Medicine and Health Sciences Commons^™

A Comparison Of Quadriceps -To-Hamstrings Ratios During Isokinetic Testing, Cutting, And Drop Landings In Male Soccer Players, Shane R. O'Donnell, Jenevieve L. Roper

Honors Thesis

Collegiate soccer is not an unusual place to suffer a knee injury. The sport has many dynamic movements, such as cutting, jumping and shooting. Many professionals use quadriceps-to-hamstring (Q/H) ratios as a tool to determine when an injured player can to return to game play or use the ratio to investigate how predisposed a certain player is to sustaining a knee injury. However, many of these ratios are taken in isokinetic testing in a controlled environment and to our knowledge it is unknown if these ratios are similar to those measured during dynamic activity. Therefore, this study investigated if there …

Utilizing Quantitative Fluorescence Microscopy To Study Oncogenesis, Ellen Walford Hatch

Biomedical Sciences ETDs

Quantitative fluorescence microscopy is a highly technical, swiftly evolving field of methodologies that are uniquely able to probe the nano-scale biological environment. With these optimized, advanced technologies available, scientists and medical providers are equipped to illuminate a plethora of puzzles in science and medicine through the multiplexing and high spatiotemporal resolution offered. Here I first exploit these capabilities to study a rare cancer with multiplex immunohistofluorescence (IHF) to confirm cell type and undocumented protein expression that may have implications for our understanding of the biology of mast cells and the potential efficacy of treatment and symptom management in mast cell …

Auditory Verbal Hallucinations In Schizophrenia, Katherine Joiner

Honors Theses

The primary auditory cortex being linked to the AVHs could be due to it being overly sensitive when being stimulated by processing found internally, opposing to outward stimulation. The 173 individuals who were available for both structural data and resting state, 83 were found to have schizophrenia or schizoaffective. Resting state echo planar image (EPI) volumes had 32 slices of 4mm 64x64 matrix with 4mm thickness (voxel size = 3x3x4mm), with repetition time (TR) of 2000ms and echo time (TE) of 29ms. A total of 150 volumes (5 minutes) were used in the analysis. The auditory cortex in the SZ …

A Comprehensive Examination Of University Of Mississippi Early Entry Students’ Perceptions Of Mental Illness, Brianna Gray

Honors Theses

Mental disorders affect nearly 1 in 5 adults in the United States in a given year, and that number is steadily increasing. Pharmacists, being some of the most accessible and frequently contacted health care professionals, must be prepared to provide support for these patients. They can play a key role in whether or not there is a positive patient outcome. Education can play a role in pharmacists’ comfort with and knowledge of mental illness. The primary objective of this study was to determine if University of Mississippi early-entry pharmacy students’ mental illness knowledge, familiarity, and acceptable social distance affected their …

“I Do Have A Softer Side”: A Phenomenological Investigation Of The Prisoner-Dog Relationship In The Canine Partners For Life Training Program, Kathleen Kocherzat

Electronic Theses and Dissertations

This qualitative study investigated the relationship between incarcerated dog handlers and the service dogs they trained. Six men at a large northeastern prison were interviewed during the summer of 2017; all were current or former dog trainers in the Canine Partners for Life (CPL) training program. The men were serving prison sentences ranging anywhere from several years to life without parole. The interviews focused on their lived experience, rasing and training puppies for a period up to eighteen months. The qualitative data consisted of approximately thirteen hours of transcribed interviews, which were then interpreted using the phenomenological psychological method developed …

Precision Medicine And It's Ethical And Social Implications: Public Health And Gobal Persepctives, Evangel Sarwar

Electronic Theses and Dissertations

Ever since President Obama's launch of the Precision Medicine Initiative (PMI) in 2015, precision medicine (PM) has been anticipated as the new paradigm for healthcare with the capacity to “empower patients, researchers, and providers to work together toward the development of individualized care,” through research, technologies, and policies (President Obama, 2015). Precision Medicine (PM), in the form of genomics, offers unprecedented promise of providing new tools for improving health and reducing the burden of diseases, not just for the U.S. - but also globally. According to World Health Organization, genomics research and precision medicine will play a major part in …

Depression Screening In The Primary Care Setting, Colleen Dostal, Stephanie Boerding

