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2014

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Articles 4171 - 4200 of 9579

Full-Text Articles in Medicine and Health Sciences

Characterization Of T-Bet And Eomes In Peripheral Human Immune Cells., James J. Knox, Gabriela L. Cosma, Michael R. Betts, Laura M. Mclane May 2014

Characterization Of T-Bet And Eomes In Peripheral Human Immune Cells., James J. Knox, Gabriela L. Cosma, Michael R. Betts, Laura M. Mclane

Department of Microbiology and Immunology Faculty Papers

The T-box transcription factors T-bet and Eomesodermin (Eomes) have been well defined as key drivers of immune cell development and cytolytic function. While the majority of studies have defined the roles of these factors in the context of murine T-cells, recent results have revealed that T-bet, and possibly Eomes, are expressed in other immune cell subsets. To date, the expression patterns of these factors in subsets of human peripheral blood mononuclear cells beyond T-cells remain relatively uncharacterized. In this study, we used multiparametric flow cytometry to characterize T-bet and Eomes expression in major human blood cell subsets, including total CD4(+) …


Assessing Function And Endurance In Adults With Spinal And Bulbar Muscular Atrophy: Validity Of The Adult Myopathy Assessment Tool, Michael O. Harris-Love, Lindsey E. Rhodes, Galen Joe, Joseph A. Shrader, Sungyoung Auh, Cheunju Chen, Li Li, Ellen Levy, Todd E. Davenport, Nicholas Diprospero, Kenneth H. Fischbeck May 2014

Assessing Function And Endurance In Adults With Spinal And Bulbar Muscular Atrophy: Validity Of The Adult Myopathy Assessment Tool, Michael O. Harris-Love, Lindsey E. Rhodes, Galen Joe, Joseph A. Shrader, Sungyoung Auh, Cheunju Chen, Li Li, Ellen Levy, Todd E. Davenport, Nicholas Diprospero, Kenneth H. Fischbeck

School of Pharmacy Faculty Articles

Purpose. The adult myopathy assessment tool (AMAT) is a performance-based battery comprised of functional and endurance subscales that can be completed in approximately 30 minutes without the use of specialized equipment. The purpose of this study was to determine the construct validity and internal consistency of the AMAT with a sample of adults with spinal and bulbar muscular atrophy (SBMA). Methods. AMAT validity was assessed in 56-male participants with genetically confirmed SBMA (mean age, 53 ± 10 years). The participants completed the AMAT and assessments for disease status, strength, and functional status. Results. Lower AMAT scores were associated with longer …


The Role Of Cytoprotective And Non-Protective Autophagy In Radiation Sensitivity In Breast Tumor Cells, Jade Le May 2014

The Role Of Cytoprotective And Non-Protective Autophagy In Radiation Sensitivity In Breast Tumor Cells, Jade Le

Theses and Dissertations

In general, ionizing radiation promotes cytoprotective autophagy in a majority of breast tumor cells. Previous studies from our laboratory indicated that radiation (5x2 Gy) induces cytoprotective autophagy in MCF-7 cells. In the current work, inhibition of autophagy by silencing of Beclin-1 in MCF-7 cells resulted in an increase in sensitivity to radiation based both on cell number and clonogenic survival; however, there was no increase in apoptosis and the basis for this sensitization is currently under investigation. Unexpectedly, enhancement of autophagy by silencing of Bcl-2 also led to an increase in sensitivity to radiation, possibly through the conversion of cytoprotective …


Effects Of Music Intervention On The Patient’S Perception Of Pain After Knee Replacement Surgery, Heather E. Hooks May 2014

Effects Of Music Intervention On The Patient’S Perception Of Pain After Knee Replacement Surgery, Heather E. Hooks

Electronic Theses and Dissertations

The purpose of this study was to determine whether therapeutic music affects the patient’s perception of pain, postoperative day 1 after knee replacement surgery in an inpatient hospital. In addition to the patient’s pain levels, the study was an analysis of the quantity of opioids the patient was requested, the length of stay, and the physiological parameters, which included blood pressure, heart rate, respiratory rate, and oxygen saturation. Sixty knee replacement patients were randomly placed in the music group or the quiet group. The Faces Pain Scale Revised with Numeric Rating Scale was used to measure pain levels. Statistical analysis …


