Medicine and Health Sciences Commons^™

Electroencephalography Resting-State Networks In People With Stroke, Dylan B. Snyder, Brian D. Schmit, Allison S. Hyngstrom, Scott A. Beardsley

Biomedical Engineering Faculty Research and Publications

Introduction

The purpose of this study was to characterize resting-state cortical networks in chronic stroke survivors using electroencephalography (EEG).

Methods

Electroencephalography data were collected from 14 chronic stroke and 11 neurologically intact participants while they were in a relaxed, resting state. EEG power was normalized to reduce bias and used as an indicator of network activity. Correlations of orthogonalized EEG activity were used as a measure of functional connectivity between cortical regions.

Results

We found reduced cortical activity and connectivity in the alpha (p < .05; p = .05) and beta (p < .05; p = .03) bands after stroke while connectivity …

It's About Time: Examining The Role Of Time Together And Perceived Stress In Couple Relationships, Rachel J. H. Smith

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Because stress is a common struggle in romantic relationships and because stress can spill over into couples’ interactions and affect their level of relationship connection, it is important to understand what can help couples adapt to stress and maintain meaningful relationships. Quality time together has been found to have positive effects on relationship outcomes overall. Additionally, family stress theory has posited that having sufficient resources can help couples adapt to stress and avoid a crisis situation. As such, time together was examined as a potential resource for couples to draw upon to adapt to the potential negative effects of perceived …

A Longitudinal Study Of Interprofessional Education In Graduate Students From Rehabilitation Sciences, Francesca Julia Hernandez

Open Access Theses & Dissertations

Background: The importance of interprofessional collaboration (IPC) and interprofessional education (IPE) have been well recognized in the healthcare field and health professions programs. However, the long-term benefits of IPE experiences for students from various health professions has not been well investigated.

Purpose: The purpose of this study was to examine the long-term effectiveness of IPE experiences on rehabilitation sciences graduate students’ interprofessional knowledge and perceptions of other disciplines’ roles and responsibilities across time.

Methods: A group of seventy-one students from occupational therapy (OT), physical therapy (PT), and speech-language pathology (SLP) graduate programs at the University of Texas at El Paso …

Determination Of Perceived Calorie Content Of Common Foods, Sarah Leticia Ruiz

Open Access Theses & Dissertations

Currently, dietary weight-loss interventions focus on recommended caloric intake aimed at creating an energy deficit through the use of calorie-based education. This approach assumes individuals can accurately estimate caloric content of foods and beverages, yet little is known about the validity of such assumptions. This study assessed the accuracy of perceptions of calorie content for individual food items and mixed meals and determined its association with education level, nutrition background, body composition, fruit and vegetable intake, and the domains of eating (emotional eating, uncontrolled eating, and cognitive restraint). A cross-sectional survey assessed calorie perceptions using both visual food displays and …

Suppression Of Inflammation Of Cytokine Following Induced Francisella Tularensis Infection, Nicole Renee Setzu

Open Access Theses & Dissertations

Francisella tularensis is intracellular bacteria which is the causative agent of the disease Tularemia. Highly virulent in both humans and animals, it takes only as few as 10 microorganisms to cause a lethal infection. The bacteria can enter via direct or indirect routes causing the activations of the host innate inflammatory response to ensue. The bacteria invade host dendritic cells and neutrophils but predominately macrophages. This causes a mass inflammatory response resulting in the cytokine storm. Activation of Natural Killer T (NKT) cells has been shown to suppress inflammation in in vivo studies. Development and optimization of an in vitro …

Effects Of Carbohydrate Mouth Rinsing Plus Ingestion On Cycling Time Trial Performance, Henry D. Gebhardt

Electronic Theses and Dissertations

Due to limited glycogen stores, carbohydrate (CHO) consumption during exercise is effective at improving performance in endurance events lasting longer than 90 minutes in duration. Recent research has established that CHO mouth rinsing may improve performance over shorter durations, independent of actual consumption. However, research is lacking in determining if an extended period of mouth rinsing has any additive benefit in conjunction with typical CHO beverage consumption over longer competition durations, where CHO ingestion/consumption is likely warranted. PURPOSE: Determine the effects of CHO mouth rinsing combined with consumption compared to CHO consumption alone on cycling performance. METHODS: Following …

The Effectiveness Of The Schroth Method In Treating Idiopathic Scoliosis In Pre-Adolescent, Adolescent And Adult Patients: A Retrospective Chart Review, Dave Bancuk, Jacob Nutter, Jessica Ramos

