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Articles 14131 - 14160 of 16114
Full-Text Articles in Medicine and Health Sciences
Watch Your Children Grow: Learning How To Address Obesity In Underserved Populations, Meredith Lewis, Denise Surina-Baumgartner, Shivani Malhotra, Rajalakshmi Cheerla
Watch Your Children Grow: Learning How To Address Obesity In Underserved Populations, Meredith Lewis, Denise Surina-Baumgartner, Shivani Malhotra, Rajalakshmi Cheerla
UAB Huntsville Research Day - All Presentations
2019 oral presentation
Mind The Gap: Experimental Tests To Improve Efficacy Of Fladry For Nonlethal Management Of Coyotes, Julie K. Young, John Draper, Stewart Breck
Mind The Gap: Experimental Tests To Improve Efficacy Of Fladry For Nonlethal Management Of Coyotes, Julie K. Young, John Draper, Stewart Breck
United States Department of Agriculture Wildlife Services: Staff Publications
Coyotes (Canis latrans) are the top predator of livestock in the contiguous United States. Developing more effective nonlethal tools to prevent coyote depredation will facilitate coexistence between livestock producers and coyotes. Fladry is a nonlethal deterrent designed to defend livestock by creating a visual barrier to wolves (C. lupus). Fladry may also be effective with coyotes, but large gap spacing between flags may reduce its efficacy. To address this issue, we performed 2 experiments on captive coyotes using fladry modified to reduce gap spacing at the U.S. Department of Agriculture, Predator Research Facility in Millville, Utah, USA, during 2015–2016 and …
What Are The Transmission Mechanisms Of Influenza A Viruses In Wild Mammals?, J. Jeffrey Root
What Are The Transmission Mechanisms Of Influenza A Viruses In Wild Mammals?, J. Jeffrey Root
United States Department of Agriculture Wildlife Services: Staff Publications
Some influenza A viruses (IAVs) represent serious potential threats to public and agricultural health, with 3 notable examples from the past decade. During 2009, a novel H1N1 IAV (A[H1N1]pdm09), which was first detected in the United States, spread rapidly throughout many regions of the world. In the United States alone, the Centers for Disease Control and Prevention estimated that >60 million human cases were associated with this emergent and pandemic virus. During 2013, a novel H7N9 avian-origin IAV (Asian lineage avian influenza A[H7N9] virus) was first detected in China. This virus not only cost the poultry industry more than $1 …
Analysis Of Iophenoxic Acid Analogues In Small Indian Mongoose (Herpestes Auropunctatus) Sera For Use As An Oral Rabies Vaccination Biological Marker, Are R. Berentsen, Robert T. Sugihara, Cynthia G. Payne, Israel Leinbach, Steven F. Volker, Ad Vos, Steffen Ortmann, Amy T. Gilbert
Analysis Of Iophenoxic Acid Analogues In Small Indian Mongoose (Herpestes Auropunctatus) Sera For Use As An Oral Rabies Vaccination Biological Marker, Are R. Berentsen, Robert T. Sugihara, Cynthia G. Payne, Israel Leinbach, Steven F. Volker, Ad Vos, Steffen Ortmann, Amy T. Gilbert
United States Department of Agriculture Wildlife Services: Staff Publications
The small Indian mongoose (Herpestes auropunctatus) is a reservoir of rabies virus (RABV) in Puerto Rico and comprises over 70% of animal rabies cases reported annually. The control of RABV circulation in wildlife reservoirs is typically accomplished by a strategy of oral rabies vaccination (ORV). Currently no wildlife ORV program exists in Puerto Rico. Research into oral rabies vaccines and various bait types for mongooses has been conducted with promising results. Monitoring the success of ORV relies on estimating bait uptake by target species, which typically involves evaluating a change in RABV neutralizing antibodies (RVNA) post vaccination. This …
