Medicine and Health Sciences Commons^™

Correlation Of Mothers With History Of Diabetes Mellitus And Infants With Anti-Gad65, Nanda Fadhilah Witris Salamy, Gadis Meinar Sari, Bambang Purwanto, Sulistiawati Sulistiawati

Folia Medica Indonesiana

The aim of this study was to analyze human sperm motility, viability, and morphology before and after cryopreservation. This true laboratory experimental study had pre and post randomized one group design. The study was conducted at the Embryology, Andrology, and Genetics Laboratory, Department of Medical Biology, Faculty of Medicine, Universitas Airlangga from August to November 2017. The eighteen samples of fresh semen were collected from male volunteers who agreed and signed the informed consent of the study. Samples were analyzed their motility, viability, and morphology before and after cryopreservation. Results of this study indicated differentiation between motility before and after …

Effectivity Of Erythropoietin-Alpha Between Fixed- And Adjusted-Dose In Chronic Kidney Disease Patients With Anemia On Hemodialysis, Mida Purwiningtyas, Yulistiani Yulistiani, Budi Suprapti, Bayu Dharma Santi

Folia Medica Indonesiana

Every year, there are 500.000 new cases and more than 250.000 deaths caused by cervical cancerworldwide. Cervical cancer patients faced physical and psychological problems several times that it activate stress mechanism such as hypothalamus-pituitary-adrenal (HPA) axis. These recurrent activations caused HPA axis disruption and adverse clinical effects. Several symptoms of endocrine stress response are the change of circadian cortisol rhythm. Cortisol is known as a stress hormone that involves an organism's response to stress and anxiety that influence the quality of life. This research aims to analyze the differences among serum cortisol level, anxiety, and quality of life in cervical …

Case Report: The Role Of Intravascular Ultrasonography In Patients Underwent Percutaneous Coronary Intervention, Yudi Her Oktaviono, Alisia Yuana Putri

Folia Medica Indonesiana

Resveratrol is an antioxidant that can be used as anti-aging. Topical use has several problems because solubility in water is low and unstable to light. This study aimed to evaluate the effect of the combination of soy bean oil and oleic acid liquid lipids on the characteristics, penetration, and stability of resveratrol nanostructured lipid carriers (NLC). Nanostructured lipid carriers (NLC) were made with high shear homogeneous technique. To determine the characterization of NLC, diffraction scanning calorimetry, X-ray diffraction, and Fourier transforms infrared spectrophotometry were used. Examination of the morphological form was carried out with a transmission electron microscope. The particle …

Professional Development For Clerkship Administrators: A 16-Year Overview Of The Clerkship Administrator Certificate Program, Donnita Pelser, Cathy Chavez, Lindsey Allison, Virginia Cleppe, Gary L Beck Dallaghan

Medical Education Faculty Publications

Background: Increasing accreditation requirements as well as transformations in medical school curricula necessitate administrative staff who are not only invested in the clerkship coordinator role but also view what they do as a career. To date, there has been a lack of professional development opportunities for clerkship administrators.

Methods: In 2003, the Central Group on Educational Affairs of the Association of American Medical Colleges recognized a need for professional development for clerkship administrators. The Clerkship Administrator Certificate Program emerged from that decision and presented for the first time in 2004 in Omaha, Nebraska. This article provides an overview of the …

A Case Of Ana-Negative Systemic Sclerosis Treated With Methylprednisolone, Carminda P. Rogacion, Veronica S, Uy, Reynaldo L. Ugalde, Emmerson Gale S. Vista

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Systemic sclerosis is a multi-systemic disease characterized by excessive fibrosis, inflammation, and vasculopathy. Common clinical features include skin thickening, telangiectasias, salt and pepper skin, beak-shaped nose, and microstomy. We report a case of ANA-negative systemic sclerosis in a male patient.

