Medicine and Health Sciences Commons^™

Comparison Of The E Ects Of Diclofenac Potassium And Tenoxicam On Postoperative Pain, Swelling, And Trismus Following Third Molar Surgery, Ahmet Taylan Çebi̇, Meti̇n Berk Kasapoğlu, Seli̇n Eren, Çeti̇n Kasapoğlu

Turkish Journal of Medical Sciences

Background/aim: This study aimed to compare two nonsteroidal antiin ammatory agents in relation to pain, swelling, and trismus following impacted third molar surgery. Materials and methods: The study was a randomized and a double-blinded study and included 50 healthy individuals. A er the operation, patients were randomly assigned to 2 groups in which diclofenac potassium and tenoxicam were used. Impacted third molars were surgically extracted with local anesthesia. Pain was assessed postoperatively by visual analog scale at the 2nd, 6th, 8th, 12th, 24th, and 48th hours and on the 3rd, 5th, and 7th days. Swelling was evaluated using the method …

The Impact Of Visit-To-Visit Systolic Blood Pressure Variability On Residual Renal Function And Left Ventricular Hypertrophy In Peritoneal Dialysis Patients, Jun Ping Tian, Hong Wang, Xin Kui Tian, Feng He Du, Tao Wang

Turkish Journal of Medical Sciences

Background/aim: Blood pressure (BP) variability is more closely associated with adverse outcomes than 'usual' BP in the general population. Residual renal function (RRF) and left ventricular hypertrophy (LVH) are thought to be predictors of poor outcome in dialysis patients. However, only a few studies have focused on BP variation and its link to RRF, LVH, and outcome in peritoneal dialysis (PD) patients. therefore, we aimed to explore the e ect of visit-to-visit BP variability on RRF and LVH in continuous ambulatory PD (CAPD) patients. Materials and methods: We performed an observational study that included all prevalent PD patients between 1 …

Association Of Serum Leptin With Serum Estradiol In Relation To Breast Carcinogenesis: A Comparative Case-Control Study Between Pre- And Postmenopausal Women, Syed Danish Haseen Ahmed, Farah Idrees, Muhammad Ahsan, Aziza Khanam, Naheed Sultan, Naheed Akhter

Turkish Journal of Medical Sciences

Background/aim: The aims of this study were to observe the interhormonal relationship of serum leptin with serum estradiol and to compare pre- and postmenopausal women for possible implications in breast carcinogenesis. Materials and methods: This comparative case-control study encompasses 175 breast cancer patients and 175 age-, sex-, and BMI- matched healthy controls. For comparison, the subjects were divided into pre- and postmenopausal groups according to their menstrual history. Blood samples were analyzed for serum leptin and serum estradiol by the ELISA method. Results: Higher mean values of serum estrogen and leptin were observed in breast cancer cases among both the …

Pooled Analysis Of 163 Published Tuberculous Peritonitis Cases From Turkey, Bedi̇a Mutay Suntur, Feri̇t Kuşcu

Turkish Journal of Medical Sciences

Background/aim: Tuberculous peritonitis may be di cult to diagnose due to its insidious and variable clinical manifestations as well as characteristics similar to malignancy. In this study, case reports from Turkey over the last 10 years were reviewed systematically using pooled analysis. Materials and methods: irty-four suitable articles were found and 163 tuberculous peritonitis cases were included in the study. Results: e mean age was 34.1 years (17?79 years), and 146 (98.6%) of the patients were female and 17 (10.4%) were male. e most common complaints of these patients were abdominal pain (77.4%) and abdominal distention (73.5%). Ascites in the …

Low Levels Of Vitamin D Are Associated With Nosocomial Infections But Not With Short-Term Mortality In Critically Ill Patients, Işil Köse Güldoğan, Çi̇ler Zi̇nci̇rci̇oğlu, Hüseyi̇n Özkarakaş, Meltem Çakmak, Gürsel Ersan, Lütfi̇ye Kuzucu, Şükran Köse, Ni̇met Şenoğlu

Turkish Journal of Medical Sciences

Background/aim: A prospective observational study was conducted to determine the relationship between vitamin D de ciency and nosocomial infections among intensive care unit (ICU) patients. Materials and methods: Demographic data, season of admission, vitamin D levels at admission, premorbid lifestyle scores, comorbid conditions, and admission diagnosis were recorded in 306 ICU patients. Infections that developed at least 48 h a er admission to the ICU were the primary outcome, and ICU, hospital, and 1-year mortality were the secondary outcomes. Infections were evaluated for 28 days, and for the entire duration of ICU stay independently. Multiple logistic regression analysis was performed …