Survey Of Dental Hygienists’ Attitudes And Support Of The Proposed Dually Accredited Advanced Dental Therapist, Deborah S. Mcbride May 2014

Survey Of Dental Hygienists’ Attitudes And Support Of The Proposed Dually Accredited Advanced Dental Therapist, Deborah S. Mcbride

Electronic Theses and Dissertations

The proposed dually licensed advanced dental therapy program, a graduate level curriculum created by the American Dental Hygienists’ Association (ADHA) encompassing both dental hygiene and basic restorative procedures, creates an innovative career path in dental hygiene and increases the standing of the dental hygienist from an auxiliary role to an independent midlevel dental practitioner. Data were gathered via an online anonymous survey tool from Massachusetts registered dental hygienists to assess support of this proposed curriculum by practicing hygienists. Eighty-seven percent of survey respondents are in agreement that the scope of dental hygiene responsibilities should increase with level of education, and …


Developing A Website Of Occupation-Based Resources For Healthy Aging At Dominican University Of California, David Aizpuru, Kevin Urquhart Brown, Beverly Posqdas Deguzman, Cournety Brooke Mcintosh May 2014

Developing A Website Of Occupation-Based Resources For Healthy Aging At Dominican University Of California, David Aizpuru, Kevin Urquhart Brown, Beverly Posqdas Deguzman, Cournety Brooke Mcintosh

Dissertations, Masters Theses, Capstones, and Culminating Projects

The purpose of this project was to create a website to promote healthy aging at Dominican University of California. The website contains relevant information to promote healthy aging and publicizes Dominican University of California’s activities and programs centered around healthy aging. The design of this thesis is a virtual context project that focuses on occupation based resources for healthy aging and highlights the role of occupational therapy in health aging. The healthy aging website is currently located on the homepage of the Occupational Therapy Department of Dominican University of California website. The need for a Dominican University of California healthy …


Factors That Influence Career Choice In South African Township High School Students, Emily Ann Dodge, Martha Welderufael May 2014

Factors That Influence Career Choice In South African Township High School Students, Emily Ann Dodge, Martha Welderufael

Dissertations, Masters Theses, Capstones, and Culminating Projects

Background:The legacy of apartheid is apparent in the lack of educational resources for Black South African high school students and the occupational deprivation they experience.

Objectives of Study: To collect data on students’ perceptions of career choice in township high schools, barriers prohibiting students from engaging in a career of choice, students’ learning and listening strategies and their general hopefulness.

Methods:Non-experimental, descriptive study using both quantitative and qualitative data collection and analysis strategies.

Findings:A significant difference was found based on gender in relation to having career options and with regard to how knowledge about careers is gained. …


An Inventory Of Evidence-Based Health And Wellness Assessments For Community-Dwelling Older Adults, Elliott David Brent, Matthew Jordan Carlson May 2014

An Inventory Of Evidence-Based Health And Wellness Assessments For Community-Dwelling Older Adults, Elliott David Brent, Matthew Jordan Carlson

Dissertations, Masters Theses, Capstones, and Culminating Projects

It is estimated that by 2020 older adults will makeup one fifth of California's population. Many of these older adults are living in the community and are maintaining their independence. In order to help the older adults to maintain their independence, occupational therapists are turning to the newly emerged wellness promotion model to guide their practice. The wellness promotion model is a holistic model that addresses six domains of wellness (intellectual, spiritual, physical, social, emotional, and vocational). One of the concerns in using this model to guide the emerging practice area in occupational therapy is that there is little information …


A Randomized Controlled Trial Comparing Contrast Baths To Cryotherapy In Patients With A Wrist Fracture, Elizabeth Ashley Brown, Brittany Nicole Phipps May 2014

A Randomized Controlled Trial Comparing Contrast Baths To Cryotherapy In Patients With A Wrist Fracture, Elizabeth Ashley Brown, Brittany Nicole Phipps

Dissertations, Masters Theses, Capstones, and Culminating Projects

Cryotherapy and contrast baths are common modalities used to treat edema. Despite the fact that many hand therapists report using contrast baths with their patients, there is still little evidence on the effectiveness of them. A Randomized Controlled Trial-Repeated Measures Design was employed to compare the effectiveness of contrast baths to cryotherapy. Participants were recruited after a period of post-fracture immobilization. Blind assessors attained measurements in range of motion, pain, and edema in the 1st, 2nd, and 4th weeks. Participants were randomly assigned to either use cryotherapy or contrast baths at home during the 4-week study period. The participants in …


