Medicine and Health Sciences Commons^™

Occurrence Of Natural Vertical Transmission Of “Zika Like Virus” In Aedes Aegypti Mosquito In Jambi City, Tri Baskoro Satoto, Nur Alvira Pasca Wati, Wida Purwaningsih, Hari Kusnanto Josef, Purwono Purwono, Rumbiwati Rumbiwati, Hermanto Hermanto, Roger Frutos

Kesmas

Zika virus can be transmitted through mosquitoes such as Aedes aegypti and Ae. albopictus. During the transition period of 2014–2015, an outbreak of dengue was reported in Jambi City, during which several sufferers were screened positive for Zika virus infection by the Eijkman Institute. It was interesting to note that all of those positive for Zika virus infection were indigenous residents and none of them had a history of international travel. This descriptive analytic study with a cross-sectional design study was conducted to present an overview of Aedes spp. population using ovitrap and egg colonization methods and to detect the …

Factors Related To Adolescent Behavior Towards Hiv/Aids Prevention, Yuliasti Eka Purnamaningrum, Ratyas Ekartika Puspita Candra Nugrahawati, Munica Rita Hernayanti, Anne Vajee

Kesmas

In 2016 Special Region of Yogyakarta was ranked 9th as the province with the highest number of people suffered from HIV/AIDS especially at Sleman regency. Globally, AIDS was the second leading cause of adolescents’s death aged of 10-19 years. The purpose of this study was to find out factors affecting the behaviour of the adolescents towards HIV/AIDS prevention. This research using with cross sectional study design. The sampling technique which used was stratified random sampling resulted in 59 respondents from 11th grade students at SMA Negeri 2 Sleman were selected as sample. Data were collected using questionnaire and analyzed using …

The Use Of Geospatial Modeling And Novel Diagnostics To Detect And Map Risk Factors Of Soil-Transmitted Helminths In Feira De Santana, Brazil, Ryan Harry Avery

LSU Doctoral Dissertations

Soil-transmitted helminth (STH) infections impact billions of people worldwide. The traditional STH control approach is a morbidity control strategy implementing mass drug administration (MDA) programs targeting school-aged children (SAC). In Brazil, this control strategy has decreased STH prevalence to less than 20% in most of the country and providing an opportunity to transition from the morbidity control program and towards a surveillance and response system geared towards STH elimination. Surveillance and response systems geared towards elimination require the implementation higher accuracy diagnostics to detect infection in low-transmission communities, surveillance of entire households, high-resolution modeling at the household-habitat scale, and targeted …

Local Electronic Structure Of The Peptide Bond Probed By Resonant Inelastic Soft X-Ray Scattering, L. Weinhardt, A. Benkert, F. Meyer, M. Blum, D. Hauschild, R. G. Wilks, M. Bär, W. Yang, M. Zharnikov, F. Reinert, C. Heske

Chemistry and Biochemistry Faculty Research

The local valence orbital structure of solid glycine, diglycine, and triglycine is studied using soft X-ray emission spectroscopy (XES), resonant inelastic soft X-ray scattering (RIXS) maps, and spectra calculations based on density-functional theory. Using a building block approach, the contributions of the different functional groups of the peptides are separated. Cuts through the RIXS maps furthermore allow monitoring selective excitations of the amino and peptide functional units, leading to a modification of the currently established assignment of spectral contributions. The results thus paint a new-and-improved picture of the peptide bond, enhance the understanding of larger molecules with peptide bonds, and …

Variables Associated With Successful Vascular Access Cannulation In Hemodialysis Patients: A Prospective Cohort Study, Linda L. Coventry, Jon M. Hosking, Doris T. Chan, Evelyn Coral, Wai H. Lim, Amanda Towell-Barnard, Diane E. Twigg, Claire M. Rickard

Research outputs 2014 to 2021

BACKGROUND: Successful vascular access (VA) cannulation is integral to the delivery of adequate dialysis, highlighting the importance of ensuring the viability of arteriovenous access in hemodialysis (HD) patients. Missed VA cannulation can lead to infection, infiltration, hematoma or aneurysm formation resulting in the need for access revision, central venous catheter (CVC) placement, or permanent loss of VA. Cannulation-related complications can also negatively impact on a patient's dialysis experience and quality of life. This study aimed to identify patient, VA and nurse factors associated with unsuccessful VA cannulations.

