Medicine and Health Sciences Commons^™

Delayed Umbilical Cord Clamping: Effects On Extrauterine Transition In Full-Term Infants, Brenna Ellington

Celebration of Research

The umbilical cord provides life-sustaining blood flow between the growing fetus and its mother throughout the length of the pregnancy. Upon delivery, the cord continues to pump nutrient-rich blood to the fetus until impeded by clamping or natural occlusion. A literature review of articles published from 2011 to 2018 was conducted in order to determine the effects of delaying cord clamping on extrauterine transition in full-term infants. It was found that a delay can in fact provide the infant with vital stores of hemoglobin, increasing iron status and improving not only hematologic function, but cardiovascular stability, neurologic development, and whole-body …

Literature Review Of Rural Water Fluoridation Cessation, Amanda Klyn, Vaughn Moser, Blake Miller, Samantha Benson

Celebration of Research

A literature review was performed between September 2018 and November 2018 to determine the effects of community water fluoridation cessation in rural communities, namely in Ida Grove, Iowa. Eleven articles were selected using inclusion and exclusion parameters, analyzed by the researchers, and summarized. Results of the literature review highlighted the benefits of fluoridation, which outweighed the possible risks. A plan of action was set out by the researchers to best promote optimal fluoridation in rural communities.

Best Practice For The Treatment Of Intertrigo, Melanie Enkhorn, Ingrid Ramirez, Moriah Lee, Hannah Barber

Celebration of Research

This literature review aims at exploring different treatment options for individuals diagnosed with intertrigo. Ten articles were reviewed between August and November 2018 with the purpose of helping Village Northwest Unlimited develop a therapeutic guideline for patients at risk or that are currently afflicted with the skin condition. After reviewing the literature, the researchers have concluded that there are multiple options for treatment rather than a single best treatment option for intertrigo. However, throughout this literature review, the researchers have provided many research articles that share possible treatment options for patients with intertrigo.

External Catheters And Reducing Adverse Effects In Female Inpatients, Ellie Bleeker, Allison Koehlmoos, Elizabeth Glover, Alexandria Helmink, Michelle Van Wyhe

Celebration of Research

A literature review was performed between the months of August 2018 to December 2018 on ways to decrease unnecessary usage of Foley catheters. Ten articles were reviewed focusing on bed-bound, incontinent women. Research was performed for Spencer Hospital looking at the various ways to decrease the usage, decrease catheter-associated urinary tract infections (CAUTI’s), and decrease skin breakdown from incontinence. Through the research, it was found that a large proportion of catheters are used when they are unnecessary. Indwelling catheters present a large risk for CAUTI’s, or if there is not one used, then the risk for skin breakdown from incontinence …

The Use Of Weighted Blankets In Patients With Anxiety, Kelsey Den Hartog, Mariah J. Jansen, Madison Godfredsen, Eden Burch

Celebration of Research

A literature review was conducted between the months of August 2018 and November 2018 to determine the effects of weighted blankets in patients with symptoms of anxiety. Ten articles were reviewed focusing on patients with anxiety-related symptoms. The purpose was to advocate for the purchase of more weighted blankets for the hospital in Spencer, Iowa. Medical staff currently do not have protocol in place regarding the use of the three weighted blankets the Spencer Hospital already owns. Conclusive evidence was found supporting the use of deep pressure touch stimulation through weighted blankets in patients with anxiety.

G.I. Jane Fem Etran Goes Corporate: An Exploration Of Post-9/11 Female Combat Veterans Transitioning To A Civilian Career, Tumona Austin

Dissertations

Purpose: The purpose of this multiple-case study was to explore the experiences of post- 9/11 female combat veterans transitioning from military service to civilian careers, using the Schlossberg transition model factors of situation, self, social support, and strategies.

Methodology: This multiple-case study identified and interviewed post-9/11 female combat veterans transitioning from active-duty to civilian career. Respondents were purposively chosen based on specific criteria and expert panel recommendations.

Findings: Examination of case-study interview data and artifacts from the 3 post-9/11 female combat veterans indicated nine major findings:

1. The factor of situation clearly outweighed the other Schlossberg factors in impact.

2. …

The Santa Clara, 2019-04-11, Santa Clara University

The Santa Clara

No abstract provided.