Developing A Data Compilation For The Marin Autism Collaborative, Sarah Jane Dequis Calub, Nicole Marie Hofeditz, Caitlin Danae Mcintyre May 2014

Developing A Data Compilation For The Marin Autism Collaborative, Sarah Jane Dequis Calub, Nicole Marie Hofeditz, Caitlin Danae Mcintyre

Dissertations, Masters Theses, Capstones, and Culminating Projects

There is a documented need for better services for those with autism spectrum disorders. Various barriers, such as availability and accessibility of services and financial barriers, prevent those who need services from obtaining them. According to the literature, using data, particularly population level data, leads to improved services. Understanding the effectiveness and ineffectiveness of services helps healthcare providers identify areas for improvement and/or capitalize on past successful methods. The purpose of this project was to provide a data compilation containing autism statistics including but not limited to prevalence, trend data, service use, and needs for the Marin Autism Collaborative (MAC). …


Skill Generalization Following Computer-Based Cognitive Retraining Among Individuals With Acquired Brain Injury, Jonathan William Alonso, Nisha E. Chadha, Jennifer Elizabeth Pulido May 2014

Skill Generalization Following Computer-Based Cognitive Retraining Among Individuals With Acquired Brain Injury, Jonathan William Alonso, Nisha E. Chadha, Jennifer Elizabeth Pulido

Dissertations, Masters Theses, Capstones, and Culminating Projects

Individuals with acquired brain injury (ABI) often experience cognitive deficits. This creates many challenges in learning or relearning skills and generalizing skills among different contexts and task demands. Computer-Based Cognitive Retraining (CBCR) is a common intervention utilized by occupational therapists to help remediate cognitive deficits in individuals with ABI. Although research has shown that CBCR programs are effective at improving cognitive domains, there is limited evidence to support generalization of these skills to functional daily living tasks. Therefore, the primary purpose of this study was to assess the occurrence of generalizing gained skills in overall cognition, attention, and memory from …


The Effectiveness Of Peer Mentoring In Helping First Year Students Develop Occupational Adaptation Skills, Lashelle Rena Rullan, Jovita Vasquez, Julia Wong May 2014

The Effectiveness Of Peer Mentoring In Helping First Year Students Develop Occupational Adaptation Skills, Lashelle Rena Rullan, Jovita Vasquez, Julia Wong

Dissertations, Masters Theses, Capstones, and Culminating Projects

Objective. To evaluate the effectiveness of peer mentoring in helping first year, first-generation college students at Dominican University of California (DUC) adapt to university life and navigate the occupational challenges experienced during the first year of college.

Method. Sixty-seven students voluntarily completed an online survey, First Year College Experience (FYCE) Survey: Adaptation to University Life. Quantitative research determined the influence of peer mentoring on the students’ adaptation and occupational performance in their transition to college. Effectiveness was determined by: 1) sense of belonging, 2) developed academic and social skills, 3) adaptive responses and strategies used, and 4) overall satisfaction with …


The Impact Of Fibromyalgia And Sensory Processing On Participation Of Daily Activities, Florina Mendoza-Battle, Regina Okun, Ashlee Sand May 2014

The Impact Of Fibromyalgia And Sensory Processing On Participation Of Daily Activities, Florina Mendoza-Battle, Regina Okun, Ashlee Sand

Dissertations, Masters Theses, Capstones, and Culminating Projects

Fibromyalgia (FM) is a pain disorder that involves a variety of symptoms including painful joints, fatigue, muscle stiffness, and sleep disturbances. Cognitive symptoms are also a hallmark of FM, which result in difficulties with thought articulation, concentration, and mental fatigue. There is a gap in research substantiating increased levels of sensory defensiveness symptoms in individuals with FM and the effects in daily life. Currently, only one research study has provided evidence of increased sensory sensitivity across multiple modalities in individuals with FM. The purpose of this research was to determine whether women with FM had increased levels of sensory defensiveness …


The Development Of A Therapeutic Listening Instrument For Allied Health: A Pilot Study, Linda Diane Roybal, Suzanne Laura Schwind, Elizabeth Jeanne Szoboszlay, Brittnee Jane Witham May 2014