Carrion Availability In Space And Time, Marcos Moleón, Nuria Selva, David M. Bailey, David M. Bailey, Ainara Cortés-Avizanda, Travis L. Devault
Carrion Availability In Space And Time, Marcos Moleón, Nuria Selva, David M. Bailey, David M. Bailey, Ainara Cortés-Avizanda, Travis L. Devault
United States Department of Agriculture Wildlife Services: Staff Publications
Introduction
Availability of carrion to scavengers is a central issue in carrion ecology and management, and is crucial for understanding the evolution of scavenging behaviour. Compared to live animals, their carcasses are relatively unpredictable in space and time in natural conditions, with a few exceptions (see below, especially Sect. “Carrion Exchange at the Terrestrial-Aquatic Interface”). Carrion is also an ephemeral food resource due to the action of a plethora of consumers, from microorganisms to large vertebrates, as well as to desiccation (i.e., loss of water content; DeVault et al. 2003; Beasley et al. 2012; Barton et al. 2013; Moleón et …
Comparing Live-Capture Methods For Nutria: Single- Versus Multiple-Capture Cage Traps, Trevor R. Sheffels, Mark D. Sytsma, Jacoby Carter, Jimmy D. Taylor
Comparing Live-Capture Methods For Nutria: Single- Versus Multiple-Capture Cage Traps, Trevor R. Sheffels, Mark D. Sytsma, Jacoby Carter, Jimmy D. Taylor
United States Department of Agriculture Wildlife Services: Staff Publications
Herbivory and burrowing by nutria (Myocastor coypus) cause substantial ecological and economic damage. Trapping is a common, effective practice for reducing nutria damage; however, trapping approaches must continually be adapted to keep pace with evolving animal welfare and ethical issues and to more effectively target pest species of interest. Our objective was to evaluate the efficacy of 2 nonlethal trap types for nutria: single-capture (SCT) and multi-capture (MCT) cage traps. We established 3 MCTs and 3 SCTs at each of 7 sites on a 10,500-ha mixed-use island located 15 km northwest of Portland, Oregon, USA. We pre-baited using carrots, apples, …
Biology And Impacts Of Pacific Island Invasive Species. 15. Psittacula Krameri, The Rose-Ringed Parakeet (Psittaciformes: Psittacidae)1, Aaron B. Shiels, Nicholas P. Kalodimos
Biology And Impacts Of Pacific Island Invasive Species. 15. Psittacula Krameri, The Rose-Ringed Parakeet (Psittaciformes: Psittacidae)1, Aaron B. Shiels, Nicholas P. Kalodimos
United States Department of Agriculture Wildlife Services: Staff Publications
The rose-ringed parakeet (RRP), Psittacula krameri, has become established in at least four Pacific Island countries (Hong Kong China, Japan, New Zealand, U.S.A.), including the Hawaiian islands of Kaua‘i, O‘ahu, and Hawai‘i. Most Pacific islands are at risk of RRP colonization. This species was first introduced to Hong Kong in 1903 and Hawai‘i in the 1930s–1960s, established since 1969 in Japan, and in New Zealand since 2005 where it has repeatedly established after organized removals. The founding birds were imported cage-birds from the pet trade. In native India, RRP are generally found associated with human habitation and are considered a …
Animal-Assisted Interventions In Health Care Settings: A Best Practices Manual For Establishing New Programs, Sandra B. Barker, Rebecca A. Vokes, Randolph T. Barker
Animal-Assisted Interventions In Health Care Settings: A Best Practices Manual For Establishing New Programs, Sandra B. Barker, Rebecca A. Vokes, Randolph T. Barker
Purdue University Press Book Previews
Growing literature around the benefits of animal-assisted intervention (AAI) spurs health care professionals and administrators to start new programs. Yet the trend also raises questions of how best to begin and run successful AAI programs—under what circumstances, with what staff, and within what guidelines.
