Medicine and Health Sciences Commons^™

The Relationship Between The Stigmatization Of Mental Illness, Communication Apprehension And The Willingness To Communicate, Madeleine Louise Winkler

All Graduate Theses, Dissertations, and Other Capstone Projects

This project explores how mental health stigmatization influences communication apprehension and the willingness to communicate about mental illness. A total of 153 people completed an online survey regarding three variables. Perceived stigma and communication apprehension when communicating about their own mental health were found to be positively correlated. Perceived stigma and communication apprehension when communicating about someone else’s mental health was also found to be positively correlated. Communicating about one’s own mental illness lead to higher levels of communication apprehension compared to communicating about someone else’s mental illness. Communication apprehension when talking about one’s own mental health and willingness to …

Field Test Of A Passive Infrared Camera For Measuring Trail-Based Physical Activity, Christiaan G. Abildso, Vaike Haas, Shay M. Daily, Thomas K. Bias

Faculty & Staff Scholarship

Introduction: Trails are ubiquitous and far-reaching, but research on the impact trails have on physical activity is limited by the lack of resource-efficient, accurate, and practical systematic observation tools. Commonly used infrared trail sensors count trail use and may broadly differentiate activity (i.e., bicyclist vs. pedestrian), but cannot detect nuances needed for outcomes research such as frequency, intensity, time, and type of activity. Motion-activated passive infrared cameras (PICs), used in ecological research and visitor management in wildlife areas, have potential applicability as a systematic observation data collection tool.

Materials and Methods: We conducted a 7-month field test of a PIC …

Interactions Between Gold Nanoparticles And Immunoglobulin Isotypes, Rick Hassan

Electronic Theses and Dissertations, 2020-2023

Gold Nanoparticles have piqued interest for use in a wide range of diagnostic and therapeutic applications including biosensors, assays, vaccine development, drug delivery, and photothermal therapy. While extensive research has been conducted, the applications of gold nanoparticles have yet to see the same level of commercial success as well-established methods such as ELISA and lateral flow immunoassays. Studies analyzing the efficacy of gold nanoparticle technologies in vivo and in vitro provide seemingly conflicting results that reflect a further need for investigation into the biological response of gold nanoparticles. A large factor in the variation is the nature of the interaction …

Pegloticase, Inderbir S. Padda, Rajat Bhatt, Mayur S. Parmar

HPD Articles

No abstract provided.

Apremilast, Inderbir S. Padda, Rajat Bhatt, Mayur S. Parmar

HPD Articles

No abstract provided.

Lenvatinib, Inderbir S. Padda, Mayur S. Parmar

HPD Articles

No abstract provided.

Covid (Sars-Cov-2) Vaccine, Inderbir S. Padda, Mayur S. Parmar

HPD Articles

No abstract provided.

Aducanumab, Inderbir S. Padda, Mayur S. Parmar

HPD Articles

No abstract provided.

Obeticholic Acid, Kristina Krupa, Vera Hapshy, Hiep Nguyen, Mayur S. Parmar

HPD Articles

No abstract provided.

Black Couples Filtering Their Love Stories Through The Use Of Social Media, Jeff Rocker

Department of Family Therapy Dissertations and Applied Clinical Projects

Black couples' use of social media for expressing their emotions needs to be explored to help them develop their narratives without external pressure. Narrative therapy is used to understand the difficulties ofholding on to unique personal narratives and preferred futures in the context of a hostile dominant discourse. The Black community has a long history of oppression, which makes their stories significant. Thus, social media posts by successful Black couples can be helpful in developing a new theory explaining personal narratives of Black couples in an online environment. These narratives provide information regarding themost common problems faced by Black people …

Appreciative Inquiry Of A Non-Profit Organization Transitioning To Teletherapy, Claudia Herrera

