Medicine and Health Sciences Commons^™

Relationship Between Balance And Physical Activity In Subjects With Non-Specific Chronic Low Back Pain, Muhsen B. Alsufiany

Loma Linda University Electronic Theses, Dissertations & Projects

Most research on sedentary lifestyle has focused on pain and disability outcomes, while neuromuscular outcomes (postural control and strength) have received less attention. The objective of the present study was to determine whether low level of physical activity is negatively associated with measures of lower body muscular strength and postural control in subjects with and without non-specific chronic low back pain (NSCLBP). Twenty-four subjects with NSCLBP (28.8±5.9 years) and 24 age, gender, and Body Mass Index (BMI) matched healthy controls participated in the study. Subjects were sub-classified into four subgroups based on their level of physical activity using the International …

Does Self-Evaluation And Education In Students Change Attitudes And Beliefs Towards Weight Stigma?, Henry A. Garcia

Loma Linda University Electronic Theses, Dissertations & Projects

The current state of global ensures physical therapists will encounter patients that are overweight/obese in all clinical settings, which makes them exceptionally positioned to promote lifestyle modifications to their patients. Unfortunately, weight stigma is highly prevalent among health care providers. Weight stigma has been shown to have adverse effects on patients. The purpose of this study is to measure weight bias in the doctor of physical therapy (DPT) students. Elicit change in obesity stigma in DPT students by way of self-evaluation while enrolled in a course Aspects of Health Promotion (AHP). Methods: Sixty students enrolled in AHP course participated in …

Effects Of Head Motion On Balance In Middle-Aged And Young Adults With Chronic Motion Sensitivity, Ammar E. Hafiz

Loma Linda University Electronic Theses, Dissertations & Projects

Chronic motion sensitivity (CMS) often leads to a variety of symptoms including postural instability. There is limited research describing the effects of active head motion on standing postural stability in adults with motion sensitivity. Previous research has described the negative effects of chronic motion sensitivity on postural stability during active head motion. The purpose of this study was to compare the effects of slow and fast head motions, in multiple planes, on postural stability in healthy middle-aged adults with and without CMS. Secondary objective was to compare the effects of head motion on postural stability between young and middle-aged adults, …

How Korean Couples Construct Marital Relationships: A Qualitative Study, Young Joo Kang

Loma Linda University Electronic Theses, Dissertations & Projects

With increased economic and employment opportunities for women, South Korean couples are challenged by division of labor in the family. This qualitative study examined how marital partners maintain their relationships in light of rapid social change. The study employed social constructionism and feminist theory as conceptual frameworks. Through social constructionism, I sought to understand the interactive roles marital partners perform as they attempt to balance family needs and responsibilities within the context of evolving gender ideas. Feminist theory provided an additional lens to further understand the nuances of partners’ beliefs and expectations about their own gender and that of their …

Social Empathy And Associated Factors Among Nurses: A Mixed Method Study, Gudrun Klim

Loma Linda University Electronic Theses, Dissertations & Projects

The aim of this study was to measure and describe social empathy among nurses and to explore how selected demographic, personal, and work-related factors were associated with social empathy. A cross-sectional, observational research design employing mixed methods (i.e., embedded triangulation with quantitative and qualitative components) was used. Registered Nurses employed at a large northwestern US healthcare system comprised the sample (N = 614 [17% response rate]). The sample was recruited via an email invitation that included a link to the study instruments. These instruments included demographic questions developed by the investigator and the following validated tools: Interpersonal and Social Empathy …

Efficacy Of The Dorsal Application Of Kinesio Tape For Carpal Tunnel Syndrome, Donnamarie Carter Krause

