Medicine and Health Sciences Commons^™

The Relationship Among Math Anxiety, Mathematical Performance, And Math Education In Undergraduate Nursing Students, Joshua D. Beall, Troy Roebuck, Paul Penkalsky

Williams Honors College, Honors Research Projects

Although nurses spend up to 40% of their day calculating and administering medication doses, undergraduate nursing students often perform poorly on nursing math exams. The purpose of this study was (a) to examine the relationship among mathematical education, performance, and anxiety and (b) to compare the mathematical education, performance, and anxiety in sophomore and senior baccalaureate nursing students at a public university in the Midwest. This cross-sectional, descriptive study was guided by Bandura's self-efficacy theory. Math performance was measured with an 11-item math instrument, math education was measured with number of math courses, and math anxiety was measured with Fennema–Sherman …

Wellness Wednesday: Monitoring Lifestyle Changes Via The Transtheoretical Model, Mariah J. Bloom Ms.

Williams Honors College, Honors Research Projects

Physical activity has been shown to improve cognition, functional and overall health indicators across the lifespan. Older adults are less likely to participate in physical due to barriers and risk related factors. Additionally, lower income, underserved populations experience added barriers as well. Interventions addressing negative health behaviors in these populations have rarely been implemented. PURPOSE: Using the Transtheoretical Model (TTM) behavior change theory, the purpose of this study was to determine if five, monthly educational and exercise classes targeting these populations will improve motivation levels and result in facilitating increases in physical activity levels. METHODS: One validated TTM survey was …

Women's Fitness Week, Claire T. Lucas, Tiffany M. Finch

Williams Honors College, Honors Research Projects

This project addressed women’s wellness. Many women experience physical and mental health issues related to a lack of physical activity or psychological support. Women’s Fitness Week was offered to women of the University of Akron and the outside community, providing opportunities to learn more about and improve upon the various dimensions of wellness – emotional, environmental, financial, intellectual, occupational, physical, social/cultural, and spiritual. Events were held at the University’s Student Recreation and Wellness Center and encompassed topics such as nutrition, weight training, and self-defense. The goals of this project were to: increase knowledge levels of fitness, health, and wellness, increase …

Shotblocker® - Bionix® Senior Design, Samuel Dockery

Williams Honors College, Honors Research Projects

No abstract provided.

The Effects Of Vitamin D Supplementation On Influenza, Jonah M. Spoerndle

Williams Honors College, Honors Research Projects

Recently the role of vitamin D in other non-classical capacities has been evaluated. One of these non-classical vitamin D roles is assisting in maintaining proper immune system health. One disease that has a great effect on the immune system is influenza. Vitamin D helps to prevent and limit influenza by moderating the inflammatory cytokines as well as promoting the production of monocytes that help destroy the invading materials. Through the use of vitamin D supplementation the recommended daily amount of vitamin D can be assured and optimal health could be achieved. The purpose of this project was to design a …

A Systematic Review: Immediate And Maintenance Effects Of Interventions On Handwashing Compliance In Healthcare Workers, Brent E. Gibson, Dajana Markovic

Williams Honors College, Honors Research Projects

There has been a drastic rise in the number of nosocomial infections of patients in intensive care units. Handwashing is generally accepted as an effective and inexpensive method that healthcare providers in hospital settings can use to decrease the likelihood of nosocomial infections, however, studies have shown that healthcare providers are often not compliant with handwashing protocol. The purpose of this systematic review of literature is to not only obtain information on handwashing compliance and non-compliance among different healthcare providers, but also to identify, describe, and evaluate evidence about the effect of various interventions on handwashing compliance in healthcare providers. …

Kangaroo Care And Preterm Infants, Natalie Schindler, Kathryn Lynn

Williams Honors College, Honors Research Projects

Infants that are born near-term or before they reach their full gestational age of 40 weeks are at risk for facing future health problems and disparities in terms of proper development (Ladewig, London, & Davidson, 2012). This has been a major concern in the medical realm because of the high cost of managing preterm newborns and the complications that can develop. However, kangaroo care may aid in physical growth and cognitive development of these infants. The purpose of this integrative review was to determine if current research shows that kangaroo care has a positive effect on preterm infants in the …

