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2019

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Full-Text Articles in Medicine and Health Sciences

Pemberantasan Sarang Nyamuk 3m Plus Terhadap Kejadian Demam Berdarah Dengue Di Puskesmas Payung Sekaki Kota Pekanbaru; Studi Kasus Kontrol, Tyagita Widya Sari, Retno Putri Dec 2019

Pemberantasan Sarang Nyamuk 3m Plus Terhadap Kejadian Demam Berdarah Dengue Di Puskesmas Payung Sekaki Kota Pekanbaru; Studi Kasus Kontrol, Tyagita Widya Sari, Retno Putri

Jurnal Epidemiologi Kesehatan Indonesia

Demam Berdarah Dengue (DBD) adalah penyakit menular yang disebabkan oleh virus Dengue dan ditularkan melalui gigitan nyamuk Aedes aegypti. Dinas Kesehatan Provinsi Riau melaporkan jumlah kasus DBD sebanyak 277 dan Case Fatality Rate (CFR) DBD sebesar 1,4% pada tahun 2016, di mana kasus terbanyak berasal dari Kota Pekanbaru yaitu 58 kasus dengan CFR sebesar 0%. Adapun, CFR DBD di wilayah kerja Puskesmas Payung Sekaki meningkat dari 0% pada tahun 2015 menjadi 0,7% pada tahun 2016. DBD merupakan penyakit berbasis lingkungan yang dapat dicegah dengan melakukan tindakan pengendalian vektor, antara lain dengan pemberantasan sarang nyamuk (PSN) dan tindakan pencegahan lainnya. Akan …


Pengaruh Inisiasi Menyusu Dini Terhadap Kematian Neonatal Pada Bayi Berat Lahir >2500 Gram Dan Pada Bayi Berat Lahir Rendah Di Indonesia, Ana Maina Rezky, Asri C. Adisasmita Dec 2019

Pengaruh Inisiasi Menyusu Dini Terhadap Kematian Neonatal Pada Bayi Berat Lahir >2500 Gram Dan Pada Bayi Berat Lahir Rendah Di Indonesia, Ana Maina Rezky, Asri C. Adisasmita

Jurnal Epidemiologi Kesehatan Indonesia

Kematian balita banyak terjadi pada masa neonatal. Inisiasi menyusu dini merupakan salah satu bentuk perawatan esensial saat lahir dan sebagai kunci awal dalam meningkatkan kelangsungan hidup bayi neonatal. Penelitian ini bertujuan mengetahui pengaruh inisiasi menyusu dini terhadap kematian neonatal pada bayi berat lahir > 2500 gram dan pada bayi berat lahir rendah di Indonesia. Penelitian ini menggunakan data yang bersumber dari Survei Demografi dan Kesehatan Indonesia tahun 2012. Data yang dikumpulkan dalam SDKI diperoleh melalui wawancara responden menggunakan kuesioner. Metode pengambilan sampel yang digunakan dalam SDKI yakni pertama melakukan pemilihan sejumlah primary sample unit (PSU) secara probability proportional to size (PPS), …


Efek Asi Eksklusif Terhadap Stunting Pada Anak Usia 6-59 Bulan Di Kabupaten Bogor Tahun 2019, Hardya Gustada Hikmahrachim, Rinawati Rohsiswatmo, Sudarto Ronoatmodjo Dec 2019

Efek Asi Eksklusif Terhadap Stunting Pada Anak Usia 6-59 Bulan Di Kabupaten Bogor Tahun 2019, Hardya Gustada Hikmahrachim, Rinawati Rohsiswatmo, Sudarto Ronoatmodjo

Jurnal Epidemiologi Kesehatan Indonesia

Stunting, atau perawakan pendek, berhubungan erat dengan hambatan kemampuan kognitif dan kualitas hidup. Prevalensi stunting di Indonesia mencapai 30,8% tahun 2018. Stunting dipengaruhi pemenuhan nutrisi di awal kehidupan, salah satunya melalui ASI eksklusif. Meskipun cakupan ASI eksklusif di Indonesia sudah 74,5%, hubungan stunting dengan ASI eksklusif seringkali tidak konsisten akibat keberagaman kuantitas dan kualitas ASI. Penelitian ini ingin mengetahui efek ASI eksklusif terhadap stunting di Kabupaten Bogor, sebagai salah satu daerah tinggi stunting di Indonesia. Penelitian dengan desain potong lintang ini dilaksanakan di Puskesmas Kecamatan Ciampea, Kabupaten Bogor, pada Februari sampai April 2019. Kriteria inklusi adalah balita usia 6-59 bulan …


