Medicine and Health Sciences Commons^™

Camel Anatomy; More Than Just A Hump, Michael Chase

The Review: A Journal of Undergraduate Student Research

The one-humped camel (Camelus dromedarius) is capable of living in extreme, arid environments due to its numerous anatomical adaptations. Its modified features of the muscular system, integument, skeletal system, and several internal organs allow this animal to survive in such harsh environmental conditions. Many of these adaptations allow for conservation of energy and water as well as improvement of locomotion to acquire scarce resources. In this paper we will look more closely at some of these adaptations and determine their function in promoting the survival and reproduction of the one-humped camel in desert environments.

Pain Management For Intrauterine Device Insertion And Endometrial Biopsy, Michelle Lipton-Carroll

Evidence-Based Practice Project Reports

Intrauterine device (IUD) insertions and endometrial biopsies (EMB) can be painful in office gynecological procedures. In the clinical setting used for this evidence-based project (EBP) it was noted there was no consistent pain management being used for these procedures. For this EBP project a protocol for pain management during IUD insertions and EMBs was developed and implemented into this clinical setting. The protocol was created from an exhaustive literature search, which yielded six pieces of high-level evidence of good quality. The evidence supported the use of a 1% lidocaine paracervical block prior to IUD insertion and a 2% lidocaine intrauterine …

Using The Ebus Scope In The Esophagus, Yousef Shweihat, Shantanu Singh

Internal Medicine

This chapter aims at introducing the interested Pulmonologist/Interventional Pulmonologist to the esophageal ultrasound. In this chapter, we give short descriptions of some technical aspects of the endobronchial ultrasound (EBUS) scope and explain in detail why we believe the EBUS scope is well suited to be an esophageal scope in the hands of the trained pulmonologist. The chapter then explains indications and benefits of this procedure that we consider central to the practice of chest physicians. We also describe in steps how to reach each lymph node station using the EBUS scope as a EUS scope (EUS-B) from our own experience. …

Eus-B For The Interventional Pulmonologist Using The Ebus Scope In The Esophagus, Yousef Shweihat, Shantanu Singh

Internal Medicine

This chapter aims at introducing the interested Pulmonologist/Interventional Pulmonologist to the esophageal ultrasound. In this chapter, we give short descriptions of some technical aspects of the endobronchial ultrasound (EBUS) scope and explain in detail why we believe the EBUS scope is well suited to be an esophageal scope in the hands of the trained pulmonologist. The chapter then explains indications and benefits of this procedure that we consider central to the practice of chest physicians. We also describe in steps how to reach each lymph node station using the EBUS scope as a EUS scope (EUS-B) from our own experience. …

Tumor-Derived Extracellular Vesicles Require Β1 Integrins To Promote Anchorage-Independent Growth., Rachel M. Derita, Aejaz Sayeed, Vaughn Garcia, Shiv Ram Krishn, Christopher D. Shields, Srawasti Sarker, Andrea Friedman, Peter Mccue, Sudheer Kumar Molugu, Ulrich Rodeck, Adam P. Dicker, Lucia R. Languino

Department of Cancer Biology Faculty Papers

The β1 integrins, known to promote cancer progression, are abundant in extracellular vesicles (EVs). We investigated whether prostate cancer (PrCa) EVs affect anchorage-independent growth and whether β1 integrins are required for this effect. Specifically using a cell-line-based genetic rescue and an in vivo PrCa model, we show that gradient-purified small EVs (sEVs) from either cancer cells or blood from tumor-bearing TRAMP (transgenic adenocarcinoma of the mouse prostate) mice promote anchorage-independent growth of PrCa cells. In contrast, sEVs from cultured PrCa cells harboring a short hairpin RNA to β1, from wild-type mice or from TRAMP mice carrying a β1 conditional ablation …

Ms211: Texas Natural Resource Conservation Commission (Tnrcc) [Readme Tnrcc], Armin Weinberg

Works on Radiation Effects: 1990-2020

Describes the files in this folder that summarize my disappointment in the TX agencies failure to include radiation/nuclear threats to the environmental assessment they were conducting. See more at Armin Weinberg, PhD Papers and its finding aid.