Review Of The Accuracy Of Two Pain Assessment Tools In Nonverbal Adult Patients, Mackenzie Mosley, Emily Hartman, Kristen Tankovich, James Galantis

Williams Honors College, Honors Research Projects

Intensive care units frequently have patients that are unable to verbally communicate their pain, thus negating conventional pain assessment techniques and making pain assessment difficult. Pain management is often a priority in all patients’ circumstances and therefore, assessment and reassessment are included in the plan of care. Different observational pain scales have been used in intensive care units, but often times these scales must be adapted to fit the patient’s circumstances. Pain scales that are used for nonverbal patients typically include behavioral indicators and some are adapted to incorporate physiologic indicators such as vital signs. The aim of this review …

Caregiver Perceptions Of Healthcare Providers And Environments Related To Children With Autism Spectrum Disorder, Deanna Klettlinger, Lynn Wirfel, Brittany Bielak

Williams Honors College, Honors Research Projects

The healthcare setting can be intimidating for any child. For children with autism spectrum disorder (ASD), in particular, this setting can cause anxiety and elicit disruptive behavior. The reactions of children with ASD to healthcare settings have not been widely studied. This study explores the lived experience of caregivers of children with ASD related to healthcare providers and environments. A qualitative phenomenological approach and methods guide the study. Purposive sampling was utilized at a resource center to identify and recruit participants fulfilling inclusion criteria. Sample size consisted of four female and two male adults. Semi-structured interviews were performed and voice …

Multi-Modal Communication In School-Age Children With Autism Spectrum Disorders, Lauren Dougherty

Williams Honors College, Honors Research Projects

Children with Autism Spectrum Disorder (ASD) have a difficult time communicating on a daily basis. To help enhance and sometimes substitute speech altogether, they require Augmentative and Alternative Communication (AAC) devices. A review of literature found that school-age children with ASD utilize multiple modes of communication. The observation conducted looked at six school-age children, grades 6-8, with ASD and their use of multimodal communication. Each child was observed throughout their school day in settings such as the classroom, lunch/recess, and the speech therapy room. Data was collected for the number of times a child was given the opportunity to use …

The Effect Of An Educational Hunger Cues Intervention On Awareness In Mothers With Infants, Juliana F. Gill, Ellen A. Vierheller

Williams Honors College, Honors Research Projects

Stress to an infant can inhibit the ability to properly feed and gain the nutrients that are essential for efficient growth. Mothers who are unaware of early hunger cues from their infant have the potential to stress the infant if their early hunger cues are not attended to. The purpose of this study was to examine the effect of an educational hunger cues intervention on awareness in mothers with an infant. The following research question will be answered: Will new mothers who complete an educational intervention show increased awareness of hunger cues in their infants, in comparison to before the …

A Survey Of Speech-Language Pathologists On Facilitating Support Groups For Those With Communication Disorders, Danielle A. Hower, K. Todd Houston Ph.D

Williams Honors College, Honors Research Projects

Support groups are used in a variety of settings and can be helpful for group members to develop coping strategies. This research aims to evaluate Ohio Speech-Language Pathologists’ perceived knowledge of planning and implementing support groups. Another goal for this research is to gain information on how many Speech-Language Pathologists are using this knowledge to conduct a support group, what type of populations are benefiting, and in what setting type utilizes support groups.

A Comparison Of Empathy In Sophomore And Senior Baccalaureate Nursing Students, Alexandra I. Woods, Stephanie Malachin

Williams Honors College, Honors Research Projects

Empathy is a cognitive process rather than an emotional and is often learned through life. Hildegard Peplau’s theory of interpersonal relations explains the importance of the nurse having a shared experience with the patient. Empathy is a crucial skill for nursing students to develop because it is shown that nurses showing empathy is directly related to improved patient satisfaction. Empathy levels tend to decrease as students progress throughout nursing school. The purpose of this study is to examine the empathy levels in sophomore baccalaureate nursing students compared to senior baccalaureate nursing students. Using a descriptive comparison design and a cross-sectional …

