Medicine and Health Sciences Commons^™

Decreasing Use Of Primary Care: A Repeated Cross-Sectional Study Of Meps 2007-2017., Michael E Johansen, Joshua D Niforatos

Ambulatory and Primary Care Articles

We sought to describe the proportion of patients in contact with a primary care physician, as well as the total number of primary care contacts over a 2-year period, using the 2002-2017 Medical Expenditure Panel Survey. The rate of any contact with a primary care physician for patients in the population decreased by 2.5% over the study period (adjusted odds ratio [aOR] = 0.99 per panel, 95% CI, 0.98-0.99;

Brooke-Spiegler Syndrome: Familial Cylindromatosis, A Rare Variant Of A Rare Familial Syndrome., Harsh Patel, William Naber, Austin Cusick, Craig Oser

Ambulatory and Primary Care Articles

Brooke-Spiegler Syndrome (BSS) is a rare autosomal dominant familial disorder resulting in dermatologic neoplasms of copious nodular appendages. Here, we report a case of Familial Cylindromatosis (FC), a subtype of BSS, in a patient with the largest cylindroma of 7.4 × 5.6 × 3.8 cm on the scalp. The patient had undiagnosed cylindromas growing for 36 years at presentation; however, he did not seek out healthcare evaluation. Excision and pathologic investigation of three large masses from different body sites determined a shared phenotype of cylindromas. Subsequent evaluation of the patient's son separately, after primary patient excision, confirmed cylindroma development as …

Impact Of Behavioral Side Effects On The Management Of Parkinson Patients Treated With Dopamine Agonists., Mohammad Edrees Mohammad, Joaquin A Vizcarra, Xiomara Garcia, Shnehal Patel, Adam Margolius, Xin Xin Yu, Hubert H Fernandez

Neuroscience Articles

Dopamine agonists are one of the main stay of treatment option for Parkinson disease (PD). Side effects that develop from their use are generally categorized into behavioral and non-behavioral. Behavioral side effects include: impulse control behavior disorder (ICD), psychosis and cognitive impairment. Non-behavioral side effects include: nausea/vomiting, "sleep attacks", leg swelling, weight gain and orthostasis. The aim of this study is to evaluate the clinicians' response to PD patients who developed behavioral side effects from dopamine agonists, in comparison to those patients who developed only non-behavioral side effects. We performed a retrospective chart review of all patients diagnosed with …

Multiplex Fluorescence Quantitative Pcr For The Detection Of Eight Bacterial Pathogens Ofporcine Respiratory Disease Complex (Prdc), Jingbo Wu, Wenjin Nan, Jiangqiang Huang, Guoliang Peng, Honghui Hu

Turkish Journal of Veterinary & Animal Sciences

As rapid and reliable tools for diagnosis of porcine respiratory disease complex (PRDC) bacterial pathogens are getting more important over time, we established a new multiplex fluorescence quantitative polymerase chain reaction (mFQ-PCR) system with a similar symptom. Our results showed that the system could accurately and simultaneously detect 8 pathogens within 1.5 h. The detection limits were 2-5 standard DNA copies. The correlation coefficient of the standard curve was more than 0.998, with a well dynamic range from 101 to 109, and the intra- and intervariation coefficients (CVs) were less than 2.06%. After setting the positive threshold of Ct value, …

Chemical Castration Using An Intratesticular Injection Of Mannitol: A Preliminary Studyin A Rat Model, Mohammad-Ali Maadi, Mehdi Behfar, Amir Rasaei, Ali Shalizar-Jalali, Gholamreza Najafi, Vahid Mohammadi

Turkish Journal of Veterinary & Animal Sciences

This study was aimed to evaluated chemical sterilization using an intra-testicular injection of mannitol 20% in rats. Fifty male Wistar rats were divided into five groups, including 1) intact, 2) surgical castration and, 3 to 5) intra-testicular injections of normal saline, hypertonic saline, and mannitol, respectively. The baseline testosterone levels were measured. Surgical castration was performed in group 2. Intra-testicular injections were performed in groups 3, 4, and 5. On day 60, the testosterone level was evaluated. Then, sperm count, viability, motility, morphological abnormalities and DNA damage were studied. Gonadosomatic index was recorded on day 60. Serum testosterone level was …

