Medicine and Health Sciences Commons^™

Southern Chivalry: Perception Of Health & Environmental Justice In A Small Southern Neighborhood, Brian S. Brijbag

USF Tampa Graduate Theses and Dissertations

This paper analyzes heath risk and how it is communicated to, and understood within, a predominantly African American neighborhood in central Florida. Residents accuse the county department of public works of purposeful contamination and discrimination over a period of 30 years. I raise the questions of how risk is perceived and what roles race or class may play. I also developed a model for risk communication that includes all stakeholders. Finally, I expand the conversation of health disparities to include issues of widening gaps in perceptions of health.

This was examined by looking at the following:

1. The lack of …

The Characterization Of The Neuropathological Consequences Of Plac1 Ablation In A Mutant Mouse Model, Jacob Robert Bourgeois

USF Tampa Graduate Theses and Dissertations

Placenta-specific 1 (Plac1) is an X-linked gene that is essential for normal placental development. Previous studies have shown that Plac1 is also expressed in the fetal brain and paternally imprinted. Its expression in the fetal brain is markedly downregulated immediately after birth. Plac1 ablation predisposes Plac1-null males and X^m-X Hets (inactive maternal allele) to an increased risk of developing lethal postnatal hydrocephalus suggesting a functional role for Plac1 during embryonic development. The objective of this study was to characterize the effect of Plac1 on brain development and postnatal function. In order to address this, a …

Associations Between Social Determinants Of Health And Adolescent Pregnancy: An Analysis Of Data From The National Longitudinal Study Of Adolescent To Adult Health, Sarah Britney Maness

USF Tampa Graduate Theses and Dissertations

This dissertation study utilized the National Longitudinal Study of Adolescent to Adult Health to analyze empirical relationships between social determinants of health and adolescent pregnancy. Although rates of adolescent pregnancy are at an all-time low in the United States, disparities persist. Examining relationships between the social determinants of health and adolescent pregnancy provides support for funding and interventions that expand on the current focus of individual and interpersonal level factors. Based on the Healthy People 2020 Social Determinants of Health Framework, proxy measures for social determinants of health were identified within the Add Health study and analyzed in relationship with …

Sexual Functioning And Body Image In Younger Breast Cancer Survivors, Carly Lynn Paterson

USF Tampa Graduate Theses and Dissertations

Younger breast cancer survivors often report problems related to sexuality following surgical and adjuvant treatment that often lead to sexual distress and body image distress. This research was conducted as an exploratory study within a larger R01 trial with the purpose to evaluate sexual distress and body image related-distress in younger women with breast cancer and to examine the extent to which the Mindfulness-Based Stress Reduction-Breast Cancer (MBSR(BC)) was efficacious in improving distress related to sexuality, i.e. sexual distress and body image related-distress. The aims of this study were to: 1) evaluate the efficacy of the MBSR(BC) program in improving …

Endocrine-Disrupting Compounds: Measurement In Tampa Bay, Removal From Sewage And Development Of An Estrogen Receptor Model, Monica Mion Cook

USF Tampa Graduate Theses and Dissertations

The significance of endocrine-disrupting compounds (EDCs) in the environment has only recently come to the forefront of scientific research, policy debates, water utilities management and public awareness. EDCs have the ability to interfere with the normal functioning of the endocrine system of humans and other animals. Numerous chemicals are included in the class of compounds known as EDCs, and exposure is widespread. These compounds are found in a variety of environmental matrices (e.g., marine and freshwater systems, sediment, soil), transported there primarily through sewage effluent discharge and recycling of sewage sludge for topical fertilizer use. This transport to the environment …

Pathogenic Policy: Health-Related Consequences Of Immigrant Policing In Atlanta, Ga, Nolan Sean Kline

