Medicine and Health Sciences Commons^™

“I Am A Runner”: A Qualitative Analysis Of Women-Runners’ Pregnancy Experiences, Jennifer M. Ohlendorf, Anna L. Anklam, Lindsay Gardner

College of Nursing Faculty Research and Publications

Background

Women runners are a group with potential for health maintenance and health promotion in pregnancy. When providers counsel women to discontinue or cut back on running without cause, an opportunity for health benefits to both woman and baby may be lost.

Aim

This study aims to explicate the experience women runners have in pregnancy to further providers’ understanding of this population’s unique needs.

Methods

An online, qualitative inquiry was employed to explore the experiences of an online community of women runners in pregnancy (N = 22). The Doing Pregnancy framework provided guidance for final stages of the analysis.

Findings …

Surgical Thrombectomy For Pulmonary Embolism: Updated Performance Rates And Outcomes, Fahad Alqahtani, Muhammad Bilal Munir, Sami Aljohani, Abdul Tarabishy, Ahmad Almustafa, Mohamad Alkhouli

The Texas Heart Institute Journal

Treatments for pulmonary embolism are numerous and often complex. Current data on surgical thrombectomy are important but are not readily available. We studied the National Inpatient Sample to evaluate trends in the performance rates and outcomes of surgical thrombectomy in the United States from 2003 through 2014. We think that our findings have meaningful application to the triage and risk stratification of patients who have hemodynamically significant pulmonary embolism.

Adam Christian Thebesius' Channels Into The Human Heart: The Thebesian Veins And The Thebesian Valve, Magdalena Mazurak, Jacek Kusa

The Texas Heart Institute Journal

In 1708, Adam Christian Thebesius, a 22-year-old student at Leiden University, presented his graduate thesis, Disputatio medica inauguralis de circulo sanguinis in corde. More than a doctoral dissertation, this groundbreaking work opened new channels into the study of the human coronary venous system. Thebesius' theory about the vascular communication between the coronary arteries and the chambers of the heart helped to advance understanding of hemodynamic principles and to clarify the physiologic pathways of the coronary circulation. The following article—the third in a trilogy about Lower Silesian scientists—provides an overview of the life story and achievements of this Silesian physician …

Incidence And Predictors Of Obstructive Coronary Artery Disease And The Role Of Cardiac Troponin Assays In Patients With Unstable Angina, Sushan Yang, Nirmanmoh Bhatia, Meng Xu, John A Mcpherson

The Texas Heart Institute Journal

In a time when cardiac troponin assays are widely used to detect myocardial injury, data remain scarce concerning the incidence and predictors of substantial obstructive coronary artery disease that causes unstable angina. This retrospective single-center study included consecutive patients hospitalized for unstable angina from January 2015 through January 2016. Patients with troponin I levels above the upper reference limit and those who did not undergo angiography were excluded. Multivariate logistic regression analysis was used to identify predictors of obstructive coronary artery disease that warranted revascularization and of major adverse cardiac events up to 6 months after discharge from the hospital. …

Endoanchors Minimize Endoleaks In Chimney-Graft Endovascular Repair Of Juxtarenal Abdominal Aortic Aneurysms, Edgar Luis Galiñanes, Eduardo A Hernandez-Vila, Zvonimir Krajcer

The Texas Heart Institute Journal

Juxtarenal abdominal aortic aneurysms (AAAs) are difficult to treat because they often have little or no proximal aortic neck. Patients with this complex anatomy are not usually candidates for an endovascular aneurysm repair (EVAR). Chimney-graft EVAR has been introduced, but type Ia endoleak is a typical risk. We have begun using EndoAnchors to determine whether this risk can be reduced. From July 2013 through July 2014, we used the chimney-graft EVAR technique in 5 patients whose juxtarenal AAAs had a short or no proximal aortic neck. During the procedure, we implanted EndoAnchors as needed. Postprocedurally, at 30 days, and through …

Arachidin 3 Modulation Of Lipid Metabolism In Rotavirus Infections, Stormey Wisdom

Electronic Theses and Dissertations

Rotavirus (RV) can cause severe and deadly gastroenteritis in young children, infants, and immunocompromised individuals. Previous studies have shown that arachidin 3 (A3) inhibits RV replication, and that RV replication is dependent on the presence of lipids. This study investigated the alteration of lipid metabolism by A3 in RV infected HT29.f8 cells. A decrease in the RV regulation of lipid biosynthesis genes was observed with the addition of A3 using qRT-PCR. Also, immunofluorescent and histochemical staining for neutral fats, a major component of cellular lipid droplets, revealed an increased accumulation with both RV and RV+A3 when compared to no virus …