Publication Reform To Safeguard Wildlife From Researcher Harm, Kate A. Field, Paul C. Paquet, Kyle A. Artelle, Gilbert Proulx, Ryan K. Brook, Chris T. Darimont

Professional Science Research Ethics Collection

Despite abundant focus on responsible care of laboratory animals, we argue that inattention to the maltreatment of wildlife constitutes an ethical blind spot in contemporary animal research. We begin by reviewing significant shortcomings in legal and institutional oversight, arguing for the relatively rapid and transformational potential of editorial oversight at journals in preventing harm to vertebrates studied in the field and outside the direct supervision of institutions. Straightforward changes to animal care policies in journals, which our analysis of 206 journals suggests are either absent (34%), weak, incoherent, or neglected by researchers, could provide a practical, effective, and rapidly imposed …

Assessment Of Mglur5 Ko Mice Under Conditions Of Low Stress Using A Rodent Touchscreen Apparatus Reveals Impaired Behavioural Flexibility Driven By Perseverative Responses, Jisoo Lim, Eosu Kim, Hyun Jong Noh, Shinwon Kang, Benjamin U. Phillips, Dong Goo Kim, Timothy J. Bussey, Lisa Saksida, Christopher J. Heath, Chul Hoon Kim

Brain and Mind Institute Researchers' Publications

© 2019 The Author(s). Genetic and pharmacological manipulations targeting metabotropic glutamate receptor 5 (mGluR5) affect performance in behavioural paradigms that depend on cognitive flexibility. Many of these studies involved exposing mice to highly stressful conditions including electric foot shocks or water immersion and forced swimming. Because mGluR5 is also implicated in resilience and stress responses, however, apparent impairments in inhibitory learning may have been an artifact of manipulation-induced changes in affective state. To address this, we present here a characterization of cognitive flexibility in mGluR5 knockout (KO) mice conducted with a rodent touchscreen cognitive assessment apparatus in which the animals …

Trust The Process: A Templated, Centralized, And Protocolized Patient Safety Pilot Project To Improve Outside Admissions, Alan A. Kubey, Md, Jeffrey M. Riggio, Md

Department of Medicine Posters

Transfers are high-risk. Intra-hospital transfer processes research has improved protocols used nationally.1 Outside-hospital admissions remain without standards ensuring the transfer of the right information to the right clinician at the right time; presently, patients can arrive at a new hospital with limited-to-no information.2We trialed a novel process for outside (hospital, provider, or skilled nursing facility) admissions to a single academic medical center’s resident and- hospital-medicine-attending-based (“teaching”) medicine services.

The Role Of Anti-Müllerian Hormone As A Diagnostic Of Pcos, Kayla Lorsung

Nursing Capstones

No abstract provided.

Effects Of Elevated Thyroid Stimulating Hormone On Lactation In The Breastfeeding Woman, Kelsey Lindberg

Nursing Capstones

No abstract provided.

Health Insurance Coverage Of Recommended Gender-Affirming Health Care Services For Transgender Youth: Shopping Online For Coverage Information, Nadia L. Dowshen, Julie Christensen, Siobhan Gruschow

Student Papers, Posters & Projects

We assessed online health insurance plan indication of coverage and accessibility of information for recommended services for transgender youth (TY). Content analysis was performed for plans used at a pediatric Gender Clinic by reviewing information about coverage of puberty blockers, hormones, masculinizing chest surgery, and counseling. Transgender-specific exclusions and the time required for the research assistant to review each plan's online information were noted. No plan (0%; n=36) indicated coverage of all four categories of recommended services online. Forty-nine percent indicated ≥1 transgender-specific exclusion. The median time required for a research assistant to review online coverage information for each insurance …

Prognosis Of Patients With Aki After Percutaneous Mechanical Thrombectomy: A Retrospective Cohort Analysis, Hongchuan H. Coville Md, Tien-Min Lee Md, Hong Liang, Paul Alfino Md, Christopher Bray Md, Matthew Calestino Md

Internal Medicine

Percutaneous Mechanical Thrombectomy (PMT) is an endovascular procedure utilized in both arterial and venous thrombosis. Acute kidney injury (AKI) has been recognized as one undesired sequela of PMT. There is no study to investigate the outcomes in this specific patient population.

Management Of Parturient With Triplet Pregnancy And Placenta Percreta: Importance Of Multi-Disciplinary Approach, Samina Ismail, Akbar Azizullah

Department of Anaesthesia

Obstetric conditions like placenta percreta and multiple pregnancies can be extremely challenging as they pose a high risk for both the mother and infants. In placenta percreta, placental villi penetrate through the wall of uterus into the surrounding organs including the bladder and carry a risk of massive maternal bleeding. Multiple pregnancies have greater complication rate than that in singleton pregnancy. Successful management of such challenges are best done by a multidisciplinary teamwork, where all members of a perinatal team are involved in decision making and management. We report the successful management of a triplet gestation associated with placenta percreta.

Perfect Recipes For Obstetric Anesthesia: Need Of Caution In The Resource Constraint Environment, Samina Ismail, Malika Hameed

Department of Anaesthesia

No abstract provided.

Trials And Triumphs! Implementation Of A Phase I Clinical Trial Program In A Community-Based Hospital, Morgan M. Horton Bsn, Rn, Ccrc, Dana E. Clark Bsn, Rn, Ccrc, Ashley O. Patzuk Ocn

Patient Care Services / Nursing

No abstract provided.

