Medicine and Health Sciences Commons^™

A Case Study Of Cochlear Implants And Complications, Carly E. Amurao

Senior Honors Projects

A cochlear implant is an electronic medical device that replaces the function of the damaged inner ear, allowing the individual access to sound. In recent years, there has been tremendous progress in developing technology in the area of cochlear implants to aid those with severe/profound hearing loss. Specifically, there has been a movement towards bilateral implantation. Each cochlear implant candidate has a unique hearing loss, and must reach required bench marks in order to be considered a viable candidate for a cochlear implant. This process includes: meeting the required level of hearing loss, a required trial with hearing aids that …

The Complicated Process Of Disenfranchised Grief While In College, Daniella Markowski

Senior Honors Projects

In order to demonstrate the importance of understanding and recognizing grief, this research project explores the capacity for young adults within the college setting to experience two negative grief processes: disenfranchised and complicated grieving. In broad terms, disenfranchised grief occurs when society does not recognize the grief a bereaved person is experiencing; complicated grief occurs when the bereaved continues to grieve for a prolonged period of time in which they are unable to adapt to their life. While it can be difficult to define a specific population who is at risk for experiencing these types of grief, society often fails …

Legal, Structural, And Ethical Barriers To Prevention And Treatment Of Hiv/Aids: A Review Of Malaysia And Kazakhstan, Amanda S. Volk

Public Health Undergraduate Program

The HIV/AIDS epidemic in nations that use Islamic scripture in law has faced several challenges. The conservative ethical and political approach to the epidemic has been ineffective in halting the spread of and treating the existence of HIV/AIDS. It is expected that there will be several structural barriers to obtaining care, treatment, and prevention services for HIV/AIDS in these nations particularly for vulnerable populations such as Men who have Sex with Men (MSM), People Who Inject Drugs (PWID), and sex workers. This research will investigate and analyze research, laws, politics, ethics, and structure in the nations of Malaysia and Kazakhstan …

Turkey: An Overview On National Drug Use, Treatment Design, And The Characteristics Of Patients Utilizing Treatments, Katherine Waye

Public Health Undergraduate Program

Existing research on the patterns and risk factors of drug use and how they vary by age and location in Turkey is limited. The paper will examine the drug treatment options within Turkey as well as the socio-demographic characteristics, behaviors, treatment history, and identified correlates of lifetime and current injection drug use of Turkish citizens who were admitted to inpatient substance use treatment at public and private facilities in Turkey during 2012 and 2013. Of the 11,247 patients at the 22 public treatment centers in 2012-2013, a majority were male, lived with family, were unemployed, and had an average age …

Breastfeeding Rates In Marshallese Mothers; A Needs Assessment, Olivia N. Pennington

The Eleanor Mann School of Nursing Undergraduate Honors Theses

ABSTRACT

Background. Multiple health disparities are associated with the Marshallese population in Northwest Arkansas. Childhood obesity, linked to a decrease in exclusive breastfeeding, is one of the predominant issues. Since their migration to the United States, exclusive breastfeeding rates of Marshallese mothers have steadily declined throughout the years. Little research has been conducted to help combat this growing health disparity. Due to the increased growth in this population in Northwest Arkansas, it is imperative that measures are taken to decrease these disparities to improve the overall health of the future generations.

Objective: To determine the relationship between maternal age, …

Oncolog, Volume 61, Number 05, May 2016, Bryan Tutt, Katelyn Werner

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Intratumoral Therapies Offer Novel Cancer Treatment Approach: Injecting cancer treatments such as vaccines and genetically modified bacteria and viruses directly into tumors may shrink or destroy the tumors and stimulate an immune response that attacks tumor cells. These treatments have shown promise in clinical trials, and newer trials are exploring whether such treatments can augment the effectiveness of immunotherapy in patients with metastatic or inoperable disease.
• High-Risk Acute Lymphoblastic Leukemia Subtype Targeted in Upcoming Clinical Trial: Early T cell precursor acute lymphoblastic leukemia (ETP-ALL), an uncommon subtype of T cell acute lymphoblastic leukemia (T-ALL), carries a poor prognosis and low …

