Medicine and Health Sciences Commons^™

The Effect Of Maternal Employment On Child Obesity, Bezawit T. Agiro

International Journal of African Development

Abstract

Obesity has been a major concern for the United States and most other industrialized countries over the past few decades. More than one third of children and adolescents in the United States are obese or overweight. Child obesity is of particular interest because overweight children are more likely to be overweight as adults, and such adults are exposed to various diseases. During the same period that witnessed an increase in child obesity, an important change that occurred was the increase in maternal employment. This study is an attempt to analyze the relationship between maternal employment and child obesity. This …

International Trade Effects Of Regional Economic Integration In Africa: The Case Of The Southern African Development Community (Sadc), Mengesha Yayo, Sisay Asefa

International Journal of African Development

Empirical studies on regional economic integration process in Africa exhibit sluggish progress, and there by limited level of intra-trade. The existing literature in Africa, particularly in the Southern African regional integration bloc, has neglected the effects of regional economic integration dealing with disaggregated data. This study analyzes trade creation and diversion effects of the Southern African Development Community (SADC) using disaggregated data. The investigation estimates an augmented gravity model using panel data and random effect estimator methods applying instrumental variables where needed.

The results show that intra-SADC trade is growing in the fuel and minerals and the heavy manufacturing sectors …

Hdac6 Inhibition Prevents Tnf-Α-Induced Caspase 3 Activation In Lung Endothelial Cell And Maintains Cell-Cell Junctions, Jinyan Yu, Mengshi Ma, Zhongsen Ma, Jian Fu

Center for Research on Environmental Disease Faculty Publications

Pro-inflammatory mediators such as TNF-α induce caspase activation in endothelial cells, which leads to degradation of cellular proteins, induction of apoptotic signaling, and endothelial cell dysfunction. New therapeutic agents that can inhibit caspase activation may provide protection against inflammatory injury to endothelial cells. In the present study, we examined the effects of selective histone deacetylase 6 (HDAC6) inhibition on TNF-α induced caspase 3 activation and cell-cell junction dysfunction in lung endothelial cells. We also assessed the protective effects of HDAC6 inhibition against lung inflammatory injury in a mouse model of endotoxemia. We demonstrated that selective HDAC6 inhibition or knockdown of …

The Clinical, Biochemical And Genetic Features Associated With Rmnd1-Related Mitochondrial Disease., Yi Shiau Ng, Charlotte L Alston, Daria Diodato, Andrew A Morris, Nicole Ulrick, Stanislav Kmoch, +Several Additional Authors

Neurology Faculty Publications

BACKGROUND: Mutations in the RMND1 (Required for Meiotic Nuclear Division protein 1) gene have recently been linked to infantile onset mitochondrial disease characterised by multiple mitochondrial respiratory chain defects.

METHODS: We summarised the clinical, biochemical and molecular genetic investigation of an international cohort of affected individuals with RMND1 mutations. In addition, we reviewed all the previously published cases to determine the genotype-phenotype correlates and performed survival analysis to identify prognostic factors.

RESULTS: We identified 14 new cases from 11 pedigrees that harbour recessive RMND1 mutations, including 6 novel variants: c.533C>A, p.(Thr178Lys); c.565C>T, p.(Gln189*); c.631G>A, p.(Val211Met); c.1303C>T, …

College Of Public Health News, Georgia Southern University

College of Public Health: News & Publications

• Georgia Southern Student Chosen as Scholar

Optimal Control Analysis Of Ebola Disease With Control Strategies Of Quarantine And Vaccination, Muhammad Dure Ahmad, Muhammad Usman, Adnan Khan, Mudassar Imran

Mathematics Faculty Publications

The 2014 Ebola epidemic is the largest in history, affecting multiple countries in West Africa. Some isolated cases were also observed in other regions of the world.

