Medicine and Health Sciences Commons^™

Layout And Flow Of Dermatology Clinics: Principles From Operations Management., Jordan V. Wang

Department of Dermatology and Cutaneous Biology Faculty Papers

Dermatology is a medical specialty that experiences high patient demand and long patient wait times. Dermatology clinics should look for ways to improve efficiency through the incorporation of principles from operations management. Addressing the layout and flow of a clinic can lead to operational efficiency. An ideal layout may lead to increased patient volume, satisfaction, and retention.

April 2018, Randy Curry, Cindy Brooks

RURAL ROCKS

Rural Rocks, the Rural Health Network newsletter by the SWOSU College of Pharmacy

Optimizing Visiting Clerkships In Dermatology: A Dual Perspective Approach., Jordan V. Wang, Kathleen P. Mcguinn, Matthew Keller

Department of Dermatology and Cutaneous Biology Faculty Papers

Matching into a dermatology residency program has become increasingly more challenging for medical students. As students continue to explore various methods to help them standout to programs, recent medical literature has continued to show evidence of the important role that visiting clerkships play. Visiting clerkships offer several benefits to both students and programs. In order to optimize visiting clerkships, the perspectives of both students and programs are each examined with recommendations provided to help maximize its benefits.

Within Season Hematological Changes In College Athletes With Sickle Cell Trait, Michael E. Owens

LSU Master's Theses

ABSTRACT

PURPOSE: To explore the hematological differences in African-American athletes with sickle cell trait (SCT) and healthy controls (CON) before preseason camp and the changes that occur after a full season. METHODS: Sixteen (n=8 SCT; n=8 position matched, CON) NCAA Division 1 athletes (12 football, 2 each women’s soccer and volleyball) had blood drawn before preseason camp, after and at the end of the season, and analyzed for Hb electrophoresis (Hb-A, Hb-A2, Hb-S, and Hb-F), complete blood count with differential, chemistry panel 26, and prothrombin time, activity and international normalized ratio (INR). RESULTS: Baseline total Hb was …

The Predictors Of Juvenile Recidivism: Testimonies Of Adult Students 18 Years And Older Exiting From Alternative Education, La Toshia Palmer

Dissertations

Purpose: The purpose of this descriptive, qualitative study was to identify and describe the importance of the predictors of juvenile recidivism and the effectiveness of efforts to prevent/avoid juvenile recidivism as perceived by previously detained, arrested, convicted, and/or incarcerated adult students 18 years of age and older exiting from alternative education in Northern California. A second purpose was to explore the types of support provided by alternative schools and the perceived importance of the support to avoid recidivism according to adult students 18 years of age and older exiting from alternative education.

Methodology: This qualitative, descriptive research design identified …

Exploring An Expressive Arts Protocol In The Recovery Of Substance Use Disorders In An Intensive Outpatient Program, Joie De Bostock

Expressive Therapies Capstone Theses

Approaches in treatment of chemical dependency have focused primarily on psychoeducation in group therapy, with limited research involving expressive therapies. Literature has shown benefit in the use of expressive arts for those in mental health treatment, with a limited amount of research on expressive arts in the treatment of substance abuse disorders (SUDs), though it is uncommon for individuals in chemical dependency treatment to receive therapy in any expressive modality. This may be due to several factors, such as resources for supplies or limitations in funding, however, an outlet of expression could benefit this population and contribute to successful recovery …

Importance Of Coverage And Quality For Impact Of Nutrition Interventions Delivered Through An Existing Health Programme In Bangladesh, Phuong Hong Nguyen, Edward A. Frongillo Jr., Tina Sanghvi, Sunny S. Kim, Silvia Alayon, Lan Mai Tran, Zeba Mahmud, Bachera Aktar, Purnima Menon

Faculty Publications

Understanding implementation of interventions is critical to illuminate if, how, and why the interventions achieve impact. Alive & Thrive integrated a nutrition intervention into an existing maternal, neonatal, and child health (MNCH) programme in Bangladesh, documenting improvements in women's micronutrient supplement intake and dietary diversity. Here, we examined how well the nutrition intervention was implemented and which elements of implementation explained intervention impact. Survey data were collected in 2015 and 2016 from frontline health workers (FLW) and households in areas randomized to nutrition‐focused MNCH (intensified interpersonal counselling, community mobilization, distribution of free micronutrient supplements, and weight‐gain monitoring) or standard MNCH …

No Risk Reduction For Plasmodium Vivax Malaria In Sickle Cell Disease, Bushra Moiz, Ayesha Majeed Memon

Department of Pathology and Laboratory Medicine

Hemoglobin S is known to protect against uncomplicated Plasmodium falciparum malaria. However, there is paucity of the literature regarding interaction of HbS and other malaria species. Usually, P. vivax malaria is a relapsing condition, and without radical cure with primaquine, recurrence may be observed even with hemoglobin S.

