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2014

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Full-Text Articles in Medicine and Health Sciences

College Of Public Health News, Georgia Southern University Feb 2014

College Of Public Health News, Georgia Southern University

College of Public Health: News & Publications

  • Exercise Self-Efficacy in Pregnant Women


Community Health News, Georgia Southern University Feb 2014

Community Health News, Georgia Southern University

Health Policy & Community Health: News & Publications (2011-2018)

  • Exercise Self-Efficacy in Pregnant Women


What's Happening: February 24, 2014, Maine Medical Center Feb 2014

What's Happening: February 24, 2014, Maine Medical Center

What's Happening

No abstract provided.


Attention Deficit Associated With Early Life Interictal Spikes In A Rat Model Is Improved With Acth, Amanda E. Hernan, Abigail Alexander, Pierre-Pascal Lenck-Santini, Rod C. Scott Feb 2014

Attention Deficit Associated With Early Life Interictal Spikes In A Rat Model Is Improved With Acth, Amanda E. Hernan, Abigail Alexander, Pierre-Pascal Lenck-Santini, Rod C. Scott

Dartmouth Scholarship

Children with epilepsy often present with pervasive cognitive and behavioral comorbidities including working memory impairments, attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder. These non-seizure characteristics are severely detrimental to overall quality of life. Some of these children, particularly those with epilepsies classified as Landau-Kleffner Syndrome or continuous spike and wave during sleep, have infrequent seizure activity but frequent focal epileptiform activity. This frequent epileptiform activity is thought to be detrimental to cognitive development; however, it is also possible that these IIS events initiate pathophysiological pathways in the developing brain that may be independently associated with cognitive deficits. These …


Développement D’Un Indice Radiologique Représentatif De La Fonction De L’Épaule Chez Des Travailleurs Souffrant De Rupture De La Coiffe Des Rotateurs, Nicola Hagemeister, Pierre-Yves Lagacé, Joan Hereter Gregori, Laurence Marck, Dominique Rouleau, Nathalie Bureau, Patrice Tétreault, André Roy, Fidaa Al-Shakfa Feb 2014

Développement D’Un Indice Radiologique Représentatif De La Fonction De L’Épaule Chez Des Travailleurs Souffrant De Rupture De La Coiffe Des Rotateurs, Nicola Hagemeister, Pierre-Yves Lagacé, Joan Hereter Gregori, Laurence Marck, Dominique Rouleau, Nathalie Bureau, Patrice Tétreault, André Roy, Fidaa Al-Shakfa

Rapports de recherche scientifique

Les problèmes chroniques de douleur et de perte de fonction de l’épaule touchent jusqu’à 20 % des adultes (Pope, Croft et coll., 1997). La proportion serait encore plus élevée chez les adultes âgés de plus de 50 ans. Au Québec, la Commission de la santé et de la sécurité au travail du Québec (CSST) rapporte que, pour les années 2003 à 2006, les lésions à l'épaule représentaient 39% des 32 549 lésions inflammatoires dues à un travail répétitif ou à un traumatisme. Les lésions à l'épaule ont requis en moyenne 75,4 jours d'absence du travail et 4 533 $ en …


Medical School Watercooler Newsletter - February 23, 2014, Lindsey Lyle Feb 2014

Medical School Watercooler Newsletter - February 23, 2014, Lindsey Lyle

Watercooler Newsletter

This is the February 23, 2014 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents Include:

  • USA Neurology to Host Spring Symposium
  • USA Medical Student Matches Early in Ophthalmology
  • RSVP Today - 2014 Oncology Outlook
  • Med School Café - Expert Advice for the Community
  • March 6 DSS to Feature Dr. Christine M. Szymanski


Kentuckiana Camp And Hospital Council (Sc 2812), Manuscripts & Folklife Archives Feb 2014

Kentuckiana Camp And Hospital Council (Sc 2812), Manuscripts & Folklife Archives

Manuscript Collection Finding Aids

Finding aid only for Manuscripts Small Collection 2812. Minutes of the quarterly meeting of the Kentuckiana Camp and Hospital Council, held In Louisville, Kentucky on 22 October 1945. Includes a list of gifts from various Council chapters and a discussion about the continuing need for postwar assistance to hospitalized soldiers.


