Medicine and Health Sciences Commons^™

Introduction Of A New Vaccine In Epi; What We Can Achieve From A Programme In Failure, Sana Tanzil, Tanzil Jamali, Narjis Rizvi

Community Health Sciences

No abstract provided.

Approaches To Improve Quality Of Care (Qoc) For Women And Newborns: Conclusions, Evidence Gaps And Research Priorities, Zulfiqar Ahmed Bhutta, Rehana A. Salam, Zohra S. Lassi, Anne Austin, Ana Langer

Department of Paediatrics and Child Health

Despite progress in recent years, an estimated 273,500 women died as a result of maternal causes in 2010. The burden of these deaths is disproportionately bourne by women who reside in low income countries or belong to the poorest sectors of the population of middle or high income ones, and it is particularly acute in regions where access to and utilization of facility-based services for childbirth and newborn care is lowest. Evidence has shown that poor quality of facility-based care for these women and newborns is one of the major contributing factors for their elevated rates of morbidity and mortality. …

A Double-Blind Randomized Trial Of Fish Oil To Lower Triglycerides And Improve Cardiometabolic Risk In Adolescents., Samuel S. Gidding, Carol Prospero, Jobayer Hossain, Frances Zappalla, Prabhakaran Babu Balagopal, Bonita Falkner, Peter Kwiterovich

Department of Pediatrics Faculty Papers

OBJECTIVES: To determine the efficacy of 4 g/day fish oil to lower triglycerides and impact lipoprotein particles, inflammation, insulin resistance, coagulation, and thrombosis.

STUDY DESIGN: Participants (n = 42, age 14 ± 2 years) with hypertriglyceridemia and low-density lipoprotein (LDL) cholesterol/dL were enrolled in a randomized, double-blind, crossover trial comparing 4 g of fish oil daily with placebo. Treatment interval was 8 weeks with a 4-week washout. Lipid profile, lipoprotein particle distribution and size, glucose, insulin, high-sensitivity C-reactive protein, interleukin-6, fibrinogen, plasminogen activator inhibitor-1, and thrombin generation were measured.

RESULTS: Baseline lipid profile was total cholesterol 194 (5.4) mg/dL (mean …

Association Of Gap Junction Beta 2 And Transglutaminase 1 Gene Expression With Canine Atopic Dermatitis, Gunnaporn Suriyaphol, Sirin Theerawatanasirikul, Piyarat Chansiripornchai

The Thai Journal of Veterinary Medicine

Atopic dermatitis is a common pruritic inflammatory skin disease in humans and dogs. Cell junction and cornified envelope are groups of proteins that are crucial for the formation and stability of the skin barrier. The purpose of this study was to investigate gene expression in cell junction and cornified envelope groups in canine atopic dermatitis (CAD) in small dog breeds. Skin biopsy was performed from 10 lesional CAD, 9 non-lesional CAD cases and 11 normal dogs and subjected to quantitative reverse transcription-polymerase chain reaction. Several cell junction genes were evaluated, including claudin-1, occludin, zonula occludens-1 and -2, zonula occludens-1-associated nucleic …

Development Of Sedds/Smedds Of Sweet Basil Oil And Fingerroot Oil For Using In Drinking Water For Chickens, Prapaporn Boonme, Varaporn Buraphacheep Junyaprasert

The Thai Journal of Veterinary Medicine

This study aimed to develop self-emulsifying drug delivery systems or self-microemulsifying drug delivery systems (SEDDS/SMEDDS) to thoroughly mix sweet basil oil and fingerroot oil in drinking water for chickens in order to utilize for coccidiosis prevention and treatment. Effects of surfactant and cosolvent type on the formulations were investigated. The selected formulations were then investigated for physical properties. In addition, the chemical stability of the formulations was studied by Gas Chromatography-Mass Spectrophotometry (GC-MS) after kept in three different conditions, i.e., 5±3 oC (in a refrigerator), 30±2 oC/75±5%RH, and 45±2 oC/75±5%RH, for four months. It was found that both sweet basil …

