Medicine and Health Sciences Commons^™

The Expression Of Serum Lactate Dehydrogenase In Canine Oral Tumors, Nan Choisunirachon, Urapa Klansnoh, Panrawee Phoomvuthisarn, Sirinun Pisamai, Chutimon Thanaboonnipat, Anudep Rungsipipat

The Thai Journal of Veterinary Medicine

Lactate dehydrogenase (LDH) has been reported to be a prognostic indicator of human malignant melanoma (MM), lymphoma, renal cell carcinoma and prostate cancer. In veterinary medicine, elevation of serum LDH has been reported in canine lymphoma and mammary gland tumors. However, the expression of the LDH in oral tumor-bearing dogs has not been elucidated. In this study, serum LDH levels were evaluated and compared between healthy dogs (control; n = 20) and oral tumor-bearing dogs (n = 34). Half of the tumor-bearing dogs (17dogs) had oral MM, followed by 6 dogs with oral squamous cell carcinoma (SCC), 4 dogs with …

Detection Of Rabies Virus Specific Antibody In Stray Dogs In Palestine, Adnan Fayyad, Nasr Jalboush, Ibrahim Alzuheir, Belal Abu Helal, Mohammad Manasrah

The Thai Journal of Veterinary Medicine

Stray dogs are considered as a major public health risk in rabies-endemic countries such as Palestine. The objective of the present study was to assess the presence of antibody against rabies in stray dogs in order to estimate the immune status of stray dogs for the purpose of risk management. The present study reports the first investigation for the detection of specific antibodies to rabies virus (RABV) in the serum of stray dogs in Palestine. The serum samples were collected randomly from 92 stray dogs from different seven Palestinian districts and were tested for the presence of antirabies antibodies by …

Development Of Business Models For Indigenous Genetic Improvement In Small Ruminant Farms Through Reproductive Biotechnology, Sarawanee Khunmanee, Theerawat Swangchan-Uthai, Junpen Suwimonteerabutr, Pintira Thiangthientham, Sanya Supappornchai, Mongkol Techakumphu

The Thai Journal of Veterinary Medicine

This study aimed to establish a business model of reproductive biotechnology in small ruminant. Sets of questionnaires were administered to interview 115 farmers from different regions in Thailand. Data including age, educational background, farm size and type, source of replacement breeders, breeding technology, farm problems and attitude toward the technology were collected. Logistic regression analysis along with neutral network analysis was used to identify factors associated technology interest with P< 0.05. Results showed that among 115 participants, 72.2% were interested in reproductive biotechnology. In univariate logistic regression analysis, farmer’s age [OR=0.96, 95% CI (0.93,1.00)], educational background [OR=1.17, 95% CI (0.13,0.80)], production problems [OR=1.28, 95% CI (1.12,1.478)] and marketing problems [OR=1.40, 95% CI (1.18,1.67)] were independently associated with technology interest (P< 0.05). Similar to the neural network analysis, farmer’s age, overall farm problems, marketing problems, production problems and educational background were the primary factors influencing technology interest of farmers. Next, the data from 18 semi-structured interviews were interpreted to establish suggested business models of reproductive biotechnology package. This indicated that a single business model could not fit the expectation of all farmers. Thus, six business models were established and 2 models were initially implemented in 7 farms with a moderate successful rate. In conclusion, the implement ofreproductive biotechnology in small ruminant farm should be addressed to the young farmers with high education to improve the animal genetic value and sustain their livelihoods. However, the different farm managements play a key role in the success of these business models.

Validation Of Commercially Available Eia Kit For Measurement Of Feline Plasma Kisspeptin, Prattana Tanyapanyachon, Junpen Suwimonteerabutr, Olga Amelkina, Kaywalee Chatdarong

The Thai Journal of Veterinary Medicine

Circulating kisspeptin is described to be related with the reproductive system. Astudy of plasma kisspeptin levels, thus, willprovide the better understanding of reproductive endocrinology in the domestic cat. The present study aimed (i) to validate the only available commercial kisspeptin EIA kit which is currently used in humansto be used in domestic catsand (ii) to determine and compare the plasma kisspeptin levels at different reproductive stages. The intra-assay coefficient of variation (CV) was 11.13%. The inter-assay CV ranged from 5.00 –8.25%. The parallel graphs represented the homology between human kisspeptin and feline endogenous kisspeptin. The recovery rate ranged from 78% …

Screening Antimicrobial Properties Against Mastitis Pathogens Of Turmeric Extract After Combination With Various Antiseptics, Wasana Chaisri, Noppason Pangprasit, Anyaphat Srithanasuwan, Montira Intanon, Witaya Suriyasathaporn

