Medicine and Health Sciences Commons^™

Ossification Of The Cruciform Ligament Of Atlas; A Rare Cause Of Cervical Myelopathy: Case Report And Review Of Literature, Muhammad Waqas Saeed Baqai, Gohar Javed, Mirza Zain Baig

Section of Neurosurgery

We present a case of cervical myelopathy secondary to ossification of the cruciform ligament (also known as cruciate ligament). This is a rare phenomenon that, to the best of our knowledge, has only been reported 16 times previously in literature. We have added a review of literature after our case presentation. We hope that by doing so, we may aid clinicians reach early diagnosis so as to be able to better manage this rare disease.

Perianal Necrotizing Fasciitis With Retroperitoneal Extension: A Case Report From Pakistan, Mirza Zain Baig, Abeer Aziz, Umme E Hani Abdullah, Muhammad Salman Khalil, Sumiya Abbasi

Section of Neurosurgery

Necrotizing fasciitis is a rare but potentially fatal condition. It is defined as a rapidly spreading infection of the subcutaneous soft tissue. Extension into the retroperitoneum may further complicate this deadly condition. We report a case of a 45-year-old gentleman who presented to our institute with perianal necrotizing fasciitis with extension into the retroperitoneum. He was managed with antibiotics and prompt surgical debridement. Our patient had a positive outcome which may be due to the fact that we had a high clinical suspicion, on the basis of which we opted for early operative management rather than delaying definitive treatment by …

Concept Mapping: A Way Of Meaningful Learning For Medical Students, Rehana Rehman, Salman Siddiqi, Mukhtiar Baig

Department of Biological & Biomedical Sciences

Abstract are not provided by the author/publisher

Can Low Vitamin D Binding Protein Levels Be A Cause Of Infertility In Females?, Bisma Badr, Sadia Cassim, Rehana Rehman

Department of Biological & Biomedical Sciences

Abstract are not provided by the author/publisher

Clinical Emergency Care Research In Low-Income And Middle-Income Countries: Opportunities And Challenges, Adam R. Aluisio, Shahan Waheed, Peter Cameron, Jermey Hess, Shevin Jacob, Niranjan Kissoon, Adam C. Levine, Asad Mian, Shammi Ramlakhan, Hendry R. Sawe, Junaid Razzak

Department of Emergency Medicine

Disease processes that frequently require emergency care constitute approximately 50% of the total disease burden in low-income and middle-income countries (LMICs). Many LMICs continue to deal with emergencies caused by communicable disease states such as pneumonia, diarrhoea, malaria and meningitis, while also experiencing a marked increase in non-communicable diseases, such as cardiovascular diseases, diabetes mellitus and trauma. For many of these states, emergency care interventions have been developed through research in high-income countries (HICs) and advances in care have been achieved. However, in LMICs, clinical research, especially interventional trials, in emergency care are rare. Furthermore, there exists minimal research on …

Consumer Prices For Surgical Management Of Ankle Arthritis: Limited Availability And Wide Variability., Niall A Smyth, Brody J Dawkins, Joshua P Goldstein, Jonathan R Kaplan, Lew C Schon, Amiethab A Aiyer

Articles, Abstracts, and Reports

Background: Healthcare costs for the surgical management of ankle arthritis continue to rise. Patients are generally unaware of the prices of the services they use. Understanding the costs associated with surgical management of ankle arthritis is an important facet of patient care. The purposes of this study were to (1) determine the access to the surgical cost of total ankle arthroplasty (TAAs) and ankle arthrodesis and (2) the variability of the price between the two procedures.

Methods: Fifty foot and ankle centers (25 academic, 25 private) that perform TAAs and ankle arthrodeses were contacted using a standardized patient script. The …

Invasive Cryptococcal Meningitis Presenting As A Skull Base Mass In An Immunocompetent Host: A Case Report., Joshua Prickett, Juan J Altafulla, Anna Knisely, Zachary Litvack

Articles, Abstracts, and Reports

No abstract provided.

Global Spinal Deformity From The Upper Cervical Perspective. What Is "Abnormal" In The Upper Cervical Spine?, Peter G Passias, Haddy Alas, Renaud Lafage, Bassel G Diebo, Irene Chern, Christopher P Ames, Paul Park, Khoi D Than, Alan H Daniels, D Kojo Hamilton, Douglas C Burton, Robert A Hart, Shay Bess, Breton G Line, Eric O Klineberg, Christopher I Shaffrey, Justin S Smith, Frank J Schwab, Virginie Lafage

Articles, Abstracts, and Reports

Hypothesis: Reciprocal changes in the upper cervical spine correlate with adult TL deformity modifiers.