Animal-Assisted Interventions in Health Care Settings: A Best Practices Manual for Establishing New Programs succinctly outlines how best to develop, implement, run, and evaluate AAI programs. Drawing on extensive professional experiences and research from more than fifteen years leading the Center for Human-Animal Interaction in the Virginia Commonwealth University School of Medicine, the authors discuss both …
Recurrent Falls In A Patient With Suspected Ovarian Cancer: A Rare Case Of Lower Extremity Weakness, Noaman Ahmad, Aadil Lodhi, Ali Hassoun
Recurrent Falls In A Patient With Suspected Ovarian Cancer: A Rare Case Of Lower Extremity Weakness, Noaman Ahmad, Aadil Lodhi, Ali Hassoun
UAB Huntsville Research Day - All Presentations
2019 clinical vignette poster
Septic Knee Monoarthritisdue To Histoplasma Capsulatum After Bone Marrow Transplant In A Patient With Aplastic Anemia, Bhavyaa Bahl, Lourdes Corman
Septic Knee Monoarthritisdue To Histoplasma Capsulatum After Bone Marrow Transplant In A Patient With Aplastic Anemia, Bhavyaa Bahl, Lourdes Corman
UAB Huntsville Research Day - All Presentations
2019 clinical vignette poster
Virginia Dental Journal (Vol. 96, No. 1, 2019)
Virginia Dental Journal (Vol. 96, No. 1, 2019)
Virginia Dental Journal
No abstract provided.
The Flow: Educate. Empower. Change, Kirsten Tucker, Shaylee Ragar, Madison Haynes, Lea Graham, Monica Paul
The Flow: Educate. Empower. Change, Kirsten Tucker, Shaylee Ragar, Madison Haynes, Lea Graham, Monica Paul
Undergraduate Theses, Professional Papers, and Capstone Artifacts
Menstruation is often misrepresented, stigmatized, and ignored. A lack of education and distorted view of periods in society greatly impacts young menstruators as they begin to have periods and can have long-term negative effects on their physical, mental, and emotional well-being. In order to design a project that effectively addressed this global problem, we used the Human Centered Design approach. This process has three steps: Inspiration, Ideation, and Implementation. During the Inspiration phase, we conducted expert interviews with professionals in the field of menstrual health and completed a literature review to further our understanding of the issues facing menstruators. After …
The Importance Of Early Intervention And Education For Caregivers Of Children With Hereditary Tyrosinemia, Sarah Bonnell
The Importance Of Early Intervention And Education For Caregivers Of Children With Hereditary Tyrosinemia, Sarah Bonnell
Summer Community of Scholars Posters (RCEU and HCR Combined Programs)
No abstract provided.
Metabolomic Analysis Of Urine From A Rat Model Relevant To Diabetes Using Nmr, Anna Hart
Metabolomic Analysis Of Urine From A Rat Model Relevant To Diabetes Using Nmr, Anna Hart
Summer Community of Scholars Posters (RCEU and HCR Combined Programs)
No abstract provided.
Antibacterial Efficacy Of Nanocarriers Designed To Target Pseudomonas Aeruginosa, Anna Mcalpin
Antibacterial Efficacy Of Nanocarriers Designed To Target Pseudomonas Aeruginosa, Anna Mcalpin
Summer Community of Scholars Posters (RCEU and HCR Combined Programs)
No abstract provided.
Visualizations For Cartilage Restoration Method, Klayton Riley
Visualizations For Cartilage Restoration Method, Klayton Riley
Summer Community of Scholars Posters (RCEU and HCR Combined Programs)
No abstract provided.
Promoting Heart Healthy Behavior In Adolescents At The Boys And Girls Club, Morgan Tomasiewicz
Promoting Heart Healthy Behavior In Adolescents At The Boys And Girls Club, Morgan Tomasiewicz
Summer Community of Scholars Posters (RCEU and HCR Combined Programs)
No abstract provided.