Department of Family Therapy Dissertations and Applied Clinical Projects

Mental health professionals have been required to make a transition to delivering services using technology during the COVID-19 pandemic. The non-profit agency participating in this study had already listed on its strategic plan the delivery of teletherapy. In 2020, due to the pandemic, the agency decided to expedite the delivery of teletherapy services. This study explored the experiences of the agency’s team, to determine what worked well while making this transition, as well as future dreams regarding the delivery of teletherapy. Appreciative inquiry was used as the method of data collection. Findings indicated the agency’s clinicians found keeping a positive …

Thinking Ethically About Hiv Pre-Exposure Prophylaxis: Retention In Care And Sexually Transmitted Infection Testing In A Southeastern United States Local Health Department In The Time Of Covid-19, Ellie Purdy

College of Graduate Studies: Theses & Dissertations

Local Health Departments (LHDs) are critical providers of Human Immunodeficiency Virus (HIV) and sexually transmitted infection (STI) prevention efforts. HIV Pre-Exposure Prophylaxis (PrEP) is an evolving public health initiative and practitioners should consider PrEP interventions in context of ethical decision-making and a broad STI prevention strategy as global incidence of bacterial STIs remains high and those at-risk for HIV are generally at-risk for other STIs. An evaluation of the Thinking Ethically framework and LHD PrEP services was performed to fill a gap in the literature and support program decision-making. A retrospective review of PrEP user medical records from a LHD …

Epidemiology Of Concussive Injuries In Collegiate Recreational Athletics, Maddison R. Flowers

College of Graduate Studies: Theses & Dissertations

Background: The epidemiology of concussion in collegiate and high school athletes has been extensively researched. Concussive injury in collegiate recreation, a less supervised sample, is limited. This preliminary study retrospectively examined the incidence and prevalence rates of concussive injuries in intramural and club sports at one institution. Methods: Injury reports were analyzed during the 2016-2019 calendar years. Concussion prevalence, incidence, and odds ratios (reported with 95% CIs) were calculated for intramural and club sports. Results: During the study period, a total of 805 injuries were reported between intramural and club sports with 111 injuries being documented as concussions. Intramural sports …

Occupational Depression, Cognitive Performance, And Task Appreciation: A Study Based On Raven’S Advanced Progressive Matrices, Renzo Bianchi, Irvin Sam Schonfeld

Publications and Research

The Occupational Depression Inventory (ODI) was recently developed to assess depressive symptoms that individuals specifically attribute to their work. Research on the criterion validity of the instrument is still in its infancy. In this study, we examined whether the ODI predicted performance on, and appreciation of, a cognitively challenging test. In light of the link established between clinical depression and neuropsychological impairment, and considering that individuals with depressive symptoms are more likely to feel helpless under challenging circumstances, we hypothesized that occupational depression would be associated with poorer cognitive performance and a darkened appreciation of the task undertaken. We relied …

The Scale Development Of Nursing Repositioning Practice For Bedridden Patients, Saudi Arabia, Abdul Kareem Suhel Hamadeh Iblasi

Chulalongkorn University Theses and Dissertations (Chula ETD)

This study aimed to explore, develop and test the psychometric properties of repositioning practice measures among nurses in Saudi hospitals and explores its components' psychometric properties. The study adopted the DeVellis scale development framework. Initially, the study clarifies the concept by literature review and interviewing six experts. Then a pool of 103 items was generated as the first draft. Over two rounds of expert revisions, the experts accept 61 items with content validity index means ( I-CVIs) equal to 0.91 and scale content validity = 0.81. later, the reliability with alpha Cronbach was 0.98. Next, this survey was passed for …

Effect Of Remaining Dentin Thickness And Primer Application Technique On Microtensile Bond Strength, Paphawee Somrit

Chulalongkorn University Theses and Dissertations (Chula ETD)

To evaluate the effect of primer application techniques, type of adhesives and remaining dentin thicknesses on microtensile bond strength (µTBS) of 4 different adhesive systems, 112 Flat occlusal surfaces of sound third molar were randomly allocated into 16 groups based on 2 remaining dentin thicknesses (RDT), 2 application techniques and 3 adhesive systems, e.g., Three step etch-and-rinse (Optibond FL; OFL), Two step self-etch (Clearfil SE Bond; CSE), and Universal adhesive (Single Bond Universal; SB). SB was applied in either etch-and-rinse (ER) or self-etch (SE) mode. Simulated pulpal pressure was performed during bonding procedure and 6-month water storage (37 oC). After …

