Medicine and Health Sciences Commons^™

Individualized Music Improves Social Interaction Of Women, But Not Men, With Dementia, Emily Farrer, Diana Hilycord

Butler Journal of Undergraduate Research

Dementia is tragic both for patients with the disease and for their family members. As this neurodegenerative disorder progresses, cognitive functions deteriorate, agitation and aggression increase, and mood worsens (McDermott, Orrell, et al., 2014; Spiro, 2010; Vasionyté & Madison, 2013). Non-pharmacological approaches, such as active music therapy or passive music listening, can be effective in reducing these symptoms. However, no past studies have examined how music listening affects the social interactions of patients with dementia. As such, this study examined whether nursing home residents with dementia are more engaged and interactive if they listen to individually selected music for 15 …

Allopathic Medicine’S Influence On Indigenous Peoples In The Kumaon Region Of India, Eliana M. Blum

Butler Journal of Undergraduate Research

This paper focuses on the use of western medicine in the Kumaon region of Uttarakhand, India. The goal of this research is to understand which healing practices are preferable in rural villages. Semi-structured interviews were conducted with 53 participants, including two spiritual healers, two doctors, and one pharmacist. Results indicate that allopathic medicine, otherwise known as modern medicine or western medicine, has become the go-to remedy for even the most remote people in India. Nearly all participants use allopathic medicine, but less than half of the participants experiment with other forms of healing, such as Ayurveda, homeopathy, meditation, and yoga. …

A Community's Collective Courage: A Local Food Cooperative's Impact On Food Insecurity, Community And Economic Development, And Local Food Systems, Tabitha C. Barbour

Butler Journal of Undergraduate Research

According to the USDA’s “Food Security Status of U.S. Households” in 2014, 48.1 million people live in food insecure households. In Indiana, more than 1 million people suffer from food insecurity with rates as high as 19.2% of Marion County’s population according to the Map the Meal Gap 2014 report. The Community Controlled Food Initiative (CCFI) is a local food cooperative operated by the Kheprw Institute and neighborhood residents in the Mid-North Indianapolis Community. The cooperative formed to address food insecurity in August 2015 in response to the closing on the local Double 8 Foods grocery stores. CCFI hosts a …

Volume 4 Table Of Contents

Butler Journal of Undergraduate Research

No abstract provided.

In Place: April 16, 2018, Place

PLACE Historical Documents

In PLACE is a newsletter designed to keep the Linfield College community apprised of information related to PLACE activities, as well as ways to bring the program into classes. Included in this issue:

• Spotlight On: The Politicization of Science, P. II
• Upcoming Events
• PLACE in the News

Synergic Trial (Synchronizing Exercises, Remedies In Gait And Cognition) A Multi-Centre Randomized Controlled Double Blind Trial To Improve Gait And Cognition In Mild Cognitive Impairment, Manuel Montero-Odasso, Quincy J. Almeida, Amer M. Burhan, Richard Camicioli, Julien Doyon, Sarah Fraser, Karen Li, Teresa Liu-Ambrose, Laura Middleton, Susan Muir-Hunter, William Mcilroy, José A. Morais, Frederico Pieruccini-Faria, Kevin Shoemaker, Mark Speechley, Akshya Vasudev, G. Y. Zou, Nicolas Berryman, Maxime Lussier, Leanne Vanderhaeghe, Louis Bherer

Bone and Joint Institute

© 2018 The Author(s). Background: Physical exercise, cognitive training, and vitamin D are low cost interventions that have the potential to enhance cognitive function and mobility in older adults, especially in pre-dementia states such as Mild Cognitive Impairment (MCI). Aerobic and progressive resistance exercises have benefits to cognitive performance, though evidence is somewhat inconsistent. We postulate that combined aerobic exercise (AE) and progressive resistance training (RT) (combined exercise) will have a better effect on cognition than a balance and toning control (BAT) intervention in older adults with MCI. We also expect that adding cognitive training and vitamin D supplementation to …

Surgery And Conservative Treatment Of The Acl-Mcl Injured Knee, Mason Mcmanimon-Myers

Undergraduate Research Celebration 2018

There is a clinical need to evaluate the effectiveness of nonoperative versus operative treatment of the anterior cruciate ligament (ACL)-medial collateral ligament (MCL) combined knee injury. The incidence of these injuries is frequent in athletic populations and requires the best treatment for optimal patient outcomes and function in day-to-day life as well as athletics. The appraisal focuses on whether or not to pair ACL reconstruction with MCL reconstruction or ACL reconstruction with MCL bracing. Focused Clinical Question: What is the effect on patients with a combined ACL-MCL injury of the knee with conservative treatment compared to surgery on patient reported …

