Medicine and Health Sciences Commons^™

The Prevalence Of Musculoskeletal Injuries Within The Center For Wellness In The Arts At Marshall University, Colin John Wakeman

Theses, Dissertations and Capstones

Background: The demands on successful performing artists are two-fold. First, they have to perform at a high skill level for their specific art, such as theater, marching band, dance, and color guard. Second, they need to achieve the aesthetic demands of their discipline. Musculoskeletal (MSK) injuries can impact either or both of these elements and affect their overall performance. If MSK injuries are not addressed early in a performer’s career, they can develop into chronic problems that take performers out of rehearsals, practices, and performances.

Purpose: This epidemiological study aimed to investigate the prevalence of MSK injuries within …

Ankle Muscle Activation And Mechanics During The Ebbet's Foot Drills, Quentin Adam Archuleta

Theses, Dissertations and Capstones

Introduction: The ankle is a complex structure of three joints that allow multiplanar motion (Brockett & Chapman, 2016). Lateral ankle sprains (LAS) are the most common injury seen today in both the general and athletic populations and have a high recurrence rate. When left untreated or mistreated, it often leads to developing chronic ankle instability or osteoarthritis, which a lower quality of life. Dr. Russ Ebbets created a set of foot drills with the claim that they can strengthen the muscles of the lower leg, lessen lower leg aliments, and the chances of a severe ankle sprain (Ebbets, 2011a). …

Fatigue-Related Jump Landing Knee Injuries In Dancers, Megan Holton

Theses, Dissertations and Capstones

Non-contact knee injuries are prevalent in dancers and have great financial and social costs. These injuries may be prevented with training that modifies jump landing movement patterns and improves lower body strength and cardiorespiratory fitness. Identifying the movement-based risk factors that are most strongly related to injury mechanisms allows healthcare providers to create effective training interventions. The purpose of this study was to determine the relationship between multivariate risk factors and injurious knee forces as a dancer lands from a jump. Twenty female dance students with at least eight years of experience were recruited. These dancers were injury-free and actively …

Role Of Na/K-Atpase Non-Enzymatic Signaling In Renal Proximal Tubule Sodium Transport, Shreya Tapan Mukherji

Theses, Dissertations and Capstones

The renal proximal tubule (RPT) is the center stage for renal handling of Na+ , a potent determinant of systemic Na+ and volume homeostasis in health and disease. In the RPT, through its classic ion-pumping function, Na + /K+ -ATPase (NKA) generates the Na+ gradient that drives apical Na+ absorption, mostly through Na+ /H+ exchanger (NHE3). In contrast, pharmacological evidence suggests that the activation of the NKA non-enzymatic signaling function, through Src and other signaling partners, triggers a cellular redistribution of NKA and NHE3 that decreases transcellular Na+ flux in cultured RPT cells. However, the physiological relevance of the nonenzymatic …

Do Needle Exchange Programs Cause More Harm To Injection Drug Users And Compromise The Safety Of The Communities In Which They Are In Place?, Amber L. Payne

Theses, Dissertations and Capstones

Needle Exchange Programs (NEP) are put in place in regions in the US, where illegal injectable drug use is prevalent, in order to decrease the amount of blood borne diseases by at least 10%, such as Hepatitis C and Human Immunodeficiency Virus (HIV), being spread throughout the drug-using community. People and Healthcare Professionals in these communities have questioned if NEPs have caused more harm to the drug users and if they have compromised public safety due to incorrect disposal of syringes.

During a study in 2011, the spread of blood borne diseases in areas where NEPs were present, decreased among …

Association Of Electronic Prescription In Controlled Substances Used, Archana Suwal, Jemima Akinyi Okonjo

Theses, Dissertations and Capstones

Introduction: Controlled substances have been described as pharmaceuticals or illegal medicines that act primarily on the central nervous system and could cause physical and mental dependence, eventually leading to addiction. Prescription opioids were a significant contributor to the opioid epidemic, accounting for more than 70,000 opioid-related overdose deaths, including illicit and prescription opioids, between 2018 and 2019. The Electronic Prescriptions for Controlled Substances (EPCS) initiative recently aimed to reduce rates of prescription opioid addiction, abuse, diversion, and death. The system for controlled substances had become more widely used as providers and governments trying to combat the opioid problem. Because …

Na/K-Atpase Alphα1 Regulates Adipogenesis Via Its Conserved Caveolin Binding Motif, Minqi Huang

Theses, Dissertations and Capstones

The Na/K-ATPase (NKA) was identified in 1957 by Dr. Jens C. Skou. It belongs to the P-type ATPase family, which can actively transport ions across cell membranes by using the energy from adenosine triphosphate (ATP) hydrolysis. During the second half of the 20th century, the molecular mechanism of the NKA catalytic cycle was clarified, and the isoform diversity of NKA in different species and organs was identified. The active ion transport through NKA generates cell membrane ion gradients and the electric potential. Hence, the enzymatic function of NKA is critical for cell viability as well as multiple physiological processes including …