The Thai Journal of Veterinary Medicine

The aim of this study was to determine the screening for antimicrobial properties against mastitis pathogens of turmeric extract in combination with various antiseptics. The antibacterial effects of turmeric extract in combination with various antiseptics (5% povidone iodine, 0.5% v/v hydrogen peroxide (H2O2), 0.5% v/v chlorine (Cl2), and 0.5% v/v chlorhexidine) were determined using the agar welldiffusion method. Results showed that additional turmeric extract had significantly decreased the antimicrobial activities of either Cl2or chlorhexidine against almost all mastitis pathogens, except S. agalactiaefor Cl2 and gram negative bacteria for chlorhexidine. In contrast, no negative effect was found between turmeric extract and …

Gene Expression Profiling Of Ngf, Bdnf, Nt-3 And Trkb Receptor In The Development Of Prehierarchical Follicles Of Zi Geese (Anser Cygnoides), Cornelius Tlotliso Sello, Chang Liu, Yujian Sui, Hui Yang, Ziqiu Wang, Hongtao Lu, Jingtao Hu, Yongfeng Sun

The Thai Journal of Veterinary Medicine

The expression patterns of neurotrophins(NTs) at the gene and protein level including nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3),and TrkB receptor were investigated in the prehierarchical follicles of Zi Geese by RT-qPCR and Western blotting analysis. The mRNA levels of NGF, BDNF, NT-3and TrkBreceptor increased significantly in the small white follicles (SWF), and more interesting by BDNFand NT-3transcripts were not detectable in small yellow follicles (SYF) marked as the last stage of prehierarchical ovarian development before transition into preovulatory follicles. Western blot revealed the presence of all the target neurotrophins and high-affinity receptor at the protein level …

Comparison Of Different Methods For Sperm Vitality Assessment In Frozen-Thawed Holstein Bull Semen, Kakanang Buranaamnuay

The Thai Journal of Veterinary Medicine

The present study evaluated the accuracy of four methods, i.e. eosin-nigrosin, trypan blue, hypo-osmotic swelling test (HOST) and Hoechst 33342 (H342)/propidium iodide (PI) for assessing bovine sperm vitality. Frozen-thawed semen (n = 30) of Holstein bulls was layeredon 40%/80% percoll solutions to isolate viable spermatozoa. An aliquot of viable spermatozoa was kept at 37°C (live sample); the rest was submitted to cold shock (dead sample). The two aliquots were mixed in three proportions, corresponding to 0%, 50% and100% of viable cells; the sperm vitality was analyzed. The percentages of viable spermatozoa evaluated with the four methods significantly correlated with the …

A Case Of Retroperitoneal Fibrosis Secondary To Chronic Periaortitis, Mariam Omar, Naushad Karim, Saeed Samnakay

Imaging & Diagnostic Radiology, East Africa

Retroperitoneal fibrosis is a rare inflammatory disorder causing increased fibrotic deposition in the retroperitoneum, often leading to ureteral obstruction. We present a case report of a 33-year-old male with 2-month history of back pain. Initial imaging showed thickening around the infrarenal aorta. Six months later the patient presented with renal failure; a CT abdomen revealed extensive soft tissue mass around the aorta resulting in ureteral obstruction. Histology results of biopsy of the soft tissue mass revealed retroperitoneal fibrosis. It is important for clinicians to treat periaortitis early as this can prevent progression to retroperitoneal fibrosis which can cause severe secondary …

Elucidating Under-Studied Aspects Of The Link Between Obesity And Multiple Myeloma: Weight Pattern, Body Shape Trajectory, And Body Fat Distribution, Catherine R Marinac, Catherine A Suppan, Edward Giovannucci, Mingyang Song, Ane S Kværner, Mary K Townsend, Bernard A Rosner, Timothy R Rebbeck, Graham A Colditz, Brenda M Birmann

2010-2019 OA Pubs

BACKGROUND: Although obesity is an established modifiable risk factor for multiple myeloma (MM), several nuanced aspects of its relation to MM remain unelucidated, limiting public health and prevention messages.

METHODS: We analyzed prospective data from the Nurses' Health Study and Health Professionals Follow-Up Study to examine MM risk associated with 20-year weight patterns in adulthood, body shape trajectory from ages 5 to 60 years, and body fat distribution. For each aforementioned risk factor, we report hazard ratios (HRs) and 95% confidence intervals (CIs) for incident MM from multivariable Cox proportional-hazards models.