Design: This was a retrospective review.

Introduction: The upper cervical spine has remarkable adaptability to wide ranges of thoracolumbar (TL) deformity.

Methods: Patients >18 years with adult spinal deformity (ASD) and complete radiographic data at baseline (BL) and 1 year were identified. Patients were grouped into component types of the Roussouly classification system (Type 1: Pelvic incidence [PI]

Results: A total of 343 ASD patients were analyzed. When grouped by BL Schwab and Roussouly, Group

Conclusions: Our study suggests that upper cervical alignment remains relatively stable …

Comparison Of Asymmetric Reaming Versus A Posteriorly Augmented Component For Posterior Glenoid Wear And Retroversion: A Radiographic Study., Jia-Wei Kevin Ko, Usman Ali Syed, Jonathan D Barlow, Scott Paxton, Bryan J Loeffler, Ocean Thakar, Grant Jamgochian, Joseph A Abboud, Charles L Getz, Gerald R Williams

Articles, Abstracts, and Reports

Background: Managing posterior glenoid wear and retroversion remains a challenge in shoulder arthroplasty. Correcting glenoid version through asymmetric reaming (AR) with placement of a standard glenoid component and the use of posteriorly augmented glenoid (PAG) components are two methods used to address this problem. Our objective is to report the radiographic outcomes of patients with posterior glenoid wear and/or retroversion treated with either approach.

Methods: Patients with posterior glenoid wear and a minimum of 15 degrees of retroversion, treated with AR and standard glenoid component or with a PAG component (3 mm, 5 mm, or 7 mm posterior augmentation), were …

Alumni Journal - Volume 90, Number 2, Loma Linda University School Of Medicine

Alumni Journal, School of Medicine

Description

Graduation 2019
13 | Graduation Feature

Features
28 | Disclosure of Medical Errors: In Favor of Full Disclosure
31 | Strangers: A poem by Eunice M. Marpaung '19
32 | Department Reports: Plastic Surgery and Preventive Medicine
36 | Graduation Locations
38 | Alumni Spotlight
39 | Historical Snapshot

Editorials
2 | Guest Editorial
4 | From the President
6 | From the Dean

News
7 | The Student Fund
8 | School of Medicine News
10 | Alumni News
11 | Wedding Announcements
12 | AIMS Report

In Memoriam
41 | Featured Obituary: Leonard L. Bailey '69
43 …

Social Media Text Mining Framework For Drug Abuse: An Opioid Crisis Case Analysis, Tareq Nasralah

Masters Theses & Doctoral Dissertations

Social media is considered as a promising and viable source of data for gaining insights into various disease conditions, patients’ attitudes and behaviors, and medications. The daily use of social media provides new opportunities for analyzing several aspects of communication. Social media as a big data source can be used to recognize communication and behavioral themes of problematic use of prescription drugs. Mining and analyzing such media have challenges and limitations with respect to topic deduction and data quality. There is a need for a structured approach to efficiently and effectively analyze social media content related to drug abuse in …

What Parents Value Matters: Examining The Association Between Cultural Values, Parenting Styles/Practices, And Child Outcomes, Chen-Yun Wang

Theses and Dissertations

Researchers have identified significant relationships between parenting styles and child outcomes. However, these associations might vary in different cultures because parenting behaviors could link to cultural values. Additionally, understanding the cultural values of parents would help researchers better understand the reasons of parents’ behaviors. Therefore, the purpose of this study was to examine the relationships between parental Asian values, parenting styles, parenting practices, and child outcomes. Parents of preschool-age children (N = 273) from Taiwan completed a series of parenting values and parenting behaviors questionnaires. Teachers rated child prosocial behaviors, modesty, sociability, and impulse control. Results revealed that some domains …

The Current State Of Molecular Testing In The Treatment Of Patients With Solid Tumors, 2019., Wafik S El-Deiry, Richard M Goldberg, Heinz-Josef Lenz, Anthony F Shields, Geoffrey T Gibney, Antoinette R Tan, Jubilee Brown, Burton Eisenberg, Elisabeth I Heath, Surasak Phuphanich, Edward Kim, Andrew J Brenner, John L Marshall