Effect Of Mometasone Furoate Nasal Spray On The Dna Of Nasal Mucosal Cells, Hakan Akkaş, Erdi̇nç Aydin, Seda Türkoğlu Babakurban, Erkan Yurtcu, Özlem Yilmaz Özbek

Turkish Journal of Medical Sciences

Background/aim: Allergic rhinitis (AR) is a respiratory disease caused by in ammation of the nasal mucosa. Intranasal corticosteroids (ICs) are an e ective treatment for AR; however, their use has been associated with atrophy in nasal mucosae. Because DNA damage has been linked to several chronic diseases, we hypothesize that use of ICs could cause DNA damage in nasal mucosa cells, leading to mucosal atrophy and septal perforation. Materials and methods: Sixty patients with moderate or severe AR were divided randomly into two groups. Mometasone furoate (MF) and antihistamine tablets (desloratadine) were given to the study (IC) group. Physiologic saline …

Obstructive Sleep Apnea Syndrome Is Associated With Impaired Pulmonary Artery Distensibility And Right Ventricular Systolic Dysfunction, Süha Çeti̇n, Mustafa Gökhan Vural, İbrahi̇m Hi̇kmet Firat, Ramazan Akdemi̇r

Turkish Journal of Medical Sciences

Background/aim: We investigated whether obstructive sleep apnea syndrome (OSAS) has any impact on pulmonary artery distensibility (PAD) and right ventricular (RV) function. Materials and methods: Subjects were categorized according to apnea?hypopnea index (AHI) as follows: controls (n = 17 and AHI < 5), mild-to-moderate OSAS (n = 22 and AHI = 5?30), and severe OSAS (n = 29 and AHI > 30). All subjects underwent transthoracic echocardiography a er polysomnography to assess PAD and RV function. PAD was recorded as M-Mode trace of the right pulmonary artery and was de ned as (PAmax ?PAmin/PAmin) × 100. S? was measured by means of TDI of the lateral annulus of the RV using apical four-chamber view. Results: Patients with severe OSAS demonstrated …

The Brazelton Neonatal Behavioral Assessment Scale: A Validity And Reliability Study In A Turkish Sample, Öznur Başdaş, Emi̇ne Erdem, Ferhan Elmali, Seli̇m Kurtoğlu

Turkish Journal of Medical Sciences

Background/aim: The aim of the Brazelton Neonatal Behavioral Assessment Scale (BNBAS) is to gather a comprehensive pro le of neonatal functioning by describing the full range of neonatal behavior, including competencies and strengths, as well as di culties or deviations. is instrument has proved to be of great clinical value by detecting infants at risk for later developmental problems. is work was conducted methodologically with the aim of a Turkish validity and reliability study of the BNBAS. Materials and methods: The study was conducted in a large tertiary hospital in Turkey. After establishing content and language validity, the BNBAS was …

The Relationship Between Vitamin D Deficiency And Erythrocyte Sedimentation Rate In Patients With Diabetes, Tezcan Kaya, Emi̇ne Ülkü Akçay, Zeynep Ertürk, Hasan Ergenç, Ali̇ Tamer

Turkish Journal of Medical Sciences

Background/aim: Vitamin D deficiency in diabetic patients has been shown to be associated with some in ammatory markers. However, its relationship with erythrocyte sedimentation rate (ESR) is still unknown. The aim of this study was to investigate the relationship between vitamin D deficiency and ESR in patients with type 2 diabetes mellitus (T2DM). Materials and methods: This cross-sectional study was conducted with 294 consecutive patients with T2DM. Serum levels of 25-hydroxyvitamin D, glycemic parameters, lipids, ESR, and C-reactive protein were measured. Patients were evaluated according to 25-hydroxyvitamin D levels as having vitamin D deficiency, vitamin D insuficiency, and vitamin D …

A Simplified Cell Culture Model For Research On Intestinal Inflammation, Ayşe Erol, Si̇bel Ti̇ryaki̇, Mustafa Orkan Ergün

