Medicine and Health Sciences Commons^™

25(Oh)D Status Of Elite Athletes With Spinal Cord Injury Relative To Lifestyle Factors, Kelly Pritchett, Robert Pritchett, Dana Ogan, Phil Bishop, Elizabeth Broad, Melissa Lacroix

All Faculty Scholarship for the College of the Sciences

Background: Due to the potential negative impact of low Vitamin D status on performance-related factors and the higher risk of low Vitamin D status in Spinal Cord Injury (SCI) population, research is warranted to determine whether elite athletes with SCI have sufficient 25(OH)D levels. The purposes of this study were to examine: (1) the seasonal proportion of vitamin D insufficiency among elite athletes with SCI; and (2) to determine whether lifestyle factors, SCI lesion level, and muscle performance/function are related to vitamin D status in athletes with SCI. Methods: Thirty-nine members of the Canadian Wheelchair Sports Association, and the US …

College Of Public Health News, Georgia Southern University

College of Public Health: News & Publications

• Georgia Southern Examines a More Efficient Logistic Analysis
• Georgia Southern Alum Selected as commencement speaker

Nurses' Involvement In Hiv Policy Formulation In Nigerian Health Care System, Ekaete Asuquo, Josephine Bassey Etowa, Wendy A. Gifford, Dave Holmes

School of Nursing & Midwifery, East Africa

Background of study: Nigerian national policy on HIV stresses the need for the adoption of multi-sectoral and multi-disciplinary approach in policy formulation, with the health sector taking the lead. This calls for collaboration among the various stakeholders including nurses in policy development initiatives to ensure that diverse health care needs and disciplinary perspectives are captured in HIV health policies.

Purpose: This paper will present the findings of a recent study which examined nurse’s involvement in policy development in the context of mother-to-child transmission (MTCT) of HIV in Nigeria.

Methodology: A qualitative case study design under the guiding tenets of critical …

Community Health News, Georgia Southern University

Health Policy & Community Health: News & Publications (2011-2018)

• Georgia Southern Alum Selected as Commencement Speaker

Barriers And Facilitators To Cervical Cancer Screening Among Iraqi Refugees Resettled In Philadelphia: A Qualitative Analysis Of Patient And Provider Perceptions, Colleen Payton, Mph, Ches, Laura Parente, Md, Dalea Al-Hawarri, Md, Philip Manasseh, Mph, Kevin Scott, Md, Marc Altshuler, Md

Department of Family & Community Medicine Presentations and Grand Rounds

Oral presentation at the 6^th Annual North American Refugee Health Conference, Niagara Falls, New York.

Research Questions:

1. What is the prevalence of cervical cancer and cervical cancer screening among recently resettled refugees seen at Jefferson's Center for Refugee Health?

2. Are patient-and provider-identified barriers to cervical cancer screening at CRH consistent with those identified in previous research efforts?

3. What are patient-and provider identified facilitators to cervical cancer screening for Iraqi refugee women?

Comprehensive Refugee Health Surveillance In Philadelphia: A Combined Resettlement And Clinical Patient Registry, Colleen Payton, Mph, Ches, Brittany Divito, Mph, Bsn, Rn, Gretchen Shanfeld, Mph, Zoe Agoos, Md, Kevin Scott, Md, Marc Altshuler, Md

Department of Family & Community Medicine Presentations and Grand Rounds

Oral presentation at the 6^th Annual North American Refugee Health Conference, Niagara Falls, New York.

Goal:

To improve the success of refugee resettlement and health outcomes in Philadelphia by establishing a multi-agency registry with social services and clinical measures.

