Medicine and Health Sciences Commons^™

Acc Neuro-Over-Connectivity Is Associated With Mathematically Modeled Additional Encoding Operations Of Schizophrenia Stroop-Task Performance, Reggie Taylor, Jean Theberge, Peter C Williamson, Maria Densmore, Richard W J Neufeld

Department of Medicine Publications

Functional magnetic resonance imaging at 7.0 Tesla was undertaken among Schizophrenia participants (Sz), and clinical (major mood disorder; MDD) and healthy controls (HC), during performance of the Stoop task. Stroop conditions included congruent and incongruent word color items, color-only items, and word-only items. Previous modeling results extended to this most widely used selective-attention task. All groups executed item-encoding operations (subprocesses of the item encoding process) at the same rate (performance accuracy being similarly high throughout), thus displaying like processing capacity; Sz participants, however, employed more subprocesses for item completions than did the MDD participants, who in turn used more subprocesses …

Are Text Messages A Feasible And Acceptable Way To Reach Female Entertainment Workers In Cambodia With Health Messages? A Cross-Sectional Phone Survey, Carinne M. Brody, Sukhmani Dhaliwal, Sovannary Tuot, Michael Johnson, Khuondyla Pal, Siyan Yi

Background: Despite great achievements in reducing the prevalence of HIV, eliminating new HIV infections remains a challenge in Cambodia. Entertainment venues such as restaurants, karaoke bars, beer gardens, cafes, pubs, and massage parlors are now considered important venues for HIV prevention efforts and other health outreach interventions.

Objective: The purpose of this study was to explore phone use and texting practices of female entertainment workers (FEWs) in order to determine if text messaging is a feasible and acceptable way to link FEWs to health services.

Methods: This cross-sectional phone survey was conducted in May 2015 with 97 …

Social Return On Investment: A Cost-Benefit Analysis Of The Hiv Integrated Care And Prevention Programs In Cambodia, Sovannary Tuot, Liza Tong, Sopheab Heng, Minh-Anh Luong, Khuondyla Pal, Pheak Chhoun, Siyan Yi

Background: KHANA’s HIV Integrated Care and Prevention (ICP) project provided comprehensive care and support to HIV-affected communities through home and community-based care teams from 2007 to 2011. The aim of this study was to use Social Return on Investment (SROI) methodology to evaluate the social, health, and economic impacts of the ICP project, enabling the calculation of a ratio cost-to-benefit for the community in terms of HIV care, support, and treatment. Methods: The SROI methodology is a social cost-benefit analysis framework that measures and accounts for the values created by a program or series of initiatives. Values were mapped to …

Promoting Healthy Eating And Physical Activity: A Qualitative Examination Of Community-Based Obesity Interventions In Rural Kentucky, Brooke F. Butterworth

Theses and Dissertations--Nutrition and Food Systems

Rural Americans are medically underserved groups and are at greater risk of becoming obese than urban Americans. The purpose of this qualitative study was to determine the perceived causes of obesity in six counties of rural Kentucky and to determine how to customize strategies to reduce obesity in these areas. University of Kentucky Cooperative Extension Service Agents formed coalitions in each of the six counties to assess their communities’ needs and assets to inform plans for implementing evidence-based obesity interventions. Between February and August of 2015, the coalitions were convened for a total of 11 meetings. Each of the coalition …

Perceived Stress, Caffeine Consumption, And Gpa Of Undergraduate Students At A Large Public University, Emma Simpson

Theses and Dissertations--Nutrition and Food Systems

Evidence suggests that college students may increase caffeine consumption to cope with the stress and demands of college. The relationships between perceived stress, caffeine consumption, and GPA were examined in students at a large public university. Students were surveyed to determine perceived stress (Cohen’s Perceived Stress Questionnaire), beliefs about caffeine, caffeine consumption, workload in and outside of the classroom, and GPA. Surveys were administered at the beginning of the semester and again at midterm. Based on Cohen’s 40-point scale, average stress scores increased from 15.95 ± 6.34 at the beginning of the semester to 18.89 ± 6.94 at midterms. Additionally, …

The Development And Implementation Of Hospital-Based Clinical Guidelines To Enhance Nursing Staff Efficacy In Glycemic Management At A Large Psychiatric Teaching Hospital, Cherno Bah

Doctor of Nursing Practice Projects

Background: This quality improvement project was conducted at the Colorado Mental Health Institute at Pueblo (CMHIP) in order to improve glycemic management. In psychiatric inpatient settings, proper glycemic management is inadequate which increases metabolic risk and poor patient outcomes. One way to address this problem is by using practice guidelines and education, which enhances nurses’ efficacy.

