Medicine and Health Sciences Commons^™

A Preliminary Investigation Of Trunk And Wrist Kinematics When Using Drivers With Different Shaft Properties, C Joyce, A Burnett, J Cochrane, A Reyes

Health Sciences Papers and Journal Articles

It is unknown whether skilled golfers will modify their kinematics when using drivers of different shaft properties. This study aimed to firstly, determine if golf swing kinematics and swing parameters and related launch conditions differed when using modified drivers, then secondly, determine which kinematics were associated with clubhead speed. Twenty high level amateur male golfers (Mean ± SD: handicap = 1.9 ± 1.9 score) had their three-dimensional trunk and wrist kinematics collected for two driver trials. Swing parameters and related launch conditions were collected using a launch monitor. A one-way repeated measures ANOVA revealed significant (p ≤ 0.003) between-driver differences; …

Preferential Mobilization And Egress Of Type 1 And Type 3 Innate Lymphocytes In Response To Exercise And Hypoxia, I Ng, T Fairchild, W Greene, G Hoyne

Health Sciences Papers and Journal Articles

The study examined the effect of exercise and hypoxia on the mobilization and egress of innate lymphocytes (ILCs) and adaptive T cell populations in the blood. The ILCs have emerged as a critical population of cells in immune regulation at mucosal surfaces in animals and humans. Eleven healthy male subjects performed (i) 45 min of exercise at 50% VO2 peak on a cycle ergometer under normoxia and (ii) hypoxia, or (iii) while resting in hypoxia. Blood samples were obtained pre-exercise, immediately post-exercise and 60 min post-exercise and were analyzed by flow cytometry to examine the type 1 and type 3 …

Male Or Nurse What Comes First? Challenges Men Face On Their Journey To Nurse Registration, D Juliff, K Russell, C Bulsara

Health Sciences Papers and Journal Articles

Objective: This paper aims to provide an account of the first phase of a qualitative longitudinal study that explored the initial challenges men in nursing face to become registered. What is known is that men, a minority group within nursing, face the usual challenges of all new nurses in their quest to register as nurses. In addition, they have added pressures that hinder their quest due to being male.

Primary Argument: An Australian nursing shortage is looming due to nurses retiring from this female-dominate profession. Hence, the retention of men in nursing is an area requiring attention in order to …

Plasmodium Falciparum Hep1 Is Required To Prevent The Self Aggregation Of Pfhsp70-3, D Nyakundi, L Vuko, S Bentley, H Hoppe, G Blatch, A Boshoff

Health Sciences Papers and Journal Articles

The majority of mitochondrial proteins are encoded in the nucleus and need to be imported from the cytosol into the mitochondria, and molecular chaperones play a key role in the efficient translocation and proper folding of these proteins in the matrix. One such molecular chaperone is the eukaryotic mitochondrial heat shock protein 70 (Hsp70); however, it is prone to self-aggregation and requires the presence of an essential zinc-finger protein, Hsp70-escort protein 1 (Hep1), to maintain its structure and function. PfHsp70-3, the only Hsp70 predicted to localize in the mitochondria of P. falciparum, may also rely on a Hep1 orthologue to …

Structural And Functional Characterization Of Enzymes Of A Novel Group Of Tryptophylquinone Cofactor Containing Oxidases, Esha Sehanobish

Electronic Theses and Dissertations

Protein-derived cofactors are redox and catalytic centers that are generally formed by the posttranslational modifications of one or more amino acids. An important class of these cofactors are the quinones derived from tyrosine and tryptophan. Amongst redox proteins, it has been known till now that oxidases either contain a flavin or a tyrosylquinone cofactor, whereas tryptophylquinone ones are present within the dehydrogenases. In recent times, oxidases from a marine bacterium, Marinomonas mediterranea, have been shown to possess the latter. This study involves the characterization of two such proteins, lysine-?-oxidase (LodA) and glycine oxidase (GoxA). They have been reported to contain …

Diaphragm Training And Evaluation As A Therapeutic Tool By Athletic Trainers In Orthopedic Rehabilition, Marisa Rashel Foltz

Graduate Theses/Dissertations

Athletic trainers (AT) incorporate diaphragm training techniques into treatment protocols; however, further understanding of the techniques’ purpose and application is needed. An investigation of clinical reasoning for use of diaphragm training and evaluation as therapeutic tools in rehabilitation was conducted. Research questions sought to identify AT perspectives and rationale for incorporating these techniques, explore how ATs gain knowledge, and identify evaluation and educational methods utilized in rehabilitation. A qualitative investigation employing a phenomenological approach was used to address the research questions. Procedures included convenience sampling, one-on-one semi structured interviews, transcription, and coding that led to overall theme development. Thirteen ATs …