J Mich Dent Assoc June 2019

The Journal of the Michigan Dental Association

Every month, The Journal of the Michigan Dental Association brings news, information, and features about Michigan dentistry to our state's oral health community and the MDA’s 6,200+ members across the state. No publication reaches more Michigan dentists! This month's issue features the 2019-20 MDA Continuing Education Catalog, and resources on avoiding human resources mistakes and protecting your dental office against cybercriminals.

E-Cigarette Chemistry And Analytical Detection, Robert M. Strongin

Chemistry Faculty Publications and Presentations

The study of e-cigarette aerosol properties can inform public health while longer-term epidemiological investigations are ongoing. The determination of aerosol levels of known toxins, as well as of molecules with unknown inhalation toxicity profiles, affords specific information for estimating the risks of e-cigarettes and for uncovering areas that should be prioritized for further investigation.

Interdisciplinary Collaboration Needed In Obtaining High-Quality Medical Information In Child Abuse Investigations, Elizabeth Cleek, Norah L. Johnson, Lynn K. Sheets

College of Nursing Faculty Research and Publications

Background

Despite reporting legislation, healthcare providers (HCPs) do not always report and collaborate in cases of suspected child abuse. Recognizing this leaves children at risk, the Wisconsin Child Abuse Network (WI CAN) sought to understand barriers to mandated reporting and collaboration with child abuse investigators.

Objective

The purpose of the study was to investigate barriers for professionals in providing and obtaining high-quality medical information in child abuse investigations.

Participants and setting

Participants included five discipline-specific focus groups: HCPs, child protective services (CPS), law enforcement, lawyers, and judges. All professionals had been directly involved in Wisconsin child abuse cases.

Methods

This …

The Generation Of Novel Metal-Folate- Phenanthroline Complexes And Phenanthroline-Folate Conjugates With Potential As Chemotherapeutic Agents, Aisling Crowley

Doctoral

The folate receptor (FR) was identified in 1986 and has been established as a ‘molecular Trojan Horse’ target for the uptake of folate-conjugated organic molecules into cells. The FR is overexpressed in many malignancies, including those of the ovary, uterus, breast, cervix, and prostate, yet it is reportedly under-expressed in normal healthy cells. This difference in expression and the high affinity/specificity of folate towards the folate receptor presents a promising drug delivery system. The aim of this research was to utilise folic acid as a targeting moiety and generate simple metal folate and novel folate-phenanthroline complexes with cytotoxic properties. A …

Prevalence Of Ametropia, Amblyopia And Visual Impairment In Schoolchildren In Ireland, Siofra Harrington

Doctoral

Background: Uncorrected refractive error is an avoidable cause of visual impairment (Naidoo et al., 2016). Currently, there is a lack of adequate data on eye and vision disorders in schoolchildren in Ireland. Accurate prevalence estimates of refractive error and vision disorders are necessary to determine their impact on public health and to assess the need for interventions (McCarty and Taylor, 2000). Purpose: This study reports the prevalence of ametropia, presenting visual impairment, amblyopia and provides population norms for ocular biometric measures in schoolchildren in Ireland. Links between refractive error and demographic and lifestyle factors were investigated. The impact of poor …

The Real Period Stain: Menstrual Stigma And Its Pressures In South Asia, Ila Mostafa

Celebration of Learning

This research project looks to answer the question: How does menstrual stigma in rural and urban Bangladesh affect women’s access to menstrual health care?

The research question was borne from personal experiences with menstrual stigma and seeing it firsthand in many areas of Bangladesh. These firsthand experiences come from women whom I interviewed in urban and village locations in Bangladesh in 2017. The research question looks to explore how women feel about seeking help for or talking about their menstrual issues. In asking this question, I want to explore what is at stake for women due to the powerful presence …

Selenomethionine Protects Mutant Tau N27a Cell From Oxidative Stress And Decreases Phosphorylation Of Tau, Madelin Locicero