Purpose: The purpose of this project was to develop and implement a glycemic management guideline to enhance clinical nursing staff knowledge and confidence.

Method: Fifty-five clinical nursing staff attended an in-service and were asked to fill out a survey before and after the in-service …

January 2016, New England Osteopathic Heritage Center

New England Osteopathic Heritage Center Newsletter

Annual newsletter created by the New England Osteopathic Heritage Center in January 2016.

Saudi Scd Patients’ Symptoms And Quality Of Life Relative To The Number Of Ed Visits, Anwar E. Ahmed, Ahmed S. Alaskar, Donna K. Mcclish, Yosra Z. Ali, Mohammed H. Aldughither, Ahmad M. Al-Suliman, Hafiz M. Malhan

Biostatistics Publications

Background

Individuals living with sickle cell disease (SCD) have significantly increased emergency department (ED) use compared to the general population. In Saudi Arabia, health care is free for all individuals and therefore has no bearing on increased ED visits. However, little is known about the relationship between quality of life (QoL) and frequency of acute care utilization in this patient population.

Methods

A cross-sectional study was conducted on 366 patients with SCD who attended the outpatient department at King Fahad Hospital, Hofuf, Saudi Arabia. Data were collected through self-administered surveys, which included: demographics, SCD-related ED visits, clinical issues, and QoL …

Methods For Evaluating Respondent Attrition In Web-Based Surveys, Camille J. Hochheimer, Roy T. Sabo, Alex H. Krist, Teresa Day, John Cyrus, Steven H. Woolf

Biostatistics Publications

Background: Electronic surveys are convenient, cost effective, and increasingly popular tools for collecting information. While the online platform allows researchers to recruit and enroll more participants, there is an increased risk of participant dropout in Web-based research. Often, these dropout trends are simply reported, adjusted for, or ignored altogether.

Objective: To propose a conceptual framework that analyzes respondent attrition and demonstrates the utility of these methods with existing survey data.

Methods: First, we suggest visualization of attrition trends using bar charts and survival curves. Next, we propose a generalized linear mixed model (GLMM) to detect or confirm …

Proton Pump Inhibitors Are Associated With Increased Risk Of Development Of Chronic Kidney Disease, Pradeep Arora, Anu Gupta, Mojgan Golzy, Nilang Patel, Randolph L. Carter, Kabir Jalal, James W. Lohr

Biostatistics Publications

Background

Acute interstitial nephritis secondary to proton pump inhibitors (PPIs) frequently goes undiagnosed due to its subacute clinical presentation, which may later present as chronic kidney disease (CKD). We investigated the association of PPI use with the development of CKD and death.

Methods

Two separate retrospective case–control study designs were employed with a prospective logistic regression analysis of data to evaluate the association of development of CKD and death with PPI use. The population included 99,269 patients who were seen in primary care VISN2 clinics from 4/2001 until 4/2008. For evaluation of the CKD outcome, 22,807 with preexisting CKD at …

Improving Sensitivity Of Linear Regression-Based Cell Type-Specific Differential Expression Deconvolution With Per-Gene Vs. Global Significance Threshold, Edmund R. Glass, Mikhail G. Dozmorov

Biostatistics Publications

Background

The goal of many human disease-oriented studies is to detect molecular mechanisms different between healthy controls and patients. Yet, commonly used gene expression measurements from blood samples suffer from variability of cell composition. This variability hinders the detection of differentially expressed genes and is often ignored. Combined with cell counts, heterogeneous gene expression may provide deeper insights into the gene expression differences on the cell type-specific level.