Case illustration: Our patient presented with a 10-month history of diffuse hyperpigmentation, skin tightening and decreased mouth aperture, accompanied by digital ulcers, hypopigmented macules and violaceous discoloration of the digits upon exposure to cold temperature. Punch biopsy done revealed mild acanthosis of the epidermis with basal cell layer hyperpigmentation, vacuolar alteration and thickening of the basement membrane …

Characteristics Of Habitat, Distribution, And Diversity Of Anopheles Spp In Kemelak Bindung Langit Village, Ogan Komering Ulu Regency, South Sumatra, Giri Maretasari, Yuanita Windusari, Syafrina Lamin, Laila Hanum, Dwi Septiawati

Journal of Environmental Science and Sustainable Development

Malaria is an infectious disease caused by Plasmodium andis transmitted through the bite of a female Anopheles vector. Ogan Komering Ulu (OKU) is a district in South Sumatra that is endemic to malaria. The study aims to determine habitat type, environmental factors that influence larvae development, and distribution of Anopheles larvae. The experiment was conducted from January to February 2019 in the Kelurahan Kemelak Bindung Langit, OKU. Species identification was carried out in the Entomology Laboratory, Baturaja Health Research and Development Center, OKU. Sampling locations were determined based on field observations, through simple purposive sampling. Identification of mosquito larvae which …

Comparison Of Antropometry And Physical Abilities Between Trained And Untrained Individuals In Second Growth Phase, Idzam Kholid Akbar, Bambang Purwanto, Hari Setijono

Folia Medica Indonesiana

Evaluations on Plasma Prothrombin Time (PPT) and Activated Partial Thromboplastin Time (APTT) are required in patients with Chronic Kidney Disease (CKD) stage V to determine the risk of bleeding after hemodialysis (HD) using heparin as the anticoagulant. This study aimed to compare the results of PPT and APTT in pre and post-hemodialysis patients with minimum dose of heparin. This was an observational-analytical study with cross-sectional design. The samples were collected in HD wards of Dr. Soetomo Hospital, Surabaya. There were 50 PPT and APTT samples collected from June to August 2017. The samples were evaluated using the tool CoaDATA 501. …

The Effect Of Cinnamomum Burmannii Water Extraction Against Staphylococcus Aureus, Enterobacter Spp., Pseudomonas Aeruginosa, And Candida Albicans: In Vitro Study, Bernadette Dian Novita, Silvia Sutandhio

Folia Medica Indonesiana

High-intensity exercise (3000-meter runner) contributes to muscle fatigue. Fatigue can be determined by measuring blood lactate levels. Blood lactate levels are a product of anaerobic metabolism. Lactate accumulation due to anaerobic physical activity can inhibit the glycolytic enzyme that affects decreased ATP production, damage of the calcium and sodium pumps in the muscles and causes fatigue. This study aimed to analyze the effect of vitamin E on the level of fatigue through the response of blood lactate levels in the runner 3000 meters. This research was a quasi-experimental research with a pretest-posttest design. Research subjects were 9 volunteer athletes (3000 …

The Expression Of E6 Hpv, P53 And P16ink4a At Well, Moderately, And Poorly Differentiated Cervical Adenocarcinoma, Gondo Mastutik, Alphania Rahniayu, Nila Kurniasari, Anny Setijo Rahaju, Rahmi Alia, Sjahjenny Mustokoweni

Folia Medica Indonesiana

Ethanol extract of leaves and petiole of pegagan (Centella asiatica) is potential as antimicrobial and antifertility. This study was to investigate whether ethanol extracts of leaf and petiole of Centella asiatica has potential as an antimicrobial and can decrease sperm quality and spermatogenic cells of mice. This was a randomized controlled study using Centella asiatica plant from which we made ethanol extract. The extract of the leaves and petiole of Centella asiatica was subjected to antimicrobial test using the bacteria S. aureus, S. epidermidis, and A. aerogenes. Then the observation was done after a 24-hour-old bacterial cultures by measuring the …

Case Report: Ventriculoperitoneal Shunt Catheter Migration And Transanal Extrusion In Persistent Vegetative State Adult Patient, Asra Al Fauzi, Muhammad Arifin Parenrengi, Joni Wahyuhadi, Eko Agus Subagio, Agus Turchan