The Impact Of An Alkasite Restorative Material On The Ph Of A Streptococcus Mutans Biofilm And Dentin Remineralization: An In Vitro Study, Pawinee Wiriyasatiankun

Chulalongkorn University Theses and Dissertations (Chula ETD)

This study investigated the effect of an alkasite material on the pH of Streptococcus mutans biofilm and dentin hardness. S. mutans biofilms were formed on a resin composite (FZ) and an alkasite (CN) materials and their pH determined after 24 h. Hydroxide, fluoride and calcium ions released from the materials were determined at 6 h, 1, 3, 7, 14, and 28 d. Fourteen human molar teeth were cut horizontally across the middle third of the crown, bisected mesio-distally into two sections and each section divided into two, yielding four quadrants. Quadrant 1 was a sound dentin control, quadrants 2-4 were …

Development Of Mucoadhesive Polymeric Nanoparticles For Intranasal Delivery Of Favipiravir In Treating Sars-Cov-2 Infection, Khent Alcantara

Chulalongkorn University Theses and Dissertations (Chula ETD)

Nanoparticles (NPs) have been used as an effective carrier for transmucosal delivery of drugs through their prolonged residence time and deposition, or the enhanced permeation through the mucosa. In this study, we aimed to design a nanocarrier using the combined mucoadhesive (M) properties of chitosan (CS) and alginate (ALG) polymers for the intranasal delivery of favipiravir (FVR) in treating SARS-CoV-2 infection. The optimized FVR-loaded mucoadhesive CS-coated ALG-NPs (FVR-MCS-ALG-NPs) rendered suitable size (233.5 nm), zeta potential (-21.6 mV), loading capacity (26.0%), and encapsulation efficiency (84.6%) for transmucosal delivery. Superior mucoadhesiveness and higher permeation and deposition in the porcine nasal mucosa of …

The Effectiveness Of Tibetan Yoga To Reduce Climacteric Symptoms And Enhancing Quality Of Life In Perimenopausal Women: A Community-Based Randomized Controlled Trial, Natsupa Archong

Chulalongkorn University Theses and Dissertations (Chula ETD)

Introduction: The climacteric symptoms has been the problems of most perimenopause women so far. This research examined the effect of using Tibetan Yoga in reducing climacteric symptoms and enhance quality of life of the perimenopause women. Objectives: To study the effect of Tibetan Yoga in reducing climacteric symptoms and increasing the quality of life in perimenopausal women. Method: This research is an experimental research. The research participants were sixty-four Thai perimenopausal women who lived in Moo 9, Lahan community, Bangbuatong District of Nonthaburi. Thirty-two of them were randomly selected to join the experimental group, the rest were in the controlled …

Development Of Elisa For Detecting Antibody Against Bartonella Spp. Specific Protein In Cats And Its Application In Natural Infection, Krissda Boonaramrueng

Chulalongkorn University Theses and Dissertations (Chula ETD)

This study aims to evaluate the risk factor and an association between Bartonella spp. infection and immune status by using retroviral-infected cats as an immunocompromised model and to develop the recombinant B. henselae specific antigen protein (17kDa and GroEL)-based ELISA test for antibody detection against Bartonella spp. infection in cats. From 2017 to 2020, 161 client-owned clinical healthy cats at veterinary clinics and hospitals in the Bangkok metropolitan area were recruited and tested for Bartonella spp. infection statuses (PCR and IFA serology), blood profiles, feline retroviral statuses (FIV and FeLV), and T lymphocyte subsets (CD4+, CD8+, and CD4+ to CD8+ …

Telementoring For Breast Surgeons Practicing In Remote Areas, Fatima Mubarik, Hania Shahzad, Syeda Sakina Abidi, Sana Zeeshan, Lubna Mushtaque Vohra, Sadaf Khan, Abida Khalil Sattar