Celebration of Learning

Alzheimer’s Disease (AD) is neurodegenerative disease characterized by loss of cells and aggregated tau in the hippocampus. Hyperphosphorylated tau causes the misfolding of tau proteins (aggregated tau), which are responsible for proper neuronal activity. Selenium-methionine has been known to decrease the amount of phosphorylated tau within mutant and wild type 3xTg- AD mice. However, selenium can be toxic to cell depending on the type of cells and the concentration of selenium. The purpose of this study is to determine the effect selenium-methionine has on decreasing hyperphosphorylation of tau, protecting cells from oxidative stress, and decreasing the amount of aggregated tau …

A Multimodal Approach To Investigate Brain Reorganization After Spinal Cord Injury Using Functional Magnetic Resonance Imaging And Functional Near-Infrared Spectroscopy, Keerthana Deepti Karunakaran

Dissertations

Traumatic Spinal Cord Injury (SCI) results in structural and functional neurological changes at both the brain and the level of the spinal cord. Anatomical studies indicate decreased grey matter volume in sensorimotor and non-sensorimotor regions of the cortex following SCI; whereas, neurophysiological findings mostly report altered functional activity in the sensorimotor nodes of the cortex, subcortex, and cerebellum. Therefore, it is currently unknown whether tissue atrophy observed in non-motor related areas has any concomitant functional consequences. Furthermore, the neural underpinnings of adaptive neuroplasticity after SCI is not well-defined in the current literature. Hence, this dissertation is a pioneer study investigating …

High-Performance Learning Systems Using Low-Precision Nanoscale Devices, Nandakumar Sasidharan Rajalekshmi

Dissertations

Brain-inspired computation promises a paradigm shift in information processing, both in terms of its parallel processing architecture and the ability to learn to tackle problems deemed unsolvable by traditional algorithmic approaches. The computational capability of the human brain is believed to stem from an interconnected network of 100 billion compute nodes (neurons) that interact with each other through approximately 10¹⁵ adjustable memory junctions (synapses). The conductance of synapses is modifiable allowing the network to learn and perform various cognitive functions. Artificial neural networks inspired by this architecture have demonstrated even super-human performance in many complex tasks.

Computational systems based …

Crispr/Cas9 In Yeast: A Multi-Week Laboratory Exercise For Undergraduate Students, Randi J. Ulbricht

Open Educational Resources

Providing undergraduate life-science students with a course-based research experience that utilizes cutting-edge technology, is tractable for students, and is manageable as an instructor is a challenge. Here, I describe a multi-week lesson plan for a laboratory-based course with the goal of editing the genome of budding yeast, Saccharomyces cerevisiae. Students apply knowledge regarding advanced topics such as: CRISPR/Cas9 gene editing, DNA repair, genetics, and cloning. The lesson requires students to master skills such as bioinformatics analysis, restriction enzyme digestion, ligation, basic microbiology skills, polymerase chain reaction, and plasmid purification. Instructors are led through the technical aspects of the protocols, …

Temporal And Functional Cortical Aspects Related To Mirror Visual Feedback During Target-Directed Movement In Healthy And Stroke Individuals, Maryam Rohafza

Dissertations

Stroke is the leading cause of disability in the United States (American Heart Association, American Stroke Association) affecting 800,000 individuals annually (i.e., one person every 45 seconds). Therapy for stroke often uses repetitive task practice, which is difficult to perform for patients due to impairment. Mirror visual feedback (MVF) based rehabilitation uses the effect of observing the mirror reflection of volitional movement of one limb, to activate visuomotor brain areas that process movement of the opposite limb. In persons with hemiplegia due to stroke, exercising the less affected limb while observing its reflection, perceived by them as the motion of …

Risk Assesment Of Air Pollution Exposure (No2, So2, Total Suspended Particulate, And Particulate Matter 10 Micron) And Smoking Habits On The Lung Function Of Bus Drivers In Palembang City, Elvi Sunarsih, Suheryanto Suheryanto, Rini Mutahar, Rahmi Garmini

Kesmas

Nitrogen dioxide (NO2), carbon monoxide (CO), sulfur dioxide (SO2), Particulate Matter (PM10) and TSP are the most common and harmful air pollutants to humans. In short period, air pollution exposure at 5 ppm for 10 minutes to humans causes dyspnea, and when the level is increase to 800 ppm could cause 100% mortality in animals. This study was an analytical research, with cross sectional design and risk analysis. One hundred subjects were analyzed in this study. The results showed that non-cancer Hazard Index (HI) for realtime exposure with mean value was NO2: 1.85; SO2: 2.92; TSP: 7.09; and PM10: 11.7 …

