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2014

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Articles 91 - 120 of 9579

Full-Text Articles in Medicine and Health Sciences

Secondary Mental Health Conditions Of Rural Adults With Disabilities, Craig Ravesloot Ph.D., Bob Liston, Kevin Thorsen, Charles Asp, University Of Montana Rural Institute Dec 2014

Secondary Mental Health Conditions Of Rural Adults With Disabilities, Craig Ravesloot Ph.D., Bob Liston, Kevin Thorsen, Charles Asp, University Of Montana Rural Institute

Health and Wellness

No abstract provided.


Psychiatric Symptoms Reported By A Population-Based Sample Of Rural Adults With Physical And Sensory Impairments, Craig Ravesloot Ph.D., Charles Asp, Bob Liston, Kevin Thorsen, University Of Montana Rural Institute Dec 2014

Psychiatric Symptoms Reported By A Population-Based Sample Of Rural Adults With Physical And Sensory Impairments, Craig Ravesloot Ph.D., Charles Asp, Bob Liston, Kevin Thorsen, University Of Montana Rural Institute

Health and Wellness

No abstract provided.


Cost Containment Through Disability Prevention: Preliminary Results Of A Health Promotion Workshop For People With Physical Disabilities, Tom Seekins Ph.D., Craig Ravesloot Ph.D., Kay Norris Ph.D., Ann Szalda-Petree Ph.D., Quincy-Robyn Young, Glen White Ph.D., Ken Golden M.A., Juan Carlos Lopez M.A., Julie Steward, University Of Montana Rural Institute Dec 2014

Cost Containment Through Disability Prevention: Preliminary Results Of A Health Promotion Workshop For People With Physical Disabilities, Tom Seekins Ph.D., Craig Ravesloot Ph.D., Kay Norris Ph.D., Ann Szalda-Petree Ph.D., Quincy-Robyn Young, Glen White Ph.D., Ken Golden M.A., Juan Carlos Lopez M.A., Julie Steward, University Of Montana Rural Institute

Health and Wellness

The Disability Prevention Project at the University of Montana and the University of Kansas has developed and evaluated an eight week workshop and self-help manual that targets the prevention and management of secondary conditions among adults with spinal cord injuries. The preliminary results of this intervention are very encouraging.


Unilateral Heat Accelerates Bone Elongation And Lengthens Extremities Of Growing Mice, Maria A. Serrat, Thomas J. Schlierf, Morgan L. Efaw, Franklin D. Shuler, Justin Godby, Laura M. Stanko Dec 2014

Unilateral Heat Accelerates Bone Elongation And Lengthens Extremities Of Growing Mice, Maria A. Serrat, Thomas J. Schlierf, Morgan L. Efaw, Franklin D. Shuler, Justin Godby, Laura M. Stanko

Orthopaedics

Linear growth failure results from a broad spectrum of systemic and local disorders that can generate chronic musculoskeletal disability. Current bone lengthening protocols involve invasive surgeries or drug regimens, which are only partially effective. Exposure to warm ambient temperature during growth increases limb length, suggesting that targeted heat could noninvasively enhance bone elongation. We tested the hypothesis that daily heat exposure on one side of the body unilaterally increases femoral and tibial lengths. Mice (N = 20) were treated with 40 °C unilateral heat for 40 min/day for 14 days post-weaning. Non-treated mice (N = 6) served as controls. Unilateral …


Pulmonary Arteriovascular Malformation: A Rare Cause Of Unexplained Hypoxia And Acute Dyspnoea In Young Patients, Nousheen Iqbal, Karim Abdur Rehman, Javaid Ahmed Khan, Tanveer Ul Haq Dec 2014

Pulmonary Arteriovascular Malformation: A Rare Cause Of Unexplained Hypoxia And Acute Dyspnoea In Young Patients, Nousheen Iqbal, Karim Abdur Rehman, Javaid Ahmed Khan, Tanveer Ul Haq

Section of Pulmonary & Critical Care

2014 BMJ Publishing Group Ltd.Pulmonary arteriovenous malformations (PAVMs) are anomalous vascular connections between arteries and veins in the lung and comprise of two types, simple and complex. PAVMs are associated with congenital conditions such as hereditary haemorrhagic telengiectasia along with acquired causes. We present a case of a 26-year-old man who presented with dyspnoea, palpitations and decreased oxygen saturation as an initial presentation of PAVM, which was treated successively with embolisation.