Kinerja Rumah Sakit Swasta Dengan Pembayaran Ina Cbgs Di Era Jaminan Kesehatan Nasional: Casemix, Casemix Index, Hospital Base Rate, Atik Nurwahyuni, Ery Setiawan Dec 2019

Kinerja Rumah Sakit Swasta Dengan Pembayaran Ina Cbgs Di Era Jaminan Kesehatan Nasional: Casemix, Casemix Index, Hospital Base Rate, Atik Nurwahyuni, Ery Setiawan

Jurnal Ekonomi Kesehatan Indonesia

Private hospitals must monitor their performance using indicators commonly used in DRG payment systems: casemix, casemix index and hospital base rate. This study aims to analyze the performance of private hospitals including casemix, casemix index and hospital base rate. This cross sectional study was conducted with a sample of 7 hospitals selected purposively representing private hospital type B, C, and D in 6 provinces. Casemix and CMI RS are strongly influenced by the hospital capacity, which the hospitals class B have higher casemix and CMI than class C and D hospitals. There is a phenomenon, CMI in class C hospitals …


Kajian Literatur Sistematis: Skema Pengendalian Biaya Dalam Asuransi Kesehatan Nasional Di Beberapa Negara, Eka Pujiyanti, Ery Setiawan, Euis Ratna Sari, Indah Pratiwi Suwandi Dec 2019

Kajian Literatur Sistematis: Skema Pengendalian Biaya Dalam Asuransi Kesehatan Nasional Di Beberapa Negara, Eka Pujiyanti, Ery Setiawan, Euis Ratna Sari, Indah Pratiwi Suwandi

Jurnal Ekonomi Kesehatan Indonesia

Cost-containment is one of several strategies to ensure the financial sustainability of the National Health Insurance scheme. Several cost-containment models were commonly globally, such as cost-sharing, capping, and others. This review aims to determine the costs and impacts of implemented policy schemes as cost-containment instruments in various countries. We performed a systematic review from several primary databases (Proquest, Pubmed, and Cochrane Library) with the primary intervention are the cost-sharing methods. The results of our review focused on the cost containment scheme from the government perspective, in which the context of social insurance can be a modification of payment systems, cost-sharing, …


Analisis Biaya Satuan (Unit Cost) Dengan Metode Activity Based Costing (Abc) Di Poliklinik Jantung Rsu Dr. H. Koesnadi Bondowoso, Sumiati Sumiati, Eri Witcahyo, Andrei Ramani Dec 2019

Analisis Biaya Satuan (Unit Cost) Dengan Metode Activity Based Costing (Abc) Di Poliklinik Jantung Rsu Dr. H. Koesnadi Bondowoso, Sumiati Sumiati, Eri Witcahyo, Andrei Ramani

Jurnal Ekonomi Kesehatan Indonesia

Determination of rate calculated based on unit cost, based on Bondowoso Regent Regulation Number 62 of 2017, RSU dr. H. Koesnadi Bondowoso unit cost calculates using the Double Distribution method. Double Distribution (DD) method is not appropriate to be applied because it does not reflect activity, method based on activity, precise and accurate so that it can provide the right information is Activity Based Costing (ABC) method. RSU Dr. H. Koesnadi Bondowoso has not made unit cost calculation using Activity Based Costing (ABC) method, especially for outpatient installation. The purpose of this research is unit cost analysis with Activity Based …


Kemampuan Dan Kemauan Pasien Umum Rawat Inap Dalam Membayar Pelayanan Kesehatan Rawat Inap Di Rumah Sakit Umum Kaliwates Kabupaten Jember, Yanuar Anafia, Eri Witcahyo Dec 2019

Kemampuan Dan Kemauan Pasien Umum Rawat Inap Dalam Membayar Pelayanan Kesehatan Rawat Inap Di Rumah Sakit Umum Kaliwates Kabupaten Jember, Yanuar Anafia, Eri Witcahyo