Editorial: Invertebrate Models Of Natural And Drug-Sensitive Reward, Moira J. Van Staaden, Robert Huber

Biological Sciences Faculty Publications

The relationship between insects and humans is a complex one, characterized biotically as commensalism, mutualism, or parasitism. This collection of papers reveals yet another dimension, in which shared history invests invertebrate models with the power to interrogate critical challenges to the human reward system. As humans we take pride in approaching a given scenario rationally, in considering the possible options, assigning them values, and then choosing that which maximizes one's individual outcomes. So, why do drug addicts make choices that inevitably lead to ruinous consequences? Fundamentally, addiction appears to impair the very ability to form considered judgments, as it strips …

The Effect Of Perceived Level Of Social Support On The Fear Of Falling, Kali A. Todd

Honors College Theses

Background: Perhaps the most prevalent cause of anxiety among the elderly is the fear of falling (FOF), considering that a fall can lead to serious complications and the decline of health. Kumar et al. found that subjects with a FOF usually have less social support. Therefore, increased social support could possibly decrease the FOF, thus decreasing the likelihood of a fall overall. The purpose of this study is to examine the relationship between the amount of perceived social support one receives and the FOF among people ages 60 and up. Methods: In order to measure FOF and social support among …

Moral Ecology In Nursing: A Pluralistic Approach, Darcy Copeland

Nursing Faculty Publications

Moral dilemmas are present in all settings in which nurses work. Nurses are moral agents who must make moral decisions and take moral action in very complex social systems. Nurses are accountable for their actions, and it is therefore imperative that they have a solid foundation in ethics. There are multiple ethical frameworks nurses can utilize to justify their actions. A theory of moral ecology is presented here as a way to conceptualize the relationships between these frameworks. The first two steps of moral action, moral sensitivity and moral judgment, are explored in a pluralistic context. Specifically, multiple ethical frameworks …

Mindful Meditation Practice For Imaging Professionals, Tanya M. Custer, Kim Michael

Posters and Presentations: Medical Imaging & Therapeutic Sciences

Although a career in medical imaging is very fulfilling and rewarding, research shows that health care professionals are becoming more prone to burnout. The healthcare environment can be face-paced, stressful and demanding. Burnout syndrome results from emotional exhaustion that causes depersonalization and decreased professional accomplishment.1-3 Burnout can have a negative impact not only on the individual, but the environment as well. Decreased patient satisfaction and increased errors are both associated with burnout in the healthcare setting.2

Mindfulness can be defined as the awareness that emerges through paying attention on purpose, in the present moment, and non-judgmentally to the unfolding of …

“Evaluating Knowledge And Perspectives Of Behavior Analytic Language Strategies In The Clinical Practice Of Speech-Language Pathology”, Mackenzie Sturman

Honors Theses

Research shows that principles of applied behavior analysis (ABA) may be beneficial to language acquisition. Speech-language pathologists (SLPs) have the responsibility of assessment, diagnosis, and treatment for individuals with various speech and language impairments, and work directly with language instruction. However, there is limited knowledge of the degree to which SLPs use concepts of behavior analytic language interventions in clinical practice for individuals of varying language and communication disorders. This study investigated the extent to which practicing SLPs use language strategies from ABA in their clinical practice. A qualitative approach was utilized by conducting individual semi-structured interviews with four practicing …

Looking For Age Differences In Self-Driving Vehicles: Examining The Effects Of Automation Reliability, Driving Risk, And Physical Impairment On Trust, Ericka Rovira, Anne Collins Mclaughlin, Richard Pak, Luke High

Publications

Purpose

Self-driving cars are an extremely high level of autonomous technology and represent a promising technology that may help older adults safely maintain independence. However, human behavior with automation is complex and not straightforward (Parasuraman and Riley, 1997; Parasuraman, 2000; Rovira et al., 2007; Parasuraman and Wickens, 2008; Parasuraman and Manzey, 2010; Parasuraman et al., 2012). In addition, because no fully self-driving vehicles are yet available to the public, most research has been limited to subjective survey-based assessments that depend on the respondents’ limited knowledge based on second-hand reports and do not reflect …

The Protective Influence Of Relationship Commitment On The Effects Of Facebook Addiction On Marital Disaffection, Irum Saeed Abbasi, Michelle Drouin, Jayson L. Dibble, Brandon T. Mcdaniel Phd