Doctor of Nursing Practice Projects

Recent data reveals that approximately 17.3 million adults in the US population experience an episode of depression each year. Unidentified and untreated depression has many consequences leading to a poor quality of life, direct and indirect healthcare cost-related increases, and an increase in medical comorbidities. The U.S. Preventative Services Task Force recommends that all adults be screened for depression. The PHQ-2 and PHQ-9 are the most widely accepted screening tools in the preliminary detection of depression. The purpose of this project was to educate health care professionals regarding depression and the implementation of a new depression screening protocol: A positive …

Managing Chronic Back Pain In A Rural Primary Care Setting, Cassandra Chambers, Kaitlin E. Behnken

Doctor of Nursing Practice Projects

Chronic back pain management is complex and is often challenging for Primary Care Providers (PCPs). Rural PCPs are managing chronic back pain despite limited training and availability of pain management specialists. Pharmacological interventions are often used to treat chronic back pain despite current evidence suggesting physical therapy and aquatic therapy are first-line treatments. A directory of local therapy facilities offering physical and aquatic therapy and a review of clinical practice guidelines (CPG) were provided to three PCPs in a rural clinic in the Midwest. Use of the directory and the CPG was intended to help decrease reliance on pharmacological options …

Ethical Considerations In Short Term Global Health Experiences, Sheri Compton-Mcbride

Doctor of Nursing Practice Projects

Academically sponsored, short-term experiences in global health care (STEGH) have increased in popularity and accessibility among students originating from high-income countries (HIC) and enrolled in medical and health care programs. The populations served have socioeconomic, cultural, and/or geographic barriers to healthcare. Establishment of goals, clarity of expectations, and ethical awareness of services being provided are essential to achieve mutually agreeable outcomes for all involved. The project was designed to increase the knowledge of undergraduate nursing students scheduled to embark on a short term experience in global health. Module development and dissemination of evidence regarding the ethics of care and cultural …

Implementation Of A Medication Near-Miss Reporting System, Jamie Deubel

Doctor of Nursing Practice Projects

Faculty from a state university nurse anesthesia program requested a system to track medication near-miss events among their students. After a literature review, and in collaboration with faculty stakeholders, an electronic medication near-miss reporting system was developed and activated. A Likert scale evaluation survey was designed and reviewed by experts. This medication near-miss survey was auto-populated for all students who utilized the system. Students were happy with the anonymity, ease of use, and time it took to report the near-miss. Faculty stakeholders were given an open-ended question survey and results indicated faculty were pleased with the data they received. After …

Introducing Enhanced Recovery After Surgery For Colorectal Procedures: Development Of An Enhanced Recovery After Surgery Protocol, Vincent Compton

Doctor of Nursing Practice Projects

Abstract

The prevalence of colorectal surgery is increasing due to the surgical demand of an aging population with various comorbidities (Ralph & Duff, 2017). Consequences include an increased burden on clinical and financial resources from perioperative costs, length of stay (LOS), complications, and readmissions (Nelson et al., 2016). Enhanced recovery programs were created to improve patient outcomes and decrease financial strain. Objectives of this practice project included researching current evidence-based literature to determine the effectiveness of ERAS implementation in open and laparoscopic colorectal procedures, developing a customized ERAS protocol, and introducing the pathway to members of anesthesia, pharmacy, and the …

Unraveling Sex Trafficking Through Screening And Referrals, Rebecca Sarabia

Doctor of Nursing Practice Projects

Abstract

Human trafficking is a form of modern-day slavery; sex trafficking is one form of human trafficking. Previous research has demonstrated that most trafficking victims encounter the healthcare system at some point during their trafficking experience. Patients who have been sex trafficked may experience profound psychological and physical trauma. Healthcare personnel are in key positions to screen for trafficking and to provide appropriate referrals; if an awareness of the problem exists. The purpose of this project was to increase OB/Gyn office staff confidence with sex trafficking screening and to complete appropriate referrals to address the identified needs. The project began …

Improving Acute Pain Management For Pediatric Patients: Development Of A Ketamine Infusion Protocol, Oksana Koeppen

Doctor of Nursing Practice Projects

Multimodal analgesia is a recommended approach for acute pain management for adults and children (ASA, 2012; Chou et al., 2016). This approach is becoming a prominent modality in pain control strategies in the pediatric population. An intravenous anesthetic, ketamine, may be a useful adjunct for acute pain management in children. Development of a pediatric ketamine infusion protocol and its subsequent introduction to the key stakeholders at the host facility in central Illinois were the focus of this project. Research has demonstrated the effectiveness of low-dose intravenous ketamine in acute pain management when used as an adjunct to other medications (Asadi …