Conditions Préalables À L’Implantation De La Rotation Chez Une Population D’Assembleurs-Monteurs Du Secteur De L’Aéronautique : L’Impact Des Exigences De Qualité Sur Le Développement De La Polyvalence Et Sur L’Apprentissage, Denys Denis, Marie St-Vincent, Maud Gonella Dec 2014

Conditions Préalables À L’Implantation De La Rotation Chez Une Population D’Assembleurs-Monteurs Du Secteur De L’Aéronautique : L’Impact Des Exigences De Qualité Sur Le Développement De La Polyvalence Et Sur L’Apprentissage, Denys Denis, Marie St-Vincent, Maud Gonella

Rapports de recherche scientifique

Une grande entreprise du secteur de l’aéronautique désire développer la polyvalence de ses assembleurs-monteurs par l’instauration de la rotation de postes. Convenant qu’il s’agit d’une problématique complexe, l’expertise de l’Institut de recherche Robert-Sauvé en santé et en sécurité du travail (IRSST) est sollicitée. La demande formulée consiste à identifier les conditions requises pour implanter la rotation des postes, souhaitant ainsi prévenir les TMS qui affectent cette population de travailleurs. Le département où sont assemblés les cabines de pilotage de deux des avions-phares de l’entreprise est ciblé à la fois de par les exigences physiques qui le caractérisent, sa …


Research Brief: "The Potential For Health-Related Uses Of Mobile Phones And Internet With Homeless Veterans: Results From A Multisite Survey", Institute For Veterans And Military Families At Syracuse University Dec 2014

Research Brief: "The Potential For Health-Related Uses Of Mobile Phones And Internet With Homeless Veterans: Results From A Multisite Survey", Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

This brief is about the use of mobile phones among homeless veterans for medical appointment reminders, and other health services provided by healthcare practitioners. In policy and practice, social workers and counselors should determine whether mobile communication would benefit homeless veterans with whom they work and should identify certain barriers to mobile communication that could exist; the VA should expand its mobile notification efforts and look for programs that reduce barriers to regular access to mobile communication. Suggestions for future research include expanding the sample of homeless veterans to include those who are living on the streets or in a …


Consumer Assessment Of Healthcare Providers And Systems (Cahps) Surveys: Assessing Patient Experience, Lisa Sprague Dec 2014

Consumer Assessment Of Healthcare Providers And Systems (Cahps) Surveys: Assessing Patient Experience, Lisa Sprague

National Health Policy Forum

This publication provides an overview of the Consumer Assessment of Healthcare Providers and Systems (CAHPS) family of surveys, which are widely used by both public and private health plans and providers to assess the patient's experience of health care. Included is information on survey contents, how surveys are tailored to different users, and how the resulting information is collected, reported, and used to help consumers make choices and providers carry out quality improvement, as well as its role in pay-for-performance reimbursement.


Bovine Colostrum Supplementation Optimises Earnings, Performance And Recovery In Racing Thoroughbreds, C. K. Fenger, Thomas Tobin, P. J. Casey, Edward A. Roualdes, J. L. Langemeier, D. M. Haines Dec 2014

Bovine Colostrum Supplementation Optimises Earnings, Performance And Recovery In Racing Thoroughbreds, C. K. Fenger, Thomas Tobin, P. J. Casey, Edward A. Roualdes, J. L. Langemeier, D. M. Haines

Maxwell H. Gluck Equine Research Center Faculty Publications

Bovine colostrum (BC) is the first milk produced by cows after calving and contains numerous beneficial substances for the immunity and development of the newborn calf. Because of the growth and immune factors in BC, it has become an attractive supplement for use by athletes to support immunity and health during athletic performance. In order to evaluate the effects of oral BC supplementation on equine athletes, this study evaluated the earnings, performance, recovery and incidence of upper respiratory infections (URTI) in racing horses. The study design was a randomized cross-over racing performance study. 21 horses in race training were randomly …


The Narratives Of Young Women With Brca 1/2 Gene Mutation: A Qualitative Analysis, Drew D. Reilly Dec 2014

The Narratives Of Young Women With Brca 1/2 Gene Mutation: A Qualitative Analysis, Drew D. Reilly

LSU New Orleans Theses and Dissertations

A narrative qualitative research design was used to understand the stories of young women diagnosed with BRCA1 and BRCA 2 genetic mutation. Four participants were selected who met the following criteria: (a) the participant is diagnosed with BRCA1 or BRCA2 genetic mutation, b) is within the age range of 18 to 35, (c) is without a cancer diagnosis, and is (d) not currently pregnant and does not have children. The four participants were interviewed through open-ended inquiry. The participants’ narratives proved both similar and dissimilar. The themes were organized into within-case narratives and across-case narratives. The narratives revealed that young …