Comparison Of Feed Value Of Amaranthus Powellii Willd. Forage To Some Roughagefeeds, Gökhan Fi̇li̇k, Ayşe Gül Fi̇li̇k

Turkish Journal of Veterinary & Animal Sciences

The aim of this study was to compare the chemical composition, in vitro digestibility, protein and energy value, roughage value of Amaranthus powellii Willd. forage to the most commonly used alfalfa hay and wheat straw in ruminant nutrition. Amaranthus powellii Willd. forage has the potential to be a third quality roughage according to its relative feed value assessment of 104.55 ± 0.67. In addition, the relative forage quality assessment developed for feeding dairy cattle was 97.73 ± 0.05 for Amaranthus powellii Willd. forage, which had a higher the relative forage quality value than alfalfa hay and wheat straw, and it …

Residue Depletion Of Sarafloxacin In Black-Bone Silky Fowl Tissues After Oraladministration, Bao-Tao Liu, Shi-Kai Sun, Li Chen, Junjun Yu

Turkish Journal of Veterinary & Animal Sciences

In this study, the residue depletion of sarafloxacin in black-bone silky fowl (BSF) was studied after oral doses of sarafloxacin (10 mg/kg BW for 7 consecutive days). Muscle and liver tissues were collected at differentwithdrawal periods and determined by HPLC-MS/ MS method. The limit of detection for sarafloxacin was 1.0 μg/kg, and the recoveries from blank fortified samples were 93.53%~108.47% with coefficients of variation less than 9.28%. At first day after ending sarafloxacin treatment, the mean concentrations of sarafloxacin in muscle and liver were 366.88 ± 129.51 and 120.35 ± 46.86 μg/kg, respectively, higher than their maximum residue limits (10 …

Effect Of Vanadium (Iv) Chloride Supplementation On Appetite-Related Hormone Levels Inrats With Experimentally Induced Diabetes, Tünay Kontaş Aşkar, Adnan Adi̇l Hi̇şmi̇oğullari, Olga Büyükleblebi̇ci̇, Hati̇ce Nur Er Sarikaya

Turkish Journal of Veterinary & Animal Sciences

Vanadium is one of the essential trace elements for mammals, which has important functions in the metabolism of carbohydrates. There is limited data about the effects of vanadium (IV) chloride supplementation on appetite-related hormones in literature. Our target was to analyse the impacts of vanadium supplementation on appetite-related hormone (leptin, nesfatin-1 and apelin) levels in rats with experimentally induced diabetes. Twenty eight male Sprague-Dawley albino rats were used in this study. After formation of diabetes, 0.3 mg/mL of vanadium was added to drinking water of rats for four weeks. A substantial increment was found in serum glucose (p < 0.001), HbA1c (p < 0.001), HOMA-IR (p < 0.01), and leptin (p < 0.001) levels and a significant decrease in insulin, apelin and nesfatin-1 concentrations in diabetic rats. Moreover, blood glucose, HbA1c, HOMA-IR, and leptin levels decreased in diabetic + vanadium group, but nesfatin-1 (1.74 ± 0.94 ng/mL), apelin (1.74 ± 0.94 ng/mL), and insulin concentrations were found higher compared with the diabetic group. As a result of this study, vanadium has increased the levels of circulating nesfatin-1 and apelin levels in diabetic rats while decreasing blood glucose and leptin concentrations. But further studies are required to determine the blood glucose lowering effects of vanadium and its relationship with appetite related hormones in diabet.