Maternal Coxsackievirus B Induced Dysregulation Of Sumoylation Processes As A Potential Cause Of Hypoplastic Left Heart Syndrome, Bailey Kemp, Sarah Severson

Undergraduate Research Symposium 2018

Hypoplastic Left Heart Syndrome (HLHS) is a life-threatening congenital heart defect with unknown etiology. Here we hypothesize that HLHS has etiologic roots in maternal asymptomatic coxsackievirus B infection. Coxsackievirus has been demonstrated to disrupt normal distribution of small ubiquitin-like modifiers (SUMO) in the cell. The vital cardiac transcription factor, Nkx2-5, has been shown to be dependent on SUMOylation for proper function. Specifically, co-localization of SUMO and Nkx2.5 has been identified, as well as decreased SUMOylation associated with Nkx2-5 mutants. As Nxk2-5 is essential for fetal heart development and mutations in the gene for this vital transcription factor have been linked …

Parenting Practices And Disordered Eating Behaviors In Adolescents, Rebekah Johnson

Student Works

Background/Purpose: Eating disorders are a common chronic condition among adolescents. Some parenting styles have been associated with adolescent disordered eating behaviors (DEB), which can lead to eating disorders and a variety of other psychological and physical complaints. Healthcare practitioners and parents need to identify these DEB early and intervene in hopes of preventing the sequela of other health problems. The purpose of this article is to review current research on the association between parenting styles or practices and DEB as well as associated psychological symptoms in adolescents.

Methods: CINAHL, Academic Search Premier, MEDLINE, and PsycINFO databases were searched for English-language …

Evaluating The Aryl Hydrocarbon Receptor As A Target For Pharmacologic Activity Of Repurposed Drugs, Teofilo Borunda Duque

Pharmaceutical Sciences ETDs

The discovery of new pharmacologic targets is important for the advancement of pharmacotherapy and identification of new indications for current drugs. The aryl hydrocarbon receptor (AHR) is a physiologic sensor of both chemical environmental pollutants and ligands of natural origin. Given the broad spectrum of ligands that activate the AHR and its relationship with toxicology, the AHR is not thought to be a traditional target for pharmacotherapy. However, multiple studies have shown potential for the AHR as a novel pharmacologic target Therefore, identifying less toxic agents that modulate the AHR may elucidate mechanisms for pharmacological targeting of the AHR. The …

Sk Channel Modulators As Drug Candidates And Pharmacological Tools, Razan Orfali

Pharmaceutical Sciences (MS) Theses

The small- and intermediate-conductance Ca2+ activated K + (SK/IK) channels play a fundamental role in the regulation of neurons in the central nervous system. In animal models, SK/IK channel positive modulators have been shown to be effective in reducing the symptoms of neurological diseases such as ataxia. Ataxia is a lethal neurological rare disease characterized by lack of balance and incoordination of muscle movements, often as a result of cerebellar or spinocerebellar neurodegeneration. SK/IK channel modulators have been developed over the past few decades. Currently available modulators are often weak in potency. Lack of knowledge about the binding site for …

Risk Thresholds For Alcohol Consumption: Combined Analysis Of Individual-Participant Data For 599 912 Current Drinkers In 83 Prospective Studies, Angela Wood, Carlos J. Crespo, Emerging Risk Factors Collaboration/Epic-Cvd/Uk Biobank Alcohol Study Group

OHSU-PSU School of Public Health Faculty Publications and Presentations

Background: Low-risk limits recommended for alcohol consumption vary substantially across different national guidelines. To define thresholds associated with lowest risk for all-cause mortality and cardiovascular disease, we studied individual-participant data from 599 912 current drinkers without previous cardiovascular disease.

Methods: We did a combined analysis of individual-participant data from three large-scale data sources in 19 high-income countries (the Emerging Risk Factors Collaboration, EPIC-CVD, and the UK Biobank). We characterised dose–response associations and calculated hazard ratios (HRs) per 100 g per week of alcohol (12·5 units per week) across 83 prospective studies, adjusting at least for study or centre, …

Extending The Phenotypic Spectrum Of Sengers Syndrome: Congenital Lactic Acidosis With Synthetic Liver Dysfunction., David B Beck, Kristina Cusmano-Ozog, Nickie Andescavage, Eyby Leon

Pathology Faculty Publications

Sengers syndrome is a rare autosomal recessive mitochondrial disease characterized by lactic acidosis, hypertrophic cardiomyopathy and bilateral cataracts. We present here a case of neonatal demise, within the first day of life, who initially presented with severe lactic acidosis, with evidence of both chorioamnionitis and cardiogenic shock. Initial metabolic labs demonstrated a severe lactic acidosis prompting genetic testing which revealed a homozygous pathogenic variant for Sengers syndrome in