Jurnal Ekonomi Kesehatan Indonesia

testRational rates were determined by calculating unit costs into account characteristics of product as information related ability and willingness to pay. Ability and willingness were calculated for quality control and cost at the hospital. Community satisfaction index in Kaliwates General hospital released number of customer satisfaction that hasn’t met the standard was rate of inpatient services. Results of preliminary study on general inpatients were 70% having an estimated rate of less than rate set by the hospital, 20% said rates were less affordable and 10% couldn’t estimate rates, then this study was calculate ability and willingness to pay for inpatient …


Analysis Of Risk For Class Shifting And Determinants Of Bpjs Kesehatan Membership Using Generalized Ordered Logit-Unconstrained Partial Proportional Odds Model, Siskarossa Ika Oktora, Ika Yuni Wulansari, Geri Yesa Ermawan Dec 2019

Analysis Of Risk For Class Shifting And Determinants Of Bpjs Kesehatan Membership Using Generalized Ordered Logit-Unconstrained Partial Proportional Odds Model, Siskarossa Ika Oktora, Ika Yuni Wulansari, Geri Yesa Ermawan

Jurnal Ekonomi Kesehatan Indonesia

The main source of funding of BPJS Kesehatan comes from the different premium class in which the participant registered. The medical benefits among classes are equivalent, except inpatient facilities. But when the improvement health degree is not linear with the incurred costs, problem would arise. This study aims to analyze class shifting and determinants of BPJS Kesehatan membership. Around 1.53 percent of participants access higher classes, while 5.62 percent access lower classes. Class III participants with inpatient status severity level 2 and 3, reaching 41% and 43%, respectively. In addition, 60% of non-PBI participants are Class II premium participants; most …


Chemical Composition And Behavioural Responses Of Male And Female Bactrocera Dorsalis To Their Volatile Emissions, Fikira Kimbokota Dec 2019

Chemical Composition And Behavioural Responses Of Male And Female Bactrocera Dorsalis To Their Volatile Emissions, Fikira Kimbokota

Journal of Humanities and Social Sciences

Bactrocera dorsalis, (Tephritidae) presented a grave threat to a broad range of fruit and vegetables in the tropics, including Tanzania. Bactrocera dorsalis is among the most destructive tephritid fruit fly, causing devastating loss of fruits especially mango. Insects use olfactory cues to locate hosts, oviposition sites and mating, in which pheromones are believed to be a strong cue used by insect to locate their mates. However, due to their high ability to adapt and occupy different ecological niches into various agroecological zones, there is a need to evaluate pheromonal composition from time to time to improve their control strategies. Therefore, …


Help-Seeking From A Counsellor Or Psychotherapist: A Cross-Sectional Study Of Irish Adults, Damien Cassells Dec 2019

Help-Seeking From A Counsellor Or Psychotherapist: A Cross-Sectional Study Of Irish Adults, Damien Cassells

Articles

The factors that contribute towards an individual seeking help from a counsellor or psychotherapist for a mental, nervous or emotional problem are explored in this study. A multivariate logistic regression is applied to analyse data from the 2006 National Psychological Wellbeing and Distress Survey. Individuals living in rural areas and in towns with populations of between 5,000 and 10,000 people are found to be less likely to seek counselling, relative to individuals living in Dublin City. Respondents earning the lowest income were less likely to enter therapy compared with respondents earning the highest, while having private health insurance increased the …


Clinical Characteristics Of Children With Epilepsy Managed At An Urban Hospital In Africa: A Retrospective Study, Pauline Samia, Arwen Barr, Subira B. Levi, Kirsten A. Donald, Jo M. Wilmshurst, Charles R. Newton Dec 2019

Clinical Characteristics Of Children With Epilepsy Managed At An Urban Hospital In Africa: A Retrospective Study, Pauline Samia, Arwen Barr, Subira B. Levi, Kirsten A. Donald, Jo M. Wilmshurst, Charles R. Newton

Paediatrics and Child Health, East Africa

Background: Most children with epilepsy reside in resource-limited regions such as sub-Saharan Africa, where the majority of studies have been conducted in rural areas with limited investigations. Medical records from children with epilepsy seen at an urban hospital in Kenya were examined to provide a comprehensive description of epilepsy in children from this hospital.
Methods: A retrospective observational study was conducted which involved reviewing medical records of 426 epilepsy patients (260 males and 166 females) aged 0 - 18 years, seen in Nairobi, Kenya between February 2011 and December 2014. Results: The most frequent age at presentation; documented in 29% …