Loma Linda University Electronic Theses, Dissertations & Projects

Upper extremity musculoskeletal disorders (MSD), such as Carpal Tunnel Syndrome (CTS) affect worldwide working populations. CTS symptoms are problematic especially when signs and symptoms are not substantial enough to require surgical intervention. Conservative treatments have mixed effectiveness, and there is yet to be a best option for chronic low-grade CTS. Kinesio tape is an emerging modality, the dorsal application may provide biomechanical support while allowing functional movement. Thus, the objective of this study was to determine if the dorsal application of Kinesio tape applied to the wrist extensors for individuals with carpal tunnel syndrome makes a difference in occupational performance …

Comparison Of Surgical Outcomes Of The Posterior And Combined Approaches For Repair Of Cervical Fractures In Ankylosing Spondylitis., Panya Luksanapruksa, Paul William Millhouse, Victor Carlson, Thanase Ariyawatkul, Joshua Heller, Christopher K. Kepler

Department of Orthopaedic Surgery Faculty Papers

STUDY DESIGN: Retrospective cohort study.

PURPOSE: To evaluate surgical outcomes and complications of cervical spine fractures in ankylosing spondylitis (CAS) patients who were treated using either the posterior (P) or combined approach (C).

OVERVIEW OF LITERATURE: Ankylosing spondylitis typically causes progressive spinal stiffness that makes patients susceptible to spinal fractures. CAS is a highly unstable condition. There is contradictory evidence regarding which treatment option, the posterior or the combined approach, yields superior clinical results.

METHODS: A single institution database was reviewed for data in the period 1999 to 2015. All CAS patients who underwent posterior or combined instrumented fusion were …

Tendinosis Develops From Age- And Oxygen Tension-Dependent Modulation Of Rac1 Activity., Rowena Mcbeath, Richard W. Edwards, Brian J. O'Hara, Mitchell G. Maltenfort, Susan M. Parks, Andrzej Steplewski, A. Lee Osterman, Irving M. Shapiro

Department of Orthopaedic Surgery Faculty Papers

Age-related tendon degeneration (tendinosis) is characterized by a phenotypic change in which tenocytes display characteristics of fibrochondrocytes and mineralized fibrochondrocytes. As tendon degeneration has been noted in vivo in areas of decreased tendon vascularity, we hypothesized that hypoxia is responsible for the development of the tendinosis phenotype, and that these effects are more pronounced in aged tenocytes. Hypoxic (1% O₂ ) culture of aged, tendinotic, and young human tenocytes resulted in a mineralized fibrochondrocyte phenotype in aged tenocytes, and a fibrochondrocyte phenotype in young and tendinotic tenocytes. Investigation of the molecular mechanism responsible for this phenotype change revealed that …

Vgkc Antibody (Anti Lg1) Associated Limbic Encephalitis In A Young Adult With Full Recovery., Farheen Niazi, Madeeha Iftikhar, Rizwan Ali, Tahir Aziz

Pakistan Journal of Neurological Sciences (PJNS)

A young boy with no premorbids was admitted with fever, fits and psychosis. His initial investigations including cerebrospinal fluid (CSF) routine examination, electroencephalogram(EEG) and MRI brain with contrast were normal. His autoimmune encephalitis panel revealed positive voltage gated potassium channel(VGKC) antibodies, anti -leucine rich glioma inactivated 1 antibody (LG1) group and was give five doses of methylprednisolone and five sessions of plasmapheresis. Psychiatric symptoms took one month to respond. He had a complete recovery. Autoimmune limbic encephalitis should be diagnosed promptly in young patient with fit, psychosis and a high index of suspicion should be kept as initial work up …

Polyneuropathy Associated With Iga Paraproteinemia: A Case Report And Literature Review., Waleed Shahzad, Sumaira Nabi, Hafiza Faiza Mushtaq, Tehmina Inayat, Muhammad Hassan, Haris Majid Rajput, Zakir Jan, Mazhar Badshah

Pakistan Journal of Neurological Sciences (PJNS)

