Medicine and Health Sciences Commons^™

Use Of Root Cause Analysis In Nursing Education: Best Practice From The Quality And Safety Officer, Elizabeth E. Cooper, Susan Pauly-O’Neill

Nursing and Health Professions Faculty Research and Publications

Teaching nursing students to be safe in practice is a key element to any nursing curriculum. This article will discuss the use of a Root Cause Analysis (RCO) framework with prelicensure nursing students, by the Quality and Safety Officer (QSO) in a School of Nursing and Health Professions, as a method to enhance transparency and improve patient safety. The aim is to provide a rationale for using this strategy, to identify the steps of a root cause analysis, to disclose barriers to its successful use, and to explore dissemination to the partnering healthcare environments.

Internal Attributes That Mitigate Perceived Job Insecurity: Improving Employee Satisfaction, Shelly Leigh Rogers-Sharer

Walden Dissertations and Doctoral Studies

Employee satisfaction has been found to have a strong relationship with perceived job security. This study explored job insecurity in an unstable global economy. Specifically, it examined internal attributes of employees, hypothesizing that such attributes would enable employees to better cope with work-related stressors such as job insecurity. Specific attributes of personality and employability were assessed as potential moderators of job satisfaction and security, utilizing the theory of work adjustment and person-environment correspondence as theoretical frameworks. The specific attributes included facets of conscientiousness and neuroticism as well as dispositions of employability including openness to change at work, work and career …

Designing A Broad-Spectrum Integrative Approach For Cancer Prevention And Treatment, Keith I. Block, Charlotte Gyllenhaal, Leroy Lowe, Amedeo Amedei, A.R.M. Ruhul Amin, Amr Amin, Katia Aquilano, Jack Arbiser, Alexandra Arreola, Alla Arzumanyan, Patricia Hentosh

School of Medical Diagnostics & Translational Sciences Publications

Targeted therapies and the consequent adoption of “personalized” oncology have achieved notable successes in some cancers; however, significant problems remain with this approach. Many targeted therapies are highly toxic, costs are extremely high, and most patients experience relapse after a few disease-free months. Relapses arise from genetic heterogeneity in tumors, which harbor therapy-resistant immortalized cells that have adopted alternate and compensatory pathways (i.e., pathways that are not reliant upon the same mechanisms as those which have been targeted). To address these limitations, an international task force of 180 scientists was assembled to explore the concept of a low-toxicity “broad-spectrum” therapeutic …

Bioactive Lipid Coating Of Bone Allografts Direct Engraftment And Fate Determination Of Bone Marrow-Derived Cells In Rat Gfp Chimeras, Anusuya Das, Claire E. Segar, Yihsuan Chu, Tiffany W. Wang, Yon Lin, Chunxi Yang, Roy C. Ogle

School of Medical Diagnostics & Translational Sciences Publications

Bone grafting procedures are performed to treat wounds incurred during wartime trauma, accidents, and tumor resections. Endogenous mechanisms of repair are often insufficient to ensure integration between host and donor bone and subsequent restoration of function. We investigated the role that bone marrow-derived cells play in bone regeneration and sought to increase their contributions by functionalizing bone allografts with bioactive lipid coatings. Polymer-coated allografts were used to locally deliver the immunomodulatory small molecule FTY720 in tibial defects created in rat bone marrow chimeras containing genetically-labeled bone marrow for monitoring cell origin and fate. Donor bone marrow contributed significantly to both …

Guest Editorial, H S. Ballal Dr

Manipal Journal of Nursing and Health Sciences

No abstract provided.

Use Of An Electronic Educational Module To Educate Advanced Practice Nurses On Preventive Care Protocol For Immunocompromised Patients, Simi Jesto Joseph Dr, Audrey Klopp Dr

Manipal Journal of Nursing and Health Sciences

Immunocompromised patients are at increased risk of infections and certain cancers due to the immunosuppressed body as well as the immunosuppressive agents. Despite American national organizations’ specific guidelines for immunocompromised patients, reported vaccination rates and provider compliance on preventive services is low. The aim of this study was to assess knowledge, attitude and clinical practice among Advanced Practice Nurses (APN) in preventive care for immunocompromised patients and educating APNs to improve their knowledge and practice skills using an evidence-based preventive care protocol. Methods: APN members of Illinois Society of Advanced Practice Nurses (ISAPN) organization were surveyed by a needs assessment …

Clinico Epidemiological Profile Of Hiv-Tb Co-Infected Patients In Coastal South India, Bhaskaran Unnikrishnan Dr, Ramesh Holla Dr, Darshan B. B Dr, Arjun B. Y Dr