Detection Of Varroa Mites From Honey Bee Hives By Smart Technology Var-Gor: A Hivemonitoring And Image Processing Device, Sedat Sevi̇n, Hi̇dayet Tutun, Seli̇me Mutlu

Turkish Journal of Veterinary & Animal Sciences

The major honey bee parasite Varroa destructor reduces hive vitality and honey yields by preventing growth of heathy bees and causes drastic loss in apiculture. Therefore, mite infestation in honey bee needs to be constantly controlled by beekeepers. To minimize this loss, a system called Var-Gor has been developed with the aim of controlling Varroa mite infestation before/just after entering the hive instead of the late period. Var-Gor is a hive entrance attachable device box consist of bee passage tunnels (width: 25 mm, height: 15 mm, and depth: 50 mm), autofocus detection camera combined with interface (process sensor: IV-HG10) and …

Identification Of Micrornas In The Follicular And Luteal Tissues Of Holstein-Friesian Cows, Selçuk Özdemi̇r, Seli̇m Çomakli

Turkish Journal of Veterinary & Animal Sciences

MicroRNAs (miRNAs) regulate many physiological pathways, including development, cell differentiation, immune response as well as diseases by post-transcriptional processes. However, information is limited regarding the biological roles of miRNAs in the development of the follicular and luteal tissues in cows. The main aim of the present study was to identify miRNAs that are expressed in the follicular and luteal tissues of cows. We used a comparative RNA sequencing method to identify miRNA candidates that might play key roles in the follicular and luteal phases of Holstein cows. Nine miRNAs were expressed at a high ratio: 8 in the follicular tissue …

The Modern Use Of The Extended Humeral Head (Cuff Tear Arthropathy) Hemiarthroplasty., Tyler J Smith, Sarav S Shah, Justin W Peterson, Glen Ross

Orthopedic Surgery Resident Research

Today, the treatment of osteoarthritis in the rotator cuff-deficient population is largely dominated by reverse shoulder arthroplasty (RSA). Despite the popularity of and increased familiarity with this procedure, the complication rate of RSA remains significant. An extended humeral head hemiarthroplasty may provide a less invasive alternative for select patients with cuff tear arthropathy (CTA) and preserved glenohumeral active elevation. With the indications for reverse arthroplasty expanding to younger patients, there are concerns about the longevity of this implant, as well as the associated revision burden. In the setting of failed RSA, the bone stock available for glenosphere baseplate fixation can …

Incorporating Psychological Trauma Into Adhd Differentials: A Pilot Study Of Primary Care Providers' Perspectives, Amber Nipper

PsyD Program in Clinical Psychology Doctoral Dissertations (Seattle)

According to the American Academy of Pediatrics (AAP, n.d.), 40% to 50% of individuals seeking mental health services terminate prematurely due to lack of access, lack of transportation, financial constraints, child mental health professional shortages, and stigma related to mental health. These barriers contribute to primary care providers assessing and managing mental health concerns at increasing rates, particularly symptoms consistent with attention deficit/hyperactivity disorder (ADHD). ADHD is a neurobiological disorder beginning in childhood that is defined as “a persistent pattern of inattention and/or hyperactivity-impulsivity that interferes with functioning or development” (American Psychiatric Association [APA], 2013, p. 59). Current literature shows …

Digest Of The Philadelphia College Of Osteopathic Medicine (2021 No. 1), Philadelphia College Of Osteopathic Medicine

PCOM Digest 2020s

The 2021 No. 1 issue of the Digest of the Philadelphia College of Osteopathic Medicineincludes the following articles:

• Updates
• Institutional Heritage: Founders’ Day
• Meta L. Christy, DO: The First African American Osteopathic Physician
• Standing on Her Shoulders: Celebrating Meta L. Christy, DO, and African American Alumnae Trailblazers
• Class Notes

Preoperative Education In Lumbar Fusion Patients: Impact On Postoperative Disability Perception, Megan Curtis

Doctor of Nursing Practice Scholarly Projects

Background/Review of Literature: A lumbar fusion is a complex surgical intervention with many postoperative guidelines and restrictions. Preparing patients with surgery specific education has shown to decrease their sense of disability and postoperative pain in other surgical specialties, but a disparity exists in spinal surgery.
Purpose: To examine the effect of a preoperative education class for lumbar fusion patients on their perceived level of disability, the number of patient phone calls made to the neurosurgery office, the number of postoperative emergency room (ER) visits, and the number of hospital readmissions after surgery.
Methods: A quality improvement project utilizing a quantitative …

Mcnair Scholars Research Journal 2021, Calyha Brown, Caroline Carter, Kalvry Cooper, Perla Rodriguez, Huu Trung Tran, Jose A. Cortes, Orion Wynne, Johnathan Alexander Andres, Joshua Perez, Allison Fenske, Chasidah Fried, Giles Fitzwilliams

McNair Scholars Research Journal-Archive

No abstract provided.