Clinical Guideline Based Interventions To Increase Smoking Cessation Success In Primary Care, Chloe Marth

Doctor of Nursing Practice Projects

Current evidence indicates that providers play an integral role and are most successful in improving cigarette smoking cessation rates through a combination of counseling, patient follow up, and pharmacotherapy. In order to address high smoking rates among patients at a primary care clinic in an urban community, the Five A’s model for smoking cessation (Ask, Advise, Assess, Assist, and Arrange) was initiated. During clinic visits, patients were asked about their smoking status. For those who stated they smoked cigarettes, further evaluation was conducted using the Fagerstrom Test for Nicotine Dependence and the patient’s willingness to quit was assessed. Five of …

Supraclavicular Blocks For The Treatment Of Distal Injuries In The Upper Extremity In The Emergency Department, Patrick O'Brien

Doctor of Nursing Practice Projects

Opioid addiction in the United States has increased, and interventions needs to be put into place to manage pain with fewer opioids. Alternatives like peripheral nerve blocks can be used to aid in pain management for acute injuries like ankle and wrist fractures. The purpose of this project is to develop and create a regional anesthesia protocol for acute upper and lower extremity fractures in the emergency department (ED) at Passavant Hospital in Jacksonville, Illinois, with the long-term goal of a reduction in opioid administration. An educational Power Point presentation was provided for the ED and the anesthesia personnel on …

Heart Failure Knowledge Among Cnas In A Skilled Nursing Facility: A Pilot Project, Amanda Mcdannald

Doctor of Nursing Practice Projects

Heart failure (HF) is one of the leading causes of hospitalization among patients over the age of 65 years. Many are transitioned to skilled nursing facilities (SNF) following hospital discharge. HF-specific SNF staff education was designed for early detection of changes and improved management of this patient population. Computer-based education modules and hands on skill demonstration stations were created to provide basic HF knowledge and specific guideline recommended care measures for the SNF environment. A pretest, post-test, and skill demonstration were implemented and included weight assessment, application of compression stockings, volume status monitoring, and low sodium diet recommendations. Pretest scores …

Utilizing Team-Based Care To Improve Rural Cardiovascular Care, Amanda Clouser, Kastin Engeling, Kris Rhodes

Doctor of Nursing Practice Projects

Cardiovascular morbidity and mortality are significantly higher among individuals living in rural areas compared to urban and suburban settings. Some contributing factors include financial limitations, education level, and limited access to cardiovascular specialty healthcare. Using a team-based cardiovascular care approach in rural communities, including both nurse practitioners and physicians, could help improve access to cardiovascular health services. The purpose of this project was to conduct a focus group interview to evaluate a team-based care approach to cardiovascular services implemented in a rural clinic located in a medically underserved area. Based on the results of the focus group interview, an evidence …

Improving Emergence And Awaken Time In The Obese Population: Development Of A Desflurane Protocol In The Obese Population, Nikki Watson

Doctor of Nursing Practice Projects

Studies have shown that obese patients are at an increased risk for apnea and aspiration during the postoperative period due to comorbidities associated with obesity (Nason, 2015). Complications such as apnea and aspiration can increase the length of stay in the post-operative care unit (PACU). Slower emergence further increases the risk for apnea and aspiration because of delayed return of protective reflexes (Brousseau, Dobson, & Milne, 2014). Evidence-based research has shown Desflurane to have the fastest wake-up times in obese patients when compared to Sevoflurane, Isoflurane, and Propofol (Juvin, Vadam, Malek, Dupont, Marmuse, & Desmonts, 2000). The goal of this …

Popliteal Blocks For The Treatment Of Distal Injuries In The Lower Extremity In The Emergency Department, Jacob Turner

Doctor of Nursing Practice Projects

Opioid addiction in the United States has increased, and interventions needs to be put into place to manage pain with fewer opioids. Alternatives like peripheral nerve blocks can be used to aid in pain management for acute injuries like ankle and wrist fractures. The purpose of this project is to develop and create a regional anesthesia protocol for acute upper and lower extremity fractures in the emergency department (ED) at Passavant Hospital in Jacksonville, Illinois, with the long-term goal of a reduction in opioid administration. An educational Power Point presentation was provided for the ED and the anesthesia personnel on …

