Medicine and Health Sciences Commons^™

National Trends In Off-Label Use Of Atypical Antipsychotics In Children And Adolescents In The United States, Minji Sohn, Daniela C. Moga, Karen Blumenschein, Jeffery C. Talbert

Pharmacy Practice and Science Faculty Publications

The objectives of the study were as follows: to examine the national trend of pediatric atypical antipsychotic (AAP) use in the United States; to identify primary mental disorders associated with AAPs; to estimate the strength of independent associations between patient/provider characteristics and AAP use. Data are from the National Ambulatory Medical Care Survey and the National Hospital Ambulatory Medical Care Survey. First, average AAP prescription rates among 4 and 18-year-old patients between 1993 and 2010 were estimated. Second, data from 2007 to 2010 were combined and analyzed to identify primary mental disorders related to AAP prescription. Third, a multivariate logistic …

Postoperative Intussusception In 10-Year-Old Presenting As Decreased Intestinal Motility, Arielle Spellun, Loren Berman, Stephen Murphy

Department of Medicine Faculty Papers

No abstract provided.

Preferred Features Of E-Mental Health Programs For Prevention Of Major Depression In Male Workers: Results From A Canadian National Survey, Jianli Wang, Raymond W. Lam, Kendall Ho, Mark Attridge, Bonnie M. Lashewicz, Scott B. Patten, Alain Marchand, Alice Aiken, Norbert Schmitz, Zul Merali

Brain and Mind Institute

Background: Major depression is a prevalent mental disorder and imposes considerable burden on health and productivity. Men are not immune to major depression, yet they often delay seeking help because of perceived stigma and gender norms. E-mental health programs hold potential for early prevention of major depression. However, we have little knowledge about men's preferences for design features of e-mental health programs.

Objectives: The objective of this study was to (1) estimate and compare the proportions of Internet use for medical information, preferred design features, and likely use of e-mental health programs; (2) examine factors associated with the likely use …

Oncolog, Volume 61, Number 06, June 2016, Jill Delsigne, Joe Munch, Kathryn Hale, B Strubberg

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Proton Therapy Trials May Provide More Options for Patients with Non-Small Cell Lung Cancer: Proton therapy offers the potential to deliver a higher radiation dose to lung tumors and a lower dose to healthy tissues than does standard radiation therapy. However, the effectiveness of proton therapy has not yet been documented in clinical trials for patients with non-small cell lung cancer (NSCLC), the most common type of lung cancer. Two ongoing trials of proton therapy aim to demonstrate its effectiveness and may change the standard of care for NSCLC.
• Innovative "Basket" Trial Shows Promise of BRAF Inhibition in Various Cancers: …

The Relationship Between Lexical Performance And Regional Gray Matter Volumes: A Longitudinal Study Of Cognitively Healthy Elderly, Jungmoon Hyun

Dissertations, Theses, and Capstone Projects

This study investigated the longitudinal relationship among aging, performance on lexical tasks, and regional gray matter volumes over 2-7 years. A total of 137 older participants who remained cognitively normal were administered four lexical tasks at each time point: the Boston Naming Test (BNT), Vocabulary Test, Semantic- and Phonemic-Fluency task. In addition, they underwent repeated magnetic resonance imaging (MRI) scanning acquired within two months of the lexical tasks. The average interval between time points was 2.36 years (range 1.50-7.64) and the average number of time points was 2.65 times (range 2-5).

Results indicated that age differentially affects lexical task performance …

Heavy Expectations: Reading Pregnancy In The Victorian Novel, Livia Arndal Woods

Dissertations, Theses, and Capstone Projects

This dissertation articulates the tendency of Victorian novels to make legible only the pregnant bodies of immodest characters who transgress gendered ideologies while the pregnant bodies of modest characters tend to go undescribed. Tracing the medicalization of pregnancy and childbirth over the course of the long nineteenth century, my chapters demonstrate the function of moralizing narrative conventions in the representation of pregnancy in mid-Victorian novels, of a self-conscious use of free indirect diagnosis in high-Victorian fiction, and a shift at the fin-de-siècle from pregnancy as a signifier of morality to a symptom of unstable minds. The novels I read closely …

The Goat Semen Quality After Being Frozen Using Albumin And Cholesterol Substituted For Egg Yolk In Semen Extender, Terdchai Kaewkesa, Anucha Sathanawongs, Apichart Oranratnachai, Jureerat Sumretprasong