Potential Counter Regulatory Effects Of A Gut Microbiota Metabolite In Alleviating Down-Regulation Krüppel-Like Factor 4 In Intestinal Inflammation, Ylva Forslund

Theses, Dissertations and Capstones

Inflammatory bowel disease (IBD) is a medical condition characterized by chronic inflammation of the intestinal epithelium. Krüppel-like factor 4 (KLF4), a zinc finger transcription factor, is vital for maintaining intestinal epithelial homeostasis. KLF4 promotes differentiation of goblet cells that generate the protective mucus layer. Reduced goblet cell number and defective mucus layer are associated with IBD. Shortchain fatty acids (SCFA) are known to play an important role in the maintenance of a strong and healthy intestinal epithelial layer and also in goblet cell differentiation. However, whether the positive effects of SCFAs on goblet cells are mediated, at least partly, via …

From Crib To Bench: Understanding Neonatal Opioid Withdrawal Syndrome (Nows) Using A Novel Rodent Model, Sarah Stevens

Theses, Dissertations and Capstones

As the opioid epidemic continues to grow, opioid use among pregnant women is increasing significantly. This has led to a steady rise in the number of infants born with neonatal opioid withdrawal syndrome (NOWS). Although short-term withdrawal symptoms associated with NOWS are well characterized, there are many gaps in our understanding of the short and long-term effects of prenatal opioid exposure. In CHAPTER 1, we describe the clinical presentation, associated neurodevelopmental challenges, and current treatments of NOWS. Our current understanding of the neuropathology of NOWS is limited, and therefore further research is needed. However, current animal models are limited by …

The Epigenetic Effects Of Omega-3 Fatty Acids In Diffuse Large B-Cell Lymphoma, Tanner Jeffrey Bakhshi

Theses, Dissertations and Capstones

Diffuse large B-cell lymphoma (DLBCL) is the most common type of lymphoma. It is an aggressive cancer, with 50-70% of patients diagnosed at an advanced stage and 30-50% of patients not cured by chemoimmunotherapy. DLBCL is almost always caused by genetic damage sustained during the germinal center (GC) reaction. The mechanisms that govern the GC reaction bear a striking resemblance to those that drive DLBCL. Genomic studies have shown that some of its most common mutations occur in genes that encode epigenetic modifiers, including the lysine (histone) acetyltransferases CREBBP and p300. These mutations prevent the acetylation of multiple histone residues, …

[W]Hole Health, Maudlin, Kimberly Williams-Roberts

Education Projects

Since the onset of COVID-19 during the early part of 2020, business owners and leaders have mostly focused on keeping their doors open amidst lockdowns and social distancing mandates. After over a year into the pandemic, the world is slowly opening up, despite the imminent threat of the virus. As we continue to adjust to this “new norm,” business leaders now must look at how these changes have and will affect their employees. The continuation of this process includes finding ways to provide the much-needed support to employees by way of improving wellness programs. Despite the availability of vaccinations, businesses …

Bridging Communication Disparities Between Medical Vendors And Healthcare Value Analysis Projects, Rose Rickrode

Education Projects

Vendor Value Analysis Consulting (Vendor-VAC) is represented by an online website created programmatically by Scarlett’s Web, Inc., at https://vendor-vac. This site has been developed to assist healthcare vendors who are seeking to properly market and present their products and/or services in a healthcare environment. Although vendors obtain personal visitation certifications in order to frequent a medical facility, their products and/or services must also be reviewed and technically certified via a defined criteria to be eligible for purchase. These standards are varied but specific to each organization and include assessment routes that fluctuate according to location and management. These diverse evaluation …

Wound Nurse Specialists’ Pressure Injury Knowledge And Specialty Support Surface Preferences, Catherine Koutroumpis

Master of Science in Nursing Theses and Projects

Low-level foam specialty support surfaces are negatively affecting the number of hospital-acquired pressure injuries that occur each year and overall skin health of acute care patients. Lack of knowledge by wound care specialists on different types of therapy could lead to patients not receiving the best possible specialty surfaces available. An online anonymous survey of 19 certified wound care nurses was conducted. The survey examined the nurses’ knowledge of pressure injuries using the Pieper Zulkowski Pressure Ulcer Knowledge test (PZPUKT) and choice of specialty support surface for prevention of pressure injuries. One hundred percent of nurses scored 80% and higher …

Utilization Of Hiv Care Coordination Programs To Address Gaps In Care, Jessica Chavis