N-Acetyl Cysteine May Support Dopamine Neurons In Parkinson's Disease: Preliminary Clinical And Cell Line Data., Daniel A. Monti, George Zabrecky, Daniel Kremens, Tsao-Wei Liang, Nancy A. Wintering, Jingli Cai, Xiatao Wei, Anthony J. Bazzan, Li Zhong, Brendan Bowen, Charles Intenzo, Lorraine Iacovitti, Andrew B. Newberg

Marcus Institute of Integrative Health Faculty Papers

BACKGOUND: The purpose of this study was to assess the biological and clinical effects of n-acetyl-cysteine (NAC) in Parkinson's disease (PD).

METHODS: The overarching goal of this pilot study was to generate additional data about potentially protective properties of NAC in PD, using an in vitro and in vivo approach. In preparation for the clinical study we performed a cell tissue culture study with human embryonic stem cell (hESC)-derived midbrain dopamine (mDA) neurons that were treated with rotenone as a model for PD. The primary outcome in the cell tissue cultures was the number of cells that survived the insult …

Expression Of Μ-Protocadherin Is Negatively Regulated By The Activation Of The Β-Catenin Signaling Pathway In Normal And Cancer Colorectal Enterocytes., Lucia Montorsi, Sandra Parenti, Lorena Losi, Fabrizio Ferrarini, Claudia Gemelli, A Rossi, Gianrocco Manco, Stefano Ferrari, Bruno Calabretta, Enrico Tagliafico, Tommaso Zanocco-Marani, Alexis Grande

Department of Cancer Biology Faculty Papers

Mu-protocadherin (MUCDHL) is an adhesion molecule predominantly expressed by colorectal epithelial cells which is markedly downregulated upon malignant transformation. Notably, treatment of colorectal cancer (CRC) cells with mesalazine lead to increased expression of MUCDHL, and is associated with sequestration of β-catenin on the plasma membrane and inhibition of its transcriptional activity. To better characterize the causal relationship between β-catenin and MUCDHL expression, we performed various experiments in which CRC cell lines and normal colonic organoids were subjected to culture conditions inhibiting (FH535 treatment, transcription factor 7-like 2 siRNA inactivation, Wnt withdrawal) or stimulating (LiCl treatment) β-catenin activity. We show here …

Hydrothermally Processed 1d Hydroxyapatite: Mechanism Of Formation And Biocompatibility Studies, Zoran Stojanović, Nenad Ignjatović, Victoria M. Wu, Vojca Žunič, Ljiljana Veselinović, Srečo D. Škapin, Miroslav Miljković, Vuk Uskoković, Dragab Uskoković

Pharmacy Faculty Articles and Research

Recent developments in bone tissue engineering have led to an increased interest in one-dimensional (1D) hydroxyapatite (HA) nano- and micro-structures such as wires, ribbons and tubes. They have been proposed for use as cell substrates, reinforcing phases in composites and carriers for biologically active substances. Here we demonstrate the synthesis of 1D HA structures using an optimized, urea-assisted, high-yield hydrothermal batch process. The one-pot process, yielding HA structures composed of bundles of ribbons and wires, was typified by the simultaneous occurrence of a multitude of intermediate reactions, failing to meet the uniformity criteria over particle morphology and size. To overcome …

Pik3ca-Associated Developmental Disorders Exhibit Distinct Classes Of Mutations With Variable Expression And Tissue Distribution, Ghayda Mirzaa, Andrew E Timms, Valerio Conti, Evan August Boyle, Katta M Girisha, Beth Martin, Martin Kircher, Carissa Olds, Jane Juusola, Sarah Collins, Kaylee Park, Melissa Carter, Ian Glass, Inge Krägeloh-Mann, David Chitayat, Aditi Shah Parikh, Rachael Bradshaw, Erin Torti, Stephen Braddock, Leah Burke, Sondhya Ghedia, Mark Stephan, Fiona Stewart, Chitra Prasad, Melanie Napier, Sulagna Saitta, Rachel Straussberg, Michael Gabbett, Bridget C O'Connor, Catherine E Keegan, Lim Jiin Yin, Angeline Hwei Meeng Lai, Nicole Martin, Margaret Mckinnon, Marie-Claude Addor, Luigi Boccuto, Charles E Schwartz, Agustina Lanoel, Robert L Conway, Koenraad Devriendt, Katrina Tatton-Brown, Mary Ella Pierpont, Michael Painter, Lisa Worgan, James Reggin, Raoul Hennekam, Karen Tsuchiya, Colin C Pritchard, Mariana Aracena, Karen W Gripp, Maria Cordisco, Hilde Van Esch, Livia Garavelli, Cynthia Curry, Anne Goriely, Hulya Kayserilli, Jay Shendure, John Graham, Renzo Guerrini, William B Dobyns