Gender Differences In Perceptions And Self-Reported Driving Behaviors Among Teenagers. (Poster), Gavin C. Barr Jr. Md, Kathleen E. Kane Md, Robert D. Barraco Md, Timarie Rayburg Do, Lauren Dugan Do, Chadd K. Kraus Do, Mph, Marna R. Greenberg Do, Mph, Facep, Valerie Rupp Rn, Bsn, Kimberly Hamilton, Bryan G. Kane Md Feb 2014

Gender Differences In Perceptions And Self-Reported Driving Behaviors Among Teenagers. (Poster), Gavin C. Barr Jr. Md, Kathleen E. Kane Md, Robert D. Barraco Md, Timarie Rayburg Do, Lauren Dugan Do, Chadd K. Kraus Do, Mph, Marna R. Greenberg Do, Mph, Facep, Valerie Rupp Rn, Bsn, Kimberly Hamilton, Bryan G. Kane Md

Department of Emergency Medicine

No abstract provided.


A Statewide Survey Of Institutional Trauma Human Resource Allocation And Associated Patient Mortality, Bryan G. Kane Md, Quincy Gerrald Do, Catherine Fischer Do, Kevin Vong Do, Mary Sibley Do, Justin Binstead Do Feb 2014

A Statewide Survey Of Institutional Trauma Human Resource Allocation And Associated Patient Mortality, Bryan G. Kane Md, Quincy Gerrald Do, Catherine Fischer Do, Kevin Vong Do, Mary Sibley Do, Justin Binstead Do

Department of Emergency Medicine

No abstract provided.


Does Destination Determine Destiny? A Statewide Analysis Of Trauma Center Mortality, Bryan G. Kane Md, Quincy Gerrald Do, Catherine Fischer Do, Kevin Vong Do, Mary Sibley Do, Justin Binstead Do Feb 2014

Does Destination Determine Destiny? A Statewide Analysis Of Trauma Center Mortality, Bryan G. Kane Md, Quincy Gerrald Do, Catherine Fischer Do, Kevin Vong Do, Mary Sibley Do, Justin Binstead Do

Department of Emergency Medicine

No abstract provided.


Introduction Of Evidence-Based Diagnostic Order Sets In An Electronic Medical Record Is Associated With An Increase In Laboratory Orders, Bryan G. Kane Md, Justin Arnold Do, Joshua Morrison Do, Ryan Southworth Do, William Greenhut Do, Will Russell Do, Jeremy Selley Do, Michael Stanley Do Feb 2014

Introduction Of Evidence-Based Diagnostic Order Sets In An Electronic Medical Record Is Associated With An Increase In Laboratory Orders, Bryan G. Kane Md, Justin Arnold Do, Joshua Morrison Do, Ryan Southworth Do, William Greenhut Do, Will Russell Do, Jeremy Selley Do, Michael Stanley Do

Department of Emergency Medicine

No abstract provided.


Money Follows The Person (Mfp) Rebalancing Demonstration: A Work In Progress, Carol O'Shaughnessy Feb 2014

Money Follows The Person (Mfp) Rebalancing Demonstration: A Work In Progress, Carol O'Shaughnessy

National Health Policy Forum

In recent years, federal and state policy efforts have expanded opportunities for people to live in home- and community-based settings rather than in nursing homes and other institutions. As part of the Deficit Reduction Act of 2005, Congress enacted the Money Follows the Person Rebalancing (MFP) program, a Medicaid demonstration to help people who need long-term services and supports (LTSS) transition from nursing homes and other institutions to their own homes or other community settings. The Patient Protection and Affordable Care Act of 2010 extended the program through September 30, 2016. Now in its eighth year of operation, MFP grants …