USF Tampa Graduate Theses and Dissertations

Multilayered immigration enforcement regimes comprising state and federal statutes and local police practices demand research on their social and health-related consequences. This dissertation explores the multiple impacts of immigrant policing: sets of laws and police activities that make undocumented immigrants more visible to authorities and increase their risk of deportation. Examining immigrant policing through a multi-sited framework and drawing from principles of engaged anthropology, findings from this dissertation suggest how immigrant policing impacts undocumented immigrants' overall wellbeing, health providers' professional practice, and reveals troubles with safety net medical care. Interviews and participant observation experiences suggest how immigrant policing perpetuates a …

Altered Intraerythrocytic Development Phenotypes Of Artemisinin-Resistant Plasmodium Falciparum Confer A Fitness Advantage, Amanda Hott

USF Tampa Graduate Theses and Dissertations

Resistance to artemisinin combination therapies (ACTs) has emerged in southeast Asia threatening the most widely used treatment against antimalarial-resistant Plasmodium falciparum worldwide. Artemisinin resistance has been associated with a reduced rate of parasite clearance following treatment with an ACT and is attributed to increased survival of ring-stage parasites. Single nucleotide polymorphisms (SNPs) in kelch gene (K13) has been associated with delayed in vivo clearance half-life of artemisinin-resistant P. falciparum and is the only known molecular marker of resistance. The absence of reliable in vitro phenotypes for artemisinin resistance has limited our understanding of the resistance mechanism(s) and fitness costs, therefore …

Metal Organic Frameworks (Mofs) And Porous Organic Polymers (Pops) For Heterogeneous Asymmetric Catalysis, Youngran Ji

USF Tampa Graduate Theses and Dissertations

The administration of enantiopure drugs brings advantages such as improved efficacy, more predictable pharmacokinetics and reduced toxicity from the point of view of the pharmaceutical area.[1] For this reason, a tremendous amount of supply and demand for enantiomeric pure compounds has been shown not only in market, but industry and academia.[^2-4] According to the industry publication Genetic Engineering and Biotechnology News (GEN) in 2014, 22 billion dollars were accounted for enantiopure form of drugs such as Sovaldi® (Sofosbuvir), Crestor® (Rosuvastatin), and Advair® (fluticasone/salmeterol).

The fact that one enantiomer can be pharmacologically effective whereas the other enantiomer can be …

Hpv Vaccine Decision-Making Among Male Sexual Minorities: An Integrative Theoretical Framework For Vaccine Promotion, Christopher W. Wheldon

USF Tampa Graduate Theses and Dissertations

Men who have sex with men (MSM) are at increased risk of anal cancer as a result of anal HPV infection. Routine HPV vaccination is recommended for all MSM up through age 26; however, vaccine uptake among this population is low. The Integrative Model of Behavioral Prediction (IM) was used to identify, describe, and explain psychosocial factors related to HPV vaccine decision-making for young MSM. A sequential mixed-methods approach consisting of semi-structured interviews, a quantitative survey, and a qualitative open-ended survey was used to address the following aims: (1) Determine salient outcome, normative, efficacy, and control beliefs related to HPV-vaccination …

Reduced Cardiovascular Capacity And Resting Metabolic Rate In Men With Prostate Cancer Undergoing Androgen Deprivation: A Comprehensive Cross-Sectional Investigation, Bradley Wall, Daniel A. Galvao, Naeem Fatehee, Dennis Taaffe, Nigel Spry, David Joseph, Robert Newton

Research outputs 2014 to 2021

Objectives. To investigate if androgen deprivation therapy exposure is associated with additional risk factors for cardiovascular disease and metabolic treatment-related toxicities. Methods. One hundred and seven men (42-89 years) with prostate cancer undergoing androgen deprivation therapy completed a maximal graded objective exercise test to determine maximal oxygen uptake, assessments for resting metabolic rate, body composition, blood pressure and arterial stiffness, and blood biomarker analysis. A cross-sectional analysis was undertaken to investigate the potential impact of therapy exposure with participants stratified into two groups according to duration of androgen deprivation therapy (≥3 months). Results. Maximal oxygen uptake (26.1 ± 6.0 mL/kg/min …