Paraproteinemia is precipitated by an accumulation of monoclonal plasma cells or B lymphocytes. Idiopathic neuropathies that are associated with paraproteinemia account for only 10% of the neuropathies. Paraprotein acts like an antibody and is targeted against myelin and axons present in the peripheral nerves. Despite being of interest for quite a long time, the caudal relationship between paraproteinemias and peripheral neuropathies still remains a sorcery. We report a case of a middle aged male who presented with pain and parasthesias in both arms and legs. His workup revealed him to be having a paraproteinemic neuropathy consistent with IgA Lambda chains …

Is It Really Transverse Myelitis? Acute Flaccid Myelitis A Rare Entity., Hina Yusuf, Arsalan Ahmad, Ejaz Ahmed Khan

Pakistan Journal of Neurological Sciences (PJNS)

Acute Flaccid Myelitis is a relatively new and rare disease entity which was recognized for the first time in United States in 20121. Usually children below 18 years of age present with sudden onset rapidly progressive flaccid paralysis sometimes following upper respiratory tract infection. To date no cases have been reported from Afghanistan and Pakistan. We are reporting case of a young girl who presented with sudden onset flaccid paralysis and respiratory distress. Her MRI Cervical spine showed longitudinally extensive transverse myelitis. One year after the onset of disease flaccid paraparesis continued despite various treatments. It is important to report …

Spectrum Of Electroencephalogram Finding In Children With Newly Diagnosed Epilepsy –An Experience At A Tertiary Care Hospital., Sanam B. Rajper, Khairunnisa Mukhtiar, Fozia Baloch, Shahnaz H. Ibrahim, Abdul Rashid Memon

Pakistan Journal of Neurological Sciences (PJNS)

Epilepsy is the most common neurological disorders that affect all age groups. It is characterized by at least two unprovoked seizures more than 24 hours apart. The most common investigation used for both diagnosis and management is an Electroencephalogram (EEG), which is relatively cheap and easy to perform. However, EEG requires technical expertise and is prone to misinterpretation. Objective: To determine the frequency of abnormal EEG findings in children with newly diagnosed epilepsy at tertiary care hospital.

Humanism And Mental Health Of Married Female Patients With Systemic Lupus Erythematosus., Hafiza Muzammal Shafiq, Dr. Muhammad Rafiq, Dr. Zahid Mahmood

Pakistan Journal of Neurological Sciences (PJNS)

Autoimmune diseases exert adverse impact on the psychological, social and physical well-being of the individuals who suffer from such diseases. Systemic lupus erythematosus is one of chronic illnesses that disturb the all areas of life especially psychosocial perspective of life. In such conditions, belief and view of patients about their own self is necessary to prognosis of their health. Studies suggest that humanism is one of those protective factors that can lead risky health towards better life.

The Mhgap; Will It Bridge The Mental Health Treatment Gap In Pakistan?, Shireen Najam, Aisha Sanober Chachar, Ayesha Mian

Pakistan Journal of Neurological Sciences (PJNS)

In Pakistan, the treatment gap for mental disorders is significantly high. Pakistan faces a unique problem of sustainable delivery. In 2009, WHO launched a mental health gap action program (mhGap) to provide evidence-based services at the primary and secondary level for the prevention and management of psychiatric and neurological disorders. This article highlights the discrepancies of the systems and issues related to mental health services provision in Pakistan. By discussing two initiatives of mhGap implementation for the Pakistani health system, authors have surveyed core areas where the sustainability of such a model can be compromised. The structural challenges marked by …

Alterations In Human Reaction Time Upon Consumption Of Taurine-Caffeine Based Energy Drink. A Gender Based Study., Asif Abbasi, Amaila Fazal, Faizan Mirza, Sadaf Ahmed

Pakistan Journal of Neurological Sciences (PJNS)

Energy drinks contains several potentially psychoactive ingredients including taurine, glucoronolactone, and caffeine that increases the human performances, reaction time and mood with relative differences to visual and auditory stimuli between both the genders.