Turkish Journal of Medical Sciences

Background/aim: e aim of this study was to combine some easy and economical de ned methods and constitute a comprehensive cell culture model to use in the bowel diseases characterized by in ammation. Materials and methods: Induction of inflammation was performed using lipopolysaccharide (LPS) or a cytokine mixture (TNF-?: 10 ng/mL; IFN-?: 100 ng/mL; IL-1ß: 1 ng/mL). IEC-6 cells were grown to con uence and serum-starved, wounds were constituted, and progress of cell migration into the wounds was photographed at 0, 2, 4, 6, 8, 10, 12, and 24 h in the presence or absence of an in ammatory environment. …

Comparison Between Iloprost And Alprostadil For Protection Againstischemia/Reperfusion Injury In A Rat Model, Deni̇z Çevi̇rme, Taylan Adademi̇r, Eylül Kafali Başaran, Ömer Faruk Şavluk, Ahmet Eli̇bol, Gözde Erkanli Şentürk, Hati̇ce Akkaya, Bayram Yilmaz

Turkish Journal of Medical Sciences

Background/aim: Alprostadil and iloprost are successful agents used for both pulmonary hypertension and extremity ischemia treatment. Different systemic effects of these agents may change the preferences of clinical usage. Superiority of preventing ischemia/ reperfusion (IR) injury is a criterion for clinical preference of these agents. The present study was designed to compare the protective effects of alprostadil and iloprost in a rat model of IR injury. Materials and methods: Twenty-three male Sprague Dawley rats were used (aged 8-12 weeks, mean weight 230 ± 30 g). They were randomized into 4 groups: Group 1 (iloprost + IR), Group 2 (alprostadil + …

Investigation Of Phikz Phage Therapy Against Pseudomonas Aeruginosa In Mousepneumonia Model, Kübra Can, Uğur Aksu, Osman Şadi̇ Yenen

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to investigate the effects of PhiKZ phage therapy and meropenem alone or combined treatments in a pneumonia mouse model induced by the Pseudomonas aeruginosa PAO1 strain. The cross-talk between lungs and kidneys was also determined. Materials and methods: The systemic, lung-specific, and kidney-specific inflammation levels and the bacterial load in lung tissue and biochemical parameters were investigated after PhiKZ phage therapy and meropenem alone or combined treatments in a pneumonia mouse model induced by the P. aeruginosa PAO1 strain. The cross-talk between lungs and kidneys was also determined by measuring plasma levels of …

Evaluation Of Two Commercial Assays For The Rapid Confirmation Of Oxa-48 Likecarbapenemases Produced By Klebsiella Pneumoniae, Pi̇nar Zarakolu, Abdullah Tarik Aslan, John Perry

Turkish Journal of Medical Sciences

No abstract provided.

A Retrospective Study Examining The Properties And Characteristicsof Dementia Patients In A Palliative Care Center, Meti̇n Di̇nçer

Turkish Journal of Medical Sciences

Background/aim: The aim of this study is to evaluate why dementia patients (DPs) are admitted to a palliative care center (PCC) and which factors affect the length of stay (LOS) of DPs in the PCC, and to predict the course of the disease. Materials and methods: The files of DPs were scanned retrospectively in the PCC between 2013 and 2016. Data related to age, sex, LOS, symptoms, clinical conditions, comorbidities, and prognosis were recorded. Results: The study included 85 DPs with a mean age of 84.1 ± 6.7 years. LOS was determined as a median of 15.0 days. While LOS …

Human Immunodeficiency Virus And Tuberculosis Coinfection: Clinical Features And Predictors Of Mortality, Fatma Gümüşer, Merve Altinkaynak, Di̇lek Yildiz Sevgi̇, Özlem Altuntaş Aydin, Bi̇lgül Mete, Alper Gündüz, Hayat Kumbasar Karaosmanoğlu, Si̇bel Bolukçu, Ömer Fehmi̇ Tabak, Mustafa Haluk Vahaboğlu

Turkish Journal of Medical Sciences

Background/aim: This study was undertaken to identify subjects with human immunodeficiency virus and tuberculosis (HIV/TB) coinfection in a group of HIV-positive patients followed at five different healthcare centers, and to determine the demographic and clinical characteristics of these subjects as well as the predictors of mortality. Materials and methods: A database search for subjects with TB coinfection was performed among 1475 HIV-positive adult patients and a total of 66 individuals were identified with HIV/TB coinfection. Results: There were 66 patients (4.5%) with TB coinfection. Twenty-one percent (n = 14) of the patients with TB coinfection died during the study period …