Circulating Tumor Dna To Monitor Treatment Response And Detect Acquired Resistance In Patients With Metastatic Melanoma, Elin S. Gray, Helen Rizos, Anna L. Reid, Suzanah Boyd, Michelle Pereira, Johnny Lo, Varsha Tembe, James Freeman, Jenny Lee, Richard Scolyer, Kelvin Siew, Chris Lomma, Adam Cooper, Muhammad Khattak, Tarek Meniawy, Georgina Long, Matteo Carlino, Michael Millward, Mel R. Ziman

Research outputs 2014 to 2021

Repeat tumor biopsies to study genomic changes during therapy are difficult, invasive and data are confounded by tumoral heterogeneity. The analysis of circulating tumor DNA (ctDNA) can provide a non-invasive approach to assess prognosis and the genetic evolution of tumors in response to therapy. Mutation-specific droplet digital PCR was used to measure plasma concentrations of oncogenic BRAF and NRAS variants in 48 patients with advanced metastatic melanoma prior to treatment with targeted therapies (vemurafenib, dabrafenib or dabrafenib/trametinib combination) or immunotherapies (ipilimumab, nivolumab or pembrolizumab). Baseline ctDNA levels were evaluated relative to treatment response and progression-free survival (PFS). Tumor-associated ctDNA was …

Maternal Fish Oil Supplementation In Pregnancy: A 12 Year Follow-Up Of A Randomised Controlled Test, Suzanne Meldrum, Janet A. Dunstan, Jonathon K. Foster, Karen Simmer, Susan L. Prescott

Research outputs 2014 to 2021

A number of trials have been undertaken to assess whether the intake of omega-3 long-chain polyunsaturated fatty acids (n-3 LCPUFA) during pregnancy can influence the neurological development of the offspring, yet no consensus from these trials has been reached. We aimed to investigate the long-term effects (12 years) of fish oil supplementation in pregnancy on neurodevelopment, including cognition, language and fine motor skills. In a follow up of a previously published randomised controlled trial of 98 pregnant women, their children were assessed at 12 years of age using a battery of neurodevelopmental assessments. Fifty participants were assessed at 12 years, …

Strategy For Improvement Of Maternal Health In Nepal, Gehendra Mahara, Xiuhua Gua, Wei Wang

Research outputs 2014 to 2021

Maternal death is a public health problem in like Nepal. Still women have been facing the pregnancy related problems due to inaccessible and poor quality health service as well as a less available health service from skilled health workers. This is due to lack of essential knowledge about pregnancy and its complications. The main aim of this article is to evaluate and synthesize the current public health issues of maternal health of women in Nepal. Syntheses the problems, challenges and issues regarding maternal health and what can be done for the improvement of those problems with the evidence base practice. …

Leadership Skills For Nursing Unit Managers To Decrease Intention To Leave, Michael R. Roche, Christine M. Duffield, Sofia Dimitrelis, Belinda Frew

Research outputs 2014 to 2021

Aim: To examine specific elements of nursing leadership linked to intention to leave, in public acute care hospitals. Background: Nurse turnover is a global issue receiving widespread attention due to prolonged and projected workforce shortages. Nurse management and leadership qualities have been associated with intention to leave and turnover of nurses. The role of the nurse unit managers in the retention of nurses is becoming increasingly important, particularly because of their strong influence on the quality and stability of the work environment. Methods: Data were collected from 6 2 medical, surgical, and mixed units across eleven public acute care hospitals …

Risk Based Optimization For Improving Emergency Medical Systems, Sandhya Saisubramanian, Pradeep Varakantham, Hoong Chuin Lau

Research Collection School Of Computing and Information Systems

In emergency medical systems, arriving at the incident location a few seconds early can save a human life. Thus, this paper is motivated by the need to reduce the response time – time taken to arrive at the incident location after receiving the emergency call – of Emergency Response Vehicles, ERVs (ex: ambulances, fire rescue vehicles) for as many requests as possible. We expect to achieve this primarily by positioning the "right" number of ERVs at the "right" places and at the "right" times. Given the exponentially large action space (with respect to number of ERVs and their placement) and …

Decreasing Blood Culture Contamination In The Ed, Bettina Laier

All Publications

No abstract provided.