Lack Of Association Between Dietary Inflammatory Index And Low Impact Fractures In The Brazilian Population: The Brazilian Osteoporosis Study (Brazos), Melissa Morimoto, Nitin Shivappa, Patricia De Souza Genaro, Ligia Araujo Martini, Natielen Jacques Schuch, James R. Hebert, Marcelo Medeiros Pinheiro

Faculty Publications

Introduction: Adequate nutrition, including intake of dietary calcium and vitamin D, is important to maintain bone health. Evidence suggests that a deficiency in micronutrients may contribute to bone loss during aging and exert generalized effects on chronic inflammation. Recently, the Dietary Inflammatory Index (DII) was developed to assess the inflammatory potential of individual diets. Our aim was to evaluate the DII in a representative sample and verify its association with low-impact fractures.

Methods: Individuals from The Brazilian Osteoporosis Study (BRAZOS) database had their DII calculated. BRAZOS is an important cross-sectional epidemiological study carried out with a representative sample of men …

Delay Discount Rate Moderates A Physical Activity Intervention Testing Immediate Rewards, Christine B. Phillips, Jane C. Hurley, Siddhartha S. Angadi, Michael Todd, Vincent Berardi, Melbourne Hovell, Marc A. Adams

Psychology Faculty Articles and Research

Financial incentives can increase physical activity (PA), but differences in the immediacy of reward delivery and individual differences in delay discount rates (i.e., higher discount values associated with less tolerance for delayed rewards) may explain differential responding. The current study tested whether delay discount rate moderated the relative effectiveness of immediate financial rewards on increasing daily PA. Inactive, overweight adults (ages 18–60, N = 96) were randomized to receive either smaller, immediate goal-contingent rewards or larger, delayed rewards for participation. Delay discount rates were derived for those who completed the Monetary Choice Questionnaire (N = 85). Linear mixed models tested …

Defining And Measuring Quality In Acute Paediatric Trauma Stabilisation: A Phenomenographic Study., Ralph James Mackinnon, Karin Pukk-Härenstam, Ulrica Von Thiele Schwarz, Christopher S. Kennedy, Terese Stenfors

Manuscripts, Articles, Book Chapters and Other Papers

Objectives: Trauma is the leading cause of death in children. The lack of an accepted definition of what constitutes a high-quality stabilisation of a traumatically injured child has limited the evaluation of direct interventions in simulation-based education and service-delivery models to improve trauma care. The aim of this study was to create a framework that delineates quality by exploring the perceptions of the multi-disciplinary team providing and improving this initial care.

Methods: Interviews were conducted with 36 experienced UK trauma team members and governance administrators (clinical directors to executive board level), from three standard UK trauma units. This study used …

Cryptococcal Meningitis In An Hiv-Negative Patient With Underlying Zinc Deficiency Following Partial Gastric Resection, Joseph Moran Do, Jaimin Patel Do, Shannon Kearney Do

Department of Medicine

No abstract provided.

An Evaluation Of Whether A Gestational Weight Gain Of 5 To 9 Kg For Obese Women Optimizes Maternal And Neonatal Health Risks, Abaigeal Thompson, James A. Thompson

School of Medicine Publications

Background

Maternal obesity has a wide range of health effects on both the pregnant woman and developing fetus. The clinical significance of these disorders, combined with a dramatically increasing prevalence of obesity among pregnant women has precipitated a major health crisis in the United States. The most commonly used recommendations for gestational weight gain were established by the Institute of Medicine (IOM) in 2009 and have become well known and often adopted. The authors of the IOM report acknowledged that the recommended gestational weight gain of 5 to 9 kg for obese women whose body mass index was greater than …

Coronary Angiography After Cardiac Arrest - The Right Timing Or The Right Patients?, Benjamin S. Abella, David F. Gaieski

Department of Emergency Medicine Faculty Papers

No abstract provided.

Gasdermin Pores Permeabilize Mitochondria To Augment Caspase-3 Activation During Apoptosis And Inflammasome Activation., Corey Rogers, Dan A. Erkes, Alexandria Nardone, Andrew E. Aplin, Teresa Fernandes-Alnemri, Emad S. Alnemri

Department of Biochemistry and Molecular Biology Faculty Papers

Gasdermin E (GSDME/DFNA5) cleavage by caspase-3 liberates the GSDME-N domain, which mediates pyroptosis by forming pores in the plasma membrane. Here we show that GSDME-N also permeabilizes the mitochondrial membrane, releasing cytochrome c and activating the apoptosome. Cytochrome c release and caspase-3 activation in response to intrinsic and extrinsic apoptotic stimuli are significantly reduced in GSDME-deficient cells comparing with wild type cells. GSDME deficiency also accelerates cell growth in culture and in a mouse model of melanoma. Phosphomimetic mutation of the highly conserved phosphorylatable Thr6 residue of GSDME, inhibits its pore-forming activity, thus uncovering a potential mechanism by which GSDME …

Comparison Of Head Impact Mechanisms And Type Of Play For Women’S Lacrosse Over 4 Years, Jessica Riquelme

Student Scholar Showcase

Context: Lacrosse is a fast growing contact sport, minimal studies have examined head impacts in women’s lacrosse.