Residency Education In Preparing Adolescent And Young Adults For Transition To Adult Care: A Mixed Methods Pilot Study, Janet S. Hess Dec 2014

Residency Education In Preparing Adolescent And Young Adults For Transition To Adult Care: A Mixed Methods Pilot Study, Janet S. Hess

USF Tampa Graduate Theses and Dissertations

Background: There is considerable evidence that physicians lack sufficient training in facilitating transition from pediatric to adult care systems for adolescents and young adults (A/YA). While several primary care residency programs have introduced health care transition (HCT) curricula in recent years, there are few studies that assess the effectiveness of HCT teaching models.

Purpose: To assess the impact of a residency education program that uses electronic health records (EHR) and other methods to teach residents how to prepare A/YA for transition to adult care.

Methods: In a mixed methods, quasi-experimental research design, quantitative methods were used to measure change in …


Stigmatized And Getting High, Emma M. Murphy Dec 2014

Stigmatized And Getting High, Emma M. Murphy

SURGE

The first time I was asked to sell my medication was after a small party sophomore year. I was starting to fall asleep in the midst of chattering people and drunken laughter. My 12 hours of focus was up. Concerned people around me started asking why I was suddenly so sleepy and without thinking about it, my boyfriend answered “Her medication has worn off, so she’s getting kinda sleepy.” Someone asked, “What type of medication does that?!” We both froze. [excerpt]


Implementation Of Sleep Problem Screening In A Pediatric Primary Care Office, Jennifer Erin O'Donnell Dec 2014

Implementation Of Sleep Problem Screening In A Pediatric Primary Care Office, Jennifer Erin O'Donnell

Dissertations

Sleep problems, a major problem for children and their parents, are the most common complaint brought to pediatric clinicians (advanced practice nurses and other healthcare providers) attention but are often ignored and underdiagnosed in the pediatric population (Faruqui, Khubchandani, Price, Bolyard, & Reddy, 2011). “Sufficient amounts of good quality sleep are necessary for healthy development in childhood” (Bordeleau, Bernier, & Carrier, 2012, p. 254). Inadequate sleep in children has been linked to numerous adverse outcomes psychologically as well as physically (Owens, Jones, & Nash, 2011). The American Academy of Pediatrics (AAP), issued recommendations in 2002 stating screening for snoring, one …


A Microrna-1280/Jag2 Network Comprises A Novel Biological Target In High-Risk Medulloblastoma, Fengfei Wang, Marc Remke, Tze-Chen Hsieh, Lizi Wu, Cynthia Hawkins, Joseph M. Wu, Erxi Wu Dec 2014

A Microrna-1280/Jag2 Network Comprises A Novel Biological Target In High-Risk Medulloblastoma, Fengfei Wang, Marc Remke, Tze-Chen Hsieh, Lizi Wu, Cynthia Hawkins, Joseph M. Wu, Erxi Wu

NYMC Faculty Publications

Over-expression of PDGF receptors (PDGFRs) has been previously implicated in high-risk medulloblastoma (MB) pathogenesis. However, the exact biological functions of PDGFRα and PDGFRβ signaling in MB biology remain poorly understood. Here, we report the subgroup specific expression of PDGFRα and PDGFRβ and their associated biological pathways in MB tumors. c-MYC, a downstream target of PDGFRβ but not PDGFRα, is involved in PDGFRβ signaling associated with cell proliferation, cell death, and invasion. Concurrent inhibition of PDGFRβ and c-MYC blocks MB cell proliferation and migration synergistically. Integrated analysis of miRNA and miRNA targets regulated by both PDGFRβ and c-MYC reveals that increased …


Mediation Analysis Of Gestational Age, Congenital Heart Defects, And Infant Birth-Weight, Adane F. Wogu, Christopher A. Loffredo, Ionut Bebu, George Luta Dec 2014

Mediation Analysis Of Gestational Age, Congenital Heart Defects, And Infant Birth-Weight, Adane F. Wogu, Christopher A. Loffredo, Ionut Bebu, George Luta

GW Biostatistics Center

Background

In this study we assessed the mediation role of the gestational age on the effect of the infant’s congenital heart defects (CHD) on birth-weight.