Facing Falls By Staying In The Zone, Beatriz Taboada, Charles Juste, Rocio Ramirez

All Publications

No abstract provided.

Outcomes Of Sepsis Patients Using Noninvasive Cardiac Output Monitoring To Guide Fluid Resuscitation, Rosemary Lee, Rosie Sanchez, Laura Berni, Joyce Nealey, Maria Ojeda

All Publications

No abstract provided.

Pediatric Emergency Department Rapid Care Model, Netonua Reyes, Rene Bascoy, Rosa Rousseau, Francisco A. Medina Mejia, Julian Diavanti, Pedro Marin, Tanisha R. Jones, Sandra Young, Andrea Gibson

All Publications

No abstract provided.

Promoting Comfort During Ct-Coronary Angiogram, Margo Archer, Dawn Arevalo, Kelly Vazquez

All Publications

No abstract provided.

A Comparison Of Hip And Knee Torques Produced During A Maximal Effort Full And Partial Back Squat, Jordan Alexander Williams

Dissertations and Theses @ UNI

This study examined the levels of hip and knee torques produced during a one repetition maximum (1RM partial) squat and full squat in order to determine if there would be a difference in the peak torque created at the two depths.

Eight male athletes (standing height = 1.84 ± 0.07 m; mass = 87 ± 14 kg; age 23 ± 2.1 years) volunteered for the study. Each subject performed a 1RM squat at full squat (as low as the participant could go, at least 0° or thigh parallel in relation to the ground) and partial squat (thigh at 45° in …

Collegiate Athletes' Perceptions Of Social Support And Athletic Trainer-Coach Conflict, Nathan Newman

Dissertations and Theses @ UNI

Following an injury, athletes go through a cognitive evaluation to determine if resources are present to manage any potential stress attributed to being injured (e.g., Wiese-Bjornstal et al., 1995). This evaluation determines both behavioral and emotional responses to the injury and can be influenced by a number of factors, including social support (e.g., Wiese-Bjornstal et al., 1998). Social support serves as a resource that allows injured athletes to make a positive cognitive evaluation (e.g., Wiese-Bjornstal et al., 1998). Another factor that could influence the cognitive evaluation is interpersonal conflict. In athletics, interpersonal conflict is present in the form of athletic …

Reliability Of Breathing Rate Assessment And Chest Expansion Measurement: A Pilot Study In Typically Developing Children, Mary-Grace De La Pena, Maryanne Grace Jordan, Edward James Gorgon

Internet Journal of Allied Health Sciences and Practice

Purpose: Despite the apparent acceptance of breathing rate assessment and chest expansion measurement (CEM) among physical therapists, little is known about the measurement properties of these tests and measures especially when administered to children. Reference data from typically developing children have been reported in the literature without investigating the reliability of measurements. This pilot study aimed to systematically explore the feasibility and inter-rater and test-retest reliability of these chest examination methods in children. Method: Nineteen children, 10 males and 9 females, with mean (SD) age of 11.11 (±1.29) years, were selected through convenience sampling. Assessors measured the breathing rate and …

Acl Injuries In Female Athletes: Are Prevention Programs The Answer?, Brooke Chandor

Honors Theses

Around 400,000 people tear their anterior cruciate ligaments (ACLs) every year in the United States. The majority of these injuries occur during athletics, and most commonly to females. Their neuromuscular abilities, anatomies, and hormones put female athletes at a much higher risk of ACL injury than male athletes. The current gold standard of treatment, ACL reconstruction, is an imperfect technique at best. It leaves patients with much higher risk of both ACL reinjury and early onset of osteoarthritis. Prevention programs, aimed at reducing the neuromuscular risk factors in female athletes, have proved to effectively reduce the number of noncontact ACL …

The Growing Crisis In Maine: Neonatal Abstinence Syndrome, Olivia Avidan

Honors Theses

Neonatal Abstinence Syndrome (NAS) is a Maine epidemic. In addition to having medical repercussions, NAS is intrinsically linked to social, political and economic factors. NAS is a conglomeration of symptoms, short-term and long-term, that affect a child that has been exposed to opioids in utero. These factors that impact NAS are interdependent. The past decade is characterized by a dramatic rise in NAS cases in Maine. This paper explores the social, political and economic landscape surrounding NAS in an effort to describe fully the syndrome’s effect on both individuals and the community as a whole.