Loss Of Inter-Cellular Cooperation By Complete Epithelial-Mesenchymal Transition Supports Favorable Outcomes In Basal Breast Cancer Patients., Anne Grosse-Wilde, Rolf E Kuestner, Stephanie M Skelton, Ellie Macintosh, Aymeric Fouquier D'Hérouël, Gökhan Ertaylan, Antonio Del Sol, Alexander Skupin, Sui Huang

Articles, Abstracts, and Reports

According to the sequential metastasis model, aggressive mesenchymal (M) metastasis-initiating cells (MICs) are generated by an epithelial-mesenchymal transition (EMT) which eventually is reversed by a mesenchymal-epithelial transition (MET) and outgrowth of life-threatening epithelial (E) macrometastases. Paradoxically, in breast cancer M signatures are linked with more favorable outcomes than E signatures, and M cells are often dispensable for metastasis in mouse models. Here we present evidence at the cellular and patient level for the cooperation metastasis model, according to which E cells are MICs, while M cells merely support E cell persistence through cooperation. We tracked the fates of co-cultured E …

Perceptions Of A Cardiovascular Stress Management Intervention In University Employees, Janki Patel

Research Horizons Day Posters

No abstract provided.

Chlorine Stain And The Oral Cavity, Alexandra B. Moore

Dental Hygiene ETDs

Swimming is known worldwide as one of the healthiest, low-impact forms of exercise and for the subsequent promotion of a strong body, heart, and mind. However, many swimmers and non-swimmers do not realize that swimming in a pool can have a negative effect on the oral cavity. Several studies have suggested that pool chlorination is responsible for dental erosion, calculus formation, and stain in competitive and recreational swimmers, and this phenomenon is known as ‘swimmer’s mouth.’ A pilot experimental research study was conducted that evaluated the prevalence of chlorine stain in the oral cavity of twenty-one female swimmers from the …

Reducing Communication Errors In The Clinical Setting By Implementing A Standardized Communication Tool: Isbarr, Nur 307, Fall 2017

Research Horizons Day Posters

No abstract provided.

Differential Effects Of Linkers On The Activity Of Amphiphilic Tobramycin Antifungals, Marina Y. Fosso, Sanjib K. Shrestha, Nishad Thamban Chandrika, Emily K. Dennis, Keith D. Green, Sylvie Garneau-Tsodikova

Pharmaceutical Sciences Faculty Publications

As the threat associated with fungal infections continues to rise and the availability of antifungal drugs remains a concern, it becomes obvious that the need to bolster the antifungal armamentarium is urgent. Building from our previous findings of tobramycin (TOB) derivatives with antifungal activity, we further investigate the effects of various linkers on the biological activity of these aminoglycosides. Herein, we analyze how thioether, sulfone, triazole, amide, and ether functionalities affect the antifungal activity of alkylated TOB derivatives against 22 Candida, Cryptococcus, and Aspergillus species. We also evaluate their impact on the hemolysis of murine erythrocytes and the …

Health-Related Fitness Differences Amongst Allied And Non-Allied Undergraduate Health Majors, Grant Ragan, Amy Shepherd, Narges Shirazi, Kaitlin Smith

Research Horizons Day Posters

No abstract provided.

Can Prescribed Fire Reduce Tick Parasitism Of Birds?, Leslie A. Sterling, Kim Medley, Katie Westby, Solný Adalsteinsson

Undergraduate Research Symposium Posters

Tick-borne diseases spread through enzootic transmission cycles that often involve ticks parasitizing bird hosts. Some avian species are competent reservoirs, amplifying the pathogens that cause tick-borne illnesses in humans. Prescribed burns in forests have the potential to reduce tick-borne disease risk if they limit interactions between ticks and infectious wildlife hosts. Although prescribed burns are increasingly being used for a variety of habitat management purposes, little is known about how they affect tick-host interactions. We hypothesize that if prescribed fires reduce tick abundance, then birds in burned forest plots will host fewer ticks than birds in unburned forest plots. Experimental …

A Model For Rigorously Applying The Exploration, Preparation, Implementation, Sustainment (Epis) Framework In The Design And Measurement Of A Large Scale Collaborative Multi-Site Study, Jennifer E. Becan, John P. Bartkowski, Danica K. Knight, Tisha R. A. Wiley, Ralph Diclemente, Lori Ducharme, Wayne N. Welsh, Diana Bowser, Kathryn Mccollister, Matthew Hiller, Anne C. Spaulding, Patrick M. Flynn, Andrea Swartzendruber, Megan F. Dickson, Jacqueline Horan Fisher, Gregory A. Aarons

Center on Drug and Alcohol Research Faculty Publications

Background

This paper describes the means by which a United States National Institute on Drug Abuse (NIDA)-funded cooperative, Juvenile Justice-Translational Research on Interventions for Adolescents in the Legal System (JJ-TRIALS), utilized an established implementation science framework in conducting a multi-site, multi-research center implementation intervention initiative. The initiative aimed to bolster the ability of juvenile justice agencies to address unmet client needs related to substance use while enhancing inter-organizational relationships between juvenile justice and local behavioral health partners.