Changes In Electrophysiology, Heart Rate Variability And Proteinuria In Clinical Dogs Treated With Doxorubicin Chemotherapy, Chollada Buranakarl, Anusak Kijtawornrat, Winai Chansaisakorn, Monkon Trisiriroj, Chidchanok Ngamdamrongkiat, Thita Taecholarn, Jaruwat Sonpee, Wasinee Chanwathik

The Thai Journal of Veterinary Medicine

The objective of the study was to evaluate the effects of doxorubicin (DOX) at the dose used in clinical practice (12-25 mg/m2 body surface area) on cardiac electrophysiology and proteinuria. Nine dogs with tumors were treated with 1st dose of DOX while 6 and 3 dogs were left for 2nd and 3rd doses, respectively. Measurements of blood chemistries, blood pressure, electrocardiography, heart rate variability and proteinuria were performed after the 1st, 2nd and 3rd doses of DOX. All data were obtained the day just before the next dose was introduced. Results showed that giving 1 to 3 doses of DOX …

Monitoring Ovarian Cycles By Fecal Progesterone Analysis In Thamin Eld’S Deer Hinds (Rucervus Eldii Thamin), Orasa Phraluk, Chainarong Punkong, Ampika Thongphakdee, Boripat Siriaroonrat, Worawidh Wajjwalku, Nikorn Thongtip

The Thai Journal of Veterinary Medicine

The aims of this study were to demonstrate the effectiveness of fecal progesterone metabolite monitoring technique during estrus synchronization and to investigate fecal progesterone metabolite profile in Eld’s deer (Rucervus eldii thamin) hinds for one year (February 2009-Janurary 2010). Fecal samples from five hinds were collected weekly, subjected to hormone extraction and subsequently progesterone analysis using enzyme immunoassay (EIA). Estrus synchronization and artificial insemination were performed during breeding season (June 2009). This included an intramuscular injection of ProstaglandinF2α (5 mg) in combination with a vaginal insertion of a controlled internal drug-releasing device (CIDR type G) for 14 d. After CIDR-G …

Screening For Bacteriocin-Like Antimicrobial Activity Against Shrimp Pathogenic Vibrios And Molecular Identification Of Marine Bacteria From Otter Clam Lutraria Philippinarum, Thu Thuy Pham, Thi Hong Nhi Ho, Van Duy Nguyen

The Thai Journal of Veterinary Medicine

This study aimed to isolate marine bacteria from otter clam Lutraria philippinarum, screen for bacteriocin-like antimicrobial activity against shrimp pathogenic vibrios and identify these bacteria by molecular methods. Among a total of 128 bacterial isolates, 19 (15%) were found to produce bacteriocins against at least one of three shrimp pathogenic Vibrio strains. The highest bacteriocin production activity was shown by six strains, named H9, H18, H51, H61, H77 and H108. The antimicrobial activity of crude bacteriocin extracts from these strains was completely inactivated after proteinase K and trypsin treatment, heat-labile but relatively stable at pH 4-10. Sequencing and phylogenetic analysis …

Longitudinal Study Of Salmonella And Campylobacter Species From Two Laying Duckling Flocks In The Central Region Of Thailand, Chalermkiat Saengthongpinit, Dhanapol Nane-Siri, Pornpim Aparachita, Prapassorn Apiwannarat, Pricha Buakhao, Watcharit Bowornnantiwath, Naris Thengchaisri, Thaweesak Songserm

The Thai Journal of Veterinary Medicine

A longitudinal study was carried out to determine the prevalence of Campylobacter spp. and Salmonella spp. in two laying duckling flocks from the same parent stock. In total, 477 samples: breeding ducks (n=100), 1-day-old female ducklings (n=160), 30-day-old female ducklings (n=178), and environmental (n=39) samples isolated from incubator, soil, water, and feed, were investigated. Results revealed that an overall isolation of Campylobacter spp. was 27.0% (129/477). From the total of 129 positive samples, 56.6% was C. jejuni and 43.4% was C. coli. An overall isolation of Salmonella spp. was 31.0% (148/477). Eight serotypes of Salmonella enterica were identified: S. Amsterdam, …