Master of Science in Nursing Theses and Projects

This project evaluated the use of HIV care coordination programs in healthcare and their impact on care. The purpose of this project was to evaluate the role of HIV care coordination programs and their relationship with patient outcomes. The goal was to provide education on the benefits of these programs and how the lack of their presence in today’s healthcare system impacts transmission and general patient care. The plan of implementing a care coordination program at a local health department was established. Gaps in care, increasing medication adherence, and improving viral suppression rates were targeted by addressing social, mental, and …

Undergraduate Nursing Students’ Attitudes Toward Mental Illness And Psychiatric Nursing As A Career Choice, Sharon Zurline

Master of Science in Nursing Theses and Projects

Purpose: The purpose of this study is to examine the relationship between the attitudes of undergraduate nursing students toward mental illness, and the interest in choosing psychiatric nursing as a desirable career choice. Methodology: A nonexperimental descriptive study design was chosen for this study. Sample size of 18 undergraduate nursing students participated in the self-reported survey, The Mental Health Nursing Education Survey (MHNES) Part 2. This survey has 43-items that report the attitudes and beliefs toward people diagnosed with mental illness and towards mental health nursing and scored on a 7-point Likert Scale. Findings: Data reported from the survey report …

A Quality Improvement Project To Increase Intimate Partner Violence Screening On College Campuses, Becky Murck

Graduate Research Showcase

Abstract

A Quality Improvement Project to Increase Intimate Partner Violence Screening on College Campuses

Background: Sexual assault or rape on college campuses can be a life-changing event and goes unreported 80% of the time. Women are not screened for intimate partner violence (IPV) regularly when being seen in university student health settings, even though females ages 18 to 24 have the highest rape and sexual assault rates compared to females in all other age groups. Students that are victims of IPV may not report because of fear, embarrassment, or being unsure who to or where to report. Student health settings …

2020 Kentucky Nursing Workforce Report, Sydney P. Thompson

Center of Excellence in Rural Health Infographics

No abstract provided.

Practical Pearl: Sports After Covid 19 - January 2021, Yvonne Paris Md

Pediatrics Practical Pearls: Referral Guidelines for Common Problems

No abstract provided.

A Pilot One Group Feasibility, Acceptability, And Initial Efficacy Trial Of Listen For Loneliness In Lonely Stroke Survivors., Laurie A. Theeke, Jennifer A Mallow, Elliott Theeke

Nursing Faculty Publications

Loneliness is a prevalent problem for adult stroke survivors, and a known contributor to hypertension, secondary stroke, functional decline, poorer quality of life, and mortality in older adults. LISTEN (Loneliness Intervention using Story Theory to Enhance Nursing-sensitive outcomes), a theoretically based behavioral health intervention designed to target loneliness, in a sample of lonely survivors of ischemic stroke.

Prolonged Environmental Enrichment Promotes Developmental Myelination., Evan Z Goldstein, Vera Pertsovskaya, Thomas A Forbes, Jeffrey L Dupree, Vittorio Gallo

Pediatrics Faculty Publications

Postnatal neurodevelopment is profoundly influenced by environmental experiences. Environmental enrichment is a commonly used experimental paradigm that has uncovered numerous examples of experience-dependent plasticity in health and disease. However, the role of environmental enrichment in normal development, especially glial development, is largely unexplored. Oligodendrocytes, the myelin-forming glia in the central nervous system, provide metabolic support to axons and establish efficient saltatory conduction by producing myelin. Indeed, alterations in myelin are strongly correlated with sensory, cognitive, and motor function. The timing of developmental myelination is uniquely positioned to be influenced by environmental stimuli, as peak myelination occurs postnatally and continues into …

Sex-Specific Social Behavior And Amygdala Proteomic Deficits In, Maria Jesus Herrero, Li Wang, David Hernandez-Pineda, Payal Banerjee, Heidi Y. Matos, Meredith Goodrich, Aswini Panigrahi, Nathan Anthony Smith, Joshua G. Corbin

Pediatrics Faculty Publications

In humans, mutations in the transcription factor encoding gene, FOXP2, are associated with language and Autism Spectrum Disorders (ASD), the latter characterized by deficits in social interactions. However, little is known regarding the function of Foxp2 in male or female social behavior. Our previous studies in mice revealed high expression of Foxp2 within the medial subnucleus of the amygdala (MeA), a limbic brain region highly implicated in innate social behaviors such as mating, aggression, and parental care. Here, using a comprehensive panel of behavioral tests in male and female Foxp2 +/- heterozygous mice, we investigated the role Foxp2 plays …

Advancing And Promoting Community Health: Opportunities For Accountable Communities For Health And Community Health Centers, Helen Mittmann, Jeffrey Levi, Janet Heinrich, Feygele Jacobs, Rebecca Morris, Peter Shin