Manipal Journal of Nursing and Health Sciences

Introduction: Human Immunodeficiency Virus (HIV) and Tuberculosis (TB) co-infection is considered to be one of the important public health problems globally. Tuberculosis is a leading cause of mortality among people living with HIV/AIDS. Objectives: To find out the trends of HIV and TB co-infection, socio-demographic and clinical profile of HIV and TB co-infected patients. Methods: A hospital based descriptive study was done at a tertiary care teaching hospital in Mangalore. The hospital records of all HIV-TB co-infected patients admitted between January 2008 and December 2013 were reviewed and data were captured in data capture sheet. The data obtained was analysed …

Effectiveness Of Video Assisted Diversional Therapy And Application Of Local Anaesthetic Agent On Pain, Behavioural Response And Physiological Parameters Among Children During Intravenous (Iv) Cannulation, Litna George Ms, Anjalin D'Souza Mrs, Anice George Dr

Manipal Journal of Nursing and Health Sciences

Intravenous (IV) cannulation is a common procedure done in hospitals. Although it is an essential procedure providing easy access for IV hydration or medication, its insertion leads to pain, anxiety and distress in children. The study was undertaken with the objective of comparing the effectiveness of video assisted diversional (VAD) therapy and application of local anaesthetic (LA) agent on pain relief, behavioural response and physiological parameters among children. Methods: The study was done using an experimental post-test only control group design. The participants were randomized to one of the three groups, with 25 subjects in each group: experimental group 1 …

Effectiveness Of Dance Movement Therapy On Attention Deficit Hyperactivity Disorder Children Aged Between 6-12 Years, Shilpa J Ms, Asha P. Shetty Dr

Manipal Journal of Nursing and Health Sciences

Introduction: Attention Deficit Hyperactivity Disorder (ADHD) is one of the most common behaviour disorders of childhood. Mental health and school practitioners are increasingly faced with the challenge of assessing children and adolescents who might have ADHD. The purpose of the study was to assess the effectiveness of dance movement therapy (DMT) among ADHD children. Methods: Data collection was done using demographic proforma; SNAP IV rating scale and an opinionnaire. Results: Analysis revealed post-test teacher and parent mean scores were significantly lower than the pre-test teacher and parent mean scores i.e. the t-value for teacher is t(29)=16.81 and for parent is …

Effectiveness Of A Structured Counselling Program On The Knowledge Of Self-Care Behaviour And Coping Strategies Among Hiv Infected Post-Natal Mothers, Raddi S. A Dr, Prakash R, Dandagi S. R

Manipal Journal of Nursing and Health Sciences

Introduction: Motherhood represents a time of great change that challenges women in many ways. Objectives: The objectives of the study were to evaluate the effectiveness of a structured counselling program in terms of gain in knowledge on Human Immunodeficiency Virus (HIV) and self-care behaviour and increase in use and effectiveness of coping strategies and to find the association between pretest levels of knowledge and coping strategies with selected socio demographic variables. Methods: An evaluative study was carried out to assess the effectiveness of a structured counselling program on knowledge of self care behaviour and coping strategies among HIV infected post-natal …

Effectiveness Of Yoganidra On Quality Of Sleep Among Cancer Patients, Divya N. Anand Ms, Linu Sara George Dr, Anil Raj Mr

Manipal Journal of Nursing and Health Sciences

Introduction: Cancer is one of the major health problems that occur in people of all races and cultures. There is a dearth of literature on implementing non-pharmacological measures to improve quality of sleep among cancer patients. Objectives: This study assessed quality of sleep among cancer patients and the effectiveness of Yoganidra intervention on quality of sleep in terms of improvement using Pittsburgh Sleep Quality Index (PSQI). Methods: A survey was used in Phase I (n=25) to assess the quality of sleep using PSQI. In phase II, an evaluative approach was used through one group pre-test post-test design (n=19).The participants with …

Effectiveness Of Choice Music And Anandabhairavi Raga On Adult Patients’ Pre-Procedural Anxiety, Jomon C. U Mr, Raja A

Manipal Journal of Nursing and Health Sciences

Introduction: Patients become anxious prior to any invasive procedures. In an attempt to relieve anxiety among the patients undergoing invasive endoscopic interventions, music has been proposed as safe and inexpensive antianxiety intervention. Methods: The study aimed to compare the effectiveness of Choice music and Anandabhairavi raga on adult patients’ pre-procedural anxiety in Kasturba Medical College and Hospital (KMCH), Mangalore. Trueexperimental pre-test post-test design was used. Using purposive sampling technique with random assignment, 30 samples each were assigned to both the Choice music and Anandabhairavi raga groups. Pre-procedural anxiety was assessed in both the groups before and after music intervention. Results: …