The Development Of A Therapeutic Listening Instrument For Allied Health: A Pilot Study, Linda Diane Roybal, Suzanne Laura Schwind, Elizabeth Jeanne Szoboszlay, Brittnee Jane Witham

Dissertations, Masters Theses, Capstones, and Culminating Projects

Occupational therapy education programs need a method for capturing student success in learning the necessary skills of therapeutic listening prior to fieldwork. There are no formalized instruments to measure therapeutic listening knowledge and skills in occupational therapy curriculums. Listening measurement tools that currently exist have been primarily created for other professionals in the medical field. Developing a listening instrument that measures the basic knowledge and skills of students’ listening would benefit occupational therapy education programs by determining the need for additional listening training of its students. This thesis study describes a pilot study used to develop a therapeutic listening instrument. …


Understanding And Preventing Falls: Perspectives Of First Responders And Older Adults, Monica Fernandez, Anita Diep Hin, Chelsea C. Prado May 2014

Understanding And Preventing Falls: Perspectives Of First Responders And Older Adults, Monica Fernandez, Anita Diep Hin, Chelsea C. Prado

Dissertations, Masters Theses, Capstones, and Culminating Projects

OBJECTIVE. The objectives of this study were to identify characteristics of older adult fallers in a local community in Marin County, California, examine the perceptions of older adults who contacted a local fire district after a fall, examine the perceptions of first responders from a local fire district regarding falls and fall prevention, explore the degree of depression in older adult fallers, and identify strategies to prevent falls in older adults.

METHODS. This research study was an exploratory and retrospective descriptive study that utilized a mixed-method design. The researchers coded narratives from Patient Care Report (PCRs) provided by the fire …


A Qualitative Study Of The Experiences Of First-Generation Peer Mentors, Cindelle Leyson, Jessica Suzanne Taylor, Tiffany Torres May 2014

A Qualitative Study Of The Experiences Of First-Generation Peer Mentors, Cindelle Leyson, Jessica Suzanne Taylor, Tiffany Torres

Dissertations, Masters Theses, Capstones, and Culminating Projects

While there are numerous studies reporting on the benefits that mentees receive from peer mentoring, there is limited research on the benefits to mentors, particularly first-generation students (FGS). The purpose of this study was to examine the experience of mentoring from the FGS mentors’ point of view. In this qualitative, exploratory design, four FGS mentors were interviewed about their experiences with a peer-mentoring program at their university. The participants believed they developed skills in the areas of time management, communication, and setting boundaries. The participants learned about themselves and gained an understanding of how the skills they developed while mentoring …


Employment Exchange Opportunities For Teens And Adults With Autism, Rafael Garcia, Kisa Nicole Geiger, Alex Robert Shragg May 2014

Employment Exchange Opportunities For Teens And Adults With Autism, Rafael Garcia, Kisa Nicole Geiger, Alex Robert Shragg

Dissertations, Masters Theses, Capstones, and Culminating Projects

The purpose of this project was to create a resource guide which includes information about the steps an individual with autism (AS) or Asperger syndrome (ASD) must take with the Department of Rehabilitation (DOR) to gain vocational support services within Marin County. The resource guide also includes information about the variety of services available to support individuals with autism and Asperger syndrome, both from the DOR and from private agencies. The effectiveness of the resource guide is of significance as there are many young adults with autism or AS in Marin County who are transitioning from school to employment. Additionally, …


Fall Risk Evaluation Tool For Acquired Brain Injury: A Validation Of A Multifactorial Assessment: A Pilot Study, Tanya Elesia Orgill, Amanda Marie Woods, Josue Julian Zamora May 2014

Fall Risk Evaluation Tool For Acquired Brain Injury: A Validation Of A Multifactorial Assessment: A Pilot Study, Tanya Elesia Orgill, Amanda Marie Woods, Josue Julian Zamora

Dissertations, Masters Theses, Capstones, and Culminating Projects

Objective: The purpose of this study examined the reliability and validity of FRET to predict falls in community-dwelling individuals with acquired brain injuries (ABI).