Is Cell Viability Always Directly Related To Corrosion Resistance Of Stainless Steels?, E. Salahinejad, M. Ghaffari, Daryoosh Vashaee, Lobat Tayebi

School of Dentistry Faculty Research and Publications

It has been frequently reported that cell viability on stainless steels is improved by increasing their corrosion resistance. The question that arises is whether human cell viability is always directly related to corrosion resistance in these biostable alloys. In this work, the microstructure and in vitro corrosion behavior of a new class of medical-grade stainless steels were correlated with adult human mesenchymal stem cell viability. The samples were produced by a powder metallurgy route, consisting of mechanical alloying and liquid-phase sintering with a sintering aid of a eutectic Mn–Si alloy at 1050 °C for 30 and 60 min, leading to …

Viruses, Vaccines And The Public, Judy Diamond, Julia Mcquillan, Amy Spiegel, Patricia Wonch Hill, Rebecca Smith, John T. West, Charles Wood

World of Viruses

Current research in virology is changing public conceptions about vaccines and infectious disease. The University of Nebraska State Museum collaborated with research virologists, science writers, artists and learning researchers to create public outreach materials about viruses and infectious disease. The project, funded by the National Institute of Health’s SEPA program, developed comics, a book with Carl Zimmer, and other materials and programs. The project launched three kinds of learning research: 1) a survey of Nebraska adults on their opinions about vaccines and infectious disease; 2) a study comparing the mental models of viruses, vaccines and infection from virologists, teachers, and …

Upregulation Of Antibiotic Activity Of A Streptomyces Sp. Via Co-Cultures With Challenge Pathogens, Anne A. Sung

Honors Scholar Theses

Marine natural product drug discovery has begun to play an important role in the treatment of diseases. Early drug discovery from natural products came primarily from plants, but after the discovery and development of penicillin, scientists started looking at natural products from microorganisms. Numerous natural products have been discovered from members of the order Actinomycetales, particularly in the genus Streptomyces, due to their metabolic diversity in the production of biologically active secondary metabolites. Ascidians, also known as tunicates, are marine invertebrates that contain many host-associated microbes. Adult tunicates are sessile, which makes them vulnerable to predators, and thus, they …

The Potentiating Effects Of Acetaminophen On Oxidant Air Pollutant Sensory Irritation And The Onset Of Asthma, Bennett J. Doughty

Honors Scholar Theses

Through its toxic metabolites, acetaminophen can cause oxidative injury in the liver. This damage has not yet been investigated in the respiratory tract. If acetaminophen also causes oxidative stress and injury here, this widely used antipyretic could potentiate the adverse effects of oxidant air pollutants. Thus, the primary goal of this project is to determine if low non-hepatotoxic doses of APAP is correlated with an increase of oxidative stress in the airways, possibly linking APAP to the onset of asthma. Using data that reflected murine breathing patterns, the addition of acetaminophen greatly increased the reflex irritant response to ETS through …

Evaluating Dietary Quality And Taste Preferences With A Simple Liking Survey: Application To Studying Individuals With Morbid Obesity, Marina L. Zoghbi

Honors Scholar Theses

Feasible ways are needed to screen for dietary behaviors and taste preferences in clinical settings. We examined the internal validity and reliability of a brief survey to assess food preferences and dietary behaviors among morbidly obese individuals considering bariatric surgery. Survey-reported liking is a proxy for dietary intake, correlating with reported food intake and biomarkers of nutritional status (Sharafi et al, 2015) and linking taste genetics with diet and health (Pallister et al, 2015). Methods –Enrolled were 138 morbidly obese patients awaiting bariatric surgery, who completed a 100-item liking survey of foods/beverages, physical/sedentary activities, and pleasurable/unpleasurable experiences. They were oriented …

Early Hearing Loss And Language Outcomes: A Review And Case Study, Sarah Reid

Honors Scholar Theses

Early hearing loss is a widespread medical and developmental concern that affects over 1 in 500 infants (Mehl, 1998). Hearing impairments in children have been linked to a variety of adverse developmental outcomes, including poor speech and language ability and difficulties with cognition and social-emotional adjustment. Early intervention has been demonstrated to be one of the most important factors in influencing outcomes for children born with congenital hearing loss (Vohr et al., 2008). This review and case study aims to outline the connection between early hearing loss, intervention, and speech/language abilities by exploring the case of a 13-month-old infant with …