Folia Medica Indonesiana

Hyaluronic acid (HA) is a glycosaminoglycan with a straight-chain polymer arrangement defined as the extracellular matrix constituent. High molecular weight HA has normal physicochemical, biological, and physiological properties whereas low molecular weight has the property of angiogenesis, inflammation, and suppresses apoptosis. This study occupied the samples of 35 paraffin block from poorly and well differentiated retinoblastoma tissue and 8 normal retinal block which have been collected for 4 years from 2010-2013 at Dr. Soetomo Hospital, Surabaya, Indonesia. Afterwards, the paraffin blocks were immunohistochemically examined for HA staining, expression of cell proliferation (Ki-67), and cell apoptosis to determine intratumoral aggressiveness of …

Association Between Obesity And History Of Atopy With Atopic Dermatitis In Children: A Cross-Sectional Study, Putu Nila Wardhani Batan, Ariana Ariana, Made Wardhana

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: The prevalence of atopic dermatitis (AD) has rapidly increased in the past 4 decades and has been mostly observed in children. The prevalence of obesity has also significantly increased worldwide, suggesting that the two conditions may be associated.

Methods: This retrospective analytic study involved a cross-sectional design and used secondary data taken from the medical record of patients who visited the Pediatric Dermatology Subdivision at Dermatology and Venereology Polyclinic Sanglah General Hospital from January 2015 to December 2015. Thirty-two samples were selected.

Results: The prevalence ratio of obesity among subjects with AD was 2.178 (95% CI …

Research News. Grants, 2019. Volume 4, University Of Mississippi. School Of Pharmacy, Soumyajit Majumdar

Grants (2015-)

Grants and contracts awarded during October-December 2019

Predictive Modeling Of Influenza In New England Using A Recurrent Deep Neural Network, Alfred Amendolara

Theses

Predicting seasonal variation in influenza epidemics is an ongoing challenge. To better predict seasonal influenza and provide early warning of pandemics, a novel approach to Influenza-Like-Illness (ILI) prediction was developed. This approach combined a deep neural network with ILI, climate, and population data. A predictive model was created using a deep neural network based on TensorFlow 2.0 Beta. The model used Long-Short Term Memory (LSTM) nodes. Data was collected from the Center for Disease Control, the National Center for Environmental Information (NCEI) and the United States Census Bureau. These parameters were temperature, precipitation, wind speed, population size, vaccination rate and …

Effect Of 3d Printed Tablet Shape On Drug Release Profile, Christina Gedeon

Theses

There is a growing interest in utilizing additive manufacturing (AM) as a manufacturing tool to develop oral tablets for personalized medicine. This ultimate goal in mind, this study explores the feasibility of extrusion-based fused deposition modeling (FDM) to 3D print oral tablets with tunable design to control drug release profile. Tablets are printed using poly(vinyl alcohol) (PVA) loaded with model drugs: acetaminophen and caffeine. Hot melt extrusion (HME) is used to fabricate PVA filaments loaded with acetaminophen and caffeine. These filaments are used to fabricate a range of tablets with varying designs to prepare immediate and delayed release tablets. Thermal …

Psychoeducation “Aku Peduli” For Parent With Typically Developing Children At An Inclusive Kindergarten, Andi Nur Zamzam Arman, Farida Kurniawati

ASEAN Journal of Community Engagement

This study examined the effectiveness of “AKU PEDULI” psychoeducation in helping the parents of typically developing children to increase their knowledge of special needs children and inclusive education at an inclusive kindergarten. “AKU PEDULI” is abbreviated from Anak Berkebutuhan Khusus dan Pendidikan Inklusif (Special Needs Children & Inclusive Education). Quantitative methods were used in both the pre-test and post-test parts of the research. Six mothers aged 28–34 years, of typically developing children were selected to participate in the study through accidental sampling. Participants were required to be parents of typically developing children who attend an inclusive kindergarten and who have …

Patient Safety Smartphone Application For Quality Assurance In Primary Healthcare Facilities, Levina Chandra Khoe, Ajeng Pramastuty, Boy Subirosa Sabarguna, Herquranto Herqutanto