Reversible Linkage Of Two Distinct Small Molecule Inhibitors Of Myc Generates A Dimeric Inhibitor With Improved Potency That Is Active In Myc Over-Expressing Cancer Cell Lines, Jutta Wanner, Darlene Romashko, Douglas S. Werner, Earl W. May, Yue Peng, Ryan Schulz, Kenneth W. Foreman, Suzanne Russo, Lee D. Arnold, Maneesh R. Pingle, Donald E. Bergstrom, Francis Barany, Stuart Thomson

Borch Department of Medicinal Chemistry and Molecular Pharmacology Faculty Publications

We describe the successful application of a novel approach for generating dimeric Myc inhibitors by modifying and reversibly linking two previously described small molecules.We synthesized two directed libraries of monomers, each comprised of a ligand, a connector, and a bioorthogonal linker element, to identify the optimal dimer configuration required to inhibit Myc. We identified combinations of monomers, termed self-assembling dimeric inhibitors, which displayed synergistic inhibition of Myc-dependent cell growth. We confirmed that these dimeric inhibitors directly bind to Myc blocking its interaction with Max and affect transcription of MYC dependent genes. Control combinations that are unable to form a dimer …

Assertiveness In Nursing Students, Kaitlin F. Amicone, Rachel Miller

Williams Honors College, Honors Research Projects

The problem that this study focused on was that there was minimal evidence on whether or not nursing students become more assertive throughout their academic education. The purpose of this study was to compare the assertiveness scores of sophomore level nursing students and senior level-nursing students. The study was guided by Hildegard Peplau’s theory of interpersonal relations in nursing, which focuses on the therapeutic process between nurses and patients, rather than on internal patient pathology. The descriptive, comparative study used a 15-question survey design and a convenience sample of sophomore and senior level nursing students at a large urban Midwest …

The Effects Of Sustainability As A Positive Attribute On Equine Therapy Design: An Interdisciplinary Study, Andria Sinclair

Williams Honors College, Honors Research Projects

Interdisciplinary studies have brought benefits to introducing new solutions to the traditional environment and traditional therapies. Sustainability in relation to design has been suggested in 2006, by the Center for Building Performance and Diagnostic (CBPD) at Carnegie Mellon University to incorporate daylight, solar, heat and ventilation of the natural environment combined with the innovations of current technologies (Whitmore, 2011). This paper will look at how sustainability plays a key role of benefits including those that are health associated with equine therapy design and its relationship to the patient, or end user. Interdisciplinary research in the therapeutic value of equine-human bonding …

Tactical Medicine: An Examination Of Medical Training In Law Enforcement, Brian J. Woods Jr.

Williams Honors College, Honors Research Projects

In recent years, there has been a trend towards making law enforcement officers more well-rounded first responders by increasing their required medical competencies. The required medical competencies of six law enforcement agencies of varying sizes in Northeast Ohio were examined by interviews conducted with a representative from each agency. Interview question topics included information on current training requirements and the types of medical equipment issued to officers. The study found that all six of the agencies surveyed offered medical training to officers as part of required continuing education, and all six agencies currently issued, or planned to issue in the …

Transdermal Iontophoretic Delivery Of Lipophilic Drugs, Abhishek Juluri

Electronic Theses and Dissertations

Iontophoresis is one of the most widely studied active technique for enhancing transdermal delivery of drugs. However, its ability to enhance the delivery of highly lipophilic compounds is poor due to lack of any charge and poor water solubility of molecules. Propofol, a sedative and anesthetic drug was chosen as a one of the model lipophilic drug in this study. Initially, feasibility of delivery of propofol phosphate, a water soluble prodrug of propofol, via transdermal route using iontophoresis in combination with chemical permeation enhancers was investigated. Cathodal iontophoresis in combination with 0.1% sodium dodecyl sulphate synergistically enhanced the flux of …

Lipid & Surfactant Based Systems For Improved Delivery Of Poorly Soluble Apis, Sri Satyasai Nagendra Babu Punyamurthula

Electronic Theses and Dissertations

A large number of pharmaceutical compounds belong to class II and IV of biopharmaceutical classification of drug (BCS). Class II compounds are limited by their poor aqueous solubility, while class IV compounds suffer from poor solubility and permeability. This translates to poor absorption and low plasma levels post oral administration. Lipids comprise of fatty acids and their derivatives and are considered a biocompatible option for drug delivery. In the studies discussed in following chapters, lipid based drug delivery systems (LBDDS) have been utilized in improving the handling, ease of formulation, solubility and bioavailability of three compounds. In the first study, …