Articles, Abstracts, and Reports

Mosaicism is increasingly recognized as a cause of developmental disorders with the advent of next-generation sequencing (NGS). Mosaic mutations of PIK3CA have been associated with the widest spectrum of phenotypes associated with overgrowth and vascular malformations. We performed targeted NGS using 2 independent deep-coverage methods that utilize molecular inversion probes and amplicon sequencing in a cohort of 241 samples from 181 individuals with brain and/or body overgrowth. We identified PIK3CA mutations in 60 individuals. Several other individuals (n = 12) were identified separately to have mutations in PIK3CA by clinical targeted-panel testing (n = 6), whole-exome sequencing ( …

Development And Implementation Of Intensive Behavioral Therapy For Obesity In The Primary Care Setting, Kathleen Mcfadden, Meera Ramsooksingh, Steven Baltic, Vartika Bhardwaj, Glenn Deangelis, Thomas Kwarcinski Ms, Victoria Psomiadis, Adison Weseloh, Robin S. Schroeder Md

Department of Family Medicine

No abstract provided.

Developing A Video-Based Ehealth Intervention For Hiv-Positive Gay, Bisexual, And Other Men Who Have Sex With Men: Study Protocol For A Randomized Controlled Trial, Sabina Hirshfield, Martin J. Downing Jr., Jeffrey T. Parsons, Christina Grov, Rachel J. Gordon, Steven T. Houang, Roberta Scheinmann, Patrick S. Sullivan, Irene S. Yoon, Ian Anderson, Mary Ann Chiasson

Publications and Research

Background: Gay, bisexual, and other men who have sex with men (GBMSM) accounted for 67% of new US human immunodeficiency virus (HIV) infections in 2012; however, less than 40% of HIV-positive GBMSM are virally suppressed. Preventing transmission from virally unsuppressed men who have condomless anal sex (CAS) with serodiscordant partners is a public health imperative. New HIV infections in GBMSM are attributed in part to online access to sex partners; therefore, low-cost eHealth interventions are a unique opportunity to reach men where they meet partners.

Objective: To describe the protocol of a randomized controlled trial evaluating whether video-based messaging delivered …

Feasibility Of Conducting A Web-Based Survey Of Patient-Reported Outcomes And Rehabilitation Progress, Jennifer S. Howard, Jenny L. Toonstra, Amanda R. Meade, Caitlin E. Whale Conley, Carl G. Mattacola

Physical Therapy Faculty Publications

Background: Web-based surveys provide an efficient means to track clinical outcomes over time without the use of clinician time for additional paperwork. Our purpose was to determine the feasibility of utilizing web-based surveys to capture rehabilitation compliance and clinical outcomes among postoperative orthopedic patients. The study hypotheses were that (a) recruitment rate would be high (> 90%), (b) patients receiving surveys every two weeks would demonstrate higher response rates than patients that receive surveys every four weeks, and (c) response rates would decrease over time.