Seminal Vesicle Carcinoma-In-Situ In An Adult Rhesus Macaque: A Case Report And Review Of The Literature, Rawiwan Imerbsin, Kesara Chumpolkulwong, Alongkorn Hanrujirakomjohn, Mana Saithasao, Sirintra Sirivisoot, Sujitra Tayamun, Laksanee Inamnuay, Eric D. Lombardini

The Thai Journal of Veterinary Medicine

A seminal vesicle carcinoma-in-situ was diagnosed as an incidental finding during histopathological evaluation of necropsy tissues in a 9 year old intact male Indian origin Rhesus macaque. The animal had been used in a series of infectious disease studies and in a terminal renal transplantation experiment over the course of its life at the Armed Forces Research Institute of Medical Sciences. Diagnosis was proffered by a board certified (ACVP) veterinary pathologist due to the microscopic appearance of the neoplasm and confirmed using immunohistochemistry. This report represents the first description of a seminal vesicle carcinoma-in-situ in a non-human primate.

Medical School Watercooler Newsletter - August 31, 2014, Lindsey Lyle

Watercooler Newsletter

This is the August 31, 2014 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents Include:

• USA Center for Lung Biology Hosts Lung Bowl
• Students: Mark Your Calendar for Jag Health and Wellness Day
• USA Welcomes Dr. Brett Baskovich
• TEDMED to be Streamed Live at USA Biomedical Library
• Basic Medical Sciences Graduate Program Student Receives Edwin R. Hughes Award
• Benefit of USA Children's Clinic Reading Program Validated Through New AAP Policy

Nurses' Perceptions After Obtaining Medical Surgical Certification, Brenda L. Case-Cook

Regis University Student Publications (comprehensive collection)

Abstract Nursing certification is designed to assess a nurse's comprehensive knowledge within their specialty area through standardized testing (ANCC, 2013). In order to obtain Medical Surgical Certification (CMSRN) applicants must have a minimum of two years of experience as a registered nurse in a medical-surgical setting, have an unencumbered RN license, and pay the required registration fee in order to sit for the exam. Many institutions are requiring nurses to have specialty certification before advancing in rank or receiving additional compensation. This capstone project examined nurses' perceptions of medical surgical nursing at one large urban hospital in the South. A …

Assessment Of Resident And Faculty Preferences For Clinical Pharmacy Services Within A Developing Family Medicine Residency Program, Kerry Haney

University Grant Program Reports

No abstract provided.

Investigating Propargyl-Linked Antifolates In Inhibiting Bacterial And Fungal Dihydrofolate Reductase, Joshua Andrade

Honors Scholar Theses

Antimicrobial agents have been invaluable in reducing illness and death associated with bacterial infection. However, over time, bacteria have evolved resistance to all major drug classes as a result of selective pressure. The advancement of new drug compounds is therefore vital. The Anderson-Wright Lab has focused on developing potent and selective inhibitors of dihydrofolate reductase (DHFR), an enzyme key in cell proliferation and survival, in several pathogenic species. The lab has found that a set of compounds, known as propargyl-linked antifolates, are DHFR inhibitors that are both biologically effective and have strong pharmacokinetic properties.

The efficacy of novel propargyl-linked antifolates …

Optimalisasi Sistem Pelayanan Kesehatan Berjenjang Pada Program Kartu Jakarta Sehat, Fachmi Idris