The Health Commons: A Journey Into Metis, Kathleen M. Clark Feb 2014

The Health Commons: A Journey Into Metis, Kathleen M. Clark

Theses and Graduate Projects

The importance of doctorate prepared transcultural nurses to be immersed in local communities is crucial in order to gain understanding into cultural practices and health disparities while building relationships across cultural barriers. With the current changes in health care, the emphasis on community engagement is coming to the forefront. It is crucial that advanced practice nurses be involved with these changes in ensure that the community is involved with the creation of these projects and that changes originate as a grassroots effort. The importance of relationship building and mutuality are vital in components of working with local communities. This project …


Public Health In Southeast Asia: Focus On Adolescent Health Research, Randy M. Page Feb 2014

Public Health In Southeast Asia: Focus On Adolescent Health Research, Randy M. Page

Journal of Undergraduate Research

Outcome 1: Students will develop research and presentation skills and gain confidence in their abilities. This project directed students to work on research conducted in Thailand focusing on adolescent body image and smoking. Students participated in research planning, collecting data and making sense of results, constructing data tables, translating research instruments, developing presentations, presenting findings at international conferences, and developing a manuscript for submission. A survey instrument was constructed to assess appearance-related social pressure, body weight satisfaction, and weight loss/maintenance behaviors in adolescents. Students worked with researchers in Thailand to translate the instrument from English to Thai, and through the …


Exacerbation Of Celecoxib-Induced Renal Injury By Concomitant Administration Of Misoprostol In Rats, Dustin L. Cooper, Derek E. Murrell, Christopher M. Conder, Victoria E. Palau, Grace E. Campbell, Shaun P. Lynch, James W. Denham, Angela V. Hanley, Kenny W. Bullins, Peter C. Panus, Krishna Singh, Sam Harirforoosh Feb 2014

Exacerbation Of Celecoxib-Induced Renal Injury By Concomitant Administration Of Misoprostol In Rats, Dustin L. Cooper, Derek E. Murrell, Christopher M. Conder, Victoria E. Palau, Grace E. Campbell, Shaun P. Lynch, James W. Denham, Angela V. Hanley, Kenny W. Bullins, Peter C. Panus, Krishna Singh, Sam Harirforoosh

Pharmacy Faculty Articles and Research

Nonsteroidal anti-inflammatory drugs (NSAIDs) can produce adverse effects by inhibiting prostaglandin (PG) synthesis. A PGE1 analogue, misoprostol, is often utilized to alleviate NSAID-related gastrointestinal side effects. This study examined the effect of misoprostol on celecoxib renal toxicity. Additionally, the effects of these drugs on cardiovascular parameters were evaluated. Four randomized rat groups were orally gavaged for 9 days, two groups receiving vehicle and two groups receiving misoprostol (100 µg/kg) twice daily. Celecoxib (40 mg/kg) was co-administered once daily to one vehicle and one misoprostol group from days 3 to 9. Urine and blood samples were collected and blood pressure parameters …


Genome-Wide Methylation Analyses In Glioblastoma Multiforme, Rose K. Lai, Yanwen Chen, Xiaowei Guan, Darryl Nousome, Charu Sharma, Peter Canoll, Jeffrey Bruce, Andrew E. Sloan, Etty Cortes, Jean-Paul Vonsattel, Tao Su, Lissette Delgado-Cruzata, Irina Gurvich, Regina M. Santella, Quinn Ostrom, Annette Lee, Peter Gregersen, Jill Barnholtz-Sloan Feb 2014

Genome-Wide Methylation Analyses In Glioblastoma Multiforme, Rose K. Lai, Yanwen Chen, Xiaowei Guan, Darryl Nousome, Charu Sharma, Peter Canoll, Jeffrey Bruce, Andrew E. Sloan, Etty Cortes, Jean-Paul Vonsattel, Tao Su, Lissette Delgado-Cruzata, Irina Gurvich, Regina M. Santella, Quinn Ostrom, Annette Lee, Peter Gregersen, Jill Barnholtz-Sloan