How Coping Process Relates To Eating Behaviors Among Military Veterans With Posttraumatic Stress Disorder, Debra Kimberlin
How Coping Process Relates To Eating Behaviors Among Military Veterans With Posttraumatic Stress Disorder, Debra Kimberlin
Graduate Research Theses & Dissertations
Posttraumatic stress disorder (PTSD) is a mental health condition faced by many veterans, and veterans with PTSD have higher rates of poor health and obesity than civilians. Evidence suggests mental health issues such as PTSD may be associated with disordered eating behaviors. In addition, veterans with PTSD may select a variety of coping behaviors to manage stress and emotions, some of which may negatively impact their health. This study explored the relationships between coping process, emotion- and stress-related eating, and eating disorder risk among a sample of veterans with PTSD (n = 239) who were recruited through veteran service organizations …
Equity In Starting Salaries: A Tangible Effort To Achieve Gender Equity In Medicine, Esther Choo, David R. Bangsberg
Equity In Starting Salaries: A Tangible Effort To Achieve Gender Equity In Medicine, Esther Choo, David R. Bangsberg
OHSU-PSU School of Public Health Faculty Publications and Presentations
Letter to the Editor.
In 2017, for the first time, more women than men enrolled in medical school, marking a pivotal moment for setting and achieving reasonable goals for gender equity in medicine.
Inequity in compensation is a key target: The gender pay gap begins upon first hire, is not explained by part-time work or choice of specialty, and compounds over time. In a 2016 Wall Street Journal analysis, female physicians earned only 64.5% of what male physicians earned, the largest disparity amongst the 446 occupations examined. In its 2018 compensation report, Doximity reported an average physician gender gap of …
Female Sex And Cardiovascular Disease Risk In Rural Uganda: A Cross-Sectional, Population-Based Study, Itai M. Magodoro, Maggie Feng, Crystal North, Dagmar Vořechovská, John D. Kraemer, Bernard Kakuhikire, David Bangsberg, Alexander C. Tsai, Mark J. Siedner
Female Sex And Cardiovascular Disease Risk In Rural Uganda: A Cross-Sectional, Population-Based Study, Itai M. Magodoro, Maggie Feng, Crystal North, Dagmar Vořechovská, John D. Kraemer, Bernard Kakuhikire, David Bangsberg, Alexander C. Tsai, Mark J. Siedner
OHSU-PSU School of Public Health Faculty Publications and Presentations
Background:
Sex-based differences in cardiovascular disease (CVD) burden are widely acknowledged, with male sex considered a risk factor in high-income settings. However, these relationships have not been examined in sub- Saharan Africa (SSA). We aimed to apply the American Heart Association (AHA) ideal cardiovascular health (CVH) tool modified by the addition of C-reactive protein (CRP) to examine potential sex-based differences in the prevalence of CVD risk in rural Uganda.
Methods: In a cross-sectional study nested within a population-wide census, 857 community-living adults completed physical and laboratory-based assessments to calculate individual ideal CVH metrics including an eight category for CRP levels. …
Evaluation Of Cross-Reactivity To Taenia Hydatigena And Echinococcus Granulosus In The Enzyme-Linked Immunoelectrotransfer Blot Assay For The Diagnosis Of Porcine Cysticercosis, Lucho Gomez-Puerta, Ana Vargas-Calla, Yesenia Castillo, Maria Teresa Lopez-Urbina, Pierre Dorny, Hector H. Garcia, Armando E. Gonzalez, Seth E. O'Neal
Evaluation Of Cross-Reactivity To Taenia Hydatigena And Echinococcus Granulosus In The Enzyme-Linked Immunoelectrotransfer Blot Assay For The Diagnosis Of Porcine Cysticercosis, Lucho Gomez-Puerta, Ana Vargas-Calla, Yesenia Castillo, Maria Teresa Lopez-Urbina, Pierre Dorny, Hector H. Garcia, Armando E. Gonzalez, Seth E. O'Neal
OHSU-PSU School of Public Health Faculty Publications and Presentations
Background:
Taenia solium is an important zoonotic parasite that infects humans as definitive host (taeniasis) and pigs as intermediate host (cysticercosis). Serological diagnosis of porcine cysticercosis is limited to antigen detection using ELISA, which is known to cross-react with other Taenia species, and antibody detection using the lentil-lectin glycoprotein enzyme-linked immunoelectrotransfer blot (LLGP EITB), which has not been adequately evaluated for cross-reactivity to other parasites. Field studies suggest that the GP50 diagnostic band of the LLGP EITB may crossreact to Taenia hydatigena, a common non-zoonotic parasitic infection of pigs. The objective of this study was to evaluate the specificity of …
Cardiovascular Risk Factors Associated With Venous Thromboembolism, John Gregson, Stephen Kaptoge, Thomas Bolton, Lisa Pennells, Peter Willeit, Carlos J. Crespo, Multiple Additional Authors
Cardiovascular Risk Factors Associated With Venous Thromboembolism, John Gregson, Stephen Kaptoge, Thomas Bolton, Lisa Pennells, Peter Willeit, Carlos J. Crespo, Multiple Additional Authors
OHSU-PSU School of Public Health Faculty Publications and Presentations
Importance It is uncertain to what extent established cardiovascular risk factors are associated with venous thromboembolism (VTE).