Geiger Gibson/RCHN Community Health Foundation Research Collaborative

Executive Summary:

Accountable Communities for Health (ACHs) are multi -sector, community-based partnerships that aim to address community health and social needs, and Community Health Centers (CHCs) provide important community-based healthcare services for underserved and medically vulnerable populations. Given the critical role that both ACHs and CHCs play in addressing health-related social needs and social determinants of health, a survey of ACHs on CHC engagement was conducted to better understand opportunities and challenges for CHC participation in ACHs. This survey, along with follow-up conversations with ACH and CHC representatives, confirmed that ACHs and CHCs are natural partners in the effort to …

Fusion, 2021, George Washington University, William H. Beaumont Medical Research Honor Society

Fusion

No abstract provided.

Scite: Contextualizing The Citation Count, Stacy Brody

Himmelfarb Library Faculty Publications

No abstract provided.

Cuentos - 2021, George Washington University, Medical Faculty Associates

Cuentos

Cuentos is the humanities magazine of the George Washington University Medical Faculty Associates Department of Internal Medicine.

Improving The Utilization Of Cnas In Pressure Ulcer Prevention, Jaclyn N. Bitterman

Doctor of Nursing Practice Projects

An estimated 2.5 million Americans are affected by pressure ulcers annually with the largest majority impacted the geriatric population. In order to achieve prevention of facility acquired pressure ulcers, the nursing team must properly identify patients at risk to prevent the injury associated with pressure. CNAs play a key role in this effort. The purpose of this project was used to develop, implement, and evaluate a training program for CNA students to improve knowledge and promote engaged attitudes in the prevention of pressure ulcers. Results of the project showed improvement after the training, but overall was not statistically significant. Overall …

Discharge Planning Considerations For Congestive Heart Failure: A Dnp Project, Jainarine Ramlochan

Doctor of Nursing Practice Projects

Abstract

Clinicians are challenged to prevent readmission of patients with congestive heart failure (CHF). The purpose of this project was to: 1) prepare students to better understand the discharge process for patients with CHF; and 2) obtain the opinion of nurses that were involved in the discharge process in the presence of COVID-19 Pandemic. The Delta Care Program (DCP) was used to guide the project and may be a useful tool for discharge planning. An intervention on use of the DCP was delivered to students (N = 83). Findings indicated that student nurses felt confident in the application of …

Atrial Fibrillation, Nicholas Anderson

Nursing Student Class Projects (Formerly MSN)

Atrial fibrillation (AF) is the most diagnosed cardiac arrhythmia that clinicians and patients should be educated on. Due to the increased morbidity, mortality, and healthcare costs associated with AF, it is important to have a solid understanding of the signs, symptoms, diagnosis, underlying pathophysiology, significance of the pathophysiology, treatments, and nursing implications that are involved with this cardiac arrhythmia. One of the most significant complications due to AF is stroke, thus stroke prevention measures such as oral anticoagulation should be considered.

Double-Blind, Randomized, Placebo-Controlled Phase Iii Clinical Trial To Evaluate The Efficacy And Safety Of Treating Healthcare Professionals With The Adsorbed Covid-19 (Inactivated) Vaccine Manufactured By Sinovac: A Structured Summary Of A Study Protocol For A Randomised Controlled Trial, Valerie Lau

VCU's Medical Journal Club: The Work of Future Health Professionals

The article presentation summarized the design of the Double-Blind, Randomized, Placebo-Controlled Phase III Clinical Trial to Evaluate the Efficacy and Safety of treating Healthcare Professionals with the Adsorbed COVID-19 (Inactivated) Vaccine Manufactured by Sinovac - PROFISCOV: A structured summary of a study protocol for a randomised controlled trial by Ricardo Palacios et. al. The Sinnovac vaccine is manufactured by Sinovac Life Sciences in Beijing, China. It uses the inactivated vaccine where the genetic material of the pathogen is eliminated by heat, radiation, or other chemicals. This was a Phase III trial, and it included a large sample size of 13,060 …

Lower Extremity Strengthening, Neuromuscular Re-Education And Graded Activity For A Runner With Distal Hamstring Tendinopathy: A Case Report, Tara Oyasato

Case Report Presentations

Research presentation slides:

Background and Purpose: Hamstring injuries are common injuries athletes face with high recurrence rates. Many hamstring injuries, including hamstring tendinopathy are caused by non-contact mechanisms like running due to its role in eccentrically controlling rapid knee extension and hip flexion. Despite its prevalence, there is controversy surrounding the optimal treatment of a hamstring strain. The purpose of this case study was to document the physical therapy (PT) interventions for a runner with an acute distal hamstring injury and tendinopathy. Case Description: The patient was a 23-year-old active male referred to outpatient PT with a diagnosis of patellar …