Saliva Levels Of Caspase-1, Tnf-α, And Ifn-γ In Primary Sjögren's Syndrome: Oralmucosal Abnormalities Revisited, Gonca Karabulut, Gül Ki̇tapçioğlu, Özgün Özçaka, Esi̇n Alpöz, Ayşe Nalbantsoy, Hayri̇ye Koçanaoğullari, Sercan Gücenmez, Gökhan Keser, Yasemi̇n Kabasakal

Turkish Journal of Medical Sciences

Background/aim: Abnormalities in oral mucosal immunity contribute to complex pathogenesis of primary Sjögren's syndrome (pSjS). We aimed to measure saliva and serum levels of caspase-1, tumor necrosis factor-alpha (TNF-α) and interferon gamma (IFN-γ) in patients with pSjS. Materials and methods: We studied 43 pSjS patients fulfilling the AECG criteria and 30 age/sex-matched healthy controls, as well as 39 rheumatoid arthritis (RA) patients as a disease control group. ESSDAI scores were less than seven in all patients with pSjS, indicating low disease activity. Quantitative analyses were made in serum and whole saliva samples. The statistical analysis was performed using SPSS 19.0. …

Positive Correlation Of Galanin With Insulin Resistance And Triglyceride Levels In Obesechildren, Sezer Acar, Ahu Paketçi̇, Tuncay Küme, Korcan Demi̇r, Özlem Gürsoy Çalan, Ece Böber, Ayhan Abaci

Turkish Journal of Medical Sciences

Background/aim: Galanin is a neuropeptide that is shown to be involved in the regulation of food intake and glucose homeostasis. The objective of this study was to evaluate the relation of serum galanin levels with anthropometric and metabolic parameters in obese and healthy children. Material and methods: The cross-sectional study consisted of 38 obese children (mean age: 11.9 ± 3.0 years) and 30 healthy children (mean age: 11.4 ± 2.0 years). Clinical and biochemical parameters [glucose, insulin, homeostasis model assessment-insulin resistance (HOMA-IR), lipids, galanin, and leptin levels] were assessed. Results: Serum galanin and leptin levels were significantly higher in obese …

Perioperative Complications And Short-Term Outcomes Of Abdominal Sacrocolpopexy,Laparoscopic Sacrocolpopexy, Sacrospinous Ligament Fixation,And Iliococcygeus Fixation Procedures, Alper Bi̇ler, İbrahi̇m Egemen Ertaş, Gökhan Tosun, İsmet Hortu, Ahmet Demi̇r, Cüneyt Eftal Taner, Mehmet Özeren, Fati̇h Şendağ

Turkish Journal of Medical Sciences

Background/aim: This study aimed to investigate differences in perioperative complications and short-term outcomes of patients who underwent abdominal sacrocolpopexy/sacrohysteropexy, laparoscopic sacrocolpopexy/sacrohysteropexy, sacrospinous ligament fixation (SSLF), and iliococcygeus fixation due to apical prolapse. Materials and methods: The present retrospective cohort study included 145 patients who underwent apical prolapse surgery performed by the same surgeons between 1/1/2011 and 30/6/2017. There were 68 abdominal sacrocolpopexies (44 sacrocolpopexies and 24 sacrohysteropexies), 13 laparoscopic sacrocolpopexies (10 sacrocolpopexies and 3 sacrohysteropexies), 57 SSLFs, and 7 iliococcygeus fixations. Patients' short-term outcomes, perioperative complications, blood loss, operative time, and hospital stay were analyzed. Results: The mean operating time …

Exploring The Role Of Mirnas In The Diagnosis Of Mody3, Oğuzhan Fati̇h Baltaci, Şeyma Çolakoğlu, Gökçe Güllü Amuran, Nesli̇han Aydin, Mehmet Sarğin, Arzu Karabay Korkmaz, Mehmet Temel Yilmaz, Ergül Berber

Turkish Journal of Medical Sciences

Background/aim: MODY3 associated with HNF1A is the most common form of MODY and is clinically misdiagnosed as type 1 diabetes due to similar clinical symptoms. This study aimed to analyze the role of HNF1A-regulated miRNAs as a biomarker in the diagnosis of MODY3. Materials and methods: MIN6 cells were transfected with the HNF1A cDNA expression vector for overexpression or with siRNA specific to HNF1A to silence its expression. The HNF1A-regulated miRNAs were determined by RNA-Seq of the total RNA extract. Expressions of the candidate miRNAs in blood samples of MODY3, type 1 diabetes, and type 2 diabetes patients and in …