Objective To estimate the associations of major cardiovascular risk factors with VTE, ie, deep vein thrombosis and pulmonary embolism.
Design, Setting, and Participants This study included individual participant data mostly from essentially population-based cohort studies from the Emerging Risk Factors Collaboration (ERFC; 731 728 participants; 75 cohorts; years of baseline surveys, February 1960 to June 2008; latest date of follow-up, December 2015) and the UK Biobank (421 537 participants; years of baseline surveys, March 2006 to September 2010; latest date of follow-up, February …
Geospatial-Temporal, Demographic, And Programmatic Adoption Characteristics Of A Large-Scale Water Filter And Improved Cookstove Intervention In Western Province, Rwanda, Katie Fankhauser, Corey L. Nagel, Christina Barstow, Miles Kirby, Evan A. Thomas
Geospatial-Temporal, Demographic, And Programmatic Adoption Characteristics Of A Large-Scale Water Filter And Improved Cookstove Intervention In Western Province, Rwanda, Katie Fankhauser, Corey L. Nagel, Christina Barstow, Miles Kirby, Evan A. Thomas
OHSU-PSU School of Public Health Faculty Publications and Presentations
Lowering the global disease burden of preventable disease has been addressed in part by the distribution of health products and behavior change campaigns in low-income countries. Realizing a health impact requires adoption by participants, and the topic of program uptake and sustained adoption has been studied extensively, although an ecological context is largely missing from existing work. This study characterizes self-reported and observed adoption of improved cookstoves and point-of-use water filters among nearly 80,000 households in Rwanda using demographic and programmatic variables from implementer surveys and integration of geospatial and temporal data based on differentiated recipient location. The odds of …
Timing Of Antiretroviral Therapy And Systemic Inflammation In Sub-Saharan Africa: Results From The Meta Longitudinal Cohort Study, Mark J. Siedner, Bosco M. Bwana, Stephen Asiimwe, Gideon Amanyire, Nicholas Musinguzi, Jose R. Castillo-Mancilla, Russell P. Tracy, Ingrid T. Katz, David Bangsberg, Multiple Additional Authors
Timing Of Antiretroviral Therapy And Systemic Inflammation In Sub-Saharan Africa: Results From The Meta Longitudinal Cohort Study, Mark J. Siedner, Bosco M. Bwana, Stephen Asiimwe, Gideon Amanyire, Nicholas Musinguzi, Jose R. Castillo-Mancilla, Russell P. Tracy, Ingrid T. Katz, David Bangsberg, Multiple Additional Authors
OHSU-PSU School of Public Health Faculty Publications and Presentations
Chronic inflammation predicts complications in persons with human immunodeficiency virus infection. We compared D-dimer, soluble CD14, and interleukin 6 levels before and 12 months after antiretroviral therapy (ART) initiation, among individuals starting ART during earlier-stage (CD4 T-cell count >350/μL) or late-stage disease (CD4 T-cell count <200/ μL). Female sex, older age, viral load, and late-stage disease were associated with pre-ART biomarkers (n = 661; P < .05). However, there were no differences in biomarkers by disease stage after 12 months of ART (n = 438; P > .05), owing to loss from observation and greater declines in biomarkers in latestage initiators (P < .001). Earlier initiation of ART is associated with decreased inflammation, but levels seem to converge between earlier and later initiators surviving to 12 months.