The Thai Journal of Veterinary Medicine

The objective of this study was to determine the effect of albumin and cholesterol substituted for egg yolk in goat semen extender after frozen-thawed on semen quality and pregnancy rate. The semen was collected from three bucks by using artificial vagina. The semen was divided into 5 groups; in group 1, seminal plasma was removed and 20% egg yolk extender was added (standard), in group 2, 2% egg yolk extender was added into whole semen (control), in group 3, 4 mg/mL albumin extender was added into whole semen, in group 4, 5 mg/mL cholesterol extender was added into whole semen, …

Genetic Parameters Of Semen Quality Traits And Production Traits Of Pure-Bred Boars In Thailand, Krittaphak Buranawit, Nalinee Imboonta

The Thai Journal of Veterinary Medicine

The objective of this study was to estimate genetic parameters for semen quality and production traits of pure-bred Finnish-Norwegian boars raised in Thailand. Data used in this study were 9,760 records of semen collection and 108 records of performance tests (from 25 Duroc, 59 Landrace, and 24 Yorkshire boars). Semen quality traits considered per collection were semen volume (SV), semen concentration (SC), total sperm (TS), and total abnormality (TA). Data were recorded from 2001 to 2009, except for TA, which was not recorded until 2003. Production measures from each boar were average daily gain (ADG) and backfat thickness (BF). Results …

Pulp-Dentin Complex Response To Ru-Hbm1, A Novel Resin Modified Glass Ionomer Cement Prototype, In Deep Cavity Preparation Of Porcine Teeth, Wijit Banlunara, Siriporn Songsiripadapboon, Sirithan Jiemsirilers, Onusa Saravari, Dujreutai Pongkao Kashima, Nonglax Thunyakitpisal, Pasakorn Brikshavana, Phanitnan Srisuwan, Thitima Rupunt, Pasutha Thunyakitpisal

The Thai Journal of Veterinary Medicine

The objective of this study was to evaluate the response of the pulp-dentin complex to Research Unit-Herbal Medicine, Biomaterial and Material 1 (RU-HBM1), a resin-modified glass ionomer (RMGI) cement prototype, in deep cavity of porcine teeth compared with commercial RMGIs. Six 14-week-old pigs were used in this study. Deep class V cavity was created on the buccal surface of canine, premolar, and molar teeth. The teeth were randomly lined with the design cement bases: RU-HBM1, Vitrebond (VB), or GC-Gold Label Light-Cured Universal Restorative (GC). After that, the cavity walls were treated with 30% phosphoric acid and washed. Then, a bonding …

Electrocardiographic Changes In Dogs With Degenerative Mitral Valve Disease Treated With Pimobendan: A Retrospective Study Of 29 Cases, Sirilak Disatian Surachetpong, Nisarat Boonlue, Pasorn Pupa, Waratsarin Boonsathitanan, Sumanee Rakthaidee, Tanawan Mangklabruks, Siriwan Sakarin

The Thai Journal of Veterinary Medicine

The aim of this retrospective study was to evaluate changes in electrocardiograms (ECG) and cardiac arrhythmias in 29 dogs with degenerative mitral valve disease (DMVD) treated with pimobendan chronically. All dogs had normal ECG before pimobendan administration. The dogs were classified according to ECG after pimobendan administration into 2 groups: normal ECG (n=19) and abnormal ECG (n=10). Age, sex, breed, serum alkaline phosphatase, concurrent digoxin administration, total daily dosage of pimobendan and digoxin, duration of pimobendan administration, and ECG parameters including heart rate, P wave, PR interval, QRS complex, and QT interval were analyzed. Cardiac arrhythmias were increasingly found in …

Comparative Proteomic Analysis Of Cow Placentas With Retained Foetal Membranes, Shixin Fu, Yao Liu, Tiantian Nie, Chengyuan Zheng, Xiao Zou, Chunhai Luo, Jianying Liu

The Thai Journal of Veterinary Medicine

Retained foetal membrane (RFM) is a common reproductive pathology that harms the health of dairy cows. The aim of this study was to clarify the pathogenesis of RFM and screen for an early clinical diagnostic marker of this disease by using comparative proteomics and bioinformatics. Three RFM placental tissues from three cows and an equal number of normal placental tissues were collected for this study. There were 240 spots showing significant differential expressions of known proteins between the two types of foetal placental tissue samples. Between the two maternal placental tissue samples, there were 214 spots with differentially expressed levels …