Pituitary Adenylate Cyclase-Activating Polypeptide Orchestrates Neuronal Regulation Of The Astrocytic Glutamate-Releasing Mechanism System XC−, Linghai Kong, Rebecca Albano, Aric Madayag, Nicholas Raddatz, John R. Mantsch, Sujean Choi, Doug Lobner, David A. Baker

Biomedical Sciences Faculty Research and Publications

Glutamate signaling is achieved by an elaborate network involving neurons and astrocytes. Hence, it is critical to better understand how neurons and astrocytes interact to coordinate the cellular regulation of glutamate signaling. In these studies, we used rat cortical cell cultures to examine whether neurons or releasable neuronal factors were capable of regulating system x_c^-(Sxc), a glutamate-releasing mechanism that is expressed primarily by astrocytes and has been shown to regulate synaptic transmission. We found that astrocytes cultured with neurons or exposed to neuronal-conditioned media displayed significantly higher levels of Sxc activity. Next, we demonstrated that the pituitary …

The Effect Of Interspecies Signaling On Stenotrophomonas Maltophilia Growth., Zachary Ethan Dickinson

College of Arts & Sciences Senior Theses

Cystic fibrosis (CF) is a genetic disorder that effects over 70,000 people worldwide, and is particularly prevalent in those of Caucasian descent. CF increases susceptibility to chronic infections of the lungs and GI tract, often leading to decreased quality of life and early death to afflicted individuals. No cure is available, and so treatment is limited to treating the frequent infections that afflict CF patients. Several species of bacteria are commonly implicated in these infections, including Stenotrophomonas maltophilia. Infections of this species is of particular interest as it has been shown to be highly antibiotic resistant. This is a concern …

The Effect Of Grief On Bonding With A Deaf Child, Gabriela Cardona

Senior Honors Projects

Since hearing screenings for children happen after birth, there is no way for

parents to prepare themselves for having a child with hearing loss and any

lifestyle changes that will follow. Many parents have trouble coping with and

accepting the news of having a deaf or hard-of-hearing child. This diagnosis also

often brings along with it the stress of additional necessary appointments and

decisions. The parent’s idea of a “perfect and ideal” child is gone. Parents need

to grieve the loss of this idea while also tending to their child and giving their

child the opportunities and support needed for …

Effective Coping Mechanisms For Nurses Following Patient Death, Tiffany Gagliardo

Senior Honors Projects

The loss of a loved one affects family and friends but also the nurses and health care providers. At the time of death, nurses are at the bedside providing comfort and words of support. But who is there to support the nurses when the patient dies? The objective of this research project is to identify positive coping mechanisms that nurses can use on a daily basis through an extensive analysis of the literature and individual nurse interviews.

Unfortunately, patient death may be more common for nurses who work on Intensive Care Units (ICU) and Hospice agencies. With the daily requirements …

Stepped Care Versus Standard Trauma‐Focused Cognitive Behavioral Therapy For Young Children, Alison Salloum, Wei Wang, John Robst, Tanya K. Murphy, Michael S. Scheeringa, Judith A. Cohen, Eric A. Storch

Social Work Faculty Publications

Background

To compare the effectiveness and cost of stepped care trauma‐focused cognitive behavioral therapy (SC‐TF‐CBT), a new service delivery method designed to address treatment barriers, to standard TF‐CBT among young children who were experiencing posttraumatic stress symptoms (PTSS).

Methods

A total of 53 children (ages 3–7 years) who were experiencing PTSS were randomly assigned (2:1) to receive SC‐TF‐CBT or TF‐CBT. Assessments by a blinded evaluator occurred at screening/baseline, after Step One for SC‐TF‐CBT, posttreatment, and 3‐month follow‐up. Trial registration: ClinicalTrials.gov: https://www.clinicaltrials.gov/ct2/show/NCT01603563.