Methods

The EPIS (Exploration, Preparation, Implementation, Sustainment) framework was selected and utilized as the guiding model from inception through project completion; including the …

Home Health Nurse Decision-Making Regarding Visit Intensity Planning For Newly Admitted Patients: A Qualitative Descriptive Study, Elliane Irani

Faculty Scholarship

Despite patients referred to home health having diverse and complex needs, it is unknown how nurses develop personalized visit plans. In this qualitative descriptive study, we interviewed 26 nurses from three agencies about their decision-making process to determine visit intensity and analyzed data using directed content analysis. Following a multifactorial assessment of the patient, nurses relied on their experience and their agency’s protocols to develop the personalized visit plan. They revised the plan based on changes in the patient’s clinical condition, engagement, and caregiver availability. Findings suggest strategies to improve visit planning and positively influence outcomes of home health patients.

An Inpatient Patient Safety Curriculum For Pediatric Residents., John Szymusiak, Michael D Fox, Catherine Polak, Kwonho Jeong, Doris Rubio, Stephanie Dewar, Andrew Urbach, Alda Maria Gonzaga

Department of Pediatrics Faculty Papers

Introduction: Patient safety is recognized as an important part of pediatric resident education. There is a lack of published safety curricula targeting pediatric residents. A local needs assessment showed that while residents felt safety was an important part of their current and future jobs, they did not feel prepared to apply safety principles to their future careers or participate in a root cause analysis (RCA).

Methods: This curriculum was delivered to senior-level pediatric and multiple-board residents during five monthly, hour-long, multidisciplinary sessions. Sessions covered systems-based thinking, terminology, the second victim phenomenon, RCA, and medication errors, while providing feedback on recent …

Advanced Disease Management In Home Healthcare: Palliative Integration, Missy Stober

Graduate Theses, Dissertations, and Capstones

Advanced Disease Management in Home Healthcare: Palliative Care Integration

Abstract

With home health caring for patients with serious illnesses and advancing disease states, palliative care in a community setting like the home, can provide many benefits. This population currently has a gap in the healthcare continuum at the point of advancing disease state to end of life care. Recently, new payment models based around clinical outcomes, including hospitalization scores and quality indicators, has caused home health to explore different ways to deliver quality and effective care, especially for those with the highest risk of hospitalization. A literature review was conducted …

World Health Organization Decision Making Tool For Family Planning- Can We Increase Iud Use?, Kim Anna

Graduate Theses, Dissertations, and Capstones

Background and Purpose: Worldwide unintended pregnancy rates are reported at 40% of all pregnancies. The United States has an unintended pregnancy rate of 45%. Contraception is safe and available for most women. Many providers lack evidence-based tools and current information in assisting clients to choose a highly effective contraceptive method. Intrauterine devices (IUD) and implants are highly effective contraception. The American College of Obstetricians and Gynecologists (ACOG) and the American Academy of Pediatrics (AAP) recommend IUDs and implants as first tier contraception for most sexually active females.

Methods: Implementation of the World Health Organization Decision-Making Tool (WHO DMT) for contraceptive …

Nora Guthrie: We’Re All ‘Hoping Machines’ In The Fight Against Huntington's Disease, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.

Perceptions And Use Of Nonnutritive Sweeteners Among College Students Based Upon Athletic Status, Gender, And Academic Major, Madison B. Heydinger

Honors College Theses

Nonnutritive sweeteners, which include sucralose, aspartame, saccharin, and stevia may positively impact health of individuals by helping to reduce Caloric and added sugar intake. Athletes may consider these factors when attempting to improve performance and, as such, may benefit from their use. However, no one has examined sources of nutrition knowledge and perceptions as well as use of nonnutritive sweeteners in college students based upon athletic status, gender, and whether students are studying a health or non-health related major. The objective of this study was to compare college students’ sources of nutrition knowledge to their perceptions and consumption of nonnutritive …

College Of Public Health News, Georgia Southern University

College of Public Health: News & Publications

• Georgia Southern Examines Water Quality and Perception of Risk
• Georgia Southern Wins Best Presentation Award

Environmental Health News, Georgia Southern University

Biostatistics, Epidemiology & Environmental Health Sciences: News & Publications (2011-2018)

• Georgia Southern Examines Water Quality and Perception of Risk