Published computational methods use linear regression to estimate cell type-specific differential expression, and a global cutoff to judge significance, such as False Discovery Rate (FDR). Yet, they do not consider many artifacts …

African-American Patients With Cancer Talking About Clinical Trials (Tact) With Oncologists During Consultations: Evaluating The Efficacy Of Tailored Health Messages In A Randomised Controlled Trial—The Tact Study Protocol, R F. Brown, R Davis, M Wilson Genderson, S Grant, D Cadet, M Lessard, J Alpert, J Ward, G Ginder

Health Policy Publications

Introduction Low rates of accrual of African-American (AA) patients with cancer to therapeutic clinical trials (CTs) represent a serious and modifiable racial disparity in healthcare that impedes the development of promising cancer therapies. Suboptimal physician–patient consultation communication is a barrier to the accrual of patients with cancer of any race, but communication difficulties are compounded with AA patients. Providing tailored health messages (THM) to AA patients and their physician about CTs has the potential to improve communication, lower barriers to accrual and ameliorate health disparities.

Objective (1) Demonstrate the efficacy of THM to increase patient activation as measured by direct …

Dna Methylation Of Regulatory Regions Of Imprinted Genes At Birth And Its Relation To Infant Temperament, Bernard F. Fuemmeler, Chien-Ti Lee, Adelheid Soubry, Edwin S. Iversen, Zhiqing Huang, Amy P. Murtha, Joellen M. Schildkraut, Randy L. Jirtle, Susan K. Murphy, Cathrine Hoyo

Health Policy Publications

Background: DNA methylation of the differentially methylated regions (DMRs) of imprinted genes is relevant to neurodevelopment.

Methods: DNA methylation status of the DMRs of nine imprinted genes in umbilical cord blood leukocytes was analyzed in relation to infant behaviors and temperament (n = 158).

Results: MEG3 DMR levels were positively associated with internalizing (β = 0.15, P = 0.044) and surgency (β = 0.19, P = 0.018) behaviors, after adjusting for birth weight, gender, gestational age at birth, maternal age at delivery, race/ethnicity, education level, smoking status, parity, and a history of anxiety or depression. Higher methylation levels at the …

News Stories Of Intimate Partner Violence: An Experimental Examination Of Participant Sex, Perpetrator Sex, And Violence Severity On Seriousness, Sympathy, And Punishment Preferences, Matthew W. Savage, Jennifer A. Scarduzio, Kate Lockwood Harris, Kellie E. Carlyle, Sarah E. Sheff

Health Policy Publications

This study experimentally examines the effects of participant sex, perpetrator sex, and severity of violence on perceptions of intimate partner violence (IPV) seriousness, sympathy toward the victim, and punishment preferences for the perpetrator. Participants (N = 449) were randomly assigned to a condition, exposed to a composite news story, and then completed a survey. Ratings of seriousness of IPV for stories with male perpetrators were significantly higher than ratings of seriousness for stories with female perpetrators. Men had significantly higher sympathy for female victims in any condition than for male victims in the weak or strong severity of violence …

Gender Differences In Cardiometabolic Syndrome Among U.S. Rural And Non-Rural Adults, Srikanta Banerjee, Raymond Panas

2010-2016 Archived Posters

Cardiometabolic syndrome (CMS) places an individual at a higher risk of stroke and heart failure. The 2013 Behavior Risk Surveillance System survey, the largest national population-based survey, was used for logistic regression modeling. An effect-modifying relationship was found among women between rural residence and CMS.

The Difference Between Cacrep And Non-Cacrep Scores On Professional Counselor Licensure Examinations, Jason King

2010-2016 Archived Posters

This study compared a nine-year period of scores from the National Counselor Examination (NCE), the National Clinical Mental Health Counselor Examination (NCMHCE), and the state jurisprudence examination (SJE). with graduates (n=1,740) from a Council for Accreditation of Counseling and Related Educational Programs (CACREP) mental health counseling (MHC) specialization and with graduates (n=200) from a non-CACREP professional counseling specialization. Results from a t-test, Chi-Square, and Levene's test for equality of variances indicated a better performance from the non-CACREP graduates.