Stress Factors Among Caregivers Of Children With Thalassemia, Valliammal _. Shanmugam Ms, Ramachandra

Manipal Journal of Nursing and Health Sciences

Introduction: Thalassemia is one of the most common genetic diseases known to mankind. Children with Thalassemia require medical, surgical and nursing care. Family members and caregivers of the affected children play a vital role during treatment. Moreover, they also undergo abundant stress and emotional changes concerning their children’s lives. Objective: To identify factors associated with stress and to correlate the factors with selected demographic variables in caregivers of children with Thalassemia. Materials and Methods: A descriptive survey was conducted among sixty caregivers of children with Thalassemia, admitted in the Thalassemia ward of a selected hospital in Bangalore. Demographic data of …

Statistical And Methodological Challenges In Cochrane Public Health Systematic Reviews: An Overview, Melissa Glenda Lewis Ms, Ravishankar N Mr, Anusha Mujja Ms, Sreekumaran Nair N Dr

Manipal Journal of Nursing and Health Sciences

Background: The article aims to investigate the suitability of Cochrane handbook for the preparation of systematic reviews of public health importance. Methods: The information about various aspects of a systematic review was extracted from all 39 Cochrane public health systematic reviews, independently by three reviewers. This was carried out by means of a data extraction form and was examined if the methodological constructs used by the reviews have been furnished in the Cochrane handbook. Results and Discussion: It was observed that17 (44%) of the 39 reviews adopted meta-analysis and 20(52%) of the systematic reviews used the risk of bias assessment …

Significance Of Herb-Drug Interactions In Clinical Practice: A Narrative Review, K J. Malagi Dr, Kamath Madhusudhana Dr

Manipal Journal of Nursing and Health Sciences

Background: There has been a drastic increase in herb-drug interactions day-by-day as a result of an increase in the population using herb and its supplements along with the contemporary medicines. Objectives: To discuss the safety of usage of herbal medicines along with contemporary medicines in the management of lifestyle disorders. Method: This is a systemic review with narrative analysis. A study was carried out to understand the mode of herb-drug interaction in lifestyle disorders. Literature search was conducted with various titles and reports on medical indexed journals, focusing on herb-drug interaction on selected lifestyle disorders. Conclusion: The issue like herb-drug …

Multiple Fungal Brain Abscesses In A Neonate: Successful Treatment With Liposomal Amphotericin B, Leslie Lewis Dr, Jayashree P Dr, Y Ramesh Bhat Dr

Manipal Journal of Nursing and Health Sciences

Invasive fungal infections are common among infants hospitalized in the Neonatal Intensive Care Unit (NICU). Central Nervous System (CNS) involvement occurs in two third of the disseminated fungal sepsis. Fungal cerebral abscess is one of the severe complications of disseminated fungal sepsis. We report a case of multiple fungal brain abscesses in a term neonate, which was successfully treated with Liposomal Amphotericin B.

Predicting Aqueous Solubility Of Pharmaceutical Agents By Solid Dispersion Prepared By Solvent Evaporation Method, Karthik Reddy Patlolla

University of the Pacific Theses and Dissertations

Solubility of active pharmaceutical agents is a crucial process that determines drug absorption and ultimately its bioavailability. Many of the new therapeutically beneficial compounds discovered are lipophilic requiring various solubility enhancement strategies to improve their solubility. Among these strategies, solubility enhancement using solid dispersions is a leading method. To obtain a desirable increase in the solubility of a poorly-soluble compound, a good understanding of the molecular descriptors influencing the enhancement of solubility is essential. Therefore, the major research objective was to determine the descriptors which significantly influence the solubility enhancement by solid dispersions. After enhancing the solubility of selected poorly-soluble …

The Experience Of Information Literacy In Evidence-Based Practice (Ebp) Among Professional Nurses In The Ho Municipality Of Ghana, Dominic Dankwah Agyei, Christian Yaw Kofi, David Fiankor, Hawa Osman

Library Philosophy and Practice (e-journal)

Purpose: This study aims to find out the information literacy competence of professional nurses in the Ho Municipality of Ghana in their pursuit of Evidence-Based Practice (EBP).

