome: A Case Of Mullerian Agenesis, Anu Baby, Simi Kurian, Rani Jose

Manipal Journal of Nursing and Health Sciences

Developmental anomalies of the Mullerian duct are one of the fascinating congenital disorders encountered in which Mayer Rokitansky Kuster Hauser syndrome (MRKH) is one of the wide variety of malformations. The most common presentation in MRKH syndrome is primary amenorrhea with normal development of secondary sexual characteristics and normal female karyotype (46, XX). The ovaries and fallopian tubes are usually functional, but the uterus and upper two-third vagina are either underdeveloped or absent. MRKH syndrome can either be an isolated utero-vaginal aplasia (Type I) or associated with extragenital anomalies (Type II). A case of Type I MRKH syndrome is reported …

Assessment And Oral Care: An Essential Nursing Activity For Patients Receiving Cancer Treatment, Radhika R. Pai, Ravikiran Ongole, Sourjya Banerjee

Manipal Journal of Nursing and Health Sciences

Head and neck radiation therapy and chemoradiation are inherently associated with severe oral complications such as oral mucositis, infection, and functional issues of the oral cavity, significantly affecting the quality of oral cavity health in cancer patients. Oral care in cancer patients is a vital part of nursing care but can be seen as a most neglected job, along with other duties or a tedious task to undertake. Recognizing the effect of cancer treatment and delivery of oral care as per the specific guidelines to cancer patients is not well known, and it is not clear. Literature review reports that …

Effect Of Empowered Female Labour Companion On Anxiety, Birth Outcome, And Maternal Satisfaction Among Primiparturients, Jisha C, Sreeja G. Pillai

Manipal Journal of Nursing and Health Sciences

Labour companionship is a core element of care for improving maternal and infant health outcomes and providing respectful maternity care for a positive childbirth experience.Objective: Evaluate the effect of empowered female labour companion on anxiety, birth outcome and maternal satisfaction among primiparturients. Methods: Quantitative approach with Quasi-experimental non-equivalent control group post-test only design was used to collect data from 34 (Experimental group-17, Control group-17) primiparturients selected by consecutive sampling technique from the labour room of Govt. Medical College Hospital, Kannur. Data was collected using an interview schedule, labour specific anxiety scale, maternal satisfaction scale and birth outcome observation record, and …

Indian Healthcare System: Reflections Of Swedish Nursing Students, Elisabeth Mangrio

Manipal Journal of Nursing and Health Sciences

Internationalization within nursing programs is essential to provide nurses with cultural competence and for nursing students to gain an international perspective. It has also been shown to be effective to gain a cultural understanding. This paper aims to illuminate and explain the experiences that Swedish nursing students had while they engaged in clinical training during an exchange program in India and to provide a comparison between the health service in both countries. Nursing students from Sweden did a four-week clinical placement within the primary healthcare in India in 2020. During the clinical placement, which consisted of a variety of healthcare …

Menstrual Pattern, Practices, Problems And Its Impact On Activities During Menstruation Among Adolescent Girls At Chennai, India, Prema Janardan, R Sudha

Manipal Journal of Nursing and Health Sciences

A descriptive correlational study was undertaken to assess the menstrual pattern, practices, problems, and its impact on activities during menstruation among adolescent girls. Total of 123 adolescent girls were selected by using the non-probability convenience sampling technique. Demographic proforma and self report checklist was used to collect the data.The results revealed that the majority of the adolescent girls had a partially abnormal menstrual pattern and all used sanitary napkins as absorbent. The majority had reported some problems during menstruation with dysmenorrhea being the predominant one and had reported some impact on the activities during menstruation with special reference to absenteeism …

Effectiveness Of Mirror Therapy On Upper And Lower Limb Function Among Stroke Patients With Hemiparesis, Silpa C

Manipal Journal of Nursing and Health Sciences

Introduction: The upper and lower limb function impairment remains an undesirable consequence followed by a stroke that increases activity limitation. Objective: To find the effectiveness of mirror therapy on upper and lower limb function among stroke patients with hemiparesis admitted at Govt Medical College, Kannur. Methods: Quasi experimental, non-equivalent control group pre-test post-test research design was used among 24 stroke patients with hemiparesis who met inclusion criteria by using consecutive sampling technique and allotted to both experimental (n=12) and control group (n=12). Mirror therapy was administered to the experimental group daily for two weeks. A semi-structured interview schedule and Fugl-Meyer …

Effectiveness Of Video-Assisted Teaching On Awareness (Knowledge And Attitude) Towards Mental Illness Among Public, Vinisha Almeida, Nanda Kumar Paniyadi, Asha K. Nayak

Manipal Journal of Nursing and Health Sciences

Introduction: Knowledge and attitude of mental illness affect behaviour tremendously. The attitude of people towards mental health problems are negative, condemned, ignorant, and apprehensive. Objectives: To assess the effectiveness of video-assisted teaching (VAT) on knowledge and attitude of the public towards mental illness. Methods: A quantitative, pre-experimental one-group pre-test post-test design was used among 80 people using a judgmental sampling technique. For data collection, a knowledge questionnaire and an attitude scale were developed. An appropriate VAT was developed that was administered as an intervention. The intervention was done after four weeks and the effectiveness of the program was assessed by …