ASEAN Journal of Community Engagement

In order to achieve high-quality healthcare, patient safety should be improved and monitored regularly. Moreover, accreditation on healthcare facilities is being requested in recent years. Mobile application can serve as a tool for community healthcare centre’s (Puskesmas) to assess their accreditation score, especially patient safety. To provide as a tool for self-monitoring for patient safety elements. This is a case-based article focuses on the development of smartphone application using the input-process-output-outcome scheme as the framework. We reviewed regulation of health minister on Puskesmas accreditation and developed a checklist and scoring for patient safety components. This is the first mobile application …

Connectivity Differences Between Gulf War Illness (Gwi) Phenotypes During A Test Of Attention, Tomas Clarke, Jessie Jamieson, Patrick Malone, Rakib U. Rayhan, Stuart Washington, John W. Vanmeter, James N. Baraniuk

Department of Mathematics: Faculty Publications

One quarter of veterans returning from the 1990–1991 Persian Gulf War have developed Gulf War Illness (GWI) with chronic pain, fatigue, cognitive and gastrointestinal dysfunction. Exertion leads to characteristic, delayed onset exacerbations that are not relieved by sleep. We have modeled exertional exhaustion by comparing magnetic resonance images from before and after submaximal exercise. One third of the 27 GWI participants had brain stem atrophy and developed postural tachycardia after exercise (START: Stress Test Activated Reversible Tachycardia). The remainder activated basal ganglia and anterior insulae during a cognitive task (STOPP: Stress Test Originated Phantom Perception). Here, the role of attention …

Histopathological Diagnosis Of Diseases Affecting Amphibians Inhabiting Kihansi Gorge, Tanzania, Joshua J Malago

Tanzania Journal of Science

Kihansi gorge is a natural habitat to Kihansi spray toad (KST), Nectophrynoides asperginis. The toad is extinct in its natural habitat partly due to diseases. Efforts to successfully re-introduce it are primed by awareness and mitigation of prevalent diseases at the gorge. This study aimed at exploring the prevalent amphibian diseases at and around Kihansi gorge. A total of 182 individuals from Petropedetes yakusini (n = 60), Nectophrynoides tornieri (n = 60) and Leptopelis uluguruensis (n = 62) species were collected, humanely sacrificed, fixed in formalin, routinely processed, sectioned, stained with haematoxylin and eosin and analysed for diseases by histopathology. …

Determinants Of Stroke Inpatient Charge In Chronic Rehabilitation Wards Of A Community Hospital In Taiwan, Allen C.L. Hsu, Miao-Ming Chen, Chih-Kuang Chen

Rehabilitation Practice and Science

Stroke is a disease with severe consequences which impose a considerable socio-economic burden on patients and society. In developed countries, stroke patients alone generate about 3-4% of the direct costs within the healthcare system. The costs of rehabilitation and long-term care of disabled stroke survivors are expected to rise even further because of the increasing number of the aging population and declining stroke case-fatality rates. The aims of the paper are to evaluate the factors that may influence costs of stroke patients in chronic rehabilitation wards for better management of medical resources. This study was conducted at a local general …

Shoulder And Upper Extremities Function In Patients With Head And Neck Cancer After Selective Neck Dissection, Han-Chin Hsieh, Chau-Peng Leong, Yan-Yuh Lee, Chih-Yen Chien, Chia-Hsuan Lin, Yu-Chi Huang

Rehabilitation Practice and Science

Background: Shoulder dysfunction is common after nerve-sparing selective neck dissection (SND). We aimed to assess the upper extremity function and shoulder pain in patients with head and neck cancer (HNC) after SND. Methods: In this cross-sectional study, we enrolled 38 patients with HNCs after SND and evaluated shoulder active range of motion (ROM), muscle strength, pain, and the Disabilities of the Arm, Shoulder and Hand Score (DASH) questionnaire for upper extremity function on operative and non-operative sides. Results: Significant reductions in shoulder motions, muscle strength, and higher level of shoulder pain were observed on the operative side after SND. Worse …

Elastic Band Training Improves Adiposity And Physical Performance In Adults With Prader-Willi Syndrome: A Pilot Study, Valeria Chiu, Sheng-Hsun Chou, Hsin-Chi Wu, I-Shiang Tzeng, Che-Yi Chao, Pei-Jung Huang, Li-Ping Tsai