Social Support And Depression Symptomatology Post Injury In Division 1 Athletes, Alyssa Catherine Tiedens

Dissertations and Theses

The way in which an athlete responds to the injury--emotionally, behaviorally, and cognitively--can significantly affect the athlete's mental health in a negative way if not handled appropriately. There are different forms of social support that are known to be helpful with coping during specific stages of injury. The purpose of this study was to examine the relationship between perceived levels of social support and depression symptomatology post injury in Division 1 collegiate athletes at Portland State University (PSU).

Participants were PSU student athletes (n=115). Variables: social support amount (SSQN), social support satisfaction (SSQS), and depression symptomatology (CESD-R) score. Selected injured …

Développement D’Un Nouveau Dispositif D’Échantillonnage Des Aérosols De Diisocyanate-4,4’ De Diphénylméthane (Mdi) Utilisé Lors De La Pulvérisation De Mousse Isolante, Silvia Puscasu, Simon Aubin, Yves Cloutier, Philippe Sarazin, Huu Van Tra, Sébastien Gagné

Rapports de recherche scientifique

La pulvérisation de produits à base de MDI est une pratique commune à laquelle s’adonnent de nombreux travailleurs. Un exemple d’application de produits à base de MDI est le revêtement de mousse isolante commercial et résidentiel. Durant l’application de ce type de produit, les travailleurs sont exposés aux aérosols de MDI. Le MDI est un produit chimique reconnu comme étant un agent sensibilisant pouvant provoquer l’asthme professionnel. Afin de minimiser l’exposition des travailleurs au MDI, une surveillance environnementale doit être réalisée en milieu de travail afin de cartographier les zones contenant du MDI résiduel et de déterminer les secteurs et …

The Importance Of Data Quality In Using Health Information Exchange (Hie) Networks To Improve Health Outcomes: Case Study Of A Hie Extracted Dataset Of Patients With Congestive Heart Failure Participating In A Regional Hie, Marie-Astrid L. Cartron-Mizeracki

Theses and Dissertations

Expenditures on health information technology (HIT) for healthcare organizations are growing exponentially and the value of it is the subject of criticism and skepticism. Because HIT is viewed as capable of improving major health care indicators, the government offers incentives to health care providers and organizations to implement solutions. However HIT implementation is still subject to numerous technical, financial and organizational barriers. Health Information Exchange (HIE) networks are examples of HIT implementations that have been shown to assist healthcare providers in exchanging data and facilitating patient care through the circulation of critical clinical information between health care organizations statewide and …

Does Reactance Against Cigarette Warning Labels Matter? Warning Label Responses And Downstream Smoking Cessation Amongst Adult Smokers In Australia, Canada, Mexico And The United States, Yoo Jin Cho, Jim Thrasher, Kamala Swayampakala, Hua-Hie Yong, Robert Mckeever, David Hammond, Dien Anshari, K. Michael Cummings, Ron Borland

Faculty Publications

Objective

Some researchers have raised concerns that pictorial health warning labels (HWLs) on cigarette packages may lead to message rejection and reduced effectiveness of HWL messages. This study aimed to determine how state reactance (i.e., negative affect due to perceived manipulation) in response to both pictorial and text-only HWLs is associated with other types of HWL responses and with subsequent cessation attempts.

Methods

Survey data were collected every 4 months between September 2013 and 2014 from online panels of adult smokers in Australia, Canada, Mexico, and the US were analyzed. Participants with at least one wave of follow-up were included …

Partnership In Action: A Case Study In Nursing Workforce And Leadership Development In East Africa, Sharon Brownie

School of Nursing & Midwifery, East Africa

Session presented on Saturday, July 23, 2016: East Africa suffers an inordinate burden of disease and does not have the numbers of suitably qualified nurses and midwives to address this challenge.' Focussed efforts in nursing workforce capacity building are needed to build capacity within nursing education, practice and leadership. An enhanced nursing and midwifery workforce is needed across all disciplines with development required at all levels including upgrade of the existing workforce, development of speciality qualifications and enhancement of leadership capacity.'This presentation involves a case study in which university private-public partnerships have successful contributed to nursing capacity enhancement of nursing …