Masters Projects

INTRODUCTION: Adolescent Idiopathic Scoliosis (AIS) is a spine condition affecting 1-3% of the adolescent population in the United States. Of this group, approximately 0.5% require surgical intervention to correct the curvature.This results in approximately 29,000 surgeries performed in the United States each year on adolescents to treat AIS. This represents a considerable financial burden along with the risk of surgical complications, so exploring conservative alternatives to surgical treatment is a worthwhile area of research. The literature is lacking on the conservative treatment of scoliosis regarding the Schroth Method as a primary intervention. The purpose of this study was to determine …

Comparison Of Dynamic And Static Stretching Protocols On Hopping Performance In Female Collegiate Soccer Players, Emma Harkleroad

Honors Thesis

Comparison of Dynamic and Static Stretching Protocols on Hopping Performance in Female Collegiate Soccer Players

Emma Harkleroad

Director: Dr. Patti Berg-Poppe

The purpose of this study was to evaluate static, dynamic, and no stretching on triple hop distance among female collegiate soccer players. Twenty-one volunteers (ages 18-22) from a Division I women's soccer team were randomly grouped into one of 3 intervention rotation groups. All subjects participated in 5 minutes of dynamic, static, or no stretching protocols on each of 3 days, depending upon the rotation timeline. Active ankle dorsiflexion range of motion (AROM) measurements with knee extended and knee …

Characterization Of The Sneathia Amnii Cytotoxin And Its Potential Role In Health Disparities Affecting Women Of African Ancestry, Ivypel Amankwa-Asare

Undergraduate Theses and Capstone Projects

Women of African descent are more likely to develop bacterial vaginosis (BV) and bear twice the risk of preterm birth and the increased risk of other pregnancy complications. Sneathia amnii is a pathogenic anaerobe found in the female urogenital tract that is associated with adverse outcomes such as preterm birth, BV, and chorioamnionitis. S. amnii has been found at a greater prevalence in the vaginal microbiota of women of African ancestry, which links it to a potential role in the disparities observed in health outcomes for these women. S. amnii encodes the cytopathogenic toxin A (CptA), an exotoxin that perforates …

Development Of Malignancies And Their Outcomes In Patients Supported On Continuous-Flow Left Ventricular Assist Devices-A Systematic Review., Elizabeth J. Maynes, Jonathan S. Gordon, Matthew P. Weber, Thomas J. O'Malley, Tyler M. Bauer, Chelsey T. Wood, Rohinton J. Morris, Louis E. Samuels, John W. Entwistle, H. Todd Massey, Vakhtang Tchantchaleishvili

Department of Surgery Faculty Papers

Background: With increased use of continuous-flow left ventricular assist devices (CF-LVAD), development of malignant tumors in this population is not uncommon. We sought to evaluate malignancies in CF-LVAD patients and evaluate the outcomes of treatment strategies.

Methods: Overall, 18 articles consisting of 28 patients were identified who developed malignancies after CF-LVAD placement. Patient-level data were extracted for systematic review.

Results: Median patient age was 60 years [59-67] and 85.7% (24/28) were male. CF-LVAD was placed as bridge-to-transplant (BTT) in 60.9% (14/23) of patients. The three most common malignancy types were GI in 35.7% (10/28) of patients, lung in 21.4% (6/28) …

Forward-Thinking Design Solutions For Mechanical Circulatory Support: Multifunctional Hybrid Continuous-Flow Ventricular Assist Device Technology., Amy Throckmorton, Ellen Garven, Matthew Hirschhorn, Steven Day, Randy Stevens, Vakhtang Tchantchaleishvili

Department of Surgery Faculty Papers

No abstract provided.

Predictive Factors For Success Of Awake Proning In Hypoxemic Respiratory Failure Secondary To Covid-19: A Retrospective Cohort Study, Sujith V Cherian, Chang Li, Brad Roche, Stephan A Reyes, Siddharth Karanth, Aditya P Lal, Gabriel M Aisenberg, Rosa M Estrada-Y-Martin

Faculty, Staff and Student Publications

BACKGROUND: Awake prone positioning has been recommended as an adjunctive measure in spontaneously breathing patients with hypoxemic respiratory failure during the COVID-19 pandemic. It remains uncertain as to how long this should be implemented, what variables to follow and who would be the ideal candidates for this adjunctive therapy.

METHODS: A retrospective chart review of patients admitted from April to August 2020 within our institution with multifocal pneumonia and hypoxemic respiratory failure secondary to COVID-19 who underwent awake-proning for at least 3 hours was conducted.