Rehabilitation Practice and Science

OBJECTIVE: The aim of this study was to investigate the changes in the regional fat distribution of body composition and the physical performance of adults with Prader-Willi syndrome (PWS) after progressive elastic band (EB) training. METHODS: Participants were trained three times per week, performing three sets of 15-20 repetitions for each of the exercises with EB for 24 weeks. Changes in body composition were measured using dual-energy X-ray absorptiometry. Physical performance was assessed by determination of hand grip strength, the timed up-and-go test, the 30-second chair stand test, the 2-minute step test, and the Berg Balance Scale. RESULTS: Six participants …

Cytomegalovirus Infection Complicated With Severe Rhabdomyolysis And Dysphagia: A Casereport And Literature Reviewarticle, Heng-An Yeh, Yu-Jen Chen, Jean-Lon Chen

Rehabilitation Practice and Science

Cytomegalovirus(CMV) is a common virus that usually occurs in immunocompromised patients. After primary infection with CMV, the virus becomes latent in multiple organs and can later be reactivated during severe immune system dysregulation. Rhabdomyolysis is a disease of human muscle cell necrosis, and the rapid dissolution of damaged or injured muscles may lead to acute kidney injury or multiple organ failure. After reviewarticleing relevant literature, patients with severe rhabdomyolysis caused by CMV infection are rarely reported and even less commonly, CMV leads to severe dysphagia. The patient was a 35-year-old woman without underlying disease. Two months before hospitalization,she visited the …

Treatment Of Multibacillary Leprosy Following The Development Of Dapsone Hypersensitivity Syndrome, Sudarsono Sudarsono

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: World Health Organization (WHO) multi-drug therapy (MDT) is the current standard treatment for leprosy. A wide range of frequency of adverse effects caused by MDT has been reported. Dapsone hypersensitivity syndrome (DHS) is a serious adverse effect caused by dapsone. Prompt withdrawal of dapsone is important aspect in the management of DHS. Alternative regimens are needed to treat leprosy patient with DHS.

Case Illustration: A 37-year-old man with multibacillary (MB) leprosy developed DHS in 39 days after the initiation of WHO MDT. Dapsone was withdrawn and methylprednisolone of 75 mg/day was prescribed. Twelve days after admission the …

Prevalence And Risk Factors Of Bacterial Vaginosis Among Female Sex Workers In Surakarta, Rini Hastuti, Danu Yuliarto, Agung Triana, Willa Damayanti, Rakhma Tri Irfanti, Mardiana Mardiana, Putti Fatiharani Dewi, Ambar Aliwardani, Ervianti Abas, Sulistyo Sulistyo, Prasetyadi Mawardi, Endra Yustin Ellistasari

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Bacterial vaginosis (BV) is the most common vaginal infection in women of reproductive age and increases the risk of acquiring human immunodeficiency virus (HIV) and other sexually transmitted diseases (STDs). Data regarding the association between sexual activity and BV acquisition is contradictory. Thus, tracking the prevalence and associated risk factors of BV among female sex workers (FSWs) is necessary to improve our understanding and control of STDs and the HIV epidemic.

Methods: The subjects of this study were FSWs in Surakarta. This study adopted a cross-sectional design, and diagnosis was established using Amsel criteria. Interviews were conducted …

The Epidemiology Of Skin Cancer At Dr. Cipto Mangunkusumo National Central General Hospital From 2014 To 2017, Larisa Paramitha Wibawa, Melody Febriana Andardewi, Inge Adi Kristanti, Riesye Arisanty

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: The incidence of skin cancer has been increasing over the past decades globally. At present, there is no valid national cancer data in Indonesia. The purpose of this study is to evaluate the increment of skin cancer cases at Dr. Cipto Mangunkusumo National General Hospital, Jakarta.

Methods: In this retrospective descriptive study, we evaluated all pigmented skin tumor cases from June 2014 to June 2017. Data were obtained from the Department of Anatomical Pathology and medical records at Dr. Cipto Mangunkusumo National General Hospital. Data were compared with previous reports.