Kesmas

Peningkatan jumlah kunjungan pasien ke rumah sakit pada awal masa pemberlakuan program Kartu Jakarta Sehat (KJS) disebabkan belum optimalnya sistem pelayanan kesehatan berjenjang. PT Asuransi Kesehatan (PT Askes) bersama Dinas Kesehatan DKI Jakarta melakukan berbagai upaya dalam bentuk paket intervensi untuk mengoptimalkan sistem tersebut. Penelitian ini bertujuan untuk mengevaluasi efektivitas paket intervensi PT Askes dan Dinas Kesehatan DKI Jakarta dalam meningkatkan optimilisasi sistem rujukan pelayanan kesehatan. Penelitian ini menggunakan survei potong lintang dengan metode pengambilan sampel acak pada puskesmas di DKI Jakarta terhadap hasil intervensi PT Askes. Hasil intervensi diukur melalui wawancara pada kepala puskesmas atau petugas yang mewakili. Data …

Penelitian Genom Dan Implikasinya Dalam Kesehatan Masyarakat Di Indonesia, Doni Hikmat Ramdhan

Kesmas

Penelitian genom yang mengkaji kaitan antara setiap gen dengan suatu penyakit sekaligus mekanismenya untuk mendapatkan pengetahuan yang menyeluruh dalam pengobatan, telah membawa perubahan besar dunia kedokteran dalam mengobati berbagai penyakit. Namun demikian, penelitian genom seharusnya tidak hanya dimanfaatkan untuk pengobatan tetapi juga untuk pencegahan penyakit. Artikel ini membahas masalah kesehatan masyarakat dan peluang pemanfaatan penelitian genom dalam pencegahan penyakit. Penelitian genom yang dapat dimanfaatkan pada bidang kesehatan masyarakat adalah toksikogenomik dan nutrigenomik. Penelitian toksikogenomik mengkaji respons gen akibat pajanan toksikan yang berdampak pada kesehatan manusia. Penelitian nutrigenomik mengkaji respons gen terhadap makanan yang berdampak pada kesehatan manusia. Penelitian toksikogenomik dan …

Pengaruh Pendekatan Child Healthcare Modeldan Transtheoretical Model Terhadap Asupan Makan Anak Overweight Dan Obesitas, Kadek Ayu Erika, Elly Nurachmah

Kesmas

Overweight dan obesitas pada anak merupakan suatu masalah yang kompleks disebabkan multifaktor, yaitu interaksi genetik dan lingkungan. Gaya hidup perkotaan dipicu oleh asupan makanan yang berlebih pada anak overweight dan obesitas. Strategi untuk menurunkan asupan makan berlebih pada anak adalah dengan pendekatan child healthcare model dan transtheoretical model sehingga dapat mengendalikan gaya hidup anak. Penelitian ini bertujuan membuktikan pengaruh pendekatan child healthcare dan transtheoretical model terhadap asupan karbohidrat anak overweight dan obesitas. Penelitian ini dilaksanakan di wilayah kecamatan Biringkanaya dan Tamalanrea, Makassar, pada bulan Agustus 2013 sampai Maret 2014. Desain yang digunakan adalah quasy experiment yaitu pretest and posttest with …

Tingkat Pengetahuan Dan Persepsi Terhadap Shisha Pada Mahasiswa, Dhimas Nirwana Yudha, Yayi Suryo Prabandari, Purwanta Purwanta

Kesmas

Isu yang berkembang terkait pengetahuan dan persepsi seorang calon tenaga kesehatan memengaruhi keberhasilan pelayanan kesehatan dalam menjawab tantangan di masyarakat nantinya. Shisha (rokok dari Timur Tengah) mulai marak di Yogyakarta. Tujuan penelitian ini untuk memperoleh gambaran tentang tingkat pengetahuan dan persepsi terhadap shisha pada mahasiswa reguler tahap akademik Fakultas Kedokteran Universitas Gadjah Mada. Penelitian ini merupakan penelitian deskriptif menggunakan rancangan potong lintang. Sampel penelitian adalah mahasiswa dari tiga program studi yang dilakukan pada bulan September - Oktober 2013. Jumlah responden sebanyak 72 mahasiswa ilmu keperawatan, 74 mahasiswa gizi dan kesehatan dan 258 mahasiswa pendidikan dokter. Pengumpulan data dilakukan dengan kuesioner. …