Multi-Surface Simplex Spine Segmentation For Spine Surgery Simulation And Planning, Rabia Haq

Computational Modeling & Simulation Engineering Theses & Dissertations

This research proposes to develop a knowledge-based multi-surface simplex deformable model for segmentation of healthy as well as pathological lumbar spine data. It aims to provide a more accurate and robust segmentation scheme for identification of intervertebral disc pathologies to assist with spine surgery planning. A robust technique that combines multi-surface and shape statistics-aware variants of the deformable simplex model is presented. Statistical shape variation within the dataset has been captured by application of principal component analysis and incorporated during the segmentation process to refine results. In the case where shape statistics hinder detection of the pathological region, user-assistance is …

Visual Analog Rating Of Mood By People With Aphasia, Tyson G. Harmon, Katarina L. Haley, Jennifer L. Womack, Sharon W. Williams

Faculty Publications

Background:

Considerable attention has been given to the identification of depression in stroke survivors with aphasia, but there is more limited information about other mood states. Visual analog scales are often used to collect subjective information from people with aphasia. However, the validity of these methods for communicating about mood has not been established in people with moderately to severely impaired language.

Objective:

The dual purposes of this study were to characterize the relative endorsement of negative and positive mood states in people with chronic aphasia after stroke and to examine congruent validity for visual analog rating methods for people …

Bidirectional Interference Between Speech And Nonspeech Tasks In Younger, Middle-Aged, And Older Adults, Christopher Dromey, Dallin J. Bailey

Faculty Publications

Purpose: The purpose of this study was to examine divided attention over a large age range by looking at the effects of 3 nonspeech tasks on concurrent speech motor performance. The nonspeech tasks were designed to facilitate measurement of bidirectional interference, allowing examination of their sensitivity to speech activity. A cross-sectional design was selected to explore possible changes in divided-attention effects associated with age. Method: Sixty healthy participants were separated into3 groups of 20: younger (20s), middle-aged (40s), and older (60s) adults. Each participant completed a speech task (sentence repetitions) once in isolation and once concurrently with each of 3 …

Developmental Surveillance And Referral In A Traditionally Medically Underserved Border Community, Eugenia C. Gonzalez, Connie Summers, Vannesa Mueller, Anne Hernandez, Gilda Gil-Lopez, Danielle C. Garcia, Maritza E. Lopez

Faculty Publications

Purpose Early identification and referral have been shown to improve long-term outcomes for children with disabilities. However, the number of children enrolled in early intervention services continues to be lower than the number of children confirmed to be developmentally delayed later in life. This study investigated the pattern of developmental surveillance and referral practices of pediatricians in a traditionally medically underserved border community. Description An online survey was created by members of a community/academic partnership. Emails were followed up with a personal contact to doctor’s offices to increase the response rate. Assessment Response rate for the survey was 26.7 %. …

Examining Legalism, Scrupulosity, Family Perfectionism, And Psychological Adjustment Among Lds Individuals, Kawika Allen, Kenneth T. Wang, Hannah Stokes

Faculty Publications

This study examined the relationships and interactions between legalism, scrupulosity, family perfectionism, guilt, and shame among 421 Latter-Day Saints (LDS or Mormons). The results showed that scrupulosity fully mediated the links between legalism and guilt, as well as legalism and shame. A moderated-mediation effect was found, in which family discrepancy (maladaptive perfectionism) intensified the scrupulosity–shame association in the mediation model of legalism and shame by scrupulosity. Family discrepancy was not a significant moderator for the mediation model of legalism and guilt by scrupulosity. Additional results are provided and implications of these findings are outlined.