Results: From 263 skin cancer cases, …

Langerhans Cell Histiocytosis: Diagnosis And Management, Lusiana Lusiana, Hikari Ambara Sjakti, Githa Rahmayunita, Tjut Nurul Alam Jacoeb, Inge Ade Krisanti

Journal of General - Procedural Dermatology and Venereology Indonesia

Langerhans cell histiocytosis (LCH) is a rare disorder characterized by abnormal clonal proliferation of Langerhans dendritic cells. The incidence of LCH is 1 to 3 cases per 1 million children worldwide, and occurs most frequently in children of 1–4 years of age. The etiopathogenesis of LCH, whether it is neoplastic or reactive, is still controversial. Langerhans cell histiocytosis has a wide spectrum of clinical features, and dermatological abnormalities usually occur early. The most frequent lesions are elevated yellowish-red translucent papules about 1–2 mm in diameter and generally located in seborrheic areas. The most recent classification (the Histiocyte Society study 2017) …

The Use Of Systemic Medications In Pediatric Dermatoses: A Review, Shanthi Narla, Githa Rahmayunita, Rinadewi Astriningrum, Tor Shwayder, Ariyati Yosi, Henry W. Lim

Journal of General - Procedural Dermatology and Venereology Indonesia

Research has begun to illustrate a favorable efficacy and side-effect profile for many systemic agents used in pediatric dermatological conditions (i.e. atopic dermatitis, psoriasis, scleroderma, alopecia areata, chronic spontaneous urticaria, autoimmune blistering disorders, and hidradenitis suppurativa) despite not having extensive randomized clinical trials. The purpose of this article is to summarize the available data on the treatment regiments, safety, and efficacy of systemic immunosuppressants, including the newer biologics, focusing on the most up-to-date systematic reviews or randomized clinical trials. The review demonstrates that many of the present studies lack data on long-term efficacy and consist of small patient populations. Further …

Recurrent Basal Cell Carcinoma With Maxillary Bone Invasion, Adhimukti T. Sampurna, Eva Riani, Inge Ade Kristanti, Yayi Dwina, Kuniaki Ohara

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Basal cell carcinoma (BCC) is a malignant, slow growing, and locally invasive skin tumor. Advanced and neglected BCC may invade adjacent structures. The 5-year recurrence rates of facial BCCs are 4.1% after excision and 2.5% after Mohs Micrographic Surgery (MMS). The number of BCC cases invading the bones of the head and neck region is limited.

Case Illustration: A 75-year-old male complained of bleeding and ulcer enlargement on the right cheek expanding to the right nasal ala for 1 month. The patient had a history of an enlarged and painful lenticular nodule with a hyperpigmented spot that …

The Correlation Between Icaa And Icad Genes With Biofilm Formation Staphylococcus Epidermidis In Vitro, Dian Rachmawati, Kuntaman Kuntaman, Lindawati Alimsardjono

Folia Medica Indonesiana

This study was conducted to identify the presence of icaA and icaD genes in S. epidermidis and to analyze the relationship between the presence of icaA and icaD genes with the ability of in vitro biofilm formation in S. epidermidis. S. epidermidis isolates from patients and healthy people were collected and PCR was examined to detect icaA and icaD genes. which then continued to examine the ability of biofilm formation by the method of Congo Red Agar. The results of this genotypic and phenotypic examination were then tested for correlation with statistical tests using SPSS 23.0. A total of 40 …

The Effect Of Subconjunctival Bevacizumab On Angiogenesis In Rabbit Model, Nurwasis Nurwasis, Diana Yuliawati, Evelyn Komaratih, Heriyawati Heriyawati

Folia Medica Indonesiana

Bone is an important organ for supports the body that stores reserve of calcium, phosphorus, and other minerals. In fracture conditions where bleeding, soft tissue edema, nerve damage, and blood vessels around the bone damage happen, they can cause the mobilization of these minerals in the surrounding tissue. One of the efforts made in the treatment of these fractures is reconnection, in which it works by filling of bone defect with a matrix and administration of anti-infection. Biomaterial filling in defective bone is thought to accelerate the healing process of bone fracture and prevent osteomyelitis. For this reason, this study …