Hand-Off Tool Implementation In Post-Anesthesia Care, Benjamin Nash

Doctor of Nursing Practice Projects

The issues surrounding the safety of patients and improving patient care outcomes in the pre-operative and post-operative environment, is one of ongoing focus and development. Post-operative, hand-off report is one aspect in the continuity of patient care that has affected patient outcomes. Clear, concise, and accurate communication concerning patients and their postoperative status is one way that providers and caregivers may ensure patient safety. There are many various organizations that emphasize the importance of clear, effective communication, in the form of a standardized hand-off tool to maximize patient safety. The purpose of the project was to standardize clear, concise, effective …

Implementing An Enhanced Recovery After Surgery Protocol In A Critical Access Hospital, Joseph Grazaitis

Doctor of Nursing Practice Projects

Enhanced recovery after surgery (ERAS) protocols provide numerous benefits for patients undergoing colorectal surgery. The goal of the protocol is to decrease surgical complications, patient’s length of hospital stay, recovery time, and increase patient satisfaction. The purpose of this doctoral project was to create and implement an ERAS protocol for a 25-bed critical access hospital. The findings obtained from the literature review were presented to the multi-disciplinary team. The specific needs of the surgical team were identified, and the ERAS protocol was created. Lastly, the ERAS protocol was finalized and implemented in the institution. The outcome measures examined were the …

Improving Perioperative Warming Of Surgical Patients: Implementation Of A Warming Protocol, Maghy Schrage

Doctor of Nursing Practice Projects

Despite the ample amount of knowledge and interventions available to keep patients warm in the operating room, the issue of inadvertent perioperative hypothermia continues to be a problem affecting surgical patients. Unfortunately, even a mild degree of hypothermia can increase a patient’s chance for negative outcomes such as surgical site infections, bleeding, and higher risk for mortality. The project involved development of a warming protocol/guideline for a small community hospital. The implementation process consisted of two separate presentations tailored to educate both nursing and anesthesia staff about the importance of warming patients, reimbursement initiatives, and appropriate interventions.

The project study …

Improving Allergy Immunotherapy Adherence, Amy Branham

Doctor of Nursing Practice Projects

Allergen Immunotherapy (AIT) is an effective treatment for allergic rhinitis. However, at a Midwest teaching clinic, patients tend to not complete the entire course of immunotherapy. AIT adherence is suboptimal due to a multitude of reasons. The purpose of this project is to increase adherence to AIT by implementing the following evidence based interventions; a text message reminder, a communication/education template, and through increasing clinic accessibility. Initial implementation involved working with clinic personnel to develop the content of the reminder texts and of additional educational materials. Subsequently, the changes were executed at the beginning of fall. Over the following three …

Adequate Pain Control With Ofirmev To Minimize Narcotics Consumption And Its Side Effects, Gideon Nkrumah

Doctor of Nursing Practice Projects

Typically, perioperative pain has been managed with opioids, however, the extreme use of opioids has been associated with respiratory depression, excessive sedation, drowsiness, nausea, vomiting, ileus, severe constipation, prolonged hospital stay, addiction, and dependence. The American Society of Anesthesiologists Task Force on Acute Pain Management recommends that patients should always receive non-opioid analgesics like Acetaminophen and NSAIDs as first-line agents so that opioids can be used as adjunctive agents to minimize opioid-related side effects, addiction, and dependence (The American Society of Anesthesiologists, 2011).

A protocol was developed to help providers use Ofirmev effectively and efficiently. The goals of this project …

Implementation Of Crisis Checklists In The Operating Room, Gregory S. Feilner

Doctor of Nursing Practice Projects

Background: Operating room crises require prompt, efficient action to avoid detrimental outcomes. Research shows that crisis checklists or other cognitive aids assist anesthesia providers in taking prompt action while improving efficiency by decreasing treatment steps missed during critical events.

Objectives: The purpose of this project was to evaluate the effectiveness of incorporating cardiac arrest and malignant hyperthermia crisis checklists into the operating room using high-fidelity simulation-based education.