Health Policy & Management News, Georgia Southern University

Health Policy & Community Health: News & Publications (2011-2018)

• Georgia Southern Student Chosen as Scholar

How To Impress: Coordinating A Large Video Data Set For A Collaborative Project, Noah-Kee Marks, Rita Dawod

DePaul Discoveries

Though many different research methods involve mass quantities of video/audio data, there is little discussion of best practices for organization, especially when the research is collaborative. The guidelines we provide here were created while conducting educational research on the IMPRESS project, an integrated metacognitive program for at risk STEM majors at Rochester Institute of Technology (RIT). Our hope is to encourage large-scale, collaborative research of qualitative video data by using our project as an example and providing enough information for readers to make a judgment on the efficacy of this process for their own projects.

In Search Of Exoplanets, Krzysztof J. Skwirut, Samuel Montag, Kayla Lynch, Justin A. Potvin

DePaul Discoveries

Using data archives containing radial-velocity and light intensity information for stars, the DePaul Astrophysics Working Group created MATLAB programs to read and analyze the data in hopes of detecting extrasolar planets. The codes were able to successfully create graphs and obtain orbital periods for potential planets which matched published results. Additional tests were then researched to be used in the future as to confirm new planets.

Comparison Of Soil Phosphorus Concentration In Farm Restored And Reference Wetlands In Lake County, Il, Catherine L. Pease

DePaul Discoveries

The soil in the Midwest is fertile for agriculture use and therefore a lot of the wetlands have been turned into farmland. Wetlands can act as a sink for excess nutrients such as phosphorus. In part due to their value for nutrient storage, restoration of wetlands has become more frequent, including restoration of wetlands on former farmland. I am interested in phosphorus and the potential of wetlands to either store or release phosphorus. I compared differences in soil reactive phosphorus of restored and reference wetlands. This study compares Prairie Wolf Slough (PWS), a restored wetland, to two reference wetlands, both …

Decomposition Of Horse Manure (As A Surrogate For Human Feces) In Three Soil Media And The Implications Of Manure Leachate For The Germination Of Radish Seeds, Edwin J. Castaneda, Caitlin Vaughn

DePaul Discoveries

In this microcosm study we examined the decomposition of horse manure in three substrates: potting soil, wood mulch, and sand. Microcosms consisted of a sample of horse manure placed in a small leachable chamber, containing one of the three substrates. Mulch promoted the greatest mass loss. Leachate collected by irrigating each microcosm with distilled water was used to germinate radish seeds. Only the leachate from microcosms in which manure decomposed in potting soil promoted greater radish radicle growth compared to the controls in which no manure was placed. The implications of these results for the design of a soil-based decomposing …

Motivation For Change In Heroin And Opiate Users, Andrew W. Peterson, Sarah Callahan, Leonard A. Jason

DePaul Discoveries

Opioid and heroin abuse is a continuing problem in the United States that has been increasing dramatically since 2000. Common treatment programs tend to use methadone and behavioral therapies that do not focus on motivational factors despite the research suggesting it is an important element to treatment retention and sustained abstinence. Motivation for the purposes of this study is defined as an individual’s inner reasons for change. The current study focused on differences in motivation for change among different substance abusers. We found that opiate and heroin abusers had higher motivational scores in comparison to other substance abusers. These results …

The Role Of Infectious And Stress-Related Onsets In Myalgic Encephalomyelitis And Chronic Fatigue Syndrome Symptomatology And Functioning, Andrew R. Devendorf, Abigail A. Brown, Leonard A. Jason