METHODS: A prospective cohort study was conducted in HD patients with a permanent …

Patient-Specific Dendritic Cell Vaccines With Autologous Tumor Antigens In 72 Patients With Metastatic Melanoma., Robert O Dillman, Andrew N Cornforth, Edward F Mcclay, Carol Depriest

Articles, Abstracts, and Reports

Aim: Metastatic melanoma patients were treated with patient-specific vaccines consisting of autologous dendritic cells loaded with antigens from irradiated cells from short-term autologous tumor cell lines.

Patients & methods: A total of 72 patients were enrolled in a single-arm Phase I/II (NCT00948480) trial or a randomized Phase II (NCT00436930).

Results: Toxicity was minimal. Median overall survival (OS) was 49.4 months; 5-year OS 46%. A 5-year OS was 72% for 18 recurrent stage 3 without measurable disease when treated and 53% for 30 stage 4 without measurable disease when treated. A total of 24 patients with measurable stage 4 when treated …

Exploratory Qualitative Study To Understand The Underlying Motivations And Strategies Of The Private For-Profit Healthcare Sector In Urban Bangladesh, Alayne Mary Adams, Rushdia Ahmed, Tanzir Ahmed Shuvo, Sifat Shahana Yusuf, Sadika Akhter, Iqbal Anwar

Faculty Publications

Objectives This paper explores the underlying motivations and strategies of formal small and medium-sized formal private for-profit sector hospitals and clinics in urban Bangladesh and their implications for quality and access.

Methods This exploratory qualitative study was conducted in Dhaka, Sylhet and Khulna City Corporations. Data collection methods included key informant interviews (20) with government and private sector leaders, in-depth interviews (30) with clinic owners, managers and providers and exit interviews (30) with healthcare clients.

Results Profit generation is a driving force behind entry into the private healthcare business and the provision of services. However, non-financial motivations are also emphasised …

Adiposity Mediates The Association Between The Dietary Inflammatory Index And Markers Of Type 2 Diabetes Risk In Middle-Aged Black South African Women, Asanda Mtintsilana, Lisa K. Micklesfield, Elin Chorell, Tommy Olsson, Nitin Shivappa, James R. Hebert, Andre P. Kengne, Julia H. Goedecke

Faculty Publications

The dietary inflammatory index (DII^®), a validated tool used to measure the inflammatory potential of the diet, has been associated with metabolic disorders in various settings, but not in African populations. The aim of this study was to investigate whether the DII is associated with markers of type 2 diabetes (T2D) risk, and if this association is mediated by adiposity and/or low-grade inflammation, in black South Africa women. Energy-adjusted-DII (E-DII) scores were calculated in 190 women (median age, 53 years) from the Birth-to-Twenty plus cohort using a validated food frequency questionnaire. Fasting glucose, insulin, HbA1c, and inflammatory cytokines …

2019 Graduate Medical Education Research Day Compendium, Unlv School Of Medicine

Graduate Medical Education Research Day Compendium

Anyone engaged in research knows that the process can be daunting. Add the rigors of training in a graduate medical education program to this, and it might seem all but impossible to accomplish anything meaningful. However, the individuals highlighted in our 2019 Graduate Medical Education Research Day Compendium were able to overcome those odds. Their abstracts are showcased here and their efforts to advance the collective knowledge in their respective fields are commendable. We thank these Resident and Fellow Physicians and all who have supported them in their endeavors to reach this point with their research. Most of all, we …

Implementation Of An Evidenced-Based Concussion Management Protocol Utilizing Telemedicine In A Student Health Center, Shelly Benfield

Doctor of Nursing Practice Final Manuscripts

Background: An estimated 3.8 million concussions occur yearly in the United States and the incidence of youth concussions is on the rise. If untreated or unrecognized, more serious complications of concussions include post-concussion syndrome, second impact syndrome, and chronic traumatic encephalopathy. Clinic leadership in a southern California student health center identified systematic inefficiencies and noted a lack of standardized follow-up concussion appointment times which resulted in decreased clinic efficiency.

Purpose: The purpose of this evidenced-base project was to implement an effective concussion protocol and follow-up treatment plan that would improve clinic efficiency without negatively impacting concussion outcomes.