Shared Medical Appointments And Patient-Centered Experience: A Mixed-Methods Systematic Review, Kim H. Wadsworth, Trevor G. Archibald, Allison E. Payne, Anita K. Cleary, Byron L. Haney, Adam S. Hoverman
Shared Medical Appointments And Patient-Centered Experience: A Mixed-Methods Systematic Review, Kim H. Wadsworth, Trevor G. Archibald, Allison E. Payne, Anita K. Cleary, Byron L. Haney, Adam S. Hoverman
OHSU-PSU School of Public Health Faculty Publications and Presentations
Background: Shared medical appointments (SMAs), or group visits, are a healthcare delivery method with the potential to improve chronic disease management and preventive care. In this review, we sought to better understand opportunities, barriers, and limitations to SMAs based on patient experience in the primary care context.
Methods: An experienced biomedical librarian conducted literature searches of PubMed, Cochrane Library, PsycINFO, CINAHL, Web of Science, ClinicalTrials.gov, and SSRN for peer-reviewed publications published 1997 or after. We searched grey literature, nonempirical reports, social science publications, and citations from published systematic reviews. The search yielded 1359 papers, including qualitative, quantitative, …
Seasonal Patterns In Risk Factors For Taenia Solium Transmission: A Gps Tracking Study Of Pigs And Open Human Defecation In Northern Peru, Ian W. Pray, Claudio Muro, Ricardo Gamboa, Percy Vilchez, Wayne Wakeland, William Pan, William E. Lambert, Multiple Additional Authors
Seasonal Patterns In Risk Factors For Taenia Solium Transmission: A Gps Tracking Study Of Pigs And Open Human Defecation In Northern Peru, Ian W. Pray, Claudio Muro, Ricardo Gamboa, Percy Vilchez, Wayne Wakeland, William Pan, William E. Lambert, Multiple Additional Authors
OHSU-PSU School of Public Health Faculty Publications and Presentations
Background: Taenia solium (cysticercosis) is a parasitic cestode that is endemic in rural populations where open defecation is common and free-roaming pigs have access to human feces. The purpose of this study was to examine the roaming patterns of free-range pigs, and identify areas where T. solium transmission could occur via contact with human feces. We did this by using GPS trackers to log the movement of 108 pigs in three villages of northern Peru. Pigs were tracked for approximately six days each and tracking was repeated in the rainy and dry seasons. Maps of pig ranges were analyzed for …
Internet Addiction, Smartphone Addiction, And Hikikomori Trait In Japanese Young Adult: Social Isolation And Social Network, Masaru Tateno, Alan R. Teo, Wataru Ukai, Junichiro Kanazawa, Ryoko Katsuki, Hiroaki Kubo, Takahiro A. Kato
Internet Addiction, Smartphone Addiction, And Hikikomori Trait In Japanese Young Adult: Social Isolation And Social Network, Masaru Tateno, Alan R. Teo, Wataru Ukai, Junichiro Kanazawa, Ryoko Katsuki, Hiroaki Kubo, Takahiro A. Kato
OHSU-PSU School of Public Health Faculty Publications and Presentations
Background: As the number of internet users increases, problems related to internet overuse are becoming more and more serious. Adolescents and youth may be particularly attracted to and preoccupied with various online activities. In this study, we investigated the relationship of internet addiction, smartphone addiction, and the risk of hikikomori, severe social withdrawal, in Japanese young adult.