Methods

We used secondary data from the Baltimore-Washington Infant Study (1981–1989). Mediation analysis was employed to investigate whether gestational age acted as a mediator of the association between CHD and reduced birth-weight. We estimated the mediated effect, the mediation proportion, and their corresponding 95% confidence intervals (CI) using several methods.

Results

There were 3362 CHD cases and 3564 controls in the dataset with mean birth-weight of 3071 (SD = 729) and 3353 (SD = 603) …


Web Tool For Estimating The Cancer Hazard Rates In Aging., Tengiz Mdzinarishvili, Alexander Sherman, Oleg Shats, Simon Sherman Dec 2014

Web Tool For Estimating The Cancer Hazard Rates In Aging., Tengiz Mdzinarishvili, Alexander Sherman, Oleg Shats, Simon Sherman

Journal Articles: Eppley Institute

A computational approach for estimating the overall, population, and individual cancer hazard rates was developed. The population rates characterize a risk of getting cancer of a specific site/type, occurring within an age-specific group of individuals from a specified population during a distinct time period. The individual rates characterize an analogous risk but only for the individuals susceptible to cancer. The approach uses a novel regularization and anchoring technique to solve an identifiability problem that occurs while determining the age, period, and cohort (APC) effects. These effects are used to estimate the overall rate, and to estimate the population and individual …


Two-Dimensional Layered Mos2 Biosensors Enable Highly Sensitive Detection Of Biomolecules, Joonhyung Lee, Piyush Dak, Yeonsung Lee, Heekyeong Park, Woong Choi, Muhammad Ashraful Alam, Sunkook Kim Dec 2014

Two-Dimensional Layered Mos2 Biosensors Enable Highly Sensitive Detection Of Biomolecules, Joonhyung Lee, Piyush Dak, Yeonsung Lee, Heekyeong Park, Woong Choi, Muhammad Ashraful Alam, Sunkook Kim

Birck and NCN Publications

We present a MoS2 biosensor to electrically detect prostate specific antigen (PSA) in a highly sensitive and label-free manner. Unlike previous MoS2-FET-based biosensors, the device configuration of our biosensors does not require a dielectric layer such as HfO2 due to the hydrophobicity of MoS2. Such an oxide-free operation improves sensitivity and simplifies sensor design. For a quantitative and selective detection of PSA antigen, anti-PSA antibody was immobilized on the sensor surface. Then, introduction of PSA antigen, into the anti-PSA immobilized sensor surface resulted in a lable-free immunoassary format. Measured off-state current of the device …


Evidence Based Falls Management Program In The Nursing Home, Deloris Jacobs Dec 2014

Evidence Based Falls Management Program In The Nursing Home, Deloris Jacobs

Graduate Theses, Dissertations, and Capstones

The cost of fall injuries for both nursing homes and patients can be staggering. Facilities can incur large financial penalties following notices of severe deficiencies from regulatory agencies and will incur substantial legal fees in the event of a wrongful injury or death lawsuit. Patients injured in falls are at risk of increased financial costs for care in the nursing home as well as a lower quality of life. They are likely to incur co-pay or coinsurance costs for care by physicians and other professional services, and costs for rehabilitative services, out of pocket expenses, medical equipment, prescription drugs, and …


A Transformational Leadership Program: A Necessity In Today’S Healthcare Environment, Kristin J. Pickerell Dec 2014

A Transformational Leadership Program: A Necessity In Today’S Healthcare Environment, Kristin J. Pickerell

Graduate Theses, Dissertations, and Capstones

A Transformational Leadership Program: A Necessity in Today’s Healthcare Environment

Abstract

Objective

The purpose of this study was to enhance the transformational leadership capabilities of the nursing leaders in a small community hospital by implementing a leadership development course.

Background

Effective nurse leaders are critical in today’s fast-changing and uncertain healthcare environment. Competent leaders positively influence the nursing work environment, staff retention, patient safety, financial viability and quality outcomes. The development of a transformational skill set needed for a nurse leader to successfully lead a team to high-quality patient care.