Health Services and Informatics Research

ABSTRACT Previous research has suggested that Facebook use can lead to adverse romantic relationship outcomes due to interpersonal conflicts, interactions with potential romantic alternatives, and jealousy. However, these associations have been explored mainly with undergraduates, focusing primarily on conflict rather than emotional disengagement. The current study examined the associations between Facebook addiction and marital disaffection (e.g., loss of love, emotional disengagement) amongst 138 (95 females and 43 males) cohabiting married Facebook users residing in the United States. The results revealed that Facebook addiction and marital disaffection were positively related, even after controlling for relationship commitment. Additionally, greater relationship commitment weakened …

Childhood Obesity: A Childhood Nightmare, Sarah S. Teemul

Undergraduate Research Symposium

There is an alarming increase in the rates of childhood obesity. The social issues that obese children face begin with the society’s behavior towards them. Obesity is viewed by the public as a lifestyle disease therefore, victim blaming is involved. Society created how a “perfect” body should be and this has led to bullying. People are taken advantage of due to low-economics status, resulting in the purchase of unhealthy food. The challenges that overweight children face from society are important to acknowledge because understanding the social issues can prevent this epidemic. Although, society has come to terms with the epidemic, …

Development Of A Protofibril-Selective Sandwich Elisa To Analyze Alzheimer’S Amyloid-Β Levels, Marina Villoch Diaz Maurino, Cristina Sinobas Pereira

Undergraduate Research Symposium

Protein aggregation is recognized as an important contributing factor to several neurodegenerative diseases such as Alzheimer’s disease (AD). One of the peptide involved is amyloid-β (Aβ), a 40-42-residue peptide and the primary component of the senile plaques found in AD brains. Aβ aggregations can be found in the form of protofibrils, monomers, and fibrils intermediates. However, only protofibrils have been shown to be a crucial factor in pathogenicity due to their toxicity. This research involves the development of a novel protofibril-selective sandwich ELISA to determine Aβ levels in AD so it can be used for further research as a biomarker, …

Regulation Of Mrna Decay By Puf Proteins Is Dependent On Environmental Conditions, Anthony Fischer, Alexandra Hamrick, Shayna Mueller

Undergraduate Research Symposium

The nucleus of a eukaryotic cell contains the genetic code within DNA that directs growth and function of the cell. The genes contained in DNA make copies of themselves called RNAs, which are molecules able to leave the nucleus and direct protein synthesis. Over- or under-production of any one protein can cause cell malfunction and disease. Regulation of RNA lifespan is one method to ensure proper protein production. The Puf family of RNA-binding proteins regulate mRNA lifespans by controlling the rate of mRNA decay. More specifically, Puf proteins stimulate the removal of the poly(A) tails of mRNAs, which results in …

Cloning, Sequencing, Expression And Characterization Of An Alzheimer’S-Specific Monoclonal Antibody, Anna K. Jones, Thao Pham

Undergraduate Research Symposium

Alzheimer’s disease (AD) is characterized by chronic inflammation and neurodegeneration, which leads to loss of cognitive functions. Dr. Nichols’ research laboratory is studying the neurological effects associated with AD. Amyloid precursor protein (APP) is a membrane spanning protein whose primary function is unknown, but it is associated with many tissue types and found clustered at the synapse of neurons. APP can be cleaved by secretases into 40 or 42 amino acid fragments called amyloid beta protein (Aβ). These cleaved amyloid-β proteins can accumulate (aggregate) and form extracellular plaques in AD brains. Antibodies are normally produced in an adaptive immune response …

The Santa Clara, 2019-04-25, Santa Clara University

The Santa Clara

No abstract provided.

Crossbow Bolt Injury To The Heart, Deanne Jacobs, Claire Hardman, Syed A. Zaman, Akpofure Peter Ekeh

Department of Surgery Faculty Publications

Case summary A 33-year-old woman was transferred from an outside hospital with a penetrating injury to her right chest. The patient was shot with a crossbow with the entry site to the right breast/chest and a transmediastinal trajectory. She was intubated prior to arrival due to difficulty breathing. Her vital signs remained stable and within normal limits, with good breath sounds, and no evidence of pneumothorax on chest X-ray. The tip of the bolt was palpable at the patient’s left midaxillary line. Chest X-ray in trauma bay showed the transmediastinal trajectory, and the bolt appeared to have a field point …