The College Academic Self-Efficacy Scale (Cases); An Indonesian Validation To Measure The Self-Efficacy Of Students, Ifdil Ifdil, Khairul Bariyyah, Ari Khusuma Dewi, Itsar Bolo Rangka Dec 2019

The College Academic Self-Efficacy Scale (Cases); An Indonesian Validation To Measure The Self-Efficacy Of Students, Ifdil Ifdil, Khairul Bariyyah, Ari Khusuma Dewi, Itsar Bolo Rangka

Jurnal Kajian Bimbingan dan Konseling

This study examines the inventory properties of the Indonesian version of The College Academic Self-Efficacy Scale (CASES) which is originally Western, and was developed by Owen, S. V., & Froman, R. D. in 1988 to determine the level of student self-efficacy. The multi-stage random sampling method was used with 342 students as participants in Indonesia. Furthermore, the validity was analyzed using Cronbach’s alpha item analysis that shows the coefficient of α > .3, and the data showed that 33 items of Indonesian CASES were valid. In addition, as regards reliability, Cronbach’s alpha was also used for the analysis, and the result …


Factors Affecting The Wisdom Of Counselors: Perceptions Of Indonesian Pre-Service Counselors, Herdi Herdi, Sunaryo Kartadinata, Agus Taufiq Dec 2019

Factors Affecting The Wisdom Of Counselors: Perceptions Of Indonesian Pre-Service Counselors, Herdi Herdi, Sunaryo Kartadinata, Agus Taufiq

Jurnal Kajian Bimbingan dan Konseling

Early theoretical and empirical studies have recommended scholars to explore the factors affecting wisdom of counselors. To enact this void, the present study explores the factors affecting wisdom from the perspectives of Indonesian pre-service counselors (henceforth, participants). This study employed survey design to capture the participants’ perceptions. Participants involved in this study were 517 sixth semester pre-service counselors from eleven Guidance and Counseling Departments in Indonesia. Data were collected using questionnaire of Counselor Wisdom Antecedents Scale in the form of Likert five-level scale. The data were then analyzed using descriptive statistics and exploratory factor analysis. The findings captured that there …


The Effect Of Social Support On Single Mothers’ Subjective Well-Being And Its Implication For Counseling, Alif Muarifah, Dian Ari Widyastuti, Indah Fajarwati Dec 2019

The Effect Of Social Support On Single Mothers’ Subjective Well-Being And Its Implication For Counseling, Alif Muarifah, Dian Ari Widyastuti, Indah Fajarwati

Jurnal Kajian Bimbingan dan Konseling

The present study aimed to discover the effect of social support on single mothers’ subjective well-being. This study employed a correlational approach. One hundred fifty nine single-mothers in Bantul regency, Special Region of Yogyakarta, Indonesia were involved in this study, determined using quota sampling. The data were collected using social support and subjective well-being scales. Simple linear regression was used to analyze the data. The present study exhibited that social support significantly affects single mothers’ subjective well-being. This study can be used as a reference proving that social support is much needed by a single-mother to obtain subjective well-being. Therefore, …


The Development Of Peace Counseling Model (Pcm): Strategy Of School Counselor To Reduce Students’ Aggressive Behavior, Wahyu Nanda Eka Saputra, Yulia Ayriza, Irvan Budhi Handaka, Ediyanto Ediyanto Dec 2019

The Development Of Peace Counseling Model (Pcm): Strategy Of School Counselor To Reduce Students’ Aggressive Behavior, Wahyu Nanda Eka Saputra, Yulia Ayriza, Irvan Budhi Handaka, Ediyanto Ediyanto

Jurnal Kajian Bimbingan dan Konseling

This study aimed to develop a counseling model to reduce students’ aggressive behavior, namely Peace Counseling Model (PCM). This counseling model uses the basic theory of peace education that is specifically implemented in counseling. This study adapted the research and development model formulated by Borg & Gall. The research used quantitative descriptive analysis. There was a strong agreement between experts and practitioners on the feasibility of the product being developed to be implemented by school counselor. The results of this study should be a reference to further research to test the effectiveness of PCM to reduce students’ aggressive behavior.