Ada News - 04/16/2018, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Spanning External Fixation For The Treatment Of Open Joint Injuries In Pediatric Burn Patients., Kelly Carmichael, Daniel Torres, Carlos J Jimenez, Matthew C Comley, Ernest B Evans

Department of Surgery

In this article, we report a case series on spanning external fixation for the treatment of open joint burn injuries in a pediatric population. We reviewed the case logs of all orthopedic surgeons from 2000 to 2010 at a burn hospital to identify pediatric patients with open joints secondary to burn injuries. Nine patients who sustained open joint injuries after a burn and treated with a spanning external fixator (SEF) were identified. Characteristics of the burns included: five elbow, four knee; seven flame, two electrical; average total body surface area affected 49.4% (range 25%-79%); substantial third-degree burn in all patients. …

The Importance Of Clinical Documentation Improvement, Amanda Shanty Baksh

Applied Research Projects

The world of technology in the twenty first century is forever expanding. In the healthcare field, patient data has transformed from paper charts into electronic health records. Electronic health records allow for organized patient information however, an enormous amount of information becomes available. Sometimes the massive amount of information is not always needed but important detail the medical chart is looked for by insurance companies for reimbursement. There is a special department in hospitals called the Clinical Documentation Improvement specialists who are made up of experienced medical coders, registered nurses, mid-level practitioners such as nurse practitioner’s s or physician’s assistants …

Transcranial Direct Current Stimulation (Tdcs) Improves Performance On Spelling And Word Detection Tasks, J. Kevin Wilson

Psychology ETDs

Deficits in written language involving spelling can have negative effects on a person’s education and occupation. Conventional spelling therapy is a time consuming and cost-prohibitive option, if even available, highlighting the need for improved methods for remediation. One possible way to address this need may be through the use of transcranial direct current stimulation (tDCS). This study sought to examine the effects of tDCS on performance during spelling, word detection, and facial recognition tasks. Active or sham tDCS was randomly assigned to typically functioning adults. The anode electrode was placed over Broca’s area (F7 in the 10/20 EEG system) and …

Kshv Induces Immunoglobulin Rearrangements In Mature B Lymphocytes, Jennifer Totonchy, Jessica M. Osborn, Amy Chadburn, Ramina Nabiee, Lissenya Argueta, Geoffrey Mikita, Ethel Cesarman

Pharmacy Faculty Articles and Research

Kaposi sarcoma herpesvirus (KSHV/HHV-8) is a B cell tropic human pathogen, which is present in vivo in monotypic immunoglobulin λ (Igλ) light chain but polyclonal B cells. In the current study, we use cell sorting to infect specific B cell lineages from human tonsil specimens in order to examine the immunophenotypic alterations associated with KSHV infection. We describe IL-6 dependent maturation of naïve B lymphocytes in response to KSHV infection and determine that the Igλ monotypic bias of KSHV infection in vivo is due to viral induction of BCR revision. Infection of immunoglobulin κ (Igκ) naïve B cells induces expression …

N-Terminal Pro-B-Type Natriuretic Peptide And Microsize Myocardial Infarction Risk In The Reasons For Geographic And Racial Differences In Stroke Study, Madeline R. Sterling, Raegan W. Durant, Joanna Bryan, Emily B. Levitan, Todd M. Brown, Yulia Khodneva, Stephen P. Glasser, Joshua S. Richman, George Howard, Mary Cushman, Monika M. Safford

Internal Medicine Faculty Publications

Background: N-terminal pro B-type peptide (NT-proBNP) has been associated with risk of myocardial infarction (MI), but less is known about the relationship between NT-proBNP and very small non ST-elevation MI, also known as microsize MI. These events are now routinely detectable with modern troponin assays and are emerging as a large proportion of all MI. Here, we sought to compare the association of NT-proBNP with risk of incident typical MI and microsize MI in the REasons for Geographic and Racial Differences in Stroke (REGARDS) Study.

Methods: The REGARDS Study is a national cohort of 30,239 US community-dwelling black and white …

How To Measure Success, Deborah Eldredge, Mary Waldo

Books, Presentations, Posters, Etc.

No abstract provided.