Female And Male-Controlled Livestock Holdings Impact Pastoralist Food Security And Women’S Dietary Diversity, Henriette Gitungwa, Christopher Gustafson, E.Y. Jimenez, E. Wesley F. Peterson, M. Mwanzalila, Asha Makweta, E. Komba, R.R. Kazwala, J.A.K. Mazet, Elizabeth Vanwormer

School of Veterinary and Biomedical Sciences: Faculty Publications

Background: Food insecurity is a global problem that requires a One Health approach. As many households in low- and middle-income nations rely on crops and livestock that they produce to meet their household’s needs, food security and nutrition are closely linked to the health of animals and the environment. Resources controlled by women are more often allocated to uses that benefit the entire household, such as food, health, and educating children, than men’s resources. However, studies of gender control of resources among pastoralist societies are scant. We examined the effect of female and male control of livestock resources on food …

Life In Metropolitan Nebraskan Communities: 2021 Nebraska Metro Poll Results, Rebecca J. Vogt, Heather Akin, Cheryl A. Burkhart-Kriesel, Bradley Lubben, L. J. Mcelravy, Timothy Meyer, Steven A. Schulz

Rural Futures Institute: Publications

By many different measures, metropolitan Nebraskans are positive about their community. Most metropolitan Nebraskans rate their community favorably on its social dimensions. Overall, respondents rate their communities as friendly, trusting and supportive. Most metropolitan Nebraskans say it would be difficult to leave their community.

Most metropolitan Nebraskans have a positive attachment to their community. Most metropolitan Nebraskans agree that they can get what they need in their community, the community helps them fulfill their needs, they feel like a member of their community, they belong in their community, they have a good bond with others in their community and feel …

Responses Of Predatory Myxobacteria To Prey Signaling Molecules & Features Of A Pseudomonas Prey Avoiding Predation, Shukria Akbar

Electronic Theses and Dissertations

Gram-negative unicellular myxobacteria, along with their multicellular lifestyle andbiologically active specialized metabolites, are known for the predatory interactions with Gram-negative/ Gram-positive bacteria and fungi. Although myxobacterial predation range have been exploited extensively, little is known about the prey associated molecules contributing to myxobacterial predator-prey dynamics. By employing transcriptomics and untargeted metabolomics approaches, we demonstrate two structurally distinct classes of signaling molecules from Gram-negative bacterial prey elicit significant omics responses from myxobacteria, Myxococcus xanthus and Cystobacter ferrugineus. An overlapping and general response to acylhomoserine lactones, whereas a distinctive response to a quinolone signaling molecule is observed from both myxobacteria. Similarly, by …

Prevalence Of Hearing Loss In College Students In The United States: A Meta-Analysis, Ashley Barton

Electronic Theses and Dissertations

Purpose: Hearing loss among college students, specifically noise-induced hearing loss (NIHL), appears to be increasing. This may be particularly challenging for this population as college students are required to listen to lectures in classrooms that may have sub-optimal listening environments. Therefore, the purpose of the current study was (1) to examine the prevalence of hearing loss in college students and (2) to emphasize the importance of detecting hearing loss at 6,000 Hz.Method: A meta-analysis was conducted using the PRISMA model. The literature search yielded 8 studies (1,950 subjects) that tested hearing loss using an audiogram and Distortion Product Otoacoustic Emissions …

ผลของการได้รับคาเฟอีนระหว่างการวิ่ง ต่อสมรรถภาพความอดทนในนักวิ่งฮาล์ฟมาราธอนชาย, นัฐพงษ์ สีพิกา

Chulalongkorn University Theses and Dissertations (Chula ETD)