Clostridium Difficile In Asia: Opportunities For One Health Management, Deirdre A. Collins, Thomas V. Riley Dec 2019

Clostridium Difficile In Asia: Opportunities For One Health Management, Deirdre A. Collins, Thomas V. Riley

Research outputs 2014 to 2021

Clostridium difficile is a ubiquitous spore-forming bacterium which causes toxin-mediated diarrhoea and colitis in people whose gut microflora has been depleted by antimicrobial use, so it is a predominantly healthcare-associated disease. However, there are many One Health implications to C. difficile, given high colonisation rates in food production animals, contamination of outdoor environments by use of contaminated animal manure, increasing incidence of community-associated C. difficile infection (CDI), and demonstration of clonal groups of C. difficile shared between human clinical cases and food animals. In Asia, the epidemiology of CDI is not well understood given poor testing practices in many countries. …


Efficiency Of Students’ Needs Assessment Application Facilitated By Text Communication Media, Guruh Sukma Hanggara, Nora Yuniar Setyaputri, Restu Dwi Ariyanto Dec 2019

Efficiency Of Students’ Needs Assessment Application Facilitated By Text Communication Media, Guruh Sukma Hanggara, Nora Yuniar Setyaputri, Restu Dwi Ariyanto

Jurnal Kajian Bimbingan dan Konseling

Needs assessment is the main thing performed by school counselors as a basis for developing a guidance and counseling service program. In conducting needs assessment, problems that frequently occur are related to ratios, feasibility and practicality of instruments, as well as needs assessment procedures. One solution that can be used to overcome these problems is the use of application analysis needs of students based on text communication media. This research aims to determine the efficiency of students’ needs analysis application based on text communication media on vocational high school students. The research method used was experiment with the one-group pretest-posttest …


Cholangiocarcinoma Presenting As Humoral Hypercalcemia Of Malignancy: A Case Report And Literature Review, Burak Erdinc, Preethi Ramachandran, Ruchi Yadav, Sonu Sahni, Gardith Joseph Dec 2019

Cholangiocarcinoma Presenting As Humoral Hypercalcemia Of Malignancy: A Case Report And Literature Review, Burak Erdinc, Preethi Ramachandran, Ruchi Yadav, Sonu Sahni, Gardith Joseph

Touro College of Osteopathic Medicine (New York) Publications and Research

Humoral hypercalcemia of malignancy (HHM) is most commonly encountered in squamous cell carcinoma (SCC) of different organs, and It is characterized by elevated parathyroid hormone-related peptide (PTHrP) levels. It may be seen as a manifestation of cholangiocarcinoma (CCC) at presentation and later in the course of the disease. However, HHM due to intrahepatic cholangiocarcinoma is a rare association and is associated with a poor prognosis. We herein report a case of hypercalcemia presenting as the first manifestation of an underlying rare variant of intrahepatic cholangiocarcinoma. Our patient is a 57-year-old male who presented to the emergency room with severe symptoms …


New Statistical Method Identifies Cytokines That Distinguish Stool Microbiomes., Dake Yang, Jethro Johnson, Xin Zhou, Elena Deych, Berkley Shands, Blake Hanson, Erica Sodergren, George M. Weinstock, William D Shannon Dec 2019

New Statistical Method Identifies Cytokines That Distinguish Stool Microbiomes., Dake Yang, Jethro Johnson, Xin Zhou, Elena Deych, Berkley Shands, Blake Hanson, Erica Sodergren, George M. Weinstock, William D Shannon

Faculty Research 2019

Regressing an outcome or dependent variable onto a set of input or independent variables allows the analyst to measure associations between the two so that changes in the outcome can be described by and predicted by changes in the inputs. While there are many ways of doing this in classical statistics, where the dependent variable has certain properties (e.g., a scalar, survival time, count), little progress on regression where the dependent variable are microbiome taxa counts has been made that do not impose extremely strict conditions on the data. In this paper, we propose and apply a new regression model …


Effect Of Hospital Volume On Outcomes Of Total Hip Arthroplasty: A Systematic Review And Meta-Analysis, Syed Hamza Mufarrih, Muhammad Owais Abdul Ghani, Russell S. Martins, Nada Qaisar Qureshi, Sayyeda Aleena Mufarrih, Azeem Tariq Malik, Shahryar Noordin Dec 2019

Effect Of Hospital Volume On Outcomes Of Total Hip Arthroplasty: A Systematic Review And Meta-Analysis, Syed Hamza Mufarrih, Muhammad Owais Abdul Ghani, Russell S. Martins, Nada Qaisar Qureshi, Sayyeda Aleena Mufarrih, Azeem Tariq Malik, Shahryar Noordin