Diagnosis Dini Tuberkulosis Pada Kontak Serumah Dengan Penderita Tuberkulosis Paru Melalui Deteksi Kadar Ifn-Γ, Sri Andarini Indreswari, Suharyo Suharyo

Kesmas

Tuberkulosis paru masih merupakan masalah dunia. Indonesia menempati peringkat ke tiga di dunia pada tahun 2012. Target nasional Case Detection Rate tahun 2012 adalah 70%, sedangkan pencapaian Jawa Tengah sebesar 58,48%. Penelitian ini bertujuan untuk memperoleh batas kadar interferon (IFN) γ pada orang kontak serumah dengan penderita tuberkulosis paru sebagai dasar diagnosis dini penyakit tuberkulosis. Penelitian dilakukan secara kohort selama dua tahun (2011 - 2013) di Balai Kesehatan Masyarakat Paru Semarang. Pada akhir penelitian, terdapat 12 responden kontak dan 13 tidak kontak serumah. Uji Wilcoxon menunjukkan perbedaan bermakna rerata kadar IFN-γ antara kelompok kontak dengan kelompok tidak kontak serumah (nilai …

Peningkatan Determinan Sosial Dalam Menurunkan Kejadian Tuberkulosis Paru, Dyah Wulan Sumekar Rengganis Wardani

Kesmas

Upaya pengendalian tuberkulosis paru oleh World Health Organization telah meningkatkan angka kesembuhan dan menyelamatkan banyak jiwa, tetapi kurang berhasil dalam menurunkan insiden tuberkulosis. Oleh karena itu, pengendalian tuberkulosis akan lebih menekankan pada kebijakan determinan sosial karena determinan sosial secara langsung maupun melalui faktor risiko tuberkulosis berpengaruh terhadap tuberkulosis. Di Bandar Lampung, angka notifikasi tuberkulosis dari tahun 2009 – 2010 mengalami peningkatan walaupun angka kesembuhan sudah lebih dari 85%. Bandar Lampung juga merupakan bagian dari salah satu provinsi termiskin di Indonesia. Penelitian ini bertujuan untuk mempelajari pengaruh determinan sosial (yang diukur melalui indikator pendidikan, pendapatan dan kelas sosial) terhadap kejadian tuberkulosis. …

Pertumbuhan Dan Perkembangan Anak Usia 3-24 Bulan Di Daerah Konflik, Hastuti Usman, Hadyana Sukandar, Ma’Mun Sutisna

Kesmas

Lima tahun pertama adalah masa penting dalam proses tumbuh kembang anak. Anak lahir dan tinggal di daerah rawan bencana (bencana alam, perang, atau konflik bersenjata) berisiko mengalami kegagalan pertumbuhan dan keterlambatan perkembangan. Penelitian ini bertujuan mengukur perbedaan pertumbuhan dan perkembangan anak usia 3 - 24 bulan antara yang tinggal di daerah konflik dan bukan konflik dan menganalisis korelasi tempat tinggal daerah konflik dengan pertumbuhan serta perkembangan anak usia 3 - 24 bulan. Metode penelitian secara potong lintang dilakukan di Kabupaten Poso periode Februari - Maret 2014 terhadap 40 anak usia 3 - 24 bulan di daerah konflik dan bukan konflik. …

Malnutrisi Akut Berat Dan Determinannya Pada Balita Di Wilayah Rural Dan Urban, Titih Huriah, Laksono Trisnantoro, Fitri Haryanti, Madarina Julia

Kesmas

Malnutrisi akut berat merupakan malnutrisi yang paling serius yang memengaruhi balita dan merupakan masalah kesehatan utama di negara-negara berkembang. Malnutrisi telah meluas baik di perkotaan maupun perdesaan. Akar permasalahan malnutrisi di negara berkembang salah satunya adalah faktor sosial demografi. Tujuan penelitian untuk melihat perbedaan kejadian malnutrisi dan determinannya di area perkotaan dan pedesaan di Yogyakarta. Penelitian menggunakan desain potong lintang dengan responden adalah semua balita malnutrisi akut berat di Kabupaten Sleman (23 balita) dan Kota Yogyakarta (33 balita). Analisis data menggunakan statistik deskriptif dan inferensial. Penelitian dilaksanakan pada Bulan Desember 2012 - Februari 2013. Prevalensi balita malnutrisi akut lebih banyak …