Identification And Characterization Of Dna Repair Snf2/Swi2 Atpases In Tetrahymena Thermophila, Andrew Francis Morin

Graduate Theses/Dissertations

The Snf2/Swi2 ATPases Rad5 and Rad16 have been shown to play vital roles in a number of DNA repair pathways. In both Saccharomyces cerevisiae and human cell lines, Rad5 homologs (SHPRH, HLTF) have been shown to function in DNA double strand break (DSB) repair along with pathways that repair damage after replication. The function of Rad16, unlike Rad5, has been found only in lower eukaryotes such as Saccharomyces, despite the fact that it plays an essential role in nucleotide excision repair (NER), and more specifically in the repair of silenced areas of the genome. In order to more fully understand …

Differences In Patient Outcomes Of Prevalence, Interval, And Screen-Detected Lung Cancers In The Ct Arm Of The National Lung Screening Trial, Matthew B. Schabath, Pierre P. Massion, Zachary J. Thompson, Steven A. Eschrich, Yoganand Balagurunathan, Dmitry Goldof, Denise R. Aberle, Robert J. Gillies

Computer Science and Engineering Faculty Publications

Lung cancer screening identifies cancers with heterogeneous behaviors. Some lung cancers will be identified among patients who had prior negative CT screens and upon follow-up scans develop a de novo nodule that was determined to be cancerous. Other lung cancers will be identified among patients who had one or more prior stable positive scans that were not determined to be lung cancer (indeterminate pulmonary nodules), but in follow-up scans was diagnosed with an incidence lung cancer. Using data from the CT arm of the National Lung Screening Trial, this analysis investigated differences in patient characteristics and survival endpoints between prevalence-, …

Turn-Around-Time Improvements For Positive Blood Cultures From Incorporation Of Workflow Modifications, Brent Bobik, Allison F. Goldberg, Md, P. Prior, Amity L. Roberts, Phd, D(Abmm)

Department of Pathology, Anatomy, and Cell Biology Resident's Posters

Background:

Emergence of direct from positive blood culture bottle identification (ID) methods reveal opportunities for improving bacterial ID and select resistance marker detection turn-around-times. Each system has various advantages and disadvantages; each institution must select the method/s that best fit the laboratory and patient needs. Here we elucidate improvements in 24 hour workflow through incorporating multiple rapid technologies for positive blood culture ID into a 24 hour algorithm.

Methods:

MALDI-TOF (Bruker) analysis with sepsityper extraction (aerobic Gram-positive and anaerobic bacteria); MALDI-TOF analysis with serum separator tube concentration (Gram-negative bacteria); and a FilmArray Blood Culture Panel (Biofire) were utilized. MALDI was …

Adolescent Mothers’ Implementation Of Strategies To Enhance Their Children’S Early Language And Emergent Literacy Skills, Meredith C. Canty

Honors Undergraduate Theses

Previous studies have examined how the language skills of children with adolescent mothers differs from children of older mothers. However, there is limited information on what specific strategies adolescent mothers utilize to increase early language and emergent literacy skills in their children. The aim of the present study is to examine adolescent mothers’ use of strategies to increase the early language and emergent literacy skills of their young children. A sample of 14 adolescent mothers enrolled in a teen parenting program were surveyed on their use of common strategies that are shown to facilitate early development of language and literacy …

Pharmacogenomic Management Of Familial Hypercholesterolemia: An Integrative Review Of The Literature, Brian V. Skibo

Honors Undergraduate Theses

The purpose of this thesis is to examine familial hypercholesterolemia (FH) and emerging pharmacogenomics therapies that propose to lower serum low density lipid (LDL) levels. The search of various data bases resulted in nine research articles being selected for review. Syntheses of the articles suggest emerging phamacogenomic drug therapy can improve treatment outcomes for individuals with a diagnosis of FH. The Human Genome Project (HGP) has had far reaching applications for genomic technologies and pharmacagenomic interventions, tailored to human conditions associated with select genomic traits. Synthesis of nine research articles demonstrate that little is known on the topic and reveals …

Nursing Knowledge And Perceived Comfort Level In Acute Infusion Reactions From Antineoplastic Agents, Andrea L. Maiorini

Honors Undergraduate Theses

INTRODUCTION: Acute infusion reactions from antineoplastic agents can include hypersensitivity reactions, anaphylaxis, and cytokine release infusion reactions. Severe acute infusion reactions happen in about 5% of the oncology patient population and nurses are responsible for assessment and management of the reaction. This is a high-stress task for a nurse magnified by the lack of exposure. This project explores nursing knowledge and perceived comfort level of acute infusion reactions caused by antineoplastic agents.