Department of Biological & Biomedical Sciences

Background: A shift in the healthcare system towards the centralization of common yet costly surgeries, such as total hip arthroplasty (THA), to high-volume centers of excellence, is an attempt to control the economic burden while simultaneously enhancing patient outcomes. The "volume-outcome" relationship suggests that hospitals performing more treatment of a given type exhibit better outcomes than hospitals performing fewer. This theory has surfaced as an important factor in determining patient outcomes following THA. We performed a systematic review with meta-analyses to review the available evidence on the impact of hospital volume on outcomes of THA.
Materials and methods: We conducted …


Collagen Fibrils And Proteoglycans Of Peripheral And Central Stroma Of The Keratoconus Cornea - Ultrastructure And 3d Transmission Electron Tomography, Aljoharah Alkanaan, Robert J. Barsotti, Omar Kirat, Adnan Khan, Turki Almubrad, Saeed Akhtar Dec 2019

Collagen Fibrils And Proteoglycans Of Peripheral And Central Stroma Of The Keratoconus Cornea - Ultrastructure And 3d Transmission Electron Tomography, Aljoharah Alkanaan, Robert J. Barsotti, Omar Kirat, Adnan Khan, Turki Almubrad, Saeed Akhtar

PCOM Scholarly Works

Keratoconus (KC) is a progressive corneal disorder in which vision gradually deteriorates as a result of continuous conical protrusion and the consequent altered corneal curvature. While the majority of the literature focus on assessing the center of this diseased cornea, there is growing evidence of peripheral involvement in the disease process. Thus, we investigated the organization of collagen fibrils (CFs) and proteoglycans (PGs) in the periphery and center of KC corneal stroma. Three-dimensional transmission electron tomography on four KC corneas showed the degeneration of microfibrils within the CFs and disturbance in the attachment of the PGs. Within the KC corneas, …


Sex Differences In Becoming A Current Electronic Cigarette User, Current Smoker And Current Dual User Of Both Products: A Longitudinal Study Among Mexican Adolescents, Rosibel Rodríguez-Bolaños, Edna Arillo-Santillán, Inti Barrientos-Gutiérrez, Luis Zavala-Arciniega, Charity A. Ntansah, Jim Thrasher Dec 2019

Sex Differences In Becoming A Current Electronic Cigarette User, Current Smoker And Current Dual User Of Both Products: A Longitudinal Study Among Mexican Adolescents, Rosibel Rodríguez-Bolaños, Edna Arillo-Santillán, Inti Barrientos-Gutiérrez, Luis Zavala-Arciniega, Charity A. Ntansah, Jim Thrasher

Faculty Publications

This study aimed to assess sex differences in predictors for becoming a current exclusive electronic cigarette (e-cigarette) user, current exclusive smoker, or current dual user (concurrent smoking and e-cigarette use). This longitudinal study included 2399 females and 2177 males who had tried neither cigarettes nor e-cigarettes at baseline and attended 57 middle schools in the three largest cities in Mexico. We estimated multinomial logistic models stratified by sex. At follow-up, the prevalence of current exclusive e-cigarette use was 6.4% for males and 5.5% for females; current exclusive smoking was similar among males (3.6%) and females (3.5%); dual use was 2.4% …


Glucocorticoids Rapidly Activate Camp Production Via GΑs To Initiate Non-Genomic Signaling That Contributes To One-Third Of Their Canonical Genomic Effects, Francisco J. Nuñez, Timothy B. Johnstone, Maia L. Corpuz, Austin G. Kazarian, Nicole N. Mohajer, Omar Tliba, Reynold A. Pannettieri Jr., Cynthia J. Koziol-White, Moom Roosan, Rennolds S. Ostrom Dec 2019

Glucocorticoids Rapidly Activate Camp Production Via GΑs To Initiate Non-Genomic Signaling That Contributes To One-Third Of Their Canonical Genomic Effects, Francisco J. Nuñez, Timothy B. Johnstone, Maia L. Corpuz, Austin G. Kazarian, Nicole N. Mohajer, Omar Tliba, Reynold A. Pannettieri Jr., Cynthia J. Koziol-White, Moom Roosan, Rennolds S. Ostrom