Method: The target population was English speaking, community-dwelling individuals 18 years or older who have sustained an ABI. Individuals were excluded if they had neurodegenerative diseases, used a wheelchair for more than 25% of the day, or were classified as globally confused. Global confusion was assessed using the first three-questions on the Saint Louis University Mental Examination (SLUMS). A total of 12 participants were recruited for the study, two were excluded and there was one attrition. …


Motivational Interviewing At The Intersections Of Depression And Intimate Partner Violence Among African American Women, Stéphanie Wahab, Jammie Trimble, Angie Mejia, S. Renee Mitchell, Mary Jo Thomas, Vanessa Timmons, A. Star Waters, Dora Raymaker, Christina Nicolaidis May 2014

Motivational Interviewing At The Intersections Of Depression And Intimate Partner Violence Among African American Women, Stéphanie Wahab, Jammie Trimble, Angie Mejia, S. Renee Mitchell, Mary Jo Thomas, Vanessa Timmons, A. Star Waters, Dora Raymaker, Christina Nicolaidis

School of Social Work Faculty Publications and Presentations

This article focuses on design, training, and delivery of a culturally-tailored, multi-faceted intervention which used motivational interviewing (MI) and case management to reduce depression severity among African American survivors of intimate partner violence (IPV). We present the details of the intervention and discuss its implementation as a means of creating and providing culturally appropriate depression and violence services to African American women. We used a CBPR approach to develop and evaluate the multi-faceted intervention. As part of the evaluation, we collected process measures about the use of MI, assessed MI fidelity, and interviewed participants about their experiences with the program.


The Mi-2 Homolog Mit1 Actively Positions Nucleosomes Within Heterochromatin To Suppress Transcription, Kevin M. Creamer May 2014

The Mi-2 Homolog Mit1 Actively Positions Nucleosomes Within Heterochromatin To Suppress Transcription, Kevin M. Creamer

Theses and Dissertations (ETD)

Eukaryotic DNA is packaged into the nucleus in complex with proteins that regulate access and utilization of the genetic material. These DNA and protein complexes form a dynamic structure known as chromatin. Nucleosomes are the repeating unit of chromatin, and consist of DNA wrapped around an octamer of histone proteins. Nucleosomes can then be modified and spatially arranged to facilitate processes such as transcription, DNA replication, and repair. A special transcriptionally repressive chromatin structure assembles onto gene-poor, repetitive regions of the genome known as constitutive heterochromatin. Mit1 is the putative chromatin remodeling subunit of the fission yeast Snf2/HDAC repressor complex …


The Health-Related Quality Of Life Of Adults With Down Syndrome, Rebecca Jermyn Graves May 2014

The Health-Related Quality Of Life Of Adults With Down Syndrome, Rebecca Jermyn Graves

Theses and Dissertations (ETD)

Purpose. The purpose of this study was to examine the health-related quality of life (HRQOL) and factors associated with the HRQOL of adults with Down syndrome (DS) as reported by adults with DS and their caregivers. The study was designed to compare measures of HRQOL, health problems, health risks, and health-care utilization of adults with DS based on self-report with those from caregiver-report and to explore associations between HRQOL and health problems, health risks, health-care utilization, adaptive behavior, and demographic characteristics. Background. The life expectancy of individuals with DS has lengthened from approximately 30 years around 1960 to over 50 …


Dietary Counseling Practices And Perceived Barriers Among Utah Dental Hygienists, Natalie F. Carlson May 2014

Dietary Counseling Practices And Perceived Barriers Among Utah Dental Hygienists, Natalie F. Carlson

Electronic Theses and Dissertations

Diet related factors are associated with the 2 most prevalent oral diseases- caries and periodontal disease. Furthermore, there is growing evidence of a synergistic link between nutrition, systemic health, and oral health. Regardless of this evidence and in spite of recommendations by dental associations, researchers have shown the majority of dental professionals are consistently excluding nutritional screenings and dietary counseling in their dental services. The purpose of this study was to examine the nutritional screening and dietary counseling practices of Utah dental hygienists and to evaluate possible associations between various factors influencing the implementation of nutritional services. Surveys were collected …


Hand Function Evaluation For Dental Hygiene Students, Sara Taft May 2014

Hand Function Evaluation For Dental Hygiene Students, Sara Taft

Electronic Theses and Dissertations

Dental hygiene students may struggle in dental hygiene curriculum in regards to hand function. Currently, this is not an aspect dental hygiene programs screen for or have protocol in place to help students. The research in the study examined if hand function could improve with hand function exercises and if exercises improved instrumentation scores. During a 6-week pilot study, an occupational therapist tested the hand function of a cohort of dental hygiene students. The results were recorded and the students began a 6-week hand function exercise regimen. After 6 weeks the same evaluations were preformed and the pre- and posttest …