Triggered Electrical Stimulation Cueing To Address Hypofunctioning Peroneus Muscle In The Treatment Of Chronic Ankle Instability: Two Repeated Single Case Designs, Paul Ullucci, Cheryl J. Hickey, Deborah L. Walker, Kelly R. Hosey

Health & Wellness Department Faculty Publications and Research

Background: Approximately two million ankle sprains occur in the United States annually. Lateral ankle sprains (LAS) account for 85% of all ankle sprains, 74% of those individuals report continued symptoms following the initial insult. Persistent pain and instability following ankle sprain is indicative of chronic ankle instability (CAI). There are many interventions to address hypofunctioning muscle including electrical stimulation (ES) and it is known that peripheral ES changes muscle behavior. The purpose of this pilot study was to investigate the effect of electrical stimulation of the peroneal muscles combined with 3 exercises for the treatment of CAI.
Methods: Two participants …

Chemotherapy-Induced Oral Mucositis Is Associated With Detrimental Bacterial Dysbiosis., Bo-Young Hong, Takanori Sobue, Linda Choquette, Amanda K Dupuy, Angela Thompson, Joseph A Burleson, Andrew L Salner, Peter K Schauer, Pujan Joshi, Evan Fox, Dong-Guk Shin, George M. Weinstock, Linda D Strausbaugh, Anna Dongari-Bagtzoglou, Douglas E Peterson, Patricia I Diaz

Faculty Research 2019

BACKGROUND: Gastrointestinal mucosal injury (mucositis), commonly affecting the oral cavity, is a clinically significant yet incompletely understood complication of cancer chemotherapy. Although antineoplastic cytotoxicity constitutes the primary injury trigger, the interaction of oral microbial commensals with mucosal tissues could modify the response. It is not clear, however, whether chemotherapy and its associated treatments affect oral microbial communities disrupting the homeostatic balance between resident microorganisms and the adjacent mucosa and if such alterations are associated with mucositis. To gain knowledge on the pathophysiology of oral mucositis, 49 subjects receiving 5-fluorouracil (5-FU) or doxorubicin-based chemotherapy were evaluated longitudinally during one cycle, assessing …

Improving Antimicrobial Stewardship Programs In Small Community Hospitals Through An Assessment And Feedback Model, Philip Chung, Kate Tyner, Scott Bergman, Terry Micheels, Mark Rupp, Michelle Schwedhelm, Maureen Tierney, Muhammad Salman Ashraf, Trevor Van Schooneveld

Posters and Presentations: Nebraska ASAP

Small community hospitals often lack expertise and resources for antimicrobial stewardship program implementation. Using an assessment-and-feedback model, Nebraska ASAP performed onsite assessment of antimicrobial stewardship efforts in 5 small community hospitals and provided facility specific feedback on implementation/augmentation of antimicrobial stewardship program. As a result of this model, participating small community hospitals were able to increase the number of antimicrobial stewardship core elements implemented while reducing antibiotic use and incidence of CDI.

Routine Patellar Resurfacing During Total Knee Arthroplasty Is Not Cost-Effective In Patients Without Patellar Arthritis, Harold I. Salmons, Bs, Benjamin Zmistowski, Md, Yale A. Fillingham, Md, Derek Ward, Md, Robert P. Good, Md, Jess H. Lonner, Md

Department of Orthopaedic Surgery Posters

• During total knee arthroplasty (TKA), whether or not one should routinely resurface the patella is controversial.
• Leaving an unresurfaced patella following index TKA may lead to anterior knee pain (AKP), patellofemoral crepitus, and future secondary resurfacing operations.
• However, routinely resurfacing the patella (PR) may lead to patellar fracture, aseptic loosening, patellar instability, avascular necrosis, and patellar clunk.
• The purpose of the present study is to utilize the existing level one evidence to assess the cost-utility of routine patella resurfacing during primary TKA.
• Hypothesis: Selective resurfacing of the patella is more cost effective than routine patellar resurfacing during primary TKA.