Results

There were comparable improvements over time in PTSS and secondary outcomes in both conditions. Noninferiority of SC‐TF‐CBT …

Formative Research For Case Management Protocol Addressing Neighborhood Trauma Due To Violence, Azada Wan

Renée Crown University Honors Thesis Projects - All

My capstone project is focused on conducting formative research for developing a case management protocol to reduce recidivism in youths aged 13 to 16. This formative research will serve as a basis for Street Addiction Institute Inc.’s request for proposal (RFP) to Onondaga County Department of Justice. As Street Addiction Institute Inc. is currently in the process of applying for funding at the federal and county levels, the formative research I conducted by integrating knowledge obtained from literature, expertise of community leaders and professionals, and understanding of youth’s specific characteristics, needs, and risks, will inform the development of a case …

Dental Health Education Outreach In Syracuse New York, Alyson Forman

Renée Crown University Honors Thesis Projects - All

Oral health is a commonly neglected area of healthcare across the world. Especially amongst underserved populations, many people do not prioritize dental health care, do not have access to dental health care, and do not realize the importance of dental health care. This project aims to educate the population on the importance of dental health care. The participants in the project include those enrolled in different parenting programs at a local non-profit organization in Central New York. Pre and post surveys were administered to evaluate an increase in knowledge on dental health. Demographic-specific educational materials such as brochures, pamphlets, games, …

Childhood Psychosocial Determinants Of Cardiovascular Health, Samuel S. Gidding, Erica D. Sood

Department of Medicine Faculty Papers

Understanding risk and protective factors that impact cardiovascular health is of utmost importance. There is ample evidence that cardiovascular health begins in childhood, tracks over time, and is subject to adverse social influences. This paper reviews key studies examining the relations of psychosocial factors in childhood to cardiovascular health in adulthood. The existing literature provides evidence for both individual and cumulative effects of childhood psychosocial factors on adult cardiovascular health across the population, although the specific mechanisms underlying these relationships are not yet fully understood. This paper also includes a discussion of evidence-based strategies for prevention and treatment of childhood …

Association Of Ecological Factors With Rift Valley Fever Occurrence And Mapping Of Risk Zones In Kenya, Gladys Mosomtai, Magnus Evander, Per Sandström, Clas Ahlm, Rosemary Sang, Osama Ahmed Hassan, Hippolyte Affognon, Tobias Landmann

All Peer-Reviewed Publications

Objective: Rift Valley fever (RVF) is a mosquito-borne infection with great impact on animal and human health. The objectives of this study were to identify ecological factors that explain the risk of RVF outbreaks in eastern and central Kenya and to produce a spatially explicit risk map. Methods: The sensitivity of seven selected ecological variables to RVF occurrence was assessed by generalized linear modelling (GLM). Vegetation seasonality variables (from normalized difference vegetation index (NDVI) data) and 'evapotranspiration' (ET) (metrics) were obtained from 0.25-1 km MODIS satellite data observations; 'livestock density' (N/km2), 'elevation' (m), and 'soil ratio' (fraction of all significant …

Hospitalized Patients At High Risk For Obstructive Sleep Apnea Have More Rapid Response System Events And Intervention Is Associated With Reduced Events., Sunil Sharma, Md, Anindita Chowdhury, Lili Tang, Leslee Willes, Brian Glynn, Stuart F Quan

Department of Medicine Faculty Papers

BACKGROUND: Rapid response system (RRS) is a safety tool designed for early detection and intervention of a deteriorating patient on the general floor in the hospital. Obstructive sleep apnea (OSA) has been associated with significant cardiovascular complications. We hypothesized that patients with high-risk of OSA have higher rate of RRS events and intervention with positive airway pressure therapy in these patients can mitigate the RRS events.

METHODS: As part of a clinical pathway, during a 15 month period, patients with BMI ≥ 30 kg/m2 in select medical services were screened with a validated sleep questionnaire. Patients were characterized as high …

Estrogen's Effects On Oxidative Stress Levels In Glial Cells, Jacob J. Dirkman

Theses and Dissertations

A decrease in astrocyte function and viability has been linked to many neurodegenerative diseases, including schizophrenia, major depressive disorders, Alzheimer’s disease, and Amyotrophic Lateral Sclerosis (ALS). Previous research indicates that some estrogens may have a positive effect on neuron and astrocyte viability. Estrogens’ effects on the brain are of interest as estrogens are commonly prescribed as hormone replacement therapy to reduce the symptoms of menopause in women. Unfortunately, these effects on are not completely understood. The goal of the project was to discover if estrogen has any protective effect on astrocytes exposed to oxidative stress. We measured the oxidative stress …

Importance And Implementation Of Exercise Programs In The Geriatric Population, Denise Grezeszak

Honors Projects

No abstract provided.

