Medicine and Health Sciences Commons^™

Combating Compassion Fatigue By Creating Moments That Matter, Nicole Reimer Bsn, Rn, Ocn

Patient Care Services / Nursing

No abstract provided.

A Non-Invasive Method To Evaluate Gastrointestinal Transit Behaviour In Rat, Geoffrey M. Bove

Biomedical Sciences Faculty Publications

Introduction: Many factors alter gastrointestinal transit. Animal models are useful for preclinical studies of gastrointestinal transit, but terminal methods do not allow later study, and stressful assessment methods will likely alter the transit of the animal. To overcome these factors, we developed a new method to assay rat total gastrointestinal transit.

Methods: Standard plastic cages with their bottoms cut off were placed on wire mesh floors. Custom apparatuses were built to contain fecal pellets as they fell through the floors. Webcams connected to a computer running a security program were placed to image the pellets at regular intervals. Custom food …

Improving Patient Satisfaction After Primary Total Knee Arthroplasty Using Nurse Practitioner-Driven Preoperative Education, Jennifer A. White

Doctor of Nursing Practice Scholarly Projects

Total joint arthroplasty is an undisputed option for relieving pain and improving the function of an arthritic joint. The number of patients undergoing total knee arthroplasty (TKA) annually is expected to increase by 600% in the next two decades (Lau, Gandhi, Mahomed, & Mahomed, 2012).

Current research shows that while 81-89% of patients who have had a TKA are satisfied postoperatively, there is room to improve patient satisfaction by providing further education preoperatively. While research cannot agree on a single, specific variable that influences patient dissatisfaction, a review of the literature shows that patients repeatedly note their “unmet expectations” as …

Lgbt Advocacy: One Leader's Journey Through Fear To Transcendence, Paula Suffrins

Theses and Graduate Projects

The LGBT population experiences healthcare disparities at higher rates than their heterosexual counterparts. Fear among this population prevents them from seeking health care. Nurses can be influential in addressing this fear and decreasing healthcare disparities within the LGBT population. However, LGBT content offered in nursing programs is not adequately preparing students to care for this specific population in a culturally sensitive manner. Healthcare organizations lack LGBT content in orientation programs as well. Transformational nursing leaders can initiate and support the effort to create a safe and welcoming environment for the LGBT population where healthcare can be delivered by culturally sensitive …

Fda Approves 18 New Molecular Entities/Biologics, Rodney Richmond

Faculty Research ​and Publications

No abstract provided.

Closed Head Injury In An Age-Related Alzheimer Mouse Model Leads To An Altered Neuroinflammatory Response And Persistent Cognitive Impairment, Scott J. Webster, Linda J. Van Eldik, D. Martin Watterson, Adam D. Bachstetter

Sanders-Brown Center on Aging Faculty Publications

Epidemiological studies have associated increased risk of Alzheimer's disease (AD)-related clinical symptoms with a medical history of head injury. Currently, little is known about pathophysiology mechanisms linked to this association. Persistent neuroinflammation is one outcome observed in patients after a single head injury. Neuroinflammation is also present early in relevant brain regions during AD pathology progression. In addition, previous mechanistic studies in animal models link neuroinflammation as a contributor to neuropathology and cognitive impairment in traumatic brain injury (TBI) or AD-related models. Therefore, we explored the potential interplay of neuroinflammatory responses in TBI and AD by analysis of the temporal …

Assessment Of Empathy Scores In A Pharmacy Professional Nutrition Support Elective Course, Megan M. Mayhew

Undergraduate Honors Thesis Collection

Background: Clinical empathy may be defined as "the ability to listen to, understand, sympathize with, and provide support to another individual." Empathy has been shown to influence patient satisfaction, adherence, and improve clinical outcomes. Teaching empathy skills in the classroom and clinical setting is imperative to allow students to develop and enhance their communication with patients.

Study Objective: To evaluate two empathy projects in the RX 618 Nutrition Support Professional Elective to identify if the projects are effective in improving pharmacy students' knowledge of empathy.

Methods: The study objective was met using a prospective cohort survey based study. An interactive …

Synthesis Of Β-Triphosphotriester Pronucleotides, Yousef A. Beni, Chandravanu Dash, Keykavous Parang

Pharmacy Faculty Articles and Research

Dinucleoside phosphorochloridite were synthesized from phosphorus trichloride and three nucleoside analogues, 3-fluoro-2,3-dideoxythymidine (FLT), 2',3'-dideoxy-5-fluoro-3'- thiacytidine (FTC), and 2',3'-dideoxy-3'-thiacytidine (3TC), in a multistep synthesis. Polymerbound N-Boc p-acetoxybenzyl 5¢-O-2¢-deoxythymidine was reacted with dinucleoside phosphorochloridite in the presence of 2,6-lutidine, followed by the reaction with dodecyl alcohol and 5-(ethylthio)-1H-tetrazole, oxidation with tert-butyl hydroperoxide, and acidic cleavage, respectively, to afford the b-triphosphotriester derivatives containing three different nucleosides.