การศึกษาวิจัยครั้งนี้มีวัตถุประสงค์ เพื่อศึกษาผลของการได้รับคาเฟอีนต่อสมรรถภาพความอดทน การตอบสนองของสารชีวเคมีในร่างกาย และอาการของระบบทางเดินอาหารในนักกีฬาวิ่งฮาล์ฟมาราธอนชาย นักกีฬาวิ่งฮาล์ฟมาราธอนชายที่ฝึกฝนมาอย่างดีจำนวน 8 คนเข้าร่วมในการศึกษาครั้งนี้ การศึกษานี้เป็นการทดลองแบบไขว้ อำพรางฝ่ายเดียว และสุ่มลำดับ กลุ่มตัวอย่างจะได้รับการสุ่มลำดับการทดสอบ 3 เงื่อนไข ได้แก่ 1) ดื่มเครื่องดื่ม 150 มล. ที่มีส่วนผสมคาเฟอีนปริมาณ 6 มก. ต่อน้ำหนักตัว 1 กก. 60 นาที ก่อนการวิ่ง และดื่มอีกครั้งในปริมาณ 3 มก. ต่อน้ำหนักตัว 1 กก. ในนาทีที่ 45 ระหว่างการวิ่ง (รับคาเฟอีนก่อนและระหว่างการวิ่ง), 2) ดื่มเครื่องดื่ม 150 มล. ที่มีส่วนผสมคาเฟอีนปริมาณ 6 มก. ต่อน้ำหนักตัว 1 กก. 60 นาที ก่อนการวิ่ง และในนาทีที่ 45 ระหว่างการวิ่งได้รับยาหลอก (รับคาเฟอีนก่อนวิ่งเพียงครั้งเดียว) และ 3) ดื่มเครื่องดื่ม 150 มล. ที่เป็นยาหลอกทั้งก่อนและระหว่างการวิ่ง (ยาหลอก) กลุ่มตัวอย่างทดสอบการวิ่งจนถึงระยะเวลาเหนื่อยหมดแรงบนลู่กลไฟฟ้าเพื่อทดสอบประสิทธิภาพของสมรรถภาพความอดทน การตอบสนองของสารชีวเคมีในร่างกาย และอาการของระบบทางเดินอาหาร โดยระดับคาเฟอีนในเลือด ระดับกรดไขมันอิสระในเลือด ระดับน้ำตาลในเลือด ระดับกรดแลคติกในเลือด อาการของระบบทางเดินอาหาร และระดับการรับรู้ความรู้สึกเหนื่อย วิเคราะห์ผลด้วยด้วยวิธีทดสอบความแปรปรวนแบบเกี่ยวข้องกันแบบสองทาง ระยะเวลาของการออกกำลังกายจนเหนื่อยหมดแรง และปริมาณการสูญเสียน้ำ วิเคราะห์ผลด้วยด้วยวิธีทดสอบแบบเกี่ยวข้องกันแบบทางเดียว กำหนดนัยสำคัญทางสถิติที่ระดับ .05 ผลการวิจัย การรับคาเฟอีนก่อนวิ่งเพียงครั้งเดียว (6 มก. ต่อน้ำหนักตัว 1 กก.) มีผลทำให้ระยะเวลาของการวิ่งจนเหนื่อยหมดแรงยาวนานกว่าอย่างมีนัยสำคัญทางสถิติเมื่อเปรียบเทียบกับยาหลอก (2.29%) การรับคาเฟอีนก่อนและระหว่างการวิ่งมีผลต่อระดับกรดไขมันอิสระในเลือด โดยพบความแตกต่างกันอย่างมีนัยสำคัญทางสถิติ เมื่อเปรียบเทียบกับกลุ่มยาหลอก ระดับของกรดแลคติกในเลือด และอาการของระบบทางเดินอาหารของกลุ่มที่ได้รับคาเฟอีนก่อนและระหว่างการวิ่ง มีความแตกต่างกันอย่างมีนัยสำคัญทางสถิติ เมื่อเปรียบเทียบกับกลุ่มที่ได้รับคาเฟอีนก่อนการวิ่งเพียงครั้งเดียวและกลุ่มยาหลอก และการรับรู้ความรู้สึกเหนื่อย ระดับน้ำตาลในเลือด และปริมาณการสูญเสียน้ำ ทุกกลุ่มไม่แตกต่างกัน สรุปผลวิจัย การได้รับคาเฟอีน 6 มก. …