Identification Of Eomes-Expressing Spermatogonial Stem Cells And Their Regulation By Plzf., Manju Sharma, Anuj Srivastava, Heather Fairfield, David E. Bergstrom, William F Flynn, Robert E Braun

Faculty Research 2019

Long-term maintenance of spermatogenesis in mammals is supported by GDNF, an essential growth factor required for spermatogonial stem cell (SSC) self-renewal. Exploiting a transgenic GDNF overexpression model, which expands and normalizes the pool of undifferentiated spermatogonia between Plzf ^+/+ and Plzf ^lu/lu mice, we used RNAseq to identify a rare subpopulation of cells that express EOMES, a T-box transcription factor. Lineage tracing and busulfan challenge show that these are SSCs that contribute to steady state spermatogenesis as well as regeneration following chemical injury. EOMES+ SSCs have a lower proliferation index in wild-type than in Plzf ^lu/lu mice, suggesting that PLZF …

Does Variability Of Footfall Kinematics Correlate With Dynamic Stability Of The Centre Of Mass During Walking?, Niklas König Ignasiak

Physical Therapy Faculty Articles and Research

A stable walking pattern is presumably essential to avoid falls. Stability of walking is most accurately determined by the short-term local dynamic stability (maximum Lyapunov exponent) of the body centre of mass. In many studies related to fall risk, however, variability of step width is considered to be indicative of the stability of the centre of mass during walking. However, other footfall parameters, in particular variability of stride time, have also been associated with increased risk for falling. Therefore, the aim of this study was to investigate the association between short-term local dynamic stability of the body centre of mass …

The Consequences Of Cold Water Immersion: Impacts And Treatment, Patrick J. Buck Ph.D., Commander William Roberts, Commander Ken Minehane

International Journal of Aquatic Research and Education

This paper documents a demonstration project conducted by the authors under the auspices of the Irish Naval service. It explores and describes in detail the consequences that cold water immersion can have on the human body. Further, this study investigates post immersion treatment and survival challenges and proposes appropriate casualty care regimes with specific focus on ‘post rescue collapse’ and ‘afterdrop.’ Observations of individual differences in response are reported.

Enhancing Chronic Pain Management Motivational Interview Among Lower Back Pain Patients, Melissa L. Hines-Antico

Doctor of Nursing Practice Final Manuscripts

Purpose: Untreated chronic pain is a nationwide epidemic affect individual physically, psychologically, and financially. Low back pain is the most common subset of chronic pain. Restricted clinic time and a focus on procedural/prescriptive methods for managing pain prohibits patient education regarding self-care, and formation of a relationship with the provider.

Design: Article review yielded 20 articles that supported the use of motivational interviewing for chronic pain in lower back pain patients. They were evaluated for their strength of evidence on a scale of 1-6. One article was ranked level I as a meta-analysis, and six were ranked as level II …

After Implementation Of The Aca – Coverage Gaps Among Rural Latinos Still Remain, Arlesia L. Mathis, Matthew Dutton, Ivette A. López, Alan Becker, C Perry Brown

Florida Public Health Review

In this study, we assessed health needs and insurance coverage among a rural Latino population. A health needs survey was conducted in 2015 with approximately 100 Latino residents living in a rural Florida county. The survey included questions on socio-economic characteristics, type of insurance coverage, lapses in coverage, delays in care and satisfaction with health services. Only 15% of respondents had insurance through their employer, and 11% had Medicaid. Over 45% of participants had no health insurance, and 20% had no insurance for more than three years. One in ten had a medication delay due to lack of coverage/money, and …

Preparing Learners For Learning In The Engaged Learning Classroom, Maryam Alizadeh, Dean Parmelee, Irina Overman, Mohamad Aljasem

Medical Education Faculty Publications

This set of Tips is written to make the best use of an Engaged Learning Classroom (ELC), which some may refer to as the ‘flipped classroom.’ Strategies for the ELC include Team-Based Learning (TBL), Peer Instruction (PI), Case-Based Learning (CBL). Our focus will be on the design and implementation of the out-of-class phase for any ELC activity since this is as important as the in-class phase, but often neglected. Experience has shown that the quality of learning from the ELC is highly dependent on the preparation before, and follow-up to the class session. The instructor’s designation of material (written, audio-visual, …

Sedentariness, Productivity, Perception And Long Term Health Effects Of Sit-Stand Workstation At Work: A Literature Review, Danielle Mengistab