RESULTS: Improvement in respiratory parameters including ROX (SpO2/Fio2/ Respiratory Rate) indices and inflammatory markers within …

Altruism And Self-Concept In Pediatric Intensive Care Unit Nurses: Is There A Relationship With Reports Of Workplace Violence?, Minnette Markus-Rodden

Seton Hall University Dissertations and Theses (ETDs)

Incidents of workplace violence (WPV) are pervasive in healthcare settings. WPV in the US occurs four times more frequently in the healthcare sector than in the private sector. However, the true incidence of WPV in healthcare settings is thought to be much higher secondary to significant under-reporting. The American Nurses Association (2019) reports, while one in four nurses are assaulted, only 20-60% of the incidents are reported. This extensive range is due to the lack of an accepted definition of what constitutes WPV, variable reporting mechanisms, and an overall perception by healthcare workers that WPV is “part of the job”. …

Implementation Of An Enhanced Recovery Protocol In Gynecologic Oncology., Tanvi V. Joshi, Shaina F. Bruce, Rod Grim, Tommy Buchanan, Sudeshna Chatterjee-Paer, Elizabeth R. Burton, Joel I. Sorosky, Mark S. Shahin, Mitchell I. Edelson

Abington Jefferson Health Papers

Enhanced Recovery after Surgery (ERAS) is an evidence-based approach that aims to reduce narcotic use and maintain anabolic balance to enable full functional recovery. Our primary aim was to determine the effect of ERAS on narcotic usage among patients who underwent exploratory laparotomy by gynecologic oncologists. We characterized its effect on length of stay, intraoperative blood transfusions, bowel function, 30-day readmissions, and postoperative complications. A retrospective cohort study was performed at Abington Hospital-Jefferson Health in gynecologic oncology. Women who underwent an exploratory laparotomy from 2011 to 2016 for both benign and malignant etiologies were included before and after implementation of …

Examination Of Orthodontic Expenditures And Trends In The United States From 1996 To 2016: Disparities Across Demographics And Insurance Payers, Man Hung, Sharon Su, Eric S. Hon, Edgar Tilly, Alex Macdonald, Evelyn Lauren, Glen Roberson, Martin S. Lipsky

Institute on Aging Publications

Background: Orthodontics prevent and treat facial, dental, and occlusal anomalies. Untreated orthodontic problems can lead to significant dental public health issues, making it important to understand expenditures for orthodontic treatment. This study examined orthodontic expenditures and trends in the United States over 2 decades. Methods: This study used data collected by the Medical Expenditure Panel Survey to examine orthodontic expenditures in the United States from 1996 to 2016. Descriptive statistics for orthodontic expenditures were computed and graphed across various groups. Trends in orthodontic expenditures were adjusted to the 2016 United States dollar to account for inflation and deflation over time. …

Sex As A Moderator In The Relationship Between Post-Operative Pain And Analgesics Administered In Children Undergoing Elective Surgery, Amber M. Osorno, Michelle A. Fortier, Zeev N. Kain, Brooke N. Jenkins

Student Scholar Symposium Abstracts and Posters

About 85% of children who undergo elective surgery experience pain post-operatively and many do not receive proper pain management care after discharge. Most parents lack an understanding of proper pain care management using analgesics upon discharge. Research reveals that adults rate girls as more sensitive to pain and that they display a greater amount of pain in a pediatric post-operative environment. In adulthood, women report more sensations of pain and have a higher pain tolerance, which can be attributed to physiological characteristics. Nonetheless, the social differences by which boys and girls experience pain and express their pain cannot be denied. …

The Relationship Between Perceived Neighborhood Disorder And Type 2 Diabetes Risk Across Different Racial/Ethnic Groups, Min Yu, Jennifer N. Robinette

Student Scholar Symposium Abstracts and Posters

Approximately 32 million Americans have Type 2 Diabetes and that number is growing rapidly. Type 2 Diabetes is sensitive to environmental factors, and higher prevalence rates are often observed in disordered neighborhoods (i.e., those with more trash and vandalism). Through discriminatory practices such as redlining, racially restrictive covenants, urban renewal, and gentrification, marginalized racial/ethnic groups are more likely to live in disordered neighborhoods compared to non-Hispanic Whites. These disparities may also contribute to similar disparities in Type 2 Diabetes rates. Yet, research indicates that there may be racial/ethnic differences in the interpretation of neighborhood disorder as a threat to health …