Methods

Pre/post intervention design, using the Leadership Practices Inventory with …


Download Entire Issue- Jefferson Interprofessional Education And Care Newsletter, Fall, 2014, Volume 5, Issue 2 Dec 2014

Download Entire Issue- Jefferson Interprofessional Education And Care Newsletter, Fall, 2014, Volume 5, Issue 2

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

Download entire issue- Jefferson Interprofessional Education and Care Newsletter, Fall, 2014, Volume 5, Issue 2


Jefferson Teamwork Observation Guide (Jtog): A Pilot Project, David George, Md, Elizabeth Speakman, Edd, Rn, Anef, Fnap, Kellie Smith, Edd, Rn, Kevin Lyons, Phd, Carolyn Giordano, Phd Dec 2014

Jefferson Teamwork Observation Guide (Jtog): A Pilot Project, David George, Md, Elizabeth Speakman, Edd, Rn, Anef, Fnap, Kellie Smith, Edd, Rn, Kevin Lyons, Phd, Carolyn Giordano, Phd

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

The critical need for students to learn to be effective members of interprofessional teams in preparation for collaborative practice-ready care provision now and in the future has been well documented1. There are increasing opportunities for students to observe interprofessional events to assist them in doing so, but often their role is passive and the teams may not demonstrate the highest level of patient-centered care, minimizing the student learning.


Developing An Open Educational Resource For Interprofessional Education (Ipe), Susanne P. Boyle, Bsc, Msc, Phd, Fhea, Matthew Ramirez, Lynn Sheridan Dec 2014

Developing An Open Educational Resource For Interprofessional Education (Ipe), Susanne P. Boyle, Bsc, Msc, Phd, Fhea, Matthew Ramirez, Lynn Sheridan

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

A recent review of pre-qualifying interprofessional education in the UK reported the practical challenges of synchronising interprofessional education1. Whilst it was noted that online interprofessional courses were developed primarily to overcome timetabling conflicts of students and clinicians from various health professions, it was recognised that a blended learning approach with appropriate student support could enable an effective interprofessional education experience with lower running costs and reduced disruption. It was found, however, that despite the ubiquity of e-learning in interprofessional education there seemed to be less sharing than expected1.


Ipe Grand Rounds: A Student-Led Initiative, Claire Sokas, Chelsea Gorman Dec 2014

Ipe Grand Rounds: A Student-Led Initiative, Claire Sokas, Chelsea Gorman

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

Interprofessional Education (IPE) Grand Rounds is an innovative student-run initiative designed specifically to increase the clinical relevance of IPE for all health professions students. By creating new opportunities for students from medicine, nursing, physical therapy, occupational therapy, couple and family therapy, physician assistant and pharmacy to interact with health professionals who are actively participating in interprofessional work environments, the IPE Grand Rounds program allows students to develop a more complete picture of what it means to be a member of a collaborative practice team. During these sessions, students and panelists discuss both the benefits of working with team members from …


Successful Implementation Of The Abcdef Bundle In The Micu Through Interprofessional Collaboration And Teamwork, Julie Rogan, Rn, Msn, Accns-Ag, Aocns, Ccrn, Steven W. Gudowski, Rrt, Cara Mcdaniel, Pharmd, Bcps Dec 2014

Successful Implementation Of The Abcdef Bundle In The Micu Through Interprofessional Collaboration And Teamwork, Julie Rogan, Rn, Msn, Accns-Ag, Aocns, Ccrn, Steven W. Gudowski, Rrt, Cara Mcdaniel, Pharmd, Bcps

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

Earlier this year, members of the medical intensive care unit (MICU) attended an interprofessional workshop that utilized Awakening/Breathing/Choice of Sedation/Delirium/Early Mobility (ABCDE) bundle simulation combined with TeamSTEPPS training to empower care givers to advocate for patient safety while optimizing patient care. The ABCDE bundle is an evidence-based tool designed to implement pain, agitation, and delirium guideline recommendations into routine practice. To further improve patient safety and outcomes and build upon the ABCDE concept, the MICU team developed an interprofession-al practice project by adding routine assessment of need for indwelling Foley catheters to their daily work list, creating the “ABCDEF” bundle.


From The Editors, Elizabeth Speakman, Edd, Rn, Anef, Fnap, Christine Arenson, Md, Lauren Collins, Md, Shoshana Sicks, Edm Dec 2014

From The Editors, Elizabeth Speakman, Edd, Rn, Anef, Fnap, Christine Arenson, Md, Lauren Collins, Md, Shoshana Sicks, Edm

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

Welcome to the Fall 2014 edition of the Jefferson Interprofessional Education and Care Newsletter. It has been a busy Fall at Jefferson and we are excited to share several new developments which have been pushing the envelope in IPE. In October, we hosted our 4th biennial conference, Interprofessional Care for the 21st Century: Redefining Education and Practice. This year we had a record number of conference participants and presenters joining us from a variety of national and international academic and service organizations. Our keynote speakers, Dr. George Thibault, President, Josiah Macy Jr Foundation; Dr. Barbara Brandt, Director, National Center for …