Methods: The study design involved a longitudinal cohort. Surgical knee patients were recruited for study …

Conceptual Model Of Weight Management In Overweight And Obese African-American Females, Suzanne M. Sutton, Gayenell S. Magwood Phd, Rn, Faha, Faan, Lynne S. Nemeth, Carolyn M. Jenkins

Publications

PROBLEM: Weight management of overweight and obese (OWO) African-American females (AAFs) is a poorly defined concept, leading to ineffective treatment of overweight and obesity, prevention of health sequelae, and risk reduction. METHODS: A conceptual model of the phenomenon of weight management in OWO AAFs was developed through dimensional analysis of the literature. Constructs were identified and sorted into the dimensions of perspective, context, conditions, process, and consequences and integrated into an explanatory matrix. FINDINGS: Through dimensional analysis, weight management in OWO AAFs was characterized as a multidimensional concept, defined from the perspective of weight loss in community-dwelling AAFs. Behaviors associated …

Elimination Of Taenia Solium Transmission In Northern Peru, Hector H. Garcia, Armando E. Gonzalez, Victor C.W. Tsang, Seth E. O'Neal, Fernando Llanos‑Zavalaga, Guillermo Gonzalvez, Jaime Romero, Silvia Rodriguez, Luz M. Moyano, Viterbo Ayvar, Andre Diaz, Allen Hightower, Philip S. Craig, Marshall W. Lightowlers, Charles G. Gauci, Elli Leontsini, Robert H. Gilman

OHSU-PSU School of Public Health Faculty Publications and Presentations

Background: Taeniasis and cysticercosis are major causes of seizures and epilepsy. Infection by the causative parasite Taenia solium requires transmission between humans and pigs. The disease is considered to be eradicable, but data on attempts at regional elimination are lacking. We conducted a three-phase control program in Tumbes, Peru, to determine whether regional elimination would be feasible.

Methods: We systematically tested and compared elimination strategies to show the feasibility of interrupting the transmission of T. solium infection in a region of highly endemic disease in Peru. In phase 1, we assessed the effectiveness and feasibility of six intervention …

Dating As An Occupation: Swipe Right For Ot, Karen Mccarthy

Collected Faculty Scholarship

Background As occupational therapists (OTs) we claim to treat our clients holistically, yet despite research indicating the importance of sexuality in practice (White et al 1992, Northcott and Chard 2000) sexuality and the occupations surrounding it, such as dating, can often be ignored in practice. Sexuality is expressed through many forms including sexual activity, self care and dating. As OTs, how often do we acknowledge or actively address a client’s desire to find a partner and the occupations that surround such a goal? Krishnagiri discusses “mate selection” as an important occupation with rich cultural and personal significance to the person …

Duplication And Remolding Of Trna Genes In The Mitochondrial Genome Of Reduvius Tenebrosus (Hemiptera: Reduviidae), Pei Jiang, Hu Li, Fan Song, Yao Cai, Jianyun Wang, Jinpeng Liu, Wanzhi Cai

Markey Cancer Center Faculty Publications

Most assassin bugs are predators that act as important natural enemies of insect pests. Mitochondrial (mt) genomes of these insects are double-strand circular DNAs that encode 37 genes. In the present study, we explore the duplication and rearrangement of tRNA genes in the mt genome of Reduvius tenebrosus, the first mt genome from the subfamily Reduviinae. The gene order rearranges from CR (control region)-trnI-trnQ-trnM-ND2 to CR-trnQ-trnI2-trnI1-trnM-ND2. We identified 23 tRNA genes, including 22 tRNAs commonly found in insects and an additional trnI (trnI2), which has high sequence similarity to trnM. We found several …

Psychological Inflexibility Predicts Attitudes Toward Syrian Refugees And National Security Policies, Arthur T. Hatton Sr., Michael Nielsen

Psychology: Faculty Presentations (2009-2022)

Our research examines whether psychological inflexibility predicts support for national security policies that limit civil liberties, unfairly target Muslims, and exclude Syrian refugees from entering the country. New research has suggested that high psychological inflexibility may be implicated in prejudice (Vilardaga, Estevez, Levin, & Hayes, 2012). According to that theory, inflexibility may contribute to discriminatory behaviors because it describes a person's tendency to engage in behaviors aimed at down-regulating internal distress. Recently, an enormous number of refugees from Syria have relocated from Syria into the EU, other Middle Eastern Countries, and in the United States. A political backlash to both …