Evidence-based Interventions: A …

Laryngeal Preservation Strategies In Locally Advanced Laryngeal And Hypopharyngeal Cancers., Athanassios Argiris, Jean Louis Lefebvre

Department of Medical Oncology Faculty Papers

For long, the treatment of locoregionally advanced laryngeal and hypopharyngeal squamous cell cancers (SCC) consisted of either total laryngectomy (TL) or definitive radiotherapy (RT). The development of induction cisplatin plus 5-fluorouracil (PF) and the correlation between chemosensitivity and radiosensitivity in previously untreated patients opened a new era of treatment aiming at laryngeal preservation (LP). The fundamental concept was to employ induction PF in order to select patients for subsequent treatment with either TL or RT according to tumor response to PF. The first two trials (VALGSG for laryngeal SCC and EORTC 24891 for hypopharyngeal SCC) concluded that such an approach …

Recovery And Person-Centered Care In Gambling Disorder, Angels Gonzalez-Ibanez Phd In Psychology, Adjunct Professor

International Conference on Gambling & Risk Taking

No abstract provided.

Investigating The Benefits Of Virtual Reality On Student Acquisition Of 3d Anatomical Information, Dr. Kevin Flaherty, Juliana Pinheiro, Benjamin Karger

Celebration of Learning

Virtual reality (VR) technology is becoming more accessible within educational settings due to price decreases and greater software availability. VR is particularly useful for teaching anatomy, as students often struggle to learn the three-dimensional relationships between body structures from two-dimensional images in textbooks. Using funds from Augustana’s Pedagogy and Technology Grant, we purchased and assembled a VR workstation and began researching the effectiveness of VR in anatomy education. The early results of this research show that students exhibited substantial increases in their knowledge anatomical structures and their ability to reconstruct the three-dimensional relationships between anatomical structures after 30 minutes using …

The Association Between Herpes Simplex Virus Type 1 Reactivation And Alzheimer’S Disease, Andrew Allee

BIO 410 Spring 2019 Research Papers

This review will focus on the interaction of herpes simplex virus type 1 (HSV-1) and its causative role in pathogenesis of Alzheimer’s disease (AD) noting specifically, the epidemiological relevance of addressing this problem, as well as the molecular pathways associated. HSV-1 reactivation tends to be one of the primary causative events that is responsible for many of the pathologies associated with AD, such as: amyloid beta (Aβ) accumulation caused by malfunctioning cleavage of amyloid precursor protein (APP) as well as tau hyperphosphorylation. HSV-1 reactivation is a primary causative event in downstream dysfunction and is also shown to be directed by …

Neuroscience Journal Club Neu 460, Joanna Burkhardt

Library Impact Statements

No abstract provided.

An Assessment Of Irb Member Values Using The Irb Researcher Assessment Tool, Andrew Gerber

Theses and Dissertations

This study employed the IRB Researcher Assessment Tool (IRB-RAT) to better understand values held by IRB members at Rowan University, and piloted the use of the IRB-RAT in this institutional context. A sample of Rowan University IRB affiliates, including administrators and members (N = 11), provided ratings related to their "ideal" and "actual" IRB on this 45-item questionnaire, addressing eight areas of IRB performance. Analyses included mean calculations, calculations of mean difference, and comparisons to those provided in a national validation sample for the measure. Results indicated that, by comparison to a national validation sample, Rowan University IRB members tended …

Mapping Pps: A Case Study Of Story Map Journals For Interactive Health Reporting, Susan Rauch

Publications

A case study on the visual-material components of story map journals as visual, new media interactive health reporting used in population health surveillance. The story map journal is demonstrated an effective tool that visually reports, maps and tracks global support networks and health resources for post- polio (PPS) survivors.