Pendapatan Daerah, Pembiayaan Kesehatan, Dan Gizi Buruk Pada Balita: Studi Korelasi Tingkat Kabupaten/Kota, Septyana Choirunisa, Asri C. Adisasmita

Kesmas

Pendanaan kesehatan merupakan salah satu faktor penting dalam memengaruhi derajat kesehatan, termasuk salah satu masalah gizi pada balita yang disebut gizi buruk. Oleh karena itu, penelitian ini bertujuan mendeskripsikan pendapatan daerah dan pembiayaan kesehatan serta korelasinya dengan gizi buruk pada balita di tingkat kabupaten/kota di Indonesia tahun 2007. Penelitian ini merupakan studi ekologi/korelasi. Data pendapatan daerah dan pembiayaan kesehatan didapat dari Kementerian Keuangan, sedangkan data gizi buruk menggunakan data Riset Kesehatan Nasional tahun 2007. Sebanyak 250 kabupaten/kota yang diteliti dengan tidak mengikutsertakan kabupaten/kota yang datanya tidak lengkap atau tidak valid. Secara nasional, hanya persentase pendapatan asli daerah (PAD) per total …

Evaluasi Pelaksanaan Konseling Menyusui, Ika Murtiyarini, Dewi Marhaeni Diah Herawati, Irvan Afriandi

Kesmas

Salah satu upaya pemerintah dalam meningkatkan pemberian ASI di Indonesia adalah dengan memberikan konseling menyusui di pelayanan kesehatan. Penelitian perlu dilakukan untuk mengevaluasi pelaksanaan konseling menyusui di Kota Jambi dengan mengeksplorasi komponen input, activity, output, dan outcome. Penelitian ini merupakan penelitian kualitatif menggunakan strategi studi kasus. Penelitian dilakukan di empat puskesmas Kota Jambi pada bulan Desember 2013 sampai dengan Februari 2014. Pengumpulan data dilakukan dengan studi dokumen, observasi pelaksanaan konseling menyusui dan sarana prasarana, wawancara mendalam, serta focus group discussion. Analisis data yang digunakan adalah analisis tematik. Hasil penelitian menunjukkan bahwa komponen input dan activity kurang optimal seperti kurangnya sumber …

Pattern Of Household Drug Storage, Retno Gitawati

Kesmas

Household storage of pharmaceutical is world-widely practice, including in Indonesia. The purpose of this study was to obtain the pattern of medicine storage, the sources and reasons of medicine kept in households. Acrosssectional survey was conducted on October 2011, involving 250 adult household respondents, randomly selected from three subdistricts in North Jakarta, and have approved the written consents, and interviewed with structured questionnaire. Data were performed in univariate and bivariate analysis with chi square test. The majority of household (82%) stored drugs at home; analgesic-antipyretic nonsteroidal anti-inflammatory was the type of drugs kept by mostly (76.1%) of household. Out of …

Family Role Towards Smoking Behaviour Among Children In Jakarta, Wahyu Septiono, Dan Wolf Meyrowitsch

Kesmas

In Indonesia, the prevalence of smoking among 5 – 9 years old children has increased from 0.4% in 2001 to 2% in 2007. Among present adults smokers (>20 years), 17% started to smoke before the age of 13 years. This study identified factors related to smoking behaviour among 8 – 12 years old children in Jakarta, Indonesia using a questionnaire based cross sectional survey to obtain smoking status and possible predictors towards smoking habit. The total sample size was 1,097 students among 3rd - 7th grade students from schools in Jakarta. Self-reported smoking status was defined as whether the …