Sleep Duration Patterns From Adolescence To Young Adulthood And Their Impact On Asthma And Inflammation, Chighaf Bakour

USF Tampa Graduate Theses and Dissertations

This dissertation includes three studies that examined the impact of inadequate sleep duration in adolescents and young adults on asthma and systemic inflammation. We used data from the Florida Youth Risk Behavior Survey (YRBS), years 2009-2013, and from the National Longitudinal Study of Adolescent to Adult Health (Add health), which was conducted between 1994 and 2008.

The first study used data from 16,738 high school students participating in the Florida YRBS. We examined the cross-sectional association between sleep duration and asthma, and the interactive effects of sleep duration and BMI. We found that short and long sleep durations were associated …

Development And Validation Of A Remote Sensing Model To Identify Anthropogenic Boreholes That Provide Dry Season, Refuge Habitat For Anopheles Vector Mosquitoes In Sub-Saharan Africa, James Pkemoi Kukat

USF Tampa Graduate Theses and Dissertations

A lack of surveillance systems is an impediment to public health intervention for perennial vector-borne disease transmission in northern tropical savanna region of Kenya. The population in this area are mostly poor nomadic pastoralists with little acquired functional immunity to Plasmodium falciparum, due to infrequent challenges with the parasite. A common characteristic in tropical savanna climatic zone is the availability of riverbeds that have anthropogenic boreholes that provide malaria vector mosquitoes, such as Anopheles gambiae s.l and Anopheles funestus, with aquatic refuge habitats for proliferation and endemic transmission to proximity human households during the dry-season. Unfortunately, currently there …

Lifting Others, Kevin G. Budziszewski

Akesis

Medicine is full of paradoxes. As a species, we often need to take care of ourselves before we can take care of others. As humans, we become more energetic by the energy-intensive process of exercise. As physicians, we elevate ourselves by lifting others. Through all of the unexpected worries and complications that crop up in life – finances, illness, and indeed an understanding of our own mortality – it is through these three paradoxes of self-care that we survive the complications that life throws at us.

During my first year of medical school, I have grown to understand how important …

Making A Mountain Of A Mole Hill, Nihit N. Mehta

Akesis

There are times when students develop a certain amount of tunnel vision, which focuses their vision at the problem in front, making the proverbial "mountain out of a molehill.”

(Least) Complicated, Masina G. Wright

Akesis

The personal has always been a microcosm of the political.

Dear Mabel (Please Allow Me To Inhabit Your Pain Awhile), Jack C. Lewis

Akesis

This started as a note that I would have sent a patient I treated while working as a paramedic in Central Maine. Despite best intentions in caring for patients, we don't always walk away having "won." The practice of medicine is difficult for everyone, but it is necessarily a process and life-long endeavor.

Outcomes Of Unilateral And Bilateral Total Knee Arthroplasty In 238,373 Patients, Eric R. Bohm, Katy Molodianovitsh, Alina Dragan, Naisu Zhu, Greg Webster, Bas Masri, Emil Schemitsch, Michael Dunbar

Bone and Joint Institute

© 2016 The Author(s). Published by Taylor & Francis on behalf of the Nordic Orthopedic Federation. Background and purpose — There is no consensus about the outcome of simultaneous vs. staged bilateral total knee arthroplasty (TKA). We examined this issue by analyzing 238,373 patients. Patients and methods — Demographic, clinical, and outcome data were evaluated for TKA patients (unilateral: 206,771; simultaneous bilateral: 6,349; staged bilateral: 25,253) from the Canadian Hospital Morbidity Database for fiscal years 2006–2007 to 2012–2013. Outcomes were adjusted for age, sex, comorbidities, and hospital TKA volume. Results — Simultaneous bilateral TKA patients were younger than staged bilateral …

New Directions In Public Health Systems Research: The U.S. Context, Glen P. Mays

Health Management and Policy Presentations

Public health services and delivery systems have the potential to improve population health and reduce health inequities by intervening on pathways that connect social and economic determinants to health outcomes. This session profiles the developing field of public health services and systems research (PHSSR) in the United States and new research directions to better understand the current and potential impact of public health delivery systems on social and economic drivers of health. We discuss emerging opportunities for cross-national comparative research on public health delivery systems in the U.S. and Canada.