Comparative Analysis Of Eating Patterns Of Individuals With Obese Vs. Normal Bmi And With And Without Type 2 Diabetes, David A. Hernandez, Cheri Ann Hernandez, Chris M. Wellington, Arthur Kidd

2010-2016 Archived Posters

This study explored eating patterns of obese-weight (OB) and normal-weight (NW) individuals with and without Type 2 diabetes (T2D). The dietary intakes of OB-T2D individuals were significantly higher than those of NW individuals. Health care professionals can use this knowledge to provide direction for treatment modalities (e.g., different dietary strategies, more intensive dietary therapy, lifestyle counseling).

Healthy Weight Maintenance: A Narrative Analysis Of Weight Cycling In The Formerly Obese, Cheri Renee Lewis

2010-2016 Archived Posters

This study addressed weight cycling and sustained weight loss among 6 formerly obese weight cyclers. Self-determination theory (SDT) and social cognitive theory (SCT) provided theoretical frameworks. Findings revealed five overarching themes and that no single solution exists for successful sustained weight loss in this population.

Consensus Classifications Of Gross Motor, Manual Ability, And Communication Function Classification Systems Between Therapists And Parents Of Children With Cerebral Palsy., Doreen J Bartlett, Barbara Galuppi, Robert J Palisano, Sarah Westcott Mccoy

Physical Therapy Publications

No abstract provided.

Ua1c11/57 Sigma Theta Tau, Wku Nursing

WKU Administration Documents

Unidentified image of Sigma Theta Tau.

School-Based Dental Sealant Programs Prevent Cavities And Are Cost-Effective, Susan Griffin, Shillpa Naavaal, Christina Scherrer, Paul M. Griffin, Kate Harris, Sajal Chattopadhyay

Dental Public Health and Policy Publications

Untreated cavities can have far-reaching negative consequences for people's ability to eat, speak, and learn. By adolescence, 27 percent of low-income children in the United States will have untreated cavities. School-based sealant programs typically provide dental sealants (a protective coating that adheres to the surface of molars) at little or no cost to students attending schools in areas with low socioeconomic status. These programs have been shown to increase the number of students receiving sealants and to prevent cavities. We analyzed the cost-effectiveness of school sealant programs using data (from school programs in fourteen states between 2013 and 2014) on …

Providing Hands-On Training With Bioinformatics Databases: A Collaboration Between Vcu Libraries & Wright Center For Clinical And Translational Research, Karen H. Gau, Julie A. Arendt, Amy Olex, Aaron R. Wolen

VCU Libraries Faculty and Staff Presentations

Background
With the goal of increasing specialized services for researchers, Virginia Commonwealth University (VCU) Libraries sent its basic science librarians to an intensive training on bioinformatics databases, “A Librarian’s Guide to NCBI.” VCU’s Wright Center for Clinical and Translational Research (Wright CCTR) was expanding the educational component of its bioinformatics support around the same time. This year, the librarians partnered with the Wright CCTR to offer an introductory bioinformatics database workshop introducing researchers to genetic/genomic databases.

Methods
For one week in June, sessions were conducted introducing up to 30 faculty and staff to The Cancer Genome Atlas and NCBI’s Gene, …

The Individual Day-To-Day Process Of Social Anxiety In Vulnerable College Students, Cynthia G. Campbell, Karen L. Bierman, Peter C. M. Molenaar

Psychological Sciences Faculty Publications and Presentations

Transitions requiring the creation of new social networks may be challenging for individuals vulnerable to social anxiety, which may hinder successful adjustment. Using person-specific methodology, this study examined social anxiety in vulnerable university freshman away from home during their first semester of college to understand how day-to-day processes of social anxiety influenced future social anxiety and social withdrawal. Participants completed daily measures of four components of social anxiety which were examined as a process during a single day, and as a process affecting social anxiety and social withdrawal the next day. For most individuals, same day fear of negative evaluation …

The Semantic Memory Imaging In Late Life Pilot Study, Michael Adam Sugarman

Wayne State University Dissertations

Introduction: Several functional magnetic resonance imaging (fMRI) studies have analyzed the famous name discrimination task (FNDT), an uncontrolled semantic memory probe requiring discrimination between famous and unfamiliar individuals. Completion of this simple task recruits a semantic memory network that has shown utility in determining risk for Alzheimer's disease (AD). Specific semantic memory probes using biographical information associated with famous individuals may build on previous findings and yield superior information regarding risk for AD.