Asupan Karbohidrat Sebagai Faktor Dominan Yang Berhubungan Dengan Kadar Gula Darah Puasa, Aprilya Roza Werdani, Triyanti Triyanti

Kesmas

Peningkatan kadar gula darah memicu peningkatan produksi hormon insulin yang erat hubungannya dengan diabetes melitus. Berdasarkan data Riskesdas, prevalensi diabetes melitus di Indonesia meningkat dari 1,1% (2007) menjadi 2,1% (2013). Penelitian ini bertujuan untuk mengetahui faktor dominan yang berhubungan dengan kadar gula darah puasa pegawai pemberdayaan masyarakat & keluarga dan pegawai sekretariat daerah Kota Depok. Desain penelitian yang digunakan adalah potong lintang dan melibatkan 105 sampel. Variabel independen penelitian meliputi karakteristik individu, asupan zat gizi, hipertensi, aktivitas fisik, status gizi dan pengetahuan gizi. Analisis data yang dilakukan adalah analisis univariat, analisis bivariat menggunakan uji korelasi dan uji beda dua mean, …

Asupan Vitamin D Rendah Dan Keparahan Demam Berdarah Dengue Pada Anak Usia 1-14 Tahun, Nur Siyam, Siswanto Agus Wilopo, Mohammad Hakimi

Kesmas

Demam berdarah dengue (DBD) menimbulkan syok dan kematian. Penderita DBD di Yogyakarta sebagian besar usia 1 - 12 tahun dengan DBD parah. Asupan vitamin D rendah diasumsikan penyebab DBD parah. Asumsi ini perlu dibuktikan dengan menganalisis pengaruh asupan Vitamin D dan keparahan DBD. Rancangan penelitian adalah studi kasus kontrol. Penelitian di bangsal rawat inap anak dan instalasi catatan medik RS Jogja dan RSUP Dr. Sardjito. Kasus adalah anak usia 1 - 14 tahun dengan DBD grade III & IV, kontrolnya DBD grade I & II. Data asupan vitamin D diambil dengan food frequency questionnaire (FFQ). Variabel luar adalah indeks massa …

Fertilitas Remaja Di Indonesia, Mugia Bayu Raharja

Kesmas

Fertilitas remaja merupakan isu penting dari segi kesehatan dan sosial karena berhubungan dengan tingkat morbiditas serta mortalitas ibu dan anak. Tujuan penelitian adalah mempelajari faktor-faktor yang memengaruhi fertilitas remaja di Indonesia. Data yang digunakan adalah hasil Survei Demografi dan Kesehatan Indonesia tahun 2012 dengan unit analisis wanita usia subur yang termasuk dalam kategori usia remaja (15 - 19 tahun). Jumlah sampel sebanyak 6.927 responden. Analisis dilakukan dengan metode deskriptif dan inferensial menggunakan model regresi logistik biner. Hasil analisis menunjukkan bahwa satu dari sepuluh remaja wanita tersebut pernah melahirkan dan atau sedang hamil saat survei dilakukan; sebesar 95,2% dari remaja yang …

Molecular Docking Of Known Carcinogen 4- (Methyl-Nitrosamino)-1-(3-Pyridyl)-1-Butanone (Nnk) With Cyclin Dependent Kinases Towards Its Potential Role In Cell Cycle Perturbation, Mohd Haneef, Mohtashim Lohani, Anupam Dhasmana, Qazi Mohammad Sajid Jamal, S. M. A. Shahid, Sumbul Firdaus

School of Medicine Publications

Cell cycle is maintained almost all the times and is controlled by various regulatory proteins and their complexes (Cdk+Cyclin) in different phases of interphase (G1, S and G2) and mitosis of cell cycle. A number of mechanisms have been proposed for the initiation and progression of carcinogenesis by abruption in cell cycle process. One of the important features of cancer/carcinogenesis is functional loss of these cell cycle regulatory proteins particularly in CDKs and cyclins. We hypothesize that there is a direct involvement of these cell cycle regulatory proteins not only at the genetic level but also proteins level, during the …