Data Correlations Between Gender, Cytomegalovirus Infection And T Cells, Nk Cells, And Soluble Immune Mediators In Elderly Humans, Ahmad Al-Attar, Steven R. Presnell, Charlotte A. Peterson, D. Travis Thomas, Charles T. Lutz

Pathology and Laboratory Medicine Faculty Publications

We describe a cohort of 50 elderly subjects, age at least 70 years. We present gender-specific findings in T lymphocyte markers and soluble immune mediators. We show the correlation between cytomegalovirus infection status with CD56^dim NK cell responses to a variety of stimuli and with CD56^bright/CD56^dim NK cell ratio. We also present the correlation of retinol binding protein (RBP)−4 plasma levels with NK cell responses and we explore the relationship between gender and adiponectin, 25(OH)D (vitamin D), and RBP4 in affecting CD56^dim NK cell responses. These data are discussed in Al-Attar et al. (2016)

Georgia’S Rural Hospital Closures: The Common-Good Approach To Ethical Decision-Making, Randi G. Bastain, Marcus Garner, John S. Barron, Emmanuel A. Akowuah, William A. Mase

Health Policy & Management: Faculty Publications (2006-2018)

Background: Critical access hospitals provide several essential services to local communities. Along with the functions associated with providing necessary medical care, they also offer employment opportunities and other economic benefits to the communities they serve. Since 2010, the number of rural hospitals closures has steadily increased. The common-good approach to ethical decision-making provides a framework that aids in evaluation of the effects that hospital closures have on rural residents and communities.

Methods: This analysis includes results of a systematic overview of peer-reviewed literature to address the following research questions: 1) How have state policies and the adoption of Medicaid expansion …

Nutritional Knowledge And Dietary Practices Among Division I Athletes: Do College Athletes Understand And Fulfill Sex Specific Nutritional And Metabolic Requirements?, Martina Loncarica Loncarica

Theses - ALL

ABSTRACT

Objective: This study evaluated and compared male and female college athletes’ dietary habits, their general nutrition knowledge, and understanding of their daily metabolic requirements during training and non-training days. The goal was to 1) determine whether a nutritional gender gap existed between male and female college athletes and 2) assess whether the level of nutritional knowledge of student athletes was generally sufficient to meet their sex- specific dietary needs.

Methods: A cross-sectional study design was used to gather dietary data from Syracuse University student athletes. Participants were asked to complete an online survey (Qualtrics Software, Qualtrics.com) approved by the …

Assessing The Health Impact Of Transnational Corporations: Its Importance And A Framework, Frances E. Baum, David M. Sanders, Matt Fisher, Julia Anaf, Nicholas Freudenberg, Sharon Friel, Ronald Labontée, Leslie London, Carlos Monteiro, Alex Scott-Samuel, Amit Sen

Publications and Research

Background: The adverse health and equity impacts of transnational corporations’ (TNCs) practices have become central public health concerns as TNCs increasingly dominate global trade and investment and shape national economies. Despite this, methodologies have been lacking with which to study the health equity impacts of individual corporations and thus to inform actions to mitigate or reverse negative and increase positive impacts.

Methods: This paper reports on a framework designed to conduct corporate health impact assessment (CHIA), developed at a meeting held at the Rockefeller Foundation Bellagio Center in May 2015.

Results: On the basis of the deliberations …