The Use Of An Orthotic Garment System On A Pediatric Patient With Mitochondrial Disease Complex 1+3: A Case Report, Stephanie Sheehan Dec 2014

The Use Of An Orthotic Garment System On A Pediatric Patient With Mitochondrial Disease Complex 1+3: A Case Report, Stephanie Sheehan

Case Report Posters

Background: Mitochondrial Disease (MD) is a progressive and debilitating disease that is characterized by a loss of efficiency in the electron transport chain and reductions in the synthesis of high energy molecules such as ATP. Orthotic garment systems also referred to as “TheraTogs®”, have been designed to act as a continuous somatosensory guide for proper functional alignment. Theratogs have been used in the pediatric population to treat Cerebral Palsy and Down Syndrome with excellent results but there is no known research regarding the benefits of TheraTogs® in individuals with MD. Purpose: To investigate the use of the TheraTogs® System for …


2014 December 16 - Medical Student Education Committee Meeting Minutes, Medical Student Education Committee, East Tennessee State University Dec 2014

2014 December 16 - Medical Student Education Committee Meeting Minutes, Medical Student Education Committee, East Tennessee State University

Medical Student Education Committee Minutes

No abstract provided.


Systems Biology Investigation Of Camp Modulation To Increase Smn Levels For The Treatment Of Spinal Muscular Atrophy., Sean G Mack, Daniel J Cook, Prasad Dhurjati, Matthew E R Butchbach Dec 2014

Systems Biology Investigation Of Camp Modulation To Increase Smn Levels For The Treatment Of Spinal Muscular Atrophy., Sean G Mack, Daniel J Cook, Prasad Dhurjati, Matthew E R Butchbach

Department of Pediatrics Faculty Papers

Spinal muscular atrophy (SMA), a leading genetic cause of infant death worldwide, is an autosomal recessive disorder caused by the loss of SMN1 (survival motor neuron 1), which encodes the protein SMN. The loss of SMN1 causes a deficiency in SMN protein levels leading to motor neuron cell death in the anterior horn of the spinal cord. SMN2, however, can also produce some functional SMN to partially compensate for loss of SMN1 in SMA suggesting increasing transcription of SMN2 as a potential therapy to treat patients with SMA. A cAMP response element was identified on the SMN2 promoter, implicating cAMP …


Epithelial Cells Are Active Participants In Vocal Fold Wound Healing: An In Vivo Animal Model Of Injury, Ciara Leydon, Mitsuyoshi Imaizumi, Rebecca S. Bartlett, Sarah F. Wang, Susan L. Thibeault Dec 2014

Epithelial Cells Are Active Participants In Vocal Fold Wound Healing: An In Vivo Animal Model Of Injury, Ciara Leydon, Mitsuyoshi Imaizumi, Rebecca S. Bartlett, Sarah F. Wang, Susan L. Thibeault

Communication Disorders Faculty Publications

Vocal fold epithelial cells likely play an important, yet currently poorly defined, role in healing following injury, irritation and inflammation. In the present study, we sought to identify a possible role for growth factors, epidermal growth factor (EGF) and transforming growth factor-beta 1 (TGFβ1), in epithelial regeneration during wound healing as a necessary first step for uncovering potential signaling mechanisms of vocal fold wound repair and remodeling. Using a rat model, we created unilateral vocal fold injuries and examined the timeline for epithelial healing and regeneration during early and late stages of wound healing using immunohistochemistry (IHC). We observed time-dependent …


A More Efficient Nonparametric Test Of Symmetry Based On Overlapping Coefficient, Hani M. Samawi, Robert L. Vogel Dec 2014

A More Efficient Nonparametric Test Of Symmetry Based On Overlapping Coefficient, Hani M. Samawi, Robert L. Vogel

Biostatistics: Faculty Publications

In this paper we provide a more efficient nonparametric test of symmetry based on the empirical overlap coefficient using kernel density estimation applied to an extreme order statistics, namely extreme ranked set sampling. Our simulation investigation reveals that our proposed test of symmetry is at least as powerful as currently available tests of symmetry. Intensive simulation is conducted to examine the power of the proposed test. An illustration is provided using cardiac output and body weight of neonates in a neonatal intensive care unit.