Publications and Research

Few studies had investigated genome-wide methylation in glioblastoma multiforme (GBM). Our goals were to study differential methylation across the genome in gene promoters using an array-based method, as well as repetitive elements using surrogate global methylation markers. The discovery sample set for this study consisted of 54 GBM from Columbia University and Case Western Reserve University, and 24 brain controls from the New York Brain Bank. We assembled a validation dataset using methylation data of 162 TCGA GBM and 140 brain controls from dbGAP. HumanMethylation27 Analysis Bead-Chips (Illumina) were used to interrogate 26,486 informative CpG sites in both the discovery …


Today - February 21, 2014, Loma Linda University Health Feb 2014

Today - February 21, 2014, Loma Linda University Health

TODAY

Inside this issue:

-- Jackie Evancho to perform with San Bernardino Symphony for benefit concert at LLUCH Gala
-- Loma Linda University is home to five Gates Scholars
-- Covered California holds regional kickoff at LLUH
-- Alumnus and emeritus professor tells stories of Christian medicine in new book
-- Five-K Walk/Run/Roll and International Food Festival to bookend 'Power of Inclusion' Conference at LLUH
-- Paralympic hopeful finds ways to Live It in his olympic quest
-- CAPS program recognized by San Bernardino County
-- A complex collaboration
-- Evening Rounds authors to take part in book signing
-- New …


Serum And Glucocorticoid-Inducible Kinase1 Increases Plasma Membrane Wt-Cftr In Human Airway Epithelial Cells By Inhibiting Its Endocytic Retrieval, Jennifer M. Bomberger, Bonita A. Coutermarsh, Roxanna L. Barnaby, J. Denry Sato, M. Christine Chapline, Bruce A. Stanton Feb 2014

Serum And Glucocorticoid-Inducible Kinase1 Increases Plasma Membrane Wt-Cftr In Human Airway Epithelial Cells By Inhibiting Its Endocytic Retrieval, Jennifer M. Bomberger, Bonita A. Coutermarsh, Roxanna L. Barnaby, J. Denry Sato, M. Christine Chapline, Bruce A. Stanton

Dartmouth Scholarship

Background: Chloride (Cl) secretion by the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) located in the apical membrane of respiratory epithelial cells plays a critical role in maintenance of the airway surface liquid and mucociliary clearance of pathogens. Previously, we and others have shown that the serum and glucocorticoid-inducible kinase-1 (SGK1) increases wild type CFTR (wt-CFTR) mediated Cl transport in Xenopus oocytes by increasing the amount of wt-CFTR protein in the plasma membrane. However, the effect of SGK1 on the membrane abundance of wt-CFTR in airway epithelial cells has not been examined, and the mechanism whereby SGK1 increases membrane wt-CFTR has …


Computational Health Science Collaborative: Interdisciplinary Mentoring For Public Health And Computer Science Students, Michael D. Barnes Feb 2014

Computational Health Science Collaborative: Interdisciplinary Mentoring For Public Health And Computer Science Students, Michael D. Barnes

Journal of Undergraduate Research

Computational health science, as we define it, represents the application of innovative computer science tools, including social media and data mining, to addressing health-­‐ related questions and problems. With multidisciplinary student mentoring as our aim, we have established the BYU Computational Health Science Research Collaborative (CHeSRC), which integrates the analytical strengths and skills of health scientists and computer scientists, supported by complementary expertise from other researchers, practitioners, and disciplines as applicable (http://dml.cs.byu.edu/chs/). As stated on the CHeSRC website, our mission is to better understand how technology can affect human interactions and enhance supporting environments by conducting innovative research that will …


Conference Learnings, Anne Brown Rn, Cpan Feb 2014

Conference Learnings, Anne Brown Rn, Cpan

Patient Care Services / Nursing

No abstract provided.


Conference Learnings, Anne Brown Rn, Cpan Feb 2014

Conference Learnings, Anne Brown Rn, Cpan

Patient Care Services / Nursing

No abstract provided.


The Santa Clara,2014-02-20, Santa Clara University Feb 2014

The Santa Clara,2014-02-20, Santa Clara University

The Santa Clara

No abstract provided.