Medical College Documents

Telementorship allows an expert surgeon to mentor another surgeon through an advanced procedure from a remote location via 2-way audio-visual communication. The current article was planned to review the existing literature and evaluate the utility of telementorship regarding educating rural surgeons in Pakistan about multidisciplinary breast cancer care. Publications from 2016 to 2020 were searched on PubMed and GoogleScholar and 10 most recent publications were selected. Review of literature revealed that even though telementorship in this context might be comparable to onsite mentorship, multiple concerns need to be addressed before its implementation. These include lack of concrete evidence regarding its …

Surgical Education And Training During The Covid-19 Pandemic: Strategies And Solutions For Pakistan, Edward Anthony Joseph, Russell S. Martins, Javeria Tariq, Namrah Aziz, Hina Inam, Mahim Malik

Medical College Documents

The coronovirus disease-2019 pandemic has severely impacted surgical education and training in Pakistan and worldwide, causing problems, such as risk of infection, limited hands-on training, examination delays, and trainee redeployment to non-surgical specialties. The current review was planned to describe innovative strategies adopted by surgical training programmes worldwide in order to suggest comprehensive recommendations at the level of the College of Physicians and Surgeons Pakistan and individual institutions to counter the challenges presented by the pandemic in Pakistan. The innovative use of technology, including open-access online educational portals, virtual educational activities and simulation-based learning, can help reform education delivery during …

Effect Of Imagery And Heart Rate Variability Biofeedback Training On Selected Soccer Skills Performance, Sara Majlesi

Student Works (2020-2029)

The present study aimed to evaluate the influence of PETTLEP video imagery (Physical, Environment, Task, Timing, Learning, Emotion and Perspective), heart rate variability biofeedback (HRVB), and concurrent intervention of both on selected soccer skill performances. The objective of this study was to evaluate the effect of PETTLEP video imagery, HRVB and concurrent intervention on soccer players' reactive motor skill test (RMST), sprint time, reactive agility, passing time, and passing accuracy. Participants of this study were Malaysian high school soccer players (N=64), with mean age of 15.31±1.83, who were assigned randomly into four groups: three experimental groups and one control group. …

Defining The Potential Of Gene Therapy With Bone Morphogenetic Proteins As A Novel Therapeutic Approach In Parkinson’S Disease, Susan Rebecca Goulding

Theses

Parkinson’s disease is a neurodegenerative disorder, characterised by the progressive degeneration of midbrain dopaminergic neurons, and the intracellular aggregation of the α-synuclein protein in neurons throughout the nervous system. These changes result in the characteristic motor impairments in Parkinson’s disease. Current treatments are solely symptomatic and therefore there is an unmet clinical need to develop new disease-modifying therapies that can alter disease progression. For over 25 years, one proposed experimental therapy has focused on the delivery of proteins called neurotrophic factors to the brain to prevent dopaminergic neuron degeneration. However, to date, clinical trials using the most well-known neurotrophic factors …

Risk Factors For Suicide In Bangladesh: Case-Control Psychological Autopsy Study, S M Yasir Arafat, M A. Mohit, Mohammad S I. Mullick, Russell Kabir, Murad M. Khan

Department of Psychiatry

Background: Suicide is an important, understudied public health problem in Bangladesh, where risk factors for suicide have not been investigated by case-control psychological autopsy study.
Aims: To identify the major risk factors for suicide in Dhaka, Bangladesh.
Methods: We designed a matched case-control psychological autopsy study. We conducted a semi-structured interview with the next-of-kin of 100 individuals who died by suicide and 100 living controls, matched for age, gender and area of residence. The study was conducted from July 2019 to July 2020.
Results: The odds ratios for the risk factors were 15.33 (95% CI, 4.76-49.30) for the presence of …

Development And Validation Of A Psychometric Scale To Assess Attitude Towards Safe Abortions In Pakistan, Xaher Gul, Junaid-Ur-Rehman Siddiqui, Miraal Mavalvala, Waqas Hameed, Muhammad Ishaque