A State Of Uncertainty: An Analysis Of Recent State Legislative Proposals To Regulate Preventive Services In The United States, Maxim Gakh, Cody Cris, Prescott Cheong, Courtney Coughenour

School of Public Health Faculty Research

This policy brief examines preventive services state legislation trends in the United States during uncertainty regarding the Affordable Care Act (ACA), which requires certain coverage of 4 evidence-based preventive services categories without additional patient costs under §2713. We used a legal mapping approach to search for and analyze state legislation related to preventive services proposed or enacted over a 25-month period of ACA uncertainty. We screened 1231 bills and coded the 76 screened-in bills. Next, we determined their characteristics and examined trends. Bills originated in 28 states, and 69.7% were not enacted. Only 3.9% contained requirements contingent on ACA modifications. …

Research, Evidence-Based Practice And Quality Improvement, Tonya Traylor

DNP Final Reports

Background: The United States is in the midst of an opioid epidemic. In 2012 alone there were approximately 259 million prescriptions written by primary care providers for opioids painkillers. The U.S. Center for Disease Control (CDC) now has new guidelines and recommendation due to the opioid analgesic epidemic. Education has been found to raise provider awareness and, subsequently, has decreased opioid use. Provider education helps with reinforcing the short-term use of opioids and adjunctive therapies and helps reinforce the idea of an individualized treatment plan for patients. Purpose: The purpose of this intervention is to increase provider education on opioid …

The Controversy Of Sexual Violence In The University Setting: Are College Athletes Given A Lighter Sentence Due To Their “Status”, Emma Weber

Honors College Theses

The following paper investigates sexual violence on university campuses. It discusses the role of the Title IX of the Education Amendments of 1972 along with a Dear Colleague Letter enacted by the United States’ federal government to all public institutions regarding how to respond when complaints and allegations of sexual violence are made. The paper addresses the statistics and common misconceptions surrounding sexual violence on college campuses before focusing specifically on student-athletes’ involvement in sexually violent crimes. It then looks into three highly publicized cases where student-athletes are the alleged perpetrators of sexual violence. The three cases analyzed are: the …

The Effects Of Implementing A Smartphone Application To Improve Asthma Self-Management In Adults, Lindsay J. Humpfer

Evidence-Based Practice Project Reports

Asthma is one of the most common chronic diseases, affecting 20.4 million adults in the United States (CDC, 2018). While asthma can generally be controlled, patients having an exacerbation may experience missed days of work and school, limitations in daily activities, decreased enjoyment of life, and decreased productivity at home, work, and school (MarcanoBelisario et al., 2013). Therefore, the purpose of this project was to improve patients’ overall asthma control and asthma-related quality of life by encouraging self-management through patient education and the implementation of a mobile smartphone application. A total of 26 adult primary care patients with asthma participated …

The Mandala As Response Art: A Method For Centering, Containing, And Exploring, Kristine Lorentzsen

Expressive Therapies Capstone Theses

This thesis examined research that explored the unique characteristics of art made within a circle—a form also known as the mandala. In addition, studies that researched the effects of mandala making on a variety of mental health conditions and as a diagnostic or assessment tool were reviewed. The results of this review suggest that the mandala art form has distinctive qualities, which may be beneficial in a variety of treatment settings. These findings were considered in relation to the practice of response art—art made by the art therapist in response to clinical work. Literature examining the effects of response art …

Prevention Of Oral Mucositis In Cancer Patients, Patricia E. Biel

Evidence-Based Practice Project Reports

Oral mucositis [OM] is one of the most severe non-hematological problems related to cancer treatments and can impact quality of life. It is linked to poorer outcomes due to the associated weight loss, pain, dehydration, and risk of developing life-threatening infections. The purpose of this evidence-based practice project was to determine if OM is preventable with the use of an oral care protocol and zinc supplementation when compared to use of oral care protocols alone. The Johns Hopkins Nursing Evidence-Based Practice Model was used to guide project implementation in an outpatient oncology office. Recommendations were developed from an exhaustive review …

Effects Of Therapeutic Music On Improving Depressive Symptoms Among Long-Term Care Facility Residents, Yi Jin

Evidence-Based Practice Project Reports

Depression is a common mental disorder that can contribute to both physical and psychological suffering (Skinner, 2014). The prevalence rate of depression is especially high among long-term care facility residents (CounsultGeri, 2018; Lolk & Andersen, 2015). The purpose of this EBP project was to establish a protocol incorporating therapeutic music as an adjunct therapy for managing depressive symptoms among residents of a long-term care facility in the Midwest. Roy adaptation model (Roy, 2009) was utilized as the theoretical framework, and the model for evidence-based practice change (Rosswurm & Larrabee, 2009) guided the project implementation. A total of 13 subjects were …