Protein-Ligand Interaction Studies And Identification Of New Drug-Like Hits As Cannabinoid Receptor Modulators, Pankaj Pandey

Electronic Theses and Dissertations

The cannabinoid receptors (CB1 and CB2) belong to the family of class A GPCRs. The CB1 receptor is predominately found in the central nervous system and regulates various neuromodulatory and physiological processes while CB2 receptors are found in peripheral tissues, particularly in the immune system tissues. This dissertation reports several projects including: (1) an examination of the putative binding modes of Cannabis-derived ligands with CB1 and CB2 receptors, (2) the identification of novel CB1 inverse agonists, and (3) the identification of allosteric site(s) in the CB2 receptor and screening of new CB2 allosteric modulators (AMs).

Chapter 1 describes background information …

Versatility Of Hot-Melt Extrusion For Dosage Form Design, Sultan Mohammad Alshehri

Electronic Theses and Dissertations

Recently, Hot Melt Extrusion (HME) has attracted the attention of pharmaceutical companies and scientists as a technique for manufacturing a variety of dosage forms. In this research, HME was applied in different ways to achieve different goals, such as solubility enhancement, taste masking, solid state stability enhancement, and sustained release formulations for oral drug delivery, using one model drug, mefenamic acid. For solubility enhancement and taste masking formulations, Eudragit EPO was blended with MA in different ratios (20, 25, 30, and 40% of drug loads) and processed by a hot melt extruder to produce a solid dispersion system. FT-IR analysis …

Quality Of Life And Healthcare Utilization And Costs Among Adults With Autism, Krutika Maulik Jariwala-Parikh

Electronic Theses and Dissertations

OBJECTIVES The objectives of this study are to: 1) assess construct validity of the World Health Organization’s Quality of Life-BREF (WHOQOL-BREF) instrument, 2) evaluate quality of life (QOL) among adults with autism and 3) assess the prevalence, healthcare utilization and costs, and medication use among adults with autism enrolled in the Medicaid program. METHODS The study methodology included both primary and secondary data collection techniques. For objectives one and two, a cross-sectional, descriptive quantitative design was utilized. An internet-based survey using Qualtrics was administered to adults with autism enrolled with the Interactive Autism Network (IAN). The WHOQOL-BREF instrument was validated …

Polymer Interactions With Nucleic Acids Under Various Physiological Conditions, Matthew S. Obrzut

Williams Honors College, Honors Research Projects

The goal of this project is to improve our understanding of nucleic acid interactions with cationic polymers with the theory that the polymers could protect the nucleic acids from degradation caused by biological enzymes. We seek to understand what the limitations of the cationic polymers are which, in this case, is mainly polymer-DNA compatibility. This experiment utilized peptide-dextran hybrid polymers with differing functionalizations to condense anionic nucleic acids into nanometer-sized polyplexes. Techniques of dynamic light scattering and zeta-potential were utilized to determine the particle sizes and surface charges of polyplexes.

In this experiment, dextran with a molecular weight of 20 …

The Effects Of Instructional Strategies On Adherence To A Flexibility Program And Physiological Outcomes, Taylor M. Graham

Williams Honors College, Honors Research Projects

Health care professionals construct exercise prescriptions for clients and patients to complete on their own. Exercise specialists, physical therapists, occupational therapists, and exercise physiologists are all considered health care professionals for this study. Furthermore, the importance of flexibility and stretching is commonly overlooked. The purpose of this research study was to compare whether or not different instructional techniques affect adherence to a stretching routine, and if followed were improvements gained in quadriceps and hamstring flexibility. Thirty-one students from The University of Akron between the ages of 18 and 37 with an average height of 66.7 inches and average weight of …

Relationship Between Stages Of Change And Hpv Vaccine Attitudes And Beliefs In Baccalaureate Nursing Students, Megan M. Stein, Michael Sabo, Julia Caverly