DePaul Discoveries

This study examined how the mode of onset for myalgic encephalomyelitis and chronic fatigue syndrome (ME and CFS) impacts patients’ presenting symptomatology. Specifically, this study investigated the differences between the most commonly reported ME and CFS onsets: infectious, stress-related, and a combined infectious and stress-related onset (referred to as ‘combined onset’). Three patient samples were combined and utilized. All participants met Fukuda et al. (1994) criteria and self-reported their illness onset. Analyses showed the infectious group reported the most impairment for general health functioning—which relates to the susceptibility of getting or feeling sick—in comparison to the stress-related group. Meanwhile, both …

Effects Of Quercetin On Blood Pressure: A Systematic Review And Meta-Analysis Of Randomized Controlled Trials, Maria-Corina Serban, Alberto Zanchetti, George Howard, Diana Antal, Wilbert S. Aronow, Lipid And Blood Pressure Meta-Analysis Collaboration (Lbpmc) Group

NYMC Faculty Publications

BACKGROUND: Quercetin, the most abundant dietary flavonol, has antioxidant effects in cardiovascular disease, but the evidence regarding its effects on blood pressure (BP) has not been conclusive. We assessed the impact of quercetin on BP through a systematic review and meta-analysis of available randomized controlled trials.

METHODS AND RESULTS: We searched PUBMED, Cochrane Library, Scopus, and EMBASE up to January 31, 2015 to identify placebo-controlled randomized controlled trials investigating the effect of quercetin on BP. Meta-analysis was performed using either a fixed-effects or random-effect model according to I(2) statistic. Effect size was expressed as weighted mean difference (WMD) and 95% …

Experimental Data Extraction And In Silico Prediction Of The Estrogenic Activity Of Renewable Replacements For Bisphenol A., Huixiao Hong, Benjamin G Harvey, Giuseppe R Palmese, Joseph F. Stanzione Iii, Hui Wen Ng, Sugunadevi Sakkiah, Weida Tong, Joshua M Sadler

Henry M. Rowan College of Engineering Departmental Research

Bisphenol A (BPA) is a ubiquitous compound used in polymer manufacturing for a wide array of applications; however, increasing evidence has shown that BPA causes significant endocrine disruption and this has raised public concerns over safety and exposure limits. The use of renewable materials as polymer feedstocks provides an opportunity to develop replacement compounds for BPA that are sustainable and exhibit unique properties due to their diverse structures. As new bio-based materials are developed and tested, it is important to consider the impacts of both monomers and polymers on human health. Molecular docking simulations using the Estrogenic Activity Database in …

Sustained Release Of Topical Anesthetics, Michael Jay

Pharmaceutical Sciences Faculty Patents

A composition and method to alleviate oral mucosal discomfort and irritation in an orthodontic patient. A wax matrix containing less that 15% analgesic/anesthetic agent such as benzocaine and excipients enhanced and extended release of the analgesic/anesthetic agent compared to known art formulations. The composition exhibited desirable aesthetic properties, was easy to apply, and the relatively lower concentration of active agent provided enhanced safety.

Hepatitis C Virus Frameshift/Alternate Reading Frame Protein Suppresses Interferon Responses Mediated By Pattern Recognition Receptor Retinoic-Acid-Inducible Gene-I, Seung Bum Park, Scott Seronello, Wasima Mayer, David M. Ojcius

All Dugoni School of Dentistry Faculty Articles

Hepatitis C virus (HCV) actively evades host interferon (IFN) responses but the mechanisms of how it does so are not completely understood. In this study, we present evidence for an HCV factor that contributes to the suppression of retinoic-acid-inducible gene-I (RIG-I)-mediated IFN induction. Expression of frameshift/alternate reading frame protein (F/ARFP) from HCV -2/+1 frame in Huh7 hepatoma cells suppressed type I IFN responses stimulated by HCV RNA pathogen-associated molecular pattern (PAMP) and poly(IC). The suppression occurred independently of other HCV factors; and activation of interferon stimulated genes, TNFα, IFN-λ1, and IFN-λ2/3 was likewise suppressed by HCV F/ARFP. Point mutations in …