Physiologically-Based Pharmacokinetic Model For Ertapenem, Whitney Forbes May 2014

Physiologically-Based Pharmacokinetic Model For Ertapenem, Whitney Forbes

Electronic Theses and Dissertations

Ertapenem is a carbapenem used to treat a wide range of bacterial infections. What sets ertapenem apart from other carbapenems is its longer half-life which implies it need only be administered once daily. We developed a physiologically-based pharmacokinetic model for the distribution of ertapenem within the body. In the model, parameters such as human body weight and height, age, organ volumes, blood flow rates, and partition coefficients of particular tissues are used to examine the absorption, distribution, metabolism, and excretion of ertapenem. The total and free blood concentrations found were then compared to experimental data. We then examined the sensitivity …


Evaluation Of Key Components Of Draft Guidelines For The National Weather Service Tsunamireadytm Community Program, Colleen Scott May 2014

Evaluation Of Key Components Of Draft Guidelines For The National Weather Service Tsunamireadytm Community Program, Colleen Scott

Electronic Theses and Dissertations

The National Tsunami Hazard Mitigation Program partnered with the National Weather Service (NWS) in 2000 to create the TsunamiReadyTM (TR) Community program. TR is designed to help communities in coastal areas plan and prepare for tsunamis. To achieve TR recognition communities must meet certain criteria including specific emergency planning and management actions within the categories of mitigation, preparedness, response, and recovery.

This study’s purpose was to evaluate the acceptability and usefulness of key components of a proposed revised set of TR Community program guidelines. Research was guided by the Elaboration Likelihood Model (ELM) using Community Based Participatory Research methods …


Antioxidant Gene Therapy Against Neuronal Cell Death, Juliana Navarro-Yepes, Laura Zavala-Flores, Anandhan Annadurai, Fang Wang, Maciej Skotak, Namas Chandra, Ming Li, Aglaia Pappa, Daniel Martinez-Fong, Luz Maria Del Razo, Betzabet Quintanilla-Vega, Rodrigo Franco May 2014

Antioxidant Gene Therapy Against Neuronal Cell Death, Juliana Navarro-Yepes, Laura Zavala-Flores, Anandhan Annadurai, Fang Wang, Maciej Skotak, Namas Chandra, Ming Li, Aglaia Pappa, Daniel Martinez-Fong, Luz Maria Del Razo, Betzabet Quintanilla-Vega, Rodrigo Franco

Department of Psychology: Faculty Publications

Oxidative stress is a common hallmark of neuronal cell death associated with neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, as well as brain stroke/ischemia and traumatic brain injury. Increased accumulation of reactive species of both oxygen (ROS) and nitrogen (RNS) has been implicated inmitochondrial dysfunction, energy impairment, alterations in metal homeostasis and accumulation of aggregated proteins observed in neurodegenerative disorders, which lead to the activation/modulation of cell death mechanisms that include apoptotic, necrotic and autophagic pathways. Thus, the design of novel antioxidant strategies to selectively target oxidative stress and redox imbalance might represent important therapeutic approaches against neurological disorders. …


Consent For Nondiagnostic Research Biopsies: A Pilot Study Of Participant Recall And Therapeutic Orientation, Roberto Abadie, Jonathan Kimmelman, Josiane Lafleur, Trudo Lemmens, May 2014

Consent For Nondiagnostic Research Biopsies: A Pilot Study Of Participant Recall And Therapeutic Orientation, Roberto Abadie, Jonathan Kimmelman, Josiane Lafleur, Trudo Lemmens,

Department of Sociology: Faculty Publications

A growing number of clinical trials incorporate invasive procedures like nondiagnostic tumor biopsies for biomarker or pharmacodynamic analysis.1 Such invasive research procedures are ethically contentious. Tumor biopsies involve pain and complication risk,2 and at least one procedure-related death has been reported.3 However, nondiagnostic tumor biopsies obtained in the research context generally have no value for managing the participant’s medical condition. Some commentators therefore argue that research biopsies “take” from participants without “giving in return.”4 Because such procedures are conducted contrary to research participants’ medical interests, an ethical framework for enrolling patients in studies that include a research biopsy rides heavily …


การป้องกันการติดเชื้อเอชไอวี / เอดส์ด้านพฤติกรรมในกลุ่มชายที่มีเพศสัมพันธ์กับชาย, เอกชัย แดงสอาด, นันทิยา วัฒายุ, สุพินดา เรืองจิรัษเฐียร May 2014

การป้องกันการติดเชื้อเอชไอวี / เอดส์ด้านพฤติกรรมในกลุ่มชายที่มีเพศสัมพันธ์กับชาย, เอกชัย แดงสอาด, นันทิยา วัฒายุ, สุพินดา เรืองจิรัษเฐียร

Journal of Nursing Research, Innovation, and Health

No abstract provided.


