The Effect Of The Cyp1a2 -163 C>A Polymorphism On The Metabolism Of Caffeine And Effect On Performance, Gabrielle E. Giersch

Masters Theses, 2010-2019

Prior studies from our laboratory suggest that the -163 C > A polymorphism of the Cytochrome P450 (CYP1A2) gene influences the ergogenic effect of caffeine. Although this polymorphism has been known to influence the inducibility of hepatic CYP1A2 and the rate of caffeine metabolism, levels of caffeine and/or metabolites have never been reported in these aforementioned studies (1, 12, 16). Thus, a mechanistic link between the polymorphism and the ergogenic effect of caffeine is lacking. The purpose of this study was to determine if the CYP1A2 polymorphism affected caffeine metabolism between the genotypes (AA homozygotes and C allele carriers). Twenty male …

Untitled, Dianna Silvagni

be Still

Art is a very personal statement. When viewing art I look for pieces to which I can relate and enjoy, whether they are realistic or abstract. When I create a piece of art it is my personal observations, experiences and spiritual connection to the piece that helps me create it. After many years of working in charcoal, chalk pastels and acrylics, mostly creating art centered around the female form, I decided to try sculpting in clay. I found the experience to be really challenging, but enjoyable.

This piece is an attempt to bring many pieces of my life with my …

Want To Lose Weight? Commercial Weight Loss Programs Vs. Primary Care, Jessica Jacobson, Katherine Chui

Physician Assistant Capstones, 2016 to 2019

Context Overweight and obesity rates are on a continuous incline in the United States leading to increased rates of diabetes, cardiovascular disease and death. Much of the healthcare costs are going into treating this disease; therefore, it is vital to find effective weight loss treatments in both the primary care and community settings to reduce the prevalence of overweight and obesity and subsequent healthcare costs.

Objective To assess whether primary care-based therapy or commercial weight loss programs help overweight and obese patients lose 5% of their weight from baseline.

Design, Setting and Participants A systematic review of four randomized control …

Patient Satisfaction As A Reflection Of Quality Health Care And Outcomes, Ian C. Brown, Taylor M. Piatkowski

Physician Assistant Capstones, 2016 to 2019

Background: In 2006 the Centers of Medicaid and Medicare Services mandated that acute care centers begin submitting HCAHPS survey data for financial reimbursement for Medicare patients. The national shift to a patient centered focus and the financial incentive to improve patient satisfaction scores has stimulated debate regarding the relationship between patient satisfaction and quality healthcare.

Clinical Question: Does improvement in patient satisfaction with their healthcare and its providers, as measured by the HCAHPS survey, improve healthcare quality and outcomes?

Design: Systematic literature review.

Methods: Searches were performed using PubMed and Scopus databases.The terms used for the PubMed search were “patient …

Case Study: Provider For Program To Prevent The Revictimization Of Persons Trafficked For Sex, Janis G. Arlow

Masters Theses, 2010-2019

This case study seeks to identify behavior, skills, and attitudes of a professional providing an effective reintegration program for persons trafficked for sex. New demands on medical and social services were created over the past two decades by legislative changes. Initial research focuses on rescue and unmet primary needs. The service program selected for this study has stepped beyond awareness and rescue efforts to the rehabilitation and prevention of revictimization of trafficked persons. A literature review covers the history of sex trafficking in the United States; the recovery environment; materials, trainings and programs available for professionals seeking knowledge to serve …

Athletic Trainers' Or Athletic Training Students' Perceptions Of Sexual Harassment By Student-Athletes In The Collegiate Setting, Amber M. Simmons

Masters Theses, 2010-2019

Sexual harassment is an issue that occurs in healthcare professions and on college campuses nationwide. Athletic trainers employed at the collegiate setting are healthcare professionals who work in close conjunction with student-athletes, which may predispose a risk of a sexual harassment occurrence. A study was conducted to investigate the sexual harassment of athletic trainers and athletic training students by student athletes at the collegiate setting. A Qualtrics survey, containing closed- and open-ended questions, was sent out to 297 CAATE-accredited athletic training program directors; the athletic training staff at these institutions were also sent the survey as well. The program directors …