The Genetic Landscape Of Dural Marginal Zone Lymphomas, Karthik A. Ganapathi, Vaidehi Jobanputra, Fabio Iwamoto, Pallavi Khattar, Elaine S. Jaffe, Mahesh M. Mansukhani, Govind Bhagat

NYMC Faculty Publications

The dura is a rare site of involvement by marginal zone lymphoma (MZL) and the biology of dural MZL is not well understood. We performed genome-wide DNA copy number and targeted mutational analysis of 14 dural MZL to determine the genetic landscape of this entity. Monoallelic and biallelic inactivation of TNFAIP3 by mutation (n=5) or loss (n=1) was observed in 6/9 (67%) dural MZL exhibiting plasmacytic differentiation, including 3 IgG4+ cases. In contrast, activating NOTCH2 mutations were detected in 4/5 (80%) dural MZL displaying variable monocytoid morphology. Inactivating TBL1XR1 mutations were identified in all NOTCH2 mutated cases. Recurrent mutations in …

Development Roots Of Mindfulness: An Attachment Based Perspective On The Origins Of Mindfulness And Reflective Functioning Through The Parent-Child Relationship, A Mixed-Methods Analysis, Ashley N. Morris

Morehead State Theses and Dissertations

A thesis presented to the faculty of the College of Science Morehead State University in partial fulfillment of the requirements for the Degree Master of Science by Ashley N. Morris July 11, 2016.

Cellular Minichromosome Maintenance Complex Component 5 (Mcm5) Is Incorporated Into Hiv-1 Virions And Modulates Viral Replication In The Newly Infected Cells., Steven Santos, Yuri Obukhov, Sergei Nekhai, Tatiana Pushkarsky, Beda Brichacek, Michael Bukrinsky, Sergey Iordanskiy

Microbiology, Immunology, and Tropical Medicine Faculty Publications

The post-entry events of HIV-1 infection occur within reverse transcription complexes derived from the viral cores entering the target cell. HIV-1 cores contain host proteins incorporated from virus-producing cells. In this report, we show that MCM5, a subunit of the hexameric minichromosome maintenance (MCM) DNA helicase complex, associates with Gag polyprotein and is incorporated into HIV-1 virions. The progeny virions depleted of MCM5 demonstrated reduced reverse transcription in newly infected cells, but integration and subsequent replication steps were not affected. Interestingly, increased packaging of MCM5 into the virions also led to reduced reverse transcription, but here viral replication was impaired. …

Ada News - 07/11/2016, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

What's Happening: July 11, 2016, Maine Medical Center

What's Happening

No abstract provided.

Intranasal Fentanyl In Pediatric Patients Undergoing Bilateral Myringotomy And Tympanostomy Tube Placement, Ivan Martic

Nursing Capstones

No abstract provided.

Compassion Fatigue In Mental Health Nurses: Understanding Cause, Effect, Prevention And Intervention, Anne Funk

Nursing Capstones

No abstract provided.

Adolescent Healthcare Brokering: Prevalence, Experience, Impact, And Opportunities, Jennifer R. Banas, Lisa C. Wallis, James W. Ball, Sarah Gershon

Health Sciences and Physical Education Faculty Publications

BACKGROUND: Limited health literacy disproportionately affects those with limited English proficiency (LEP). Parents with LEP might rely on their adolescent children to interpret health information. We call this adolescent health care brokering. This study uncovers the prevalence of brokering, kinds of tasks, emotional and academic impact, and desired support.

METHODS: We invited 165 students from health classes (in a community in which 29.8% are foreign-born and 53.4% speak another language at home) to complete a survey. We used IBM SPSS to calculate descriptive statistics.

RESULTS: Of the 159 who received parental consent and assented, 54.1% (n=86) assist with healthcare …