Conversational Scaffolding With Couples With An Aphasic Partner, Mary Jo Bissmeyer

Undergraduate Honors Thesis Collection

Aphasia is an acquired language disorder experienced by approximately one million Americans today, many recovering from stroke or traumatic brain injury. Traditional therapy has focused solely on regaining specific linguistic skills, including auditory comprehension, speech, reading, and/or writing. Conversation partner training is a newer trend in aphasia intervention that has emerged thanks to an increasingly social model of disability and the pressure to deliver meaningful and cost effective health services. It fits nicely with the Life Participation Approach to Aphasia, which encourages clinicians to help individuals with aphasia and their families set and meet their own goals for therapy, which …

Evaluating The Non-Evidence Based Practice Of Rounding Serum Creatinine In The Elderly And The Impact On Medication Dosing, Kelly Lynn Roden

Undergraduate Honors Thesis Collection

Background: The Cockcroft and Gault equation is widely accepted in practice as the most appropriate way to calculate an estimated creatinine clearance. Geriatric patients often present with reduced muscle mass, and therefore lower creatinine production, due to normal changes in body composition associated with aging. Because serum creatinine and creatinine clearance are inversely proportional using the Cockcroft and Gault equation, a lower serum creatinine may falsely overestimate renal function in the elderly population. Rounding to a normal serum creatinine is believed by some practitioners to prevent over estimation of creatinine clearance and renal function.

Objective: The objective of this study …

Role Of Il-16 In Cd4(+) T Cell-Mediated Regulation Of Relapsing Multiple Sclerosis, Dusanka S. Skundric, William W. Cruikshank, Jelena Drulovic

Neurology Faculty Publications

In an important article published in Nature Medicine, Liu and colleagues described a novel CD4⁺ FoxA1⁺ regulatory T (Treg) cell population as distinct regulators of relapsing-remitting multiple sclerosis (RRMS) and experimental autoimmune encephalomyelitis (EAE). CD4⁺ FoxA1⁺ Treg cells appear as key regulators of responsiveness to therapy with interferon beta (IFN-β) in RRMS patients. Data indicate that CD4⁺ FoxA1⁺ FOXP3⁻ Treg cells develop within the central nervous system (CNS), and a potential of cerebellar granule neurons (CGN) in generation of CD4⁺ FoxA1⁺ PD-L1^hiFOXP3⁻ Treg cells from encephalitogenic CD4^{+ …}

Molecular Dyes Used For Surgical Specimen Margin Orientation Allow For Intraoperative Optical Assessment During Breast Conserving Surgery, David M. Mcclatchy, Venkataramanan Krishnaswamy, Stephen C. Kanick, Jonathan T. Elliott, Wendy A. Wells, Richard J. Barth Jr., Keith D. Paulsen, Brian W. Pogue

Dartmouth Scholarship

A variety of optical techniques utilizing near-infrared (NIR) light are being proposed for intraoperative breast tumor margin assessment. However, immediately following a lumpectomy excision, the margins are inked, which preserves the orientation of the specimen but prevents optical interrogation of the tissue margins. Here, a workflow is proposed that allows for both NIR optical assessment following full specimen marking using molecular dyes which have negligible absorption and scattering in the NIR. The effect of standard surgical inks in contrast to molecular dyes for an NIR signal is shown. Further, the proposed workflow is demonstrated with full specimen intraoperative imaging on …

The Effects Of Adderall On Maternal And Fetal Health, Alyson Brady

Honors Theses

Information available for woman prescribed Adderall to treat ADHD and the effects that it may have on her fetus is limited. However, Adderall and methamphetamine have similar pharmacological and addictive qualities. This paper is concerned with whether there is an adequate approach to treatment that balances the needs of the mother and the fetus. With Adderall use becoming more prevalent, it is essential that society is aware of the physiology and pharmacology of this drug, as well as, the need for more research on this subject to be produced.