Vagal Nerve Stimulation; Current And Future Interventions, Sidra Saleem, Muhammad Wasay

Pakistan Journal of Neurological Sciences (PJNS)

Vagus Nerve is the 10th and the largest cranial nerve of the parasympathetic system, consist of approximately 20% efferent and 80% afferent. It is a big nerve, providing autonomous, cardiovascular, respiratory, gastrointestinal, immune and endocrine systems.

Perception Of Shisha Smoking & Drug Abuse Among University Students Of Karachi, Farwah Rizvi, Lubna Naz, Nazneen Zehra

Pakistan Journal of Neurological Sciences (PJNS)

Tobacco smoking in the form of cigarettes and shisha hasbecome a sign of modernization and trend among youth for pleasant and relaxing experience. Drug addiction is the most common problem in young ones nowadays causing craving practices and long-term consequences includesdisturbances in physical and mental health.

Prevalence Of Risk Factors Promoting Diabetic Neuropathy ., Aisha Qadir, Sumera Sohail1, Lubna Naz, Ghazala Yasmeen, Nazish Iqbal

Pakistan Journal of Neurological Sciences (PJNS)

Diabetic neuropathy is the worst consequence of diabetes mellitus leading to nerve dysfunction that is the cause of several complications such as pain, loss of sensitivity, damage to body systems, foot ulcers, morbidity and amputations etc. The aim of the present work was to study the prevalence of risk factors and occurrence of diabetic neuropathy in patients with diabetes, and how much diabetic neuropathy complications affect the life of diabetic patients.

Factors Associated With Geriatric Morbidity And Impairment In A Megacity Of Pakistan, Saniya Sabzwari, Romaina Iqbal, Zafar Fatmi, Iqbal Azam Syed

Department of Family Medicine

Background: The elderly population is increasing globally. In Pakistan, the elderly comprise 6% of the population that is predicted to triple by 2050. Non-communicable diseases are common health problems of the elderly in Pakistan, however, resulting geriatric impairments and disability are unknown. This study was conducted to determine geriatric impairments and identify associated socio-demographic factors and comorbidities among community dwelling elderly in Karachi, Pakistan.
Methods: A cross-sectional study was conducted during 2013-2014. Community clusters were selected from all sub-districts of Karachi, the largest city of Pakistan. Data was collected from systematically selected households within these clusters from individuals, aged ≥60 …

Serum Level Of Matrix Metalloproteinase 3 (Stromelysin 1) In Patients With Systemic Lupus Erythematosus: Relation To Clinical Nephritis And Neuropsychiatric Manifestations, Eman R. Amer, Fatema A. Elshabacy, Hala A. Elhameed Tabl, Lobna Y. Ebrahim, Taghreed F. M. Mostafa

Journal of Medicine in Scientific Research

Aim The aim of this study was to assess serum matrix metalloproteinase 3 (MMP-3) level in patients of systemic lupus erythematosus (SLE) and its relation to various clinical and laboratory findings. Patients and methods The study involved 40 female patients with SLE as a study group and 20 sex-matched and age-matched healthy individuals as a control group. All patients were subjected to thorough clinical examinations and laboratory investigations. Disease activity was assessed using SLE Disease Activity Index, as well as Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index. Serum level of MMP-3 was assessed using enzyme-linked immunosorbent assay …

Endovascular Management Of Medically Refractory Intracranial Arterial Stenosis, Ahmed El-Bassiouny, Ayman Nassef, Eman Awad, Hossam Eldin Afify, Mohamed A. Shafik, Romany A. Yousef

Journal of Medicine in Scientific Research

Background Despite aggressive medical therapy, the risk of recurrent stroke in patients with symptomatic intracranial arterial (ICA) disease is as high as 15% per year. In patients with severe stenosis (>70%) and in certain high-risk groups, the risk of recurrent stroke has been reported to be as high as 25% per year. Objective Our study aimed to follow-up the patients after ICA stenting by using transcranial duplex (TCD). Patients and methods This is a retrospective single-center study carried out on data of patients recruited to Neurovascular Unit of El Mataria Teaching Hospital during the period from June 2015 to …