Primary Intrahepatic Mesotheliomas: A Case Presentation And Literature Review, Hishaam Ismael, Steven Cox

School of Medicine Faculty Publications and Presentations

Introduction Primary Intrahepatic mesotheliomas are malignant tumors arising from the mesothelial cell layer covering Glisson's capsule of the liver. They are exceedingly rare with only fourteen cases reported in the literature. They have nonspecific signs and symptoms and need a high index of suspicion and an extensive workup prior to surgery. Surgery remains the mainstay of treatment. Presentation of case 48 year old male presented with a 3 months history of abdominal pain, productive cough, anemia and weight loss. He had no history of asbestos exposure. A computed tomography scan and magnetic resonance study demonstrated a heterogeneous subscapular mass within …

Credibility, Replicability, And Reproducibility In Simulation For Biomedicine And Clinical Applications In Neuroscience., Lealem Mulugeta, Andrew Drach, Ahmet Erdemir, C A Hunt, Marc Horner, Joy P. Ku, Jerry G Myers, Rajanikanth Vadigepalli, William W. Lytton

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Modeling and simulation in computational neuroscience is currently a research enterprise to better understand neural systems. It is not yet directly applicable to the problems of patients with brain disease. To be used for clinical applications, there must not only be considerable progress in the field but also a concerted effort to use best practices in order to demonstrate model credibility to regulatory bodies, to clinics and hospitals, to doctors, and to patients. In doing this for neuroscience, we can learn lessons from long-standing practices in other areas of simulation (aircraft, computer chips), from software engineering, and from other biomedical …

Recovering Parasites From Mummies And Coprolites: An Epidemiological Approach, Morgana Camacho, Adauto Araújo, Johnica J. Morrow, Jane E. Buikstra, Karl Reinhard

Karl Reinhard Publications

In the field of archaeological parasitology, researchers have long documented the distribution of parasites in archaeological time and space through the analysis of coprolites and human remains. This area of research defined the origin and migration of parasites through presence/absence studies. By the end of the 20th century, the field of pathoecology had emerged as researchers developed an interest in the ancient ecology of parasite transmission. Supporting studies were conducted to establish the relationships between parasites and humans, including cultural, subsistence, and ecological reconstructions. Parasite prevalence data were collected to infer the impact of parasitism on human health. In the …

Midwives’ Perceptions On Using A Fetoscope And Doppler For Fetal Heart Rate Assessments During Labor: A Qualitative Study In Rural Tanzania, Paschal Francis Mdoe, Hege Langli Ersdal, Estomih Mduma, Robert Moshiro, Hussein Kidanto, Columba Mbekenga

School of Nursing & Midwifery, East Africa

Background: The Doppler is thought to be more comfortable and effective compared to the fetoscope for assessing the fetal heart rate (FHR) during labor. However, in a rural Tanzanian hospital, midwives who had easy access to both devices mostly used fetoscope. This study explored midwives’ perception of factors influencing their preference for using either a Pinard fetoscope or a FreePlay wind-up Doppler for intermittent FHR monitoring.

Methods: Midwives who had worked for at least 6 months in the labor ward were recruited. Focus group discussion (FGD) was used to collect data. Five FGDs were conducted between December 2015 and February …

Week Of April 16, 2018, New York Medical College

InTouch

• Graduate Medical Education Programs Receive Continued Full Accreditation With Flying Colors
• NYMC Set to Commemorate Yom Hashoah On April 17
• SHSP Hosts Second Annual Alumni Networking Event
• Students Take a Break at Springtime SOM Alumni Association Mixer

Inventing Pollution : Coal, Smoke, And Culture In Britain Since 1800, Peter Thorsheim

Ohio University Press Open Access Books

Going as far back as the thirteenth century, Britons mined and burned coal. Britain’s supremacy in the nineteenth century depended in large part on its vast deposits of coal, which powered industry, warmed homes, and cooked food. As coal consumption skyrocketed, the air in Britain’s cities and towns filled with ever-greater and denser clouds of smoke. Yet, for much of the nineteenth century, few people in Britain even considered coal smoke to be pollution.

Inventing Pollution examines the radically new understanding of pollution that emerged in the late nineteenth century, one that centered not on organic decay but on coal …

Life During The Biggest Loser: Experiences And Perspectives Of Non-Contestant Romantic Partners, Darren D. Moore, Clinton Cooper, Kai Zwierstra, Toiya Williams

The Qualitative Report

For this study, authors engaged in 9 semi-structured interviews with romantic partners of contestants who were involved with a weight loss intervention (The Biggest Loser), to gain insight into the phenomenon of weight loss within the context of couple relationships and reality television. Utilizing Basic Qualitative Description influenced by aspects of phenomenology, the authors explored the role of weight loss and the role that the specific intervention utilized, has played within the couple relationship. Building upon previous research (Moore, Cooper, Williams, & Zwierstra, 2017a) authors added the voice of the non-contestant partners to the discussion and explored experiences …

Targeting The Hsp90/Aha1 Complex For The Treatment Of Tauopathies, Lindsey Brooke Shelton

USF Tampa Graduate Theses and Dissertations

The microtubule associated protein, tau, is involved in regulating microtubule stability and axonal transport. When tau becomes hyperphosphorylated it can disassociate from the microtubules and start to aggregate. These tau aggregates are the hallmarks of many diseases known as tauopathies. The heat shock protein 90 kDa (Hsp90) chaperone network is highly involved in modulating client proteins, including tau. However, during aging and disease the Hsp90 chaperone network becomes highly imbalanced with some Hsp90/co-chaperone complexes increasing, while others are repressed. This imbalance in Hsp90/co-chaperone complexes could result in a worsening of tau pathology in Alzheimer’s disease.