Identification Of Novel Snps And 10 Bp Deletion Of Ovine Dgat1 Gene And Their Association With Milk Production Traits, Ozge Ozmen, Selim Kul

The Thai Journal of Veterinary Medicine

Acyl coenzyme A: diacylglycerol acyltransferase 1 (dgat1) plays a key role in triacylglycerol synthesis by catalyzing the final committed step in the formation of triglycerides. Moreover, it could be used as a positional marker gene associated with milk production and composition traits. The purpose of the study was to identify genotype frequencies of single nucleotide polymorphisms (SNPs) in ovine dgat1 gene and its possible association with milk traits in dairy sheep breeds. The genetic structures of SNPs were examined by PCR-RFLP and DNA sequencing in three sheep populations. Significant association of dgat1 gene of the intron 16 g.8384T>C loci …

Allergen Sensitization Patterns Of Allergic Dogs: Ige-Microarray Analysis, Yun-Hsia Hsiao, Charles Chen, Ton Willemse

The Thai Journal of Veterinary Medicine

It was the aim of this study to determine sensitization rates to environmental allergens in 50 dogs with allergic dermatitis. Protein microarray of the dogs’ sera was used to identify allergen-specific IgE against 25 most common allergens. Increased IgE levels were most frequently observed for house dust mites (D. pteronyssinus 42.0%, D. farinae 38.0%) and storage mites (22-50%). In particular, the dogs with non-food-induced allergic dermatitis showed higher sensitization rates to mites compared to the dogs with food-induced allergic dermatitis, or a combination thereof. Reactions to insects were, with the exception of one dog sensitized to cockroach, entirely negative, and …

Protective Efficacy Of Live Lasota Strain Newcastle Disease Virus Vaccine In Layer-Type Chickens, Jiroj Sasipreeyajan, Phornphisut Areeraksakul, Somkid Khanda

The Thai Journal of Veterinary Medicine

The purpose of this study was to evaluate the protective efficacy of live LaSota strain Newcastle disease virus (NDV) vaccine administered with different routes against a NDV challenge in layer-type chickens. Fifty male layer-type chickens were divided into 3 groups. There were 20 chickens/group for the vaccinated groups (Groups 1 and 2) and 10 chickens for the non-vaccinated control group (Group 3). Chickens in Groups 1 and 2 received the vaccine individually at 4 weeks old by eye drop and oral drop, respectively. All chickens received NDV challenge individually by oral drop at 7 weeks old or 3 weeks post-vaccination …

Diversity Of Non-Flavobacterium Columnare Bacteria Associated With Columnaris-Like Diseased Fish, Ha Thanh Dong, Vuong Viet Nguyen, Wanniwat Mata, Pattanapon Kayansamruaj, Saengchan Senapin, Dachrit Nilubol, Channarong Rodkhum

The Thai Journal of Veterinary Medicine

Numerous yellow and pink pigmented bacterial isolates had been recovered from diseased fish exhibiting columnaris-like disease in tilapia (Oreochromis spp.) farms in Thailand. The predominant species had been identified as Flavobacterium columnare while taxonomic classification of the remaining isolates and their pathogenic potential remain undetermined. An additional yellow bacterial strain had also been obtained from a koi carp sample showing columnaris-like symptoms. To continue our previous work, this study described the identification of ten representatives of unknown culturable non-Flavobacterium columnare bacteria based on a combination of phenotypic characteristics and nucleotides homology of 16S rRNA gene and subsequently investigated their pathogenicity …

Bactericidal Effects Of Povidone-Iodine And Chlorhexidine Gluconate On Coagulase-Positive Staphylococci, Punpichaya Fungwithaya, Nuvee Prapasarakul

The Thai Journal of Veterinary Medicine

We aimed to evaluate the in vitro bactericidal efficacy of two routine antiseptics used in veterinary hospital, povidone-iodine and chlorhexidine gluconate in isopropanol (CGI),against canine coagulase-positive staphylococci (CoPS). Twenty CoPS were divided into 5 methicillin-resistant Staphylococcus pseudintermedius (MRSP) and 5 isolates each of S. pseudintermedius, S. aureus and S. schleiferi subsp. coagulans defined as methicillin-susceptible CoPS (MSCoPS). The bactericidal efficacy was determined by broth microdilution according to European Standard EN 1656:2000 at concentrations of 0.1, 1 and 10% PI and 0.5, 1 and 2% CGI for 15s, 30s, 45s, 1 min, 3 min and 5 min, respectively. There was no …