Once-Daily Versus Twice-Daily Enoxaparin For The Initial Treatment Of Acute Deep Venous Thrombosis: A Case–Control Study, Ahmed Samir, Asim M. Herz-Allah, Mohamad T. Yusuf, Mohamed M. Gouda, Mourad I. Alkhouly

Journal of Medicine in Scientific Research

Background In the initial treatment of deep venous thrombosis (DVT), enoxaparin is administered twice daily. A once-daily treatment regimen is more convenient for the patients and may optimize home treatment. However, it is not clear whether a once-daily treatment regimen is as safe and effective as a twice-daily treatment regimen. Purpose Our objective is to assess and compare the efficacy (in terms of recurrent venous thromboembolism) and safety (i.e. major hemorrhagic events) of once-daily versus twice-daily administration of enoxaparin for the initial treatment of DVT. Patients and methods A case–control study was conducted. We studied the efficacy and safety of …

Efficacy Of Alternative Seating On Attention, In-Seat Behavior, And Occupational Performance In Children With Attention Deficit Hyperactivity Disorder, A. Chacko, K. Kosztyo, N. Long, Z. Mullan, J. Norkitis, L. Wratcher, M.-C. Potvin, Phd, Otr/L

Student Papers, Posters & Projects

Currently, there is one systematic review conducted by Gochenour and Poskey7 that synthesize current research evidence regarding alternative seating for students with attention difficulties. A limitation of this review, as noted by the authors, is a lack of a consistent definition of attention difficulty in the studies they included. A systematic review focused on a specific, well-defined diagnosis will better contribute to practice recommendations since these recommendations will be tailored to a clear and comprehensive understanding of the child’s attentional and occupational challenges. The review also included studies of children with autism spectrum disorder (ASD).7 While those with ASD may …

Assessment Of Sensitivity And Specificity Of Ultrasonographic Features Of Gout In Intercritical And Chronic Phases, Abeer H. Ismaiel, Mohamed A. Safy, Nisreen H. Mohmoud, Tamer A. Aboul-Sood El-Kassas

Journal of Medicine in Scientific Research

Aim To study the usefulness of ultrasonography (US) in the diagnosis of gouty arthritis and to assess its sensitivity and specificity in intercritical and chronic stages and also its use in comparing patients with high serum uric acid (HSUA) and low serum uric acid (LSUA). Patients and methods We studied 60 patients known to be gouty in either chronic phase or intercritical phase, diagnosed clinically and through laboratory assessments, and 30 controls. Demographic, clinical, and serological data were evaluated. Knee and first metatarsophalangeal joints were assessed by musculoskeletal US by a blinded radiologist. Results A total of 53 (88.3%) patients …

Prevalence Of Anemia In Patients With Type 2 Diabetes, El-Saied Shaheen

Journal of Medicine in Scientific Research

Background Diabetes mellitus (DM) has a high prevalence worldwide. It leads to various complications, including microvascular and macrovascular complications. The nephropathy may undermine the renal production of erythropoietin, positively contributing to an increased anemia framework. The inflammatory situation created by kidney disease also interferes with intestinal iron absorption. Therefore, diabetic patients with kidney disease have higher risk for developing anemia. Aim The aim of this work was to determine the prevalence and various types of anemia in patients with type 2 DM. Patients and methods After obtaining informed written consent, all diabetics as well as control individuals were subjected to …

Effect Of Sildenafil On Stable Chronic Heart Failure: A Prospective Randomized-Controlled Clinical Trial, Hatem Khairy, Wael Abdelatief Elhakeem