Community Health Sciences

Despite severe health and economic consequences that women face because of the negative attitude of healthcare providers towards safe abortion and post-abortion care (SA/PAC), no psychometric tool has yet been validated for assessing the attitude towards SA/PAC. Only a handful of studies have attempted to assess healthcare providers' attitude towards safe abortions in Pakistan. Therefore, this study aimed to develop and validate a psychometric scale to assess attitude towards safe abortions in Pakistan. The study collected data from 106 workers of an NGO that provides SA/PAC through an online and anonymous survey using the organisation's network. The study used factor …

The Influence Of Coronavirus Disease-2019 (Covid-19) On Parkinson’S Disease: An Updated Systematic Review, Vikash Jaiswal, Danah Alquraish, Zouina Sarfraz, Azza Sarfraz, Shavy Nagpal, Prakriti Singh Shrestha, Dattatreya Mukherjee, Prathima Guntipalli, Diana F. Sánchez Velazco, Arushee Bhatnagar

Department of Paediatrics and Child Health

Background: COVID-19 has affected global communities with multiple neurological complications in addition to other critical medical issues. COVID-19 binds to the host's angiotensin-converting enzyme 2 (ACE2) receptors, which are expressed in the neurons and glial cells, acting as an entry port to the central nervous system (CNS). ACE2 receptors are abundantly expressed on dopamine neurons, which may worsen the prognosis of motor symptoms in Parkinson's disease (PD). SARS-CoV-2 may lead to an indirect response via immune-mediated cytokine storms and propagate through the CNS leading to damage. In this systematic review, we aim to provide thorough analyses of associations between COVID-19 …

Establishing The Minimally Important Clinical Difference For The Oral Health Impact Profile In Malaysians Provided With Removable Partial Dentures, Siti Fauzza Ahmad

Student Works (2020-2029)

Future demand for a removable partial denture (RPD) remains as more adults retain their natural teeth into old age. Partial tooth loss often leads to masticatory function disturbances and negatively affects the quality of life (QoL). Prosthodontic rehabilitation with RPD improves QoL; however, the statistically significant change with many Oral Health-Related Quality of Life (OHRQOL) instruments, may not be clinically meaningful. The Malaysian version of Oral Health Impact Profile, OHIP(M)-45 questionnaires has been validated and adapted; however, its clinical interpretability has not been established. The smallest change in OHRQoL score perceived by a patient as beneficial, following an intervention, is …

Motivation For Participating In Continuous Professional Development Among Selected General Practitioners In Kuala Lumpur, Malaysia: An Exploratory Case Study, Low Kien Yong

Student Works (2020-2029)

Continues Professional Development (CPD) activities are life-long learning engagements for general practitioners. It can enhance their medical competencies across cognition, psychomotor and affection domains, hence upholding safety and quality of healthcare services. Literature reported that motivation drives learning among general practitioners. However, limited studies explored the motivation from an educational lens. This study explored motivation(s) from the Andragogy and Self-Determination Theory perspectives in promoting active learning among general practitioners. This study also explored their perceptions of the amended law enforcement in Malaysia that mandates CPD participation. Three private general practitioners in Kuala Lumpur consented to participate in this study. In-depth …

Dirofilaria Immitis Prevalence In Canis Latrans In Kentucky, Melanie Ann Brandon

Murray State Theses and Dissertations

Dirofilaria immitis (canine heartworm) was found in forty-two (42) of the two hundred seventy-five (275) Canis latrans (coyote) necropsied in the state of Kentucky from November 27, 2019 through March 3, 2021. Thirty-five (35) of the positive cases were from western Kentucky region with the other seven spread across the state. With this group of coyotes, one hundred fifty-eight (158) were male and the other one hundred six-teen (116) were female. The estimated age ranged from a pup to senior dogs. A little over forty percent of the dogs were obtained through coyote/predator tournaments; the remaining were acquired from pest …