An Appointment With Dr. Joseph Dejarnette: An Analysis Of A Leading Eugenics Advocate And How His Legacy Has Been Rewritten, 1906-1943, Brianna Melchione

Masters Theses, 2010-2019

The following is a thesis containing two separate parts: the background paper and a website. While both parts have been created with the ability to stand alone, they work best in conjunction with one another. The overall project provides a close study of Staunton, Virginia’s Western State Hospital’s Superintendent, Dr. Joseph DeJarnette, who practiced there from 1906-1943, and his involvement with eugenic sterilization. Dr. DeJarnette practiced during the Progressive Era, which influenced him to be a man desiring reform and progress, through science. The goal of this project is to analyze how his reputation as a doctor has been rewritten …

CañAda De La Carpenteria - Diseños, Glo No. 243, Monterey County, And Associated Historical Documents.

Individual Ranchos in Monterey and SLO Counties

Diseños - Hand-drawn Spanish-Mexican map demonstrating the physical boundaries of land granted to Mexican citizens by the Spanish or Mexican.

Expediente – Hand-written Spanish-Mexican land grant document issued to Mexican citizens in Alta California for land in Alta-California.

Work Progress Administration Abstract (WPA Abstract) – A summary document prepared in 1938 under the Work Progress Administration program detailing the history of a rancho beginning with the Spanish-American land through the U.S. patenting process.

Hornbeck Rancho Detail Sheet (AKA Detail Sheet) – A summary sheet generated from a land patent database that details the history of a rancho, along with the …

A Coach's Guide For Injury Prevention In Youth Football, William Edward Allen Iii

Senior Theses

Youth football is a declining sport this day in age, and this decline can be associated with the negative connotations on football portrayed by the media. Parents need a sense of security when it comes to the health of their children, and this can be achieved by creating a safer environment; one in which young athletes correctly learn safe techniques improving the quality of the game, leading to a decrease in injuries. By creating a website that details instructions and provides protocols to educate coaches on proper preventative injury practices, football can take a step forward in injury prevention, resulting …

The Fourth Color, April Emily Drafts-Johnson

Senior Theses

This thesis centers around short stories based on the student's favorite author, David Sedaris. Sedaris is a modern humor essayist who uses experiences from his daily life to create vivid, “real-ish” stories to entertain his readers. In nursing and in life, there are interesting tales to be told. The following stories are imaginative events that are based on the author’s personal experiences. Stories about family, coming of age, reflections on life, and fictional recounts of time spent working odd jobs in the hospital are all divided into five themes—the human experience, making the best of it, loss, darkness, and light. …

A Comparison Of Health Care Systems In The Western World, Katherine Regan Lawall

Senior Theses

This senior thesis evaluates the health care systems of the Netherlands, Belgium, Switzerland, and Denmark, before looking at how their approaches could be adapted to the U.S. system. I picked these specific countries due to their similarity in geographic location, demographic, religious affiliations, and population size but have different styles of health care systems (public, mixed, and private) that are set up in varying ways. Additionally, these populations have similar health issues to one another, such as aging-populations, and to the U.S. as well like the top causes of death. However, these four western European countries have longer life expediencies …

Implementation And Evaluation Of A Social Media Campaign To Promote Cervical Cancer Prevention And Control, Kelsie Nicole Dirksing

Senior Theses

Background: Cervical Cancer-Free South Carolina (CCFSC) is a member state of the Cervical Cancer-Free Coalition focused on eliminating cervical cancer through screening, follow-up care, HPV vaccination, and education. CCFSC utilizes social media to help spread awareness about cervical cancer prevention and control.

Purpose: The purpose of this thesis was to develop, implement, and evaluate a social media campaign for CCFSC during Cervical Health Awareness Month in January 2016.