Journal of Medicine in Scientific Research

Background Patients with systolic heart failure (HF) who develop secondary pulmonary hypertension have reduced exercise capacity and increased mortality compared with HF patients without pulmonary hypertension. A defective nitric oxide signaling is involved in left ventricular (LV) diastolic abnormalities and remodeling. Phosphodiesterase type 5 inhibition, by blocking degradation of nitric oxide second-messenger cyclic guanosine monophosphate, might be beneficial. Aim of the study In our study, we tested the effects of phosphodiesterase type 5 inhibition (sildenafil) on LV ejection fraction, diastolic function, pulmonary artery pressure, and clinical status. Patients, methods, and results One hundred HF patients (New York Heart Association classes …

Efficacy Of On-Pump Versus Off-Pump Coronary Artery Bypass Grafting In Early-Stage Renal Impairment Without Dialysis Therapy, Ashraf Zahra

Journal of Medicine in Scientific Research

Background Coronary artery disease is the most common of the cardiovascular diseases that can be treated with coronary artery bypass grafting (CABG) surgery, with either on-pump or off-pump technique. In this study, we aimed to compare the early results of isolated CABG, using on-pump and off-pump techniques, in patients with preoperative mild-to-moderate elevation of serum creatinine (1.6–2.5 mg/dl) level who did not require maintenance dialysis to support renal function. Patients and methods This prospective nonrandomized study included 60 patients who complained of symptoms of coronary artery disease and subsequently underwent myocardial revascularization at Cardiothoracic Surgery Department, Shebin El-Kom Teaching Hospital, …

A Comparative Study Between Custodiol And Warm Blood Cardioplegia In Coronary Artery Bypass Graft Operation With Poor Left Ventricular Function, Ahmed S. Ali, Hassan Mohamed Moftahb, Mohamed Ali El Ghanamb, Moustafa Gamal Eldin Moustafab, Samir Ahmed Ataa

Journal of Medicine in Scientific Research

Background Cardioplegia is responsible for myocardial protection during open heart surgery. Cardioplegia was first presented as an agent for hypothermic hyperkalemic arrest. Blood was then introduced as a vehicle to convey potassium to the heart. Custodiol Histidine-Tryptophan- ketoglutarate (HTK) solution is safe and used as a single dose, which can last for up to 3 h. The comparison of the clinical outcomes of this particular solution with warm blood cardioplegia in coronary artery bypass graft (CABG) with poor left ventricular (LV) function has received little attention. Objective To compare the clinical outcomes of custodiol solution with warm blood cardioplegia in …

Comparing Two Formulas To Estimate The Correct Depth Of The Neonatal Umbilical Venous Catheter Insertion, Hany W. G. Michael

Journal of Medicine in Scientific Research

Aim The rate of complications among neonates with incorrectly positioned umbilical venous catheters (UVCs) is considerably increased. This prospective study aimed to evaluate whether the use of birth weight (BW) or body surface measurements as a guide for proper depth estimation of the UVC insertion was more accurate. Patients and methods A total of 104 neonates were assigned to two groups according to procedure used for proper UVC depth insertion: shoulder–umbilicus length graphs versus BW-based formula. Radiological assessment of correct catheter tip position was determined in both groups. Results The overall success rate for UVC insertion was 96% (100/104). However, …

Determination Of Gestational Age By Ultrasonographic Measurement Of Fetal Kidney Length During Third Trimester Of Pregnancy, Ibrahim Elmorsy Shalaby, Mahmoud Elsayed Abdelrazek Abo-Donia

Journal of Medicine in Scientific Research

Objective The aim of accurate estimation of gestational age is reduction of fetal and maternal morbidity and mortality as much as possible. The routine fetal biometry ultrasound (US) measurement at third trimester is not adequate all times; for this purpose, new parameters must be developed. Average fetal kidney length (FKL) is one of them and may add value as a single parameter. Design A prospective study to assess the gestational age at the third trimester using FKL US measurement was done. Patients and methods Seventy-five noncomplicated pregnant women at third trimester (25 as a training sample and 50 as a …