Second-Harmonic Generation Microscopy Analysis Reveals Proteoglycan Decorin Is Necessary For Proper Collagen Organization In Prostate., Kirby R. Campbell, Rajeev Chaudhary, Monica Montano, Renato V. Iozzo, Wade A. Bushman, Paul J. Campagnola

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Collagen remodeling occurs in many prostate pathologies; however, the underlying structural architecture in both normal and diseased prostatic tissues is largely unexplored. Here, we use second-harmonic generation (SHG) microscopy to specifically probe the role of the proteoglycan decorin (Dcn) on collagen assembly in a wild type (wt) and Dcn null mouse (Dcn  -    /    -  ). Dcn is required for proper organization of collagen fibrils as it regulates size by forming an arch-like structure at the end of the fibril. We have utilized SHG metrics based on emission directionality (forward-backward ratio) and relative conversion efficiency, which are both related to …

Get Engaged: Results Of Ncpg 2018 National Survey Of Gambling Attitudes & Experiences, Keith Whyte, Don Feeney

International Conference on Gambling & Risk Taking

The National Survey of Gambling Attitudes and Gambling Experiences (NGAGE) is the largest published survey of gambling participation and problems in the US. This unprecedented look into how Americans gamble, what they gamble, how they think about it in every state. Includes a special focus on sports gambling. Presenters will review the findings and implications for everyone involved in gambling issues.

The Effect Of Caregiver Burnout On Alzheimer's Treatment Compliance, Daniel Kane, Brandon Liu

School of Psychology, Family, and Community Research Conference

According to the Alzheimer's Association (2019), approximately 5.8 million Americans live with Alzheimer's Disease (AD). Additionally, it is reported that 16 million Americans are considered caregivers to those individuals. While AD is incurable, treatment adherence is a significant predictor of family and patient outcomes. This proposal explores the impact of caregiver burnout on patient treatment compliance of those with Alzheimer's disease (AD). It is hypothesized that the presence of burnout in caregivers of loved ones with AD will negatively affect treatment compliance. A possible implication of this study is improving quality of life outcomes for those managing AD.

Mental Health Profiles Of Adolescents With Co-Occurring Gambling Behaviours And Benzodiazepine Misuse, Emilie Fletcher, Jeremie Richard, Jeffrey Derevensky Dr, William Ivoska Dr, Caroline Temcheff Dr

International Conference on Gambling & Risk Taking

No abstract provided.

Gender Differences In Non-Suicidal Self-Injury In A Sample Of Treatment-Seeking Gamblers, Megan Cowie

International Conference on Gambling & Risk Taking

Gambling Disorder (GD) is a public health concern with tremendous implications (Smith & Wynne, 2002). The disorder rarely occurs in isolation, often presenting with other conditions. Suicidal ideation and attempts are common among treatment-seeking gamblers (Maccallum & Blaszczynski, 2003). An important yet overlooked risk factor for suicidality is non-suicidal self-injury (NSSI; Klonsky et al., 2013). NSSI can serve many functions: relief of negative emotions; generation of positive states; escape from interpersonal obligations; attention or facilitation of resources (Nock & Prinstein, 2004). Previous research has found gender differences in NSSI. Despite NSSI’s relationship to suicidality and the noted gender differences, literature …

Chemotherapy Is Avoided During The First Trimester Of Pregnancy, When Is The Safest Time To Start Treatment During The Second Or Third Trimester?, Elyce Cardonick, Emily Eicheldinger, John P. Gaughan

Cooper Medical School of Rowan University Departmental Research

ABSTRACT

Background

Cancer occurs in approximately 1:1000 pregnancies. When chemotherapy cannot be delayed until postpartum, beginning chemotherapy is based on presumed safety after organogenesis is completed during the first trimester. The safest gestational age to start chemotherapy after the first trimester is unknown.

Patients and Methods

In an observational cohort of pregnant women diagnosed and treated for cancer at multiple centers, pregnancy outcomes for the mother, and clinical outcomes for the neonate were analyzed according to the gestational age in weeks of pregnancy at first chemotherapy cycle. Outcomes including birth weight, fetal growth restriction, congenital malformations, and perinatal complications for …

An Overview Of American Ginseng Through The Lens Of Healing, Conservation And Trade, Margaret Wulfsberg

Lawrence University Honors Projects

American ginseng (Panax quinquefolius) is an herbaceous plant found in the eastern United States and Canada. Due to the high demand for ginseng roots on the Chinese market, it has been harvested at unsustainable rates. If this continues, overharvest along with other environmental factors will lead it to become extinct in the wild. American ginseng became popular due to its similarities with Asian ginseng, (Panax ginseng), a related plant that has been used in Chinese medicine for hundreds of years. Since there is so little Asian ginseng left in the wild, American ginseng now helps satisfy …