Design/methodology/approach: This study used the descriptive research strategy to describe the experience of information literacy among professional nurses in the Ho Municipality of Ghana. It used the purposive sampling method to select the various health facilities and the professional nurses. A total of 138 questionnaires out of 151 questionnaires that were administered were retrieved. The responses were presented and analysed based on the objectives of the study.

Findings: The study discovered that …

Crash Risk Associated With Cellular Phone Use While Driving, Tiffani Ann Fordyce

Walden Dissertations and Doctoral Studies

There are inconsistencies in the published literature on the effect of cellular phone use while driving. The objective of this study was to estimate an adjusted nationwide crash rate associated with cell phone use while driving and to compare statewide crash rates prior to and following the implementation of legislation banning cell phone use while driving. Crash rates in nationally representative databases were calculated based on imputed values for cell phone use using the propensity score method. The imputed nationwide crash rate for fatal crashes (1.61 per 100 fatal crashes) and all crashes (1.409 per 100 crashes) represented a 2 …

Three Studies On Cardiovascular Health: Modifiable Risk Factors And Health Expenditures In Medicare, Kristal Jo Aaron

All ETDs from UAB

This dissertation comprises a series of studies conducted on modifiable risk factors as they contribute to cardiovascular health and disease and their associated health service expenditures and utilization. Specific topics in this compilation include (1) exploring the role of dietary sodium and potassium intake in cardiovascular health and disease; (2) examination of direct health expenditures in the Medicare-linked REasons for Geographic And Racial Differences in Stroke (REGARDS) cohort as associated with Life’s Simple 7 (LS7), a composite measure of cardiovascular health defined by the American Heart Association (AHA) that is based on seven modifiable risk factors (blood pressure, blood cholesterol, …

The Regulation Of Vitamin A Metabolism, Mark Adams

All ETDs from UAB

Bioactive vitamin A takes form as several molecules, among them all-trans-retinoic acid (RA) is the major form and influences a wide range of biological processes. RA must be synthesized through a two-step mechanism, where all-trans-retinol is first oxidized to all-trans-retinaldehyde by retinol dehydrogenases (RDHs) and retinaldehyde is further oxidized to RA by retinaldehyde dehydrogenases (RALDHs). The first step, retinol to retinaldehyde conversion is the rate limiting step and therefore a likely target of mechanisms that modulate RA synthesis. Despite this, many of the enzymes that are involved in retinol and retinaldehyde interconversion have yet to be identified and thus many …

Competition From New Neurons Drives Circuit Refinement In The Adult Dentate Gyrus, Elena W. Adlaf

All ETDs from UAB

The hippocampus encodes sensory information into memories. The dentate gyrus (DG) region is viewed as the entry point into the hippocampus, receiving sensory and spatial signals from perforant path axons of the entorhinal cortex (EC). Ever since researchers discovered a neurogenic niche in the subgranular zone (SGZ) of the DG in adult animals and humans, many studies have been aimed at discovering how these continually proliferating granule cells (GCs) contribute to the network. Immature GCs have dendrites that project densely into the molecular layer alongside mature GCs and there is morphological evidence that immature excitatory spines preferentially synapse onto existing …

Evaluation Of The Productive Efficiency Of Nurse Practitioners In A Nurse Managed Center In A Highly Restrictive Scope-Of-Practice State, Faraz Ahmed

All ETDs from UAB

The purpose of this study is to determine the productive efficiency of Nurse Practitioners (NP) in a Nurse Managed Center (NMC) in a highly restrictive Scope-of-Practice (SOP) state. NPs are skilled, cost effective and quality health care providers and are considered a highly competitive option for increasing access while reducing health care costs. However, it is not clearly known if NPs are the most productively efficient at delivering this reduced cost of health care. The theories of Complex Adaptive Systems (CAS) and Resource Based View (RBV) were used as a framework to develop the hypotheses that examined the productive efficiency …

Pathophysiology And Metabolic Dysfunction Following Polytrauma, Robert Mackay Akscyn

All ETDs from UAB

Polytrauma, a combination of injuries to more than one body part or organ system, is common in modern warfare and in automobile and industrial accidents. The combination of injuries can include burn, fracture, hemorrhage, trauma to the extremities, and trauma to specific organ systems. These injuries are highly survivable when occurring singly. However, when they occur in combination the prognosis is worsened. To investigate the effects of combined injuries, we have developed a new and highly reproducible model of polytrauma. This model combines burn injury with soft tissue and gastrointestinal (GI) tract trauma. Male Sprague Dawley rats were subjected to …