Methods: Researchers implemented the Stanford Emergency Manual Cognitive Aids for cardiac arrest and malignant hyperthermia to anesthesia staff at a community hospital in southern Illinois with 18 participants. Implementation consisted of an education …

Utilizing Simulation To Implement Cognitive Aids In The Operating Room, Kaitlyn Brown

Doctor of Nursing Practice Projects

Background: Operating room crises require prompt, efficient action to avoid detrimental outcomes. Research shows that crisis checklists or other cognitive aids assist anesthesia providers in taking prompt action while improving efficiency by decreasing treatment steps missed during critical events.

Objectives: The purpose of this project was to evaluate the effectiveness of incorporating cardiac arrest and malignant hyperthermia crisis checklists into the operating room using high-fidelity simulation-based education.

Methods: Researchers implemented the Stanford Emergency Manual Cognitive Aids for cardiac arrest and malignant hyperthermia to anesthesia staff at a community hospital in southern Illinois with 18 participants. Implementation consisted of an education …

Perceptions And Experiences Of Skilled Birth Attendants On Using A Newly Developed Strap-On Electronic Fetal Heart Rate Monitor In Tanzania, Sara Rivenes Lafontan, Hussein Kidanto, Hege L. Ersdal, Columba Mbekenga, Johanne Sundby

School of Nursing & Midwifery, East Africa

Background: Regular fetal heart rate monitoring during labor can drastically reduce fresh stillbirths and neonatal mortality through early detection and management of fetal distress. Fetal monitoring in low-resource settings is often inadequate. An electronic strap-on fetal heart rate monitor called Moyo was introduced in Tanzania to improve intrapartum fetal heart rate monitoring. There is limited knowledge about how skilled birth attendants in low-resource settings perceive using new technology in routine labor care. This study aimed to explore the attitude and perceptions of skilled birth attendants using Moyo in Dar es Salaam, Tanzania.

Methods: A qualitative design was used to collect …

Perceptions Of Parents And Religious Leaders Regarding Minimal Invasive Tissue Sampling To Identify The Cause Of Death In Stillbirths And Neonates: Results From A Qualitative Study, Anam Shahil Feroz, Mohsina Noor Ibrahim, Elizabeth M. Mcclure, Anum Shiraz Ali, Shiyam Sunder Tikmani, Sayyeda Reza, Zahid Abbasi, Jamal Raza, Haleema Yasmin, Khadija Bano, Afia Zafar, Sameen Siddiqi, Robert L. Goldenberg, Sarah Saleem

Community Health Sciences

Background: Recently, the minimal invasive tissue sampling (MITS) procedure has been developed to support determination of the cause of death as an alternate to conventional autopsy, especially in countries where complete diagnostic autopsy is not routine. To assess the feasibility of implementation of the MITS procedure for a study to determine cause of death in premature births and stillbirths in south Asia, we explored the views and perceptions of parents and religious leaders on the acceptability of MITS.
Methods: A qualitative study was conducted at the National Institute of Child Health (NICH) hospital of Karachi, Pakistan. Focus group discussions (FGDs) …

Neurotoxic Effects Of Hiv-1 Gp120 And Interaction With Allopregnanolone, Kimberly A. Thornton

Honors Theses

With increasing incidence of HIV and its associated neurocognitive disorders, there has emerged a need for an antiviral with improved delivery to the CNS. In searching for drug candidates that meet these criteria, some have noted that certain steroid hormones like estrogen and progesterone that naturally accumulate in the CNS show neuroprotective effects in cells exposed to HIV proteins. This investigation focused on testing the potential protective effects of the progesterone metabolite, allopregnanolone (AlloP), against HIV protein gp120-mediated neurotoxicity. Experiments were conducted using SH-SY5Y neuroblastoma cells that were exposed to varying concentrations of AlloP (0-100 nM) in conjunction with one …

Early Identification And Intervention In Patients With Atrial Fibrillation Using An Implantable Cardiac Monitor To Significantly Improve Guideline-Based Anticoagulation Therapy In An Outpatient Cardiology Clinic, Lisa Alvarez

Dissertations

The purpose of this research was to (a) examine the demographics of patients receiving care in an outpatient cardiology clinic, (b) describe the relationship between the atrial fibrillation (AF) and other variables (e.g., BMI), (c) examine the frequency and the length of time to AF diagnosis in patients implanted with an implantable cardiac monitoring (ICM) device, (d) observe provider patterns of treatment with oral anticoagulants (OACs), and (e) investigate documented considerations to either diagnose or rule out OSA in a group of outpatient AF patients in a cardiology clinic.

Background: AF is largely undiagnosed but can cause major morbidity and …