Identification Of Competitive Exclusion And Its Ability To Protect Against Campylobacter Jejuni In Broilers, Thotsapol Thomrongsuwannakij, Rungtip Chuanchuen, Niwat Chansiripornchai

The Thai Journal of Veterinary Medicine

This study aimed to identify competitive exclusion (CE) isolated from native chickens and organic layers raised under non-antimicrobial usage farms. The protection of CE was tested against Campylobacter jejuni challenges in broilers. Lactobacillus spp., Bacillus spp. and Enterococcus faecium were identified from 50 adult chicken feces of those farms. According to antimicrobial-resistance concerns of European Food Safety Authority (EFSA), the use of CE that is susceptible to antimicrobials is preferred. The numbers of Lactobacillus spp., Bacillus spp. and Enterococcus faecium equal to 195, 93 and 58 strains, respectively, were tested for their minimum inhibitory concentrations (MICs) of 10 antimicrobials. As …

Ophthalmology Snapshot, Nalinee Tuntivanich

The Thai Journal of Veterinary Medicine

No abstract provided.

Selection Of Reference Genes For Real-Time Polymerase Chain Reaction In Canine Oral Tumor And Cancer, Sirinun Pisamai, Anudep Rungsipipat, Chanin Kalpravidh, Gunnaporn Suriyaphol

The Thai Journal of Veterinary Medicine

Tumors in oral cavity either benign or malignant are often found in dogs. Despite the increasing number of studies of gene expression associated with canine oral cavity diseases, reference gene selection for normalizing target genes has not been performed. The objective of the present study was to identify potential reference genes in canine oral tumors, including epulis, ameloblastoma, oral melanoma, oral squamous cell carcinoma, etc. Suitability of 6 candidate reference genes, beta-actin (ACTB), beta-2-microglobulin (B2M), glyceraldehydes-3-phosphate dehydrogenase (GAPDH), ribosomal subunit L13a (RPL13a), ribosomal protein S5 (RPS5) and ribosomal protein S19 (RPS19), was evaluated with 5 algorithms, geNorm, Normfinder, BestKeeper, the …

What Is Your Diagnosis?, Nan Choisunirachon

The Thai Journal of Veterinary Medicine

No abstract provided.

Urethral Rupture And Leakage Following Prolonged Surgical Removal Of Urethral And Bladder Stones By Episiotomy And Urethrotomy In Female Asian Elephant (Elephas Maximus) : A Case Report, Nikorn Thongtip, Benchapol Lorsunyaluck, Manakorn Sukmak, Sirinart Chaichanathong, Pornchai Sunyathitiseree

The Thai Journal of Veterinary Medicine

A 46-year-old female Asian elephant (Elephas maximus) with an abnormal ballottement mass in the perineal area was presented. The elephant was unable to urinate via the normal tract. Previously, this elephant was treated for urethral and bladder obstruction caused by stones by episiotomy and urethrotomy. Eight months later, post-operative care was completed. At this point, the incision wound completely closed and the elephant could urinate through the normal tract. However, the elephant was then mated with an adult male elephant. Three weeks later, the female showed signs of the perineal ballottement mass and was unable to urinate. Episiotomy and urethrotomy …

Diagnosis Of Pharyngeal Sialocele In A Dog By Ct Scan : A Case Report, Sekkarin Ploypetch, Nan Choisunirachon, Chanin Kalpravidh

The Thai Journal of Veterinary Medicine

A 7-year-old, 10 kg male poodle dog was presented at the Small Animal Teaching Hospital, with the clinical signs of chronic coughing, bad deglutition and severe respiratory distress. On oral examination, a large mass arisen from the throat was found. Because the skull-cervical radiographs revealed only a large soft tissue pharyngeal mass which were difficult to indicate the mass types and the tissue invasiveness, the computed tomography (CT) was subsequently applied. The CT result showed that the mass was an encapsulated hypoattenuation mass (2.5 x 4.3 x 2.4 cm) at the right pharyngeal area without any adjacent soft tissue invasions. …

Ultrasound Diagnosis, Phiwipha Kamonrat

The Thai Journal of Veterinary Medicine

No abstract provided.