Association Between Physical Activity And Learning, Pain Coping Strategies, Perceived Stress, And Depression Among Adults With Diabetes And Chronic Pain, Susan J. Andreae

All ETDs from UAB

In addition to the role of physical activity (PA) in the prevention of chronic disease and premature death, PA may have psychosocial benefits. We examined the association between four different domains of PA and three outcomes that may contribute to the emotional and mental well being of individuals. This is a secondary analysis of community dwelling adults with diabetes and chronic pain in which we examined the association between four domains of PA and learning (measured using diabetes knowledge, self efficacy in diabetes and pain management), pain coping strategies, perceived stress, and depression. Regression models were used to model changes …

The Emotions, Coping And Social Support Perceived By Ncaa Division I Athletes During Concussion Recovery: A Qualitative Study, Paige Wells

College of Graduate Studies: Theses & Dissertations

Context: Concussed patients require an individualized assessment and treatment plan in order to improve the outcomes associated with their overall recovery. A new model has been created to explain the psychological response to sport concussion injury and rehabilitation process. This model highlights pre-injury and post-injury factors affecting the recovery process including emotions, coping and social support. Understanding the emotional disturbances, coping behaviors and social support available to concussed athletes may provide valuable information for the healthcare team in management and care for the concussed athlete.

Purpose: To identify and describe the emotions, coping mechanisms and social support perceived by Division …

Examination Of Racial/Ethnic Disparities In Ovarian Cancer Stage Of Diagnosis, Surgery Treatment And Survival: Multilevel Analysis Of 2001-2012 Seer Data, Chen Chen

College of Graduate Studies: Theses & Dissertations

Context. Racial/ethnic disparities in cancer outcomes are major public health concerns. Ovarian cancer is the tenth most common cancer and the fifth leading cause of cancer-related deaths among women. Identifying individual- and contextual-level factors contributing to racial/ethnic disparities in ovarian cancer stage of diagnosis, surgery treatment and survival is necessary for reducing and eliminating these disparities.

Objective. The study aims to examine racial/ethnic disparities in ovarian cancer diagnosis, surgery treatment and survival outcomes; to explore individual- and contextual-level factors contributing to these disparities, and to examine the trend of ovarian cancer racial/ethnic disparities from 2001 to 2012.

Methods. The …

The Effects Of Subconcussive Impacts On Postural Stability, Eric Shiflett

College of Graduate Studies: Theses & Dissertations

Context: The effects of concussions on postural stability, both acutely and chronically, have been well studied and noted. However, whether subconcussive impacts lead to these same impairments is not heavily investigated. Objectives: The primary purpose of this study was to examine the effects of subconcussive impacts on postural stability in NCAA Division I football athletes. We hypothesized that all participants would show declines in postural stability following a single fall season. We also hypothesized that there would be no significant differences between groups from pre- to post-season measures. The secondary purpose was to predict deficits in postural stability based on …

Utilization Of B-Mode Ultrasound As A Body Fat Estimate In Collegiate Football Players, Parker Hyde

College of Graduate Studies: Theses & Dissertations

The purpose of the present study was to validate a 7-site ultrasound imaging protocol to predict percent body fat (%BF) in a Division I football team. Body composition was estimated by ultrasound, seven site skinfolds (SKINFOLD), and the three compartment-water (3C-W) model of Siri (1961), using Bioimpedance spectroscopy (BIS) to estimate total body water (TBW) and air-displacement plethysmography (BODPOD^®) to determine body density (Db). Pearson’s product-moment correlation analyses were run to determine between Σ_Ultrasound and the criterion 3C-W, and between the Σ_Skinfold and Σ_Ultrasound. Strong positive correlations were observed between Σ_Skinfold and Σ …

Development And Characterization Of A Live-Attenuated Vaccine To Combat Equine Herpesvirus Type-1 Infections, Shiliang Anthony Liu

LSU Doctoral Dissertations

Equine Herpesvirus 1 (EHV-1) is an important ubiquitous enzootic equine pathogen and one of the most common pathogens of the horse, causing, respiratory disease, epidemic abortion, occasionally neurological disease in horses, which leads to significant economic losses to the horse industry. EHV-1 induces several clinical signs of disease ranging in severity, from mild respiratory disease to abortion in pregnant mares, neonatal foal death and neuropathogenic disorders. Natural EHV-1 infection stimulated short lived protective immunity and had both humoral and cellular immune responses. Currently vaccination remains the best option to prevent EHV-1 infection and different applications of vaccination have been investigated …