METHODOLOGY: An original survey was created to test nursing knowledge and assess comfort level. Nursing knowledge was broken down into six subscales: general knowledge of acute infusion reactions, …

Retention Of Cardiopulmonary Resuscitation Knowledge And Psychomotor Skill Among Undergraduate Nursing Students: An Integrative Review Of Literature, Fernanda Tirado

Honors Undergraduate Theses

Purpose: The purpose of this integrative literature review is to explore the effectiveness of different training modalities on the acquisition and retention of CPR knowledge and psychomotor skill among undergraduate nursing students. Background: It is well known that standard CPR-training is ineffective at preparing nurses for the rigors of a cardiac arrest event. Survival rates for in-hospital cardiac arrests remain low and the proportion of neurobehavioral sequelae among survivors is very high. Methods: A review of relevant literature published between 2006 and 2016 was conducted using the CINAHL and MEDLINE databases. The following key terms were used in the search: …

Participant's Perception Of Realism And Pediatric Pain Assessment Utilizing A Virtual Patient: A Pilot Study, Alexandra Carson

Honors Undergraduate Theses

The use of simulation in curriculum affords students with the opportunity to enhance clinical skills in a safe environment. However, certain aspects of patient assessment are difficult to reproduce in current simulators, such as changes in facial expressions. Facial expressions are of particular importance when assessing for the presence and severity of pain in the pediatric population. Inconsistencies found in accurate identification of pain suggest the necessity of improved pain assessment training. This study evaluated nursing student’s perceptions of a virtual patient designed to realistically display varying levels of pain in the pediatric patient. Additional purposes of this study were …

Behavioral Interventions Versus Pharmaceutical Interventions To Reduce Preoperative Anxiety In School Aged Children, Jennifer J. Cline

Honors Undergraduate Theses

Surgical procedures that require general anesthesia can be stressful and create needless anxiety for school-age children. Interventions aimed at reducing preoperative anxiety can improve cooperation and enhance postoperative outcomes by lowering anxiety levels prior to induction of general anesthesia. The purpose of this study was to examine the effects of behavioral interventions versus drug therapy in reducing pre-operative anxiety in children. The secondary purpose was to compare methods used to integrate anxiety reduction interventions into pre-operative care and to evaluate the most widely used and effective strategy for clinical practice. A literature review exploring behavioral based stress reduction interventions and …

Exploring The Art Of Nursing And Its Influence On Patient Satisfaction In Acute Care Settings, Enid Tirado

Honors Undergraduate Theses

‎Nursing is a trusted profession aimed at delivering quality, patient-centered care perceived by patients as caring and satisfactory. While empiric care components are measurable as associated with clinical outcomes, patients’ perceptions of care are increasingly important in determining satisfaction with the patient care experience. Not clearly defined, nor empirically measurable, the “art” of nursing is taking on increasing importance as a component of satisfaction with the patient experience. The purpose of this integrative literature review was to review the literature in order to find common themes influencing determination of the art of nursing on patient satisfaction in acute care settings. …

Intensive Care In Oncology: Admission And Outcomes In Adult Patients With Cancer, Surya John

Honors Undergraduate Theses

Background: Historically, patients with cancer have been perceived as poor candidates for ICU admission. General ICU admission criteria lists cancer patients as low priority in ICU admission depriving them of the care they rightfully deserve. The purpose of this literary synthesis was to examine ICU admission criteria, risk factors, and outcomes of ICU admission in relation to hematological and solid tumor cancers and discuss ways that practitioners and nurses can educate patients with cancer and their families on appropriateness of ICU care.

Methods: A total of 768 articles were found in a literature search including all literature from 2005 to …

The Effect Of Alternative Labor Positions Versus The Lithotomy Position On Birthing Outcomes: An Integrative Literature Review, Kelsey Gaffka

Honors Undergraduate Theses

Traditionally, the lithotomy position is the most commonly used birthing position in western cultures. The purpose of this literature review was to examine the differences in maternal and neonatal outcomes when alternative labor positions are used. Implications for future use of alternative labor positions were explored. Peer reviewed, English-language research articles published from 2009 to 2015 were included for synthesis. Study results revealed that the lithotomy position is linked to multiple negative maternal outcomes. Birthing in a water pool or in a lateral position has been linked to more optimal maternal and neonatal outcomes compared to other positions. Health care …