Interrelationships Of Sociodemographic And Biological Factors In Breast Cancer Mortality Disparity Affecting Young Black Women, Richard Mutyabule

Walden Dissertations and Doctoral Studies

Despite improved overall survival among breast cancer patients, race and biological subtype-specific disparities persist. Subsequently, this retrospective longitudinal study, guided by ecosocial theory, examined associations between biological subtypes of breast cancer and patient-level sociodemographic factors on survival outcomes in women 25 to 44 years of age. Using Surveillance, Epidemiology, and End Results (SEER) database, 34,007 breast cancer cases between 2013 and 2018 were extracted. Kaplan Meier method and Cox proportional hazards model were used to examine time to event and the adjusted mortality risk by race and breast cancer subtype. There was a statistically significant difference in survival among young …

Exploring Quality Management Strategies To Mitigate Culture Shock Among Cochlear Implant Users, Victor Mulume' Ambila

Walden Dissertations and Doctoral Studies

AbstractAfter the cochlear implant (CI) activation period and therapy, adult CI users who travel overseas encounter culture shock factors that paralyze their coping capability, which need normalization through management strategies during the post-cochlear-implantation process (PCIP). In the structure of the conceptual framework, a plan is presented for addressing the management strategy. An integrated system of product-process-service-care portrays the product as an active implant within an individual bearer fostering a CI user’s physical, physiological, and psychological traits. The problematic aspects alter the end users’ coping capability in an unfamiliar host environment abroad. The qualitative research approach used was a single case …

Developing A Presimulation Protocol For Prostate Cancer Patients Undergoing Radiotherapy, Jennifer Wieworka

Walden Dissertations and Doctoral Studies

Inadequate preparation of prostate cancer patients undergoing radiation therapy (RT) can damage healthy tissue and cause long-term complications. Proper setup can reduce side effects. Currently, there are no standardized guidelines to help prepare patients for prostate radiation. Guidelines will help nurses coordinate care and manage symptoms for these patients. The purpose of this doctoral project was to address the gap in practice of the lack of a standardized process for implementing presimulation interventions for patients with prostate cancer undergoing RT by developing an evidence-based clinical practice guideline (CPG). The practice question for this project focused on the best practices contributing …

Hospital-Acquired Condition Ranking Score Among Types Of Safety-Net Hospitals, Jude C. Iruka

Walden Dissertations and Doctoral Studies

Abstract The Center for Medicare and Medicaid Services has been shifting from paying hospitals for the volume of services they delivered to paying them for the quality of those services, known as pay-for-performance, to incentivize hospitals to offer improved care at a lower cost. When a patient goes to the hospital to receive care for one condition and develops another condition during that hospital stay, the second condition is referred to as a hospital-acquired condition. It is anticipated that 1.7 million infections are acquired at some point in-hospital stay in the United States annually, resulting in nearly 100,000 deaths in …

Osteoporosis Risk Assessment Impacts Bone Densitometry, And Fall Fractures In Primary Care, Ifeoma Ude-Okoro

Walden Dissertations and Doctoral Studies

Abstract

In the United States, approximately 10 million adults 50 years and older are plagued by osteoporosis; this number has been projected to climb to 14 million by 2020. Osteoporosis is a debilitating disorder characterized by significant loss of bone mass and mineral density. Without proper screening and diagnosis, patients may not receive the appropriate medical treatments to avoid worsening of their condition and its associated complications. Nurses can help identify patients at risk for osteoporosis by administering osteoporosis screening during routine office visits. The practice-focused question asked whether the Fracture Risk Assessment Tool (FRAX) increased the proportion of bone …