How Covid19 Has Impacted Students Nutrition And Eating Habits With The Abrupt Closure Of Restaurants And Campuses, Chloe Sermet

Student Scholar Symposium Abstracts and Posters

With the ongoing COVID-19 pandemic causing college campuses, restaurants, and businesses to shut down, many college students found themselves having to return home or find alternative food resources. Due to these factors, it was imperative to examine how college student’s eating habits have changed throughout the pandemic, dealing with lots of stressors, and whether having prior education on nutrition influenced those eating habits. To examine those effects, 17 nutrition minors and 126 non-nutrition minors participated in the current study in which they took the College Students Eating Habit survey and the Perception of Peer Pressure Scale. The outcome of the …

Vaccine Hesitancy, The Covid 19 Pandemic, And Christian Fundamentalism, Nicole Drew

Student Scholar Symposium Abstracts and Posters

Over the past few decades, religion has continued to move to the forefront of American politics, with many viewing fundamental Christianity as synonymous with the Republican Party. Donald Trump's presidency has increased this tenfold, with significant figures within American Christianity voicing their support for him and tying him into Biblical prophecies. In the media, this appears to have affected how this demographic views the COVID 19 pandemic. The literature in this area focuses heavily on American Christians' response to mask mandates, stay-at-home orders, and other attempts to mitigate the spread of the CoronaVirus; however, research on how this same demographic …

Computational Design Of Β-Fluorinated Morphine Derivatives For Ph-Specific Binding, Nayiri Alexander, Makena Augenstein, Angelina Sorensen, Matthew Gartner

Student Scholar Symposium Abstracts and Posters

Opioids such as morphine are important pain-relieving drugs but also carry a risk of harmful side effects including addiction. Morphine is active in both healthy and inflamed tissue, however, decreasing the pKa of the biochemically-active amine group can promote selective binding in the more acidic conditions of inflamed tissue and reduce harmful side effects associated with opioids. Herein, we explore the impact of fluorination on the pKa of fluoromorphine derivatives to identify which will bind selectively in inflamed tissue. Theoretical pKa values are determined at the M06-2X(SMD)/aug-cc-pVDZ level of theory to calculate the ΔGaq" …

Comparative Research Of Effective Treatment Measures For Postpartum Depression, Aunica Novacek

Physician Assistant Scholarly Project Papers

Postpartum depression is a mood disorder that includes depressive symptoms during the time period following childbirth. There are various possibilities for what may cause this disorder, but the drastic change in hormones after delivery can play a role. With the chance this disorder may be fatal to both the mother and child, an appropriate, effective, and safe treatment is necessary to control depressive symptoms. The standard, first-line pharmacotherapeutic option is a selective serotonin reuptake inhibitor (SSRI) antidepressant. SSRI antidepressants are well understood, but these medications may take time to become effective. Knowing this, medical professionals can find a more rapid …

Effect Of A Ketogenic Diet On Glycemic Control In Type 2 Diabetics, Steven William Moore

Physician Assistant Scholarly Project Papers

With the increasing rate of patients diagnosed with type 2 diabetes mellitus (T2DM) and the serious complications associated with this disease, there continues to be controversy surrounding the most effective way to manage glycemic control in this population. The intention of this meta-analysis is to determine the effect of a ketogenic diet as a first-line treatment option on glycemic control in type 2 diabetic patients. Effectiveness was determined by comparing the ketogenic diet to other popular diets recommended to diabetics by practitioners following guidelines set forth by the American Diabetes Association. Several high-quality studies were selected utilizing PubMed, Dynamed plus, …

Active Therapies In The Management Of Concussion And Post-Concussion Syndrome, Breanna Raquel Krueger

Physician Assistant Scholarly Project Papers

The purpose of this research and literature review is to evaluate the recently completed literature to provide guidance to medical providers of the safest and most efficacious treatment options for adolescent patients with concussion and post-concussion syndrome. The literature was searched for studies directly related to adolescents and active therapies such as physical therapy, vestibular rehabilitation, exertional therapy, and cognitive behavioral therapy. The search time frame implemented was studies completed within the last ten years. Ten studies met the final criteria. The research shows a substantial benefit for immediate cognitive and physical rest following a mTBI. The research suggests that …

The Role Of The Gut Microbiome In Autoimmune Disorders, Sierra Baxter

Physician Assistant Scholarly Project Papers

According to the National Institute of Health (NIH), it is estimated that over 24 million Americans are diagnosed with autoimmune disorders, and the cases are increasing (2005). A significant risk factor that has been linked to the formation of these diseases is the gut microbiome. The gut microbiome of the adult plays a vital role in the efficacy of the immune system. The purpose of this research and systematic literature review is to determine how the gut microbiome can influence autoimmune disorders. In this review, five databases were searched including PubMed, DynaMed, Cochrane Library, Embase, and Clinical Key. A variety …