Factors Influencing Breast Cancer Screening In Low-Income African Americans In Tennessee, Kushal Patel, Mohamed Kanu, Jianguo Liu, Brea Bond, Elizabeth Brown, Elizabeth Williams, Rosemary Theriot, Stephanie Bailey, Maureen Sanderson, Margaret Hargreaves Feb 2014

Factors Influencing Breast Cancer Screening In Low-Income African Americans In Tennessee, Kushal Patel, Mohamed Kanu, Jianguo Liu, Brea Bond, Elizabeth Brown, Elizabeth Williams, Rosemary Theriot, Stephanie Bailey, Maureen Sanderson, Margaret Hargreaves

Public Health, Health Administration, and Health Sciences Faculty Research

This study examined demographic and lifestyle factors that influenced decisions and obstacles to being screened for breast cancer in low-income African Americans in three urban Tennessee cities. As part of the Meharry Community Networks Program (CNP) needs assessment, a 123-item community survey was administered to assess demographic characteristics, health care access and utilization, and screening practices for various cancers in low-income African Americans. For this study, only African American women 40 years and older (n = 334) were selected from the Meharry CNP community survey database. There were several predictors of breast cancer screening such as marital status and having …


Mentoring Nursing Students In A Nutritional Improvement Study In Ecuador, Sheri P. Palmer Feb 2014

Mentoring Nursing Students In A Nutritional Improvement Study In Ecuador, Sheri P. Palmer

Journal of Undergraduate Research

The nutritional improvement study in Ecuador has been a worthwhile endeavor that has enabled many nursing students to participate. Students have been able to participate in actual data collection and data entry, as well as seeing and discussing results from previous years of the study. Students work with the schoolchildren with whom this study affects and can be a vital link in the progress of the research. The mentoring of these students in this important research work has helped them realize the significance of improving global health.


A Randomized Trial Of Bevacizumab For Newly Diagnosed Glioblastoma., Mark R Gilbert, James J Dignam, Terri S Armstrong, Jeffrey S Wefel, Deborah T Blumenthal, Michael A Vogelbaum, Howard Colman, Arnab Chakravarti, Stephanie Pugh, Minhee Won, Robert Jeraj, Paul D Brown, Kurt A Jaeckle, David Schiff, Volker W Stieber, David G Brachman, Maria Werner-Wasik, Ivo W Tremont-Lukats, Erik P Sulman, Kenneth D Aldape, Walter J Curran, Minesh P Mehta Feb 2014

A Randomized Trial Of Bevacizumab For Newly Diagnosed Glioblastoma., Mark R Gilbert, James J Dignam, Terri S Armstrong, Jeffrey S Wefel, Deborah T Blumenthal, Michael A Vogelbaum, Howard Colman, Arnab Chakravarti, Stephanie Pugh, Minhee Won, Robert Jeraj, Paul D Brown, Kurt A Jaeckle, David Schiff, Volker W Stieber, David G Brachman, Maria Werner-Wasik, Ivo W Tremont-Lukats, Erik P Sulman, Kenneth D Aldape, Walter J Curran, Minesh P Mehta

Department of Radiation Oncology Faculty Papers

BACKGROUND: Concurrent treatment with temozolomide and radiotherapy followed by maintenance temozolomide is the standard of care for patients with newly diagnosed glioblastoma. Bevacizumab, a humanized monoclonal antibody against vascular endothelial growth factor A, is currently approved for recurrent glioblastoma. Whether the addition of bevacizumab would improve survival among patients with newly diagnosed glioblastoma is not known.

METHODS: In this randomized, double-blind, placebo-controlled trial, we treated adults who had centrally confirmed glioblastoma with radiotherapy (60 Gy) and daily temozolomide. Treatment with bevacizumab or placebo began during week 4 of radiotherapy and was continued for up to 12 cycles of maintenance chemotherapy. …


Nuclear Receptor 4a3 (Nr4a3) Regulates Murine Mast Cell Responses And Granule Content, Gianni Garcia-Faroldi, Fabio R. Melo, Dennis Bruemmer, Orla M Conneely, Gunnar Pejler, Anders Lundequist Feb 2014