Dosing Accuracy When Administering Oral Medications, Chelsea Hughes

Honors Undergraduate Theses

Inaccurate dosing of children’s liquid medication is a major problem that causes adverse effects for children every year. In order to prevent these errors, education for at risk parents is essential. A survey and observational study was done in order to identify parents/caregivers who make dosing errors when measuring out liquid medication for their children. A total of 25 parents/caregivers with children admitted to Arnold Palmer Hospital were included in this study. Study participants completed a survey that included demographic data as well as parenting experience. The parents were directly observed measuring a dose of corn syrup using Children’s liquid …

Expression Levels Of Virulence Genes In Group A Streptococci: A Response To Aerosolized Propylene Glycol, Michael S. Costello

Honors Undergraduate Theses

Electronic cigarette usage is becoming increasingly prevalent among school age children and young adults. A known bactericidal agent, propylene glycol, is often used as a carrier for nicotine, flavoring, and additional constituents of electronic cigarette juice. This study examined the relationship between propylene glycol and virulence gene expression in Streptococcus pyogenes, a respiratory tract pathogen commonly found in school-age individuals. A variety of virulence genes controlled by the three stand alone regulators mga, RofA, and Rgg/RopB were sampled in an effort to understand the pathway by which virulence is affected. The genes chosen encode C5a peptidase, fibronectin binding protein, hyaluronate …

Exploring Supported Conversation With Familial Caregivers Of Persons With Memory Impairment: A Pilot Study, Arielle Willis

Honors Undergraduate Theses

Teaching conversational strategies has been effective for a wide array of clients with acquired neurologic disorders and their caregivers. Research indicates positive results for Supported Conversation in adults with Aphasia (SCA) secondary to stroke. Applying this method to work with caregivers of persons with memory impairment could prove to be a valid intervention tool. This investigation will examine the applicability of SCA with persons with memory impairment and their familial caregivers. This pilot study is intended to create a conversation regarding SCA and its implementation with persons with memory impairment who still live in the community with their caregivers. Analysis …

The Effect Of Aphasia On Quality Of Life, Coping Style, And Resilience, Nelson J. Hernandez

Honors Undergraduate Theses

Approximately one million people in the United States suffer from aphasia. There are multiple types of aphasia, however they are usually placed into two categories: non-fluent or fluent. The psychosocial factors that are impacted due to the type of aphasia has not been systematically investigated. The purpose of this study is to examine how non-fluent and fluent Individuals With Aphasia (IWA) compare or contrast across three psychosocial factors, Quality of Life (QoL), coping style, and resilience. The World Health Quality of Life- BREF (WHOQOL-BREF), Assimilative-Accommodative Coping Scale (AACS), and the Connor-Davidson Resilience Scale-10 item version (CD-RISC-10), were administered once to …

An Instrument To Measure Dental Students' Communication Skills With Patients In Six Specific Circumstances: An Exploratory Factor Analysis, Joanna Alice Aalboe, Mitzi M. Schumacher

Center for Oral Health Research Faculty Publications

The aim of this study was to explore the internal structure of an instrument assessing dental students' confidence in their ability to communicate with patients in six specific circumstances (anxious, in pain, etc.) using exploratory factor analysis. In a Communication in the Dental Health Care Setting course at a U.S. dental school, second-year dental students in two years (2013 and 2014) responded to the six items on a survey instrument. Of the total 123 students, 122 fully completed the instrument, for a response rate of 99%. Analysis of the results identified a unidimensional scale with regards to patient-specific communication self-efficacy …

Chronic Pancreatitis, Pain, And Anxiety In An Alcohol And High Fat Mouse Model, Tiffanie Clinkinbeard

Theses and Dissertations--Gerontology

Homeodynamic space (HDS) shrinks as vulnerability increases with aging and repeated damage to the cells. HDS is lost in alcoholic pancreatitis patients due to overconsumption of alcohol, smoking, and high fat diets. Etiologically relevant animal models for study of chronic pancreatitis (CP) are needed. In order to begin filling this gap a central purpose of this dissertation research was to examine relationships between the alcohol and high fat diet (AHF) and pancreatitis with attention to hypersensitivity and anxiety-like behaviors. The AHF diet induced pancreatitis described here etiologically mimics human risk factors of AHF consumption for advancement to alcoholic CP.