Interrupted Time Series Analysis To Evaluate The Performance Of Drug Overdose Morbidity Indicators Shows Discontinuities Across The Icd-9-Cm To Icd-10-Cm Transition, Hannah Yang, Emilia Pasalic, Peter Rock, James W. Davis, Sarah Nechuta, Ying Zhang

Peer Reviewed Articles

Introduction: On 1 October 2015, the USA transitioned from the International Classification of Diseases, 9th Revision, Clinical Modification (ICD-9-CM) to the International Classification of Diseases, 10th Revision (ICD-10-CM). Considering the major changes to drug overdose coding, we examined how using different approaches to define all-drug overdose and opioid overdose morbidity indicators in ICD-9-CM impacts longitudinal analyses that span the transition, using emergency department (ED) and hospitalisation data from six states’ hospital discharge data systems.

Methods: We calculated monthly all-drug and opioid overdose ED visit rates and hospitalisation rates (per 100 000 population) by state, starting in January 2010. We applied …

The Lived Experiences Of Avoiding Recidivism Among African American Male (First-Time) Former Offenders, Jeff Hines

Walden Dissertations and Doctoral Studies

AbstractThe United States has a high recidivism rate within its criminal population, especially among men of African American descent. However, within this population, some first-time former offenders have used successful approaches to avoid re-incarceration. The objective of this study was to investigate how these first-time former offenders desist from crime and avoid recidivism. This was a phenomenological study, utilizing the Desistance Theory as a framework, to explore how these men survived the consequences of post-incarceration and remained crime-free. In-depth, semi-structured, open-ended interviews were conducted with six African American male first-time former offenders (age 25 and older) who were not on …

Importance Of Childhood Maltreatment On Borderline Personality In Adults: Meta-Analysis, Lisa Nicole Trentacosti

Walden Dissertations and Doctoral Studies

Early childhood maltreatment (CM) is a risk factor for later psychopathology specifically Borderline Personality Disorder (BPD). CM has been found to negatively affect social, emotional, and psychological development as well as the ability to foster and sustain interpersonal relationships throughout all stages of life. There are evidence-based interventions for different kinds of CM including Trauma-Focused Cognitive-Behavior Therapy (TF-CBT), Alternatives for Families - Cognitive Behavioral Therapy (AF-CBT), relaxation training, and social skills training. The current study is a meta-analysis of published research into CM as it contributes to BPD in adults and is designed to examine the effect size of childhood …

Responses Of Myxobacteria To Plant-Related Chemosignals Suggests Their Roles In The Rhizobiome, Barbara Iyare Adaikpoh

Electronic Theses and Dissertations

In the rhizosphere, plants curate and maintain distinct rhizobiome, some of which serve as secondary defense mechanisms against pathogenic microorganisms. Additionally, in response to biotic stress, plants generate phytohormones which regulate signaling pathways to activate systemic resistance. These phytohormones contribute to the chemical space within the rhizosphere in addition to other low-molecular-weight metabolites used for cell-to-cell communication within species and across kingdoms. However, little is known about the influences of stress-related phytohormones on beneficial bacteria even though biocontrol strategies abundantly explore plant-beneficial microorganisms to manage pathogens in agricultural systems. Myxobacteria are competent predators of plant pathogens and have demonstrated responses …

Influence Of Rage Signaling On Cellular Communication In Diabetes-Mediated Vascular Calcification, Amber Michelle Kennon

Electronic Theses and Dissertations

Chronic hyperglycemia is one of the main characteristics of type 2 diabetes mellitus (T2DM). With the increased prevalence of T2DM, the risk of cardiovascular complications, including heart attack or stroke, is increased. Complications linked to the vasculature are increased vascular calcification (VC) or mineral deposition within the medial layer of conducting arteries. Under calcification conditions, vascular smooth muscle cells (VSMCs) undergo an osteogenic switch to an osteoblast-like cell and begin producing bone proteins. Chronic hyperglycemia can also result in increased extracellular matrix (ECM) synthesis, accumulation, and crosslinking. One of the cell types responsible for increased ECM synthesis are ‘activated’ fibroblasts …