RESULTS: We documented 582 incident MM cases during 4 …

Outcomes Of Bilateral Shoulder Arthroplasties: A Comparison Of Bilateral Total Shoulder Arthroplasties And Bilateral Reverse Shoulder Arthroplasties., Ryan Matthew Cox, Tyler James Brolin, Eric Michael Padegimas, Mark D. Lazarus, Charles Lonnie Getz, Matthew Lee Ramsey, Gerald Ross Williams, Joseph Albert Abboud

Rothman Institute Papers

Background: The purpose of this study was to compare outcomes of patients who underwent bilateral total shoulder arthroplasties (TSAs) for osteoarthritis (OA) versus bilateral reverse shoulder arthroplasties (RSAs) for cuff tear arthropathy (CTA).

Methods: Inclusion criteria were patients who underwent bilateral TSAs for OA or bilateral RSAs for CTA with at least 2 years of follow-up. Twenty-six TSA patients (52 shoulders) were matched 2 to 1 with 13 RSA patients (26 shoulders) by sex, age at first surgery, and time between surgeries. Outcomes measured were shoulder range of motion (ROM), complications, and patient-reported scores.

Results: Preoperatively, TSA patients had significantly …

Centeringpregnancy: Perceptions Of Providers And Staff In A Private Ob Practice, Allison F. Mills

Doctoral Dissertations and Projects

Traditional prenatal care has been the stalwart of care in the United States since the 1920s; however, a new model of care is emerging: group-style prenatal care. This model of care has been well-documented within literature as having notable maternal and fetal outcomes, including increased patient satisfaction, decreased preterm birth rates, increased breastfeeding rates, and increased patient compliance, to name only a few. With such remarkable outcomes, it begs the question of why the group prenatal care model is not more widely utilized. This project aimed to determine if increasing the knowledge of healthcare providers in a private obstetrics practice …

Addressing Childhood Undernutrition And Development Through Education And Lipid-Based Supplements, Jai K. Das, Rehana Salam

Department of Paediatrics and Child Health

No abstract provided.

Assessing Resident And Fellow Wellbeing And Burnout Levels: Lessons Learned From A Pilot Of The Ama Mini-Z Wellbeing Survey, Tanya A. Ensminger Ba, Margaret A. Hadinger Edd, Ms

Department of Education

No abstract provided.

Emerging Health Professionals: A Collaborative Strategy For Addressing Health Care Workforce Needs, Kerri Green Ms, Med., Margaret A. Hadinger Edd, Ms

Department of Education

No abstract provided.

The Impact Of Ocrelizumab On Immunoglobulin Levels And The Risk Of Infection., Kyle Smoot

Articles, Abstracts, and Reports

Background: Ocrelizumab (OCR), a CD20 antibody, was approved in the US in 2017 for the treatment of relapsing MS (RMS) and primary progressive MS (PPMS). In clinical trials, infection rates are higher in patients receiving OCR. Rituximab, which is very similar to OCR, has been reported to be associated with higher risk of infection particularly in patients with low levels of IgM or IgG.

Objective: To determine if low levels of IgM or IgG increase the risk of infection in patients treated with OCR.

Methods: MS patients in the OCR registry with at least one IgM/IgG value at doses 2, …

Quantifying Skin Photodamage With Spatial Frequency Domain Imaging: Statistical Results, Jeffrey B. Travers, Chien Poon, Trevor J. Bihl, Benjamin Rinehart, Christina E. Borchers, Daniel J. Rohrbach, Samia Borchers, Julian J. Trevino, Max Rubin, Heidi Donnelly, Karl Kellawan, Lydia Carpenter, Shalini Bahl, Craig A. Rohan, Elizabeth Muennich, Scott Guenthner, Holly Hahn, Ali Rkein, Marc Darst, Nico Mousdicas, Elizabeth E. Cates, Ulas Sunar

Dermatology Faculty Publications

We investigated the change in optical properties and vascular parameters to characterize skin tissue from mild photodamage to actinic keratosis (AK) with comparison to a published photodamage scale. Multi-wavelength spatial frequency domain imaging (SFDI) measurements were performed on the dorsal forearms of 55 adult subjects with various amounts of photodamage. Dermatologists rated the levels of photodamage based upon the photographs in blinded fashion to allow comparison with SFDI data. For characterization of statistical data, we used artificial neural networks. Our results indicate that optical and vascular parameters can be used to quantify photodamage and can discriminate between the stages as …

Diabetes-Related Amylin Dyshomeostasis: A Contributing Factor To Cerebrovascular Pathology And Dementia, Han Ly, Florin Despa