Se33 Locus As A Reliable Genetic Marker For Forensic Dna Analysis Systems, Dr Munir Ahmad Bhinder, Muhammad Yasir Zahoor, Haleema Sadia, Muhammad Qasim, Rukhsana Perveen, Ghulam Murtaza Anjum, Muhammad Iqbal, Najeeb Ullah, Waseem Shehzad, Muhammad Tariq, Ali Muhammad Waryah

Turkish Journal of Medical Sciences

Background/aim: Genetic variation, an authentic tool of individual discrimination, is being used for forensic investigations worldwide. A missing result for even one out of 13-17 markers leads to an inconclusive report. Additional reliable markers are required to compensate such deficiencies. The SE33 locus has high genetic variability in different populations and is being used in forensic investigation systems in some countries. The purpose of the study was to assess the viability of use of the SE33 locus as a supportive marker for forensic DNA profiling. Materials and methods: Amplification of the SE33 locus was performed using the PowerPlex ES Monoplex …

Effect Of Phosphodiesterase-5 Inhibition On Joint And Muscle Damage In Rats Withadjuvant Arthritis, Fai̇ze Eli̇f Bahadir, Mustafa Kutay Köroğlu, Meral Yüksel, Feri̇ha Ercan, Yaşar İnci̇ Ali̇can

Turkish Journal of Medical Sciences

Background/aim: This study was designed to examine the effect of tadalafil, a phosphodiesterase (PDE)5 inhibitor, on the severity of joint and muscle damage in rats with adjuvant-induced arthritis (AA). Materials and methods: AA was induced by intradermal inoculation into right hind paw of male Sprague Dawley rats (300-450g) with complete Freund's adjuvant (CFA; 0.1 mL). AA rats were treated with either tadalafil (10 mg/kg; per oral) alone or along with the soluble guanylyl cyclase inhibitor 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one (ODQ; 10 mg/kg; intraperitoneally). After decapitation on day 16, trunk blood was collected for total oxidant status (TOS) and total antioxidant capacity (TAC) assays. …

Effect Of Cineole, Alpha-Pinene, And Camphor On Survivability Of Skin Flaps, Bi̇lsev İnce, Mehmet Dadaci, İbrahi̇m Kilinç, Pembe Oltulu, Serhat Yarar, Mehmet Uyar

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to determine the specific component of Rosmarinus officinalis (RO) responsible for increased flap survival and how RO displays its efficacy. Materials and methods: Rectangular random-pattern flaps were elevated from the back of each rat. Group I was the control group. In group II 0.1 mL of cineole, in group III 0.1 mL of alpha-pinene, in group IV 0.1 mL of camphor, in group V 0.1 mL each of alpha-pinene and cineole, in group VI 0.1 mL each of alpha-pinene and camphor, in group VII 0.1 mL each of cineole and camphor, and in …

The Effect Of Low Molecular Weight Heparin On Salvaging The Zone Of Stasis In Anexperimental Burn Model, Muhammet Uraloğlu, Murat Li̇vaoğlu, Özgür Agdoğan, Şafak Ersöz, Ümi̇t Naci̇ Karaçal

Turkish Journal of Medical Sciences

Background/aim: Multiple zones of injuries are formed after burns, consisting of a zone of coagulative necrosis, a zone of hyperemia, and a zone of stasis, in which progressive microcirculatory thrombosis leads to degeneration and deepening of the wound. We used an experimental rat comb burn model to test the hypothesis that use of low molecular weight heparin (LMWH) may save the zone of stasis. Materials and methods: Adult female rats were randomly divided two groups: the LMWH group (n = 8) rats received subcutaneous LMWH injections, while the saline group (n = 8) rats were injected with the same volume …

Understanding Ttp, Alexis L. Koester

Natural Sciences Student Research Presentations

This poster for the Natural Sciences Poster Session summarizes Thrombotic thrombocytopenic purpura (TTP), a rare autoimmune disorder, either inherited or acquired, that produces antibodies affecting the gene ADAMTS13, which causes bleeding and inhibits blood clotting. Symptoms include purple bruising (purpura) and small red dots on the skin, called petechiae. Untreated TTP can lead to damage in the brain, heart and kidneys.