Pharmacy Faculty Articles and Research

Glucocorticoids are widely used for the suppression of inflammation, but evidence is growing that they can have rapid, non-genomic actions that have been unappreciated. Diverse cell signaling effects have been reported for glucocorticoids, leading us to hypothesize that glucocorticoids alone can swiftly increase the 3′,5′-cyclic adenosine monophosphate (cAMP) production. We found that prednisone, fluticasone, budesonide, and progesterone each increased cAMP levels within 3 minutes without phosphodiesterase inhibitors by measuring real-time cAMP dynamics using the cAMP difference detector in situ assay in a variety of immortalized cell lines and primary human airway smooth muscle (HASM) cells. A membrane- impermeable glucocorticoid showed …


Patient Safety Escape Room: A Graduate Medical Education Simulation For Event Reporting., Gretchen Diemer, Rebecca Jaffe, Dimitrios Papanagnou, Xiao Chi Zhang, Jillian Zavodnick Dec 2019

Patient Safety Escape Room: A Graduate Medical Education Simulation For Event Reporting., Gretchen Diemer, Rebecca Jaffe, Dimitrios Papanagnou, Xiao Chi Zhang, Jillian Zavodnick

Department of Emergency Medicine Faculty Papers

Introduction: Although residents are on the front lines of patient care, they enter few formal patient safety reports on the adverse events and near misses they witness. Demonstrating the rationale and mechanics of reporting may improve this.

Methods: We designed and implemented an escape room patient safety simulation to incorporate active learning, gamification, and adult learning theory into intern patient safety onboarding. Interns from all sponsoring institution programs participated, identifying, mitigating, and reporting a range of patient safety hazards. Props and faculty time were the major resources required.

Results: One hundred twenty interns participated in this simulation in June 2018. …


Risk Factors And Mortality Rates Associated With Invasive Group B Streptococcus Infections Among Patients In The Us Veterans Health Administration, Robin L.P. Jump, Brigid Wilson, Daniel Baechle, Sunah Song, Federico Perez Dec 2019

Risk Factors And Mortality Rates Associated With Invasive Group B Streptococcus Infections Among Patients In The Us Veterans Health Administration, Robin L.P. Jump, Brigid Wilson, Daniel Baechle, Sunah Song, Federico Perez

Faculty Scholarship

IMPORTANCE The incidence of invasive infections caused by group B Streptococcus (GBS) continues to increase in the United States. Although diabetes is a key risk factor for invasive GBS, the influence of long-term glycemic control is not well characterized; other risk factors and mortality rates associated with specific types of invasive GBS infections are unknown. OBJECTIVE To investigate risk factors and mortality rates associated with specific invasive GBS infectious syndromes. DESIGN, SETTING, AND PARTICIPANTS This cohort study used US Veterans Health Administration data to assess active users of the Veterans Affairs health care system between January 1, 2008, and December …


Point-Of-Care Versus Central Testing Of Hemoglobin During Large Volume Blood Transfusion., Justin Herman, Brian Park, Bharat K. Awsare, Frances Mae West, Denine Crittendon, Lilah Evans, Mary Harach, Julie Karp, Alexis R. Peedin, Marianna Lanoue, Barbara Goldsmith, Eugene P. Warnick, Michael Baram Dec 2019

Point-Of-Care Versus Central Testing Of Hemoglobin During Large Volume Blood Transfusion., Justin Herman, Brian Park, Bharat K. Awsare, Frances Mae West, Denine Crittendon, Lilah Evans, Mary Harach, Julie Karp, Alexis R. Peedin, Marianna Lanoue, Barbara Goldsmith, Eugene P. Warnick, Michael Baram

Division of Pulmonary, Allergy, and Critical Care Medicine Faculty Papers

BACKGROUND: Point-of-care (POC) hemoglobin testing has the potential to revolutionize massive transfusion strategies. No prior studies have compared POC and central laboratory testing of hemoglobin in patients undergoing massive transfusions.