ผลของโปรแกรมการให้ความรู้และการสนับสนุนทางสังคมต่อพฤติกรรมเสี่ยง โรคหลอดเลือดสมองในผู้สูงอายุโรคความดันโลหิตสูง, ปานใจ กันยะมี, ทัศนา ชูวรรธนะปกรณ์ May 2014

ผลของโปรแกรมการให้ความรู้และการสนับสนุนทางสังคมต่อพฤติกรรมเสี่ยง โรคหลอดเลือดสมองในผู้สูงอายุโรคความดันโลหิตสูง, ปานใจ กันยะมี, ทัศนา ชูวรรธนะปกรณ์

Journal of Nursing Research, Innovation, and Health

วัตถุประสงค์: เพื่อศึกษาผลของโปรแกรมการให้ความรู้และการสนับสนุนทางสังคมต่อพฤติกรรมเสี่ยง ต่อโรคหลอดเลือดสมองในผู้สูงอายุโรคความดันโลหิตสูง\n \nรูปแบบการวิจัย: การวิจัยแบบกึ่งทดลอง\n \nวิธีดําเนินการวิจัย: กลุ่มตัวอย่าง คือ ผู้สูงอายุโรคความดันโลหิตสูงที่มีอายุ 60 ปีขึ้นไป อาศัยอยู่ใน ชุมชนเขตเทศบาลเมืองน่าน จังหวัดน่าน เลือกกลุ่มตัวอย่างตามสะดวก จํานวน 40 คน แบ่งเป็นกลุ่ม ทดลอง 20 คน และกลุ่มควบคุม 20 คน โดยจับคู่กลุ่มทดลองและกลุ่มควบคุมให้มีคุณสมบัติใกล้เคียงกัน ในด้าน เพศ อายุ และระยะเวลาการเจ็บป่วย กลุ่มควบคุมได้รับการพยาบาลตามปกติ กลุ่มทดลองได้รับ โปรแกรมการให้ความรู้และการสนับสนุนทางสังคม เก็บรวบรวมข้อมูลโดยใช้แบบสอบถามพฤติกรรมเสี่ยง ต่อโรคหลอดเลือดสมอง ตรวจสอบความตรงตามเนื้อหาของเครื่องมือโดยผู้เชี่ยวชาญ 5 คน และทดสอบ ความเที่ยงของแบบวัดพฤติกรรมเสี่ยงต่อโรคหลอดเลือดสมองด้วย Cronbach's alpha coefficient ได้ ค่าเท่ากับ .84 วิเคราะห์ข้อมูลโดยใช้ ร้อยละ ค่าเฉลี่ย ส่วนเบี่ยงเบนมาตรฐาน และการทดสอบด้วยสถิติที\n \nผลการวิจัย: 1) คะแนนพฤติกรรมเสี่ยงต่อโรคหลอดเลือดสมองของผู้สูงอายุโรคความดันโลหิตสูงกลุ่ม ทดลองภายหลังเข้าร่วมโปรแกรมการให้ความรู้และการสนับสนุนทางสังคมสูงกว่าก่อนได้รับโปรแกรมฯ อย่างมีนัยสําคัญทางสถิติ (p<.01) นั่นคือ หลังได้รับโปรแกรมการให้ความรู้และการสนับสนุนทางสังคมผู้สูงอายุโรคความดันโลหิตสูงมีพฤติกรรมเสี่ยงต่อการเกิดโรคหลอดเลือดสมองน้อยกว่าก่อนเข้าร่วมโปรแกรมฯ และ 2) คะแนนพฤติกรรมเสี่ยงต่อโรคหลอดเลือดสมองของผู้สูงอายุโรคความดันโลหิตสูงกลุ่มที่เข้าร่วม โปรแกรมการให้ความรู้และการสนับสนุนทางสังคม สูงกว่ากลุ่มที่ได้รับการพยาบาลตามปกติอย่างมีนัยสําคัญทางสถิติ (p<.01) นั่นคือ ผู้สูงอายุโรคความดันโลหิตสูงที่ได้รับโปรแกรมการให้ความรู้และการ สนับสนุนทางสังคม การมีพฤติกรรมเสี่ยงต่อโรคหลอดเลือดสมองน้อยกว่ากลุ่มที่ได้รับการพยาบาลตามปกติ\n\n สรุป: โปรแกรมการให้ความรู้และการสนับสนุนทางสังคมมีประสิทธิผลในการลดพฤติกรรมเสี่ยงต่อโรคหลอดเลือดสมอง ซึ่งมีประโยชน์ในการป้องกันภาวะเสียงของผู้สูงอายุโรคความดันโลหิตสูง\n\n\n