Exercise Ameliorates High Fat Diet Induced Cardiac Dysfunction By Increasing Interleukin 10., Varun Kesherwani, Vishalakshi Chavali, Bryan T. Hackfort, Suresh C. Tyagi, Paras K. Mishra

Journal Articles: Cellular & Integrative Physiology

Increasing evidence suggests that a sedentary lifestyle and a high fat diet (HFD) leads to cardiomyopathy. Moderate exercise ameliorates cardiac dysfunction, however underlying molecular mechanisms are poorly understood. Increased inflammation due to induction of pro-inflammatory cytokine such as tumor necrosis factor-alpha (TNF-α) and attenuation of anti-inflammatory cytokine such as interleukin 10 (IL-10) contributes to cardiac dysfunction in obese and diabetics. We hypothesized that exercise training ameliorates HFD- induced cardiac dysfunction by mitigating obesity and inflammation through upregulation of IL-10 and downregulation of TNF-α. To test this hypothesis, 8 week old, female C57BL/6J mice were fed with HFD and exercised (swimming …

The Elements Of Healing And Wellness Post Diagnosis Of Cancer: A Review Of The Literature And A Personal Account, Tiffany Bystra

Honors Theses

Being diagnosed with cancer is an earth-shaking experience that can break even the most strong and stable of individuals. Thoughts of uncertainty and anxiety are commonly experienced for those having been diagnosed, and when one’s health is compromised, nothing else seems to matter except becoming healthy and well again. This honors thesis deeply investigates my personal experiences being a recent cancer survivor in conjunction with reviewing the research and literature to investigate how one can promote their healing and wellness through holistic means despite going through medical treatments that are physically, emotionally, and spiritually taxing on every level. A thorough …

“Cpr” For Cpoe Implementation, Karen Marsiglio Rn, Bsn, Marguerite Petsuck Rn, Bsn

Patient Care Services / Nursing

No abstract provided.

Traveling Exhibit Native Voices: Native Peoples’ Concepts Of Health And Illness, Patricia Bradley, Laura J. Hall, Gale Hannigan

Posters and Presentations

This exhibit, organized by the National Library of Medicine and hosted at UNM, explores the intersections of health, illness, and culture among Native American, Alaska Native, and Native Hawaiian communities. Through oral histories, healers, elders, and other key figures recount the impact of epidemics, land loss, and cultural disruption on Native health. The exhibit presents an inspiring narrative of resilience, endurance, and self-determination. Curated locally by Patricia Bradley, Laura J. Hall, and Gale Hannigan, it was displayed at the Domenici Center for Health Sciences Education. April 22, 2015 - October 18, 2015

Strangulation Assessment, Evidence Collection, And Documentation Guidelines For Forensic Nurse Examiners: A Pilot Project, Sally Sturgeon

Graduate Theses, Dissertations, and Capstones

Accurate and thorough physical assessment, with accompanying documentation, are essential components for appropriate legal intervention for victims in all strangulation cases. There is a need for this strangulation assessment, evidence collection, and documentation protocol. Forensic nurse examiners who work with strangulation victims need to be sure that their assessment, evidence collection, and documentation are complete, accurate, and consistent to help ensure perpetrator accountability.

Development And Evaluation Of A Skin-To-Skin In The Operating Room Protocol, Sara Lang

Nursing Masters

This article describes the development and evaluation of a skin-to-skin in the operating room protocol. A protocol would standardize the practice of skin-to-skin in the operating room and provide a resource for the team members involved to use. The protocol evaluation and feedback was obtained from several members of the health care team, including an obstetrician, an anesthesiologist, a pediatrician, a pediatric nurse practitioner, and nurses who work as a labor nurses, baby delivery nurses, and/or lactation nurses.

Breastfeeding Education For Adolescent Mothers, Emily Osgood

Nursing Masters

Purpose: The WHO, AAP, and DHHS recommend exclusive breastfeeding for the first six months of life and continued supplementary breastfeeding until two years of age. Breastfeeding initiation and duration rates are low worldwide, particularly among the adolescent population. The national initiation rate for teen mothers is only 43%, as compared to their adult counterparts at 73.9%; and at six months, only 19% of those teenagers were still breastfeeding.

The objective of this research project is to develop a prenatal educational program geared toward the adolescent population at a local community hospital.

Study Design and Methods: This breastfeeding educational program was …

The Effect Of Education On Compassion Fatigue As Experienced By Staff Nurses, Kathryn L. Zehr

Evidence-Based Practice Project Reports

Historically, nursing has been perceived as a highly rewarding profession. Yet, due to the increasing complexity of today’s healthcare, nurses are faced with greater challenges in their work environments. Registered nurses who work in tertiary care settings are exposed to disturbing patient situations including trauma, death, abuse, or chronic disease. Joinson (1992) described this experience as compassion fatigue and symptoms include headaches, short attention span, or fatigue. A review of literature has identified that nurses should be educated about risk factors and coping strategies to combat compassion fatigue. Guided by the Model for Evidence-Based Practice Change and Jean Watson’s Theory …

2015 April 21 - Medical Student Education Committee Minutes, Medical Student Education Committee, East Tennessee State University

Medical Student Education Committee Minutes

No abstract provided.