Factors That Predict Lien Payouts, Viktoria Chudsky

Theses and Dissertations

The purpose of this research is to find ways to increase Medicaid collections in order to promote citizens’ access to government sponsored programs. This research paper is written to observe which variables increase reimbursement funds that will be reinjected into Medicaid and Public Assistance programs. The study looks at client and law firm characteristics such as the settlement amount, the client’s age, how long the case has been open in the MAESTRO system for, the client’s borough of residence, and the defending law firm’s location to identify if any of these characteristics influence the amount of recoupment. The firms’ names …

Illness And The American Workplace: Issues And Implications For Employers And Employees, Victoria R. Dolan

Student Theses and Dissertations

This project aims to identify American employee experiences and existing workplace policies and cultures surrounding illness, disability, and sick leave. This approach was taken in order to closely examine what looks to be working well for companies and workers, and what could benefit from a more human centric approach in regards to workplace policy and employee support programs. The study of employee experiences in particular represents a gap in the current scholarly literature regarding illness and illness policy in the American workplace, and more accurately represents the experiences for both employees and employers. Furthermore, it assists with distinguishing the types …

Use Of New Oral Anticoagulants In Preventing Ischemic Stroke In Patients With Atrial Fibrillation, Travis Hunt, Blaine Winters, Rod Newman

Student Works

Atrial fibrillation (AF) affects millions of Americans and puts them at increased risk for ischemic stroke. It is important for providers to recognize AF and know when it is appropriate to treat patients with anticoagulation. There are several options available for anticoagulation. Warfarin is the most widely used anticoagulant. Other alternatives to warfarin are new oral anticoagulants (NOACs) which are increasingly prescribed in recent years. It is vital providers know the differences between warfarin and NOACs, and what is the most appropriate anticoagulant to use for their patient with AF. The purpose of this paper is to review the clinical …

Female Family Members Lack Understanding Of Indeterminate Negative Brca1/2 Test Results Shared By Probands, Deborah Himes, Deborah K. Gibbons, Wendy C. Birmingham, Renea L. Beckstrand, Amanda Gammon, Anita Y. Kinney, Margaret F. Clayton

Faculty Publications

Genetic test results have important implications for close family members. Indeterminate negative results are the most common outcome of BRCA1/2 mutation testing. Little is known about family members’ understanding of indeterminate negative BRCA1/2 test results. The purpose of this mixed-methods study was to investigate how daughters and sisters received and understood genetic test results as shared by their mothers or sisters. Participants included 81 women aged 40-74 with mothers or sisters previously diagnosed with breast cancer and who received indeterminate negative BRCA1/2 test results. Participants had never been diagnosed with breast cancer nor received their own genetic testing or counseling. …

Technical Freediving: An Emerging Breath-Hold Diving Technique, Derek Covington, Robert H. Lee, Steven Toffel, Alberto Bursian, Kirk Krack, Chris Giordano

Journal of Human Performance in Extreme Environments

Technical freediving can be defined as freediving augmented by the use of oxygen-enriched gases or oxygen before, during, or after a freedive. As a result of these techniques, breath-hold divers can visit and enjoy underwater wrecks, reefs, and other diving locations previously located at depths unreachable to apnea divers. By pre-breathing oxygen-enriched gases in conjunction with hyperventilation—which decreases the partial pressure of carbon dioxide (PCO2)—the technical freediver now has additional oxygen to facilitate aerobic respiration during the dive. In addition, pre-breathing oxygen decreases tissue nitrogen tensions, which limits inert gas loading and decreases the risk of decompression sickness (DCS). Finally, …

Exploring The Impact Of Challenging Behaviors On Treatment Efficacy In Autism Spectrum Disorder, Juliana Hoag

Computational and Data Sciences (MS) Theses

The focus of this study was to explore the impact of challenging behaviors on Applied Behaviors Analysis treatment in Autism Spectrum Disorder. The prevalence of ASD is on the rise, so it is important that we understand how patients are responding to treatment. In this study, we cluster patients (N=854) based on their eight observed challenging behaviors using k-means, a machine learning algorithm, and then perform a multiple linear regression analysis to find significant differences between average exemplars mastered. The goal of this study was to expand the research in the area of ABA treatment for ASD and to help …