Theses

Sedentary behavior has been increasingly identified as a contributor to poor health outcomes and sit-stand workstations (SSW) have been introduced in offices to potentially reduce these adverse effects. This thesis presents a review of literature on SSW as they relate to musculoskeletal complaints, sedentary behavior, users’ perception after short- and long-term use, productivity and cardiometabolic markers. To be included in the review, studies were required to include the adult working population subject to a sit-stand workstation intervention with above outcome measures. The review indicates that on an average, SSW has decreased sitting time by about 85 minutes per eight hour …

Obesity As Type 2 Diabetes Common Comorbidity: Study Of Type 2 Diabetes Patients’ Eating Behaviour And Other Determinants In Jakarta, Indonesia, Isna Aulia Fajarini, Ratu Ayu Dewi Sartika

Kesmas

Obesity is one of the comorbidities widely occurred among type 2 diabetes patients. It is one of the most modifiable risk factors for the prevention of other comorbid conditions such as diabetic nephropathy and cardiovascular disease. The aim of this study was to recognize eating behaviour, physical activity, and other related factors, also their correlation with obesity as comorbidity among type 2 diabetes patients. Using cross-sectional design, data were collected from purposively selected 133 members of “PROLANIS” in Jatinegara Primary Health Care, East Jakarta. Food intake was assessed by 1x24 hours food recall and FFQ, physical activity by GPAQ. The …

Post Hypertension And Stroke: A Case Control Study, Aulia Imanda, Santi Martini, Kurnia Dwi Artanti

Kesmas

The purpose of this study was to determine the factors that influence the incidence of stroke including smoking status, past hypertension , past diabetes, diet, physical activity, alcohol consumption. The design of this study is case control with a ratio of 1: 1. The total number of respondents is 132 people. Research subjects were selected using systematic random sampling. This research was conducted at Ngudi Waluyo Hospital in Wlingi. Blitar, Indonesia in October till November 2017. Bivariate analysis showed that factors significantly related to stroke were smoking status (p=0.011, OR=2.6), history of past hypertension (p=0.00, OR= 6), past diabetes (p=0.015 …

Type 2 Diabetes Patients’ Need For Physical Activity Programming: A Qualitative Study At A Yogyakarta Hospital Clini, Novita Intan Arovah, Bernadeta Wara Kushartanti, Tracy L. Washington, Kristiann C. Heesch

Kesmas

Physical activity programs offered in Indonesian hospitals are often inadequate to help type 2 diabetes (T2D) patients meet international physical activity recommendations. This study aimed to identify T2D patients’ physical activity enablers and barriers, their preferences for, and experiences with, physical activity programming, with a view to developing future programs that are suited to these patients’ needs and preferences. Four focus groups were conducted with 28 patients (50% female) of the T2D clinic at the Local General Hospital of Yogyakarta. Discussions were thematically analysed in NVivo 10. The most reported types of physical activity were walking and participation in the …

Dengue Haemorrhagic Fever And House Conditions In Kupang City, East Nusa Tenggara Province, Wanti Wanti, Ririh Yudhastuti, Hari Basuki Notobroto, Sri Subekti, Oktofianus Sila, Ragu Harming Kristina, Feby Dwirahmadi

Kesmas

Kupang City has the highest Incidence of DHF in East Nusa Tenggara and also higher than the national figure. This study aims to analyze the relationship between housing conditions and the DHF incidence in the Kupang City. This observational study uses a case-control study in 25 villages with a total sample of 500 people. Data is analyzed using t test and chi square test. The house conditions were significantly related to the DHF incidence (p≤0.05), namely house lighting, water usage, wall construction, ventilation area and ownership of clean water facilities. People are advised to ventilate the house ≥10% of the …

Risk Factor Analysis Of Overnutrition Among Elementary School Children In Pekanbaru: An Urban-Rural Perspective, Arfianti Arfianti

Kesmas

The prevalence of childhood overnutrition is increasing in many parts of the world including Indonesia. National basic health research (RISKESDAS) 2010 showed that over-nutrition in urban children (10.4%) was greater than in rural areas (8.1%). The purpose of this study was to analyse risk factors for overnutrition on elementary students in urban and rural areas in Pekanbaru. This was an observasional analytical study with cross-sectional design. This study involved 137 urban and 113 rural students from six elementary schools in Pekanbaru recruited by quota sampling technique. This study was conducted between April-May 2018. The results showed that the proportions of …