Nuclear Receptor 4a3 (Nr4a3) Regulates Murine Mast Cell Responses And Granule Content, Gianni Garcia-Faroldi, Fabio R. Melo, Dennis Bruemmer, Orla M Conneely, Gunnar Pejler, Anders Lundequist

Internal Medicine Faculty Publications

Nuclear receptor 4a3 (Nr4a3) is a transcription factor implicated in various settings such as vascular biology and inflammation. We have recently shown that mast cells dramatically upregulate Nuclear receptor 4a3 upon activation, and here we investigated the functional impact of Nuclear receptor 4a3 on mast cell responses. We show that Nuclear receptor 4a3 is involved in the regulation of cytokine/chemokine secretion in mast cells following activation via the high affinity IgE receptor. Moreover, Nuclear receptor 4a3 negatively affects the transcript and protein levels of mast cell tryptase as well as the mast cell’s responsiveness to allergen. Together, these findings identify …


Fundamentals Of Lung Auscultation, Abraham Bohadana, Gabriel Izbicki, Steve S. Kraman Feb 2014

Fundamentals Of Lung Auscultation, Abraham Bohadana, Gabriel Izbicki, Steve S. Kraman

Internal Medicine Faculty Publications

Chest auscultation has long been considered a useful part of the physical examination, going back to the time of Hippocrates. However, it did not become a widespread practice until the invention of the stethoscope by René Laënnec in 1816, which made the practice convenient and hygienic.1 During the second half of the 20th century, technological advances in ultrasonography, radiographic computed tomography (CT), and magnetic resonance imaging shifted interest from lung auscultation to imaging studies, which can detect lung disease with an accuracy never previously imagined. However, modern computer-assisted techniques have also allowed precise recording and analysis of lung sounds, prompting …


A Modified Generalized Fisher Method For Combining Probabilities From Dependent Tests., Hongying Dai, J Steven Leeder, Yuehua Cui Feb 2014

A Modified Generalized Fisher Method For Combining Probabilities From Dependent Tests., Hongying Dai, J Steven Leeder, Yuehua Cui

Manuscripts, Articles, Book Chapters and Other Papers

Rapid developments in molecular technology have yielded a large amount of high throughput genetic data to understand the mechanism for complex traits. The increase of genetic variants requires hundreds and thousands of statistical tests to be performed simultaneously in analysis, which poses a challenge to control the overall Type I error rate. Combining p-values from multiple hypothesis testing has shown promise for aggregating effects in high-dimensional genetic data analysis. Several p-value combining methods have been developed and applied to genetic data; see Dai et al. (2012b) for a comprehensive review. However, there is a lack of investigations conducted for dependent …


N402 Care Of The Veteran Patient In Rural, Ron Ulberg, Kent Blad Feb 2014

N402 Care Of The Veteran Patient In Rural, Ron Ulberg, Kent Blad

Journal of Undergraduate Research

The academic objectives of the MEG proposal were met and exceeded. Specifically, students were exposed to local and national venues in which Veterans and their history are prevalent. Examples of this include visits by the students and faculty to Walter Reed National Military Medical Center, VA Medical Center War Related Injury and Illness Study Center, Arlington National Cemetery, US Capitol, Lincoln Memorial, Washington Memorial, WW I Memorial, WW II Memorial, Korean War Memorial, Vietnam War Memorial, Museum of American History, etc. We also met with Senator Mike Lee from the State of Utah to discuss issues pertaining to our Veterans.


Mentoring Nursing Students In A Nutritional Improvement Study In Ecuador, Sheri P. Palmer Feb 2014

Mentoring Nursing Students In A Nutritional Improvement Study In Ecuador, Sheri P. Palmer

Journal of Undergraduate Research

The nutritional improvement study in Ecuador has been a worthwhile endeavor that has enabled many nursing students to participate. Students have been able to participate in actual data collection and data entry, as well as seeing and discussing results from previous years of the study. Students work with the schoolchildren with whom this study affects and can be a vital link in the progress of the research. The mentoring of these students in this important research work has helped them realize the significance of improving global health.