Methods: Two social media plans – one for CCFSC use and another for CCFSC partner use – were developed for use during Cervical Health Awareness Month in January 2016. The CCFSC posts …

Orthotopic Heart Transplant Following Implantation Of A Systemic Ventricular Assist Device In A Patient With Congenitally Corrected Transposition Of The Great Arteries And Dextrocardia Situs Inversus Totalis, Bree Ann C. Young, Zachariah B. Nealy, Michael F. Mcgrath, John M. Herre

The VAD Journal

Congenitally corrected transposition of the great arteries (CCTGA) is a rare congenital heart disease that commonly results in congestive heart failure due to exposure of the anatomic right ventricle to systemic pressures. Additional anatomic abnormalities, such as situs inversus, in which the viscera are mirror images of normal anatomy, or dextrocardia in which the heart apex is located on the patient’s right, once were contraindications to transplant in the treatment of advanced heart failure. However, recent advancements now allow for the management of heart failure through mechanical circulatory support and subsequent transplant. This case presents a 52 year-old man with …

Morality And The Extra-Medical Use Of Drugs, Jerry Schik O.S.C.

Obsculta

Nota bene - The following is one of three major papers written forty-five years ago as a requirement for the Master of Arts in Theology degree. The author has revisited the topic in an addendum attached to this article to consider how the moral theologian can view extra-medical marijuana use in the twenty-first century. Originally written in 1971 at http://digitalcommons.csbsju.edu/sot_papers/594/

Optimal Time Between Procedures For Contralateral Total Knee Arthroplasty, Thomas G. Wilson

Nursing Capstones

No abstract provided.

Case Report: The Effect Of Yoga In Adults With Hypertension, Kristen Bowe

Nursing Capstones

No abstract provided.

Amyloidosis Masquerading As Suspected Angioedema: Delay In Diagnosis, Grace Berlin Do, Marie S. O’Brien Do

Department of Medicine

No abstract provided.

Intermittent Recurrent Renal Failure: Diagnosing Atypical Hemolytic Uremic Syndrome, Shannon Davis Do, Philip Dunn Do, Robert Schreiner Do

Department of Medicine

No abstract provided.

Germline Defects Caused By Smed-Boule Rna-Interference Reveal That Egg Capsule Deposition Occurs Independently Of Fertilization, Ovulation, Mating, Or The Presence Of Gametes In Planarian Flatworms, Jessica Kathryne Steiner, Junichi Tasaki, Labib Rouhana

Biological Sciences Faculty Publications

Few animals are known to lay eggs in the absence of ovulation or copulation, as it is presumably energetically wasteful and subjected to negative selection. Characterization of Smed-boule, a member of the DAZ family of germline RNA-binding proteins, revealed that egg capsule (or capsule) production and deposition occurs independently of the presence of gametes in the planarian flatworm Schmidtea mediterranea. Reduction of Smed-boule expression by RNA-interference (RNAi) causes ablation of spermatogonial stem cells and the inability of ovarian germline stem cells to undergo oogenesis. Although animals subjected to Smed-boule RNAi lose their gametes and become sterile, they continue …

Social Communication As An Early Indicator Of Autism In High-Risk Infant Populations, Alexis Marie Brewer

Senior Theses

This senior thesis analyzes the social communicative profiles of children at high-risk for autism compared to typically developing controls. The project focuses specifically on the differences in initiating joint attention gaze shifts and joint attention gestures at 12 months in two high-risk groups, children with fragile X syndrome and younger siblings of children already diagnosed with autism. Their frequencies of gaze shifts and gestures were also analyzed to determine whether the joint attention behaviors are indicative of later autism symptom severity at 24 months.

Standpoint: Black Queer Southern Revelations, Mitchell Joseph Sewell

Senior Theses

This senior thesis project is a collection of spoken word poetry organized around the theme of the experience of one black, southern, queer man.

Pyoderma Gangrenosum: An Over Treated And Underdiagnosed Mimicker Of Ulcers, A Case Presentation, Blake Shaffer Md, S Reynolds Ms3, Hina A. Sheikh Md, S Smith

Department of Medicine

No abstract provided.