In …

Molecular Genetics Of Ms4a6a And Alzheimer's Disease, Ryan Harpole

Lewis Honors College Capstone Collection

Increased Alzheimer’s disease (AD) risk has previously been associated with a SNP called rs610932 near the gene MS4A6A. The goal of this experiment was to quantify the expression of two MS4A6A isoforms in the brains of AD and non-AD subjects, particularly as a function of rs610932 genotype. According to an article titled “Alzheimer’s Disease Susceptibility Variants in the MS4A6A Gene are Associated with Altered Levels of MS4A6A Expression in Blood”, MS4A6A has four different isoforms that have been reported to be differentially expressed in the blood of AD subjects compared to non-AD subjects (Petroula et al., 2014). After statistically …

Evaluation Of Resin Sealer Penetration Of Dentin Following Different Final Rinses For Endodontic Irrigation Using Confocal Laser Scanning Microscopy, Omar Ezzaldin Abusteit

MUSC Theses and Dissertations

Introduction: The aim of the study was to directly assess the depth of sealer penetration into dentinal tubules following different final rinses and indirectly evaluate precipitation of irrigating solutions. Materials and Methods: 52 extracted maxillary incisors were prepared to size 40/04 crown down with 6% sodium hypochlorite irrigating solution. Teeth were randomly divided into 4 groups (n=13) according to the final rinse. Group 1- 17% EDTA, saline and 2% Chlorhexidine solution; Group 2- SmearOFFâ„¢; Group 3- QMix®; Group 4- control with saline. Each final rinse was 3 ml over 1 minute placed with a 30-gauge needle 3 mm short from …

Linking Emr To Virtual Care Of Psychiatric Patients In The Acute Care Setting, Howard Louis Beatty Jr.

MUSC Theses and Dissertations

The purpose of this study is to test if the implementation of the Tele-Psychiatric Consultation Process (built within the FirstNet (Cerner/EMR) application, which pulls the patient’s current EMR encounter from multiple facility locations to a different physical facility location for consultation) provided increased quality by decreasing in total length of stay. The coordination of virtual care consultations allows for inter-practice data exchange for multi-provider clinical decision support. Documentation of medications and treatment regimens, which may be unfamiliar to the acute care provider, are provided through virtual tele-psychiatric consultations. An eTracking queue within FirstNet was built in-house by Carolinas Healthcare System …

The Impact Of General Strike On Government Healthcare Delivery In Kerala State In India, Aasems Jacob, Heidi L. Weiss, Aju Mathew

Markey Cancer Center Faculty Publications

General strike (also known as hartal) is used as a mode of protest by organizations and political parties in India. It is generally thought that hartals negatively impact the healthcare delivery in a society. We used the Right to Information Act to obtain data from government health centers in Kerala state in India for four hartal days (H-day) and two control days (A-day and B-day) for each H-day, from sixteen health centers including 6 Community Health Center (CHC), 6 Secondary Health Center (SHC), and 4 Tertiary Health Center (THC). Data on emergency room visits was available for six HCs. 15 …

Molecular Cause And Functional Impact Of Altered Synaptic Lipid Signaling Due To A Prg-1 Gene Snp, Johannes Vogt, Jenq-Wei Yang, Arian Mobascher, Jin Cheng, Yunbo Li, Xingfeng Liu, Jan Baumgart, Carine Thalman, Sergei Kirischuk, Petr Unichenko, Guilherme Horta, Konstantin Radyushkin, Albrecht Stroh, Sebastian Richers, Nassim Sahragard, Ute Distler, Stefan Tenzer, Lianyong Qiao, Klaus Lieb, Oliver Tüscher, Harald Binder, Nerea Ferreiros, Irmgard Tegeder, Andrew J. Morris, Sergiu Gropa, Peter Nürnberg, Mohammad R. Toliat, Georg Winterer, Heiko J. Luhmann, Jisen Huai, Robert Nitsch

Gill Heart & Vascular Institute Faculty Publications

Loss of plasticity‐related gene 1 (PRG‐1), which regulates synaptic phospholipid signaling, leads to hyperexcitability via increased glutamate release altering excitation/inhibition (E/I) balance in cortical networks. A recently reported SNP in prg‐1 (R345T/mutPRG‐1) affects ~5 million European and US citizens in a monoallelic variant. Our studies show that this mutation leads to a loss‐of‐PRG‐1 function at the synapse due to its inability to control lysophosphatidic acid (LPA) levels via a cellular uptake mechanism which appears to depend on proper glycosylation altered by this SNP. PRG‐1^+/− mice, which are animal correlates of human PRG‐1^+/mut carriers, showed an altered cortical network …

Table Of Contents 2016 Nebraska Beef Cattle Report

Nebraska Beef Cattle Reports

No abstract provided.