Articles, Abstracts, and Reports

The world of molecular profiling has undergone revolutionary changes over the last few years as knowledge, technology, and even standard clinical practice have evolved. Broad molecular profiling is now nearly essential for all patients with metastatic solid tumors. New agents have been approved based on molecular testing instead of tumor site of origin. Molecular profiling methodologies have likewise changed such that tests that were performed on patients a few years ago are no longer complete and possibly inaccurate today. As with all rapid change, medical providers can quickly fall behind or struggle to find up-to-date sources to ensure he or …

The Impact Of Osteotomy Grade And Location On Regional And Global Alignment Following Cervical Deformity Surgery., Peter G Passias, Samantha R Horn, Tina Raman, Avery E Brown, Virginie Lafage, Renaud Lafage, Justin S Smith, Cole A Bortz, Frank A Segreto, Katherine E Pierce, Haddy Alas, Breton G Line, Bassel G Diebo, Alan H Daniels, Han Jo Kim, Alex Soroceanu, Gregory M Mundis, Themistocles S Protopsaltis, Eric O Klineberg, Douglas C Burton, Robert A Hart, Frank J Schwab, Shay Bess, Christopher I Shaffrey, Christopher P Ames

Articles, Abstracts, and Reports

Introduction: Correction of cervical deformity (CD) often involves different types of osteotomies to address sagittal malalignment. This study assessed the relationship between osteotomy grade and vertebral level on alignment and clinical outcomes.

Methods: Retrospective review of a multi-center prospectively collected CD database. CD was defined as at least one of the following: C2-C7 Cobb >10°, cervical lordosis (CL) >10°, C2-C7 sagittal vertical axis (cSVA) >4 cm, and chin-brow vertical angle > 25°. Patients were evaluated for level and type of cervical osteotomy.

Results: 86 CD patients were included (61.4 ± 10.6 years, 66.3% female, body mass index 29.1 kg/m

Conclusions: CD …

Diagnosis Of Non-Small Cell Lung Cancer For Early Stage Asymptomatic Patients., Cherylle Goebel, Christopher L Louden, Robert Mckenna, Osita Onugha, Andrew Wachtel, Thomas Long

Articles, Abstracts, and Reports

BACKGROUND/AIM: In 2016 in the United States, 7 of 10 patients were estimated to die following lung cancer diagnosis. This is due to a lack of a reliable screening method that detects early-stage lung cancer. Our aim is to accurately detect early stage lung cancer using algorithms and protein biomarkers.

PATIENTS AND METHODS: A total of 1,479 human plasma samples were processed using a multiplex immunoassay platform. 82 biomarkers and 6 algorithms were explored. There were 351 NSCLC samples (90.3% Stage I, 2.3% Stage II, and 7.4% Stage III/IV).

RESULTS: We identified 33 protein biomarkers and developed a classifier using …

School Of Nursing Newsletter Summer 2019, Southern Adventist University School Of Nursing

Southern Nursing - School of Nursing Newsletter

The Summer 2019 issue of the newsletter features information on accreditation renewal, appointment of Dr. Holly Gadd as dean, nursing honor class awards, spring break mission trips, faculty updates, and Campus Research Day.

Research News. Grants, 2019. Volume 2, University Of Mississippi. School Of Pharmacy, Soumyajit Majumdar

Grants (2015-)

Grants and contracts awarded during April-June 2019

Considering Augmentative And Alternative Communication Research For Brain-Computer Interface Practice, Kevin M. Pitt, Jonathan S. Brumberg, Adrienne R. Pitt

Department of Special Education and Communication Disorders: Faculty Publications

Purpose: Brain-computer interfaces (BCIs) aim to provide access to augmentative and alternative communication (AAC) devices via brain activity alone. However, while BCI technology is expanding in the laboratory setting, there is minimal incorporation into clinical practice. Building upon established AAC research and clinical best practices may aid the clinical translation of BCI practice, allowing advancements in both fields to be fully leveraged.

Method: A multidisciplinary team developed considerations for how BCI products, practice, and policy may build upon existing AAC research, based upon published reports of existing AAC and BCI procedures.