Method: Sixteen cognitively intact elders completed the FNDT and two novel tasks during fMRI: Categories (matching famous individuals to occupational categories) and Attributes (matching famous individuals to …

Bilingualism Across The Adult Life-Span: Age And Language Usage Are Continuous Variables, Sara Incera Burkert

ETD Archive

The purpose of this dissertation research was to analyze the effects of bilingualism and age on cognitive function. Specifically, I investigated the impact of bilingualism and age on two measures of executive control. The Stroop task is a measure of response inhibition, and the Flanker task is a measure of attention selection. Participants responded using a computer mouse. The mouse-tracking paradigm allowed me to examine the continuous dynamics of the responses as participants completed each trial. A better understanding of the impact of bilingualism and age on cognitive function has the potential to minimize cognitive decline in older age. The …

Development Of A Testicular Cancer Vaccine, Roberto Aguilar Iii

ETD Archive

Testicular cancer mainly affects men between the ages of 20 and 35 but is the most common male neoplasm between the ages of 15 and 34. The National Cancer Institute (NCI) states that localized testicular cancer has a recurrence rate of 15-20% and tumors that are Sertoli or Leydig cell derived fail to respond to chemotherapy or radiation treatments. The recurrence rate may increase to 32% if at diagnosis the tumor is greater than 4 cm in size with invasion of the rete testes. To improve therapy for testicular cancer, we examined the usefulness of a testicular cancer vaccine. We …

Student Perceptions Of Faculty's Social Presence In Online Health Science Courses, Samantha J. Mencini

ETD Archive

With continued surges in enrollment in the various online health science programs, especially nursing programs, there is a great need for additional research to be conducted regarding how students perceive their professors social presence in an online learning environment through the use of Computer-Mediated Communications - CMCs. The objectives of this descriptive phenomenological qualitative study were to: 1) illustrate how students perceive their professors’ social presence as used in various types of CMCs; 2) identify emotions which the students have experienced in response to their professor’s CMCs; 3) unveil common themes regarding student perception of their professors’ social presence; and …

The Voice And Cystic Fibrosis: A Descriptive Case Study, Veronica Smitley

ETD Archive

Cystic fibrosis is a common autosomal recessive disease with severe effects on the respiratory, digestive, and endocrine systems. Symptoms include chronic cough and wheezing, frequent upper respiratory tract infections, and reflux disease. While most treatments for cystic fibrosis aim to mitigate the respiratory and gastrointestinal dysfunction, the potential adverse effects on an individual’s voice has not been researched in a systematic manner. We hypothesized that individuals with cystic fibrosis may show physical signs of vocal fold damage, as well as common dysphonic symptoms. Given the impact voice disorders have an overall quality of life, identification and management of cystic fibrosis-related …

A Survey Of Speech Sound Production In Children With Visual Impairment, Shannon L. Zeszut

ETD Archive

Few studies have explored the characteristics of speech sound productions in children with visual impairments. Similarly, there is little research on how speech- language pathologists provide therapy to improve speech sound productions in children with visual impairments. This study addressed the need for research evidence upon which speech-language pathologists might base their clinical practices. The intent of this report is to contribute to the available information on successful speech-language therapy for speech sound productions in children with visual impairments.

Fifteen speech-language pathologists responded to a survey that inquired about speech sound productions in the children with visual impairments on their …

Southeastern Alumni Magazine- Winter 2016, Southeastern University - Lakeland

Southeastern Alumni Magazine

Dr. Aimee Franklin '07 returned to Southeastern in 2014 as an assistant professor of biology. Prior to returning, she earned her Ph.D. in Neuroscience at the University of Alabama Birmingham where she studied Fragile X Syndrome, the leading known genetic cause for autism. One of her articles published in Biological Psychology was one of the most cited articles in that journal in 2014.