ผลของโปรแกรมการสร้าเสริมพลังอำนาจต่อการรับรู้สมรรถนะในการดูแลตนเอง ของผู้สูงอายุโรคความดันโลหิตสูง, เสาวลักษณ์ สุขพัฒนศรีกุล, วิไลวรรณ ทองเจริญ, จันทนา รณฤทธิวิชัย, วิชชุดา เจริญกิจการ May 2014

ผลของโปรแกรมการสร้าเสริมพลังอำนาจต่อการรับรู้สมรรถนะในการดูแลตนเอง ของผู้สูงอายุโรคความดันโลหิตสูง, เสาวลักษณ์ สุขพัฒนศรีกุล, วิไลวรรณ ทองเจริญ, จันทนา รณฤทธิวิชัย, วิชชุดา เจริญกิจการ

Journal of Nursing Research, Innovation, and Health

วัตถุประสงค์: เพื่อศึกษาผลของโปรแกรมการสร้างเสริมพลังอํานาจต่อการรับรู้สมรรถนะในการดูแล ตนเองของผู้สูงอายุโรคความดันโลหิตสูง\n\n รูปแบบการวิจัย: การวิจัยกึ่งทดลอง\n \nวิธีดําเนินการวิจัย: กลุ่มตัวอย่าง คือ ผู้สูงอายุโรคความดันโลหิตสูงจํานวน 60 คน คัดเลือกกลุ่มตัวอย่าง แบบสะดวก แบ่งเป็นกลุ่มทดลอง 30 คน และกลุ่มควบคุม 30 คน เครื่องมือที่ใช้ในการทดลอง คือ โปรแกรม การสร้างเสริมพลังอํานาจตามแนวคิดของ Gibson ใช้ระยะเวลาในการศึกษา 5 สัปดาห์ เก็บรวบรวม ข้อมูลโดยใช้แบบสอบถามข้อมูลส่วนบุคคล และแบบสอบถามการรับรู้สมรรถนะในการดูแลตนเอง มีค่า ดัชนีความตรงตามเนื้อหาเท่ากับ .95 และสัมประสิทธิ์อัลฟ่าครอนบาคเท่ากับ .81 วิเคราะห์ข้อมูลโดยใช้ สถิติเชิงบรรยาย สถิติไค-สแควร์ และสถิติที\n\n ผลการวิจัย: 1) ผู้สูงอายุโรคความดันโลหิตสูงหลังได้รับโปรแกรมการสร้างเสริมพลังอํานาจมีคะแนน การรับรู้สมรรถนะในการดูแลตนเองสูงกว่าก่อนได้รับโปรแกรมฯ อย่างมีนัยสําคัญทางสถิติที่ระดับ .001\n2) ผู้สูงอายุโรคความดันโลหิตสูงกลุ่มที่ได้รับโปรแกรมการสร้างเสริมพลังอํานาจมีคะแนน การรับรู้สมรรถนะในการดูแลตนเองสูงกว่ากลุ่มที่ได้รับการพยาบาลตามปกติ อย่างมีนัยสําคัญทางสถิติที่ ระดับ .001\n \nสรุป: โปรแกรมการสร้างเสริมพลังอํานาจส่งผลให้การรับรู้สมรรถนะในการดูแลตนเองของผู้สูงอายุโรค ความดันโลหิตสูงเพิ่มขึ้น และเพิ่มสูงกว่าผู้สูงอายุโรคความดันโลหิตสูงที่ได้รับการพยาบาลตามปกติ\n