Association Of Sleep Behavior To Physical Activity And Bmi In 9th And 10th Grade Students, Sonia Lina Davda

Senior Theses

Despite the topic’s popularity in research, the relationship between sleep duration and physical activity (PA) remains unclear. Measurement protocol differences, highly specific samples, and incomplete data contribute to varying results suggesting that additional research is needed. The purpose of the TRACK II study was to examine the relationship between PA, BMI, and self-reported sleep in adolescents. 369 9 th and 10 th grade students from 2 diverse school districts participated in the study. Participants completed a self-reported sleep questionnaire and had their height and weight measured. Demographic variables were also reported by participants. Actigraph accelerometers were used to objectively measure …

Effect Of Epha4 Signaling Mutations On Auditory Function, Michelle R. Gerringer

Dissertations, 2014-2019

Neural pathways underlie the ability of the auditory system to perceive sound. Organization of neural pathways into functional auditory circuitry is accomplished in part by Eph and ephrin signaling proteins. One of these signaling proteins, the EphA4 receptor tyrosine kinase protein, acts as an axon-guidance molecule to aid in target selection and to maintain tonotopicity in the auditory brainstem and midbrain. Genetic mutations of the EphA4 protein have been shown to affect structural auditory development, but there is limited research which shows the functional effects of these mutations. The goal of the present study was to determine the functional effects …

Inter-Professional Collaboration: The Impact Of Serial Versus Merged Treatment On The Behavior Of Children With Autism Spectrum Disorder, Robyn Starry

Masters Theses, 2010-2019

Interdisciplinary collaboration is an innovative, resourceful approach to healthcare intended to positively affect patient outcomes. The purpose of the present study was to determine the efficacy of the serial exposure to three treatments, Applied Behavior Analysis, Speech Language Pathology, and Occupational Therapy, in comparison with an exposure to a merge of these treatments on child outcomes. During the serial treatment phases of intervention, three licensed professionals implemented core techniques from their respective disciplines. During merged treatment phases, a graduate clinician combined and implemented techniques from all three fields: differential attention, request sequences, sensory exposure, verbal/tactile cueing for postural alignment/control and …

Are There Bad Wins And Good Losses? Outcome Effects In Sport, Richard Erik Inglis

Masters Theses, 2010-2019

Abstract

Outcomes have been shown to distort feeling states, performance evaluations, and subsequent performances. This retrospective distortion represents an outcome bias, a phenomenon that has been studied extensively in a wide array of disciplines and domains. However, despite their importance, the effects of outcomes have received little attention in the sport corpus. In an attempt to remedy this oversight, 60 participants with basketball experience were recruited to take part in a free throw shooting competition. Participants completed two rounds of 20 free throws. Following their first round, participants were randomly assigned to either a negative outcome (lose by one shot) …

A Mixed Methods Analysis Of The Relationship Between Attachment, Post-Traumatic Stress, And Post-Traumatic Growth Among United States Service Members, Chauncy T. Brinton

Dissertations, 2014-2019

The impact of secure military relationships on US service members’ response to trauma during military service was examined in this mixed methods study. Veterans with and without combat exposure evidence a high rate of post-traumatic stress disorder (PTSD) and the military has tried to institute resilience-based programs in anticipation of the psychological challenges experienced by soldiers. At the same time, research has shown that some service members report positive outcomes associated with military service including the phenomena of post-traumatic growth (PTG). The constructs from attachment theory (safe haven and exploration) have begun to be the focus of research with service …

Zn(Ii), Cu(Ii), Sn(Ii), And Ni(Ii) And Other Metal Cations Do Not Prevent The Aggregation Of Hiapp, Charles Hoying

Honors Thesis

The Zn(II) metal ion has been shown to interact with Islet Amyloid Polypeptide (IAPP), a protein implicated in the progression of Type II Diabetes Mellitus, in such a way as to prevent the protein from aggregating into toxic fibers. We set out to find whether other metal ions might similarly prevent IAPP aggregation. Using Thioflavin T (ThT) spectroscopic assays, which measure fluorescence of ThT upon binding to aggregated IAPP, we observed a decrease in aggregation when incubated with Zn(II), Cu(II), Ni(II), and Sn(II). Atomic Force Microscopy (AFM), which can visualize fibril formation, revealed that the metals were not inhibiting IAPP …

Potential Health Risks Associated With The Use Of Otc Ephedra-Free Weight Loss Products, Jennifer Good

Nursing Capstones

No abstract provided.

Management Of Hypertension In African Americans As Compared To Non-African Americas, Jamie C. Hanrahan

Nursing Capstones

No abstract provided.