METHODS: We retrospectively compared the results of our point-of-care hemoglobin test (EPOC®) to our core laboratory complete blood count (CBC) hemoglobin test (Sysmex XE-5000™) in patients undergoing massive transfusion protocols (MTP) for hemorrhage. One hundred seventy paired samples from 90 patients for whom MTP was activated were collected at a single, tertiary care hospital between 10/2011 and 10/2017. Patients had both an EPOC® and CBC hemoglobin performed within 30 min …


Comparison Of Three Different Techniques Of Inverted Internal Limiting Membrane Flap In Treatment Of Large Idiopathic Full-Thickness Macular Hole., Fariba Ghassemi, Hassan Khojasteh, Alireza Khodabande, Lauren A. Dalvin, Mehdi Mazloumi, Hamid Riazi-Esfahani, Masoud Mirghorbani Dec 2019

Comparison Of Three Different Techniques Of Inverted Internal Limiting Membrane Flap In Treatment Of Large Idiopathic Full-Thickness Macular Hole., Fariba Ghassemi, Hassan Khojasteh, Alireza Khodabande, Lauren A. Dalvin, Mehdi Mazloumi, Hamid Riazi-Esfahani, Masoud Mirghorbani

Wills Eye Hospital Papers

Purpose: To evaluate and compare three different techniques of inverted internal limiting membrane (ILM) flap in the treatment of large idiopathic full-thickness macular hole.

Methods: In a comparative interventional case series, 72 eyes from 72 patients with large (> 400 µm) full-thickness macular hole were randomly enrolled into three different groups: group A - hemicircular ILM peel with temporally hinged inverted flap; group B - circular ILM peel with temporally hinged inverted flap; and group C - circular ILM peel with superior inverted flap. Best-corrected visual acuity (BCVA), anatomical closure rate, and ellipsoid zone (EZ) or external limiting membrane (ELM) …


Molecular Serotype-Specific Identification Of Non-Type B Haemophilus Influenzae By Loop-Mediated Isothermal Amplification, Chika Takano, Yoko Kuramochi, Mitsuko Seki, Dong Wook Kim, Daisuke Omagari, Mari Sasano, Bin Chang, Makoto Ohnishi, Eun Jin Kim, Kazumasa Fuwa, Paul E. Kilgore, Tomonori Hoshino, Satoshi Hayakawa Dec 2019

Molecular Serotype-Specific Identification Of Non-Type B Haemophilus Influenzae By Loop-Mediated Isothermal Amplification, Chika Takano, Yoko Kuramochi, Mitsuko Seki, Dong Wook Kim, Daisuke Omagari, Mari Sasano, Bin Chang, Makoto Ohnishi, Eun Jin Kim, Kazumasa Fuwa, Paul E. Kilgore, Tomonori Hoshino, Satoshi Hayakawa

Department of Pharmacy Practice

In children, the incidence of pneumococcal meningitis has decreased since the introduction of pneumococcal conjugate vaccine (PCV7 and PCV13). However, since the introduction of the vaccine, developed countries have seen the emergence of non-PCV13 serotypes. However, invasive pneumococcal disease (IPD) caused by PCV13-targeted serotypes still represents an important public health problem in resource-limited countries. To develop a rapid, simple, and cost-effective assay to detect serotypes of Streptococcus pneumoniae, we developed a novel loop-mediated isothermal amplification (LAMP) assay based on the sequences available for the 13 capsular types that are included in PCV13: 1, 3, 4, 5, 6 A, 6B, …


Frontline Nurse Leader Orientation Programs: A Review Of Literature, Shanelle Renee House Dec 2019

Frontline Nurse Leader Orientation Programs: A Review Of Literature, Shanelle Renee House

DNP Qualifying Manuscripts

Abstract

Aim This manuscript aims to synthesize the literature on the skills and knowledge needed by frontline nurse leaders and effective orientation or training programs developed to meet those needs.

Background Frontline nurse leaders are often promoted to positions of leadership due to their strong clinical skills; they often do not receive formal training.

Evaluation A literature search was conducted to identify and critically appraise journal articles that discuss orientation and training programs offered to frontline nurse leaders.

Key Issues The literature review revealed that frontline nurse leaders require a variety of skills and knowledge to be successful. Orientation and …


Gender Based Violence And Health Effects, Tazeen Saeed Ali Dec 2019

Gender Based Violence And Health Effects, Tazeen Saeed Ali

School of Nursing & Midwifery

Gender Based Violence (GBV) violates the basic human right of a person’s physical, sexual and emotional integrity and health ([i]) such that globally, one out of every three women is subject to some form of violence, ranging from verbal and physical abuse to emotional blackmailing and psychological torture eventually leading to futile despair and hopelessness. The ironical perception of gender equality in our society is the root cause of gender based violence, with women being more afflicted by such a form of gender discrimination than men. [i]. Ali TS, Krantz G, Gul R, Asad N, Johansson E, …