Propafenone (Rythmol), Maria Figueiredo

Natural Sciences Student Research Presentations

For this poster presented at the Natural Science Poster Session at Parkland College, the student chose the drug Propafenone, also known as Rythmol, whose labeled uses are to treat ventricular arrhythmias, atrial fibrillation, and paroxysmal supraventricular tachicardia. Chemical information, identification, and effects on the body are also included on the poster.

A Rapid, Handheld Device To Assess Respiratory Resistance: Clinical And Normative Evidence, Aaron B. Holley, Wesley D. Boose, Michael Perkins, Karen L. Sheikh, Nancy P. Solomon, Angela M. Dietsch, Jafar Vossoughi, Arthur T. Johnson, Jacob F. Collen

Department of Special Education and Communication Disorders: Faculty Publications

Introduction: Following reports of respiratory symptoms among service members returning from deployment to South West Asia (SWA), an expert panel recommended pre-deployment spirometry be used to assess disease burden. Unfortunately, testing with spirometry is high cost and time-consuming. The airflow perturbation device (APD) is a handheld monitor that rapidly measures respiratory resistance (APD-R_r) and has promising but limited clinical data. Its speed and portability make it ideally suited for large volume pre-deployment screening. We conducted a pilot study to assess APD performance characteristics and develop normative values.

Materials and Methods: We prospectively enrolled subjects and derived …

My Client Knows That He’S About To Stutter: How Can We Address Stuttering Anticipation During Therapy With Young People Who Stutter?, Eric S. Jackson, Hope Gerlach, Naomi H. Rodgers, Patricia M. Zebrowski

Department of Special Education and Communication Disorders: Faculty Publications

Stuttering anticipation is endorsed by many people who stutter as a core aspect of the stuttering experience. Anticipation is primarily a covert phenomenon and people who stutter respond to anticipation in a variety of ways. At the same time as anticipation occurs and develops internally, for many individuals the “knowing” or “feeling” that they are about to stutter is a primary contributor to the chronicity of the disorder. In this article, we offer a roadmap for both understanding the phenomenon of anticipation and its relevance to stuttering development. We introduce the Stuttering Anticipation Scale (SAS)—a 25-item clinical tool that can …

Resilience Concepts In Psychiatry Demonstrated With Bipolar Disorder, David G. Angeler, Craig R. Allen, Maj-Liz Persson

Nebraska Cooperative Fish and Wildlife Research Unit: Staff Publications

Background: The term resilience describes stress–response patterns of subjects across scientific disciplines. In ecology, advances have been made to clearly distinguish resilience definitions based on underlying mechanistic assumptions. Engineering resilience (rebound) is used for describing the ability of subjects to recover from adverse conditions (disturbances), and is the rate of recovery. In contrast, the ecological resilience definition considers a systemic change: when complex systems (including humans) respond to disturbances by reorganizing into a new regime (stable state) where structural and functional aspects have fundamentally changed relative to the prior regime. In this context, resilience is an emergent property of complex …

Communicating Nutrition Information At The Point Of Purchase: An Eye‐Tracking Study Of Shoppers At Two Grocery Stores In The United States, Mike Bartels, Katherin Tillack, Chung‐Tung Jordan Lin

United States Food and Drug Administration: Publications

Providing nutrition information at the point of purchase is one approach that can be used to help consumers adopt and maintain a healthy diet. Previous research has examined consumer self‐reported notice and use of the information as well as how the design of the information affects its attention and use in a laboratory environ‐ ment using eye‐tracking methodology. This study advances the literature by applying eye‐tracking methodology to explore consumer visual and choice behavior in a real shopping environment, and by recognizing that nutrition information competes with other visual stimuli in the store and consumers are vulnerable to a “limited …

Micropublication: Incentivizing Community Curation And Placing Unpublished Data Into The Public Domain, Daniela Raciti, Karen Yook, Todd W Harris, Tim Schedl, Paul W Sternberg

2010-2019 OA Pubs

UNLABELLED: Large volumes of data generated by research laboratories coupled with the required effort and cost of curation present a significant barrier to inclusion of these data in authoritative community databases. Further, many publicly funded experimental observations remain invisible to curation simply because they are never published: results often do not fit within the scope of a standard publication; trainee-generated data are forgotten when the experimenter (e.g. student, post-doc) leaves the lab; results are omitted from science narratives due to publication bias where certain results are considered irrelevant for the publication. While authors are in the best position to curate …