Hsp90 inhibition has been of …

Exploring The Relationship Between Family Social Capital And Utilization Of Well Child Preventative Health Care Services, Kristi K. Westphaln

Dissertations

Background: Passage of the Affordable Health Care Act of 2010 increased insurance coverage for children, however possession of health care insurance doesn’t always equate to effective use of health care services. Misuse and underutilization of health care homes is associated with higher costs, fragmentation of health care, and poor health outcomes across the lifespan. Along with reliance upon the health care system, child health and well-being are dependent upon social factors such as interactions with caregivers and communities. Family social capital (FSC) addresses the interrelated nature of child health and family interaction while also promoting family cohesion as currency …

Incidence Of Dysphagia After Odontoid Screw Fixation Of Type Ii Odontoid Fracture In The Elderly., Rudy D Marciano, Brian Seaman, Saurabh Sharma, Teresa Wood, Chris Karas, Kailash Narayan

Surgery Articles

BACKGROUND: Although surgery may reduce mortality rates from type II odontoid fractures in the elderly population, post-operative dysphagia resulting from screw fixation remains a serious complication.

METHODS: We retrospectively performed a chart review of patients over 65 years of age who underwent odontoid screw placement for type II odontoid fractures (2009-2014) and sustained post-operative dysphagia. The severity of dysphagia was determined based on the requirements for modified diets, PEG tubes, and prolonged length of stay (LOS), while costs were based upon discharge disposition (e.g. home vs. rehabilitation facilities) and total hospital costs.

RESULTS: The incidence of postoperative dysphagia was 80%; …

Reversible Cerebral Vasoconstriction Disorder In A Patient With A Chief Complaint Of Headache., Simran Buttar, Anuja Trivedi, Dimitrios Papanagnou, Md

Department of Emergency Medicine Faculty Papers

As emergency medicine physicians, we have formulated an approach to managing patients with a chief complaint of headache that starts with considering the story the patient relays in the context of a wide differential. Here we will describe a case that presented to our emergency department in hopes to broaden your differential. Reversible cerebral vasoconstriction syndrome (RCVS), well described in the neurology literature, is characterized by severe headaches that may or may not be accompanied by neurological symptoms and is definitively diagnosed by diffuse constriction of cerebral arteries on cerebral angiogram. Here we present a case of a patient who …

Medical School Watercooler Newsletter - April 15, 2018, Lindsey Lyle

Watercooler Newsletter

This is the April 15, 2018 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents Include:

• Med School Café – Expert Advice for the Community
• Dr. William Broughton Presents at Southern Sleep Society Meeting
• USA Health Participates in National Walk at Lunch Day
• USA COM Opens New Multipurpose Room
• Autism Matters Conference Set for May 4

The Use Of Ace Inhibitors And Angiotensin Ii Receptor Blockers In Hypertension And Associated Risk Of Breast Cancer In Women, Darla R. Anderson

Nursing Capstones

No abstract provided.

Therapeutic Effect Of Steroids In Osmotic Demyelination Of Infancy., Lalit R. Bansal

Manuscripts, Articles, Book Chapters and Other Papers

An 11-month-old male presented with acute gastroenteritis, seizures, and altered mental status. Laboratory workup revealed serum sodium of 177 mmol/L. Magnetic resonance imaging of the brain showed reduced diffusion in the supratentorial white matter, T2 hyperintensities in the left central pons and midbrain, subacute stroke in the right occipital lobe, and bilateral cerebellar hemorrhagic infarcts. The child was presumed to have hypernatremia-induced central pontine and extrapontine myelinolysis. He received 5 days of high-dose methylprednisolone for persistent encephalopathy and spastic quadriparesis with rapid recovery of his cognitive function and neurological examination. The child remained seizure-free and achieved normal development at 3-month …

Applying Transition Theory To Preparation Of Experienced Nurses For New Clinical Roles, Ann M. Gill

Nursing Capstones

No abstract provided.

1st Place Contest Entry: Provisional Patent Research Process, Joshua Goldfaden

Kevin and Tam Ross Undergraduate Research Prize

This is Joshua Goldfaden's submission for the 2018 Kevin and Tam Ross Undergraduate Research Prize, which won first place. He wrote about abrasive chemicals in commercial toothpastes and created a provisional patent to develop a safer alternative.

Joshua is a sophomore at Chapman University, majoring in Biochemistry and Molecular Biology. His faculty mentor is Dr. Yu-An (Peter) Chang.