Objective: To compare head impact mechanisms and type of play in women’s lacrosse.

Design: Descriptive epidemiology study.

Setting: Collegiate lacrosse fields.

Participants: 29 women’s lacrosse players (age=20.39±0.39 years, height=162.13+6.50 cm, mass=60.99+4.82 kg) participated over years. Intervention: Participants wore xPatch sensors during games and practices.

Main Outcomes Measures: Peak linear (PLA; g) and rotational (PRA; deg/sec²) accelerations of head impacts.

Results: Stick to head impacts occurred most often (IR=483.87, CI₉₅=397.30-570.45); whereas, head …

Comparing Men’S Soccer Head Impact Characteristics Over A Three Year Time Period, Karlie Ennis

Student Scholar Showcase

By studying head impacts over multiple seasons, injury patterns may be recognized which can lead to rule changes and other injury reduction measures. The purpose of our study was to compare head impact characteristics (impact location and mechanism) in men’s soccer over 3 years. We recruited 26 NCAA Division III intercollegiate male soccer players (age=19.64±1.25 years, height=181.70±5.80 cm, mass=76.98±10.19 kg) over 3years. X2 Biosystems xPatch sensors measured frequency and magnitude of all head impacts over a 10 g threshold. The overall male soccer player IR was 7.50/1000 athlete-exposures (CI₉₅=2.85-12.15). The most common head impact mechanism was ball …

An Anatomical And Functional Analysis Of Digital Arteries, Katie Highsmith

Student Scholar Showcase

Blood flow to the tissue of the hands and digits is efficiently regulated by vasoconstriction and vasodilation. Through a series of cadaveric dissection, we examined arteries in the hands and digits, including ulnar artery, radial artery, palmar arteries, and digital arteries, for their distribution (branching) patterns and morphological parameters (e.g., thickness, length between branches, external and internal diameters). Using data directly collected from three female cadavers as input variables to our mathematical model, we simulated vasoconstriction (-20% and -10% diameter) and vasodilation (+10% and +20 diameter) to evaluate the extent of changes in blood volume and flow within the arteries. …

Exploration Of Prostate Cancer Cells: The Significance Of Active Herv, Dakota Shepherd

Student Scholar Showcase

The second most common cancer in men is prostate cancer. Prostate cancer is traditionally diagnosed by a digital rectal exam. Blood tests can also be used to test for PSA (prostate-specific antigen). These two methods can be used together but can sometimes provide both false negative and false positive results. A new method of testing for prostate cancer could prove to be beneficial. Previous studies have shown that active HERV sequences have been identified in some cancers, including prostate cancer. We hypothesize that the presence of active HERV in prostate cancer lines is significant. In this study, rabbit polyclonal antibodies …

Mobilization Of Calcium Across Mineralized Tissues In Yellow Perch, Perca Flavescens, Taylor Bopp

Student Scholar Showcase

Bones in many higher teleost fish, such as percids and centrarchids, lack osteocytes that function as both chemo- and mechano-sensors, and thus, are not actively involved in homeostasis of blood calcium level. Nonetheless, the vertebrae of yellow perch, Perca flavescens (P. flavescens), living in darker and low calcium (Ca) water, have demonstrated adaptive modeling and remodeling of vertebrae to be more mineralized and thus enhance transmission of the axial muscle torque into the thrust force for the C-start predator escape behavior. The prey-predator interaction is expected to occur at closer range between prey fish and predator fish in …

The Effect Of Previous Medical History On Student-Athlete Quality Of Life, Rachael Watkins

Student Scholar Showcase

Health-Related Quality of Life (HRQL) assessments can provide Athletic Trainers with information about student-athletes’ overall well-being and health. The objective of this study was to examine the association between personal and family reports of medical history and HRQL in collegiate student-athletes. We recruited 271 student-athletes (age=19.00±1.15 years, height=175.18±4.29 cm, mass=72.29±12.03 kg). The independent variables included the presence of any family (parents, siblings, grandparents) or any personal history of balance disorders, psychological disorders, memory disorders or history of headaches. The dependent variables included the 9 subsets of HRQL (anxiety, depression, fatigue, pain interference, pain intensity, physical function, sleep disturbance, social roles) …