Cross-Cultural And Inter-Professional Knowledge Translation Of Developmentally Supportive Care In An Indian Nicu, Amy Carroll, Otd, Otr/L, Susan Toth-Cohen, Phd, Otr/L

Department of Occupational Therapy Posters and Presentations

Synopsis:

A cross-cultural, and inter-professional NICU Team, including an American OT, used knowledge translation (KT) frameworks to apply current global evidence in developmentally supportive care in ways that were useful, cost effective, and meaningful to the families and staff in their tertiary care NICU setting in Gurgaon, India. The team used Pre & Post videotaping of routine care and procedures to measure the change in practice.

Objectives

1. Increase NICU nurses’ use of DSC during routine care and procedures

2. Decrease the use of non-supportive behaviors

Embedding Mindfulness Practice In Entry-Level Occupational Therapy Education Program: Experiences And Outcomes, Mary Muhlenhaupt, Otd, Otr/L, Faota, Shelly Wallock, Dr.P.H., Otr/L

Department of Occupational Therapy Posters and Presentations

Objective:

To embed mindfulness practice into an entry-level occupational therapy curriculum and assess outcomes to reduce student stress and promote well-being.

Diagnosis And Management Of Hyponatremia In Patients With Aneurysmal Subarachnoid Hemorrhage, Neena I. Marupudi, Sandeep Mittal

Neurosurgery Faculty Publications

Hyponatremia is the most common, clinically-significant electrolyte abnormality seen in patients with aneurysmal subarachnoid hemorrhage. Controversy continues to exist regarding both the cause and treatment of hyponatremia in this patient population. Lack of timely diagnosis and/or providing inadequate or inappropriate treatment can increase the risk of morbidity and mortality. We review recent literature on hyponatremia in subarachnoid hemorrhage and present currently recommended protocols for diagnosis and management.

Drug-Drug Interactions Among Hepatitis C Virus (Hcv) And Human Immunodeficiency Virus (Hiv) Medications, Kirpal Kaur, Mona A. Gandhi, Judianne Slish

Doctoral External Publications

One-fourth of individuals diagnosed with the human immunodeficiency virus concomitantly have the hepatitis C virus infection. Since the discovery of highly active antiretroviral therapy, liver complications have become the leading cause of morbidity and mortality in HIV-HCV coinfected individuals. Optimal treatment in this patient population is critical, as coinfection has been linked to deterioration of both disease states. The objective of this review article is to highlight the current literature on drug-drug interactions between HIV and HCV treatments. The management of the treatment of coinfection patients has been covered extensively in numerous other publications.

Optimisation De Saturisk, L’Outil De Calcul Du Temps De Service Des Cartouches De Protection Respiratoire Contre Les Vapeurs Organiques, Ludovic Tuduri, Florence Janvier, Yves Cloutier, Josée Poulin, Daniel Cossement, Daniel Drolet, Jaime Lara

Rapports de recherche scientifique

L’exposition des travailleurs aux solvants, ou plus largement aux vapeurs organiques, doit être maîtrisée sinon maintenue en deçà des valeurs limites réglementaires. Lorsque l’ensemble des mesures administratives, d’ingénierie et de protection collective ne permet pas d’atteindre des niveaux d’exposition sans danger pour la santé, les travailleurs concernés doivent être équipés d’appareils de protection respiratoire (APR). En l’absence de situations de danger immédiat pour la vie et la santé (DIVS), les APR équipés de cartouches de filtration à base de charbon activé sont utilisés contre les vapeurs organiques. Se pose alors la question du temps de service de ces cartouches. Parmi …

Lymphedema In A Hypertrophic Scar: Treatment With Fractional Co2 Laser, Sigrid A. Blome-Eberwein Md

Department of Surgery

No abstract provided.

Variations In Public Health Governance, Jeffery A. Jones, Ankit Bangar, Patrick Chang, Yelena N. Tarasenko

Epidemiology: Faculty Presentations (2000-2018)

Background: Studies of public health departments have found mixed results regarding the relevance of governance through local boards of health (LBOHs). Some studies find that LBOHs can be an important component in higher performance by local health departments. Other analyses, however, find no advantage for local health departments having or not having a LBOH. The hypothesis was that a typology of LBOHs nationwide can define different types of LBOHs based on their powers and responsibilities.

Methods: Using national profile sample data from the National Association of Local Boards of Health, LBOHs were categorized using 34 variables based on four domains …

Integration Of Resistant Starch In Homemade Pasta, Anja Grommons

Honors Theses

In response to raised consumer awareness of health and well-being many manufacturers are transforming popular food items into functional foods with higher nutritional value. Typical pasta recipes consist of all purpose (AP) flour and/ or semolina flour which contain minimal nutritional value. Resistant Starch (RS) contains a high fiber profile accompanied by many physiological benefits. This study investigated the effect of partial substitution of RS for semolina and AP flours on functional, nutritional, and sensory properties of handmade pasta. RS was substituted for semolina and AP flours at levels of 20% and 30% substitution. As the amount of RS in …