Methods: The subjects were 478 college/university students in Japan. They were requested to complete the study questionnaire, which consisted of questions about demographics, internet use, the Internet Addiction Test (IAT), the Smartphone Addiction Scale (SAS)–Short Version (SV), the 25-item Hikikomori Questionnaire …
Exploring The Extent Of The Hikikomori Phenomenon On Twitter: Mixed Methods Study Of Western Language Tweets, Pereira-Sanchez, Miguel Angel Alvarez-Mon, Angel Asunsolo Del Barco, Melchor Alvarez-Mon, Alan R. Teo
Exploring The Extent Of The Hikikomori Phenomenon On Twitter: Mixed Methods Study Of Western Language Tweets, Pereira-Sanchez, Miguel Angel Alvarez-Mon, Angel Asunsolo Del Barco, Melchor Alvarez-Mon, Alan R. Teo
OHSU-PSU School of Public Health Faculty Publications and Presentations
Background: Hikikomori is a severe form of social withdrawal, originally described in Japan but recently reported in other countries. Debate exists as to what extent hikikomori is viewed as a problem outside of the Japanese context. Objective: We aimed to explore perceptions about hikikomori outside Japan by analyzing Western language content from the popular social media platform, Twitter. Methods: We conducted a mixed methods analysis of all publicly available tweets using the hashtag #hikikomori between February 1 and August 16, 2018, in 5 Western languages (Catalan, English, French, Italian, and Spanish). Tweets were first classified as to whether they described …
Use Of Single Irbs For Multi-Site Studies: A Case Report And Commentary From A National Drug Abuse Treatment Clinical Trials Network Study, Ceilidh Nichols, Lynn E. Kunkel, Robin Baker, Eve Jelstrom, Megan Addis, Kim Hoffman, Dennis Mccarty, P. Todd Korthuis
Use Of Single Irbs For Multi-Site Studies: A Case Report And Commentary From A National Drug Abuse Treatment Clinical Trials Network Study, Ceilidh Nichols, Lynn E. Kunkel, Robin Baker, Eve Jelstrom, Megan Addis, Kim Hoffman, Dennis Mccarty, P. Todd Korthuis
OHSU-PSU School of Public Health Faculty Publications and Presentations
Recent NIH policy stipulates that multi-site studies must use a single or IRB (Institutional Review Board) in order to streamline the review process while maintaining standards for human subjects protection. The Western States Node of the Clinical Trials Network (CTN) used a single IRB for protocol CTN-0067, a clinical trial testing the use of an opioid antagonist (extended-release naltrexone) versus opioid agonists (buprenorphine or methadone) for opioid use disorders among individuals living with HIV. This case study discusses the processes and challenges associated with use of a single IRB. These lessons are also informed by other single IRB experiences within …
Impacts Of An Opioid Overdose Prevention Intervention Delivered Subsequent To Acute Care, Caleb J. Banta-Green, Phillip O. Coffin, Joseph O. Merrill, Jeanne M. Sears, Chris Dunn, Norbert D. Yanez, Multiple Additional Authors
Impacts Of An Opioid Overdose Prevention Intervention Delivered Subsequent To Acute Care, Caleb J. Banta-Green, Phillip O. Coffin, Joseph O. Merrill, Jeanne M. Sears, Chris Dunn, Norbert D. Yanez, Multiple Additional Authors
OHSU-PSU School of Public Health Faculty Publications and Presentations
Background Opioid overdose is a major and increasing cause of injury and death. There is an urgent need for interventions to reduce overdose events among high-risk persons.
Methods Adults at elevated risk for opioid overdose involving heroin or pharmaceutical opioids who had been cared for in an emergency department (ED) were randomised to overdose education combined with a brief behavioural intervention and take-home naloxone or usual care. Outcomes included: (1) time to first opioid overdose-related event resulting in medical attention or death using competing risks survival analysis; and (2) ED visit and hospitalisation rates, using negative binomial regression and adjusting …