Williams Honors College, Honors Research Projects

The purpose of this study was to: (a) determine if there is a relationship between attitudes/beliefs about Human papillomavirus (HPV) vaccination and stages of change and (b) investigate gender differences in attitudes/beliefs and stages of change in undergraduate baccalaureate nursing students. The study employs a cross-sectional and descriptive correlational design and it was guided by the Trans-theoretical Model of Change (TMC). The convenience sample was comprised of 131 participants at a large urban public university in Midwest United States. Data were collected with online surveys distributed via university email. A positive, moderate relationship was found between HPV vaccination attitudes/beliefs and …

A Systematic Review: Non-Pharmacological Interventions For Chemotherapy-Induced Nausea And Vomiting, Miranda L. Ayers, Olateju F. Olowe

Williams Honors College, Honors Research Projects

Around 70-80% of patients receiving chemotherapy are at risk of chemotherapy-induced nausea and vomiting (CINV), which can interfere with appetite and the ability to perform normal activities for daily living. When CINV is severe, psychological distress, depression, and physiological impairment occur. Patients may also stop chemotherapy treatments, which can lead to untimely deaths. The aim of this systematic review was to identify, describe, and evaluate the evidence about the use and effectiveness of non-pharmacological interventions, compared to no use of non-pharmacological interventions, on self-reported episodes of CINV among the cancer patients. Twenty articles were reviewed on the use of acupressure, …

Induced And Spontaneous Labor Education: Evaluation, Knowledge, And Intent To Discuss Options In Pregnant Women, Kathleen Hartzell, Katherine Bartolotta

Williams Honors College, Honors Research Projects

Labor inductions are increasing worldwide, with rates continuing to rise each year. Currently 30% of labors in the United States result from inductions. The purpose of the study was to examine the effect of an educational intervention about induced and spontaneous labor on knowledge and intent to discuss options with health providers in pregnant women. This study was guided by the health-belief model which explains that people’s beliefs about how a health care decision may affect their lives affect how they make the decisions. This study was conducted using a quantitative and descriptive design with pre and post paper and …

Differences In Health Literacy Knowledge And Experiences Among Senior Nursing Students, Sharon S. Williamson, Joanne Chopak-Foss

Community Health: Faculty Publications

Background: Low health literacy has been identified as a significant public health problem. Also, higher expenditures due to longer hospital stays have been reported for persons with low health literacy. Nurses can assist patients with low health literacy to reduce their hospital stays and increase compliance with discharge instructions.

Methods: A quantitative, descriptive research design was employed to assess knowledge and experiences of 192 senior nursing students. These students were administered the Health Literacy Knowledge and Experiences Survey (HL-KES), a 2- part survey that included assessment of knowledge about health literacy and experience in working with populations of …

Unstable Ventilatory Control During Sleep After High Spinal Cord Injury: The Contribution Of Chemosensitivity And Hypoventilation, Amy Therese Bascom

Wayne State University Dissertations

ABSTRACT

UNSTABLE VENTILATORY CONTROL DURING SLEEP AFTER HIGH SPINAL CORD INJURY: THE CONTRIBUTION OF CHEMOSENSITIVITY AND HYPOVENTILATION

by

Amy T. Bascom

May 2015

Advisor: Dr. Harry G. Goshgarian

Major: Anatomy and Cell Biology

Degree: Doctor of Philosophy

A high prevalence of sleep-disordered breathing (SDB) after spinal cord injury (SCI) has been reported in the literature; however, the underlying mechanisms are not well understood. My studies had 2 aims: 1) to determine the effect of the withdrawal of the wakefulness drive to breathe on the degree of hypoventilation in SCI patients and able-bodied controls and 2) to determine the response of …

Evaluating The Relationship Between Diadochokinesis And Severity Of Dysphagia As It Relates To Forced Vital Capacity In Individuals With Amyotrophic Lateral Sclerosis, Arthur Franklin Knack

Wayne State University Dissertations

Purpose: To determine if the severity of dysphagia, as determine by Penetration Aspiration Scale (PAS) ratings and pharyngeal residue scale ratings in individuals with ALS, can be predicted through performance on diadochokinesis (DDK) and force vital capacity (FVC) measures.

This study was designed to evaluate differences in performance of clinical measures and objective swallowing severity ratings between individuals with ALS and a Control group of similar age. The goal of this study was to attempt to develop a clinical assessment battery that can predict swallowing impairment in ALS patients. In addition, potential predictive relationships between dysphagia ratings and other commonly …