Pharmacology and Nutritional Sciences Faculty Publications

Type 2 diabetes (T2D) increases the risk for cerebrovascular disease (CVD) and dementia. The underlying molecular mechanisms remain elusive, which hampers the development of treatment or/and effective prevention strategies. Recent studies suggest that dyshomeostasis of amylin, a satiety hormone that forms pancreatic amyloid in patients with T2D, promotes accumulation of amylin in cerebral small blood vessels and interaction with Alzheimer's disease (AD) pathology. Overexpression of human amylin in rodents (rodent amylin does not form amyloid) leads to late-life onset T2D and neurologic deficits. In this Review, we discuss clinical evidence of amylin pathology in CVD and AD and identify critical …

The Effects Of Therapeutic Riding On Social Skills And Sensory Functioning In Children With Autism, Betsy Donahoe-Fillmore, Mary Insana Fisher, Christy Lee, Jordan Bevins, Cristin Carter, Stephanie Dailey, Kelsey Haynes, Allison Richard, Sarah Soboslay

Physical Therapy Faculty Publications

Purpose and Significance: Therapeutic riding (TR) is equine-assisted riding lessons that are adapted for people with a wide variety of impairments and is often used as an adjunct to traditional therapies. Previous research has shown that TR helped to improve sensory functioning, cognition and social skills in children with Autism Spectrum Disorder (ASD) but sessions have typically been for 10-12 weeks. The purpose of this study was to investigate if social skills and sensory functioning improved after only 8 weeks of TR.

Subjects: Children were recruited from a local TR center. Participants included seven children (5M, 2F) with a diagnosis …

Guidelines For Costing Of Social And Behavior Change Health Interventions, James Rosen, Willyanne Decormier Plosky, Lori Bollinger

Poverty, Gender, and Youth

These Guidelines for Costing of Social and Behavior Change Health Interventions (SBC Costing Guidelines) provide a framework for estimating the cost of interventions for social and behavior change, which seek to change health behaviors by addressing factors such as knowledge, attitudes, and social norms.

Patient And Provider Perspectives On Sexual History Taking During Gynecological Care: A Pilot Study In An Academic Family Medical Setting In New York City, Ashley M. Chastain

Dissertations and Theses

Background: In the United States (US), women face a number of serious issues concerning sexual health. Current surveillance data indicates that overall rates of bacterial sexually transmitted infections (STIs) are increasing rapidly. While rates of new diagnoses have decreased, the risks of acquiring HIV are still relatively high for some females, specifically Black/African-American women. In New York City (NYC), where this dissertation research was conducted, similar HIV/STI rates exist among females of reproductive age (aged 15-44). Among women in the US, there are also high estimated rates of other sexual health problems, such as sexual anxiety, sexual dysfunction, and intimate …

Long-Distance Axon Regeneration Promotes Recovery Of Diaphragmatic Respiratory Function After Spinal Cord Injury., Mark W. Urban, Biswarup Ghosh, Cole G. Block, Laura R. Strojny, Brittany A. Charsar, Miguel Goulão, Sreeya S. Komaravolu, George M. Smith, Megan C. Wright, Shuxin Li, Angelo C. Lepore

Farber Institute for Neuroscience Faculty Papers

Compromise in inspiratory breathing following cervical spinal cord injury (SCI) is caused by damage to descending bulbospinal axons originating in the rostral ventral respiratory group (rVRG) and consequent denervation and silencing of phrenic motor neurons (PhMNs) that directly control diaphragm activation. In a rat model of high-cervical hemisection SCI, we performed systemic administration of an antagonist peptide directed against phosphatase and tensin homolog (PTEN), a central inhibitor of neuron-intrinsic axon growth potential. PTEN antagonist peptide (PAP4) robustly restored diaphragm function, as determined with electromyography (EMG) recordings in living SCI animals. PAP4 promoted substantial, long-distance regeneration of injured rVRG axons through …

Patient Engagement On The Go: Utilizing Mobile Application Technology To Centralize Resources For Behavioral Health Patients, Paul A. Siegfried Ms, Jason Boyko Lpc, Faclp, Brenda Shaffer Msn, Rn, Edward R. Norris Md, Fapa, Fapm

Department of Psychiatry

No abstract provided.