Ameliorative Effects Of Omega-3 Concentrate In Managing Coxofemoral Osteoarthritic Pain In Dogs, Amornrate Sastravaha, Nirut Suwanna, Chayakrit Sinthusingha, Jatuporn Noosud, Atthaporn Roongsitthichai

The Thai Journal of Veterinary Medicine

The aim of the present study was to investigate the effect of omega-3 concentrate on pain management in dogs with osteoarthritis (OA) at the coxofemoral joint. Totally, 31 dogs with confirmed coxofemoral OA were orthopedically evaluated for pain scores at walk and trot (1-6), joint manipulation (1-3), and examining range of motion (1-4). Besides, blood collection was performed on the first and the last visits. Omega-3 concentrate was orally given to all dogs at one capsule per 10 kgBW since the first visit on a daily basis for four consecutive weeks. On a weekly basis, pain scores were assessed for …

Ecg Quiz, Chollada Buranakarl, Anusak Kijtawornrat, Saikaew Sutayatram

The Thai Journal of Veterinary Medicine

No abstract provided.

Mentors And Role Models: Two Approaches For Inspiration, Gary L. Stafford

School of Dentistry Faculty Research and Publications

No abstract provided.

Intersubunit Interactions At Putative Sites Of Ethanol Action In The M3 And M4 Domains Of The Nmda Receptor Glun1 And Glun2b Subunits, Robert W. Peoples, Hong Ren, Yulin Zhao

Biomedical Sciences Faculty Research and Publications

Background and Purpose: The N-methyl-D-aspartate (NMDA) receptor is an important target of alcohol action in the brain. Recent studies in this laboratory have demonstrated that alcohol-sensitive positions in the intersubunit interfaces of the M3 and M4 domains of GluN1 and GluN2A subunits interact with respect to ethanol sensitivity and receptor kinetics, and that alcohol-sensitive positions in the M domains of GluN2A and GluN2B subunits differ. In this study we tested for interactions among alcohol-sensitive positions at the M domain intersubunit interfaces in GluN1/GluN2B NMDA receptors.

Experimental Approach: We used whole-cell patch-clamp recording in tsA201 cells expressing tryptophan substitution mutants at …

Cost Of Management Of Severe Pneumonia In Young Children: Systematic Analysis, Shanshan Zhang, Peter M. Sammon, Isobel King, Ana Lucia Andrade, Cristiana M. Toscano, Sheila N. Araujo, Anushua Sinha, Shabir A. Madh, Gulam Khandaker, Jiehui Kevin Yin, Robert Booy, Tanvir M. Huda, Qazi S. Rahman, Shams El Arifeen, Angela Gentile, Norberto Giglio, Mejbah U. Bhuiyan, Katharine Sturm Ramirez, Bradford D. Gessner, Mardiati Nadjib, Phyllis J. Carosone– Link, Eric Af Simões, Jason A. Child, Imran Ahmed, Zulfiqar Ahmed Bhutta, Sajid Bashir Soofi

Department of Paediatrics and Child Health

Background: Childhood pneumonia is a major cause of childhood illness and the second leading cause of child death globally. Understanding the costs associated with the management of childhood pneumonia is essential for resource allocation and priority setting for child health.
Methods: We conducted a systematic review to identify studies reporting data on the cost of management of pneumonia in children younger than 5 years old. We collected unpublished cost data on non–severe, severe and very severe pneumonia through collaboration with an international working group. We extracted data on cost per episode, duration of hospital stay and unit cost of interventions …

Icd-10 Implementation: What Impact Did It Have On Medical Facilities Across The Country?, Tammy Collins

Applied Research Projects

The Department of Health and Human Services mandated that all Health InsurancePortability and Accountability Act (HIPAA) covered entities implement The International Classification of Diseases tenth edition (ICD-10) on October 1, 2015. The United States was the last industrialized country to move to the new coding system. A survey of HIM professionals was conducted across the United States to determine what efforts they experienced during the implementation of ICD-10; outline a timeline of implementation efforts for the transition of ICD-9 to ICD-10; uncover the major expenses organizations incurred through the implantation process; define training initiatives; and disclose the financial impact the …

Internet And Social Media: Influence On The Parent’S Vaccination Decision, Laura Piscaglia

Applied Research Projects

Information is now abundantly available with a click of a button. Access to more information imaginable can be obtained instantly. Unfortunately, not all of this information is backed by scientifically researched facts. This is causing problems for the healthcare industry, especially in the area of vaccinations. Scientifically sound information provided by the healthcare providers is being challenged by information parents are finding that is provided by the anti-vaccination movement. This information is found on websites, shared on social media, and is spreading rapidly. This research investigates this conflicting information between healthcare providers and the anti-vaccination movement. It is designed to …