Outcomes/Benefits: Within each consideration, a review of BCI research …

Key Mechanisms By Which Post-Icu Activities Can Improve In-Icu Care: Results Of The International Thrive Collaboratives, Kimberley J. Haines, Carla M. Sevin, Elizabeth Hibbert, Leanne M. Boehm, Krishna Aparanji, Rita N. Bakhru, Anthony J. Bastin, Sarah J. Beesley, Brad W. Butcher, Kelly Drumright, Tammy L. Eaton, Thomas Farley, Penelope Firshman, Andrew Fritschle, Clare Holdsworth, Aluko A. Hope, Annie Johnson, Michael T. Kenes, Babar A. Khan, Janet A. Kloos, Erin K. Kross, Belinda J. Macleod-Smith, Pamela Mactavish, Joel Meyer, Ashley Montgomery-Yates, Tara Quasim, Howard L. Saft, Andrew Slack, Joanna Stollings, Gerald Weinhouse

Internal Medicine Faculty Publications

Objective: To identify the key mechanisms that clinicians perceive improve care in the intensive care unit (ICU), as a result of their involvement in post-ICU programs.

Methods: Qualitative inquiry via focus groups and interviews with members of the Society of Critical Care Medicine’s THRIVE collaborative sites (follow-up clinics and peer support). Framework analysis was used to synthesize and interpret the data.

Results: Five key mechanisms were identified as drivers of improvement back into the ICU: (1) identifying otherwise unseen targets for ICU quality improvement or education programs—new ideas for quality improvement were generated and greater attention paid to detail in …

Relative Age Effects In Elite Olympic Weightlifters, Jonathan M. Kollars, Kyle S. Beyer, Christopher B. Taber

Exercise Science Faculty Publications

PURPOSE: To determine if RAEs exist in elite Olympic weightlifters from the past five Olympic Games. METHODS: Using retrospective competition data from the International Weightlifting Federation database a total of 953 Olympic Weightlifters (595 males and 358 females) who competed in the Olympic Games between 2000 and 2016 were included in this study. Weightlifters who competed in multiple Olympic Games were only counted once and duplicates were removed from this investigation. The weightlifters were divided into subset weight classes; men lightweight (56kg, 62kg, and 69kg), men middleweight (77kg, 85kg, and 94kg), men heavyweight (105kg and 105kg+), women lightweight (48kg, 53kg, …

Female High School Athlete's Confidence About Their Future In College Athletics, Adam Potter

Master's Theses & Capstone Projects

Female athletes may begin at an early age in a sport and find success, but in many cases, there is a disconnect somewhere before entering college where females feel less confident and discontinue their athletic career before college. Some studies have looked at female athletes and their confidence level, however, there is more research that needs to be done to determine if females feel confident that they have the same opportunities available in college as their male counterparts. This study was designed to explore female athletes’ confidence level for their future in college sports. Data was gathered from female athletes …

Hepatitis B, Kayla Rodgers

Nursing Student Class Projects (Formerly MSN)

This poster presents a patient case and information about the believed disease process, hepatitis B (HBV). The poster gives information on the signs and symptoms of HBV such as fatigue, jaundice, and abdominal pain. The poster also discusses the pathophysiology of HBV. The virus attacks the healthy cells of the liver, replacing healthy cells with those infected cells to reproduce, and form more infected cells. This is significant because knowing how the virus works helps to know how to treat the virus and keep it from causing permanent damage. This poster also discusses the nursing implications that come from the …

Depression In Patients With Type 2 Diabetes Attending At Chao Phya Abhaibhubejhr Hospital, Amporn Nueangjaknak, Siriluck Suppapitiporn

Chulalongkorn Medical Journal

Background: Diabetes mellitus (DM) is one of the most common public health problems worldwide. It is achronic, debilitating disease that needs lifelong care for both physical and psychological aspects. Previousstudies on depression in diabetic patients are scant in Thailand.Objective: To determine the prevalence of depression and its associated factors in patients with type 2 diabetes at Chao Phya Abhaibhubejhr Hospital, Prachinburi Province.Methods: A cross-sectional descriptive study was conducted among patients with type 2 diabetes at the Outpatient Clinic of Chao Phya Abhaibhubejhr Hospital, Prachinburi Province, Thailand from August to December 2017. The instruments were demographic and clinical characteristics questionnaires, the …

Development Of A Prolyl Endopeptidase Expression System In Lactobacillus Reuteri To Reduce The Clinical Manifestation Of Celiac Disease, Kara Lynn Jew

Master's Theses

Celiac Disease (CD) is an autoimmune disorder that emerges due to the ingestion of gluten, a protein found in a variety of common grains such as wheat, rye, and barley. Approximately 1 in 100 individuals in the US suffer from CD, making it the most commonly diagnosed gastrointestinal disorder (Ciclitira et. al., 2005). These proline-rich gluten peptides are resistant to proteolysis and accumulate in the duodenum of the small intestine. Once in the duodenum, these peptides illicit an autoimmune response resulting in villous atrophy. Current treatment for CD requires a rigorous adherence to a gluten-free diet. Nevertheless, gluten-containing grains are …

Perspectives, Summer/Fall 2019, Volume 7, Number 2, Nova Southeastern University

Perspectives

No abstract provided.