Science Of Lifestyle; Strategies For Change, Raza Ur Rahman

Pakistan Journal of Neurological Sciences (PJNS)

Since the start of 21st century the focus of medical treatment is changing from curative to the preventive medicine and now functional recovery and quality of life are the outcome of curative medicine. These new outcomes of modern medicine can be achieved through adopting the strategies that enhance wellness of patient. The methods of enhancing wellness are in practice since centuries and their effectiveness has been handed down through word of mouth and tradition. They continue to evolve and were first documented in 1970s, by Canyon Ranch1, as a strategy to improve health through the principles of a healthy lifestyle. …

Post-Stroke Seizures: A Clinically Oriented Analysis, Sajid Hameed, Haris Hakeem, Mohammad Wasay

Pakistan Journal of Neurological Sciences (PJNS)

Stroke is an important cause of secondary epilepsy, especially in the elderly. Not only does this impact morbidity and mortality in an adverse way, it also prolongs the hospitalization. Various risk factors have been described in literature that increase the risk of seizures in a patient with stroke. Post stroke seizures fall on a spectrum of acute symptomatic and unprovoked seizures with varying pathophysiology and risk of subsequent development of epilepsy. Hence, the treatment approaches are also different. However, randomized controlled trials are lacking to guide monitoring and management strategies in post stroke seizures and the approaches remain individualized to …

An Overview Of Autism: Is It Treatable In Pakistan?, Tania Nadeem, Rabeeka Aftab, Nargis Asad

Pakistan Journal of Neurological Sciences (PJNS)

Autism Spectrum Disorder (ASD) is a clinically complex, pervasive neurodevelopmental disorder with early appearing social communication deficits and repetitive sensory–motor behaviors.1 Although affected individuals differ significantly from one another, typically the disorder is characterized by impairment in social reciprocity and communication. Children usually have speech delays or lack of social interaction including: lack of eye contact, limited response to name, decreased interest in peers, and restricted shared attention with parents.1 Autistic individuals also exhibit repetitive behaviors like flapping, lining, or stacking objects and narrowly focused rigid interests such as paying particular attention to spinning objects.1 It usually manifests before 3 …

What, When And For Whom Model Of Nutrition: A Health Management Approach, Muhammad Rafiq

Pakistan Journal of Neurological Sciences (PJNS)

Studies have shown that nutrition plays an important role in the pathophysiology of different health issues either physiological, or psychological. Nutrition is implicated in the development of health issues in different ways. The purpose of this mini review was to suggest a comprehensive model of nutrition, “What, When and for Whom Model of Nutrition”, in the light of existing literature. For this purpose, existing literature was explored to study the role of nutrition on mental health in perspective to, what type of nutrition, when it is consumed and/or who consumes it. Researchers concluded that it is not only what we …

Diagnostic Dilemmas Of Progressive Supranuclear Palsy, Humera Saeed, Qurat Ul Ain Khan, Syeda Masharab Jilani, Syeda Maheen Batool

Pakistan Journal of Neurological Sciences (PJNS)

In this report authors discuss similarities between psychiatric phenomenon i.e. catatonia and neuropsychiatric syndromes such as progressive supranuclear palsy (PSP) in a 51 years old male, known case of hypertension and diabetes, who presented to the psychiatric services with mutism, stereotypical movements of upper limbs, echolalia, anteriorly flexed neck, swallowing difficulty, decreased oral intake, urinary and fecal incontinence for a period of 1 year worsened for 6 months. Patient was initially treated for catatonia with benzodiazepines and electroconvulsive therapy but did not improve. A neuropsychiatric consultation was sought and a diagnosis of possible PSP was made according to the National …

The Natural Predominant Sleeping Positions In Cerebral Palsy; Does It Correlate With The Type Of Cerebral Palsy?, Sarah Razaq, Muhammad Aleem Arshad, Tahira Amjad

Pakistan Journal of Neurological Sciences (PJNS)

To see the natural positions of cerebral palsy subjects during sleep and their correlation with the particular type of cerebral palsy.

Tacrolimus-Associated Posterior Reversible Encephalopathy Syndrome In Allogenic Hematopoietic Stem Cell Transplant, Hina Imtiaz, Maryam Jamil Syed, Dureshahwar Kanwar, Bushra Taimuri, Sajid Hameed

Pakistan Journal of Neurological Sciences (PJNS)

Tacrolimus is an immunosuppressive drug used to lower the risk of transplant rejection in individuals after solid organ or hematopoietic transplantation. Cases of posterior reversible encephalopathy syndrome (PRES) as a complication of tacrolimus therapy are infrequently documented. The pathogenesis of this phenomenon is not well understood. Here, we report a case of an 18-year-old female with a history of acute myeloid leukemia that developed PRES after undergoing an allogeneic stem cell transplant and subsequent immunosuppressive therapy with tacrolimus.

Expert Search For The "Effect Of Dental Treatment Before Cardiac Valve Surgery", Kelly K. O'Brien

Expert Search Strategies

This search strategy was constructed to support the research for the peer reviewed article listed above. Full article abstract:

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