Parent Beliefs About Technology: A Comparison Of Homeschool And Formal Education Families, Eli L. Skelton

Rehabilitation, Human Resources and Communication Disorders Undergraduate Honors Theses

The purpose of this study was to gain information about how technology is used by parents to assist school learning as well as their opinions and beliefs about the role of technology in the learning process. Specifically, using homeschool and educational networks as well as social media for distribution of a digital questionnaire, this study sought to gauge parents’ experience with, as well as responses to, attitudes, and values towards the use of technology in homeschool and classroom education. Sixty-five parents of children who are studying at the elementary grade levels participated in this study. Twenty of these were parents …

Toddlers And Technology: An Examination Of How The Digital Surround May Be Related To Prototypic Vocabulary Development And Social Interactions During Play, Hannah Biarnesen Hutcheson

Graduate Theses and Dissertations

This study sought to examine how the digital technology that surrounds young children may be related to prototypic vocabulary development and Social interactions during play. Twenty-six families in the Northwest Arkansas region with children between 15-36 months of age participated in the study. Thirteen children attended a campus preschool, six children attended a grant-funded local preschool, and seven children, all from the Northwest Arkansas area, were part of an earlier home-based study. The materials for the study included a developmental-technology use questionnaire and the MacArthur-Bates Communicative Development Inventories. Archival videotaped play sessions with the seven home-based children utilized a “Little …

Effects Of Talker Variability On Spectral Contrast Effects., Asim Mohiuddin

College of Arts & Sciences Senior Theses

Spectral contrast effects are context-dependent effects that influence the way we perceive certain sounds. Evidence of these effects can be seen in experiments where a precursor sound (e.g. a sentence) is followed by a target vowel sound (like /ɪ/ as in "bit" or /ɛ/ as in "bet"). If the precursor's frequency was emphasized in areas more consistent with the frequency of /ɛ/, listeners tend to perceive the target sound to be the opposite i.e. /ɪ/. A recent study shows using sentence precursors from 200 different talkers diminishes these effects questioning previous claims that talker variability has no influence on spectral …

Comparing The Quantitation Of Opiates From Possible Drug Overdose Cases Using Results Of Blood Analysis And Liver Analysis, Lee Ann Garozzo

Forensic Science Theses

Currently the quantitation of opiates at the Erie County Medical Examiner’s Office Toxicology Laboratory is conducted through whole blood analysis. The objective of this thesis project was to determine if the analysis of opiates could be conducted through liver analysis, and if the analysis of opiates would provide a more accurate quantitation compared to the blood analysis. The quantitation of opiates was conducted from the livers of sixty-four possible overdose cases that were brought into the Erie County Medical Examiner’s Office between 2013 and 2015. Results showed that the opiate drugs could successfully be quantitated using the liver analysis. Generally …

Flight Physician - May, 2016, Civil Aviation Medical Association

Browse all Civil Aviation Medical Association Newsletters

A nineteen page newsletter of the Civil Aviation Medical Association. The newsletter provided news about civil aviation medicine and information related to the organization.

Fosces: Adding Another Library Tile To The Medical School Mosaic, Alexandra Gomes, Thomas Harrod

Himmelfarb Library Faculty Posters and Presentations

The 2014 launch of the revised medical school curriculum provided new opportunities for librarians to collaborate with faculty. Due to past informatics instruction in the first year curriculum, we were invited to expand this content as part of a new formative Objective Structured Clinical Examination (FOSCE) initiative. This poster will describe the development and implementation of the FOSCE informatics curriculum.

In FOSCEs, small groups of students rotated through simulated patient encounters in order to demonstrate their clinical knowledge and skills. Due to simulation center logistics, students alternated between skills demonstration and informatics activities. The informatics component consisted of fifty minute …