Genetically Distinct Behavioral Modules Underlie Natural Variation In Thermal Performance Curves, Gregory W. Stegeman, Scott E. Baird, William S. Ryu, Asher D. Cutter

Biological Sciences Faculty Publications

Thermal reaction norms pervade organismal traits as stereotyped responses to temperature, a fundamental environmental input into sensory and physiological systems. Locomotory behavior represents an especially plastic read-out of animal response, with its dynamic dependence on environmental stimuli presenting a challenge for analysis and for understanding the genomic architecture of heritable variation. Here we characterize behavioral reaction norms as thermal performance curves for the nematode Caenorhabditis briggsae, using a collection of 23 wild isolate genotypes and 153 recombinant inbred lines to quantify the extent of genetic and plastic variation in locomotory behavior to temperature changes. By reducing the dimensionality of the …

Comparison Of Lower Extremity Range Of Motion During Walking Between Children With Cerebral Palsy And Normal Children, Parinnapak Mahasup, Siriluck Kanchanomai

Chulalongkorn Medical Journal

Background: Walking is very important for children with cerebral palsy but they lack voluntary coordination ofmuscle movements. Moreover, affected children have their own pattern of walking which is different from normal walking. Thus, gait analysis is a great tool for diagnosis with the aim to rehabilitate the children as best as possible.Objective: To compare lower extremity range of motion during walking between children with cerebral palsy and normal children.Methods: The participants were 15 children with cerebral palsy (5 - 15 years of age). Their motor abilities wereclassified at level 1 - 3 on the Gross Motor Function Classification System. The …

Effects Of General Obesity On Heart Rate Variability In Thai People With Physical Inactivity, Jantakan Saechee, Kanita Wannasamai, Pattharaporn Jaimanee, Decha Pinkeaw, Kroekkiat Chinda, Tharnwimol Inthachai

Chulalongkorn Medical Journal

Background: Obesity is an important risk factor of cardiovascular diseases. Heart rate variability (HRV), andmaximum oxygen consumption (VO2max) are parameters of cardiorespiratory function for determining aerobic capacity. However, the studies that investigated the effects of obesity on HRV, pulmonary function and VO2 max in male participants aged 40 and 50 years, have been limited.Objectives: This study aimed to compare HRV, pulmonary function and VO2max in male participants with normal body mass index (BMI) (18.5 – 22.9 kg/m2, n = 10), and Class I obesity (25 - 29.9 kg/m2, n = 10) and also to use HRV to assess cardiopulmonary function …

Labrad : Vol 45, Issue 2 - July 2019, Aga Khan University Hospital, Karachi

LABRAD - Departments of Pathology & Laboratory Medicine and Radiology Archives

• Novel Molecular Technique for Identifying Respiratory Tract Pathogens
• Role of Serum Galactomannan (GM) Assay in Diagnosing Invasive Aspergillosis (IA)
• Factor VIII Inhibitor – A Diagnostic Approach
• PET/CT Hybrid Imaging Technology at Aga Khan University Hospital
• Diagnostic Tests for Von Willebrand Disease
• Iron Deficiency Anemia
• Sweat Testing for Diagnosis of Cystic Fibrosis
• Flow Cytometric Identification of Abnormal B-Cells
• Direct Immunofluorescence in Bullous Skin Disorders
• Radiology-Pathology Correlation; Orthopedic Pathology
• Fecal Elastase: A Marker For Exocrine Pancreatic Function
• Edward Syndrome: Rare Autosomal Aneuploidy
• Sirolimus in Renal Transplant
• Latest Trends in Clinical Laboratory Science Technology
• Radiology-Neuropathology Correlation
• Nuchal Translucency Scan
• Bio-risk Management System in …

Cime Newsletter : June - July 2019, Cime

Centre for Innovation in Medical Education (CIME) Archives

-Enhancing team leadership skills through simulation
-CIME’s first breech delivery workshop
-Surgical simulation workshop
-SONOGAMES
-Managing postpartum haemorrhage (PPH)
-Jugaad enabling a central line simulation
-Relieving urinary obstruction
-Got a housekeeping issue?