Invasive Needling Therapy For Myofascial Pain Syndrome, Katelyn Corine Krueger

Physician Assistant Scholarly Project Papers

Myofascial pain syndrome (MPS) is one of the most common musculoskeletal conditions characterized by tight bands of fascia and muscle fibers known as myofascial trigger points (MTrP). Empirical evidence suggests that deactivation of MTrP’s is best accomplished with invasive needling therapy such as dry needling, trigger point injections, and Botulinum toxin-A (BTX-A) injections. The objective of this systemic review is to compare the effectiveness of various needling therapies on pain intensity and determine if ultrasound guidance and obtaining a local twitch response (LTR) improves clinical outcomes. A comprehensive search of five databases including PubMed, Science Direct, Google Scholar, Cochran, and …

Comparison Of Oral Glucose Tolerance And Hemoglobin A1c As An Initial Indicator Of Type 2 Diabetes, Shelby L. Knox

Physician Assistant Scholarly Project Papers

The purpose of this literature review was to evaluate the diagnostic utility of hemoglobin A1c (HbA1c) compared to oral glucose tolerance testing (OGTT) for diagnosis of type 2 diabetes. Databases ClinicalKey, PubMed, Dynamed, and CINAHL withdrew a total of 17 peer-reviewed cross-sectional and retrospective studies, secondary data and pooled data analyses, and meta-analyses. Inclusion criteria included human studies, black, white, Hispanic, and Asian populations, studies < 10 years old, individuals > 15 years of age, fasting plasma glucose in conjunction with OGTT, and subjects without known type 2 diabetes. Exclusion criteria included alternative forms of diabetes, screening and diagnosis of prediabetes, comparisons in relation to specific …

Cannabidiol: An Adjunctive Therapy To Risperidone For Autistic Children Experiencing Behavioral Outbursts, Cherie Dowell

Physician Assistant Scholarly Project Papers

The purpose of this systemic literature review was to evaluate the safety, efficacy, and tolerability of medical cannabis in the treatment of aggression, irritability, and self-injurious behaviors in autistic children that are currently receiving risperidone. For this literature review, DynaMed, Cochrane, PubMed, ClinicalKey, and CINAHL were searched using various keywords and phrases. Studies that were included in this review were published after 2005, were peer-reviewed, and included systemic reviews, journal articles, clinical trials, randomized control trials, and meta-analyses. Studies that did not directly discuss autism and behavioral issues; autism treatment with risperidone, medical cannabis, or cannabidiol; that did not specifically …

Comparison Of Conjunctive Probiotic Use Versus No Probiotic Use In Outcomes Of Antibiotic-Associated Diarrhea, Samantha L. Simley

Physician Assistant Scholarly Project Papers

Antibiotics are utilized in the medical community for the treatment of bacterial infections. Consequently, the use of antibiotics may result in certain gastrointestinal side effects. Antibiotic-associated diarrhea is one side effect that can be seen in patient populations that are on an antibiotic regimen. Due to this side effect profile, patient compliance on an antibiotic regimen may be compromised. This lack in patient compliance led to increased interest to determine if there are treatment options available to prevent or reduce instances of antibiotic-associated diarrhea. One treatment option of interest includes the use of probiotics. The purpose of this literature review …

The Efficacy Of Testosterone Replacement Vs Aromatase Inhibitors/ Serms In The Presence Of Hypogonadism, Tobias Charles Steen

Physician Assistant Scholarly Project Papers

The prevalence of male hypogonadism increases with age, although it can occur in any age group. Patients with hypogonadism can experience a wide range of symptoms including mood changes, decreased libido, decreased muscle mass, erectile dysfunction and bone loss. Traditionally, management of this condition has been accomplished through some form of testosterone replacement therapy (TRT). While TRT has proven effective at attenuating the symptoms of hypogonadism, it is not without side effects. TRT can at times be expensive, painful, cause gynecomastia, acne, water weight gain and infertility. Recently, medications such as selective estrogen receptor modulators (SERMs) and aromatase inhibitors (AIs) …

Anticholinergic Medications And Risk Of Developing Dementia, Heidi N. Artz Schmaltz

Physician Assistant Scholarly Project Papers

Abstract (to Come)